Name |
Prostaglandin E2 receptor EP4 subtype |
Synonyms |
7749 |
Gene name |
PTGER4 |
General function |
Not Available |
Specific function |
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function |
Gene sequence |
+ ...
Not Available
|
Protein sequence |
+ ...
MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSGQHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPGMGLAQEDTTSLRTLRISETSDSSQGQDSESVLLVDEAGGSGRAGPAPKGSSLQVTFPSETLNLSEKCI
|
GO Classification |
component |
cell |
intrinsic to membrane |
integral to membrane |
membrane |
function |
icosanoid receptor activity |
prostanoid receptor activity |
prostaglandin receptor activity |
signal transducer activity |
prostaglandin E receptor activity |
receptor activity |
transmembrane receptor activity |
G-protein coupled receptor activity |
rhodopsin-like receptor activity |
process |
cellular process |
cell communication |
signal transduction |
cell surface receptor linked signal transduction |
G-protein coupled receptor protein signaling pathway |
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