DT-Web

DB08804 - Nandrolone decanoate


Identification
Name Nandrolone decanoate
Accession Number DB08804
Type small molecule
Description C18 steroid with androgenic and anabolic properties. It is generally prepared from alkyl ethers of estradiol to resemble testosterone but less one carbon at the 19 position. It is a schedule III drug in the U.S.
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 428.6472
Groups illicit
Monoisotopic Weight 428.329045274
Pharmacology
Indication For the treatment of refractory deficient red cell production anemias, breast carcinoma, hereditary angioedema, antithrombin III deficiency, fibrinogen excess, growth failure and Turner's syndrome. It is also indicated in the prophylaxis of hereditary angioedema.
Mechanism of action Nandrolone is an androgen receptor agonist. The drug bound to the receptor complexes which allows it to enter the nucleus and bind directly to specific nucleotide sequences of the chromosomal DNA. The areas of binding are called hormone response elements (HREs), and influence transcriptional activity of certain genes, producing the androgen effects.
Absorption Not Available
Protein binding 58%
Biotransformation Nandrolone is unusual in that unlike most anabolic steroids, it is not broken down into the more reactive DHT by the enzyme 5?-reductase, but rather into a less effective product known as Dihydronandrolone.
Route of elimination Not Available
Toxicity Not Available
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions
Drug Mechanism of interaction
Warfarin Nandrolone may increase the serum concentration and anticoagulant effect of warfarin. Monitor for changes in prothrombin time and therapeutic effects of warfarin if nandrolone is initiated, discontinued or dose changed.
Food Interactions Not Available

Targets


Androgen receptor
Name Androgen receptor
Gene Name AR
Pharmacological action yes
Actions agonist
References
  • Birgner C, Kindlundh-Hogberg AM, Alsio J, Lindblom J, Schioth HB, Bergstrom L: The anabolic androgenic steroid nandrolone decanoate affects mRNA expression of dopaminergic but not serotonergic receptors. Brain Res. 2008 Nov 13;1240:221-8. Epub 2008 Sep 13. - Pubmed
DTHybrid score 1.11

Enzymes


Cytochrome P450 19A1
Name Cytochrome P450 19A1
Gene Name CYP19A1
Actions inducer
References
  • Takahashi K, Hallberg M, Magnusson K, Nyberg F, Watanabe Y, Langstrom B, Bergstrom M: Increase in [11C]vorozole binding to aromatase in the hypothalamus in rats treated with anabolic androgenic steroids. Neuroreport. 2007 Jan 22;18(2):171-4. - Pubmed
DTHybrid score 0.393
Amine oxidase [flavin-containing] B
Name Amine oxidase [flavin-containing] B
Gene Name MAOB
Actions inhibitor
References
  • Birgner C, Kindlundh-Hogberg AM, Oreland L, Alsio J, Lindblom J, Schioth HB, Bergstrom L: Reduced activity of monoamine oxidase in the rat brain following repeated nandrolone decanoate administration. Brain Res. 2008 Jul 11;1219:103-10. Epub 2008 May 17. - Pubmed
DTHybrid score 0.9632
Amine oxidase [flavin-containing] A
Name Amine oxidase [flavin-containing] A
Gene Name MAOA
Actions inhibitor
References
  • Birgner C, Kindlundh-Hogberg AM, Oreland L, Alsio J, Lindblom J, Schioth HB, Bergstrom L: Reduced activity of monoamine oxidase in the rat brain following repeated nandrolone decanoate administration. Brain Res. 2008 Jul 11;1219:103-10. Epub 2008 May 17. - Pubmed
DTHybrid score 0.5582

Predictions


Id Partner name Gene Name Score
4512 Cytochrome P450 3A4 CYP3A4 0.0916
4200 Cytochrome P450 1A2 CYP1A2 0.0791
756 Sex hormone-binding globulin SHBG 0.0683
6016 Cytochrome P450 2C19 CYP2C19 0.061
824 Sodium-dependent serotonin transporter SLC6A4 0.0598
713 Sodium-dependent dopamine transporter SLC6A3 0.0582
4757 Cytochrome P450 2C9 CYP2C9 0.0547
4119 Cytochrome P450 2D6 CYP2D6 0.054
1588 Multidrug resistance protein 1 ABCB1 0.0488
136 Estrogen receptor ESR1 0.0464
3810 Catechol O-methyltransferase COMT 0.0433
614 Progesterone receptor PGR 0.0393
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0389
4924 Cytochrome P450 2C8 CYP2C8 0.0363
6013 Cytochrome P450 2E1 CYP2E1 0.0357
131 Synaptic vesicular amine transporter SLC18A2 0.0348
6030 Cytochrome P450 2B6 CYP2B6 0.0326
511 5-hydroxytryptamine 1F receptor HTR1F 0.0325
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0314
5718 Cytochrome P450 2A6 CYP2A6 0.0287
737 Mineralocorticoid receptor NR3C2 0.0267
725 5-hydroxytryptamine 1D receptor HTR1D 0.0262
885 5-hydroxytryptamine 1B receptor HTR1B 0.0258
226 Gonadotropin-releasing hormone receptor GNRHR 0.0248
318 Alpha-2A adrenergic receptor ADRA2A 0.024
871 Glucocorticoid receptor NR3C1 0.0239
2864 Penton protein PIII 0.0236
260 Cytochrome P450 51 ERG11 0.0214
761 Cytochrome P450 51 ERG11 0.0214
3163 Cytochrome P450 51 cyp51 0.0214
563 Thyroid peroxidase TPO 0.0207
5841 Insulin-like growth factor IB IGF1 0.0206
4116 Dihydropteroate synthetase Not Available 0.0199
556 Alpha-1A adrenergic receptor ADRA1A 0.0195
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0183
4118 Cytochrome P450 3A5 CYP3A5 0.0178
148 Lutropin-choriogonadotropic hormone receptor LHCGR 0.0175
273 Apoptosis regulator Bcl-2 BCL2 0.017
596 3-oxo-5-alpha-steroid 4-dehydrogenase 1 SRD5A1 0.0161
6107 Cytochrome P450 3A7 CYP3A7 0.0152
629 Alpha-2B adrenergic receptor ADRA2B 0.0147
1656 CYP2B protein CYP2B 0.0143
320 5-hydroxytryptamine 1A receptor HTR1A 0.0143
6024 Cytochrome P450 1A1 CYP1A1 0.0139
193 Beta-1 adrenergic receptor ADRB1 0.0137
6147 Solute carrier family 22 member 3 SLC22A3 0.0137
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0136
290 Prostaglandin G/H synthase 2 PTGS2 0.0133
380 Cytochrome P450 17A1 CYP17A1 0.0131
1757 Myeloperoxidase MPO 0.0131
381 Prolactin receptor PRLR 0.013
6241 Nuclear receptor coactivator 2 NCOA2 0.013
1649 Small inducible cytokine A2 CCL2 0.0125
3923 Cholinesterase BCHE 0.0125
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0123
1898 Cytochrome P450 1B1 CYP1B1 0.0122
6044 Serum paraoxonase/lactonase 3 PON3 0.0118
6145 Solute carrier family 22 member 1 SLC22A1 0.0116
6142 Solute carrier family 22 member 8 SLC22A8 0.0112
23 D(1A) dopamine receptor DRD1 0.0108
6031 Cytochrome P450 3A43 CYP3A43 0.0108
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0108
5698 Riboflavin synthase alpha chain ribE 0.0105
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0105
502 5-hydroxytryptamine 2A receptor HTR2A 0.0104
587 Serum albumin ALB 0.0103
378 Alpha-2C adrenergic receptor ADRA2C 0.0102
408 Riboflavin kinase RFK 0.0101
1181 Alpha-1-acid glycoprotein 1 ORM1 0.01
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0092
118 Organic cation/carnitine transporter 2 SLC22A5 0.009
6144 Solute carrier family 22 member 2 SLC22A2 0.0089
831 D(2) dopamine receptor DRD2 0.0087
6014 Cytochrome P450 2A13 CYP2A13 0.0087
1729 Solute carrier family 22 member 6 SLC22A6 0.0086
4120 NADPH--cytochrome P450 reductase POR 0.0084
766 Beta-2 adrenergic receptor ADRB2 0.0083
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0083
1636 Trace amine-associated receptor 1 TAAR1 0.0081
3913 Glutamic acid decarboxylase GAD65 0.008
869 Estrogen receptor beta ESR2 0.0079
3957 Adenosine deaminase ADA 0.0079
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0078
1680 Solute carrier family 2, facilitated glucose transporter member 1 SLC2A1 0.0078
1483 Membrane copper amine oxidase AOC3 0.0076
373 Transthyretin TTR 0.0076
654 Flavin reductase BLVRB 0.0075
1517 Beta-3 adrenergic receptor ADRB3 0.0072
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0071
6020 Aldehyde oxidase AOX1 0.0068
789 Alpha-1D adrenergic receptor ADRA1D 0.0068
3917 Methylenetetrahydrofolate reductase MTHFR 0.0066
735 Alanine aminotransferase 1 GPT 0.0065
3904 Alanine aminotransferase 2 GPT2 0.0065
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0065
474 Acetylcholinesterase ACHE 0.0063
20 Prostaglandin G/H synthase 1 PTGS1 0.0062
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0061
632 Alpha-1B adrenergic receptor ADRA1B 0.0061
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.006
694 Matrix protein 2 M 0.0059
3947 Xanthine dehydrogenase/oxidase XDH 0.0058
833 Organic cation/carnitine transporter 1 SLC22A4 0.0056
847 Mu-type opioid receptor OPRM1 0.0056
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0056
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0055
6220 Aryl hydrocarbon receptor AHR 0.0053
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0052
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0052
3876 Aromatic-L-amino-acid decarboxylase DDC 0.005
144 Hemoglobin subunit alpha HBA1 0.0049
3809 Estrogen-related receptor gamma ESRRG 0.0048
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0047
153 Dopamine beta-hydroxylase DBH 0.0047
776 Bile salt export pump ABCB11 0.0047
5934 Cytochrome P450 26A1 CYP26A1 0.0047
1010 Cytochrome P450 51A1 CYP51A1 0.0046
1178 Adenosine A2a receptor ADORA2A 0.0045
6143 Solute carrier family 22 member 7 SLC22A7 0.0043
780 Retinoic acid receptor RXR-gamma RXRG 0.0043
229 Retinoic acid receptor beta RARB 0.0043
634 Squalene monooxygenase SQLE 0.0043
7196 Squalene monooxygenase ERG1 0.0043
730 Retinoic acid receptor alpha RARA 0.0042
6141 Sodium/bile acid cotransporter SLC10A1 0.0041
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.004
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.004
459 Retinoic acid receptor RXR-alpha RXRA 0.004
88 Retinoic acid receptor RXR-beta RXRB 0.0039
162 Retinoic acid receptor gamma-1 RARG 0.0039
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0038
6133 Sodium channel subunit beta-2 SCN2B 0.0038
6134 Sodium channel subunit beta-3 SCN3B 0.0038
6132 Sodium channel subunit beta-1 SCN1B 0.0038
6135 Sodium channel subunit beta-4 SCN4B 0.0038
6127 Carbonic anhydrase-related protein CA8 0.0038
6129 Carbonic anhydrase-related protein 11 CA11 0.0038
6128 Carbonic anhydrase-related protein 10 CA10 0.0038
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0038
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0038
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0038
2782 Complement C1s subcomponent C1S 0.0037
163 D(1B) dopamine receptor DRD5 0.0036
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.0036
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0036
6130 Carbonic anhydrase 13 CA13 0.0036
436 5-hydroxytryptamine 2B receptor HTR2B 0.0036
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0035
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.0035
432 D(4) dopamine receptor DRD4 0.0035
3815 Complement C1q subcomponent subunit A C1QA 0.0034
3816 Complement C1q subcomponent subunit B C1QB 0.0034
3817 Complement C1q subcomponent subunit C C1QC 0.0034
3818 Low affinity immunoglobulin gamma Fc region receptor III-A FCGR3A 0.0034
3819 Low affinity immunoglobulin gamma Fc region receptor II-a FCGR2A 0.0034
1102 Low affinity immunoglobulin gamma Fc region receptor III-B FCGR3B 0.0034
3821 Low affinity immunoglobulin gamma Fc region receptor II-c FCGR2C 0.0034
3814 Complement C1r subcomponent C1R 0.0034
3830 Calreticulin CALR 0.0034
638 D(3) dopamine receptor DRD3 0.0034
3820 Low affinity immunoglobulin gamma Fc region receptor II-b FCGR2B 0.0034
215 Sodium channel protein type 11 subunit alpha SCN11A 0.0032
6131 Carbonic anhydrase 14 CA14 0.0032
784 High affinity immunoglobulin gamma Fc receptor I FCGR1A 0.0032
6035 Nuclear receptor ROR-beta RORB 0.0032
6034 Hydroxyindole O-methyltransferase ASMT 0.0032
6036 Eosinophil peroxidase EPX 0.0032
590 5-hydroxytryptamine 2C receptor HTR2C 0.0031
6122 Carbonic anhydrase 3 CA3 0.0031
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0031
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.003
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.003
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0029
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0029
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0029
844 Epidermal growth factor receptor EGFR 0.0028
4205 Carbonic anhydrase 9 CA9 0.0028
3007 Carbonic anhydrase 12 CA12 0.0028
765 Indoleamine 2,3-dioxygenase IDO1 0.0027
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0027
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0026
6126 Carbonic anhydrase 7 CA7 0.0026
571 Melatonin receptor type 1A MTNR1A 0.0026
362 Melatonin receptor type 1B MTNR1B 0.0026
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0025
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0025
5923 Microtubule-associated protein tau MAPT 0.0024
5924 Microtubule-associated protein 4 MAP4 0.0024
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0023
267 Plasminogen activator inhibitor 1 SERPINE1 0.0023
1852 Microtubule-associated protein 2 MAP2 0.0023
7 Nitric oxide synthase, inducible NOS2 0.0022
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0022
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0022
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0022
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0022
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0022
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0022
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0022
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0022
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0022
6221 Steroid hormone receptor ERR1 ESRRA 0.0021
592 Carbonic anhydrase 4 CA4 0.0021
295 Carbonic anhydrase 1 CA1 0.002
6002 Prostaglandin E2 receptor EP4 subtype PTGER4 0.002
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.0019
29 Tubulin beta-1 chain TUBB1 0.0019
84 Nuclear receptor 0B1 NR0B1 0.0019
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0019
4131 Prostaglandin E2 receptor, EP3 subtype PTGER3 0.0018
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.0018
406 Prostaglandin E2 receptor, EP2 subtype PTGER2 0.0018
6106 Cytochrome P450 2C18 CYP2C18 0.0018
469 Annexin A1 ANXA1 0.0018
6167 Organic solute transporter subunit beta OSTB 0.0018
6166 Organic solute transporter subunit alpha OSTA 0.0018
467 Delta-type opioid receptor OPRD1 0.0018
1192 Sulfotransferase 1A1 SULT1A1 0.0018
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0018
4486 Phenol 2-hydroxylase component B pheA2 0.0018
4477 Dihydrolipoyl dehydrogenase lpdV 0.0018
5077 Dihydrolipoyl dehydrogenase Not Available 0.0018
5117 Dihydrolipoyl dehydrogenase lpd 0.0018
4439 Ferredoxin reductase bphA4 0.0018
5078 Amine oxidase, flavin-containing PSPTO1126 0.0018
526 Thioredoxin reductase trxB 0.0018
3767 Thioredoxin reductase trxB 0.0018
5122 Mersacidin decarboxylase mrsD 0.0017
5095 Putidaredoxin reductase camA 0.0017
5107 Alkyl hydroperoxide reductase subunit F ahpF 0.0017
5118 Alkyl hydroperoxide reductase subunit F ahpF 0.0017
5114 Putative acyl-CoA dehydrogenase TT_C0779 0.0017
5109 Outer membrane protein p64k or PM-6 m-6 0.0017
5115 FkbI fkbI 0.0017
3133 UDP-galactopyranose mutase glf 0.0017
5099 UDP-galactopyranose mutase glf 0.0017
5097 PROBABLE DIHYDROLIPOAMIDE DEHYDROGENASE LPDA lpdA 0.0017
3763 5,10-methylenetetrahydrofolate reductase metF 0.0017
3918 5,10-methylenetetrahydrofolate reductase MTHFR 0.0017
5094 5,10-methylenetetrahydrofolate reductase metF 0.0017
5102 4-cresol dehydrogenase [hydroxylating] flavoprotein subunit pchF 0.0017
5111 Phenylacetone monooxygenase pamO 0.0017
1329 Apoptosis-inducing factor 1, mitochondrial AIFM1 0.0017
5083 Cryptochrome DASH cry 0.0017
5100 Gamma-aminobutyrate metabolism dehydratase/isomerase abfD 0.0017
5081 L-aspartate oxidase nadB 0.0017
1410 Oxidoreductase HSD17B6 0.0017
4725 Oxidoreductase Not Available 0.0017
5124 Oxidoreductase Not Available 0.0017
5112 Benzoate 1,2-dioxygenase electron transfer component benC 0.0017
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0017
465 Calmodulin CALM1 0.0017
357 Carbonic anhydrase 2 CA2 0.0017
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0016
6148 Multidrug resistance-associated protein 7 ABCC10 0.0016
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0016
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0016
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0016
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0015
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0015
4440 NADH peroxidase npr 0.0015
5091 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0015
5093 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0015
3102 Flavohemoprotein hmp 0.0015
4969 Flavohemoprotein hmp 0.0015
3594 Deoxyribodipyrimidine photo-lyase phr 0.0015
5079 Deoxyribodipyrimidine photo-lyase phrB 0.0015
5080 Deoxyribodipyrimidine photo-lyase phr 0.0015
5072 N,N-dimethylglycine oxidase dmg 0.0015
2470 Pyruvate oxidase pox5 0.0015
5073 Ferredoxin--NADP reductase petH 0.0015
5076 Ferredoxin--NADP reductase fpr 0.0015
5119 Ferredoxin--NADP reductase petH 0.0015
5121 Ferredoxin--NADP reductase fpr 0.0015
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0015
440 Isovaleryl-CoA dehydrogenase, mitochondrial IVD 0.0015
667 Acyl-CoA dehydrogenase family member 8, mitochondrial ACAD8 0.0015
3506 Glutaryl-CoA dehydrogenase, mitochondrial GCDH 0.0015
5003 Acyl-CoA dehydrogenase, short-chain specific Not Available 0.0015
2268 Cholesterol oxidase choB 0.0015
2822 Cholesterol oxidase choA 0.0015
2526 NADPH-ferredoxin reductase fprA fprA 0.0015
6639 Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 0.0015
3247 2-oxopropyl-CoM reductase, carboxylating xecC 0.0015
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0015
6689 TraN protein traN 0.0015
6672 Destrin DSTN 0.0015
6680 Cofilin-1 CFL1 0.0015
6670 Ig kappa chain V-I region Bi Not Available 0.0015
6671 Ig heavy chain V-III region VH26 Not Available 0.0015
4905 Cytochrome c2 Not Available 0.0015
4939 Cytochrome c2 cycA 0.0015
4964 Cytochrome c2 cycA 0.0015
4979 Cytochrome c2 cycA 0.0015
6673 Cytochrome c2 cycA 0.0015
6688 TraF protein traF 0.0015
6404 Rhomboid protease glpG glpG 0.0015
6797 Rhomboid protease glpG glpG 0.0015
3710 Acyl-CoA thioesterase 2 tesB 0.0015
6685 Outer membrane protein II porB 0.0015
6690 BenF-like porin PFL_1329 0.0015
6681 Probable N-acetylneuraminic acid outer membrane channel protein nanC nanC 0.0015
6687 TraO protein traO 0.0015
5793 Cytochrome c oxidase subunit 2 MT-CO2 0.0015
6559 Cytochrome c oxidase subunit 2 ctaC 0.0015
6669 Cytochrome c oxidase subunit 2 ctaC 0.0015
6668 Cytochrome c oxidase subunit 1-beta ctaDII 0.0015
6679 Colicin-Ia cia 0.0015
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0015
6676 Fe(3+)-pyochelin receptor fptA 0.0015
115 Penicillin-binding protein 2 mrdA 0.0015
6069 Penicillin-binding protein 2 mrdA 0.0015
6118 Penicillin-binding protein 2 penA 0.0015
6187 Penicillin-binding protein 2 pbpA 0.0015
6686 Penicillin-binding protein 2 pbp2 0.0015
6939 Penicillin-binding protein 2 mrdA 0.0015
7163 Penicillin-binding protein 2 pbpA 0.0015
6674 Nuclear factor erythroid 2-related factor 1 NFE2L1 0.0015
327 Glutathione reductase gor 0.0015
5110 Glutathione reductase GR2 0.0015
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0015
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0015
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0014
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0014
126 D-lactate dehydrogenase dld 0.0014
3545 D-lactate dehydrogenase Not Available 0.0014
4510 D-lactate dehydrogenase ldhA 0.0014
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0014
3185 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM 0.0014
3254 Bifunctional protein putA [Includes: Proline dehydrogenase putA 0.0014
2893 Glycine oxidase thiO 0.0014
605 Fumarate reductase flavoprotein subunit frdA 0.0014
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0014
3673 Fumarate reductase flavoprotein subunit fccA 0.0014
4912 Fumarate reductase flavoprotein subunit ifcA 0.0014
6549 Fumarate reductase flavoprotein subunit frdA 0.0014
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0014
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0014
468 Cytochrome P450 4A11 CYP4A11 0.0014
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0013
2567 Thymidylate synthase thyX thyX 0.0013
6136 Multidrug resistance-associated protein 5 ABCC5 0.0013
2823 Trypanothione reductase TPR 0.0013
2769 P-hydroxybenzoate hydroxylase pobA 0.0013
2809 P-hydroxybenzoate hydroxylase pobA 0.0013
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0013
4760 Mll3241 protein mll3241 0.0013
3395 Iron(III) dicitrate transport protein fecA fecA 0.0013
6385 H subunit of photosynthetic reaction center complex puhA 0.0013
6474 Outer membrane protein W ompW 0.0013
6678 Colicin I receptor cirA 0.0013
3578 Protein crcA crcA 0.0013
6675 Colicin-E3 ceaC 0.0013
2925 Long-chain fatty acid transport protein fadL 0.0013
6480 Outer membrane usher protein papC papC 0.0013
6438 Outer membrane protein G ompG 0.0013
2447 Ammonia channel amtB 0.0013
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0013
862 Multidrug resistance-associated protein 1 ABCC1 0.0013
4604 Liver carboxylesterase 1 CES1 0.0012
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0012
2380 Monomeric sarcosine oxidase soxA 0.0012
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0012
6645 D-amino-acid oxidase DAO 0.0012
6428 Light-harvesting protein B-800/850 beta chain Not Available 0.0012
6427 Light-harvesting protein B-800/850 alpha chain Not Available 0.0012
6533 Light-harvesting protein B-800/850 alpha chain A1 0.0012
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0012
6524 Protein tonB tonB 0.0012
2679 Vitamin B12 transporter btuB btuB 0.0012
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0012
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0012
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0012
1024 Solute carrier family 22 member 11 SLC22A11 0.0011
6677 Myelin P2 protein PMP2 0.0011
2164 Multidrug resistance-associated protein 4 ABCC4 0.0011
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0011
291 Nitric-oxide synthase, endothelial NOS3 0.0011
714 Glutathione reductase, mitochondrial GSR 0.001
6352 Reaction center protein H chain puhA 0.001
6456 Reaction center protein H chain puhA 0.001
6682 Reaction center protein H chain puhA 0.001
6353 Reaction center protein L chain pufL 0.001
6454 Reaction center protein L chain pufL 0.001
6683 Reaction center protein L chain pufL 0.001
6354 Reaction center protein M chain pufM 0.001
6455 Reaction center protein M chain pufM 0.001
6684 Reaction center protein M chain pufM 0.001
6351 Photosynthetic reaction center cytochrome c subunit pufC 0.001
2828 Squalene--hopene cyclase shc 0.0009
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0009
76 Nitric-oxide synthase, brain NOS1 0.0009
2207 Rhodopsin RHO 0.0009
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0008
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