DT-Web

DB06710 - Methyltestosterone


Identification
Name Methyltestosterone
Accession Number DB06710
Type small molecule
Description A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies. Also, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. Methyltestosterone is a schedule III drug in the US.
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 302.451
Groups approved
Monoisotopic Weight 302.224580204
Pharmacology
Indication Methyltestosterone is an anabolic steroid hormone used to treat men with a testosterone deficiency. It is also used in women to treat breast cancer, breast pain, swelling due to pregnancy, and with the addition of estrogen it can treat symptoms of menopause.
Mechanism of action The effects of testosterone in humans and other vertebrates occur by way of two main mechanisms: by activation of the androgen receptor (directly or as DHT), and by conversion to estradiol and activation of certain estrogen receptors. Free testosterone (T) is transported into the cytoplasm of target tissue cells, where it can bind to the androgen receptor, or can be reduced to 5α-dihydrotestosterone (DHT) by the cytoplasmic enzyme 5α-reductase. DHT binds to the same androgen receptor even more strongly than T, so that its androgenic potency is about 2.5 times that of T. The T-receptor or DHT-receptor complex undergoes a structural change that allows it to move into the cell nucleus and bind directly to specific nucleotide sequences of the chromosomal DNA. The areas of binding are called hormone response elements (HREs), and influence transcriptional activity of certain genes, producing the androgen effects.
Absorption The methyl group aids to increase oral bioavailability.
Protein binding 40% of testosterone in plasma is bound to sex hormone-binding globulin and 2% remains unbound and the rest is bound to albumin and other proteins.
Biotransformation Hepatic. Testosterone is metabolized to 17-keto steroids through two different pathways. The major active metabolites are estradiol and dihydrotestosterone (DHT).
Route of elimination 90% urine / 10% feces
Toxicity Side effects include amnesia, anxiety, discolored hair, dizziness, dry skin, hirsutism, hostility, impaired urination, paresthesia, penis disorder, peripheral edema, sweating, and vasodilation.
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Androgen receptor
Name Androgen receptor
Gene Name AR
Pharmacological action yes
Actions agonist
References
  • Small EJ, Ryan CJ: The case for secondary hormonal therapies in the chemotherapy age. J Urol. 2006 Dec;176(6 Pt 2):S66-71. - Pubmed
  • Omwancha J, Brown TR: Selective androgen receptor modulators: in pursuit of tissue-selective androgens. Curr Opin Investig Drugs. 2006 Oct;7(10):873-81. - Pubmed
  • Petraki CD, Sfikas CP: Histopathological changes induced by therapies in the benign prostate and prostate adenocarcinoma. Histol Histopathol. 2007 Jan;22(1):107-18. - Pubmed
  • Maudsley S, Davidson L, Pawson AJ, Freestone SH, Lopez de Maturana R, Thomson AA, Millar RP: Gonadotropin-releasing hormone functionally antagonizes testosterone activation of the human androgen receptor in prostate cells through focal adhesion complexes involving Hic-5. Neuroendocrinology. 2006;84(5):285-300. Epub 2007 Jan 4. - Pubmed
  • Lapauw B, Goemaere S, Crabbe P, Kaufman JM, Ruige JB: Is the effect of testosterone on body composition modulated by the androgen receptor gene CAG repeat polymorphism in elderly men? Eur J Endocrinol. 2007 Mar;156(3):395-401. - Pubmed
  • Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. - Pubmed
DTHybrid score 1.1901

Enzymes


Cytochrome P450 19A1
Name Cytochrome P450 19A1
Gene Name CYP19A1
Actions inducer
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.4652
Cytochrome P450 2B6
Name Cytochrome P450 2B6
Gene Name CYP2B6
Actions substrate
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.2527
Cytochrome P450 3A4
Name Cytochrome P450 3A4
Gene Name CYP3A4
Actions substrate
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.4891

Transporters


Solute carrier organic anion transporter family member 1A2
Name Solute carrier organic anion transporter family member 1A2
Gene Name SLCO1A2
Actions inhibitor,inducer
References
  • Lu R, Kanai N, Bao Y, Wolkoff AW, Schuster VL: Regulation of renal oatp mRNA expression by testosterone. Am J Physiol. 1996 Feb;270(2 Pt 2):F332-7. - Pubmed
  • Kanai N, Lu R, Bao Y, Wolkoff AW, Vore M, Schuster VL: Estradiol 17 beta-D-glucuronide is a high-affinity substrate for oatp organic anion transporter. Am J Physiol. 1996 Feb;270(2 Pt 2):F326-31. - Pubmed
  • Bossuyt X, Muller M, Hagenbuch B, Meier PJ: Polyspecific drug and steroid clearance by an organic anion transporter of mammalian liver. J Pharmacol Exp Ther. 1996 Mar;276(3):891-6. - Pubmed
DTHybrid score 0.2302
Solute carrier family 22 member 8
Name Solute carrier family 22 member 8
Gene Name SLC22A8
Actions inducer
References
  • Kobayashi Y, Hirokawa N, Ohshiro N, Sekine T, Sasaki T, Tokuyama S, Endou H, Yamamoto T: Differential gene expression of organic anion transporters in male and female rats. Biochem Biophys Res Commun. 2002 Jan 11;290(1):482-7. - Pubmed
DTHybrid score 0.2299

Carriers


Solute carrier organic anion transporter family member 1A2
Name Solute carrier organic anion transporter family member 1A2
Gene Name SLCO1A2
Actions
References Not Available
DTHybrid score 0.2302
Solute carrier family 22 member 8
Name Solute carrier family 22 member 8
Gene Name SLC22A8
Actions
References Not Available
DTHybrid score 0.2299

Predictions


Id Partner name Gene Name Score
1588 Multidrug resistance protein 1 ABCB1 0.2117
4757 Cytochrome P450 2C9 CYP2C9 0.1926
6016 Cytochrome P450 2C19 CYP2C19 0.1763
4924 Cytochrome P450 2C8 CYP2C8 0.1564
4200 Cytochrome P450 1A2 CYP1A2 0.1509
4119 Cytochrome P450 2D6 CYP2D6 0.1472
4118 Cytochrome P450 3A5 CYP3A5 0.1374
1729 Solute carrier family 22 member 6 SLC22A6 0.1243
136 Estrogen receptor ESR1 0.1108
6107 Cytochrome P450 3A7 CYP3A7 0.1012
1024 Solute carrier family 22 member 11 SLC22A11 0.0874
6013 Cytochrome P450 2E1 CYP2E1 0.087
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0823
869 Estrogen receptor beta ESR2 0.0767
6143 Solute carrier family 22 member 7 SLC22A7 0.0761
871 Glucocorticoid receptor NR3C1 0.0732
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0721
614 Progesterone receptor PGR 0.0707
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0696
5718 Cytochrome P450 2A6 CYP2A6 0.0656
6024 Cytochrome P450 1A1 CYP1A1 0.0644
20 Prostaglandin G/H synthase 1 PTGS1 0.0615
6145 Solute carrier family 22 member 1 SLC22A1 0.0613
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.061
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0595
290 Prostaglandin G/H synthase 2 PTGS2 0.0585
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0549
1181 Alpha-1-acid glycoprotein 1 ORM1 0.049
862 Multidrug resistance-associated protein 1 ABCC1 0.0483
381 Prolactin receptor PRLR 0.0477
2164 Multidrug resistance-associated protein 4 ABCC4 0.0473
6141 Sodium/bile acid cotransporter SLC10A1 0.0466
776 Bile salt export pump ABCB11 0.0463
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0459
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.044
226 Gonadotropin-releasing hormone receptor GNRHR 0.0391
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0385
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0381
380 Cytochrome P450 17A1 CYP17A1 0.0377
118 Organic cation/carnitine transporter 2 SLC22A5 0.0368
737 Mineralocorticoid receptor NR3C2 0.0365
1898 Cytochrome P450 1B1 CYP1B1 0.0357
232 Corticosteroid-binding globulin SERPINA6 0.0349
269 Adrenodoxin, mitochondrial FDX1 0.0348
260 Cytochrome P450 51 ERG11 0.034
761 Cytochrome P450 51 ERG11 0.034
3163 Cytochrome P450 51 cyp51 0.034
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0333
6144 Solute carrier family 22 member 2 SLC22A2 0.0328
1649 Small inducible cytokine A2 CCL2 0.0299
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0293
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0293
6106 Cytochrome P450 2C18 CYP2C18 0.0292
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0288
3941 Amine oxidase [flavin-containing] A MAOA 0.0283
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0273
492 Histamine H1 receptor HRH1 0.027
3923 Cholinesterase BCHE 0.0268
833 Organic cation/carnitine transporter 1 SLC22A4 0.0257
891 Dihydropteroate synthase folP 0.0245
5359 Dihydropteroate synthase folP 0.0245
7175 Dihydropteroate synthase sulI 0.0245
6147 Solute carrier family 22 member 3 SLC22A3 0.0245
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0242
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0239
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0238
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0238
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0232
563 Thyroid peroxidase TPO 0.0232
847 Mu-type opioid receptor OPRM1 0.0229
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0218
824 Sodium-dependent serotonin transporter SLC6A4 0.0217
731 HIV-1 protease HIV-1 protease 0.0213
4116 Dihydropteroate synthetase Not Available 0.0209
373 Transthyretin TTR 0.0209
502 5-hydroxytryptamine 2A receptor HTR2A 0.0206
6136 Multidrug resistance-associated protein 5 ABCC5 0.0203
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0197
596 3-oxo-5-alpha-steroid 4-dehydrogenase 1 SRD5A1 0.0194
6020 Aldehyde oxidase AOX1 0.0194
33 Cystine/glutamate transporter SLC7A11 0.0193
556 Alpha-1A adrenergic receptor ADRA1A 0.0187
3939 Amine oxidase [flavin-containing] B MAOB 0.0187
469 Annexin A1 ANXA1 0.0185
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0183
738 Monocarboxylate transporter 1 SLC16A1 0.0181
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.018
6031 Cytochrome P450 3A43 CYP3A43 0.0177
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0176
831 D(2) dopamine receptor DRD2 0.0175
148 Lutropin-choriogonadotropic hormone receptor LHCGR 0.0175
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0174
6148 Multidrug resistance-associated protein 7 ABCC10 0.0174
4604 Liver carboxylesterase 1 CES1 0.0171
1389 Transforming growth factor beta-1 TGFB1 0.0169
3810 Catechol O-methyltransferase COMT 0.0168
3947 Xanthine dehydrogenase/oxidase XDH 0.0167
645 Penicillin-binding protein 1A mrcA 0.0162
5805 Penicillin-binding protein 1A ponA 0.0162
6185 Penicillin-binding protein 1A mrcA 0.0162
6799 Penicillin-binding protein 1A pbpA 0.0162
543 Penicillin-binding protein 1B mrcB 0.0158
6186 Penicillin-binding protein 1B ponB 0.0158
6822 Penicillin-binding protein 1b pbp1b 0.0158
6844 Penicillin-binding protein 1b pbp1b 0.0158
468 Cytochrome P450 4A11 CYP4A11 0.0156
244 Angiotensin-converting enzyme ACE 0.0154
320 5-hydroxytryptamine 1A receptor HTR1A 0.0154
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0153
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0153
467 Delta-type opioid receptor OPRD1 0.0152
2261 Major NAD(P)H-flavin oxidoreductase Not Available 0.0149
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0148
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0146
6085 Fatty acid-binding protein, intestinal FABP2 0.0146
6014 Cytochrome P450 2A13 CYP2A13 0.0144
904 Glutathione S-transferase P GSTP1 0.0143
4120 NADPH--cytochrome P450 reductase POR 0.0143
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0142
6541 Peptostreptococcal albumin-binding protein pab 0.0142
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0142
6044 Serum paraoxonase/lactonase 3 PON3 0.0141
3587 Gastrotropin FABP6 0.0137
1656 CYP2B protein CYP2B 0.0137
6167 Organic solute transporter subunit beta OSTB 0.0134
6166 Organic solute transporter subunit alpha OSTA 0.0134
696 Kappa-type opioid receptor OPRK1 0.0131
594 Thyroxine-binding globulin SERPINA7 0.013
6241 Nuclear receptor coactivator 2 NCOA2 0.013
318 Alpha-2A adrenergic receptor ADRA2A 0.013
465 Calmodulin CALM1 0.0129
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0128
140 30S ribosomal protein S9 rpsI 0.0127
6719 30S ribosomal protein S9 rpsI 0.0127
6725 30S ribosomal protein S9 rpsI 0.0127
23 D(1A) dopamine receptor DRD1 0.0126
341 5-hydroxytryptamine 3 receptor HTR3A 0.0126
705 Glutamate receptor 1 GRIA1 0.0125
241 Calcium-transporting ATPase type 2C member 1 ATP2C1 0.0123
482 Glycine receptor subunit alpha-1 GLRA1 0.0123
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0122
122 P2Y purinoceptor 12 P2RY12 0.0122
6220 Aryl hydrocarbon receptor AHR 0.0122
758 Thyroid hormone receptor alpha THRA 0.0121
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.0119
713 Sodium-dependent dopamine transporter SLC6A3 0.0119
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0119
4094 Gamma-aminobutyric acid type B receptor, subunit 2 GABBR2 0.0119
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0119
124 Histamine H2 receptor HRH2 0.0118
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0117
632 Alpha-1B adrenergic receptor ADRA1B 0.0117
537 ATP synthase delta chain, mitochondrial ATP5D 0.0117
2016 Dipeptidase 1 DPEP1 0.0115
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0113
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0112
338 DNA polymerase UL30 0.0112
379 DNA polymerase UL54 0.0112
697 DNA polymerase ORF28 0.0112
2482 DNA polymerase 43 0.0112
4104 DNA polymerase BALF5 0.0112
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0111
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.011
22 30S ribosomal protein S4 rpsD 0.0109
6714 30S ribosomal protein S4 rpsD 0.0109
346 Thyroid hormone receptor beta-1 THRB 0.0108
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0107
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0105
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0104
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0104
1 Peptidoglycan synthetase ftsI ftsI 0.0104
4155 Peptidoglycan synthetase ftsI ftsI 0.0104
844 Epidermal growth factor receptor EGFR 0.0103
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0102
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0102
629 Alpha-2B adrenergic receptor ADRA2B 0.0101
1010 Cytochrome P450 51A1 CYP51A1 0.01
558 Solute carrier family 12 member 1 SLC12A1 0.0099
2211 Fatty acid-binding protein, heart FABP3 0.0098
590 5-hydroxytryptamine 2C receptor HTR2C 0.0098
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0097
3671 7-alpha-hydroxysteroid dehydrogenase hdhA 0.0096
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0096
566 Serotransferrin TF 0.0094
6149 Solute carrier family 22 member 10 SLC22A10 0.0094
240 Gamma-aminobutyric acid type B receptor, subunit 1 GABBR1 0.0093
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0093
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0092
5934 Cytochrome P450 26A1 CYP26A1 0.0091
818 50S ribosomal protein L10 rplJ 0.009
6137 Multidrug resistance-associated protein 6 ABCC6 0.0089
633 Penicillin-binding proteins 1A/1B pbpA 0.0089
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0089
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0088
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0088
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0086
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0085
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0084
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0083
952 Dipeptidyl peptidase 4 DPP4 0.0083
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0083
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0083
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0083
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0083
6033 High affinity interleukin-8 receptor A CXCR1 0.0082
183 Vascular endothelial growth factor A VEGFA 0.0082
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0081
3957 Adenosine deaminase ADA 0.0081
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.008
780 Retinoic acid receptor RXR-gamma RXRG 0.008
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.008
6525 Group IID secretory phospholipase A2 PLA2G2D 0.008
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.008
1119 Peroxiredoxin-5, mitochondrial PRDX5 0.0079
115 Penicillin-binding protein 2 mrdA 0.0079
6069 Penicillin-binding protein 2 mrdA 0.0079
6118 Penicillin-binding protein 2 penA 0.0079
6187 Penicillin-binding protein 2 pbpA 0.0079
6686 Penicillin-binding protein 2 pbp2 0.0079
6939 Penicillin-binding protein 2 mrdA 0.0079
7163 Penicillin-binding protein 2 pbpA 0.0079
6068 Guanylate cyclase soluble subunit alpha-2 GUCY1A2 0.0079
459 Retinoic acid receptor RXR-alpha RXRA 0.0079
811 Translocator protein TSPO 0.0078
6043 Putative G-protein coupled receptor 44 GPR44 0.0078
1680 Solute carrier family 2, facilitated glucose transporter member 1 SLC2A1 0.0078
3809 Estrogen-related receptor gamma ESRRG 0.0078
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.0077
889 3-oxoacyl-[acyl-carrier-protein] synthase 1 fabB 0.0076
6860 3-oxoacyl-[acyl-carrier-protein] synthase 1 kasA 0.0076
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0075
789 Alpha-1D adrenergic receptor ADRA1D 0.0074
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0074
29 Tubulin beta-1 chain TUBB1 0.0074
174 Sigma 1-type opioid receptor SIGMAR1 0.0074
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0073
88 Retinoic acid receptor RXR-beta RXRB 0.0073
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0072
1867 Major prion protein PRNP 0.0072
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.0071
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.0071
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0071
438 Taste receptor type 1 member 2 TAS1R2 0.0071
199 Monocarboxylate transporter 8 SLC16A2 0.007
885 5-hydroxytryptamine 1B receptor HTR1B 0.0069
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0069
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0068
3932 Glutathione S-transferase A2 GSTA2 0.0068
725 5-hydroxytryptamine 1D receptor HTR1D 0.0067
4237 50S ribosomal protein L22 rplV 0.0067
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0067
5626 Nucleoside diphosphate kinase B NME2 0.0067
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0067
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.0066
6184 D-alanyl-D-alanine carboxypeptidase dacC dacC 0.0066
474 Acetylcholinesterase ACHE 0.0066
1757 Myeloperoxidase MPO 0.0066
36 Insulin receptor INSR 0.0066
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0066
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0066
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.0066
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.0066
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0066
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0065
3686 Acyl-CoA thioesterase I precursor tesA 0.0065
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0065
162 Retinoic acid receptor gamma-1 RARG 0.0063
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0063
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0063
1517 Beta-3 adrenergic receptor ADRB3 0.0062
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0062
6209 30S ribosomal protein S19 rpsS 0.0062
6712 30S ribosomal protein S19 rpsS 0.0062
6726 30S ribosomal protein S19 rpsS 0.0062
6207 30S ribosomal protein S14 rpsN 0.0062
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0061
229 Retinoic acid receptor beta RARB 0.006
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0059
1405 Thiopurine S-methyltransferase TPMT 0.0059
6151 Monocarboxylate transporter 10 SLC16A10 0.0059
4148 Serine/threonine-protein kinase mTOR MTOR 0.0059
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0059
730 Retinoic acid receptor alpha RARA 0.0059
70 Type-1 angiotensin II receptor AGTR1 0.0059
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0058
4210 Toll-like receptor 4 TLR4 0.0058
504 Mast/stem cell growth factor receptor KIT 0.0057
887 DNA gyrase subunit B gyrB 0.0057
4150 DNA gyrase subunit B gyrB 0.0057
6225 DNA gyrase subunit B gyrB 0.0057
273 Apoptosis regulator Bcl-2 BCL2 0.0057
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0056
1178 Adenosine A2a receptor ADORA2A 0.0056
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0056
638 D(3) dopamine receptor DRD3 0.0056
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0056
144 Hemoglobin subunit alpha HBA1 0.0056
3830 Calreticulin CALR 0.0056
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0055
84 Nuclear receptor 0B1 NR0B1 0.0055
1291 cAMP response element-binding protein CREB1 0.0055
1558 Transient receptor potential cation channel subfamily V member 1 TRPV1 0.0055
5294 Nucleoside diphosphate kinase A NME1 0.0055
3426 Glutamine synthetase glnA 0.0054
3987 Glutamine synthetase GLUL 0.0054
571 Melatonin receptor type 1A MTNR1A 0.0054
362 Melatonin receptor type 1B MTNR1B 0.0054
5353 Glutamate decarboxylase alpha gadA 0.0054
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0054
606 Cytochrome P450 27, mitochondrial CYP27A1 0.0054
819 Penicillin-binding protein 4 dacB 0.0053
663 Solute carrier family 12 member 4 SLC12A4 0.0053
53 Solute carrier family 12 member 5 SLC12A5 0.0053
4238 50S ribosomal protein L4 rplD 0.0053
5578 50S ribosomal protein L4 rplD 0.0053
6173 50S ribosomal protein L4 rplD 0.0053
6219 50S ribosomal protein L4 rplD 0.0053
2853 14 kDa fatty acid-binding protein Not Available 0.0053
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0053
766 Beta-2 adrenergic receptor ADRB2 0.0052
275 Arachidonate 5-lipoxygenase ALOX5 0.0051
6034 Hydroxyindole O-methyltransferase ASMT 0.0051
6035 Nuclear receptor ROR-beta RORB 0.0051
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0051
6036 Eosinophil peroxidase EPX 0.0051
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0051
7 Nitric oxide synthase, inducible NOS2 0.0051
378 Alpha-2C adrenergic receptor ADRA2C 0.0051
3760 Penicillin-binding protein 5 precursor dacA 0.005
80 Peroxisome proliferator-activated receptor alpha PPARA 0.005
6027 Alkaline phosphatase, tissue-nonspecific isozyme ALPL 0.005
310 Solute carrier family 12 member 2 SLC12A2 0.0049
1141 Sialidase-1 NEU1 0.0049
64 Neuraminidase NA 0.0049
641 Neuraminidase NA 0.0049
2676 Neuraminidase NA 0.0049
3026 Neuraminidase NA 0.0049
3519 Neuraminidase NA 0.0049
6007 Neuraminidase NA 0.0049
357 Carbonic anhydrase 2 CA2 0.0049
6182 Cytochrome P450 2J2 CYP2J2 0.0049
634 Squalene monooxygenase SQLE 0.0048
7196 Squalene monooxygenase ERG1 0.0048
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.0048
161 Tubulin beta chain TUBB 0.0048
312 Tubulin beta chain TUB2 0.0048
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0048
716 5-hydroxytryptamine 7 receptor HTR7 0.0047
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0047
284 DNA-directed RNA polymerase beta chain rpoB 0.0047
5773 DNA-directed RNA polymerase beta chain rpoB 0.0047
6002 Prostaglandin E2 receptor EP4 subtype PTGER4 0.0047
1198 Serum paraoxonase/arylesterase 1 PON1 0.0047
2183 Fatty acid-binding protein, adipocyte FABP4 0.0047
6223 Penicillin-binding protein 1C pbpC 0.0047
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0047
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0047
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0046
3382 Glycolipid transfer protein GLTP 0.0046
332 Beta-lactamase blaZ 0.0046
2478 Beta-lactamase ampC 0.0046
2613 Beta-lactamase ampC 0.0046
2635 Beta-lactamase ampC 0.0046
2700 Beta-lactamase penP 0.0046
5445 Beta-lactamase blaB 0.0046
6019 Beta-lactamase SHV-7 0.0046
6701 Beta-lactamase cphA 0.0046
856 Vitamin D3 receptor VDR 0.0046
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0045
768 FK506-binding protein 1A FKBP1A 0.0045
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0045
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0045
765 Indoleamine 2,3-dioxygenase IDO1 0.0045
2021 Thrombomodulin THBD 0.0044
2981 Phospholipase A2, membrane associated PLA2G2A 0.0044
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.0044
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0044
2178 Metabotropic glutamate receptor 5 GRM5 0.0044
4131 Prostaglandin E2 receptor, EP3 subtype PTGER3 0.0044
5645 DNA topoisomerase 4 subunit B parE 0.0044
6227 DNA topoisomerase 4 subunit B parE 0.0044
406 Prostaglandin E2 receptor, EP2 subtype PTGER2 0.0043
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0043
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0043
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0043
130 Prostacyclin synthase PTGIS 0.0043
193 Beta-1 adrenergic receptor ADRB1 0.0043
342 P protein [Includes: DNA-directed DNA polymerase P 0.0042
612 P protein [Includes: DNA-directed DNA polymerase P 0.0042
817 DNA topoisomerase 2-alpha TOP2A 0.0042
1630 Integrin beta-2 ITGB2 0.0041
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0041
3688 Branched-chain-amino-acid aminotransferase ilvE 0.0041
6102 Arylamine N-acetyltransferase 2 NAT2 0.0041
3997 Cytochrome P450 24A1, mitochondrial CYP24A1 0.0041
6508 Putative uncharacterized protein srtB 0.004
6543 Putative uncharacterized protein tcp14 0.004
6615 Putative uncharacterized protein MT0785 0.004
6623 Putative uncharacterized protein Not Available 0.004
6806 Putative uncharacterized protein AGR_C_2535 0.004
6813 Putative uncharacterized protein SAV4671 0.004
6815 Putative uncharacterized protein AFE_1514 0.004
6819 Putative uncharacterized protein RUMGNA_03254 0.004
6825 Putative uncharacterized protein CV_3270 0.004
4161 Furin FURIN 0.004
276 Sodium- and chloride-dependent GABA transporter 1 SLC6A1 0.0039
6218 Pannexin-1 PANX1 0.0039
5482 Sialidase-2 NEU2 0.0039
751 Potassium channel subfamily K member 6 KCNK6 0.0039
102 DNA topoisomerase I, mitochondrial TOP1MT 0.0039
1129 C-C chemokine receptor type 5 CCR5 0.0039
1852 Microtubule-associated protein 2 MAP2 0.0039
6501 Fatty acid-binding protein, liver FABP1 0.0038
6067 Penicillin binding protein 2a mecA 0.0038
5878 Alpha-7 nicotinic cholinergic receptor subunit CHRFAM7A 0.0038
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.0038
1992 Vitamin D-binding protein GC 0.0038
3685 Catabolite gene activator crp 0.0038
4655 Adenylate cyclase cyaC 0.0038
4759 Adenylate cyclase cyaB2 0.0038
1050 Bile salt sulfotransferase SULT2A1 0.0038
5787 Angiopoietin-1 receptor TEK 0.0037
407 Vascular endothelial growth factor receptor 2 KDR 0.0037
2472 Voltage-gated potassium channel kcsA 0.0037
6366 Voltage-gated potassium channel kcsA 0.0037
436 5-hydroxytryptamine 2B receptor HTR2B 0.0037
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0037
511 5-hydroxytryptamine 1F receptor HTR1F 0.0037
2782 Complement C1s subcomponent C1S 0.0037
228 Beta platelet-derived growth factor receptor PDGFRB 0.0037
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.0037
65 Matrix metalloproteinase-9 Not Available 0.0036
427 Substance-P receptor TACR1 0.0036
68 Cannabinoid receptor 1 CNR1 0.0036
267 Plasminogen activator inhibitor 1 SERPINE1 0.0036
172 Potassium channel subfamily K member 1 KCNK1 0.0036
185 Vasopressin V1a receptor AVPR1A 0.0035
4217 Telomerase reverse transcriptase TERT 0.0035
509 Thymidine kinase TK 0.0035
570 Thymidine kinase TK 0.0035
2559 Thymidine kinase TK 0.0035
3430 Thymidine kinase tdk 0.0035
3518 Thymidine kinase TK 0.0035
5301 Thymidine kinase tdk 0.0035
5771 Thymidine kinase ORF36 0.0035
7009 Thymidine kinase ORF36 0.0035
939 50S ribosomal protein L3 rplC 0.0035
432 D(4) dopamine receptor DRD4 0.0035
6169 ATP-binding cassette sub-family A member 5 ABCA5 0.0035
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0034
3815 Complement C1q subcomponent subunit A C1QA 0.0034
3816 Complement C1q subcomponent subunit B C1QB 0.0034
322 Vasopressin V2 receptor AVPR2 0.0034
3817 Complement C1q subcomponent subunit C C1QC 0.0034
6138 Multidrug resistance protein 3 ABCB4 0.0034
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0034
3818 Low affinity immunoglobulin gamma Fc region receptor III-A FCGR3A 0.0034
3819 Low affinity immunoglobulin gamma Fc region receptor II-a FCGR2A 0.0034
1102 Low affinity immunoglobulin gamma Fc region receptor III-B FCGR3B 0.0034
3821 Low affinity immunoglobulin gamma Fc region receptor II-c FCGR2C 0.0034
3814 Complement C1r subcomponent C1R 0.0034
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0034
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0034
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0034
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0034
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0034
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0034
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0034
3820 Low affinity immunoglobulin gamma Fc region receptor II-b FCGR2B 0.0034
471 Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) SLC6A14 0.0033
26 Vascular endothelial growth factor receptor 3 FLT4 0.0033
1618 High affinity nerve growth factor receptor NTRK1 0.0033
6042 Prostaglandin reductase 2 PTGR2 0.0033
295 Carbonic anhydrase 1 CA1 0.0033
2249 Aspartate aminotransferase aspC 0.0033
2671 Aspartate aminotransferase aspC 0.0033
5490 Aspartate aminotransferase Not Available 0.0033
6221 Steroid hormone receptor ERR1 ESRRA 0.0033
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0033
814 Ryanodine receptor 1 RYR1 0.0033
6432 Transporter snf 0.0033
4760 Mll3241 protein mll3241 0.0032
24 Thymidylate synthase TMP1 0.0032
359 Thymidylate synthase TYMS 0.0032
2626 Thymidylate synthase thyA 0.0032
2729 Thymidylate synthase thyA 0.0032
5352 Thymidylate synthase THYA 0.0032
1353 DNA topoisomerase 1 TOP1 0.0032
3552 DNA topoisomerase 1 topA 0.0032
5818 Folate receptor alpha FOLR1 0.0032
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0032
6677 Myelin P2 protein PMP2 0.0032
784 High affinity immunoglobulin gamma Fc receptor I FCGR1A 0.0032
32 Vascular endothelial growth factor receptor 1 FLT1 0.0032
592 Carbonic anhydrase 4 CA4 0.0032
921 Glutamate receptor 2 GRIA2 0.0032
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0032
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0032
595 Fibrinogen alpha chain FGA 0.0032
5923 Microtubule-associated protein tau MAPT 0.0031
5924 Microtubule-associated protein 4 MAP4 0.0031
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0031
6168 Solute carrier family 22 member 16 SLC22A16 0.0031
1792 Tissue-type plasminogen activator PLAT 0.0031
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.003
5849 cAMP-dependent protein kinase type I-alpha regulatory subunit PRKAR1A 0.003
1192 Sulfotransferase 1A1 SULT1A1 0.003
2578 Tubulin beta-3 chain TUBB3 0.003
2285 Streptogramin A acetyltransferase vatD 0.003
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.003
581 Cytochrome P450 2R1 CYP2R1 0.003
4122 Histone deacetylase 2 HDAC2 0.0029
6103 Arylamine N-acetyltransferase 1 NAT1 0.0029
3813 Fibrinogen gamma chain FGG 0.0029
3812 Fibrinogen beta chain [Contains: Fibrinopeptide B] FGB 0.0029
527 Prostacyclin receptor PTGIR 0.0029
365 Dihydrofolate reductase DHFR 0.0029
2381 Dihydrofolate reductase DFR1 0.0029
2833 Dihydrofolate reductase Not Available 0.0029
2931 Dihydrofolate reductase folA 0.0029
3544 Dihydrofolate reductase folA 0.0029
3682 Dihydrofolate reductase folA 0.0029
6642 Dihydrofolate reductase folA 0.0029
6756 Dihydrofolate reductase dfrA 0.0029
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0029
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0029
672 Prostaglandin F2-alpha receptor PTGFR 0.0028
3917 Methylenetetrahydrofolate reductase MTHFR 0.0028
233 Potassium channel subfamily K member 2 KCNK2 0.0028
293 Gamma-glutamyl hydrolase GGH 0.0028
131 Synaptic vesicular amine transporter SLC18A2 0.0028
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0028
1525 Heparin-binding growth factor 2 FGF2 0.0028
1278 Pro-epidermal growth factor EGF 0.0028
2320 Thymidine kinase, cytosolic TK1 0.0028
723 Cytosolic phospholipase A2 PLA2G4A 0.0027
976 Platelet glycoprotein IX GP9 0.0027
5126 Arginase rocF 0.0027
67 Prolyl 4-hydroxylase subunit alpha-1 P4HA1 0.0027
4173 Tyrosine-protein kinase JAK2 JAK2 0.0027
867 Penicillin-binding protein 3 pbpC 0.0027
6119 Penicillin-binding protein 3 pbp3 0.0027
7154 Penicillin-binding protein 3 pbp3 0.0027
7157 Penicillin-binding protein 3 LMHCC_2184 0.0027
7162 Penicillin-binding protein 3 pbpB 0.0027
7172 Penicillin-binding protein 3 pbp3 0.0027
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0027
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.0027
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.0027
1654 Interleukin-1 beta IL1B 0.0026
2461 D-alanyl-D-alanine carboxypeptidase Not Available 0.0026
5756 D-alanyl-D-alanine carboxypeptidase dac 0.0026
6171 Solute carrier family 28 member 3 SLC28A3 0.0026
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0026
87 Hypoxanthine-guanine phosphoribosyltransferase HPRT1 0.0026
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0026
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0026
489 Monocarboxylate transporter 2 SLC16A7 0.0026
49 Endothelin B receptor EDNRB 0.0026
1313 Lactoylglutathione lyase GLO1 0.0025
517 Alcohol dehydrogenase 1C ADH1C 0.0025
740 Argininosuccinate synthase ASS1 0.0025
865 Argininosuccinate synthase ASS1 0.0025
2680 Argininosuccinate synthase argG 0.0025
3194 Argininosuccinate synthase argG 0.0025
4252 Penicillin-binding protein 5 dacA 0.0025
1650 Heme carrier protein 1 SLC46A1 0.0025
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0025
291 Nitric-oxide synthase, endothelial NOS3 0.0025
109 Mitochondrial carnitine/acylcarnitine carrier protein CACL SLC25A29 0.0025
636 Mitochondrial carnitine/acylcarnitine carrier protein SLC25A20 0.0025
2391 Ferrochelatase hemH 0.0025
6502 Ferrochelatase DKFZp686P18130 0.0025
1591 Ferrochelatase, mitochondrial FECH 0.0025
163 D(1B) dopamine receptor DRD5 0.0024
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0024
1039 Histone deacetylase 9 HDAC9 0.0024
578 Endothelin-1 receptor EDNRA 0.0024
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0024
1507 Cytochrome c CYCS 0.0024
544 Potassium voltage-gated channel subfamily E member 1 KCNE1 0.0024
2207 Rhodopsin RHO 0.0024
1483 Membrane copper amine oxidase AOC3 0.0024
159 Penicillin-binding protein 2B penA 0.0024
6121 Penicillin-binding protein 2B penA 0.0024
6039 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A PDE11A 0.0024
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0024
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0024
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0024
6231 Pepsin A PGA3 0.0024
5852 Type-2 angiotensin II receptor AGTR2 0.0024
642 3-oxo-5-alpha-steroid 4-dehydrogenase 2 SRD5A2 0.0023
777 Tumor necrosis factor TNF 0.0023
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.0023
1262 Corticotropin-lipotropin POMC 0.0023
624 Guanidinoacetate N-methyltransferase GAMT 0.0022
3937 Fatty-acid amide hydrolase FAAH 0.0022
990 Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 0.0022
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0022
1714 Mitogen-activated protein kinase 3 MAPK3 0.0022
494 Caspase-1 CASP1 0.0022
3014 Ribonuclease UK114 HRSP12 0.0022
3718 Hydrogen peroxide-inducible genes activator oxyR 0.0022
3617 Non-heme chloroperoxidase cpo 0.0022
5426 Non-heme chloroperoxidase cpo 0.0022
5428 Replication protein repA 0.0022
5427 Hydroxyquinol 1,2-dioxygenase chqB 0.0022
259 Microsomal triglyceride transfer protein large subunit MTTP 0.0022
3018 HTH-type transcriptional regulator malT malT 0.0022
2449 Tubulin alpha-3 chain TUBA1A 0.0021
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0021
298 Renin REN 0.0021
6506 Stathmin-4 STMN4 0.0021
707 72 kDa type IV collagenase MMP2 0.0021
1256 5-hydroxytryptamine 6 receptor HTR6 0.0021
6495 Cytochrome c oxidase subunit 7C, mitochondrial COX7C 0.0021
6493 Cytochrome c oxidase subunit 6C COX6C 0.0021
6494 Cytochrome c oxidase subunit 7B, mitochondrial COX7B 0.0021
6496 Cytochrome c oxidase subunit 8A, mitochondrial COX8A 0.0021
6497 Cytochrome c oxidase subunit 6A2, mitochondrial COX6A2 0.0021
6499 Cytochrome c oxidase polypeptide 7A1, mitochondrial COX7A1 0.0021
6498 Cytochrome c oxidase subunit 6B1 COX6B1 0.0021
6491 Cytochrome c oxidase subunit 5A, mitochondrial COX5A 0.0021
6489 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial COX4I1 0.0021
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0021
5793 Cytochrome c oxidase subunit 2 MT-CO2 0.0021
6559 Cytochrome c oxidase subunit 2 ctaC 0.0021
6669 Cytochrome c oxidase subunit 2 ctaC 0.0021
6490 Cytochrome c oxidase subunit 3 MT-CO3 0.0021
371 Cytochrome c oxidase subunit 1 MT-CO1 0.0021
6558 Cytochrome c oxidase subunit 1 ctaD 0.0021
572 Integrin alpha-L ITGAL 0.0021
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0021
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0021
551 Carnitine O-acetyltransferase CRAT 0.0021
412 Peroxisomal carnitine O-octanoyltransferase CROT 0.0021
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0021
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0021
741 Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 0.0021
2539 Tubulin alpha-1 chain TUBA4A 0.0021
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0021
331 Retinol-binding protein I, cellular RBP1 0.0021
1768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit GNG2 0.0021
1268 Neuropeptide S receptor NPSR1 0.002
1571 G protein-activated inward rectifier potassium channel 1 KCNJ3 0.002
94 5-hydroxytryptamine 4 receptor HTR4 0.002
1581 G protein-activated inward rectifier potassium channel 2 KCNJ6 0.002
750 Voltage-dependent calcium channel gamma-1 subunit CACNG1 0.002
4199 Sphingosine 1-phosphate receptor Edg-8 S1PR5 0.002
2540 Choloylglycine hydrolase cbh 0.0019
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0019
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.0019
2499 Tubulin beta-2C chain TUBB2C 0.0019
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.0019
2958 Probable tautomerase ydcE pptA 0.0019
2573 Cocaine esterase cocE 0.0019
7263 Cocaine esterase Not Available 0.0019
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0019
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0019
477 DNA topoisomerase 4 subunit A parC 0.0019
886 DNA topoisomerase 4 subunit A parC 0.0019
6226 DNA topoisomerase 4 subunit A parC 0.0019
3115 Ras-related protein Rab-9 RAB9A 0.0019
6073 Potassium channel subfamily K member 9 KCNK9 0.0018
6072 Potassium channel subfamily K member 3 KCNK3 0.0018
3603 Chlorocatechol 1,2-dioxygenase clcA 0.0018
404 DNA gyrase subunit A gyrA 0.0018
6224 DNA gyrase subunit A gyrA 0.0018
2077 Caspase-3 CASP3 0.0018
5998 Toll-like receptor 8 TLR8 0.0018
319 Opioid receptor, sigma 1 OPRS1 0.0018
712 Tubulin alpha chain TUB1 0.0018
1968 ATP-sensitive inward rectifier potassium channel 12 KCNJ12 0.0018
565 Extracellular calcium-sensing receptor CASR 0.0018
3312 Fatty acid-binding protein, brain FABP7 0.0018
683 Potassium transporter GK0582 0.0018
613 Atrial natriuretic peptide receptor A NPR1 0.0017
621 Periplasmic [Fe] hydrogenase 1 Not Available 0.0017
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0017
5432 Trafficking protein particle complex subunit 3 TRAPPC3 0.0017
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0017
165 FL cytokine receptor FLT3 0.0017
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0016
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0016
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0016
5682 Ribonuclease pancreatic RNASE1 0.0016
2300 Lysozyme E 0.0016
3633 Lysozyme R 0.0016
5597 Lysozyme 17 0.0016
6100 BDNF/NT-3 growth factors receptor NTRK2 0.0016
3616 Fatty acid-binding protein, epidermal FABP5 0.0016
5431 Lipid binding protein Not Available 0.0016
5433 UPF0230 protein TM_1468 TM_1468 0.0016
5430 Hepatocyte nuclear factor 4-gamma HNF4G 0.0016
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0016
528 5-hydroxytryptamine 1E receptor HTR1E 0.0016
173 Toll-like receptor 7 TLR7 0.0016
3233 Bile acid receptor NR1H4 0.0015
251 Alcohol dehydrogenase 1A ADH1A 0.0015
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.0015
6500 Phospholipase A2 PLA2G1B 0.0015
1629 Transcription factor AP-1 JUN 0.0015
719 Retinoic acid receptor responder protein 1 RARRES1 0.0014
770 Retinoic acid-induced protein 3 GPRC5A 0.0014
1541 Metalloproteinase mmp20 0.0014
820 Glycine receptor subunit alpha-2 GLRA2 0.0014
2693 Heat-labile enterotoxin B chain eltB 0.0014
4674 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase cumD 0.0014
6645 D-amino-acid oxidase DAO 0.0014
6032 PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) fas 0.0014
444 Alcohol dehydrogenase 1B ADH1B 0.0014
896 Glutathione S-transferase Mu 1 GSTM1 0.0014
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0014
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0014
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0014
936 Ephrin type-A receptor 2 EPHA2 0.0013
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0013
283 SEC14-like protein 2 SEC14L2 0.0013
5798 Mitogen-activated protein kinase 11 MAPK11 0.0013
605 Fumarate reductase flavoprotein subunit frdA 0.0013
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0013
3673 Fumarate reductase flavoprotein subunit fccA 0.0013
4912 Fumarate reductase flavoprotein subunit ifcA 0.0013
6549 Fumarate reductase flavoprotein subunit frdA 0.0013
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.0013
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.0013
6459 Glycodelin PAEP 0.0013
4010 Mitochondrial dicarboxylate carrier SLC25A10 0.0013
1410 Oxidoreductase HSD17B6 0.0013
4725 Oxidoreductase Not Available 0.0013
5124 Oxidoreductase Not Available 0.0013
4007 Succinate receptor 1 SUCNR1 0.0013
4008 Succinyl-CoA:3-ketoacid-coenzyme A transferase 2, mitochondrial OXCT2 0.0013
4002 Succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial SUCLG1 0.0013
673 Solute carrier family 13 member 3 SLC13A3 0.0013
391 Succinyl-CoA ligase [GDP-forming] beta-chain, mitochondrial SUCLG2 0.0013
4009 Succinyl-CoA ligase [ADP-forming] beta-chain, mitochondrial SUCLA2 0.0013
498 Solute carrier family 13 member 2 SLC13A2 0.0013
25 Solute carrier family 13 member 1 SLC13A1 0.0013
569 Retinal dehydrogenase 2 ALDH1A2 0.0013
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0013
6116 Gastric triacylglycerol lipase LIPF 0.0012
823 Fibroblast growth factor receptor 2 FGFR2 0.0012
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.0012
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0012
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0012
822 Aldose reductase AKR1B1 0.0012
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0012
16 Adenosine A1 receptor ADORA1 0.0012
3806 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A 0.0012
3823 Cytokine receptor common gamma chain IL2RG 0.0012
85 Growth hormone receptor GHR 0.0012
6126 Carbonic anhydrase 7 CA7 0.0012
2107 Microtubule-associated protein 1A MAP1A 0.0012
1864 RET proto-oncogene RET 0.0012
611 Retinal dehydrogenase 1 ALDH1A1 0.0012
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0012
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0012
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0012
1295 Fatty acid synthase FASN 0.0012
4226 Uridine phosphorylase 2 UPP2 0.0012
4003 Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial OXCT1 0.0012
239 Coagulation factor X F10 0.0011
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0011
754 Pancreatic triacylglycerol lipase PNLIP 0.0011
4225 Uridine phosphorylase 1 UPP1 0.0011
4000 Prolyl 4-hydroxylase subunit alpha-2 P4HA2 0.0011
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0011
585 Aspartyl/asparaginyl beta-hydroxylase ASPH 0.0011
6146 High affinity copper uptake protein 1 SLC31A1 0.0011
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0011
3940 Gamma-butyrobetaine dioxygenase BBOX1 0.0011
97 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 PLOD1 0.0011
3938 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 PLOD3 0.0011
3964 Trimethyllysine dioxygenase, mitochondrial TMLHE 0.0011
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0011
4006 Succinate dehydrogenase cytochrome b560 subunit, mitochondrial SDHC 0.0011
4001 Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial SDHB 0.0011
1360 Sphingomyelin phosphodiesterase SMPD1 0.0011
724 Interleukin-2 receptor alpha chain IL2RA 0.0011
717 Interleukin-2 receptor subunit beta IL2RB 0.0011
518 Peroxidase/catalase T katG 0.0011
54 Prothrombin F2 0.001
1810 Protein S100-A1 S100A1 0.001
6097 Protein S100-A2 S100A2 0.001
4203 Histamine N-methyltransferase HNMT 0.001
4228 Keratin, type II cytoskeletal 7 KRT7 0.001
413 Amidophosphoribosyltransferase PPAT 0.001
2515 Amidophosphoribosyltransferase purF 0.001
3714 Amidophosphoribosyltransferase purF 0.001
1144 Hepatocyte growth factor receptor MET 0.001
3949 Prolyl 3-hydroxylase 2 LEPREL1 0.001
3945 Prolyl 3-hydroxylase 1 LEPRE1 0.001
3951 Prolyl 3-hydroxylase 3 LEPREL2 0.001
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.001
493 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 0.001
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.001
3999 Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial SDHD 0.001
512 DNA-directed RNA polymerase alpha chain rpoA 0.001
5772 DNA-directed RNA polymerase alpha chain rpoA 0.001
5300 Antigen peptide transporter 1 TAP1 0.001
4041 Microsomal glutathione S-transferase 2 MGST2 0.001
197 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial SDHA 0.001
6824 Tyrosine-protein kinase Lyn LYN 0.001
908 Glutathione S-transferase theta-1 GSTT1 0.001
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0009
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0009
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0009
2268 Cholesterol oxidase choB 0.0009
2822 Cholesterol oxidase choA 0.0009
4773 Deoxycytidine kinase DCK 0.0009
2298 Cytochrome P450-cam camC 0.0009
6105 3-oxo-5-beta-steroid 4-dehydrogenase AKR1D1 0.0009
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0009
3086 Plasmepsin-2 Not Available 0.0009
76 Nitric-oxide synthase, brain NOS1 0.0009
1048 Protein S100-A13 S100A13 0.0009
2226 Protein S100-A12 S100A12 0.0009
1759 85 kDa calcium-independent phospholipase A2 PLA2G6 0.0009
1770 Phospholipase C PLCL1 0.0009
2841 Phospholipase C plc 0.0009
1648 Elastin ELN 0.0009
6131 Carbonic anhydrase 14 CA14 0.0009
2283 Steroid Delta-isomerase ksi 0.0009
2920 Steroid Delta-isomerase ksi 0.0009
153 Dopamine beta-hydroxylase DBH 0.0009
208 DNA-directed RNA polymerase beta' chain rpoC 0.0009
5774 DNA-directed RNA polymerase beta' chain rpoC 0.0009
390 Adenosine A3 receptor ADORA3 0.0009
2132 Protein S100-B S100B 0.0009
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0008
3404 Exotoxin A eta 0.0008
3639 Thymidine phosphorylase deoA 0.0008
3936 Thymidine phosphorylase TYMP 0.0008
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0008
6122 Carbonic anhydrase 3 CA3 0.0008
2325 Sulfotransferase family cytosolic 2B member 1 SULT2B1 0.0008
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0008
2232 Interleukin-5 IL5 0.0008
1593 Mucin-2 MUC2 0.0008
4031 Glutathione S-transferase A1 GSTA1 0.0008
6163 Copper-transporting ATPase 2 ATP7B 0.0008
6165 Copper-transporting ATPase 1 ATP7A 0.0008
1025 Aquaporin-1 AQP1 0.0008
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0008
3856 Fibroblast growth factor receptor 3 FGFR3 0.0008
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0008
2091 Endoplasmin HSP90B1 0.0008
6893 Calcium/calmodulin-dependent protein kinase type II gamma chain CAMK2G 0.0007
473 L-lactate dehydrogenase A chain LDHA 0.0007
461 Glycine receptor subunit alpha-3 GLRA3 0.0007
620 Bifunctional dihydrofolate reductase-thymidylate synthase Not Available 0.0007
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0007
4954 Soluble cytochrome b558 Not Available 0.0007
4943 Cytochrome c6 petJ 0.0007
4916 Cyanoglobin glbN 0.0007
4925 Cytochrome c-type protein SHP shp 0.0007
4994 Hemoglobin-like protein HbO glbO 0.0007
4984 Neuroglobin NGB 0.0007
4947 Bacterial hemoglobin vhb 0.0007
4915 Cytochrome c-550 psbV 0.0007
4959 Cytochrome c-550 psbV 0.0007
5216 Cytochrome c-550 psbV 0.0007
4975 Cytochrome c-556 RPA3973 0.0007
4981 Iron-starvation protein PigA pigA 0.0007
5000 HemO hemO 0.0007
4942 Diheme cytochrome c napB napB 0.0007
3116 Bacterioferritin bfr 0.0007
4906 Bacterioferritin bfr 0.0007
4965 Bacterioferritin bfr 0.0007
4934 Cytochrome c-551 nirM 0.0007
5218 Cytochrome c-551 nirM 0.0007
4905 Cytochrome c2 Not Available 0.0007
4939 Cytochrome c2 cycA 0.0007
4964 Cytochrome c2 cycA 0.0007
4979 Cytochrome c2 cycA 0.0007
6673 Cytochrome c2 cycA 0.0007
4910 Cytoglobin CYGB 0.0007
4936 Cytochrome c2 iso-2 Not Available 0.0007
4935 Cytochrome c-554 cycA1 0.0007
4909 CooA protein cooA 0.0007
4998 Hemoglobin-like protein yjbI yjbI 0.0007
4961 Hemophore HasA hasA 0.0007
4907 Cytochrome c-L moxG 0.0007
6865 Cytochrome c-L moxG 0.0007
644 Heme oxygenase 2 HMOX2 0.0007
4982 Heme oxygenase 2 pbsA2 0.0007
4971 Nonaheme cytochrome c hmcA 0.0007
4931 Cytochrome P450 167A1 CYP167A1 0.0007
4904 Cytochrome c family protein GSU1996 0.0007
4976 Apocytochrome f petA 0.0007
6407 Apocytochrome f petA 0.0007
4972 P450cin cinA 0.0007
4903 Methyl-accepting chemotaxis protein Tar4 0.0007
4937 Cytochrome oxidase subunit II rcoxA 0.0007
4960 Putative cytochrome P450-family protein SCO7417 0.0007
4764 Cytochrome P450 165C4 CYP165C4 0.0007
4989 Cytochrome c551 peroxidase ccp 0.0007
5222 Cytochrome c551 peroxidase ccpA 0.0007
4999 Cytochrome P450 165B3 CYP165B3 0.0007
4926 Heme-based aerotactic transducer hemAT hemAT 0.0007
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0007
4993 Hydroxylamine oxidoreductase hao1 0.0007
4922 Cytochrome c, putative SO_4144 0.0007
4952 Catalase/peroxidase katA 0.0007
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0007
3093 Catalase HPII katE 0.0007
2112 Toll-like receptor 9 TLR9 0.0007
2290 ADP-ribosyl cyclase 2 BST1 0.0007
1830 5'-nucleotidase NT5E 0.0007
164 Histamine H4 receptor HRH4 0.0007
125 DNA polymerase beta POLB 0.0007
4311 tRNA TRDMT1 0.0007
4325 tRNA trmD 0.0007
4328 tRNA trmD 0.0007
1123 Eosinophil cationic protein RNASE3 0.0007
2599 Tyrosine-protein kinase HCK HCK 0.0007
106 Cannabinoid receptor 2 CNR2 0.0006
6174 50S ribosomal protein L32 rpmF 0.0006
215 Sodium channel protein type 11 subunit alpha SCN11A 0.0006
1196 Complement decay-accelerating factor CD55 0.0006
890 Niemann-Pick C1-like protein 1 NPC1L1 0.0006
3126 Poly [ADP-ribose] polymerase 1 PARP1 0.0006
4192 DNA topoisomerase 2-beta TOP2B 0.0006
3611 Cytidine deaminase cdd 0.0006
3707 Cytidine deaminase cdd 0.0006
4211 Cytidine deaminase CDA 0.0006
1569 G1/S-specific cyclin-D1 CCND1 0.0006
2808 Chloramphenicol acetyltransferase 3 cat3 0.0005
1341 Histamine H3 receptor HRH3 0.0005
1760 Aminopeptidase N ANPEP 0.0005
6843 Aminopeptidase N pepN 0.0005
4920 Peroxidase/catalase katG 0.0005
117 Sterol O-acyltransferase 1 SOAT1 0.0005
6743 Non-fluorescent flavoprotein luxF 0.0005
4948 Cytochrome c-553 Not Available 0.0005
6753 Apolipoprotein M APOM 0.0005
4923 Cytochrome c3 DvMF_2499 0.0005
4945 Cytochrome c3 Not Available 0.0005
4949 Cytochrome c3 DVU_3171 0.0005
4968 Cytochrome c3 cytc3 0.0005
4997 Cytochrome c3 SO_2727 0.0005
5219 Cytochrome c3 cyd 0.0005
2528 Fatty acid metabolism regulator protein fadR 0.0005
6740 Fatty acid metabolism regulator protein fadR 0.0005
6752 Guanylyl cyclase-activating protein 1 GUCA1A 0.0005
2119 Cytochrome b5 CYB5A 0.0005
394 Calcineurin subunit B isoform 1 PPP3R1 0.0005
6742 Recoverin RCVRN 0.0005
4902 Nine-heme cytochrome c Ddes_2038 0.0005
6747 Chalcone/stilbene synthase family protein MT1417 0.0005
6741 Peroxisomal 3,2-trans-enoyl-CoA isomerase PECI 0.0005
6522 Hepatocyte nuclear factor 4-alpha HNF4A 0.0005
3189 High-molecular-weight cytochrome c hmcA 0.0005
6751 Gag polyprotein gag 0.0005
6746 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform PPP3CA 0.0005
4990 PpcA ppcA 0.0005
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0005
6749 Polyprotein Not Available 0.0005
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0005
3375 Acidic cytochrome c3 Not Available 0.0005
4988 Sulfite oxidase, mitochondrial SUOX 0.0005
2915 Sensor protein fixL fixL 0.0005
4944 Sensor protein fixL fixL 0.0005
3570 Cytochrome P450 152A1 cypC 0.0005
4037 Hypothetical protein GPX1 0.0005
4297 Hypothetical protein SP_1951 0.0005
4521 Hypothetical protein BC_2969 0.0005
4540 Hypothetical protein TM_1070 0.0005
4555 Hypothetical protein MT1739 0.0005
4569 Hypothetical protein mshD 0.0005
4578 Hypothetical protein PA3270 0.0005
4747 Hypothetical protein PA3967 0.0005
5177 Hypothetical protein TM_0096 0.0005
5194 Hypothetical protein PA1204 0.0005
5240 Hypothetical protein Rv2991 0.0005
5370 Hypothetical protein TM_1158 0.0005
5710 Hypothetical protein Tb927.5.1360 0.0005
4813 Heme oxygenase hmuO 0.0005
5769 Heme oxygenase Not Available 0.0005
4385 Cytochrome c' Not Available 0.0005
4967 Cytochrome c' cycA 0.0005
5038 Cytochrome c' Not Available 0.0005
5223 Cytochrome c' cycP 0.0005
4289 Cytochrome P450 TT_P0059 0.0005
6262 Cytochrome P450 staP 0.0005
4992 Cytochrome c peroxidase Not Available 0.0005
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.0005
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.0005
6211 Tubulin epsilon chain TUBE1 0.0005
6212 Tubulin gamma-1 chain TUBG1 0.0005
6210 Tubulin delta chain TUBD1 0.0005
2230 Catalase CAT 0.0005
3249 Catalase katA 0.0005
3625 Catalase katA 0.0005
4539 Catalase katA 0.0005
4941 Catalase katB 0.0005
2417 Chloramphenicol acetyltransferase cat 0.0005
3278 Chloramphenicol acetyltransferase cat 0.0005
2810 Dr hemagglutinin structural subunit draA 0.0005
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0005
3601 Dihydropteroate synthase 1 folP1 0.0005
3807 Dihydropteroate synthase 1 folP1 0.0005
3808 Dihydropteroate synthase 2 folP2 0.0005
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0005
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0005
5961 Insulin INS 0.0005
2236 Casein kinase II subunit alpha CSNK2A1 0.0005
3411 Cytochrome P450 121 cyp121 0.0005
3670 Soluble cytochrome b562 precursor cybC 0.0005
6527 Lymphocyte antigen 96 LY96 0.0005
3913 Glutamic acid decarboxylase GAD65 0.0005
3291 Cytochrome c-552 cycA 0.0005
4927 Cytochrome c-552 nrfA 0.0005
4938 Cytochrome c-552 cycA 0.0005
4953 Cytochrome c-552 nrfA 0.0005
5217 Cytochrome c-552 cycM 0.0005
2617 Nitric oxide synthase oxygenase nos 0.0005
2701 Nitric oxide synthase oxygenase nos 0.0005
6755 Poliovirus receptor PVR 0.0005
4386 Hemoglobin-like protein HbN glbN 0.0004
3102 Flavohemoprotein hmp 0.0004
4969 Flavohemoprotein hmp 0.0004
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0004
476 RAC-alpha serine/threonine-protein kinase AKT1 0.0004
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0004
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0004
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0004
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0004
6750 ADP-ribosylation factor 6 ARF6 0.0004
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0004
6524 Protein tonB tonB 0.0004
3127 Nitrite reductase nirS 0.0004
3284 Nitrite reductase nirS 0.0004
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0004
4103 Proteasome subunit beta type 2 PSMB2 0.0004
4101 Proteasome subunit beta type 1 PSMB1 0.0004
4102 Proteasome subunit beta type 5 PSMB5 0.0004
3221 Cytochrome c4 cc4 0.0004
2972 6-deoxyerythronolide B hydroxylase eryF 0.0004
1374 Natriuretic peptides B NPPB 0.0004
1827 Gap junction alpha-1 protein GJA1 0.0004
1908 Vascular cell adhesion protein 1 VCAM1 0.0004
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0004
935 Proto-oncogene tyrosine-protein kinase Yes YES1 0.0004
1063 Signal transducer and activator of transcription 5B STAT5B 0.0004
2616 Ganglioside GM2 activator GM2A 0.0004
2216 Fibroblast growth factor receptor 4 FGFR4 0.0004
4608 Putative cytochrome P450 SCO1207 0.0004
4963 Putative cytochrome P450 SCO2884 0.0004
6254 Putative cytochrome P450 SCO6998 0.0004
2435 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0004
6613 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0004
735 Alanine aminotransferase 1 GPT 0.0004
3904 Alanine aminotransferase 2 GPT2 0.0004
1176 Mitogen-activated protein kinase 1 MAPK1 0.0004
2297 Genome polyprotein Not Available 0.0004
2322 Genome polyprotein Not Available 0.0004
2694 Genome polyprotein Not Available 0.0004
2719 Genome polyprotein Not Available 0.0004
2860 Genome polyprotein Not Available 0.0004
2928 Genome polyprotein Not Available 0.0004
3160 Genome polyprotein Not Available 0.0004
3260 Genome polyprotein Not Available 0.0004
4783 Genome polyprotein Not Available 0.0004
5726 Genome polyprotein Not Available 0.0004
5779 Genome polyprotein Not Available 0.0004
5867 Genome polyprotein Not Available 0.0004
6253 Genome polyprotein Not Available 0.0004
6301 Genome polyprotein Not Available 0.0004
6380 Genome polyprotein Not Available 0.0004
6381 Genome polyprotein Not Available 0.0004
6437 Genome polyprotein Not Available 0.0004
6520 Genome polyprotein Not Available 0.0004
6521 Genome polyprotein Not Available 0.0004
6652 Genome polyprotein Not Available 0.0004
6734 Genome polyprotein Not Available 0.0004
6735 Genome polyprotein Not Available 0.0004
6736 Genome polyprotein Not Available 0.0004
6737 Genome polyprotein Not Available 0.0004
6738 Genome polyprotein Not Available 0.0004
6739 Genome polyprotein Not Available 0.0004
6744 Genome polyprotein Not Available 0.0004
6748 Genome polyprotein Not Available 0.0004
6894 Genome polyprotein Not Available 0.0004
6898 Genome polyprotein Not Available 0.0004
358 Cystathionine beta-synthase CBS 0.0004
6316 ADP-ribosylation factor 1 ARF1 0.0004
6048 Troponin C, skeletal muscle TNNC2 0.0004
934 Proto-oncogene tyrosine-protein kinase Fyn FYN 0.0004
693 Hemoglobin subunit beta HBB 0.0003
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0003
864 Gag-Pol polyprotein gag-pol 0.0003
2237 Gag-Pol polyprotein gag-pol 0.0003
2326 Gag-Pol polyprotein gag-pol 0.0003
2451 Gag-Pol polyprotein gag-pol 0.0003
2901 Gag-Pol polyprotein gag-pol 0.0003
3165 Gag-Pol polyprotein gag-pol 0.0003
3722 Gag-Pol polyprotein gag-pol 0.0003
6306 Gag-Pol polyprotein gag-pol 0.0003
6624 Gag-Pol polyprotein gag-pol 0.0003
268 Adenosine A2b receptor ADORA2B 0.0003
828 Phenylalanine-4-hydroxylase PAH 0.0003
3109 Phenylalanine-4-hydroxylase phhA 0.0003
6268 Hydroxyacid oxidase 1 HAO1 0.0003
484 Tyrosine-protein kinase ABL2 ABL2 0.0003
2240 Cell division protein kinase 2 CDK2 0.0003
810 Heme oxygenase 1 HMOX1 0.0003
3391 Heme oxygenase 1 pbsA1 0.0003
2427 Ferrichrome-iron receptor fhuA 0.0003
6228 Nuclear receptor coactivator 1 NCOA1 0.0003
1275 Estrogen sulfotransferase SULT1E1 0.0003
760 Fibroblast growth factor 1 FGF1 0.0003
6264 cAMP-dependent protein kinase inhibitor alpha PKIA 0.0003
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.0003
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0003
6135 Sodium channel subunit beta-4 SCN4B 0.0002
6134 Sodium channel subunit beta-3 SCN3B 0.0002
6132 Sodium channel subunit beta-1 SCN1B 0.0002
6127 Carbonic anhydrase-related protein CA8 0.0002
6128 Carbonic anhydrase-related protein 10 CA10 0.0002
6133 Sodium channel subunit beta-2 SCN2B 0.0002
6129 Carbonic anhydrase-related protein 11 CA11 0.0002
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.0002
6130 Carbonic anhydrase 13 CA13 0.0002
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0002
3007 Carbonic anhydrase 12 CA12 0.0002
4205 Carbonic anhydrase 9 CA9 0.0002
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0001
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