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Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial


Partner ID 197
Name Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Synonyms 581
Gene name SDHA
General function Energy production and conversion
Specific function Not Available
Gene sequence + ...

ATGTCGGGGGTCCGGGGCCTGTCGCGGCTGCTGAGCGCTCGGCGCCTGGCGCTGGCCAAGGCGTGGCCAACAGTGTTGCAAACAGGAACCCGAGGTTTTCACTTCACTGTTGATGGGAACAAGAGGGCATCTGCTAAAGTTTCAGATTCCATTTCTGCTCAGTATCCAGTAGTGGATCATGAATTTGATGCAGTGGTGGTAGGCGCTGGAGGGGCAGGCTTGCGAGCTGCATTTGGCCTTTCTGAGGCAGGGTTTAATACAGCATGTGTTACCAAGCTGTTTCCTACCAGGTCACACACTGTTGCAGCACAGGGAGGAATCAATGCTGCTCTGGGGAACATGGAGGAGGACAACTGGAGGTGGCATTTCTACGACACCGTGAAGGGCTCCGACTGGCTGGGGGACCAGGATGCCATCCACTACATGACGGAGCAGGCCCCCGCCGCCGTGGTCGAGCTAGAAAATTATGGCATGCCGTTTAGCAGAACTGAAGATGGGAAGATTTATCAGCGTGCATTTGGTGGACAGAGCCTCAAGTTTGGAAAGGGCGGGCAGGCCCATCGGTGCTGCTGTGTGGCTGATCGGACTGGCCACTCGCTATTGCACACCTTATATGGACGGTCTCTGCGATATGATACCAGCTATTTTGTGGAGTATTTTGCCTTGGATCTCCTGATGGAGAACGGGGAGTGCCGTGGTGTCATCGCACTGTGCATAGAGGACGGGTCCATCCATCGCATAAGAGCAAAGAACACTGTTGTTGCCACAGGAGGCTACGGGCGCACCTACTTCAGCTGCACGTCTGCCCACACCAGCACTGGCGACGGCACGGCCATGATCACCAGGGCAGGCCTTCCTTGCCAGGACCTAGAGTTTGTTCAGTTCCACCCTACAGGCATATATGGTGCTGGTTGTCTCATTACGGAAGGATGTCGTGGAGAGGGAGGCATTCTCATTAACAGTCAAGGCGAAAGGTTTATGGAGCGATACGCCCCTGTCGCGAAGGACCTGGCGTCTAGAGATGTGGTGTCTCGGTCCATGACTCTGGAGATCCGAGAAGGAAGAGGCTGTGGCCCTGAGAAAGATCACGTCTACCTGCAGCTGCACCACCTACCTCCAGAGCAGCTGGCCACGCGCCTGCCTGGCATTTCAGAGACAGCCATGATCTTCGCTGGCGTGGACGTCACGAAGGAGCCGATCCCTGTCCTCCCCACCGTGCATTATAACATGGGCGGCATTCCCACCAACTACAAGGGGCAGGTCCTGAGGCACGTGAATGGCCAGGATCAGATTGTGCCCGGCCTGTACGCCTGTGGGGAGGCCGCCTGTGCCTCGGTACATGGTGCCAACCGCCTCGGGGCAAACTCGCTCTTGGACCTGGTTGTCTTTGGTCGGGCATGTGCCCTGAGCATCGAAGAGTCATGCAGGCCTGGAGATAAAGTCCCTCCAATTAAACCAAACGCTGGGGAAGAATCTGTCATGAATCTTGACAAATTGAGATTTGCTGATGGAAGCATAAGAACATCGGAACTGCGACTCAGCATGCAGAAGTCAATGCAAAATCATGCTGCCGTGTTCCGTGTGGGAAGCGTGTTGCAAGAAGGTTGTGGGAAAATCAGCAAGCTCTATGGAGACCTAAAGCACCTGAAGACGTTCGACCGGGGAATGGTCTGGAACACGGACCTGGTGGAGACCCTGGAGCTGCAGAACCTGATGCTGTGTGCGCTGCAGACCATCTACGGAGCAGAGGCACGGAAGGAGTCACGGGGCGCGCATGCCAGGGAAGACTACAAGGTGCGGATTGATGAGTACGATTACTCCAAGCCCATCCAGGGGCAACAGAAGAAGCCCTTTGAGGAGCACTGGAGGAAGCACACCCTGTCCTATGTGGACGTTGGCACTGGGAAGGTCACTCTGGAATATAGACCCGTGATCGACAAAACTTTGAACGAGGCTGACTGTGCCACCGTCCCGCCAGCCATTCGCTCCTACTGA
Protein sequence + ...

MSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIEESCRPGDKVPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQNHAAVFRVGSVLQEGCGKISKLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVRIDEYDYSKPIQGQQKKPFEEHWRKHTLSYVDVGTGKVTLEYRPVIDKTLNEADCATVPPAIRSY
GO Classification
function
purine nucleotide binding
adenyl nucleotide binding
FAD binding
binding
nucleotide binding
oxidoreductase activity, acting on the CH-CH group of donors
catalytic activity
oxidoreductase activity
process
electron transport
energy derivation by oxidation of organic compounds
main pathways of carbohydrate metabolism
physiological process
tricarboxylic acid cycle
metabolism
cellular metabolism
generation of precursor metabolites and energy
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB00139 Succinic acid
DB04141 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
DB04657 Carboxin
DB04795 Thenoyltrifluoroacetone
DB08689 UBIQUINONE-1

Associated as Prediction

Id Name
DB00126 Vitamin C
DB00128 L-Aspartic Acid
DB00139 Succinic acid
DB00157 NADH
DB00168 Aspartame
DB00172 L-Proline
DB00175 Pravastatin
DB00181 Baclofen
DB00198 Oseltamivir
DB00254 Doxycycline
DB00279 Liothyronine
DB00286 Conjugated Estrogens
DB00300 Tenofovir
DB00313 Valproic Acid
DB00328 Indomethacin
DB00345 Aminohippurate
DB00390 Digoxin
DB00437 Allopurinol
DB00456 Cefalotin
DB00469 Tenoxicam
DB00493 Cefotaxime
DB00495 Zidovudine
DB00501 Cimetidine
DB00519 Trandolapril
DB00534 Chlormerodrin
DB00536 Guanidine
DB00554 Piroxicam
DB00563 Methotrexate
DB00567 Cephalexin
DB00577 Valaciclovir
DB00583 L-Carnitine
DB00584 Enalapril
DB00586 Diclofenac
DB00595 Oxytetracycline
DB00624 Testosterone
DB00675 Tamoxifen
DB00688 Mycophenolate mofetil
DB00695 Furosemide
DB00718 Adefovir Dipivoxil
DB00756 Hexachlorophene
DB00758 Clopidogrel
DB00759 Tetracycline
DB00762 Irinotecan
DB00783 Estradiol
DB00787 Acyclovir
DB00812 Phenylbutazone
DB00863 Ranitidine
DB00887 Bumetanide
DB00908 Quinidine
DB00917 Dinoprostone
DB00927 Famotidine
DB00936 Salicyclic acid
DB01004 Ganciclovir
DB01009 Ketoprofen
DB01017 Minocycline
DB01032 Probenecid
DB01033 Mercaptopurine
DB01050 Ibuprofen
DB01051 Novobiocin
DB01053 Penicillin G
DB01065 Melatonin
DB01086 Benzocaine
DB01092 Ouabain
DB01101 Capecitabine
DB01140 Cefadroxil
DB01160 Dinoprost Tromethamine
DB01212 Ceftriaxone
DB01275 Hydralazine
DB01326 Cefamandole
DB01327 Cefazolin
DB01329 Cefoperazone
DB01410 Ciclesonide
DB01414 Cefacetrile
DB01583 Liotrix
DB01597 Cilastatin
DB01599 Probucol
DB01650 trans-2-hydroxycinnamic acid
DB02161 Hydroxy-Phenyl-Acetic Acid 8-Methyl-8-Aza-Bicyclo[3.2.1]Oct-3-Yl Ester
DB02196 Uridine-Diphosphate-N-Acetylgalactosamine
DB02527 Cyclic Adenosine Monophosphate
DB02659 Cholic Acid
DB02731 Thimerosal
DB02944 Alpha-D-Mannose
DB03056 4-Piperidino-Piperidine
DB03435 Uridine-5'-Diphosphate
DB03501 Uridine Diphosphate Galactose
DB03553 Glutaric Acid
DB03721 O-Sialic Acid
DB03772 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,5-Diol
DB03793 Benzoic Acid
DB03902 Oxalic Acid
DB04133 Degraded Cephaloridine
DB04141 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
DB04147 Lauryl Dimethylamine-N-Oxide
DB04348 Taurocholic Acid
DB04464 N-Formylmethionine
DB04509 N-Methylnaloxonium
DB04519 Caprylic acid
DB04657 Carboxin
DB04678 H TYPE II TRISACCHARIDE
DB04679 H TYPE I TRISACCHARIDE
DB04680 GALACTOSE GREASE
DB04681 BETA-METHYLLACTOSIDE
DB04741 Myxothiazol
DB04795 Thenoyltrifluoroacetone
DB04799 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole
DB04838 Cyclandelate
DB06201 Rufinamide
DB06335 Saxagliptin
DB06693 Mevastatin
DB06695 Dabigatran etexilate
DB06710 Methyltestosterone
DB07341 octyl 3-amino-3-deoxy-2-O-(2,6-dideoxy-alpha-L-lyxo-hexopyranosyl)-beta-D-galactopyranoside
DB07357 4-AMINO-2-HEXYLOXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,5-DIOL
DB07378 4-AMINO-2-OCTYLOXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,5-DIOL
DB07392 2-CHLORO-4-ISOPROPYLAMINO-6-ETHYLAMINO -1,3,5-TRIAZINE
DB07401 METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE
DB07551 2-CHLORO-4-ETHYLAMINO-6-(S(-)-2'-CYANO-4-BUTYLAMINO)-1,3,5-TRIAZINE
DB07552 2-CHLORO-4-ETHYLAMINO-6-(R(+)-2'-CYANO-4-BUTYLAMINO)-1,3,5-TRIAZINE
DB07633 octyl 3-deoxy-2-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-xylo-hexopyranoside
DB07636 5-HEPTYL-6-HYDROXY-1,3-BENZOTHIAZOLE-4,7-DIONE
DB07763 (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE
DB07778 FAMOXADONE
DB07821 (1R)-1,2,2-TRIMETHYLPROPYL (R)-METHYLPHOSPHINATE
DB08215 2-T-BUTYLAMINO-4-ETHYLAMINO-6-METHYLTHIO-S-TRIAZINE
DB08224 (1S,7S,8S,8AR)-1,2,3,7,8,8A-HEXAHYDRO-7-METHYL-8-[2-[(2R,4R)-TETRAHYDRO-4-HY DROXY-6-OXO-2H-PYRAN-2-YL]ETHYL]-1-NAPHTHALENOL
DB08330 METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE
DB08453 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE
DB08689 UBIQUINONE-1
DB08690 UBIQUINONE-2
DB08837 Tetraethylammonium
DB08912 Dabrafenib
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