DT-Web

DB02196 - Uridine-Diphosphate-N-Acetylgalactosamine


Identification
Name Uridine-Diphosphate-N-Acetylgalactosamine
Accession Number DB02196 (EXPT03169)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 607.3537
Groups experimental
Monoisotopic Weight 607.081569477
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Exostosin-like 2
Name Exostosin-like 2
Gene Name EXTL2
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
UDP-N-acetylhexosamine pyrophosphorylase
Name UDP-N-acetylhexosamine pyrophosphorylase
Gene Name UAP1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.9608
UDP-glucose 4-epimerase
Name UDP-glucose 4-epimerase
Gene Name GALE
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.4299
UDP-N-acetylglucosamine 2-epimerase
Name UDP-N-acetylglucosamine 2-epimerase
Gene Name wecB
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.8416
Histo-blood group ABO system transferase
Name Histo-blood group ABO system transferase
Gene Name ABO
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 2.0767
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
Name UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
Gene Name murG
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.8738
WbpP
Name WbpP
Gene Name Not Available
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.8441

Predictions


Id Partner name Gene Name Score
3461 UDP-glucose 4-epimerase galE 1.4299
3524 DNA beta-glucosyltransferase bgt 0.2416
2590 Galactose-1-phosphate uridylyltransferase galT 0.2242
520 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA 0.2228
2306 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA 0.2228
2367 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA 0.2228
5252 Bifunctional protein glmU glmU 0.2228
6789 Bifunctional protein glmU glmU 0.2228
2439 Alpha,alpha-trehalose-phosphate synthase [UDP-forming] otsA 0.2103
3697 Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase glmU 0.1789
3478 Glucose-1-phosphate thymidylyltransferase rmlA 0.1547
4277 Glucose-1-phosphate thymidylyltransferase rmlA 0.1547
287 Beta-1,4-galactosyltransferase 1 B4GALT1 0.1277
3523 Spore coat polysaccharide biosynthesis protein spsA spsA 0.0998
4482 UDP-galactose 4-epimerase galE 0.0934
2291 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 B3GAT1 0.0869
3408 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 B3GAT3 0.0868
2555 Pol polyprotein pol 0.0697
3242 Pol polyprotein gag-pol 0.0697
3471 Pol polyprotein gag-pro-pol 0.0697
5256 Pol polyprotein pol 0.0697
6469 Pol polyprotein gag-pol 0.0697
6565 Pol polyprotein Not Available 0.0697
702 UMP-CMP kinase CMPK1 0.0626
6389 Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial ETFDH 0.0146
4006 Succinate dehydrogenase cytochrome b560 subunit, mitochondrial SDHC 0.0102
4001 Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial SDHB 0.0102
197 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial SDHA 0.0097
6359 Cytochrome b-c1 complex subunit 8 UQCRQ 0.0096
6358 Cytochrome b-c1 complex subunit 6, mitochondrial UQCRH 0.0096
6357 Cytochrome b-c1 complex subunit 2, mitochondrial UQCRC2 0.0096
6363 Cytochrome b-c1 complex subunit 9 UQCR10 0.0094
6362 Cytochrome b-c1 complex subunit 7 UQCRB 0.0094
6360 Cytochrome b-c1 complex subunit Rieske, mitochondrial UQCRFS1 0.0094
1495 Ubiquinol-cytochrome-c reductase complex core protein 1, mitochondrial UQCRC1 0.0094
6356 Cytochrome c1, heme protein, mitochondrial CYC1 0.0094
1227 Cytochrome b MT-CYB 0.0094
6386 Cytochrome b petB 0.0094
6937 Cytochrome b MT-CYB 0.0094
3999 Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial SDHD 0.0088
4435 L-aspartate dehydrogenase nadX 0.0075
4495 3-oxoacyl-(Acyl carrier protein) reductase TM_1169 0.0075
4505 Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase bphB 0.0075
4472 Glucose 1-dehydrogenase Not Available 0.0075
4423 Levodione reductase lvr 0.0075
4428 Redox-sensing transcriptional repressor rex rex 0.0075
4475 Hypothetical protein Rv0046c/MT0052 ino1 0.0075
4447 Hypothetical protein yhfP yhfP 0.0075
4443 Quinate/shikimate dehydrogenase ydiB 0.0075
3381 Alcohol dehydrogenase Not Available 0.0075
4508 Alcohol dehydrogenase adhA 0.0075
4449 ADP-ribosyltransferase Not Available 0.0075
4448 L-2-hydroxyisocaproate dehydrogenase Not Available 0.0075
4336 Glyceraldehyde 3-phosphate dehydrogenase Not Available 0.0075
4436 Glyceraldehyde 3-phosphate dehydrogenase tthHB8IM 0.0075
4497 Benzyl alcohol dehydrogenase xylB 0.0075
4414 Dehydrogenase TT_P0035 0.0075
2350 3-isopropylmalate dehydrogenase leuB 0.0075
3092 3-isopropylmalate dehydrogenase leuB 0.0075
4471 CDP-D-glucose-4,6-dehydratase ascB 0.0075
4418 AGR_L_3209p AGR_L_3209 0.0075
4507 Alanine dehydrogenase ald 0.0075
4446 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase Not Available 0.0075
4455 Glycerol dehydrogenase gldA 0.0075
4506 Myo-inositol-1-phosphate synthase-related protein TM_1419 0.0075
3735 NAD(P) transhydrogenase subunit alpha part 1 pntAA 0.0075
4466 Glutathione-independent formaldehyde dehydrogenase fdhA 0.0075
4502 Formate dehydrogenase Not Available 0.0075
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.0075
3726 D-3-phosphoglycerate dehydrogenase serA 0.0075
4291 D-3-phosphoglycerate dehydrogenase serA 0.0075
4487 Transcriptional regulator nadR nadR 0.0075
4456 Inorganic polyphosphate/ATP-NAD kinase ppnK 0.0075
4451 Vip2Ac vip2Ac 0.0075
4467 Alpha-glucosidase, putative TM_0752 0.0075
3729 Citrate synthase gltA 0.0075
4575 Citrate synthase cit 0.0075
4580 Citrate synthase gltA 0.0075
4500 L-lactate dehydrogenase 2 ldh2 0.0075
3177 dTDP-glucose 4,6-dehydratase rfbB 0.0066
4499 dTDP-glucose 4,6-dehydratase rmlB 0.0066
4427 TDP-glucose-4,6-dehydratase desIV 0.0066
4486 Phenol 2-hydroxylase component B pheA2 0.0065
4503 NADPH-flavin oxidoreductase frp 0.0065
2967 CDP-paratose 2-epimerase rfbE 0.0065
4509 Acetoin(diacetyl) reductase budC 0.0065
2831 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase Not Available 0.0065
3059 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase fabG3 0.0065
3671 7-alpha-hydroxysteroid dehydrogenase hdhA 0.0065
4439 Ferredoxin reductase bphA4 0.0065
6698 Dehydrogenase/reductase SDR family member 4-like 2 DHRS4L2 0.0065
3615 Dihydrodipicolinate reductase dapB 0.0065
3618 Dihydrodipicolinate reductase dapB 0.0065
4462 Dihydrodipicolinate reductase dapB 0.0065
4498 Ornithine cyclodeaminase PP3533 0.0065
3081 3-dehydroquinate synthase aroB 0.0065
2538 6-phospho-beta-glucosidase bglT bglT 0.0065
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0065
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0065
1199 GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 ART1 0.0065
2336 2,3-diketo-L-gulonate reductase dlgD 0.0065
3401 D-2-hydroxyisocaproate dehydrogenase Not Available 0.0065
2018 Deoxyhypusine synthase DHPS 0.0065
4477 Dihydrolipoyl dehydrogenase lpdV 0.0065
5077 Dihydrolipoyl dehydrogenase Not Available 0.0065
5117 Dihydrolipoyl dehydrogenase lpd 0.0065
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0065
3598 dTDP-4-dehydrorhamnose reductase rfbD 0.0065
4496 C-terminal-binding protein 1 CTBP1 0.0065
2881 Gamma-aminobutyraldehyde dehydrogenase prr 0.0065
126 D-lactate dehydrogenase dld 0.0065
3545 D-lactate dehydrogenase Not Available 0.0065
4510 D-lactate dehydrogenase ldhA 0.0065
2424 L-lactate dehydrogenase ldh 0.0065
2641 L-lactate dehydrogenase Not Available 0.0065
4437 L-lactate dehydrogenase ldh 0.0065
4442 L-lactate dehydrogenase ldh 0.0065
2591 Urocanate hydratase hutU 0.0065
2507 Diphtheria toxin Not Available 0.0065
2393 Maltose-6'-phosphate glucosidase glvA 0.0065
4450 Iota toxin component Ia Not Available 0.0065
2683 Mono-ADP-ribosyltransferase C3 C3 0.006
3296 Nicotinamide mononucleotide adenylyltransferase 1 NMNAT1 0.006
2799 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal Not Available 0.006
4318 Siroheme synthase cysG 0.006
711 UDP-glucose 6-dehydrogenase UGDH 0.006
3672 UDP-glucose 6-dehydrogenase hasB 0.006
3367 GDP-mannose 6-dehydrogenase algD 0.006
3736 Glyceraldehyde-3-phosphate dehydrogenase A gapA 0.006
4343 Alpha-glucosidase aglA 0.006
4440 NADH peroxidase npr 0.006
816 Biliverdin reductase A BLVRA 0.006
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.006
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.006
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.006
4476 Mannitol dehydrogenase mtlD 0.0058
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0057
646 Malate dehydrogenase, cytoplasmic MDH1 0.0057
597 Dihydropteridine reductase QDPR 0.0057
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.0057
363 NADP-dependent malic enzyme, mitochondrial ME3 0.0057
396 Alcohol dehydrogenase 4 ADH4 0.0057
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.0057
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0057
328 Sorbitol dehydrogenase SORD 0.0057
2434 NH(3)-dependent NAD(+) synthetase nadE 0.0057
2910 NH(3)-dependent NAD(+) synthetase nadE 0.0057
3217 NH(3)-dependent NAD(+) synthetase nadE 0.0057
2617 Nitric oxide synthase oxygenase nos 0.0057
2701 Nitric oxide synthase oxygenase nos 0.0057
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.0057
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.0057
3333 Nicotinamide mononucleotide adenylyltransferase 3 NMNAT3 0.0057
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.0057
3070 Adenosylhomocysteinase AHCY 0.0057
4424 Adenosylhomocysteinase PFE1050w 0.0057
6278 Adenosylhomocysteinase ahcY 0.0057
2826 Glucose--fructose oxidoreductase gfo 0.0057
3191 Histidinol dehydrogenase hisD 0.0057
63 Malate dehydrogenase mdh 0.0056
2329 Malate dehydrogenase mdh 0.0056
3445 Malate dehydrogenase mdh 0.0056
4420 Malate dehydrogenase mdh 0.0056
4438 Malate dehydrogenase mdh 0.0056
12 Alcohol dehydrogenase class 3 ADH5 0.0055
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.0055
77 L-lactate dehydrogenase B chain LDHB 0.0055
327 Glutathione reductase gor 0.0054
5110 Glutathione reductase GR2 0.0054
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0054
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0054
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0054
473 L-lactate dehydrogenase A chain LDHA 0.0053
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0053
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0053
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0053
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0053
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0053
2286 Isocitrate dehydrogenase [NADP] icd 0.0052
2302 Isocitrate dehydrogenase [NADP] icd 0.0052
2771 Isocitrate dehydrogenase [NADP] icd 0.0052
4491 DNA ligase, NAD-dependent ligA 0.0052
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0051
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0051
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.005
611 Retinal dehydrogenase 1 ALDH1A1 0.0046
251 Alcohol dehydrogenase 1A ADH1A 0.0046
569 Retinal dehydrogenase 2 ALDH1A2 0.0046
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0046
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0045
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0045
444 Alcohol dehydrogenase 1B ADH1B 0.0044
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0043
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0043
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0043
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0043
714 Glutathione reductase, mitochondrial GSR 0.0041
517 Alcohol dehydrogenase 1C ADH1C 0.004
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.004
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