DT-Web

Histo-blood group ABO system transferase


Partner ID 237
Name Histo-blood group ABO system transferase
Synonyms 708
Gene name ABO
General function Involved in transferase activity, transferring hexosyl groups
Specific function This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens:A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity
Gene sequence + ...

ATGGCCGAGGTGTTGCGGACGCTGGCCGGAAAACCAAAATGCCACGCACTTCGACCTATGATCCTTTTCCTAATAATGCTTGTCTTGGTCTTGTTTGGTTACGGGGTCCTAAGCCCCAGAAGTCTAATGCCAGGAAGCCTGGAACGGGGGTTCTGCATGGCTGTTAGGGAACCTGACCATCTGCAGCGCGTCTCGTTGCCAAGGATGGTCTACCCCCAGCCAAAGGTGCTGACACCGTGGAAGGATGTCCTCGTGGTGACCCCTTGGCTGGCTCCCATTGTCTGGGAGGGCACATTCAACATCGACATCCTCAACGAGCAGTTCAGGCTCCAGAACACCACCATTGGGTTAACTGTGTTTGCCATCAAGAAATACGTGGCTTTCCTGAAGCTGTTCCTGGAGACGGCGGAGAAGCACTTCATGGTGGGCCACCGTGTCCACTACTATGTCTTCACCGACCAGCTGGCCGCGGTGCCCCGCGTGACGCTGGGGACCGGTCGGCAGCTGTCAGTGCTGGAGGTGCGCGCCTACAAGCGCTGGCAGGACGTGTCCATGCGCCGCATGGAGATGATCAGTGACTTCTGCGAGCGGCGCTTCCTCAGCGAGGTGGATTACCTGGTGTGCGTGGACGTGGACATGGAGTTCCGCGACCACGTGGGCGTGGAGATCCTGACTCCGCTGTTCGGCACCCTGCACCCCGGCTTCTACGGAAGCAGCCGGGAGGCCTTCACCTACGAGCGCCGGCCCCAGTCCCAGGCCTACATCCCCAAGGACGAGGGCGATTTCTACTACCTGGGGGGGTTCTTCGGGGGGTCGGTGCAAGAGGTGCAGCGGCTCACCAGGGCCTGCCACCAGGCCATGATGGTCGACCAGGCCAACGGCATCGAGGCCGTGTGGCACGACGAGAGCCACCTGAACAAGTACCTGCTGCGCCACAAACCCACCAAGGTGCTCTCCCCCGAGTACTTGTGGGACCAGCAGCTGCTGGGCTGGCCCGCCGTCCTGAGGAAGCTGAGGTTCACTGCGGTGCCCAAGAACCACCAGGCGGTCCGGAACCCGTGA
Protein sequence + ...

MAEVLRTLAGKPKCHALRPMILFLIMLVLVLFGYGVLSPRSLMPGSLERGFCMAVREPDHLQRVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKDEGDFYYLGGFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPKNHQAVRNP
GO Classification
component
cell
membrane
function
catalytic activity
transferase activity
transferase activity, transferring glycosyl groups
transferase activity, transferring hexosyl groups
process
physiological process
metabolism
macromolecule metabolism
carbohydrate metabolism
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB02196 Uridine-Diphosphate-N-Acetylgalactosamine
DB03435 Uridine-5'-Diphosphate
DB03501 Uridine Diphosphate Galactose
DB03772 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,5-Diol
DB04141 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
DB04678 H TYPE II TRISACCHARIDE
DB04679 H TYPE I TRISACCHARIDE
DB04680 GALACTOSE GREASE
DB04681 BETA-METHYLLACTOSIDE
DB07341 octyl 3-amino-3-deoxy-2-O-(2,6-dideoxy-alpha-L-lyxo-hexopyranosyl)-beta-D-galactopyranoside
DB07357 4-AMINO-2-HEXYLOXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,5-DIOL
DB07378 4-AMINO-2-OCTYLOXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,5-DIOL
DB07633 octyl 3-deoxy-2-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-xylo-hexopyranoside

Associated as Prediction

Id Name
DB00139 Succinic acid
DB00141 N-Acetyl-D-glucosamine
DB00441 Gemcitabine
DB00709 Lamivudine
DB00756 Hexachlorophene
DB01694 D-tartaric acid
DB01861 Glucose-Uridine-C1,5'-Diphosphate
DB01891 Tl-3-093
DB01907 Nicotinamide-Adenine-Dinucleotide
DB02007 Alpha-D-Glucose-6-Phosphate
DB02196 Uridine-Diphosphate-N-Acetylgalactosamine
DB02333 Deoxyuridine-5'-Triphosphate
DB02421 Uridine-5'-Diphosphate-Mannose
DB02696 6-Aminohexyl-Uridine-C1,5'-Diphosphate
DB02790 Phenyl-Uridine-5'-Diphosphate
DB03013 Di(N-Acetyl-D-Glucosamine)
DB03041 Udp-Glucuronic Acid
DB03095 Tetramethylammonium Ion
DB03397 Uridine-Diphosphate-N-Acetylglucosamine
DB03403 Cytidine-5'-Monophosphate
DB03431 Adenosine-5'-Diphosphate
DB03435 Uridine-5'-Diphosphate
DB03488 Uridine-5'-Diphosphate-2-Deoxy-2-Fluoro-Alpha-D-Galactose
DB03501 Uridine Diphosphate Galactose
DB03664 P1-(Adenosine-5'-P5-(Uridine-5')Pentaphosphate
DB03685 Uridine-5'-Monophosphate
DB03772 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,5-Diol
DB03800 2'-deoxyuridylic acid
DB03814 2-(N-Morpholino)-Ethanesulfonic Acid
DB04097 Uridine-5'-Diphosphate-4-Deoxy-4-Fluoro-Alpha-D-Galactose
DB04141 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
DB04355 Uridine-5'-Monophosphate Glucopyranosyl-Monophosphateester
DB04444 Tetrafluoroaluminate Ion
DB04657 Carboxin
DB04678 H TYPE II TRISACCHARIDE
DB04679 H TYPE I TRISACCHARIDE
DB04680 GALACTOSE GREASE
DB04681 BETA-METHYLLACTOSIDE
DB04741 Myxothiazol
DB04795 Thenoyltrifluoroacetone
DB04799 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole
DB07341 octyl 3-amino-3-deoxy-2-O-(2,6-dideoxy-alpha-L-lyxo-hexopyranosyl)-beta-D-galactopyranoside
DB07357 4-AMINO-2-HEXYLOXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,5-DIOL
DB07365 NAPHTHALEN-2-YL-3-ALANINE
DB07378 4-AMINO-2-OCTYLOXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,5-DIOL
DB07401 METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE
DB07633 octyl 3-deoxy-2-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-xylo-hexopyranoside
DB07636 5-HEPTYL-6-HYDROXY-1,3-BENZOTHIAZOLE-4,7-DIONE
DB07763 (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE
DB07778 FAMOXADONE
DB08253 NAM NAPTHYLAMINOALANINE
DB08330 METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE
DB08453 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE
DB08689 UBIQUINONE-1
DB08690 UBIQUINONE-2
↑