DT-Web

NADPH-flavin oxidoreductase


Partner ID 4503
Name NADPH-flavin oxidoreductase
Synonyms 6896
Gene name frp
General function Involved in oxidoreductase activity
Specific function Involved in bioluminescence. It is a good supplier of reduced flavin mononucleotide (FMNH2) to the bioluminescence reaction
Gene sequence + ...

ATGAACAATACGATTGAAACCATTCTTGCTCATCGCTCTATCCGAAAATTCACCGCAGTTCCTATTACTGATGAACAAAGACAAACCATCATTCAAGCAGGTTTAGCTGCGTCTTCTTCTAGTATGCTTCAAGTCGTCTCAATCGTTCGAGTGACTGACTCTGAAAAGCGTAACGAATTGGCTCAATTTGCTGGTAACCAAGCTTATGTTGAAAGTGCGGCTGAGTTCTTAGTGTTTTGTATTGATTATCAGCGCCATGCAACCATCAATCCTGATGTACAGGCAGACTTTACAGAACTAACTCTGATTGGAGCAGTAGATTCTGGAATCATGGCACAAAACTGCTTGCTTGCAGCCGAGTCTATGGGATTAGGTGGCGTATATATTGGAGGACTAAGGAATAGCGCAGCTCAAGTTGATGAGCTATTGGGCTTACCGGAAAATAGCGCGGTGTTGTTTGGTATGTGCTTAGGGCATCCCGATCAAAATCCCGAAGTAAAGCCACGCCTACCTGCACATGTGGTTGTTCATGAAAATCAATACCAAGAGCTAAATTTAGATGATATTCAGAGCTACGATCAAACTATGCAAGCGTATTATGCGAGCCGTACAAGCAATCAAAAACTGAGTACATGGTCGCAAGAAGTCACTGGGAAGCTTGCTGGTGAGTCGCGACCTCATATTCTGCCGTACTTGAACAGTAAGGGGCTAGCAAAACGCTAA
Protein sequence + ...

MNNTIETILAHRSIRKFTAVPITDEQRQTIIQAGLAASSSSMLQVVSIVRVTDSEKRNELAQFAGNQAYVESAAEFLVFCIDYQRHATINPDVQADFTELTLIGAVDSGIMAQNCLLAAESMGLGGVYIGGLRNSAAQVDELLGLPENSAVLFGMCLGHPDQNPEVKPRLPAHVVVHENQYQELNLDDIQSYDQTMQAYYASRTSNQKLSTWSQEVTGKLAGESRPHILPYLNSKGLAKR
GO Classification
function
catalytic activity
oxidoreductase activity
process
physiological process
metabolism
cellular metabolism
generation of precursor metabolites and energy
electron transport
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB01907 Nicotinamide-Adenine-Dinucleotide
DB03247 Riboflavin Monophosphate

Associated as Prediction

Id Name
DB00114 Pyridoxal Phosphate
DB00140 Riboflavin
DB00142 L-Glutamic Acid
DB00143 Glutathione
DB00155 L-Citrulline
DB00157 NADH
DB00162 Vitamin A
DB00166 Lipoic Acid
DB00262 Carmustine
DB00305 Mitomycin
DB00336 Nitrofurazone
DB00435 Nitric Oxide
DB00536 Guanidine
DB00544 Fluorouracil
DB00609 Ethionamide
DB00665 Nilutamide
DB00688 Mycophenolate mofetil
DB00694 Daunorubicin
DB00698 Nitrofurantoin
DB00727 Nitroglycerin
DB00742 Mannitol
DB00755 Tretinoin
DB00756 Hexachlorophene
DB00822 Disulfiram
DB00865 Benzphetamine
DB00898 Ethanol
DB00951 Isoniazid
DB00997 Doxorubicin
DB01024 Mycophenolic acid
DB01097 Leflunomide
DB01101 Capecitabine
DB01117 Atovaquone
DB01213 Fomepizole
DB01466 Ethylmorphine
DB01536 4-Androstenedione
DB01561 Androstanedione
DB01612 Amyl Nitrite
DB01644 3,6-Dihydroxy-Xanthene-9-Propionic Acid
DB01650 trans-2-hydroxycinnamic acid
DB01676 Trinitrotoluene
DB01677 Fumarate
DB01691 Indole Naphthyridinone
DB01693 Ribavirin Monophosphate
DB01694 D-tartaric acid
DB01708 Dehydroepiandrosterone
DB01711 2,3,4,5,6-Pentafluorobenzyl Alcohol
DB01713 Udp-Alpha-D-Xylopyranose
DB01727 Isocitric Acid
DB01752 S-Adenosyl-L-Homocysteine
DB01769 Double Oxidized Cysteine
DB01792 Adenylyl-3'-5'-Phospho-Uridine-3'-Monophosphate
DB01821 L-N(Omega)-Nitroarginine-2,4-L-Diaminobutyric Amide
DB01848 Isocitrate Calcium Complex
DB01854 5-Bromonicotinamide
DB01861 Glucose-Uridine-C1,5'-Diphosphate
DB01865 3-(6-Aminopyridin-3-Yl)-N-Methyl-N-[(1-Methyl-1h-Indol-2-Yl)Methyl]Acrylamide
DB01907 Nicotinamide-Adenine-Dinucleotide
DB01942 Formic Acid
DB01971 trans-urocanic acid
DB01992 Coenzyme A
DB01997 3-Bromo-7-Nitroindazole
DB02007 Alpha-D-Glucose-6-Phosphate
DB02027 N-{(4s)-4-Amino-5-[(2-Aminoethyl)Amino]Pentyl}-N'-Nitroguanidine
DB02044 N-(3-(Aminomethyl)Benzyl)Acetamidine
DB02059 Adenosine-5-Diphosphoribose
DB02060 Cyclohexanone
DB02073 Biliverdine Ix Alpha
DB02077 L-N(Omega)-Nitroarginine-(4r)-Amino-L-Proline Amide
DB02111 3-Hydroxyisoxazole-4-Carboxylic Acid
DB02115 Daidzin
DB02123 Glycochenodeoxycholic Acid
DB02131 N-1-Methylheptylformamide
DB02143 N-Isopropyl-N'-Hydroxyguanidine
DB02147 Cyclo-Tetrametavanadate
DB02153 3-Sulfinoalanine
DB02164 N-Sulfo-Flavin Mononucleotide
DB02187 Equilin
DB02190 2-Oxalosuccinic Acid
DB02196 Uridine-Diphosphate-N-Acetylgalactosamine
DB02205 6-(1,1-Dimethylallyl)-2-(1-Hydroxy-1-Methylethyl)-2,3-Dihydro-7h-Furo[3,2-G]Chromen-7-One
DB02209 Pyridoxine-5'-Phosphate
DB02212 Pyrophosphate 2-
DB02234 Ethylisothiourea
DB02249 2-Ethoxyethanol
DB02262 Orotic Acid
DB02263 Glyceraldehyde-3-Phosphate
DB02279 Benzoylformic Acid
DB02303 (5s)-5-Iododihydro-2,4(1h,3h)-Pyrimidinedione
DB02323 EM-1745
DB02329 Carbenoxolone
DB02338 Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate
DB02379 Beta-D-Glucose
DB02383 Tolrestat
DB02401 4-Hydroxy-1,2,5-Oxadiazole-3-Carboxylic Acid
DB02421 Uridine-5'-Diphosphate-Mannose
DB02481 N-Benzylformamide
DB02483 Etheno-Nad
DB02508 Isopentyl Pyrophosphate
DB02553 Glutathionylspermidine Disulfide
DB02592 Carbaphosphonate
DB02596 Alpha,Beta-Methyleneadenosine-5'-Triphosphate
DB02613 Decylamine-N,N-Dimethyl-N-Oxide
DB02621 Latrunculin A
DB02637 Oxaloacetate Ion
DB02644 N-Omega-Propyl-L-Arginine
DB02659 Cholic Acid
DB02692 (6r,1'r,2's)-5,6,7,8 Tetrahydrobiopterin
DB02701 Nicotinamide
DB02721 4-Iodopyrazole
DB02727 N-Butyl-N'-Hydroxyguanidine
DB02757 Pyrazole
DB02772 Sucrose
DB02790 Phenyl-Uridine-5'-Diphosphate
DB02820 1-Azepan-1-Yl-2-Phenyl-2-(4-Thioxo-1,4-Dihydro-Pyrazolo[3,4-D]Pyrimidin-5-Yl)Ethanone Adduct
DB02822 Para-Bromobenzyl Alcohol
DB02854 Aetiocholanolone
DB02871 3-Butylthiolane 1-Oxide
DB02895 3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol
DB02901 Dihydrotestosterone
DB02926 2-Oxo-Glutaric Acid
DB02937 Gamma-Arsono-Beta, Gamma-Methyleneadenosine-5'-Diphosphate
DB02944 Alpha-D-Mannose
DB02990 C16-Fatty-Acyl-Substrate-Mimic
DB02991 S-Ethyl-N-[4-(Trifluoromethyl)Phenyl]Isothiourea
DB03014 Heme
DB03020 5-Beta-D-Ribofuranosylnicotinamide Adenine Dinucleotide
DB03030 4-(2-Thienyl)-1-(4-Methylbenzyl)-1h-Imidazole
DB03041 Udp-Glucuronic Acid
DB03048 6-Carboxymethyluracil
DB03059 Acetoacetyl-Coenzyme A
DB03061 (R)-N-(1-Methyl-Hexyl)-Formamide
DB03064 3-Decyl-2,5-Dioxo-4-Hydroxy-3-Pyrroline
DB03070 Selenazole-4-Carboxyamide-Adenine Dinucleotide
DB03095 Tetramethylammonium Ion
DB03144 N-Omega-Hydroxy-L-Arginine
DB03147 Flavin-Adenine Dinucleotide
DB03161 Thymidine-5'-Diphospho-Beta-D-Xylose
DB03162 4-Hydroxy-1,2,5-Thiadiazole-3-Carboxylic Acid
DB03169 (S)-Hmg-Coa
DB03192 3r-Hydroxydecanoyl-Coa
DB03211 (3-Formyl-but-3-Enyl)-Phosphonic Acid
DB03216 (1'r,2's)-9-(2-Hydroxy-3'-Keto-Cyclopenten-1-Yl)Adenine
DB03226 Trifluoroethanol
DB03227 Nicotinamide Mononucleotide
DB03228 5-[Bis-2(Chloro-Ethyl)-Amino]-2,4-Dintro-Benzamide
DB03229 2-Oxo-4-Methylpentanoic Acid
DB03247 Riboflavin Monophosphate
DB03273 3'-Oxo-Adenosine
DB03310 Oxidized Glutathione Disulfide
DB03323 Maltose
DB03331 N-Naphthalen-1-Ylmethyl-2'-[3,5-Dimethoxybenzamido]-2'-Deoxy-Adenosine
DB03345 Beta-Mercaptoethanol
DB03350 Cobalt Hexammine Ion
DB03382 S-Oxy Cysteine
DB03397 Uridine-Diphosphate-N-Acetylglucosamine
DB03410 4-hydroxycoumarin
DB03419 Uracil
DB03431 Adenosine-5'-Diphosphate
DB03435 Uridine-5'-Diphosphate
DB03449 N-(4-(2-((3-Chlorophenylmethyl)Amino)Ethyl)Phenyl)-2-Thiophecarboxamidine
DB03461 2'-Monophosphoadenosine 5'-Diphosphoribose
DB03478 2'-O-Acetyl Adenosine-5-Diphosphoribose
DB03480 Brequinar Analog
DB03499 Malate Ion
DB03501 Uridine Diphosphate Galactose
DB03518 (R)-Mevalonate
DB03523 6-Fluoro-2-(2'-Fluoro-1,1'-Biphenyl-4-Yl)-3-Methylquinoline-4-Carboxylic Acid
DB03534 3-[(Acetyl-Methyl-Amino)-Methyl]-4-Amino-N-Methyl-N-(1-Methyl-1h-Indol-2-Ylmethyl)-Benzamide
DB03554 5-Iodouracil
DB03559 Cyclohexylformamide
DB03589 Alpha-Ketomalonic Acid
DB03612 3-Hydroxybutyryl-Coenzyme A
DB03639 1-Guanidinium-7-Aminoheptane
DB03651 2,4,6-Trinitrophenol
DB03680 Tartronate
DB03698 5-Mercaptoethanol-2-Decenoyl-Coenzyme A
DB03703 Cyclohexanol
DB03704 12-Hydroxydodecanoic Acid
DB03707 S-Ethyl-N-Phenyl-Isothiourea
DB03710 N5-(1-Imino-3-Butenyl)-L-Ornithine
DB03723 2'-Deoxy-Thymidine-Beta-L-Rhamnose
DB03738 Pantothenoylaminoethenethiol
DB03751 2'deoxy-Thymidine-5'-Diphospho-Alpha-D-Glucose
DB03769 D-Eritadenine
DB03785 (3r,5r)-7-((1r,2r,6s,8r,8as)-2,6-Dimethyl-8-{[(2r)-2-Methylbutanoyl]Oxy}-1,2,6,7,8,8a-Hexahydronaphthalen-1-Yl)-3,5-Dihydroxyheptanoic Acid
DB03793 Benzoic Acid
DB03805 Antiproliferative Agent A771726
DB03811 Histidinol
DB03814 2-(N-Morpholino)-Ethanesulfonic Acid
DB03867 Meta-Nitro-Tyrosine
DB03884 3-Phenylpyruvic Acid
DB03892 5-N-Allyl-Arginine
DB03893 Thionicotinamide-Adenine-Dinucleotide
DB03940 Oxamic Acid
DB03948 6-Chloropurine Riboside, 5'-Monophosphate
DB03969 3-Acetyl Pyridine Adenine Dinucleotide
DB04023 Guanosine 5'-(Trihydrogen Diphosphate), P'-D-Mannopyranosyl Ester
DB04030 1,3,4,9-Tetrahydro-2-(Hydroxybenzoyl)-9-[(4-Hydroxyphenyl)Methyl]-6-Methoxy-2h-Pyrido[3,4-B]Indole
DB04065 N-Cyclopentyl-N-Cyclobutylformamide
DB04071 Cpad
DB04077 Glycerol
DB04097 Uridine-5'-Diphosphate-4-Deoxy-4-Fluoro-Alpha-D-Galactose
DB04099 Deamido-Nad+
DB04105 N-Heptylformamide
DB04113 N-Formylpiperidine
DB04122 Beta-D-Glucose-6-Phosphate
DB04137 Guanosine-5'-Triphosphate
DB04138 2,4-Dinitro,5-[Bis(2-Bromoethyl)Amino]-N-(2',3'-Dioxopropyl)Benzamide
DB04147 Lauryl Dimethylamine-N-Oxide
DB04153 S-Hydroxymethyl Glutathione
DB04160 Diphosphate
DB04200 Matairesinol
DB04223 Nitroarginine
DB04253 CB1954
DB04267 Dipicolinic Acid
DB04272 Citric Acid
DB04279 3-Isopropylmalic Acid
DB04281 2-[4-(4-Chlorophenyl)Cyclohexylidene]-3,4-Dihydroxy-1(2h)-Naphthalenone
DB04289 Genz-10850
DB04312 2,3-Difluorobenzyl Alcohol
DB04345 7,8-dimethylalloxazine
DB04355 Uridine-5'-Monophosphate Glucopyranosyl-Monophosphateester
DB04363 Mesobiliverdin Iv Alpha
DB04374 4-Carboxy-5-(1-Pentyl)Hexylsulfanyl-1,2,3-Triazole
DB04381 Crotonaldehyde
DB04392 Bishydroxy[2h-1-Benzopyran-2-One,1,2-Benzopyrone]
DB04393 Diclosan
DB04401 [Formylmethyl]Trimethyl-Ammonium, N,N,N-Trimethylammonium Acetaldehyde
DB04447 1,4-Dithiothreitol
DB04448 2,4-Difluorobenzyl Alcohol 2,4-Difluoro-1-(Hydroxymethyl)Benzene
DB04477 N-1,2,3,4-Tetrahydronaphth-1-Yl-2'-[3,5-Dimethoxybenzamido]-2'-Deoxy-Adenosine
DB04478 Cp-166572, 2-Hydroxymethyl-4-(4-N,N-Dimethylaminosulfonyl-1-Piperazino)-Pyrimidine
DB04522 Phosphonoserine
DB04528 2,4-Dinitrophenol
DB04555 Cytidine-5'-Diphosphate
DB04566 Inosinic Acid
DB04583 5-(AMINOCARBONYL)-1,1':4',1''-TERPHENYL-3-CARBOXYLICACID
DB04640 Naphthalene-2,6-disulfonic acid
DB04641 3,7-DIHYDROXYNAPHTHALENE-2-CARBOXYLIC ACID
DB04786 Suramin
DB06770 Benzyl alcohol
DB06979 5-(dodecylthio)-1H-1,2,3-triazole-4-carboxylic acid
DB07040 2-amino-7-fluoro-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxamide
DB07041 N-[2-(2,4-diaminopyrido[2,3-d]pyrimidin-7-yl)-2-methylpropyl]-4-phenoxybenzamide
DB07042 7-amino-2-tert-butyl-4-{[2-(1H-imidazol-4-yl)ethyl]amino}pyrido[2,3-d]pyrimidine-6-carboxamide
DB07043 7-amino-2-tert-butyl-4-(4-pyrimidin-2-ylpiperazin-1-yl)pyrido[2,3-d]pyrimidine-6-carboxamide
DB07060 3-(INDOL-3-YL) LACTATE
DB07090 (3S)-N-(3-CHLORO-2-METHYLPHENYL)-1-CYCLOHEXYL-5-OXOPYRROLIDINE-3-CARBOXAMIDE
DB07123 N-(4-METHYLBENZOYL)-4-BENZYLPIPERIDINE
DB07155 (3S)-1-CYCLOHEXYL-5-OXO-N-PHENYLPYRROLIDINE-3-CARBOXAMIDE
DB07178 5-PENTYL-2-PHENOXYPHENOL
DB07188 (3S)-1-CYCLOHEXYL-N-(3,5-DICHLOROPHENYL)-5-OXOPYRROLIDINE-3-CARBOXAMIDE
DB07192 (3S)-N-(3-BROMOPHENYL)-1-CYCLOHEXYL-5-OXOPYRROLIDINE-3-CARBOXAMIDE
DB07222 (3S)-N-(5-CHLORO-2-METHYLPHENYL)-1-CYCLOHEXYL-5-OXOPYRROLIDINE-3-CARBOXAMIDE
DB07287 2-(2,4-DICHLOROPHENOXY)-5-(PYRIDIN-2-YLMETHYL)PHENOL
DB07347 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE
DB07373 ANDROSTA-1,4-DIENE-3,17-DIONE
DB07393 2-(2-PHENYL-3-PYRIDIN-2-YL-4,5,6,7-TETRAHYDRO-2H-ISOPHOSPHINDOL-1-YL)PYRIDINE
DB07443 (2Z)-N-biphenyl-4-yl-2-cyano-3-hydroxybut-2-enamide
DB07559 (2Z)-2-cyano-N-(2,2'-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide
DB07561 (2Z)-2-cyano-N-(3'-ethoxybiphenyl-4-yl)-3-hydroxybut-2-enamide
DB07646 UNDECYLAMINE-N,N-DIMETHYL-N-OXIDE
DB07714 6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)HEXANOIC ACID
DB07837 [4-(5-naphthalen-2-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]acetic acid
DB07907 (2S)-2-HYDROXYOCTANOIC ACID
DB07975 2-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID
DB07976 3-{[(3-FLUORO-3'-METHOXYBIPHENYL-4-YL)AMINO]CARBONYL}THIOPHENE-2-CARBOXYLIC ACID
DB07977 3-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)THIOPHENE-2-CARBOXYLIC ACID
DB07978 2-({[2,3,5,6-TETRAFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENTA-1,3-DIENE-1-CARBOXYLIC ACID
DB08006 N-anthracen-2-yl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
DB08008 5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine
DB08018 N-{(3S,4S)-4-[(6-AMINO-4-METHYLPYRIDIN-2-YL)METHYL]PYRROLIDIN-3-YL}-N'-(4-CHLOROBENZYL)ETHANE-1,2-DIAMINE
DB08019 N-{(3R,4S)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-(3-chlorobenzyl)ethane-1,2-diamine
DB08169 (2Z)-N-biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide
DB08172 (2Z)-N-(3-chloro-2'-methoxybiphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide
DB08191 4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid
DB08249 3,6,9,12,15-PENTAOXATRICOSAN-1-OL
DB08265 2-(TOLUENE-4-SULFONYL)-2H-BENZO[D][1,2,3]DIAZABORININ-1-OL
DB08604 TRICLOSAN
DB08605 6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL
DB08880 Teriflunomide
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