DT-Web

DB03410 - 4-hydroxycoumarin


Identification
Name 4-hydroxycoumarin
Accession Number DB03410 (EXPT00215)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 162.1421
Groups experimental
Monoisotopic Weight 162.031694058
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Major NAD(P)H-flavin oxidoreductase
Name Major NAD(P)H-flavin oxidoreductase
Gene Name Not Available
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.8916

Predictions


Id Partner name Gene Name Score
6142 Solute carrier family 22 member 8 SLC22A8 0.1014
5179 Probable aromatic acid decarboxylase pad1 0.0118
5175 Hypothetical protein SMU.260 SMU_260 0.0118
5200 NADH dehydrogenase nox 0.0118
5201 FMN-binding protein DvMF_2023 0.0118
5181 Hypothetical protein yhdA azr 0.0118
5178 Protein nrdI nrdI 0.0118
3293 Flavodoxin Not Available 0.0118
4614 Flavodoxin DVU_2680 0.0118
5172 Flavodoxin isiB 0.0118
5173 Flavodoxin isiB 0.0118
5182 Flavodoxin fldA 0.0118
5198 Flavodoxin-1 fldA 0.0118
5170 Epidermin decarboxylase epiD 0.0118
2586 Isopentenyl-diphosphate Delta-isomerase idi 0.0118
5187 Isopentenyl-diphosphate delta-isomerase fni 0.0118
5199 Isopentenyl-diphosphate delta-isomerase fni 0.0118
5202 Nitroreductase family protein BC_1844 0.0118
5197 Trp repressor binding protein WrbA, putative DR_A0214 0.0118
5131 PhzG phzG 0.0118
5193 Phenazine biosynthesis protein phzG phzG 0.0118
5190 Rubredoxin-oxygen oxidoreductase roo 0.0118
4037 Hypothetical protein GPX1 0.0118
4297 Hypothetical protein SP_1951 0.0118
4521 Hypothetical protein BC_2969 0.0118
4540 Hypothetical protein TM_1070 0.0118
4555 Hypothetical protein MT1739 0.0118
4569 Hypothetical protein mshD 0.0118
4578 Hypothetical protein PA3270 0.0118
4747 Hypothetical protein PA3967 0.0118
5177 Hypothetical protein TM_0096 0.0118
5194 Hypothetical protein PA1204 0.0118
5240 Hypothetical protein Rv2991 0.0118
5370 Hypothetical protein TM_1158 0.0118
5710 Hypothetical protein Tb927.5.1360 0.0118
5191 Morphinone reductase morB 0.0118
4405 Nitric oxide reductase fprA 0.0118
4503 NADPH-flavin oxidoreductase frp 0.0109
5189 Trimethylamine dehydrogenase tmd 0.0109
4836 Ferredoxin-dependent glutamate synthase 2 gltS 0.0109
4407 FMN-dependent NADH-azoreductase azoR 0.0103
5169 FMN-dependent NADH-azoreductase azoR 0.0103
3680 Dihydroorotate dehydrogenase A pyrDA 0.0102
5206 Phosphopantothenoylcysteine decarboxylase PPCDC 0.0102
3766 Pyridoxamine 5'-phosphate oxidase pdxH 0.0102
5176 YtnJ moxC 0.0101
3507 Chorismate synthase aroC 0.0101
5171 Chorismate synthase aroC 0.0101
6608 Serine/threonine-protein kinase Sgk1 SGK1 0.0095
2775 Dihydroorotate dehydrogenase pyrD 0.0094
408 Riboflavin kinase RFK 0.0094
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0092
5180 L(+)-mandelate dehydrogenase mdlB 0.0089
685 Oxygen-insensitive NADPH nitroreductase nfsA 0.0088
6945 Oxygen-insensitive NADPH nitroreductase rdxA 0.0088
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0088
203 Pyridoxine-5'-phosphate oxidase PNPO 0.0083
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0083
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0083
4284 Pentaerythritol tetranitrate reductase onr 0.008
6268 Hydroxyacid oxidase 1 HAO1 0.0076
654 Flavin reductase BLVRB 0.0075
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0071
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0061
76 Nitric-oxide synthase, brain NOS1 0.006
4120 NADPH--cytochrome P450 reductase POR 0.0058
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