DT-Web

DB04363 - Mesobiliverdin Iv Alpha


Identification
Name Mesobiliverdin Iv Alpha
Accession Number DB04363 (EXPT02129)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 585.6701
Groups experimental
Monoisotopic Weight 585.271309936
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Flavin reductase
Name Flavin reductase
Gene Name BLVRB
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.5615

Predictions


Id Partner name Gene Name Score
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.1329
810 Heme oxygenase 1 HMOX1 0.0989
3391 Heme oxygenase 1 pbsA1 0.0989
408 Riboflavin kinase RFK 0.0486
5698 Riboflavin synthase alpha chain ribE 0.0462
3917 Methylenetetrahydrofolate reductase MTHFR 0.0249
3941 Amine oxidase [flavin-containing] A MAOA 0.0203
1729 Solute carrier family 22 member 6 SLC22A6 0.0153
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0092
3293 Flavodoxin Not Available 0.0065
4614 Flavodoxin DVU_2680 0.0065
5172 Flavodoxin isiB 0.0065
5173 Flavodoxin isiB 0.0065
5182 Flavodoxin fldA 0.0065
5181 Hypothetical protein yhdA azr 0.0065
5179 Probable aromatic acid decarboxylase pad1 0.0065
5197 Trp repressor binding protein WrbA, putative DR_A0214 0.0065
5200 NADH dehydrogenase nox 0.0065
5201 FMN-binding protein DvMF_2023 0.0065
5178 Protein nrdI nrdI 0.0065
5198 Flavodoxin-1 fldA 0.0065
5170 Epidermin decarboxylase epiD 0.0065
5175 Hypothetical protein SMU.260 SMU_260 0.0065
5202 Nitroreductase family protein BC_1844 0.0065
5131 PhzG phzG 0.0065
5193 Phenazine biosynthesis protein phzG phzG 0.0065
5190 Rubredoxin-oxygen oxidoreductase roo 0.0065
5191 Morphinone reductase morB 0.0065
4037 Hypothetical protein GPX1 0.0065
4297 Hypothetical protein SP_1951 0.0065
4521 Hypothetical protein BC_2969 0.0065
4540 Hypothetical protein TM_1070 0.0065
4555 Hypothetical protein MT1739 0.0065
4569 Hypothetical protein mshD 0.0065
4578 Hypothetical protein PA3270 0.0065
4747 Hypothetical protein PA3967 0.0065
5177 Hypothetical protein TM_0096 0.0065
5194 Hypothetical protein PA1204 0.0065
5240 Hypothetical protein Rv2991 0.0065
5370 Hypothetical protein TM_1158 0.0065
5710 Hypothetical protein Tb927.5.1360 0.0065
2586 Isopentenyl-diphosphate Delta-isomerase idi 0.0065
5187 Isopentenyl-diphosphate delta-isomerase fni 0.0065
5199 Isopentenyl-diphosphate delta-isomerase fni 0.0065
4405 Nitric oxide reductase fprA 0.0065
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.0063
666 NADP-dependent malic enzyme ME1 0.0062
646 Malate dehydrogenase, cytoplasmic MDH1 0.0061
11 NAD(P) transhydrogenase, mitochondrial NNT 0.006
76 Nitric-oxide synthase, brain NOS1 0.006
5326 Oxidoreductase, short chain dehydrogenase/reductase family TM_0441 0.0058
5346 Oxidoreductase, aldo/keto reductase family TM_1009 0.0058
5332 MtdA bifunctional protein mtdA 0.0058
5322 Oxidoreductase ydhF ydhF 0.0058
4403 Protein iolS iolS 0.0058
5333 Alcohol dehydrogenase, iron-containing TM_0920 0.0058
3772 3-oxoacyl-[acyl-carrier-protein] reductase fabG 0.0058
5157 Dehydrogenase/reductase SDR family member 11 DHRS11 0.0058
3778 NAD(P) transhydrogenase subunit beta pntB 0.0058
4503 NADPH-flavin oxidoreductase frp 0.0058
5330 General stress protein 69 yhdN 0.0058
5342 NADH-dependent butanol dehydrogenase, putative TM_0820 0.0058
5343 NADP-dependent fatty aldehyde dehydrogenase aldH 0.0058
5189 Trimethylamine dehydrogenase tmd 0.0058
4836 Ferredoxin-dependent glutamate synthase 2 gltS 0.0058
4120 NADPH--cytochrome P450 reductase POR 0.0057
5176 YtnJ moxC 0.0055
3680 Dihydroorotate dehydrogenase A pyrDA 0.0055
4407 FMN-dependent NADH-azoreductase azoR 0.0054
5169 FMN-dependent NADH-azoreductase azoR 0.0054
5206 Phosphopantothenoylcysteine decarboxylase PPCDC 0.0054
3766 Pyridoxamine 5'-phosphate oxidase pdxH 0.0054
3507 Chorismate synthase aroC 0.0054
5171 Chorismate synthase aroC 0.0054
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0052
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0052
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0052
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0051
2375 ADP-L-glycero-D-manno-heptose-6-epimerase hldD 0.0051
5073 Ferredoxin--NADP reductase petH 0.0051
5076 Ferredoxin--NADP reductase fpr 0.0051
5119 Ferredoxin--NADP reductase petH 0.0051
5121 Ferredoxin--NADP reductase fpr 0.0051
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0051
2775 Dihydroorotate dehydrogenase pyrD 0.005
6608 Serine/threonine-protein kinase Sgk1 SGK1 0.005
4582 Putative pteridine reductase 2 ptr2 0.0049
2636 Shikimate dehydrogenase aroE 0.0049
3515 Shikimate dehydrogenase aroE 0.0049
4628 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase gapN 0.0049
3446 NADP-dependent alcohol dehydrogenase adh 0.0049
2305 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 0.0049
989 L-xylulose reductase DCXR 0.0049
2286 Isocitrate dehydrogenase [NADP] icd 0.0049
2302 Isocitrate dehydrogenase [NADP] icd 0.0049
2771 Isocitrate dehydrogenase [NADP] icd 0.0049
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.0049
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.0049
5328 Prostaglandin F synthase Tb11.02.2310 0.0049
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0047
5180 L(+)-mandelate dehydrogenase mdlB 0.0046
685 Oxygen-insensitive NADPH nitroreductase nfsA 0.0046
6945 Oxygen-insensitive NADPH nitroreductase rdxA 0.0046
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0046
444 Alcohol dehydrogenase 1B ADH1B 0.0045
6862 Aldo-keto reductase family 1 member B10 AKR1B10 0.0045
2261 Major NAD(P)H-flavin oxidoreductase Not Available 0.0045
6297 Prostaglandin reductase 1 PTGR1 0.0045
4531 Putative ketoacyl reductase actIII 0.0045
3062 Aspartate-semialdehyde dehydrogenase asd 0.0045
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0044
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.0044
2675 Pteridine reductase 1 PTR1 0.0043
203 Pyridoxine-5'-phosphate oxidase PNPO 0.0043
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0043
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0043
1124 Sepiapterin reductase SPR 0.0042
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0042
2159 Quinone oxidoreductase CRYZ 0.0042
4284 Pentaerythritol tetranitrate reductase onr 0.0041
6268 Hydroxyacid oxidase 1 HAO1 0.0039
822 Aldose reductase AKR1B1 0.0039
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0038
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0038
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0037
365 Dihydrofolate reductase DHFR 0.0037
2381 Dihydrofolate reductase DFR1 0.0037
2833 Dihydrofolate reductase Not Available 0.0037
2931 Dihydrofolate reductase folA 0.0037
3544 Dihydrofolate reductase folA 0.0037
3682 Dihydrofolate reductase folA 0.0037
6642 Dihydrofolate reductase folA 0.0037
6756 Dihydrofolate reductase dfrA 0.0037
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0031
816 Biliverdin reductase A BLVRA 0.0018
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0018
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0018
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0018
343 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NDUFC1 0.0018
190 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 NDUFA4 0.0018
374 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NDUFB1 0.0018
475 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NDUFB2 0.0018
247 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUFA1 0.0018
41 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NDUFS8 0.0018
598 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NDUFA11 0.0018
755 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NDUFA3 0.0018
353 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 NDUFA4L2 0.0018
602 Acyl carrier protein, mitochondrial NDUFAB1 0.0018
313 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NDUFB3 0.0018
384 NADH-ubiquinone oxidoreductase chain 6 MT-ND6 0.0018
607 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NDUFA2 0.0018
300 NADH-ubiquinone oxidoreductase chain 4L MT-ND4L 0.0018
656 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 0.0018
582 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NDUFA13 0.0018
746 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NDUFB8 0.0018
99 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NDUFS5 0.0018
270 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NDUFB5 0.0018
30 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NDUFV3 0.0018
446 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NDUFA7 0.0018
525 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NDUFA5 0.0018
219 NADH-ubiquinone oxidoreductase chain 3 MT-ND3 0.0018
104 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NDUFS6 0.0018
236 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NDUFA6 0.0018
417 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NDUFB6 0.0018
324 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NDUFB4 0.0018
335 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NDUFA9 0.0018
568 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NDUFB7 0.0018
152 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NDUFV2 0.0018
829 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NDUFA12 0.0018
107 C-4 methylsterol oxidase SC4MOL 0.0018
628 Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial PDHA1 0.0018
405 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NDUFA8 0.0018
272 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NDUFB10 0.0018
372 Estradiol 17-beta-dehydrogenase 3 HSD17B3 0.0018
555 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 0.0018
711 UDP-glucose 6-dehydrogenase UGDH 0.0018
3672 UDP-glucose 6-dehydrogenase hasB 0.0018
729 GDP-L-fucose synthetase TSTA3 0.0018
3463 GDP-L-fucose synthetase fcl 0.0018
487 Aldo-keto reductase family 1 member C4 AKR1C4 0.0018
196 D-beta-hydroxybutyrate dehydrogenase, mitochondrial BDH1 0.0018
721 NADH-ubiquinone oxidoreductase chain 2 MT-ND2 0.0018
91 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NDUFA10 0.0018
14 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial IDH3A 0.0018
216 Aldehyde dehydrogenase 3B2 ALDH3B2 0.0018
616 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial IDH3B 0.0018
9 Estradiol 17-beta-dehydrogenase 2 HSD17B2 0.0018
671 Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial PDHA2 0.0018
848 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial IDH3G 0.0018
231 Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic GPD1 0.0018
539 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NDUFV1 0.0018
496 Aldehyde dehydrogenase 3B1 ALDH3B1 0.0018
609 15-hydroxyprostaglandin dehydrogenase [NAD+] HPGD 0.0018
34 7-dehydrocholesterol reductase DHCR7 0.0018
662 Fatty aldehyde dehydrogenase ALDH3A2 0.0018
149 Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 0.0018
531 Aldehyde dehydrogenase X, mitochondrial ALDH1B1 0.0018
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.0018
3726 D-3-phosphoglycerate dehydrogenase serA 0.0018
4291 D-3-phosphoglycerate dehydrogenase serA 0.0018
258 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial ALDH6A1 0.0018
644 Heme oxygenase 2 HMOX2 0.0018
4982 Heme oxygenase 2 pbsA2 0.0018
271 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial ALDH4A1 0.0018
167 L-lactate dehydrogenase C chain LDHC 0.0018
326 L-lactate dehydrogenase A-like 6A LDHAL6A 0.0018
141 3-hydroxyisobutyrate dehydrogenase, mitochondrial HIBADH 0.0018
637 NADH-ubiquinone oxidoreductase chain 5 MT-ND5 0.0018
206 3-keto-steroid reductase HSD17B7 0.0018
50 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating NSDHL 0.0018
112 L-lactate dehydrogenase A-like 6B LDHAL6B 0.0018
145 Corticosteroid 11-beta-dehydrogenase isozyme 2 HSD11B2 0.0018
643 Peroxisomal bifunctional enzyme EHHADH 0.0018
548 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NDUFS1 0.0018
288 Trifunctional enzyme subunit alpha, mitochondrial HADHA 0.0018
393 GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase H6PD 0.0018
608 NADH-ubiquinone oxidoreductase chain 4 MT-ND4 0.0018
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0017
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0017
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.0017
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.0017
857 Malate dehydrogenase, mitochondrial MDH2 0.0017
328 Sorbitol dehydrogenase SORD 0.0017
597 Dihydropteridine reductase QDPR 0.0017
363 NADP-dependent malic enzyme, mitochondrial ME3 0.0017
396 Alcohol dehydrogenase 4 ADH4 0.0017
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0017
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.0016
74 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial DLAT 0.0016
12 Alcohol dehydrogenase class 3 ADH5 0.0016
77 L-lactate dehydrogenase B chain LDHB 0.0016
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0016
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0016
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0016
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0016
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0016
473 L-lactate dehydrogenase A chain LDHA 0.0016
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0015
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0015
6026 Alcohol dehydrogenase 6 ADH6 0.0015
13 Aminomethyltransferase, mitochondrial AMT 0.0015
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0015
296 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial MTHFD2 0.0014
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0014
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0014
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0014
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0014
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0014
626 Cysteine dioxygenase type 1 CDO1 0.0014
627 11-cis retinol dehydrogenase RDH5 0.0014
640 Aldehyde dehydrogenase 1A3 ALDH1A3 0.0014
248 Pyrroline-5-carboxylate reductase 1 PYCR1 0.0014
802 Pyrroline-5-carboxylate reductase 2 PYCR2 0.0014
110 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.0014
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0014
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0014
569 Retinal dehydrogenase 2 ALDH1A2 0.0013
611 Retinal dehydrogenase 1 ALDH1A1 0.0013
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0013
251 Alcohol dehydrogenase 1A ADH1A 0.0013
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0013
57 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I HSD3B1 0.0013
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0012
714 Glutathione reductase, mitochondrial GSR 0.0012
279 Tyrosinase TYR 0.0012
380 Cytochrome P450 17A1 CYP17A1 0.0012
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0012
517 Alcohol dehydrogenase 1C ADH1C 0.0012
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0011
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.001
468 Cytochrome P450 4A11 CYP4A11 0.001
6020 Aldehyde oxidase AOX1 0.001
3947 Xanthine dehydrogenase/oxidase XDH 0.0009
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