DT-Web

DB04122 - Beta-D-Glucose-6-Phosphate


Identification
Name Beta-D-Glucose-6-Phosphate
Accession Number DB04122 (EXPT00684)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 260.1358
Groups experimental
Monoisotopic Weight 260.029718526
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Glucose-6-phosphate 1-dehydrogenase
Name Glucose-6-phosphate 1-dehydrogenase
Gene Name zwf
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.0085

Predictions


Id Partner name Gene Name Score
2675 Pteridine reductase 1 PTR1 0.0783
2826 Glucose--fructose oxidoreductase gfo 0.0739
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0637
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0632
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0567
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0119
646 Malate dehydrogenase, cytoplasmic MDH1 0.0105
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.0103
5330 General stress protein 69 yhdN 0.0097
5342 NADH-dependent butanol dehydrogenase, putative TM_0820 0.0097
5346 Oxidoreductase, aldo/keto reductase family TM_1009 0.0097
5332 MtdA bifunctional protein mtdA 0.0097
3772 3-oxoacyl-[acyl-carrier-protein] reductase fabG 0.0097
4403 Protein iolS iolS 0.0097
5333 Alcohol dehydrogenase, iron-containing TM_0920 0.0097
5322 Oxidoreductase ydhF ydhF 0.0097
5326 Oxidoreductase, short chain dehydrogenase/reductase family TM_0441 0.0097
5157 Dehydrogenase/reductase SDR family member 11 DHRS11 0.0097
3778 NAD(P) transhydrogenase subunit beta pntB 0.0097
5343 NADP-dependent fatty aldehyde dehydrogenase aldH 0.0097
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0091
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.0085
2636 Shikimate dehydrogenase aroE 0.0084
3515 Shikimate dehydrogenase aroE 0.0084
5328 Prostaglandin F synthase Tb11.02.2310 0.0084
2375 ADP-L-glycero-D-manno-heptose-6-epimerase hldD 0.0084
729 GDP-L-fucose synthetase TSTA3 0.0084
3463 GDP-L-fucose synthetase fcl 0.0084
3446 NADP-dependent alcohol dehydrogenase adh 0.0084
2305 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 0.0084
989 L-xylulose reductase DCXR 0.0084
5073 Ferredoxin--NADP reductase petH 0.0084
5076 Ferredoxin--NADP reductase fpr 0.0084
5119 Ferredoxin--NADP reductase petH 0.0084
5121 Ferredoxin--NADP reductase fpr 0.0084
4628 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase gapN 0.0084
4582 Putative pteridine reductase 2 ptr2 0.0084
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0084
2286 Isocitrate dehydrogenase [NADP] icd 0.0084
2302 Isocitrate dehydrogenase [NADP] icd 0.0084
2771 Isocitrate dehydrogenase [NADP] icd 0.0084
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0081
444 Alcohol dehydrogenase 1B ADH1B 0.008
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.0079
666 NADP-dependent malic enzyme ME1 0.0079
4531 Putative ketoacyl reductase actIII 0.0078
6297 Prostaglandin reductase 1 PTGR1 0.0078
3062 Aspartate-semialdehyde dehydrogenase asd 0.0078
6862 Aldo-keto reductase family 1 member B10 AKR1B10 0.0078
11 NAD(P) transhydrogenase, mitochondrial NNT 0.0074
1124 Sepiapterin reductase SPR 0.0073
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0073
2159 Quinone oxidoreductase CRYZ 0.0072
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0066
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0064
654 Flavin reductase BLVRB 0.0062
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0059
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0056
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0053
76 Nitric-oxide synthase, brain NOS1 0.0049
822 Aldose reductase AKR1B1 0.0049
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0048
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0048
4120 NADPH--cytochrome P450 reductase POR 0.0047
365 Dihydrofolate reductase DHFR 0.0046
2381 Dihydrofolate reductase DFR1 0.0046
2833 Dihydrofolate reductase Not Available 0.0046
2931 Dihydrofolate reductase folA 0.0046
3544 Dihydrofolate reductase folA 0.0046
3682 Dihydrofolate reductase folA 0.0046
6642 Dihydrofolate reductase folA 0.0046
6756 Dihydrofolate reductase dfrA 0.0046
4449 ADP-ribosyltransferase Not Available 0.004
4435 L-aspartate dehydrogenase nadX 0.004
4428 Redox-sensing transcriptional repressor rex rex 0.004
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.004
3726 D-3-phosphoglycerate dehydrogenase serA 0.004
4291 D-3-phosphoglycerate dehydrogenase serA 0.004
4495 3-oxoacyl-(Acyl carrier protein) reductase TM_1169 0.004
3735 NAD(P) transhydrogenase subunit alpha part 1 pntAA 0.004
4500 L-lactate dehydrogenase 2 ldh2 0.004
4446 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase Not Available 0.004
4472 Glucose 1-dehydrogenase Not Available 0.004
4423 Levodione reductase lvr 0.004
4505 Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase bphB 0.004
4507 Alanine dehydrogenase ald 0.004
4443 Quinate/shikimate dehydrogenase ydiB 0.004
4456 Inorganic polyphosphate/ATP-NAD kinase ppnK 0.004
4448 L-2-hydroxyisocaproate dehydrogenase Not Available 0.004
4447 Hypothetical protein yhfP yhfP 0.004
4336 Glyceraldehyde 3-phosphate dehydrogenase Not Available 0.004
4436 Glyceraldehyde 3-phosphate dehydrogenase tthHB8IM 0.004
3381 Alcohol dehydrogenase Not Available 0.004
4508 Alcohol dehydrogenase adhA 0.004
4414 Dehydrogenase TT_P0035 0.004
2350 3-isopropylmalate dehydrogenase leuB 0.004
3092 3-isopropylmalate dehydrogenase leuB 0.004
4471 CDP-D-glucose-4,6-dehydratase ascB 0.004
4418 AGR_L_3209p AGR_L_3209 0.004
4475 Hypothetical protein Rv0046c/MT0052 ino1 0.004
4455 Glycerol dehydrogenase gldA 0.004
4497 Benzyl alcohol dehydrogenase xylB 0.004
4506 Myo-inositol-1-phosphate synthase-related protein TM_1419 0.004
4466 Glutathione-independent formaldehyde dehydrogenase fdhA 0.004
4502 Formate dehydrogenase Not Available 0.004
4487 Transcriptional regulator nadR nadR 0.004
3729 Citrate synthase gltA 0.004
4575 Citrate synthase cit 0.004
4580 Citrate synthase gltA 0.004
4451 Vip2Ac vip2Ac 0.004
4467 Alpha-glucosidase, putative TM_0752 0.004
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0034
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0034
3401 D-2-hydroxyisocaproate dehydrogenase Not Available 0.0034
4427 TDP-glucose-4,6-dehydratase desIV 0.0034
4498 Ornithine cyclodeaminase PP3533 0.0034
6698 Dehydrogenase/reductase SDR family member 4-like 2 DHRS4L2 0.0034
3177 dTDP-glucose 4,6-dehydratase rfbB 0.0034
4499 dTDP-glucose 4,6-dehydratase rmlB 0.0034
3598 dTDP-4-dehydrorhamnose reductase rfbD 0.0034
4503 NADPH-flavin oxidoreductase frp 0.0034
3615 Dihydrodipicolinate reductase dapB 0.0034
3618 Dihydrodipicolinate reductase dapB 0.0034
4462 Dihydrodipicolinate reductase dapB 0.0034
4482 UDP-galactose 4-epimerase galE 0.0034
2831 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase Not Available 0.0034
3059 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase fabG3 0.0034
3671 7-alpha-hydroxysteroid dehydrogenase hdhA 0.0034
2336 2,3-diketo-L-gulonate reductase dlgD 0.0034
2538 6-phospho-beta-glucosidase bglT bglT 0.0034
4486 Phenol 2-hydroxylase component B pheA2 0.0034
1199 GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 ART1 0.0034
126 D-lactate dehydrogenase dld 0.0034
3545 D-lactate dehydrogenase Not Available 0.0034
4510 D-lactate dehydrogenase ldhA 0.0034
3081 3-dehydroquinate synthase aroB 0.0034
2018 Deoxyhypusine synthase DHPS 0.0034
2424 L-lactate dehydrogenase ldh 0.0034
2641 L-lactate dehydrogenase Not Available 0.0034
4437 L-lactate dehydrogenase ldh 0.0034
4442 L-lactate dehydrogenase ldh 0.0034
4439 Ferredoxin reductase bphA4 0.0034
4496 C-terminal-binding protein 1 CTBP1 0.0034
2393 Maltose-6'-phosphate glucosidase glvA 0.0034
4450 Iota toxin component Ia Not Available 0.0034
4509 Acetoin(diacetyl) reductase budC 0.0034
4477 Dihydrolipoyl dehydrogenase lpdV 0.0034
5077 Dihydrolipoyl dehydrogenase Not Available 0.0034
5117 Dihydrolipoyl dehydrogenase lpd 0.0034
2881 Gamma-aminobutyraldehyde dehydrogenase prr 0.0034
2591 Urocanate hydratase hutU 0.0034
2507 Diphtheria toxin Not Available 0.0034
2967 CDP-paratose 2-epimerase rfbE 0.0034
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0032
816 Biliverdin reductase A BLVRA 0.0032
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0032
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0032
2683 Mono-ADP-ribosyltransferase C3 C3 0.0032
711 UDP-glucose 6-dehydrogenase UGDH 0.0032
3672 UDP-glucose 6-dehydrogenase hasB 0.0032
3296 Nicotinamide mononucleotide adenylyltransferase 1 NMNAT1 0.0032
3367 GDP-mannose 6-dehydrogenase algD 0.0032
3736 Glyceraldehyde-3-phosphate dehydrogenase A gapA 0.0032
4504 WbpP Not Available 0.0032
2799 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal Not Available 0.0032
4440 NADH peroxidase npr 0.0032
4318 Siroheme synthase cysG 0.0032
4343 Alpha-glucosidase aglA 0.0032
396 Alcohol dehydrogenase 4 ADH4 0.003
597 Dihydropteridine reductase QDPR 0.003
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.003
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.003
328 Sorbitol dehydrogenase SORD 0.003
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.003
363 NADP-dependent malic enzyme, mitochondrial ME3 0.003
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.003
3191 Histidinol dehydrogenase hisD 0.003
3333 Nicotinamide mononucleotide adenylyltransferase 3 NMNAT3 0.003
2434 NH(3)-dependent NAD(+) synthetase nadE 0.003
2910 NH(3)-dependent NAD(+) synthetase nadE 0.003
3217 NH(3)-dependent NAD(+) synthetase nadE 0.003
2617 Nitric oxide synthase oxygenase nos 0.003
2701 Nitric oxide synthase oxygenase nos 0.003
3070 Adenosylhomocysteinase AHCY 0.003
4424 Adenosylhomocysteinase PFE1050w 0.003
6278 Adenosylhomocysteinase ahcY 0.003
63 Malate dehydrogenase mdh 0.0029
2329 Malate dehydrogenase mdh 0.0029
3445 Malate dehydrogenase mdh 0.0029
4420 Malate dehydrogenase mdh 0.0029
4438 Malate dehydrogenase mdh 0.0029
4476 Mannitol dehydrogenase mtlD 0.0029
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.0029
12 Alcohol dehydrogenase class 3 ADH5 0.0029
77 L-lactate dehydrogenase B chain LDHB 0.0029
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0029
327 Glutathione reductase gor 0.0029
5110 Glutathione reductase GR2 0.0029
473 L-lactate dehydrogenase A chain LDHA 0.0028
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0028
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0028
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0028
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0028
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0028
4491 DNA ligase, NAD-dependent ligA 0.0028
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0027
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0027
2762 UDP-glucose 4-epimerase GALE 0.0027
3461 UDP-glucose 4-epimerase galE 0.0027
569 Retinal dehydrogenase 2 ALDH1A2 0.0024
611 Retinal dehydrogenase 1 ALDH1A1 0.0024
251 Alcohol dehydrogenase 1A ADH1A 0.0024
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0024
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0024
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0022
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0022
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0022
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0022
714 Glutathione reductase, mitochondrial GSR 0.0022
517 Alcohol dehydrogenase 1C ADH1C 0.0021
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0021
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