DT-Web

DB03273 - 3'-Oxo-Adenosine


Identification
Name 3'-Oxo-Adenosine
Accession Number DB03273 (EXPT00442)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 265.2254
Groups experimental
Monoisotopic Weight 265.081103865
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Adenosylhomocysteinase
Name Adenosylhomocysteinase
Gene Name AHCY
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.5035

Predictions


Id Partner name Gene Name Score
4424 Adenosylhomocysteinase PFE1050w 1.5035
6278 Adenosylhomocysteinase ahcY 1.5035
4423 Levodione reductase lvr 0.004
4428 Redox-sensing transcriptional repressor rex rex 0.004
4507 Alanine dehydrogenase ald 0.004
4495 3-oxoacyl-(Acyl carrier protein) reductase TM_1169 0.004
4446 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase Not Available 0.004
4472 Glucose 1-dehydrogenase Not Available 0.004
4505 Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase bphB 0.004
4443 Quinate/shikimate dehydrogenase ydiB 0.004
4456 Inorganic polyphosphate/ATP-NAD kinase ppnK 0.004
4448 L-2-hydroxyisocaproate dehydrogenase Not Available 0.004
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.004
3726 D-3-phosphoglycerate dehydrogenase serA 0.004
4291 D-3-phosphoglycerate dehydrogenase serA 0.004
4447 Hypothetical protein yhfP yhfP 0.004
4336 Glyceraldehyde 3-phosphate dehydrogenase Not Available 0.004
4436 Glyceraldehyde 3-phosphate dehydrogenase tthHB8IM 0.004
4414 Dehydrogenase TT_P0035 0.004
2350 3-isopropylmalate dehydrogenase leuB 0.004
3092 3-isopropylmalate dehydrogenase leuB 0.004
4471 CDP-D-glucose-4,6-dehydratase ascB 0.004
4418 AGR_L_3209p AGR_L_3209 0.004
4475 Hypothetical protein Rv0046c/MT0052 ino1 0.004
4455 Glycerol dehydrogenase gldA 0.004
4497 Benzyl alcohol dehydrogenase xylB 0.004
4449 ADP-ribosyltransferase Not Available 0.004
3735 NAD(P) transhydrogenase subunit alpha part 1 pntAA 0.004
4466 Glutathione-independent formaldehyde dehydrogenase fdhA 0.004
4502 Formate dehydrogenase Not Available 0.004
4500 L-lactate dehydrogenase 2 ldh2 0.004
4435 L-aspartate dehydrogenase nadX 0.004
4451 Vip2Ac vip2Ac 0.004
4467 Alpha-glucosidase, putative TM_0752 0.004
3729 Citrate synthase gltA 0.004
4575 Citrate synthase cit 0.004
4580 Citrate synthase gltA 0.004
3381 Alcohol dehydrogenase Not Available 0.004
4508 Alcohol dehydrogenase adhA 0.004
4506 Myo-inositol-1-phosphate synthase-related protein TM_1419 0.004
4487 Transcriptional regulator nadR nadR 0.004
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0034
3598 dTDP-4-dehydrorhamnose reductase rfbD 0.0034
4486 Phenol 2-hydroxylase component B pheA2 0.0034
3177 dTDP-glucose 4,6-dehydratase rfbB 0.0034
4499 dTDP-glucose 4,6-dehydratase rmlB 0.0034
4503 NADPH-flavin oxidoreductase frp 0.0034
3615 Dihydrodipicolinate reductase dapB 0.0034
3618 Dihydrodipicolinate reductase dapB 0.0034
4462 Dihydrodipicolinate reductase dapB 0.0034
4482 UDP-galactose 4-epimerase galE 0.0034
2831 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase Not Available 0.0034
3059 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase fabG3 0.0034
4509 Acetoin(diacetyl) reductase budC 0.0034
3401 D-2-hydroxyisocaproate dehydrogenase Not Available 0.0034
126 D-lactate dehydrogenase dld 0.0034
3545 D-lactate dehydrogenase Not Available 0.0034
4510 D-lactate dehydrogenase ldhA 0.0034
2881 Gamma-aminobutyraldehyde dehydrogenase prr 0.0034
2424 L-lactate dehydrogenase ldh 0.0034
2641 L-lactate dehydrogenase Not Available 0.0034
4437 L-lactate dehydrogenase ldh 0.0034
4442 L-lactate dehydrogenase ldh 0.0034
1199 GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 ART1 0.0034
2336 2,3-diketo-L-gulonate reductase dlgD 0.0034
4427 TDP-glucose-4,6-dehydratase desIV 0.0034
2967 CDP-paratose 2-epimerase rfbE 0.0034
4498 Ornithine cyclodeaminase PP3533 0.0034
3081 3-dehydroquinate synthase aroB 0.0034
2018 Deoxyhypusine synthase DHPS 0.0034
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0034
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0034
6698 Dehydrogenase/reductase SDR family member 4-like 2 DHRS4L2 0.0034
4439 Ferredoxin reductase bphA4 0.0034
2538 6-phospho-beta-glucosidase bglT bglT 0.0034
4496 C-terminal-binding protein 1 CTBP1 0.0034
2393 Maltose-6'-phosphate glucosidase glvA 0.0034
3671 7-alpha-hydroxysteroid dehydrogenase hdhA 0.0034
4450 Iota toxin component Ia Not Available 0.0034
4477 Dihydrolipoyl dehydrogenase lpdV 0.0034
5077 Dihydrolipoyl dehydrogenase Not Available 0.0034
5117 Dihydrolipoyl dehydrogenase lpd 0.0034
2591 Urocanate hydratase hutU 0.0034
2507 Diphtheria toxin Not Available 0.0034
3736 Glyceraldehyde-3-phosphate dehydrogenase A gapA 0.0032
2799 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal Not Available 0.0032
2683 Mono-ADP-ribosyltransferase C3 C3 0.0032
3296 Nicotinamide mononucleotide adenylyltransferase 1 NMNAT1 0.0032
711 UDP-glucose 6-dehydrogenase UGDH 0.0032
3672 UDP-glucose 6-dehydrogenase hasB 0.0032
4440 NADH peroxidase npr 0.0032
4504 WbpP Not Available 0.0032
3367 GDP-mannose 6-dehydrogenase algD 0.0032
4318 Siroheme synthase cysG 0.0032
4343 Alpha-glucosidase aglA 0.0032
816 Biliverdin reductase A BLVRA 0.0031
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0031
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0031
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0031
2434 NH(3)-dependent NAD(+) synthetase nadE 0.003
2910 NH(3)-dependent NAD(+) synthetase nadE 0.003
3217 NH(3)-dependent NAD(+) synthetase nadE 0.003
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.003
2617 Nitric oxide synthase oxygenase nos 0.003
2701 Nitric oxide synthase oxygenase nos 0.003
2826 Glucose--fructose oxidoreductase gfo 0.003
3191 Histidinol dehydrogenase hisD 0.003
3333 Nicotinamide mononucleotide adenylyltransferase 3 NMNAT3 0.003
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.003
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.003
597 Dihydropteridine reductase QDPR 0.003
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.003
4476 Mannitol dehydrogenase mtlD 0.003
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.003
646 Malate dehydrogenase, cytoplasmic MDH1 0.003
328 Sorbitol dehydrogenase SORD 0.003
396 Alcohol dehydrogenase 4 ADH4 0.003
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.003
363 NADP-dependent malic enzyme, mitochondrial ME3 0.003
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.003
63 Malate dehydrogenase mdh 0.0029
2329 Malate dehydrogenase mdh 0.0029
3445 Malate dehydrogenase mdh 0.0029
4420 Malate dehydrogenase mdh 0.0029
4438 Malate dehydrogenase mdh 0.0029
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0029
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0029
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0029
327 Glutathione reductase gor 0.0028
5110 Glutathione reductase GR2 0.0028
12 Alcohol dehydrogenase class 3 ADH5 0.0028
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.0028
77 L-lactate dehydrogenase B chain LDHB 0.0028
2286 Isocitrate dehydrogenase [NADP] icd 0.0028
2302 Isocitrate dehydrogenase [NADP] icd 0.0028
2771 Isocitrate dehydrogenase [NADP] icd 0.0028
4491 DNA ligase, NAD-dependent ligA 0.0028
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0027
473 L-lactate dehydrogenase A chain LDHA 0.0027
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0027
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0027
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0027
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0027
2762 UDP-glucose 4-epimerase GALE 0.0027
3461 UDP-glucose 4-epimerase galE 0.0027
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0027
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0027
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0026
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0024
611 Retinal dehydrogenase 1 ALDH1A1 0.0024
251 Alcohol dehydrogenase 1A ADH1A 0.0024
569 Retinal dehydrogenase 2 ALDH1A2 0.0024
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0024
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0023
444 Alcohol dehydrogenase 1B ADH1B 0.0023
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0022
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0022
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0022
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0022
714 Glutathione reductase, mitochondrial GSR 0.0022
517 Alcohol dehydrogenase 1C ADH1C 0.0021
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0021
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