DT-Web

DB02926 - 2-Oxo-Glutaric Acid


Identification
Name 2-Oxo-Glutaric Acid
Accession Number DB02926 (DB03806, EXPT00137)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 146.0981
Groups experimental
Monoisotopic Weight 146.021523302
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Aspartate aminotransferase
Name Aspartate aminotransferase
Gene Name aspC
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.5051
CarC
Name CarC
Gene Name carC
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.676
Ferredoxin-dependent glutamate synthase 2
Name Ferredoxin-dependent glutamate synthase 2
Gene Name gltS
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.6949

Predictions


Id Partner name Gene Name Score
2671 Aspartate aminotransferase aspC 1.5051
5490 Aspartate aminotransferase Not Available 1.5051
2537 Aromatic-amino-acid aminotransferase tyrB 0.1082
4802 L-cysteine/cystine lyase C-DES c-des 0.0586
4584 Aminotransferase Not Available 0.0583
3526 Pseudomonalisin pcp 0.0538
4674 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase cumD 0.0453
894 Alanine racemase alr 0.0446
2453 Alanine racemase alr 0.0446
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.0387
2823 Trypanothione reductase TPR 0.0304
5353 Glutamate decarboxylase alpha gadA 0.0286
586 Aspartate aminotransferase, cytoplasmic GOT1 0.0232
3688 Branched-chain-amino-acid aminotransferase ilvE 0.0218
5492 Cystathionine gamma-synthase metB 0.0185
5491 Methionine gamma-lyase mdeA 0.0185
763 Tyrosine aminotransferase TAT 0.0185
5493 Tyrosine aminotransferase Not Available 0.0185
5201 FMN-binding protein DvMF_2023 0.0185
5197 Trp repressor binding protein WrbA, putative DR_A0214 0.0185
5175 Hypothetical protein SMU.260 SMU_260 0.0185
3293 Flavodoxin Not Available 0.0185
4614 Flavodoxin DVU_2680 0.0185
5172 Flavodoxin isiB 0.0185
5173 Flavodoxin isiB 0.0185
5182 Flavodoxin fldA 0.0185
5191 Morphinone reductase morB 0.0184
5181 Hypothetical protein yhdA azr 0.0184
5198 Flavodoxin-1 fldA 0.0184
5170 Epidermin decarboxylase epiD 0.0184
5179 Probable aromatic acid decarboxylase pad1 0.0184
5202 Nitroreductase family protein BC_1844 0.0184
5200 NADH dehydrogenase nox 0.0184
2586 Isopentenyl-diphosphate Delta-isomerase idi 0.0184
5187 Isopentenyl-diphosphate delta-isomerase fni 0.0184
5199 Isopentenyl-diphosphate delta-isomerase fni 0.0184
5131 PhzG phzG 0.0184
5193 Phenazine biosynthesis protein phzG phzG 0.0184
5178 Protein nrdI nrdI 0.0184
4037 Hypothetical protein GPX1 0.0184
4297 Hypothetical protein SP_1951 0.0184
4521 Hypothetical protein BC_2969 0.0184
4540 Hypothetical protein TM_1070 0.0184
4555 Hypothetical protein MT1739 0.0184
4569 Hypothetical protein mshD 0.0184
4578 Hypothetical protein PA3270 0.0184
4747 Hypothetical protein PA3967 0.0184
5177 Hypothetical protein TM_0096 0.0184
5194 Hypothetical protein PA1204 0.0184
5240 Hypothetical protein Rv2991 0.0184
5370 Hypothetical protein TM_1158 0.0184
5710 Hypothetical protein Tb927.5.1360 0.0184
4405 Nitric oxide reductase fprA 0.0184
5190 Rubredoxin-oxygen oxidoreductase roo 0.0184
4407 FMN-dependent NADH-azoreductase azoR 0.0161
5169 FMN-dependent NADH-azoreductase azoR 0.0161
5206 Phosphopantothenoylcysteine decarboxylase PPCDC 0.0161
3766 Pyridoxamine 5'-phosphate oxidase pdxH 0.0161
4503 NADPH-flavin oxidoreductase frp 0.0161
3507 Chorismate synthase aroC 0.0161
5171 Chorismate synthase aroC 0.0161
5176 YtnJ moxC 0.0161
3680 Dihydroorotate dehydrogenase A pyrDA 0.0161
5189 Trimethylamine dehydrogenase tmd 0.0161
4823 L-allo-threonine aldolase TM_1744 0.0148
2775 Dihydroorotate dehydrogenase pyrD 0.0148
6608 Serine/threonine-protein kinase Sgk1 SGK1 0.0148
2758 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase bioA 0.0147
408 Riboflavin kinase RFK 0.0147
685 Oxygen-insensitive NADPH nitroreductase nfsA 0.0145
6945 Oxygen-insensitive NADPH nitroreductase rdxA 0.0145
5180 L(+)-mandelate dehydrogenase mdlB 0.014
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.014
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.014
2261 Major NAD(P)H-flavin oxidoreductase Not Available 0.0139
203 Pyridoxine-5'-phosphate oxidase PNPO 0.0133
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0129
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0129
4284 Pentaerythritol tetranitrate reductase onr 0.0125
654 Flavin reductase BLVRB 0.0122
301 Kynurenine--oxoglutarate transaminase 1 CCBL1 0.0118
6268 Hydroxyacid oxidase 1 HAO1 0.0116
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0114
449 Ornithine decarboxylase ODC1 0.0113
349 Serine--pyruvate aminotransferase AGXT 0.0105
1024 Solute carrier family 22 member 11 SLC22A11 0.01
4120 NADPH--cytochrome P450 reductase POR 0.0098
6143 Solute carrier family 22 member 7 SLC22A7 0.0097
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0095
76 Nitric-oxide synthase, brain NOS1 0.0095
6142 Solute carrier family 22 member 8 SLC22A8 0.0088
1152 Glycogen phosphorylase, muscle form PYGM 0.0083
1729 Solute carrier family 22 member 6 SLC22A6 0.008
↑