DT-Web

DB00865 - Benzphetamine


Identification
Name Benzphetamine
Accession Number DB00865 (APRD00759)
Type small molecule
Description A sympathomimetic agent with properties similar to dextroamphetamine. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 239.3553
Groups illicit
Monoisotopic Weight 239.167399677
Pharmacology
Indication For the management of exogenous obesity as a short term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction
Mechanism of action Although the mechanism of action of the sympathomimetic appetite suppressants in the treatment of obesity is not fully known, these medications have pharmacological effects similar to those of amphetamines. Amphetamine and related sympathomimetic medications (such as benzphetamine) are thought to stimulate the release of norepinephrine and/or dopamine from storage sites in nerve terminals in the lateral hypothalamic feeding center, thereby producing a decrease in appetite. This release is mediated by the binding of benzphetamine to centrally located adrenergic receptors.
Absorption Readily absorbed from the gastro-intestinal tract and buccal mucosa. It Is resistant to metabolism by monoamine oxidase.
Protein binding 75-99%
Biotransformation Hepatic. Benzphetamine's metabolites include amphetamine and methamphetamine.
Route of elimination Not Available
Toxicity LD50=160 mg/kg (orally in rats). Acute overdosage may result in restlessness, tremor, tachypnea, confusion, assaultiveness, and panic states.
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions
Drug Mechanism of interaction
Chlorpromazine Antipsychotics may diminish the stimulatory effect of Amphetamines. Monitor effectiveness of amphetamine therapy when altering concurrent antipsychotic therapy as antipsychotic agents may impair the stimulatory effect of amphetamines.
Fluoxetine Amphetamines may enhance the adverse/toxic effect of Serotonin Modulators. The risk of serotonin syndrome may be increased. Monitor patients closely for signs and symptoms of serotonin syndrome (e.g., agitation, tremor, tachycardia, etc.) when using amphetamines and serotonin modulators in combination.
Fluphenazine Antipsychotics may diminish the stimulatory effect of Amphetamines. Monitor effectiveness of amphetamine therapy when altering concurrent antipsychotic therapy as antipsychotic agents may impair the stimulatory effect of amphetamines.
Fluvoxamine Amphetamines may enhance the adverse/toxic effect of Serotonin Modulators. The risk of serotonin syndrome may be increased. Monitor patients closely for signs and symptoms of serotonin syndrome (e.g., agitation, tremor, tachycardia, etc.) when using amphetamines and serotonin modulators in combination.
Guanethidine Benzphetamine may decrease the effect of guanethidine.
Isocarboxazid MAO Inhibitors may enhance the hypertensive effect of Amphetamines. Concomitant use of amphetamines and monoamine oxidase inhibitors (MAOI) should be avoided. If used concomitantly, careful monitoring of blood pressure must occur. It may take up to 2 weeks after the discontinuation of an MAOI for the effects to dissipate enough to afford safety to the administration of interacting agents.
Mesoridazine Antipsychotics may diminish the stimulatory effect of Amphetamines. Monitor effectiveness of amphetamine therapy when altering concurrent antipsychotic therapy as antipsychotic agents may impair the stimulatory effect of amphetamines.
Methotrimeprazine Antipsychotics may diminish the stimulatory effect of Amphetamines. Monitor effectiveness of amphetamine therapy when altering concurrent antipsychotic therapy as antipsychotic agents may impair the stimulatory effect of amphetamines.
Paroxetine Amphetamines may enhance the adverse/toxic effect of Serotonin Modulators. The risk of serotonin syndrome may be increased. Monitor patients closely for signs and symptoms of serotonin syndrome (e.g., agitation, tremor, tachycardia, etc.) when using amphetamines and serotonin modulators in combination.
Perphenazine Antipsychotics may diminish the stimulatory effect of Amphetamines. Monitor effectiveness of amphetamine therapy when altering concurrent antipsychotic therapy as antipsychotic agents may impair the stimulatory effect of amphetamines.
Phenelzine MAO Inhibitors may enhance the hypertensive effect of Amphetamines. Concomitant use of amphetamines and monoamine oxidase inhibitors (MAOI) should be avoided. If used concomitantly, careful monitoring of blood pressure must occur. It may take up to 2 weeks after the discontinuation of an MAOI for the effects to dissipate enough to afford safety to the administration of interacting agents.
Prochlorperazine Antipsychotics may diminish the stimulatory effect of Amphetamines. Monitor effectiveness of amphetamine therapy when altering concurrent antipsychotic therapy as antipsychotic agents may impair the stimulatory effect of amphetamines.
Promethazine Antipsychotics may diminish the stimulatory effect of Amphetamines. Monitor effectiveness of amphetamine therapy when altering concurrent antipsychotic therapy as antipsychotic agents may impair the stimulatory effect of amphetamines.
Propericiazine Antipsychotics may diminish the stimulatory effect of Amphetamines. Monitor effectiveness of amphetamine therapy when altering concurrent antipsychotic therapy as antipsychotic agents may impair the stimulatory effect of amphetamines.
Rasagiline MAO Inhibitors may enhance the hypertensive effect of Amphetamines. Concomitant use of amphetamines and monoamine oxidase inhibitors (MAOI) should be avoided. If used concomitantly, careful monitoring of blood pressure must occur. It may take up to 2 weeks after the discontinuation of an MAOI for the effects to dissipate enough to afford safety to the administration of interacting agents.
Sodium bicarbonate Alkalinizing agents such as sodium bicarbonate may decrease the excretion of amphetamines like benzphetamine. Increased clinical effects and/or toxicity may occur. Therapy modification should be considered.
Telithromycin Telithromycin may reduce clearance of Benzphetamine. Consider alternate therapy or monitor for changes in the therapeutic/adverse effects of Benzphetamine if Telithromycin is initiated, discontinued or dose changed.
Thioridazine Antipsychotics may diminish the stimulatory effect of Amphetamines. Monitor effectiveness of amphetamine therapy when altering concurrent antipsychotic therapy as antipsychotic agents may impair the stimulatory effect of amphetamines.
Tramadol Increased risk of serotonin syndrome. Monitor for symptoms of serotonin syndrome.
Trandolapril Benzphetamine may reduce the efficacy of Trandolapril.
Tranylcypromine The MAO inhibitor, Tranylcypromine, may increase the vasopressor effect of the amphetamine, Benzphetamine. Concomitant therapy should be avoided.
Trifluoperazine Antipsychotics may diminish the stimulatory effect of Amphetamines. Monitor effectiveness of amphetamine therapy when altering concurrent antipsychotic therapy as antipsychotic agents may impair the stimulatory effect of amphetamines.
Triprolidine Triprolidine may reduce the sedative effect of the antihistamine, Benzphetamine.
Voriconazole Voriconazole, a strong CYP3A4 inhibitor, may increase the serum concentration of benzphetamine by decreasing its metabolism. Monitor for changes in the therapeutic and adverse effects of benzphetamine if voriconazole is initiated, discontinued or dose changed.
Food Interactions Not Available

Targets


Synaptic vesicular amine transporter
Name Synaptic vesicular amine transporter
Gene Name SLC18A2
Pharmacological action yes
Actions inducer
References
  • Sulzer D, Chen TK, Lau YY, Kristensen H, Rayport S, Ewing A: Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport. J Neurosci. 1995 May;15(5 Pt 2):4102-8. - Pubmed
DTHybrid score 0.6153
Alpha-2A adrenergic receptor
Name Alpha-2A adrenergic receptor
Gene Name ADRA2A
Pharmacological action yes
Actions agonist
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.385
Alpha-1A adrenergic receptor
Name Alpha-1A adrenergic receptor
Gene Name ADRA1A
Pharmacological action yes
Actions agonist
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.4692
Sodium-dependent dopamine transporter
Name Sodium-dependent dopamine transporter
Gene Name SLC6A3
Pharmacological action unknown
Actions inhibitor
References
  • Sulzer D, Sonders MS, Poulsen NW, Galli A: Mechanisms of neurotransmitter release by amphetamines: a review. Prog Neurobiol. 2005 Apr;75(6):406-33. - Pubmed
  • Kahlig KM, Binda F, Khoshbouei H, Blakely RD, McMahon DG, Javitch JA, Galli A: Amphetamine induces dopamine efflux through a dopamine transporter channel. Proc Natl Acad Sci U S A. 2005 Mar 1;102(9):3495-500. Epub 2005 Feb 22. - Pubmed
DTHybrid score 0.4731

Enzymes


Cytochrome P450 3A4
Name Cytochrome P450 3A4
Gene Name CYP3A4
Actions substrate
References
  • -
  • Seree EJ, Pisano PJ, Placidi M, Rahmani R, Barra YA: Identification of the human and animal hepatic cytochromes P450 involved in clonazepam metabolism. Fundam Clin Pharmacol. 1993;7(2):69-75. - Pubmed
DTHybrid score 0.4131
Cytochrome P450 2B6
Name Cytochrome P450 2B6
Gene Name CYP2B6
Actions substrate
References
  • Bumpus NN, Sridar C, Kent UM, Hollenberg PF: The naturally occurring cytochrome P450 (P450) 2B6 K262R mutant of P450 2B6 exhibits alterations in substrate metabolism and inactivation. Drug Metab Dispos. 2005 Jun;33(6):795-802. Epub 2005 Mar 15. - Pubmed
  • Shebley M, Kent UM, Ballou DP, Hollenberg PF: Mechanistic analysis of the inactivation of cytochrome P450 2B6 by phencyclidine: effects on substrate binding, electron transfer, and uncoupling. Drug Metab Dispos. 2009 Apr;37(4):745-52. Epub 2009 Jan 14. - Pubmed
DTHybrid score 0.2539
NADPH--cytochrome P450 reductase
Name NADPH--cytochrome P450 reductase
Gene Name POR
Actions substrate
References
  • Kanaeva IP, Nikityuk OV, Davydov DR, Dedinskii IR, Koen YM, Kuznetsova GP, Skotselyas ED, Bachmanova GI, Archakov AI: Comparative study of monomeric reconstituted and membrane microsomal monooxygenase systems of the rabbit liver. II. Kinetic parameters of reductase and monooxygenase reactions. Arch Biochem Biophys. 1992 Nov 1;298(2):403-12. - Pubmed
  • Matsumoto T, Emi Y, Kawabata S, Omura T: Purification and characterization of three male-specific and one female-specific forms of cytochrome P-450 from rat liver microsomes. J Biochem (Tokyo). 1986 Nov;100(5):1359-71. - Pubmed
  • Kojima H, Takahashi K, Sakane F, Koyama J: Purification and characterization of NADPH-cytochrome c reductase from porcine polymorphonuclear leukocytes. J Biochem (Tokyo). 1987 Nov;102(5):1083-8. - Pubmed
  • Dutton DR, McMillen SK, Parkinson A: Purification of rat liver microsomal cytochrome P-450b without the use of nonionic detergent. J Biochem Toxicol. 1988 Summer;3:131-45. - Pubmed
  • Halpert JR, Miller NE, Gorsky LD: On the mechanism of the inactivation of the major phenobarbital-inducible isozyme of rat liver cytochrome P-450 by chloramphenicol. J Biol Chem. 1985 Jul 15;260(14):8397-403. - Pubmed
DTHybrid score 0.2434

Predictions


Id Partner name Gene Name Score
4119 Cytochrome P450 2D6 CYP2D6 0.2608
540 Sodium-dependent noradrenaline transporter SLC6A2 0.2563
824 Sodium-dependent serotonin transporter SLC6A4 0.1779
1588 Multidrug resistance protein 1 ABCB1 0.1619
632 Alpha-1B adrenergic receptor ADRA1B 0.1498
4200 Cytochrome P450 1A2 CYP1A2 0.1459
4757 Cytochrome P450 2C9 CYP2C9 0.1329
6016 Cytochrome P450 2C19 CYP2C19 0.1319
1636 Trace amine-associated receptor 1 TAAR1 0.1283
502 5-hydroxytryptamine 2A receptor HTR2A 0.1111
4118 Cytochrome P450 3A5 CYP3A5 0.1057
629 Alpha-2B adrenergic receptor ADRA2B 0.1022
378 Alpha-2C adrenergic receptor ADRA2C 0.0986
492 Histamine H1 receptor HRH1 0.0969
3941 Amine oxidase [flavin-containing] A MAOA 0.0918
4924 Cytochrome P450 2C8 CYP2C8 0.0903
831 D(2) dopamine receptor DRD2 0.0902
6107 Cytochrome P450 3A7 CYP3A7 0.0769
23 D(1A) dopamine receptor DRD1 0.0768
3939 Amine oxidase [flavin-containing] B MAOB 0.0725
789 Alpha-1D adrenergic receptor ADRA1D 0.0692
6013 Cytochrome P450 2E1 CYP2E1 0.0691
590 5-hydroxytryptamine 2C receptor HTR2C 0.0659
320 5-hydroxytryptamine 1A receptor HTR1A 0.0601
766 Beta-2 adrenergic receptor ADRB2 0.0549
5718 Cytochrome P450 2A6 CYP2A6 0.0534
193 Beta-1 adrenergic receptor ADRB1 0.0493
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0469
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0454
3923 Cholinesterase BCHE 0.0434
6024 Cytochrome P450 1A1 CYP1A1 0.043
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0423
6147 Solute carrier family 22 member 3 SLC22A3 0.0409
4079 Lipoic acid synthetase, mitochondrial LIAS 0.0397
45 Lipoyltransferase 1, mitochondrial LIPT1 0.0397
6144 Solute carrier family 22 member 2 SLC22A2 0.0395
6145 Solute carrier family 22 member 1 SLC22A1 0.0393
436 5-hydroxytryptamine 2B receptor HTR2B 0.0384
105 Sodium-dependent multivitamin transporter SLC5A6 0.038
118 Organic cation/carnitine transporter 2 SLC22A5 0.0356
587 Serum albumin ALB 0.0355
638 D(3) dopamine receptor DRD3 0.0352
725 5-hydroxytryptamine 1D receptor HTR1D 0.035
163 D(1B) dopamine receptor DRD5 0.0349
432 D(4) dopamine receptor DRD4 0.0344
685 Oxygen-insensitive NADPH nitroreductase nfsA 0.0327
6945 Oxygen-insensitive NADPH nitroreductase rdxA 0.0327
176 30S ribosomal protein S10 rpsJ 0.0325
6175 30S ribosomal protein S10 rpsJ 0.0325
4117 Probable pyruvate-flavodoxin oxidoreductase ydbK 0.0324
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.032
885 5-hydroxytryptamine 1B receptor HTR1B 0.0319
982 Cocaine- and amphetamine-regulated transcript protein CARTPT 0.0299
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0292
341 5-hydroxytryptamine 3 receptor HTR3A 0.0285
776 Bile salt export pump ABCB11 0.0278
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0277
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0276
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0271
716 5-hydroxytryptamine 7 receptor HTR7 0.0268
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0266
847 Mu-type opioid receptor OPRM1 0.026
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0259
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0241
146 Androgen receptor AR 0.0225
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0225
862 Multidrug resistance-associated protein 1 ABCC1 0.0221
1517 Beta-3 adrenergic receptor ADRB3 0.0221
3811 Cytochrome P450 19A1 CYP19A1 0.0215
6106 Cytochrome P450 2C18 CYP2C18 0.0215
20 Prostaglandin G/H synthase 1 PTGS1 0.0202
474 Acetylcholinesterase ACHE 0.0196
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0195
1898 Cytochrome P450 1B1 CYP1B1 0.0186
465 Calmodulin CALM1 0.0168
871 Glucocorticoid receptor NR3C1 0.0168
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0167
1656 CYP2B protein CYP2B 0.0166
3947 Xanthine dehydrogenase/oxidase XDH 0.0158
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0157
1256 5-hydroxytryptamine 6 receptor HTR6 0.0153
136 Estrogen receptor ESR1 0.015
6137 Multidrug resistance-associated protein 6 ABCC6 0.0141
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.014
731 HIV-1 protease HIV-1 protease 0.0138
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.013
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.013
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.013
817 DNA topoisomerase 2-alpha TOP2A 0.0126
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0125
6148 Multidrug resistance-associated protein 7 ABCC10 0.0123
696 Kappa-type opioid receptor OPRK1 0.0121
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0118
124 Histamine H2 receptor HRH2 0.0116
6020 Aldehyde oxidase AOX1 0.0115
260 Cytochrome P450 51 ERG11 0.0114
761 Cytochrome P450 51 ERG11 0.0114
3163 Cytochrome P450 51 cyp51 0.0114
467 Delta-type opioid receptor OPRD1 0.0113
3810 Catechol O-methyltransferase COMT 0.0108
828 Phenylalanine-4-hydroxylase PAH 0.0107
3109 Phenylalanine-4-hydroxylase phhA 0.0107
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0107
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.01
468 Cytochrome P450 4A11 CYP4A11 0.0099
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0098
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0097
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0097
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0096
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0096
122 P2Y purinoceptor 12 P2RY12 0.0095
528 5-hydroxytryptamine 1E receptor HTR1E 0.0094
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0094
818 50S ribosomal protein L10 rplJ 0.009
1729 Solute carrier family 22 member 6 SLC22A6 0.009
76 Nitric-oxide synthase, brain NOS1 0.009
3426 Glutamine synthetase glnA 0.009
3987 Glutamine synthetase GLUL 0.009
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0087
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0087
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0085
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0084
1757 Myeloperoxidase MPO 0.0084
833 Organic cation/carnitine transporter 1 SLC22A4 0.0082
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0082
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0082
232 Corticosteroid-binding globulin SERPINA6 0.008
6068 Guanylate cyclase soluble subunit alpha-2 GUCY1A2 0.0079
4192 DNA topoisomerase 2-beta TOP2B 0.0078
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0078
290 Prostaglandin G/H synthase 2 PTGS2 0.0078
6138 Multidrug resistance protein 3 ABCB4 0.0077
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0076
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0076
6142 Solute carrier family 22 member 8 SLC22A8 0.0076
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0076
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0075
6070 Nischarin NISCH 0.0075
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0075
174 Sigma 1-type opioid receptor SIGMAR1 0.0074
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.0073
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0073
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0072
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.0072
3876 Aromatic-L-amino-acid decarboxylase DDC 0.0071
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0071
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.007
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0069
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0069
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0068
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.0068
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0066
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0066
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0066
705 Glutamate receptor 1 GRIA1 0.0064
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0064
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0064
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0064
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0063
482 Glycine receptor subunit alpha-1 GLRA1 0.0063
614 Progesterone receptor PGR 0.0062
6168 Solute carrier family 22 member 16 SLC22A16 0.0062
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0061
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0061
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0061
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0061
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.006
2164 Multidrug resistance-associated protein 4 ABCC4 0.006
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.006
4148 Serine/threonine-protein kinase mTOR MTOR 0.0059
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.0059
6031 Cytochrome P450 3A43 CYP3A43 0.0059
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.0057
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0057
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0057
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.0057
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.0057
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0057
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0057
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0056
241 Calcium-transporting ATPase type 2C member 1 ATP2C1 0.0056
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0055
6220 Aryl hydrocarbon receptor AHR 0.0055
29 Tubulin beta-1 chain TUBB1 0.0055
606 Cytochrome P450 27, mitochondrial CYP27A1 0.0054
811 Translocator protein TSPO 0.0053
537 ATP synthase delta chain, mitochondrial ATP5D 0.0053
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0053
756 Sex hormone-binding globulin SHBG 0.0052
7 Nitric oxide synthase, inducible NOS2 0.0052
504 Mast/stem cell growth factor receptor KIT 0.0051
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0051
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0051
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.005
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.005
4604 Liver carboxylesterase 1 CES1 0.005
80 Peroxisome proliferator-activated receptor alpha PPARA 0.005
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.005
233 Potassium channel subfamily K member 2 KCNK2 0.005
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.005
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.0049
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.0049
6182 Cytochrome P450 2J2 CYP2J2 0.0049
161 Tubulin beta chain TUBB 0.0048
312 Tubulin beta chain TUB2 0.0048
6143 Solute carrier family 22 member 7 SLC22A7 0.0048
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0047
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0047
5073 Ferredoxin--NADP reductase petH 0.0046
5076 Ferredoxin--NADP reductase fpr 0.0046
5119 Ferredoxin--NADP reductase petH 0.0046
5121 Ferredoxin--NADP reductase fpr 0.0046
856 Vitamin D3 receptor VDR 0.0046
869 Estrogen receptor beta ESR2 0.0046
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0045
952 Dipeptidyl peptidase 4 DPP4 0.0045
215 Sodium channel protein type 11 subunit alpha SCN11A 0.0045
291 Nitric-oxide synthase, endothelial NOS3 0.0044
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0044
654 Flavin reductase BLVRB 0.0043
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0043
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0043
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0042
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0042
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0042
3997 Cytochrome P450 24A1, mitochondrial CYP24A1 0.0041
6136 Multidrug resistance-associated protein 5 ABCC5 0.004
1010 Cytochrome P450 51A1 CYP51A1 0.0039
276 Sodium- and chloride-dependent GABA transporter 1 SLC6A1 0.0039
1618 High affinity nerve growth factor receptor NTRK1 0.0039
1129 C-C chemokine receptor type 5 CCR5 0.0039
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0039
3932 Glutathione S-transferase A2 GSTA2 0.0039
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0038
5878 Alpha-7 nicotinic cholinergic receptor subunit CHRFAM7A 0.0038
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0038
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.0038
891 Dihydropteroate synthase folP 0.0038
5359 Dihydropteroate synthase folP 0.0038
7175 Dihydropteroate synthase sulI 0.0038
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0038
6432 Transporter snf 0.0037
407 Vascular endothelial growth factor receptor 2 KDR 0.0037
427 Substance-P receptor TACR1 0.0036
68 Cannabinoid receptor 1 CNR1 0.0036
4503 NADPH-flavin oxidoreductase frp 0.0035
5189 Trimethylamine dehydrogenase tmd 0.0035
4836 Ferredoxin-dependent glutamate synthase 2 gltS 0.0035
284 DNA-directed RNA polymerase beta chain rpoB 0.0035
5773 DNA-directed RNA polymerase beta chain rpoB 0.0035
4237 50S ribosomal protein L22 rplV 0.0035
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0035
185 Vasopressin V1a receptor AVPR1A 0.0035
6859 Protein S100-A4 S100A4 0.0035
939 50S ribosomal protein L3 rplC 0.0035
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0034
322 Vasopressin V2 receptor AVPR2 0.0034
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0034
5201 FMN-binding protein DvMF_2023 0.0034
5178 Protein nrdI nrdI 0.0034
3293 Flavodoxin Not Available 0.0034
4614 Flavodoxin DVU_2680 0.0034
5172 Flavodoxin isiB 0.0034
5173 Flavodoxin isiB 0.0034
5182 Flavodoxin fldA 0.0034
5198 Flavodoxin-1 fldA 0.0034
5170 Epidermin decarboxylase epiD 0.0034
5179 Probable aromatic acid decarboxylase pad1 0.0034
5175 Hypothetical protein SMU.260 SMU_260 0.0034
5202 Nitroreductase family protein BC_1844 0.0034
5197 Trp repressor binding protein WrbA, putative DR_A0214 0.0034
2586 Isopentenyl-diphosphate Delta-isomerase idi 0.0034
5187 Isopentenyl-diphosphate delta-isomerase fni 0.0034
5199 Isopentenyl-diphosphate delta-isomerase fni 0.0034
5131 PhzG phzG 0.0034
5181 Hypothetical protein yhdA azr 0.0034
153 Dopamine beta-hydroxylase DBH 0.0034
5190 Rubredoxin-oxygen oxidoreductase roo 0.0034
5200 NADH dehydrogenase nox 0.0034
5191 Morphinone reductase morB 0.0034
5193 Phenazine biosynthesis protein phzG phzG 0.0034
4405 Nitric oxide reductase fprA 0.0034
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0034
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0034
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0034
6014 Cytochrome P450 2A13 CYP2A13 0.0034
26 Vascular endothelial growth factor receptor 3 FLT4 0.0033
844 Epidermal growth factor receptor EGFR 0.0033
444 Alcohol dehydrogenase 1B ADH1B 0.0033
596 3-oxo-5-alpha-steroid 4-dehydrogenase 1 SRD5A1 0.0033
6100 BDNF/NT-3 growth factors receptor NTRK2 0.0033
295 Carbonic anhydrase 1 CA1 0.0033
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0033
814 Ryanodine receptor 1 RYR1 0.0033
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0032
32 Vascular endothelial growth factor receptor 1 FLT1 0.0032
592 Carbonic anhydrase 4 CA4 0.0032
921 Glutamate receptor 2 GRIA2 0.0032
140 30S ribosomal protein S9 rpsI 0.0031
6719 30S ribosomal protein S9 rpsI 0.0031
6725 30S ribosomal protein S9 rpsI 0.0031
3772 3-oxoacyl-[acyl-carrier-protein] reductase fabG 0.0031
5326 Oxidoreductase, short chain dehydrogenase/reductase family TM_0441 0.0031
5157 Dehydrogenase/reductase SDR family member 11 DHRS11 0.0031
5346 Oxidoreductase, aldo/keto reductase family TM_1009 0.0031
5332 MtdA bifunctional protein mtdA 0.0031
5322 Oxidoreductase ydhF ydhF 0.0031
4403 Protein iolS iolS 0.0031
5343 NADP-dependent fatty aldehyde dehydrogenase aldH 0.0031
5330 General stress protein 69 yhdN 0.0031
5333 Alcohol dehydrogenase, iron-containing TM_0920 0.0031
5342 NADH-dependent butanol dehydrogenase, putative TM_0820 0.0031
3778 NAD(P) transhydrogenase subunit beta pntB 0.0031
2578 Tubulin beta-3 chain TUBB3 0.003
408 Riboflavin kinase RFK 0.003
2285 Streptogramin A acetyltransferase vatD 0.003
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.003
228 Beta platelet-derived growth factor receptor PDGFRB 0.003
4407 FMN-dependent NADH-azoreductase azoR 0.003
5169 FMN-dependent NADH-azoreductase azoR 0.003
5176 YtnJ moxC 0.003
6043 Putative G-protein coupled receptor 44 GPR44 0.003
581 Cytochrome P450 2R1 CYP2R1 0.003
3680 Dihydroorotate dehydrogenase A pyrDA 0.003
605 Fumarate reductase flavoprotein subunit frdA 0.0029
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0029
3673 Fumarate reductase flavoprotein subunit fccA 0.0029
4912 Fumarate reductase flavoprotein subunit ifcA 0.0029
6549 Fumarate reductase flavoprotein subunit frdA 0.0029
5206 Phosphopantothenoylcysteine decarboxylase PPCDC 0.0029
3766 Pyridoxamine 5'-phosphate oxidase pdxH 0.0029
3507 Chorismate synthase aroC 0.0029
5171 Chorismate synthase aroC 0.0029
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0029
2268 Cholesterol oxidase choB 0.0029
2822 Cholesterol oxidase choA 0.0029
1024 Solute carrier family 22 member 11 SLC22A11 0.0028
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0028
6151 Monocarboxylate transporter 10 SLC16A10 0.0028
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0028
102 DNA topoisomerase I, mitochondrial TOP1MT 0.0028
723 Cytosolic phospholipase A2 PLA2G4A 0.0027
6608 Serine/threonine-protein kinase Sgk1 SGK1 0.0027
646 Malate dehydrogenase, cytoplasmic MDH1 0.0027
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0027
4582 Putative pteridine reductase 2 ptr2 0.0027
2775 Dihydroorotate dehydrogenase pyrD 0.0027
4173 Tyrosine-protein kinase JAK2 JAK2 0.0027
2375 ADP-L-glycero-D-manno-heptose-6-epimerase hldD 0.0027
2305 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 0.0027
2286 Isocitrate dehydrogenase [NADP] icd 0.0027
2302 Isocitrate dehydrogenase [NADP] icd 0.0027
2771 Isocitrate dehydrogenase [NADP] icd 0.0027
5328 Prostaglandin F synthase Tb11.02.2310 0.0027
365 Dihydrofolate reductase DHFR 0.0027
2381 Dihydrofolate reductase DFR1 0.0027
2833 Dihydrofolate reductase Not Available 0.0027
2931 Dihydrofolate reductase folA 0.0027
3544 Dihydrofolate reductase folA 0.0027
3682 Dihydrofolate reductase folA 0.0027
6642 Dihydrofolate reductase folA 0.0027
6756 Dihydrofolate reductase dfrA 0.0027
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.0027
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.0027
3446 NADP-dependent alcohol dehydrogenase adh 0.0027
2636 Shikimate dehydrogenase aroE 0.0027
3515 Shikimate dehydrogenase aroE 0.0027
729 GDP-L-fucose synthetase TSTA3 0.0027
3463 GDP-L-fucose synthetase fcl 0.0027
4628 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase gapN 0.0027
989 L-xylulose reductase DCXR 0.0027
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0027
2261 Major NAD(P)H-flavin oxidoreductase Not Available 0.0027
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0026
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.0026
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0026
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.0026
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0026
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.0026
666 NADP-dependent malic enzyme ME1 0.0026
5180 L(+)-mandelate dehydrogenase mdlB 0.0026
49 Endothelin B receptor EDNRB 0.0026
4531 Putative ketoacyl reductase actIII 0.0025
6297 Prostaglandin reductase 1 PTGR1 0.0025
6862 Aldo-keto reductase family 1 member B10 AKR1B10 0.0025
2159 Quinone oxidoreductase CRYZ 0.0025
203 Pyridoxine-5'-phosphate oxidase PNPO 0.0025
563 Thyroid peroxidase TPO 0.0025
768 FK506-binding protein 1A FKBP1A 0.0025
3062 Aspartate-semialdehyde dehydrogenase asd 0.0025
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0025
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0024
6268 Hydroxyacid oxidase 1 HAO1 0.0024
578 Endothelin-1 receptor EDNRA 0.0024
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.0024
11 NAD(P) transhydrogenase, mitochondrial NNT 0.0024
544 Potassium voltage-gated channel subfamily E member 1 KCNE1 0.0024
357 Carbonic anhydrase 2 CA2 0.0024
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0024
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0024
1483 Membrane copper amine oxidase AOC3 0.0024
6039 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A PDE11A 0.0024
5852 Type-2 angiotensin II receptor AGTR2 0.0024
1124 Sepiapterin reductase SPR 0.0024
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0023
373 Transthyretin TTR 0.0023
2675 Pteridine reductase 1 PTR1 0.0023
642 3-oxo-5-alpha-steroid 4-dehydrogenase 2 SRD5A2 0.0023
164 Histamine H4 receptor HRH4 0.0023
4486 Phenol 2-hydroxylase component B pheA2 0.0023
4477 Dihydrolipoyl dehydrogenase lpdV 0.0023
5077 Dihydrolipoyl dehydrogenase Not Available 0.0023
5117 Dihydrolipoyl dehydrogenase lpd 0.0023
4439 Ferredoxin reductase bphA4 0.0023
4284 Pentaerythritol tetranitrate reductase onr 0.0023
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0023
183 Vascular endothelial growth factor A VEGFA 0.0023
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0023
3102 Flavohemoprotein hmp 0.0023
4969 Flavohemoprotein hmp 0.0023
1353 DNA topoisomerase 1 TOP1 0.0023
3552 DNA topoisomerase 1 topA 0.0023
1374 Natriuretic peptides B NPPB 0.0023
1827 Gap junction alpha-1 protein GJA1 0.0023
1908 Vascular cell adhesion protein 1 VCAM1 0.0023
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0023
777 Tumor necrosis factor TNF 0.0023
1360 Sphingomyelin phosphodiesterase SMPD1 0.0023
70 Type-1 angiotensin II receptor AGTR1 0.0023
1262 Corticotropin-lipotropin POMC 0.0023
5078 Amine oxidase, flavin-containing PSPTO1126 0.0022
5122 Mersacidin decarboxylase mrsD 0.0022
5114 Putative acyl-CoA dehydrogenase TT_C0779 0.0022
5112 Benzoate 1,2-dioxygenase electron transfer component benC 0.0022
3763 5,10-methylenetetrahydrofolate reductase metF 0.0022
3918 5,10-methylenetetrahydrofolate reductase MTHFR 0.0022
5094 5,10-methylenetetrahydrofolate reductase metF 0.0022
5083 Cryptochrome DASH cry 0.0022
5100 Gamma-aminobutyrate metabolism dehydratase/isomerase abfD 0.0022
526 Thioredoxin reductase trxB 0.0022
3767 Thioredoxin reductase trxB 0.0022
5115 FkbI fkbI 0.0022
3133 UDP-galactopyranose mutase glf 0.0022
5099 UDP-galactopyranose mutase glf 0.0022
1329 Apoptosis-inducing factor 1, mitochondrial AIFM1 0.0022
5095 Putidaredoxin reductase camA 0.0022
5097 PROBABLE DIHYDROLIPOAMIDE DEHYDROGENASE LPDA lpdA 0.0022
5102 4-cresol dehydrogenase [hydroxylating] flavoprotein subunit pchF 0.0022
5107 Alkyl hydroperoxide reductase subunit F ahpF 0.0022
5118 Alkyl hydroperoxide reductase subunit F ahpF 0.0022
1410 Oxidoreductase HSD17B6 0.0022
4725 Oxidoreductase Not Available 0.0022
5124 Oxidoreductase Not Available 0.0022
5081 L-aspartate oxidase nadB 0.0022
5111 Phenylacetone monooxygenase pamO 0.0022
5109 Outer membrane protein p64k or PM-6 m-6 0.0022
84 Nuclear receptor 0B1 NR0B1 0.0022
737 Mineralocorticoid receptor NR3C2 0.0022
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0022
990 Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 0.0022
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0022
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0022
259 Microsomal triglyceride transfer protein large subunit MTTP 0.0022
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0022
2449 Tubulin alpha-3 chain TUBA1A 0.0021
298 Renin REN 0.0021
6506 Stathmin-4 STMN4 0.0021
275 Arachidonate 5-lipoxygenase ALOX5 0.0021
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0021
380 Cytochrome P450 17A1 CYP17A1 0.0021
741 Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 0.0021
2539 Tubulin alpha-1 chain TUBA4A 0.0021
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0021
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0021
94 5-hydroxytryptamine 4 receptor HTR4 0.002
780 Retinoic acid receptor RXR-gamma RXRG 0.002
4440 NADH peroxidase npr 0.002
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.002
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.002
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.002
6085 Fatty acid-binding protein, intestinal FABP2 0.002
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.002
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.002
750 Voltage-dependent calcium channel gamma-1 subunit CACNG1 0.002
327 Glutathione reductase gor 0.002
5110 Glutathione reductase GR2 0.002
4199 Sphingosine 1-phosphate receptor Edg-8 S1PR5 0.002
5072 N,N-dimethylglycine oxidase dmg 0.002
5091 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.002
5093 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.002
3594 Deoxyribodipyrimidine photo-lyase phr 0.002
5079 Deoxyribodipyrimidine photo-lyase phrB 0.002
5080 Deoxyribodipyrimidine photo-lyase phr 0.002
2470 Pyruvate oxidase pox5 0.0019
2526 NADPH-ferredoxin reductase fprA fprA 0.0019
440 Isovaleryl-CoA dehydrogenase, mitochondrial IVD 0.0019
6639 Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 0.0019
3506 Glutaryl-CoA dehydrogenase, mitochondrial GCDH 0.0019
667 Acyl-CoA dehydrogenase family member 8, mitochondrial ACAD8 0.0019
5003 Acyl-CoA dehydrogenase, short-chain specific Not Available 0.0019
633 Penicillin-binding proteins 1A/1B pbpA 0.0019
3247 2-oxopropyl-CoM reductase, carboxylating xecC 0.0019
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0019
2499 Tubulin beta-2C chain TUBB2C 0.0019
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0019
6141 Sodium/bile acid cotransporter SLC10A1 0.0019
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.0019
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0019
88 Retinoic acid receptor RXR-beta RXRB 0.0019
5787 Angiopoietin-1 receptor TEK 0.0019
477 DNA topoisomerase 4 subunit A parC 0.0019
886 DNA topoisomerase 4 subunit A parC 0.0019
6226 DNA topoisomerase 4 subunit A parC 0.0019
1992 Vitamin D-binding protein GC 0.0019
404 DNA gyrase subunit A gyrA 0.0018
6224 DNA gyrase subunit A gyrA 0.0018
126 D-lactate dehydrogenase dld 0.0018
3545 D-lactate dehydrogenase Not Available 0.0018
4510 D-lactate dehydrogenase ldhA 0.0018
6102 Arylamine N-acetyltransferase 2 NAT2 0.0018
5998 Toll-like receptor 8 TLR8 0.0018
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0018
319 Opioid receptor, sigma 1 OPRS1 0.0018
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0018
4238 50S ribosomal protein L4 rplD 0.0018
5578 50S ribosomal protein L4 rplD 0.0018
6173 50S ribosomal protein L4 rplD 0.0018
6219 50S ribosomal protein L4 rplD 0.0018
3254 Bifunctional protein putA [Includes: Proline dehydrogenase putA 0.0018
712 Tubulin alpha chain TUB1 0.0018
1968 ATP-sensitive inward rectifier potassium channel 12 KCNJ12 0.0018
565 Extracellular calcium-sensing receptor CASR 0.0018
3185 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM 0.0018
2893 Glycine oxidase thiO 0.0018
683 Potassium transporter GK0582 0.0018
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0018
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0018
904 Glutathione S-transferase P GSTP1 0.0017
67 Prolyl 4-hydroxylase subunit alpha-1 P4HA1 0.0017
613 Atrial natriuretic peptide receptor A NPR1 0.0017
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0017
621 Periplasmic [Fe] hydrogenase 1 Not Available 0.0017
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0017
543 Penicillin-binding protein 1B mrcB 0.0017
6186 Penicillin-binding protein 1B ponB 0.0017
6822 Penicillin-binding protein 1b pbp1b 0.0017
6844 Penicillin-binding protein 1b pbp1b 0.0017
2567 Thymidylate synthase thyX thyX 0.0017
1630 Integrin beta-2 ITGB2 0.0017
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0017
2823 Trypanothione reductase TPR 0.0017
1050 Bile salt sulfotransferase SULT2A1 0.0017
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0017
159 Penicillin-binding protein 2B penA 0.0017
6121 Penicillin-binding protein 2B penA 0.0017
165 FL cytokine receptor FLT3 0.0017
2769 P-hydroxybenzoate hydroxylase pobA 0.0017
2809 P-hydroxybenzoate hydroxylase pobA 0.0017
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0017
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0016
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0016
822 Aldose reductase AKR1B1 0.0016
1852 Microtubule-associated protein 2 MAP2 0.0016
173 Toll-like receptor 7 TLR7 0.0016
2380 Monomeric sarcosine oxidase soxA 0.0016
3233 Bile acid receptor NR1H4 0.0015
251 Alcohol dehydrogenase 1A ADH1A 0.0015
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.0015
6645 D-amino-acid oxidase DAO 0.0015
1629 Transcription factor AP-1 JUN 0.0015
3937 Fatty-acid amide hydrolase FAAH 0.0015
719 Retinoic acid receptor responder protein 1 RARRES1 0.0014
770 Retinoic acid-induced protein 3 GPRC5A 0.0014
1541 Metalloproteinase mmp20 0.0014
820 Glycine receptor subunit alpha-2 GLRA2 0.0014
6032 PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) fas 0.0014
469 Annexin A1 ANXA1 0.0014
896 Glutathione S-transferase Mu 1 GSTM1 0.0014
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0014
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0014
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0014
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0014
936 Ephrin type-A receptor 2 EPHA2 0.0013
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0013
714 Glutathione reductase, mitochondrial GSR 0.0013
3809 Estrogen-related receptor gamma ESRRG 0.0013
5798 Mitogen-activated protein kinase 11 MAPK11 0.0013
4122 Histone deacetylase 2 HDAC2 0.0013
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.0013
1192 Sulfotransferase 1A1 SULT1A1 0.0013
569 Retinal dehydrogenase 2 ALDH1A2 0.0013
267 Plasminogen activator inhibitor 1 SERPINE1 0.0013
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0013
6116 Gastric triacylglycerol lipase LIPF 0.0012
823 Fibroblast growth factor receptor 2 FGFR2 0.0012
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.0012
16 Adenosine A1 receptor ADORA1 0.0012
3806 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A 0.0012
738 Monocarboxylate transporter 1 SLC16A1 0.0012
3823 Cytokine receptor common gamma chain IL2RG 0.0012
85 Growth hormone receptor GHR 0.0012
6126 Carbonic anhydrase 7 CA7 0.0012
2107 Microtubule-associated protein 1A MAP1A 0.0012
571 Melatonin receptor type 1A MTNR1A 0.0012
362 Melatonin receptor type 1B MTNR1B 0.0012
338 DNA polymerase UL30 0.0012
379 DNA polymerase UL54 0.0012
697 DNA polymerase ORF28 0.0012
2482 DNA polymerase 43 0.0012
4104 DNA polymerase BALF5 0.0012
611 Retinal dehydrogenase 1 ALDH1A1 0.0012
517 Alcohol dehydrogenase 1C ADH1C 0.0012
1768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit GNG2 0.0012
1295 Fatty acid synthase FASN 0.0012
1571 G protein-activated inward rectifier potassium channel 1 KCNJ3 0.0012
1268 Neuropeptide S receptor NPSR1 0.0012
1581 G protein-activated inward rectifier potassium channel 2 KCNJ6 0.0012
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0012
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0012
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0012
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0012
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0012
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0012
6221 Steroid hormone receptor ERR1 ESRRA 0.0012
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0012
1178 Adenosine A2a receptor ADORA2A 0.0011
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0011
239 Coagulation factor X F10 0.0011
5934 Cytochrome P450 26A1 CYP26A1 0.0011
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0011
754 Pancreatic triacylglycerol lipase PNLIP 0.0011
751 Potassium channel subfamily K member 6 KCNK6 0.0011
1039 Histone deacetylase 9 HDAC9 0.0011
6146 High affinity copper uptake protein 1 SLC31A1 0.0011
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0011
6073 Potassium channel subfamily K member 9 KCNK9 0.0011
6072 Potassium channel subfamily K member 3 KCNK3 0.0011
2178 Metabotropic glutamate receptor 5 GRM5 0.0011
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0011
724 Interleukin-2 receptor alpha chain IL2RA 0.0011
717 Interleukin-2 receptor subunit beta IL2RB 0.0011
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.001
54 Prothrombin F2 0.001
1810 Protein S100-A1 S100A1 0.001
6097 Protein S100-A2 S100A2 0.001
4203 Histamine N-methyltransferase HNMT 0.001
4116 Dihydropteroate synthetase Not Available 0.001
4228 Keratin, type II cytoskeletal 7 KRT7 0.001
172 Potassium channel subfamily K member 1 KCNK1 0.001
1144 Hepatocyte growth factor receptor MET 0.001
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.001
493 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 0.001
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.001
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.001
512 DNA-directed RNA polymerase alpha chain rpoA 0.001
5772 DNA-directed RNA polymerase alpha chain rpoA 0.001
5300 Antigen peptide transporter 1 TAP1 0.001
4041 Microsomal glutathione S-transferase 2 MGST2 0.001
6824 Tyrosine-protein kinase Lyn LYN 0.001
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.001
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.001
908 Glutathione S-transferase theta-1 GSTT1 0.001
162 Retinoic acid receptor gamma-1 RARG 0.0009
4773 Deoxycytidine kinase DCK 0.0009
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0009
6105 3-oxo-5-beta-steroid 4-dehydrogenase AKR1D1 0.0009
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0009
3086 Plasmepsin-2 Not Available 0.0009
459 Retinoic acid receptor RXR-alpha RXRA 0.0009
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0009
1048 Protein S100-A13 S100A13 0.0009
2226 Protein S100-A12 S100A12 0.0009
1759 85 kDa calcium-independent phospholipase A2 PLA2G6 0.0009
1770 Phospholipase C PLCL1 0.0009
2841 Phospholipase C plc 0.0009
1648 Elastin ELN 0.0009
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0009
6131 Carbonic anhydrase 14 CA14 0.0009
2283 Steroid Delta-isomerase ksi 0.0009
2920 Steroid Delta-isomerase ksi 0.0009
518 Peroxidase/catalase T katG 0.0009
208 DNA-directed RNA polymerase beta' chain rpoC 0.0009
5774 DNA-directed RNA polymerase beta' chain rpoC 0.0009
390 Adenosine A3 receptor ADORA3 0.0009
6169 ATP-binding cassette sub-family A member 5 ABCA5 0.0009
2132 Protein S100-B S100B 0.0009
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0008
3404 Exotoxin A eta 0.0008
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0008
22 30S ribosomal protein S4 rpsD 0.0008
6714 30S ribosomal protein S4 rpsD 0.0008
6122 Carbonic anhydrase 3 CA3 0.0008
2325 Sulfotransferase family cytosolic 2B member 1 SULT2B1 0.0008
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0008
2207 Rhodopsin RHO 0.0008
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0008
2298 Cytochrome P450-cam camC 0.0008
1867 Major prion protein PRNP 0.0008
2232 Interleukin-5 IL5 0.0008
1593 Mucin-2 MUC2 0.0008
4031 Glutathione S-transferase A1 GSTA1 0.0008
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0008
1649 Small inducible cytokine A2 CCL2 0.0008
6163 Copper-transporting ATPase 2 ATP7B 0.0008
6165 Copper-transporting ATPase 1 ATP7A 0.0008
1025 Aquaporin-1 AQP1 0.0008
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0008
3856 Fibroblast growth factor receptor 3 FGFR3 0.0008
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0008
2091 Endoplasmin HSP90B1 0.0008
6893 Calcium/calmodulin-dependent protein kinase type II gamma chain CAMK2G 0.0007
473 L-lactate dehydrogenase A chain LDHA 0.0007
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0007
461 Glycine receptor subunit alpha-3 GLRA3 0.0007
620 Bifunctional dihydrofolate reductase-thymidylate synthase Not Available 0.0007
130 Prostacyclin synthase PTGIS 0.0007
6103 Arylamine N-acetyltransferase 1 NAT1 0.0007
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0007
2981 Phospholipase A2, membrane associated PLA2G2A 0.0007
2112 Toll-like receptor 9 TLR9 0.0007
6207 30S ribosomal protein S14 rpsN 0.0007
6209 30S ribosomal protein S19 rpsS 0.0007
6712 30S ribosomal protein S19 rpsS 0.0007
6726 30S ribosomal protein S19 rpsS 0.0007
645 Penicillin-binding protein 1A mrcA 0.0007
5805 Penicillin-binding protein 1A ponA 0.0007
6185 Penicillin-binding protein 1A mrcA 0.0007
6799 Penicillin-binding protein 1A pbpA 0.0007
5924 Microtubule-associated protein 4 MAP4 0.0007
5923 Microtubule-associated protein tau MAPT 0.0007
2290 ADP-ribosyl cyclase 2 BST1 0.0007
24 Thymidylate synthase TMP1 0.0007
359 Thymidylate synthase TYMS 0.0007
2626 Thymidylate synthase thyA 0.0007
2729 Thymidylate synthase thyA 0.0007
5352 Thymidylate synthase THYA 0.0007
226 Gonadotropin-releasing hormone receptor GNRHR 0.0007
1830 5'-nucleotidase NT5E 0.0007
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0007
125 DNA polymerase beta POLB 0.0007
4311 tRNA TRDMT1 0.0007
4325 tRNA trmD 0.0007
4328 tRNA trmD 0.0007
1123 Eosinophil cationic protein RNASE3 0.0007
2599 Tyrosine-protein kinase HCK HCK 0.0007
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0006
144 Hemoglobin subunit alpha HBA1 0.0006
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0006
106 Cannabinoid receptor 2 CNR2 0.0006
6174 50S ribosomal protein L32 rpmF 0.0006
273 Apoptosis regulator Bcl-2 BCL2 0.0006
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0006
1196 Complement decay-accelerating factor CD55 0.0006
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0006
890 Niemann-Pick C1-like protein 1 NPC1L1 0.0006
3126 Poly [ADP-ribose] polymerase 1 PARP1 0.0006
6167 Organic solute transporter subunit beta OSTB 0.0006
6166 Organic solute transporter subunit alpha OSTA 0.0006
3611 Cytidine deaminase cdd 0.0006
3707 Cytidine deaminase cdd 0.0006
4211 Cytidine deaminase CDA 0.0006
1291 cAMP response element-binding protein CREB1 0.0006
1569 G1/S-specific cyclin-D1 CCND1 0.0006
1525 Heparin-binding growth factor 2 FGF2 0.0006
634 Squalene monooxygenase SQLE 0.0006
7196 Squalene monooxygenase ERG1 0.0006
4210 Toll-like receptor 4 TLR4 0.0005
2808 Chloramphenicol acetyltransferase 3 cat3 0.0005
1341 Histamine H3 receptor HRH3 0.0005
1760 Aminopeptidase N ANPEP 0.0005
6843 Aminopeptidase N pepN 0.0005
117 Sterol O-acyltransferase 1 SOAT1 0.0005
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0005
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.0005
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.0005
244 Angiotensin-converting enzyme ACE 0.0005
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0005
6211 Tubulin epsilon chain TUBE1 0.0005
6212 Tubulin gamma-1 chain TUBG1 0.0005
6210 Tubulin delta chain TUBD1 0.0005
2417 Chloramphenicol acetyltransferase cat 0.0005
3278 Chloramphenicol acetyltransferase cat 0.0005
2810 Dr hemagglutinin structural subunit draA 0.0005
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0005
3601 Dihydropteroate synthase 1 folP1 0.0005
3807 Dihydropteroate synthase 1 folP1 0.0005
3808 Dihydropteroate synthase 2 folP2 0.0005
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.0005
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0005
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0005
1714 Mitogen-activated protein kinase 3 MAPK3 0.0005
2236 Casein kinase II subunit alpha CSNK2A1 0.0005
3913 Glutamic acid decarboxylase GAD65 0.0005
6149 Solute carrier family 22 member 10 SLC22A10 0.0005
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0004
476 RAC-alpha serine/threonine-protein kinase AKT1 0.0004
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0004
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0004
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0004
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0004
4925 Cytochrome c-type protein SHP shp 0.0004
4954 Soluble cytochrome b558 Not Available 0.0004
4916 Cyanoglobin glbN 0.0004
4994 Hemoglobin-like protein HbO glbO 0.0004
4915 Cytochrome c-550 psbV 0.0004
4959 Cytochrome c-550 psbV 0.0004
5216 Cytochrome c-550 psbV 0.0004
4943 Cytochrome c6 petJ 0.0004
4984 Neuroglobin NGB 0.0004
3116 Bacterioferritin bfr 0.0004
4906 Bacterioferritin bfr 0.0004
4965 Bacterioferritin bfr 0.0004
4947 Bacterial hemoglobin vhb 0.0004
4975 Cytochrome c-556 RPA3973 0.0004
4934 Cytochrome c-551 nirM 0.0004
5218 Cytochrome c-551 nirM 0.0004
4936 Cytochrome c2 iso-2 Not Available 0.0004
4905 Cytochrome c2 Not Available 0.0004
4939 Cytochrome c2 cycA 0.0004
4964 Cytochrome c2 cycA 0.0004
4979 Cytochrome c2 cycA 0.0004
6673 Cytochrome c2 cycA 0.0004
4910 Cytoglobin CYGB 0.0004
4981 Iron-starvation protein PigA pigA 0.0004
4909 CooA protein cooA 0.0004
4907 Cytochrome c-L moxG 0.0004
6865 Cytochrome c-L moxG 0.0004
4998 Hemoglobin-like protein yjbI yjbI 0.0004
5000 HemO hemO 0.0004
4942 Diheme cytochrome c napB napB 0.0004
4935 Cytochrome c-554 cycA1 0.0004
644 Heme oxygenase 2 HMOX2 0.0004
4982 Heme oxygenase 2 pbsA2 0.0004
4972 P450cin cinA 0.0004
4904 Cytochrome c family protein GSU1996 0.0004
4971 Nonaheme cytochrome c hmcA 0.0004
4961 Hemophore HasA hasA 0.0004
4976 Apocytochrome f petA 0.0004
6407 Apocytochrome f petA 0.0004
4931 Cytochrome P450 167A1 CYP167A1 0.0004
4960 Putative cytochrome P450-family protein SCO7417 0.0004
4764 Cytochrome P450 165C4 CYP165C4 0.0004
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0004
4903 Methyl-accepting chemotaxis protein Tar4 0.0004
4926 Heme-based aerotactic transducer hemAT hemAT 0.0004
4999 Cytochrome P450 165B3 CYP165B3 0.0004
4993 Hydroxylamine oxidoreductase hao1 0.0004
4989 Cytochrome c551 peroxidase ccp 0.0004
5222 Cytochrome c551 peroxidase ccpA 0.0004
4937 Cytochrome oxidase subunit II rcoxA 0.0004
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0004
4922 Cytochrome c, putative SO_4144 0.0004
4952 Catalase/peroxidase katA 0.0004
3093 Catalase HPII katE 0.0004
4103 Proteasome subunit beta type 2 PSMB2 0.0004
4101 Proteasome subunit beta type 1 PSMB1 0.0004
4102 Proteasome subunit beta type 5 PSMB5 0.0004
976 Platelet glycoprotein IX GP9 0.0004
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0004
935 Proto-oncogene tyrosine-protein kinase Yes YES1 0.0004
1063 Signal transducer and activator of transcription 5B STAT5B 0.0004
2216 Fibroblast growth factor receptor 4 FGFR4 0.0004
4217 Telomerase reverse transcriptase TERT 0.0004
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0004
735 Alanine aminotransferase 1 GPT 0.0004
3904 Alanine aminotransferase 2 GPT2 0.0004
511 5-hydroxytryptamine 1F receptor HTR1F 0.0004
1176 Mitogen-activated protein kinase 1 MAPK1 0.0004
594 Thyroxine-binding globulin SERPINA7 0.0004
6048 Troponin C, skeletal muscle TNNC2 0.0004
934 Proto-oncogene tyrosine-protein kinase Fyn FYN 0.0004
268 Adenosine A2b receptor ADORA2B 0.0003
6044 Serum paraoxonase/lactonase 3 PON3 0.0003
758 Thyroid hormone receptor alpha THRA 0.0003
33 Cystine/glutamate transporter SLC7A11 0.0003
484 Tyrosine-protein kinase ABL2 ABL2 0.0003
2240 Cell division protein kinase 2 CDK2 0.0003
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0003
572 Integrin alpha-L ITGAL 0.0003
199 Monocarboxylate transporter 8 SLC16A2 0.0003
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0003
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0003
2320 Thymidine kinase, cytosolic TK1 0.0003
4920 Peroxidase/catalase katG 0.0003
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0003
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0003
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0003
4948 Cytochrome c-553 Not Available 0.0003
4923 Cytochrome c3 DvMF_2499 0.0003
4945 Cytochrome c3 Not Available 0.0003
4949 Cytochrome c3 DVU_3171 0.0003
4968 Cytochrome c3 cytc3 0.0003
4997 Cytochrome c3 SO_2727 0.0003
5219 Cytochrome c3 cyd 0.0003
4902 Nine-heme cytochrome c Ddes_2038 0.0003
2119 Cytochrome b5 CYB5A 0.0003
4990 PpcA ppcA 0.0003
3189 High-molecular-weight cytochrome c hmcA 0.0003
3375 Acidic cytochrome c3 Not Available 0.0003
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0003
4988 Sulfite oxidase, mitochondrial SUOX 0.0003
2915 Sensor protein fixL fixL 0.0003
4944 Sensor protein fixL fixL 0.0003
4385 Cytochrome c' Not Available 0.0003
4967 Cytochrome c' cycA 0.0003
5038 Cytochrome c' Not Available 0.0003
5223 Cytochrome c' cycP 0.0003
4813 Heme oxygenase hmuO 0.0003
5769 Heme oxygenase Not Available 0.0003
3570 Cytochrome P450 152A1 cypC 0.0003
4037 Hypothetical protein GPX1 0.0003
4297 Hypothetical protein SP_1951 0.0003
4521 Hypothetical protein BC_2969 0.0003
4540 Hypothetical protein TM_1070 0.0003
4555 Hypothetical protein MT1739 0.0003
4569 Hypothetical protein mshD 0.0003
4578 Hypothetical protein PA3270 0.0003
4747 Hypothetical protein PA3967 0.0003
5177 Hypothetical protein TM_0096 0.0003
5194 Hypothetical protein PA1204 0.0003
5240 Hypothetical protein Rv2991 0.0003
5370 Hypothetical protein TM_1158 0.0003
5710 Hypothetical protein Tb927.5.1360 0.0003
4289 Cytochrome P450 TT_P0059 0.0003
6262 Cytochrome P450 staP 0.0003
4992 Cytochrome c peroxidase Not Available 0.0003
1864 RET proto-oncogene RET 0.0003
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0003
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0003
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0003
346 Thyroid hormone receptor beta-1 THRB 0.0003
2230 Catalase CAT 0.0003
3249 Catalase katA 0.0003
3625 Catalase katA 0.0003
4539 Catalase katA 0.0003
4941 Catalase katB 0.0003
1275 Estrogen sulfotransferase SULT1E1 0.0003
760 Fibroblast growth factor 1 FGF1 0.0003
6218 Pannexin-1 PANX1 0.0003
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0003
3411 Cytochrome P450 121 cyp121 0.0003
3670 Soluble cytochrome b562 precursor cybC 0.0003
3291 Cytochrome c-552 cycA 0.0003
4927 Cytochrome c-552 nrfA 0.0003
4938 Cytochrome c-552 cycA 0.0003
4953 Cytochrome c-552 nrfA 0.0003
5217 Cytochrome c-552 cycM 0.0003
2617 Nitric oxide synthase oxygenase nos 0.0003
2701 Nitric oxide synthase oxygenase nos 0.0003
4386 Hemoglobin-like protein HbN glbN 0.0003
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0002
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0002
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0002
3127 Nitrite reductase nirS 0.0002
3284 Nitrite reductase nirS 0.0002
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0002
3221 Cytochrome c4 cc4 0.0002
2972 6-deoxyerythronolide B hydroxylase eryF 0.0002
3957 Adenosine deaminase ADA 0.0002
6135 Sodium channel subunit beta-4 SCN4B 0.0002
6134 Sodium channel subunit beta-3 SCN3B 0.0002
6132 Sodium channel subunit beta-1 SCN1B 0.0002
6127 Carbonic anhydrase-related protein CA8 0.0002
6128 Carbonic anhydrase-related protein 10 CA10 0.0002
6133 Sodium channel subunit beta-2 SCN2B 0.0002
4608 Putative cytochrome P450 SCO1207 0.0002
4963 Putative cytochrome P450 SCO2884 0.0002
6254 Putative cytochrome P450 SCO6998 0.0002
6129 Carbonic anhydrase-related protein 11 CA11 0.0002
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0002
358 Cystathionine beta-synthase CBS 0.0002
1507 Cytochrome c CYCS 0.0002
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.0002
6130 Carbonic anhydrase 13 CA13 0.0002
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0002
693 Hemoglobin subunit beta HBB 0.0002
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0002
810 Heme oxygenase 1 HMOX1 0.0002
3391 Heme oxygenase 1 pbsA1 0.0002
489 Monocarboxylate transporter 2 SLC16A7 0.0002
3007 Carbonic anhydrase 12 CA12 0.0002
4205 Carbonic anhydrase 9 CA9 0.0002
↑