DT-Web

DB04267 - Dipicolinic Acid


Identification
Name Dipicolinic Acid
Accession Number DB04267 (EXPT02530)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 167.1189
Groups experimental
Monoisotopic Weight 167.021857653
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Dihydrodipicolinate reductase
Name Dihydrodipicolinate reductase
Gene Name dapB
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.8205
Dihydrodipicolinate reductase
Name Dihydrodipicolinate reductase
Gene Name dapB
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.8205

Predictions


Id Partner name Gene Name Score
4462 Dihydrodipicolinate reductase dapB 0.8205
4428 Redox-sensing transcriptional repressor rex rex 0.0119
4446 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase Not Available 0.0119
4449 ADP-ribosyltransferase Not Available 0.0119
4472 Glucose 1-dehydrogenase Not Available 0.0119
4448 L-2-hydroxyisocaproate dehydrogenase Not Available 0.0119
4423 Levodione reductase lvr 0.0119
4471 CDP-D-glucose-4,6-dehydratase ascB 0.0119
4505 Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase bphB 0.0119
4447 Hypothetical protein yhfP yhfP 0.0119
4443 Quinate/shikimate dehydrogenase ydiB 0.0119
4495 3-oxoacyl-(Acyl carrier protein) reductase TM_1169 0.0119
4456 Inorganic polyphosphate/ATP-NAD kinase ppnK 0.0119
4500 L-lactate dehydrogenase 2 ldh2 0.0119
4507 Alanine dehydrogenase ald 0.0119
4336 Glyceraldehyde 3-phosphate dehydrogenase Not Available 0.0119
4436 Glyceraldehyde 3-phosphate dehydrogenase tthHB8IM 0.0119
3381 Alcohol dehydrogenase Not Available 0.0119
4508 Alcohol dehydrogenase adhA 0.0119
4414 Dehydrogenase TT_P0035 0.0119
4451 Vip2Ac vip2Ac 0.0119
4418 AGR_L_3209p AGR_L_3209 0.0119
4475 Hypothetical protein Rv0046c/MT0052 ino1 0.0119
4455 Glycerol dehydrogenase gldA 0.0119
4497 Benzyl alcohol dehydrogenase xylB 0.0119
3735 NAD(P) transhydrogenase subunit alpha part 1 pntAA 0.0119
3729 Citrate synthase gltA 0.0119
4575 Citrate synthase cit 0.0119
4580 Citrate synthase gltA 0.0119
4502 Formate dehydrogenase Not Available 0.0119
2350 3-isopropylmalate dehydrogenase leuB 0.0119
3092 3-isopropylmalate dehydrogenase leuB 0.0119
4466 Glutathione-independent formaldehyde dehydrogenase fdhA 0.0119
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.0119
3726 D-3-phosphoglycerate dehydrogenase serA 0.0119
4291 D-3-phosphoglycerate dehydrogenase serA 0.0119
4435 L-aspartate dehydrogenase nadX 0.0119
4467 Alpha-glucosidase, putative TM_0752 0.0119
4506 Myo-inositol-1-phosphate synthase-related protein TM_1419 0.0119
4487 Transcriptional regulator nadR nadR 0.0119
4486 Phenol 2-hydroxylase component B pheA2 0.0104
6698 Dehydrogenase/reductase SDR family member 4-like 2 DHRS4L2 0.0103
4498 Ornithine cyclodeaminase PP3533 0.0103
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0103
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0103
2018 Deoxyhypusine synthase DHPS 0.0103
2831 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase Not Available 0.0103
3059 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase fabG3 0.0103
4509 Acetoin(diacetyl) reductase budC 0.0103
4503 NADPH-flavin oxidoreductase frp 0.0103
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0103
3598 dTDP-4-dehydrorhamnose reductase rfbD 0.0103
4482 UDP-galactose 4-epimerase galE 0.0103
2424 L-lactate dehydrogenase ldh 0.0103
2641 L-lactate dehydrogenase Not Available 0.0103
4437 L-lactate dehydrogenase ldh 0.0103
4442 L-lactate dehydrogenase ldh 0.0103
2336 2,3-diketo-L-gulonate reductase dlgD 0.0103
126 D-lactate dehydrogenase dld 0.0103
3545 D-lactate dehydrogenase Not Available 0.0103
4510 D-lactate dehydrogenase ldhA 0.0103
2967 CDP-paratose 2-epimerase rfbE 0.0103
3671 7-alpha-hydroxysteroid dehydrogenase hdhA 0.0103
3081 3-dehydroquinate synthase aroB 0.0103
3177 dTDP-glucose 4,6-dehydratase rfbB 0.0103
4499 dTDP-glucose 4,6-dehydratase rmlB 0.0103
1199 GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 ART1 0.0103
4439 Ferredoxin reductase bphA4 0.0103
3401 D-2-hydroxyisocaproate dehydrogenase Not Available 0.0103
2538 6-phospho-beta-glucosidase bglT bglT 0.0103
4496 C-terminal-binding protein 1 CTBP1 0.0103
4427 TDP-glucose-4,6-dehydratase desIV 0.0103
2881 Gamma-aminobutyraldehyde dehydrogenase prr 0.0103
2591 Urocanate hydratase hutU 0.0103
2507 Diphtheria toxin Not Available 0.0103
2393 Maltose-6'-phosphate glucosidase glvA 0.0103
4477 Dihydrolipoyl dehydrogenase lpdV 0.0103
5077 Dihydrolipoyl dehydrogenase Not Available 0.0103
5117 Dihydrolipoyl dehydrogenase lpd 0.0103
4450 Iota toxin component Ia Not Available 0.0103
3736 Glyceraldehyde-3-phosphate dehydrogenase A gapA 0.0095
2683 Mono-ADP-ribosyltransferase C3 C3 0.0095
3296 Nicotinamide mononucleotide adenylyltransferase 1 NMNAT1 0.0095
4318 Siroheme synthase cysG 0.0095
2799 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal Not Available 0.0095
3367 GDP-mannose 6-dehydrogenase algD 0.0095
4504 WbpP Not Available 0.0095
711 UDP-glucose 6-dehydrogenase UGDH 0.0095
3672 UDP-glucose 6-dehydrogenase hasB 0.0095
4343 Alpha-glucosidase aglA 0.0095
4440 NADH peroxidase npr 0.0095
816 Biliverdin reductase A BLVRA 0.0094
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0094
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0094
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0094
63 Malate dehydrogenase mdh 0.0093
2329 Malate dehydrogenase mdh 0.0093
3445 Malate dehydrogenase mdh 0.0093
4420 Malate dehydrogenase mdh 0.0093
4438 Malate dehydrogenase mdh 0.0093
4476 Mannitol dehydrogenase mtlD 0.0091
3333 Nicotinamide mononucleotide adenylyltransferase 3 NMNAT3 0.009
2434 NH(3)-dependent NAD(+) synthetase nadE 0.009
2910 NH(3)-dependent NAD(+) synthetase nadE 0.009
3217 NH(3)-dependent NAD(+) synthetase nadE 0.009
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.009
2617 Nitric oxide synthase oxygenase nos 0.009
2701 Nitric oxide synthase oxygenase nos 0.009
3070 Adenosylhomocysteinase AHCY 0.009
4424 Adenosylhomocysteinase PFE1050w 0.009
6278 Adenosylhomocysteinase ahcY 0.009
2826 Glucose--fructose oxidoreductase gfo 0.009
3191 Histidinol dehydrogenase hisD 0.009
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.009
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.009
597 Dihydropteridine reductase QDPR 0.0089
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.0089
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0089
328 Sorbitol dehydrogenase SORD 0.0089
396 Alcohol dehydrogenase 4 ADH4 0.0089
646 Malate dehydrogenase, cytoplasmic MDH1 0.0089
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0089
363 NADP-dependent malic enzyme, mitochondrial ME3 0.0089
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.0089
327 Glutathione reductase gor 0.0089
5110 Glutathione reductase GR2 0.0089
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0086
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0086
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0086
77 L-lactate dehydrogenase B chain LDHB 0.0086
12 Alcohol dehydrogenase class 3 ADH5 0.0086
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.0086
2286 Isocitrate dehydrogenase [NADP] icd 0.0083
2302 Isocitrate dehydrogenase [NADP] icd 0.0083
2771 Isocitrate dehydrogenase [NADP] icd 0.0083
4491 DNA ligase, NAD-dependent ligA 0.0083
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0083
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0083
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0083
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0083
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0083
473 L-lactate dehydrogenase A chain LDHA 0.0083
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0082
2762 UDP-glucose 4-epimerase GALE 0.008
3461 UDP-glucose 4-epimerase galE 0.008
166 NAD-dependent malic enzyme, mitochondrial ME2 0.008
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0079
569 Retinal dehydrogenase 2 ALDH1A2 0.0075
611 Retinal dehydrogenase 1 ALDH1A1 0.0075
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0074
251 Alcohol dehydrogenase 1A ADH1A 0.0074
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0072
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0071
444 Alcohol dehydrogenase 1B ADH1B 0.007
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0068
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0068
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0068
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0068
714 Glutathione reductase, mitochondrial GSR 0.0066
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0065
517 Alcohol dehydrogenase 1C ADH1C 0.0063
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