DT-Web

DB03698 - 5-Mercaptoethanol-2-Decenoyl-Coenzyme A


Identification
Name 5-Mercaptoethanol-2-Decenoyl-Coenzyme A
Accession Number DB03698 (EXPT02142)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 993.869
Groups experimental
Monoisotopic Weight 993.217958875
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


2,4-dienoyl-CoA reductase [NADPH]
Name 2,4-dienoyl-CoA reductase [NADPH]
Gene Name fadH
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.5243

Predictions


Id Partner name Gene Name Score
5073 Ferredoxin--NADP reductase petH 0.0145
5076 Ferredoxin--NADP reductase fpr 0.0145
5119 Ferredoxin--NADP reductase petH 0.0145
5121 Ferredoxin--NADP reductase fpr 0.0145
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0145
76 Nitric-oxide synthase, brain NOS1 0.0138
654 Flavin reductase BLVRB 0.0128
4120 NADPH--cytochrome P450 reductase POR 0.0121
5201 FMN-binding protein DvMF_2023 0.0106
5178 Protein nrdI nrdI 0.0106
5191 Morphinone reductase morB 0.0106
5181 Hypothetical protein yhdA azr 0.0106
5198 Flavodoxin-1 fldA 0.0106
5179 Probable aromatic acid decarboxylase pad1 0.0106
5175 Hypothetical protein SMU.260 SMU_260 0.0106
5202 Nitroreductase family protein BC_1844 0.0106
5197 Trp repressor binding protein WrbA, putative DR_A0214 0.0106
5200 NADH dehydrogenase nox 0.0106
5131 PhzG phzG 0.0106
5193 Phenazine biosynthesis protein phzG phzG 0.0106
3293 Flavodoxin Not Available 0.0106
4614 Flavodoxin DVU_2680 0.0106
5172 Flavodoxin isiB 0.0106
5173 Flavodoxin isiB 0.0106
5182 Flavodoxin fldA 0.0106
2586 Isopentenyl-diphosphate Delta-isomerase idi 0.0106
5187 Isopentenyl-diphosphate delta-isomerase fni 0.0106
5199 Isopentenyl-diphosphate delta-isomerase fni 0.0106
4037 Hypothetical protein GPX1 0.0106
4297 Hypothetical protein SP_1951 0.0106
4521 Hypothetical protein BC_2969 0.0106
4540 Hypothetical protein TM_1070 0.0106
4555 Hypothetical protein MT1739 0.0106
4569 Hypothetical protein mshD 0.0106
4578 Hypothetical protein PA3270 0.0106
4747 Hypothetical protein PA3967 0.0106
5177 Hypothetical protein TM_0096 0.0106
5194 Hypothetical protein PA1204 0.0106
5240 Hypothetical protein Rv2991 0.0106
5370 Hypothetical protein TM_1158 0.0106
5710 Hypothetical protein Tb927.5.1360 0.0106
5170 Epidermin decarboxylase epiD 0.0106
4405 Nitric oxide reductase fprA 0.0106
5190 Rubredoxin-oxygen oxidoreductase roo 0.0106
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0105
3772 3-oxoacyl-[acyl-carrier-protein] reductase fabG 0.0097
4403 Protein iolS iolS 0.0097
5322 Oxidoreductase ydhF ydhF 0.0097
5326 Oxidoreductase, short chain dehydrogenase/reductase family TM_0441 0.0097
5157 Dehydrogenase/reductase SDR family member 11 DHRS11 0.0097
5346 Oxidoreductase, aldo/keto reductase family TM_1009 0.0097
5332 MtdA bifunctional protein mtdA 0.0097
3778 NAD(P) transhydrogenase subunit beta pntB 0.0097
5330 General stress protein 69 yhdN 0.0097
5333 Alcohol dehydrogenase, iron-containing TM_0920 0.0097
5342 NADH-dependent butanol dehydrogenase, putative TM_0820 0.0097
5343 NADP-dependent fatty aldehyde dehydrogenase aldH 0.0097
4503 NADPH-flavin oxidoreductase frp 0.0092
4407 FMN-dependent NADH-azoreductase azoR 0.0092
5169 FMN-dependent NADH-azoreductase azoR 0.0092
5206 Phosphopantothenoylcysteine decarboxylase PPCDC 0.0092
3766 Pyridoxamine 5'-phosphate oxidase pdxH 0.0092
3680 Dihydroorotate dehydrogenase A pyrDA 0.0092
3507 Chorismate synthase aroC 0.0092
5171 Chorismate synthase aroC 0.0092
5176 YtnJ moxC 0.0092
5189 Trimethylamine dehydrogenase tmd 0.0092
4836 Ferredoxin-dependent glutamate synthase 2 gltS 0.0092
2775 Dihydroorotate dehydrogenase pyrD 0.0085
6608 Serine/threonine-protein kinase Sgk1 SGK1 0.0085
2636 Shikimate dehydrogenase aroE 0.0084
3515 Shikimate dehydrogenase aroE 0.0084
5328 Prostaglandin F synthase Tb11.02.2310 0.0084
4582 Putative pteridine reductase 2 ptr2 0.0084
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0084
2375 ADP-L-glycero-D-manno-heptose-6-epimerase hldD 0.0084
729 GDP-L-fucose synthetase TSTA3 0.0084
3463 GDP-L-fucose synthetase fcl 0.0084
3446 NADP-dependent alcohol dehydrogenase adh 0.0084
2305 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 0.0084
989 L-xylulose reductase DCXR 0.0084
4628 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase gapN 0.0084
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.0084
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.0084
2286 Isocitrate dehydrogenase [NADP] icd 0.0084
2302 Isocitrate dehydrogenase [NADP] icd 0.0084
2771 Isocitrate dehydrogenase [NADP] icd 0.0084
5180 L(+)-mandelate dehydrogenase mdlB 0.008
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.008
408 Riboflavin kinase RFK 0.0078
6862 Aldo-keto reductase family 1 member B10 AKR1B10 0.0078
4531 Putative ketoacyl reductase actIII 0.0078
6297 Prostaglandin reductase 1 PTGR1 0.0078
3062 Aspartate-semialdehyde dehydrogenase asd 0.0078
2261 Major NAD(P)H-flavin oxidoreductase Not Available 0.0074
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.0074
666 NADP-dependent malic enzyme ME1 0.0074
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0074
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0074
685 Oxygen-insensitive NADPH nitroreductase nfsA 0.0074
6945 Oxygen-insensitive NADPH nitroreductase rdxA 0.0074
1124 Sepiapterin reductase SPR 0.0073
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.0073
2675 Pteridine reductase 1 PTR1 0.0073
203 Pyridoxine-5'-phosphate oxidase PNPO 0.0073
4284 Pentaerythritol tetranitrate reductase onr 0.0072
646 Malate dehydrogenase, cytoplasmic MDH1 0.0072
11 NAD(P) transhydrogenase, mitochondrial NNT 0.0072
5078 Amine oxidase, flavin-containing PSPTO1126 0.007
5122 Mersacidin decarboxylase mrsD 0.007
5095 Putidaredoxin reductase camA 0.007
3763 5,10-methylenetetrahydrofolate reductase metF 0.007
3918 5,10-methylenetetrahydrofolate reductase MTHFR 0.007
5094 5,10-methylenetetrahydrofolate reductase metF 0.007
5083 Cryptochrome DASH cry 0.007
526 Thioredoxin reductase trxB 0.007
3767 Thioredoxin reductase trxB 0.007
5107 Alkyl hydroperoxide reductase subunit F ahpF 0.007
5118 Alkyl hydroperoxide reductase subunit F ahpF 0.007
5111 Phenylacetone monooxygenase pamO 0.007
5112 Benzoate 1,2-dioxygenase electron transfer component benC 0.007
5115 FkbI fkbI 0.007
3133 UDP-galactopyranose mutase glf 0.007
5099 UDP-galactopyranose mutase glf 0.007
5114 Putative acyl-CoA dehydrogenase TT_C0779 0.007
1329 Apoptosis-inducing factor 1, mitochondrial AIFM1 0.007
5100 Gamma-aminobutyrate metabolism dehydratase/isomerase abfD 0.007
5097 PROBABLE DIHYDROLIPOAMIDE DEHYDROGENASE LPDA lpdA 0.007
5102 4-cresol dehydrogenase [hydroxylating] flavoprotein subunit pchF 0.007
5081 L-aspartate oxidase nadB 0.007
1410 Oxidoreductase HSD17B6 0.007
4725 Oxidoreductase Not Available 0.007
5124 Oxidoreductase Not Available 0.007
5109 Outer membrane protein p64k or PM-6 m-6 0.007
2159 Quinone oxidoreductase CRYZ 0.0068
6268 Hydroxyacid oxidase 1 HAO1 0.0067
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0062
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0062
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0061
4486 Phenol 2-hydroxylase component B pheA2 0.0061
3506 Glutaryl-CoA dehydrogenase, mitochondrial GCDH 0.0061
3247 2-oxopropyl-CoM reductase, carboxylating xecC 0.0061
5091 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0061
5093 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0061
5003 Acyl-CoA dehydrogenase, short-chain specific Not Available 0.0061
3594 Deoxyribodipyrimidine photo-lyase phr 0.0061
5079 Deoxyribodipyrimidine photo-lyase phrB 0.0061
5080 Deoxyribodipyrimidine photo-lyase phr 0.0061
4439 Ferredoxin reductase bphA4 0.0061
667 Acyl-CoA dehydrogenase family member 8, mitochondrial ACAD8 0.0061
6639 Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 0.0061
2526 NADPH-ferredoxin reductase fprA fprA 0.0061
4477 Dihydrolipoyl dehydrogenase lpdV 0.0061
5077 Dihydrolipoyl dehydrogenase Not Available 0.0061
5117 Dihydrolipoyl dehydrogenase lpd 0.0061
440 Isovaleryl-CoA dehydrogenase, mitochondrial IVD 0.0061
2268 Cholesterol oxidase choB 0.0061
2822 Cholesterol oxidase choA 0.0061
2470 Pyruvate oxidase pox5 0.0061
5072 N,N-dimethylglycine oxidase dmg 0.0061
3102 Flavohemoprotein hmp 0.0056
4969 Flavohemoprotein hmp 0.0056
2893 Glycine oxidase thiO 0.0056
3185 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM 0.0056
4440 NADH peroxidase npr 0.0056
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0056
3254 Bifunctional protein putA [Includes: Proline dehydrogenase putA 0.0056
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0055
444 Alcohol dehydrogenase 1B ADH1B 0.0055
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0054
2567 Thymidylate synthase thyX thyX 0.0053
2823 Trypanothione reductase TPR 0.0053
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0053
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0052
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0052
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0052
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0052
2769 P-hydroxybenzoate hydroxylase pobA 0.0051
2809 P-hydroxybenzoate hydroxylase pobA 0.0051
126 D-lactate dehydrogenase dld 0.0049
3545 D-lactate dehydrogenase Not Available 0.0049
4510 D-lactate dehydrogenase ldhA 0.0049
2380 Monomeric sarcosine oxidase soxA 0.0049
327 Glutathione reductase gor 0.0049
5110 Glutathione reductase GR2 0.0049
605 Fumarate reductase flavoprotein subunit frdA 0.0048
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0048
3673 Fumarate reductase flavoprotein subunit fccA 0.0048
4912 Fumarate reductase flavoprotein subunit ifcA 0.0048
6549 Fumarate reductase flavoprotein subunit frdA 0.0048
822 Aldose reductase AKR1B1 0.0048
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0047
6645 D-amino-acid oxidase DAO 0.0046
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0046
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0046
365 Dihydrofolate reductase DHFR 0.0045
2381 Dihydrofolate reductase DFR1 0.0045
2833 Dihydrofolate reductase Not Available 0.0045
2931 Dihydrofolate reductase folA 0.0045
3544 Dihydrofolate reductase folA 0.0045
3682 Dihydrofolate reductase folA 0.0045
6642 Dihydrofolate reductase folA 0.0045
6756 Dihydrofolate reductase dfrA 0.0045
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0038
714 Glutathione reductase, mitochondrial GSR 0.0037
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0033
3939 Amine oxidase [flavin-containing] B MAOB 0.0027
3947 Xanthine dehydrogenase/oxidase XDH 0.0026
3941 Amine oxidase [flavin-containing] A MAOA 0.0024
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