DT-Web

DB02059 - Adenosine-5-Diphosphoribose


Identification
Name Adenosine-5-Diphosphoribose
Accession Number DB02059 (EXPT00544)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 559.3157
Groups experimental
Monoisotopic Weight 559.071673493
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


CDP-glucose 4,6-dehydratase
Name CDP-glucose 4,6-dehydratase
Gene Name rfbG
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.7362
Elongation factor 2
Name Elongation factor 2
Gene Name EEF2
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.2492
Glyceraldehyde-3-phosphate dehydrogenase
Name Glyceraldehyde-3-phosphate dehydrogenase
Gene Name GAPDH
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.1657
Lactaldehyde reductase
Name Lactaldehyde reductase
Gene Name fucO
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.9352
NAD-dependent deacetylase sirtuin-5
Name NAD-dependent deacetylase sirtuin-5
Gene Name SIRT5
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.1056
P-hydroxybenzoate hydroxylase
Name P-hydroxybenzoate hydroxylase
Gene Name pobA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.1102
ADP-ribose pyrophosphatase
Name ADP-ribose pyrophosphatase
Gene Name nudF
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.5442
Hypothetical protein
Name Hypothetical protein
Gene Name MT1739
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.6236
ADP compounds hydrolase nudE
Name ADP compounds hydrolase nudE
Gene Name nudE
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.8594
ADP-ribose pyrophosphatase
Name ADP-ribose pyrophosphatase
Gene Name ndx4
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.5442
NAD-dependent deacetylase sirtuin-3, mitochondrial
Name NAD-dependent deacetylase sirtuin-3, mitochondrial
Gene Name SIRT3
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available

Predictions


Id Partner name Gene Name Score
4037 Hypothetical protein GPX1 1.6236
4297 Hypothetical protein SP_1951 1.6236
4521 Hypothetical protein BC_2969 1.6236
4540 Hypothetical protein TM_1070 1.6236
4569 Hypothetical protein mshD 1.6236
4578 Hypothetical protein PA3270 1.6236
4747 Hypothetical protein PA3967 1.6236
5177 Hypothetical protein TM_0096 1.6236
5194 Hypothetical protein PA1204 1.6236
5240 Hypothetical protein Rv2991 1.6236
5370 Hypothetical protein TM_1158 1.6236
5710 Hypothetical protein Tb927.5.1360 1.6236
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 1.1657
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 1.1657
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 1.1657
2809 P-hydroxybenzoate hydroxylase pobA 1.1102
2838 Ribose-5-phosphate isomerase A rpiA 0.2844
2952 Ribose-5-phosphate isomerase A rpiA 0.2844
5595 Ribose-5-phosphate isomerase A rpiA 0.2844
5123 Protein ushA ushA 0.2358
2310 2-dehydro-3-deoxyphosphooctonate aldolase kdsA 0.2154
2542 2-dehydro-3-deoxyphosphooctonate aldolase kdsA 0.2154
3047 Ribose-phosphate pyrophosphokinase prs 0.2053
4387 Glycerol dehydratase dhaB1 0.1955
6315 V-type proton ATPase subunit B, brain isoform ATP6V1B2 0.1877
2400 Clavaminate synthase 1 cs1 0.1571
3404 Exotoxin A eta 0.1489
6 Coagulation factor XIII A chain F13A1 0.1371
2281 Haloalkane dehalogenase linB 0.1291
6792 Poly [ADP-ribose] polymerase 15 PARP15 0.1123
6791 Hypothetical exotoxin A toxA 0.1123
2741 Chorismate--pyruvate lyase ubiC 0.1024
6552 Poly [ADP-ribose] polymerase 3 PARP3 0.0901
4404 FcbC1 protein fcbC 0.0891
4165 P2Y purinoceptor 2 P2RY2 0.0522
473 L-lactate dehydrogenase A chain LDHA 0.0476
2654 Complement control protein C3L 0.0419
2290 ADP-ribosyl cyclase 2 BST1 0.0407
430 Follicle-stimulating hormone receptor FSHR 0.0378
5455 Arylsulfatase A ARSA 0.0365
3126 Poly [ADP-ribose] polymerase 1 PARP1 0.0357
814 Ryanodine receptor 1 RYR1 0.0334
2981 Phospholipase A2, membrane associated PLA2G2A 0.0295
723 Cytosolic phospholipase A2 PLA2G4A 0.026
54 Prothrombin F2 0.0206
3197 GDP-mannose mannosyl hydrolase nudD 0.017
5630 ADP-ribosylation factor-like protein 5A ARL5A 0.017
5618 ADP-ribosylation factor 4 ARF4 0.017
5628 Probable GTPase engC rsgA 0.017
1882 Ras-related C3 botulinum toxin substrate 1 RAC1 0.017
2170 Transforming protein RhoA RHOA 0.017
3366 GTP-binding protein engA der 0.017
5627 GDP-mannose 4,6-dehydratase gca 0.017
5624 GTPase rab6 0.017
6013 Cytochrome P450 2E1 CYP2E1 0.0165
3396 Elongation factor Tu tufA 0.0148
5621 Elongation factor Tu tuf 0.0148
3170 Elongation factor Tu-B tufB 0.0148
3335 Probable GTP-binding protein engB engB 0.0148
3115 Ras-related protein Rab-9 RAB9A 0.0148
3270 Elongation factor G fusA 0.0148
3354 Ras-related protein Rap-2a RAP2A 0.0148
5619 GDP-mannose 4,6 dehydratase GMDS 0.0148
3261 Signal recognition particle protein ffh 0.0148
3107 Putative GTP pyrophosphokinase relA 0.0148
4119 Cytochrome P450 2D6 CYP2D6 0.0138
6556 Elongation factor Tu GTP-binding domain-containing protein 1 EFTUD1 0.0137
6750 ADP-ribosylation factor 6 ARF6 0.0137
6447 Guanine nucleotide-binding protein G(t) subunit alpha-1 GNAT1 0.0137
2521 Cell division protein ftsZ ftsZ 0.0137
3301 Cell division protein ftsZ ftsZ 0.0137
4512 Cytochrome P450 3A4 CYP3A4 0.0124
1758 GTPase HRas HRAS 0.0123
1596 Protein-glutamine gamma-glutamyltransferase 2 TGM2 0.012
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0116
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0116
6316 ADP-ribosylation factor 1 ARF1 0.0115
2339 Protein-glutamine gamma-glutamyltransferase E TGM3 0.0114
3978 Adenylosuccinate synthetase isozyme 1 ADSSL1 0.0109
4486 Phenol 2-hydroxylase component B pheA2 0.0108
4477 Dihydrolipoyl dehydrogenase lpdV 0.0108
5077 Dihydrolipoyl dehydrogenase Not Available 0.0108
5117 Dihydrolipoyl dehydrogenase lpd 0.0108
4439 Ferredoxin reductase bphA4 0.0108
2632 Adenylosuccinate synthetase purA 0.0107
3323 Adenylosuccinate synthetase purA 0.0107
3975 Adenylosuccinate synthetase ADSS 0.0107
4598 Adenylosuccinate synthetase Adss 0.0107
6817 Adenylosuccinate synthetase purA 0.0107
4440 NADH peroxidase npr 0.0099
5626 Nucleoside diphosphate kinase B NME2 0.0096
5294 Nucleoside diphosphate kinase A NME1 0.0092
327 Glutathione reductase gor 0.0089
5110 Glutathione reductase GR2 0.0089
714 Glutathione reductase, mitochondrial GSR 0.0083
816 Biliverdin reductase A BLVRA 0.0079
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0079
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0079
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0079
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.0074
646 Malate dehydrogenase, cytoplasmic MDH1 0.0074
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.0074
597 Dihydropteridine reductase QDPR 0.0073
328 Sorbitol dehydrogenase SORD 0.0073
396 Alcohol dehydrogenase 4 ADH4 0.0073
363 NADP-dependent malic enzyme, mitochondrial ME3 0.0073
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.007
77 L-lactate dehydrogenase B chain LDHB 0.0069
12 Alcohol dehydrogenase class 3 ADH5 0.0069
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0069
4336 Glyceraldehyde 3-phosphate dehydrogenase Not Available 0.0066
4436 Glyceraldehyde 3-phosphate dehydrogenase tthHB8IM 0.0066
4472 Glucose 1-dehydrogenase Not Available 0.0066
4428 Redox-sensing transcriptional repressor rex rex 0.0066
4418 AGR_L_3209p AGR_L_3209 0.0066
4456 Inorganic polyphosphate/ATP-NAD kinase ppnK 0.0066
4414 Dehydrogenase TT_P0035 0.0066
4435 L-aspartate dehydrogenase nadX 0.0066
4505 Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase bphB 0.0066
4443 Quinate/shikimate dehydrogenase ydiB 0.0066
4423 Levodione reductase lvr 0.0066
4495 3-oxoacyl-(Acyl carrier protein) reductase TM_1169 0.0066
4500 L-lactate dehydrogenase 2 ldh2 0.0066
4447 Hypothetical protein yhfP yhfP 0.0066
4507 Alanine dehydrogenase ald 0.0066
4455 Glycerol dehydrogenase gldA 0.0066
4449 ADP-ribosyltransferase Not Available 0.0066
4506 Myo-inositol-1-phosphate synthase-related protein TM_1419 0.0066
2350 3-isopropylmalate dehydrogenase leuB 0.0066
3092 3-isopropylmalate dehydrogenase leuB 0.0066
4502 Formate dehydrogenase Not Available 0.0066
4448 L-2-hydroxyisocaproate dehydrogenase Not Available 0.0066
4497 Benzyl alcohol dehydrogenase xylB 0.0066
4487 Transcriptional regulator nadR nadR 0.0066
3735 NAD(P) transhydrogenase subunit alpha part 1 pntAA 0.0066
3729 Citrate synthase gltA 0.0066
4575 Citrate synthase cit 0.0066
4580 Citrate synthase gltA 0.0066
3381 Alcohol dehydrogenase Not Available 0.0066
4508 Alcohol dehydrogenase adhA 0.0066
4446 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase Not Available 0.0066
4451 Vip2Ac vip2Ac 0.0066
4471 CDP-D-glucose-4,6-dehydratase ascB 0.0066
4467 Alpha-glucosidase, putative TM_0752 0.0066
4475 Hypothetical protein Rv0046c/MT0052 ino1 0.0066
4466 Glutathione-independent formaldehyde dehydrogenase fdhA 0.0066
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0066
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0066
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0064
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0063
569 Retinal dehydrogenase 2 ALDH1A2 0.0059
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0059
5095 Putidaredoxin reductase camA 0.0059
5122 Mersacidin decarboxylase mrsD 0.0059
5114 Putative acyl-CoA dehydrogenase TT_C0779 0.0059
3763 5,10-methylenetetrahydrofolate reductase metF 0.0059
3918 5,10-methylenetetrahydrofolate reductase MTHFR 0.0059
5094 5,10-methylenetetrahydrofolate reductase metF 0.0059
5097 PROBABLE DIHYDROLIPOAMIDE DEHYDROGENASE LPDA lpdA 0.0059
526 Thioredoxin reductase trxB 0.0059
3767 Thioredoxin reductase trxB 0.0059
5078 Amine oxidase, flavin-containing PSPTO1126 0.0059
5112 Benzoate 1,2-dioxygenase electron transfer component benC 0.0059
5115 FkbI fkbI 0.0059
5109 Outer membrane protein p64k or PM-6 m-6 0.0059
1329 Apoptosis-inducing factor 1, mitochondrial AIFM1 0.0059
5111 Phenylacetone monooxygenase pamO 0.0059
5083 Cryptochrome DASH cry 0.0059
5100 Gamma-aminobutyrate metabolism dehydratase/isomerase abfD 0.0059
5102 4-cresol dehydrogenase [hydroxylating] flavoprotein subunit pchF 0.0059
5107 Alkyl hydroperoxide reductase subunit F ahpF 0.0059
5118 Alkyl hydroperoxide reductase subunit F ahpF 0.0059
5081 L-aspartate oxidase nadB 0.0059
1410 Oxidoreductase HSD17B6 0.0059
4725 Oxidoreductase Not Available 0.0059
5124 Oxidoreductase Not Available 0.0059
3133 UDP-galactopyranose mutase glf 0.0059
5099 UDP-galactopyranose mutase glf 0.0059
611 Retinal dehydrogenase 1 ALDH1A1 0.0059
251 Alcohol dehydrogenase 1A ADH1A 0.0058
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0057
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0057
3598 dTDP-4-dehydrorhamnose reductase rfbD 0.0057
4427 TDP-glucose-4,6-dehydratase desIV 0.0057
3177 dTDP-glucose 4,6-dehydratase rfbB 0.0057
4499 dTDP-glucose 4,6-dehydratase rmlB 0.0057
2967 CDP-paratose 2-epimerase rfbE 0.0057
4482 UDP-galactose 4-epimerase galE 0.0057
4503 NADPH-flavin oxidoreductase frp 0.0057
2507 Diphtheria toxin Not Available 0.0057
2538 6-phospho-beta-glucosidase bglT bglT 0.0057
2393 Maltose-6'-phosphate glucosidase glvA 0.0057
4509 Acetoin(diacetyl) reductase budC 0.0057
3671 7-alpha-hydroxysteroid dehydrogenase hdhA 0.0057
3081 3-dehydroquinate synthase aroB 0.0057
3615 Dihydrodipicolinate reductase dapB 0.0057
3618 Dihydrodipicolinate reductase dapB 0.0057
4462 Dihydrodipicolinate reductase dapB 0.0057
2591 Urocanate hydratase hutU 0.0057
4450 Iota toxin component Ia Not Available 0.0057
6698 Dehydrogenase/reductase SDR family member 4-like 2 DHRS4L2 0.0057
2831 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase Not Available 0.0057
3059 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase fabG3 0.0057
2424 L-lactate dehydrogenase ldh 0.0056
2641 L-lactate dehydrogenase Not Available 0.0056
4437 L-lactate dehydrogenase ldh 0.0056
4442 L-lactate dehydrogenase ldh 0.0056
3401 D-2-hydroxyisocaproate dehydrogenase Not Available 0.0056
1199 GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 ART1 0.0056
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0056
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0056
2336 2,3-diketo-L-gulonate reductase dlgD 0.0056
4496 C-terminal-binding protein 1 CTBP1 0.0056
2018 Deoxyhypusine synthase DHPS 0.0056
4498 Ornithine cyclodeaminase PP3533 0.0056
2881 Gamma-aminobutyraldehyde dehydrogenase prr 0.0056
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0056
444 Alcohol dehydrogenase 1B ADH1B 0.0055
3736 Glyceraldehyde-3-phosphate dehydrogenase A gapA 0.0053
2683 Mono-ADP-ribosyltransferase C3 C3 0.0052
4504 WbpP Not Available 0.0052
3296 Nicotinamide mononucleotide adenylyltransferase 1 NMNAT1 0.0052
3367 GDP-mannose 6-dehydrogenase algD 0.0052
2799 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal Not Available 0.0052
4318 Siroheme synthase cysG 0.0052
4343 Alpha-glucosidase aglA 0.0052
3594 Deoxyribodipyrimidine photo-lyase phr 0.0051
5079 Deoxyribodipyrimidine photo-lyase phrB 0.0051
5080 Deoxyribodipyrimidine photo-lyase phr 0.0051
2526 NADPH-ferredoxin reductase fprA fprA 0.0051
5003 Acyl-CoA dehydrogenase, short-chain specific Not Available 0.0051
667 Acyl-CoA dehydrogenase family member 8, mitochondrial ACAD8 0.0051
6639 Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 0.0051
440 Isovaleryl-CoA dehydrogenase, mitochondrial IVD 0.0051
3506 Glutaryl-CoA dehydrogenase, mitochondrial GCDH 0.0051
5073 Ferredoxin--NADP reductase petH 0.0051
5076 Ferredoxin--NADP reductase fpr 0.0051
5119 Ferredoxin--NADP reductase petH 0.0051
5121 Ferredoxin--NADP reductase fpr 0.0051
3247 2-oxopropyl-CoM reductase, carboxylating xecC 0.0051
5072 N,N-dimethylglycine oxidase dmg 0.0051
2268 Cholesterol oxidase choB 0.0051
2822 Cholesterol oxidase choA 0.0051
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0051
2470 Pyruvate oxidase pox5 0.0051
5091 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0051
5093 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0051
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.005
517 Alcohol dehydrogenase 1C ADH1C 0.005
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.005
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.005
3333 Nicotinamide mononucleotide adenylyltransferase 3 NMNAT3 0.0049
2434 NH(3)-dependent NAD(+) synthetase nadE 0.0049
2910 NH(3)-dependent NAD(+) synthetase nadE 0.0049
3217 NH(3)-dependent NAD(+) synthetase nadE 0.0049
2617 Nitric oxide synthase oxygenase nos 0.0049
2701 Nitric oxide synthase oxygenase nos 0.0049
2826 Glucose--fructose oxidoreductase gfo 0.0049
3070 Adenosylhomocysteinase AHCY 0.0049
4424 Adenosylhomocysteinase PFE1050w 0.0049
6278 Adenosylhomocysteinase ahcY 0.0049
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.0049
3191 Histidinol dehydrogenase hisD 0.0049
63 Malate dehydrogenase mdh 0.0049
2329 Malate dehydrogenase mdh 0.0049
3445 Malate dehydrogenase mdh 0.0049
4420 Malate dehydrogenase mdh 0.0049
4438 Malate dehydrogenase mdh 0.0049
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0048
4476 Mannitol dehydrogenase mtlD 0.0048
2893 Glycine oxidase thiO 0.0047
3102 Flavohemoprotein hmp 0.0047
4969 Flavohemoprotein hmp 0.0047
3185 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM 0.0047
3254 Bifunctional protein putA [Includes: Proline dehydrogenase putA 0.0047
2286 Isocitrate dehydrogenase [NADP] icd 0.0045
2302 Isocitrate dehydrogenase [NADP] icd 0.0045
2771 Isocitrate dehydrogenase [NADP] icd 0.0045
4491 DNA ligase, NAD-dependent ligA 0.0045
2567 Thymidylate synthase thyX thyX 0.0045
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0045
2823 Trypanothione reductase TPR 0.0045
2762 UDP-glucose 4-epimerase GALE 0.0044
3461 UDP-glucose 4-epimerase galE 0.0044
126 D-lactate dehydrogenase dld 0.0042
3545 D-lactate dehydrogenase Not Available 0.0042
4510 D-lactate dehydrogenase ldhA 0.0042
2380 Monomeric sarcosine oxidase soxA 0.0041
605 Fumarate reductase flavoprotein subunit frdA 0.0041
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0041
3673 Fumarate reductase flavoprotein subunit fccA 0.0041
4912 Fumarate reductase flavoprotein subunit ifcA 0.0041
6549 Fumarate reductase flavoprotein subunit frdA 0.0041
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0039
6645 D-amino-acid oxidase DAO 0.0039
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0036
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0036
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0036
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0036
3947 Xanthine dehydrogenase/oxidase XDH 0.0035
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0035
76 Nitric-oxide synthase, brain NOS1 0.003
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0028
247 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUFA1 0.0028
343 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NDUFC1 0.0028
236 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NDUFA6 0.0028
313 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NDUFB3 0.0028
607 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NDUFA2 0.0028
374 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NDUFB1 0.0028
446 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NDUFA7 0.0028
525 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NDUFA5 0.0028
417 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NDUFB6 0.0028
568 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NDUFB7 0.0028
190 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 NDUFA4 0.0028
755 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NDUFA3 0.0028
353 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 NDUFA4L2 0.0028
405 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NDUFA8 0.0028
671 Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial PDHA2 0.0028
628 Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial PDHA1 0.0028
300 NADH-ubiquinone oxidoreductase chain 4L MT-ND4L 0.0028
555 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 0.0028
746 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NDUFB8 0.0028
475 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NDUFB2 0.0028
99 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NDUFS5 0.0028
30 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NDUFV3 0.0028
219 NADH-ubiquinone oxidoreductase chain 3 MT-ND3 0.0028
41 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NDUFS8 0.0028
141 3-hydroxyisobutyrate dehydrogenase, mitochondrial HIBADH 0.0028
104 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NDUFS6 0.0028
324 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NDUFB4 0.0028
372 Estradiol 17-beta-dehydrogenase 3 HSD17B3 0.0028
598 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NDUFA11 0.0028
848 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial IDH3G 0.0028
582 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NDUFA13 0.0028
829 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NDUFA12 0.0028
609 15-hydroxyprostaglandin dehydrogenase [NAD+] HPGD 0.0028
602 Acyl carrier protein, mitochondrial NDUFAB1 0.0028
272 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NDUFB10 0.0028
384 NADH-ubiquinone oxidoreductase chain 6 MT-ND6 0.0028
152 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NDUFV2 0.0028
656 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 0.0028
729 GDP-L-fucose synthetase TSTA3 0.0028
3463 GDP-L-fucose synthetase fcl 0.0028
487 Aldo-keto reductase family 1 member C4 AKR1C4 0.0028
167 L-lactate dehydrogenase C chain LDHC 0.0028
270 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NDUFB5 0.0028
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.0028
3726 D-3-phosphoglycerate dehydrogenase serA 0.0028
4291 D-3-phosphoglycerate dehydrogenase serA 0.0028
206 3-keto-steroid reductase HSD17B7 0.0028
196 D-beta-hydroxybutyrate dehydrogenase, mitochondrial BDH1 0.0028
231 Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic GPD1 0.0028
91 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NDUFA10 0.0028
14 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial IDH3A 0.0028
335 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NDUFA9 0.0028
216 Aldehyde dehydrogenase 3B2 ALDH3B2 0.0028
616 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial IDH3B 0.0028
9 Estradiol 17-beta-dehydrogenase 2 HSD17B2 0.0028
326 L-lactate dehydrogenase A-like 6A LDHAL6A 0.0028
539 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NDUFV1 0.0028
496 Aldehyde dehydrogenase 3B1 ALDH3B1 0.0028
34 7-dehydrocholesterol reductase DHCR7 0.0028
112 L-lactate dehydrogenase A-like 6B LDHAL6B 0.0028
662 Fatty aldehyde dehydrogenase ALDH3A2 0.0028
288 Trifunctional enzyme subunit alpha, mitochondrial HADHA 0.0028
711 UDP-glucose 6-dehydrogenase UGDH 0.0028
3672 UDP-glucose 6-dehydrogenase hasB 0.0028
107 C-4 methylsterol oxidase SC4MOL 0.0028
258 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial ALDH6A1 0.0028
644 Heme oxygenase 2 HMOX2 0.0028
4982 Heme oxygenase 2 pbsA2 0.0028
637 NADH-ubiquinone oxidoreductase chain 5 MT-ND5 0.0028
721 NADH-ubiquinone oxidoreductase chain 2 MT-ND2 0.0028
531 Aldehyde dehydrogenase X, mitochondrial ALDH1B1 0.0028
50 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating NSDHL 0.0028
145 Corticosteroid 11-beta-dehydrogenase isozyme 2 HSD11B2 0.0028
643 Peroxisomal bifunctional enzyme EHHADH 0.0028
548 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NDUFS1 0.0028
393 GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase H6PD 0.0028
608 NADH-ubiquinone oxidoreductase chain 4 MT-ND4 0.0028
149 Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 0.0028
271 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial ALDH4A1 0.0028
4120 NADPH--cytochrome P450 reductase POR 0.0027
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.0025
666 NADP-dependent malic enzyme ME1 0.0025
857 Malate dehydrogenase, mitochondrial MDH2 0.0025
11 NAD(P) transhydrogenase, mitochondrial NNT 0.0024
3939 Amine oxidase [flavin-containing] B MAOB 0.0024
74 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial DLAT 0.0023
6026 Alcohol dehydrogenase 6 ADH6 0.0022
296 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial MTHFD2 0.0022
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0022
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0022
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0022
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0022
3941 Amine oxidase [flavin-containing] A MAOA 0.0021
627 11-cis retinol dehydrogenase RDH5 0.0021
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0021
640 Aldehyde dehydrogenase 1A3 ALDH1A3 0.0021
110 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.0021
248 Pyrroline-5-carboxylate reductase 1 PYCR1 0.0021
802 Pyrroline-5-carboxylate reductase 2 PYCR2 0.0021
626 Cysteine dioxygenase type 1 CDO1 0.0021
13 Aminomethyltransferase, mitochondrial AMT 0.0021
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0021
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0021
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.002
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.002
654 Flavin reductase BLVRB 0.0019
57 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I HSD3B1 0.0019
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0018
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0018
810 Heme oxygenase 1 HMOX1 0.0018
3391 Heme oxygenase 1 pbsA1 0.0018
279 Tyrosinase TYR 0.0018
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0017
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0017
380 Cytochrome P450 17A1 CYP17A1 0.0017
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0016
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0015
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0015
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0015
822 Aldose reductase AKR1B1 0.0015
365 Dihydrofolate reductase DHFR 0.0014
2381 Dihydrofolate reductase DFR1 0.0014
2833 Dihydrofolate reductase Not Available 0.0014
2931 Dihydrofolate reductase folA 0.0014
3544 Dihydrofolate reductase folA 0.0014
3682 Dihydrofolate reductase folA 0.0014
6642 Dihydrofolate reductase folA 0.0014
6756 Dihydrofolate reductase dfrA 0.0014
468 Cytochrome P450 4A11 CYP4A11 0.0014
6020 Aldehyde oxidase AOX1 0.0014
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