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Protein-glutamine gamma-glutamyltransferase 2


Partner ID 1596
Name Protein-glutamine gamma-glutamyltransferase 2
Synonyms 3371
Gene name TGM2
General function Involved in protein-glutamine gamma-glutamyltransferase activity
Specific function Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins
Gene sequence + ...

ATGGCCGAGGAGCTGGTCTTAGAGAGGTGTGATCTGGAGCTGGAGACCAATGGCCGAGACCACCACACGGCCGACCTGTGCCGGGAGAAGCTGGTGGTGCGACGGGGCCAGCCCTTCTGGCTGACCCTGCACTTTGAGGGCCGCAACTACCAGGCCAGTGTAGACAGTCTCACCTTCAGTGTCGTGACCGGCCCAGCCCCTAGCCAGGAGGCCGGGACCAAGGCCCGTTTTCCACTAAGAGATGCTGTGGAGGAGGGTGACTGGACAGCCACCGTGGTGGACCAGCAAGACTGCACCCTCTCGCTGCAGCTCACCACCCCGGCCAACGCCCCCATCGGCCTGTATCGCCTCAGCCTGGAGGCCTCCACTGGCTACCAGGGATCCAGCTTTGTGCTGGGCCACTTCATTTTGCTCTTCAACGCCTGGTGCCCAGCGGATGCTGTGTACCTGGACTCGGAAGAGGAGCGGCAGGAGTATGTCCTCACCCAGCAGGGCTTTATCTACCAGGGCTCGGCCAAGTTCATCAAGAACATACCTTGGAATTTTGGGCAGTTTCAAGATGGGATCCTAGACATCTGCCTGATCCTTCTAGATGTCAACCCCAAGTTCCTGAAGAACGCCGGCCGTGACTGCTCCCGGCGCAGCAGCCCCGTCTACGTGGGCCGGGTGGGTAGTGGCATGGTCAACTGCAACGATGACCAGGGTGTGCTGCTGGGACGCTGGGACAACAACTACGGGGACGGCGTCAGCCCCATGTCCTGGATCGGCAGCGTGGACATCCTGCGGCGCTGGAAGAACCACGGCTGCCAGCGCGTCAAGTATGGCCAGTGCTGGGTCTTCGCCGCCGTGGCCTGCACAGTGCTGAGGTGCCTAGGCATCCCTACCCGCGTCGTGACCAACTACAACTCGGCCCATGACCAGAACAGCAACCTTCTCATCGAGTACTTCCGCAATGAGTTTGGGGAGATCCAGGGTGACAAGAGCGAGATGATCTGGAACTTCCACTGCTGGGTGGAGTCGTGGATGACCAGGCCGGACCTGCAGCCGGGGTACGAGGGCTGGCAGGCCCTGGACCCAACGCCCCAGGAGAAGAGCGAAGGAACGTACTGCTGTGGCCCAGTTCCAGTTCGTGCCATCAAGGAGGGCGACCTGAGCACCAAGTACGATGCGCCCTTTGTCTTTGCGGAGGTCAATGCCGACGTGGTAGACTGGATCCAGCAGGACGATGGGTCTGTGCACAAATCCATCAACCGTTCCCTGATCGTTGGGCTGAAGATCAGCACTAAGAGCGTGGGCCGAGACGAGCGGGAGGATATCACCCACACCTACAAATACCCAGAGGGGTCCTCAGAGGAGAGGGAGGCCTTCACAAGGGCGAACCACCTGAACAAACTGGCCGAGAAGGAGGAGACAGGGATGGCCATGCGGATCCGTGTGGGCCAGAGCATGAACATGGGCAGTGACTTTGACGTCTTTGCCCACATCACCAACAACACCGCTGAGGAGTACGTCTGCCGCCTCCTGCTCTGTGCCCGCACCGTCAGCTACAATGGGATCTTGGGGCCCGAGTGTGGCACCAAGTACCTGCTCAACCTAACCCTGGAGCCTTTCTCTGAGAAGAGCGTTCCTCTTTGCATCCTCTATGAGAAATACCGTGACTGCCTTACGGAGTCCAACCTCATCAAGGTGCGGGCCCTCCTCGTGGAGCCAGTTATCAACAGCTACCTGCTGGCTGAGAGGGACCTCTACCTGGAGAATCCAGAAATCAAGATCCGGATCCTTGGGGAGCCCAAGCAGAAACGCAAGCTGGTGGCTGAGGTGTCCCTGCAGAACCCGCTCCCTGTGGCCCTGGAAGGCTGCACCTTCACTGTGGAGGGGGCCGGCCTGACTGAGGAGCAGAAGACGGTGGAGATCCCAGACCCCGTGGAGGCAGGGGAGGAAGTTAAGGTGAGAATGGACCTCGTGCCGCTCCACATGGGCCTCCACAAGCTGGTGGTGAACTTCGAGAGCGACAAGCTGAAGGCTGTGAAGGGCTTCCGGAATGTCATCATTGGCCCCGCCTAA
Protein sequence + ...

MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFSVVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLEASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPWNFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGRWDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPTPQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSLIVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIRVGQSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEKSVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQKRKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMGLHKLVVNFESDKLKAVKGFRNVIIGPA
GO Classification
process
physiological process
metabolism
macromolecule metabolism
biopolymer metabolism
biopolymer modification
protein modification
peptide cross-linking
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB04315 Guanosine-5'-Diphosphate

Associated as Enzyme

Id Name
DB00130 L-Glutamine

Associated as Prediction

Id Name
DB00082 Pegvisomant
DB00114 Pyridoxal Phosphate
DB00117 L-Histidine
DB00119 Pyruvic acid
DB00120 L-Phenylalanine
DB00123 L-Lysine
DB00125 L-Arginine
DB00128 L-Aspartic Acid
DB00130 L-Glutamine
DB00133 L-Serine
DB00134 L-Methionine
DB00135 L-Tyrosine
DB00138 L-Cystine
DB00142 L-Glutamic Acid
DB00145 Glycine
DB00149 L-Leucine
DB00150 L-Tryptophan
DB00151 L-Cysteine
DB00156 L-Threonine
DB00160 L-Alanine
DB00161 L-Valine
DB00167 L-Isoleucine
DB00171 Adenosine triphosphate
DB00172 L-Proline
DB00174 L-Asparagine
DB00279 Liothyronine
DB00300 Tenofovir
DB00466 Picrotoxin
DB00544 Fluorouracil
DB00709 Lamivudine
DB00718 Adefovir Dipivoxil
DB01119 Diazoxide
DB01212 Ceftriaxone
DB01235 Levodopa
DB01287 Dihydroergotoxine
DB01583 Liotrix
DB01746 D-Leucine
DB01786 D-Alanine
DB01839 1,2-Propanediol
DB01864 5'-Guanosine-Diphosphate-Monothiophosphate
DB01942 Formic Acid
DB01972 Guanosine-5'-Monophosphate
DB02059 Adenosine-5-Diphosphoribose
DB02109 Hadacidin
DB02142 Pyridoxamine-5'-Phosphate
DB02181 2'-Deoxyguanosine-5'-Triphosphate
DB02210 Hexane-1,6-Diol
DB02212 Pyrophosphate 2-
DB02340 N-Acetyl-Serine
DB02345 Selenocysteine
DB02493 Hydantocidin-5'-Phosphate
DB02547 Guanosine-5'-Diphosphate-Rhamnose
DB02556 D-Phenylalanine
DB02569 2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Diphosphate
DB02607 Adenosine Phosphonoacetic Acid
DB02666 (C8-R)-Hydantocidin 5'-Phosphate
DB02682 2-Deamino-6-Deoxy-6thiophosphite-5'-Phosphate Guanosine
DB02703 Fusidic Acid
DB02750 S-(Methylmercury)-L-Cysteine
DB02774 1,3-Propandiol
DB02836 Guanosine 5'-Diphosphate 2':3'-Cyclic Monophosphate
DB02887 2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Triphosphate
DB02952 Alpha-Aminoisobutyric Acid
DB02954 (Carboxyhydroxyamino)Ethanoic Acid
DB02975 Ge2270a
DB02994 Hydroxydimethylarsine Oxide
DB03103 Thymidine-5'- Diphosphate
DB03107 Beta-Alanine
DB03146 2-Deazo-6-Thiophosphate Guanosine-5'-Monophosphate
DB03152 B-2-Octylglucoside
DB03223 Diphthamide
DB03225 D-Tryptophan
DB03226 Trifluoroethanol
DB03431 Adenosine-5'-Diphosphate
DB03459 N-(Phosphonacetyl)-L-Aspartic Acid
DB03491 2'-Deoxyguanosine-5'-Diphosphate
DB03510 6-O-Phosphoryl Inosine Monophosphate
DB03793 Benzoic Acid
DB03839 D-Tyrosine
DB03929 D-Serine
DB04068 Fudp
DB04077 Glycerol
DB04083 N'-Pyridoxyl-Lysine-5'-Monophosphate
DB04121 Guanosine-3'-Monophosphate-5'-Diphosphate
DB04124 Aurodox
DB04137 Guanosine-5'-Triphosphate
DB04272 Citric Acid
DB04315 Guanosine-5'-Diphosphate
DB04366 3'-Deoxy 3'-Amino Adenosine-5'-Diphosphate
DB04398 Lactic Acid
DB04418 Adenylosuccinic Acid
DB04444 Tetrafluoroaluminate Ion
DB04460 (C8-S)-Hydantocidin 5'-Phosphate
DB04542 3'-Azido-3'-Deoxythymidine-5'-Diphosphate
DB04566 Inosinic Acid
DB06262 Droxidopa
DB07348 1,6,7,8,9,11A,12,13,14,14A-DECAHYDRO-1,13-DIHYDROXY-6-METHYL-4H-CYCLOPENT[F]OXACYCLOTRIDECIN-4-ONE
DB07690 (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID
DB07950 1H-INDOL-3-YLACETIC ACID
DB08185 2-METHYLTHIO-N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE
DB08231 MYRISTIC ACID
DB08348 N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE
DB08751 N,N'-DIMETHYL-N-(ACETYL)-N'-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)ETHYLENEDIAMINE
DB08794 Ethyl biscoumacetate
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