DT-Web

DB04315 - Guanosine-5'-Diphosphate


Identification
Name Guanosine-5'-Diphosphate
Accession Number DB04315 (EXPT01573)
Type small molecule
Description A guanine nucleotide containing two phosphate groups esterified to the sugar moiety. [PubChem]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 443.2005
Groups experimental
Monoisotopic Weight 443.024329371
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Adenylosuccinate synthetase isozyme 1
Name Adenylosuccinate synthetase isozyme 1
Gene Name ADSSL1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.7535
Elongation factor G
Name Elongation factor G
Gene Name fusA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.0605
Elongation factor Tu, mitochondrial
Name Elongation factor Tu, mitochondrial
Gene Name TUFM
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
GTP-binding protein engA
Name GTP-binding protein engA
Gene Name der
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.9931
GDP-mannose mannosyl hydrolase
Name GDP-mannose mannosyl hydrolase
Gene Name nudD
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.994
Probable GTP-binding protein engB
Name Probable GTP-binding protein engB
Gene Name engB
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.0533
Eukaryotic translation initiation factor 2 subunit 3
Name Eukaryotic translation initiation factor 2 subunit 3
Gene Name EIF2S3
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Guanine nucleotide-binding protein G(i) subunit alpha-1
Name Guanine nucleotide-binding protein G(i) subunit alpha-1
Gene Name GNAI1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Signal recognition particle protein
Name Signal recognition particle protein
Gene Name ffh
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.8818
Guanine nucleotide-binding protein G(t) subunit alpha-1
Name Guanine nucleotide-binding protein G(t) subunit alpha-1
Gene Name GNAT1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.0541
Elongation factor Tu-B
Name Elongation factor Tu-B
Gene Name tufB
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.8666
Ras-related protein Rab-9
Name Ras-related protein Rab-9
Gene Name RAB9A
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.918
Nucleoside diphosphate kinase A
Name Nucleoside diphosphate kinase A
Gene Name NME1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.6826
GTP-binding protein Rheb
Name GTP-binding protein Rheb
Gene Name RHEB
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Cell division control protein 42 homolog
Name Cell division control protein 42 homolog
Gene Name CDC42
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Elongation factor Tu
Name Elongation factor Tu
Gene Name tufA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.8635
ADP-ribosylation factor 1
Name ADP-ribosylation factor 1
Gene Name ARF1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.4181
Elongation factor 2
Name Elongation factor 2
Gene Name EEF2
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.3977
Putative GTP pyrophosphokinase
Name Putative GTP pyrophosphokinase
Gene Name relA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.4782
Ras-related protein Rap-2a
Name Ras-related protein Rap-2a
Gene Name RAP2A
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.0538
Elongation factor Tu GTP-binding domain-containing protein 1
Name Elongation factor Tu GTP-binding domain-containing protein 1
Gene Name EFTUD1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.0984
ADP-ribosylation factor-like protein 1
Name ADP-ribosylation factor-like protein 1
Gene Name ARL1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
GTP-binding nuclear protein Ran
Name GTP-binding nuclear protein Ran
Gene Name RAN
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Ras-related protein Rab-7a
Name Ras-related protein Rab-7a
Gene Name RAB7A
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Interferon-inducible GTPase 5
Name Interferon-inducible GTPase 5
Gene Name IRGC
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A
Name Eukaryotic peptide chain release factor GTP-binding subunit ERF3A
Gene Name GSPT1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Ras-related protein Rab-5A
Name Ras-related protein Rab-5A
Gene Name RAB5A
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
GTPase HRas
Name GTPase HRas
Gene Name HRAS
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.4711
Elongation factor 1-alpha 1
Name Elongation factor 1-alpha 1
Gene Name EEF1A1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Transforming protein RhoA
Name Transforming protein RhoA
Gene Name RHOA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.9954
ADP-ribosylation factor 4
Name ADP-ribosylation factor 4
Gene Name ARF4
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.9962
Protein-glutamine gamma-glutamyltransferase 2
Name Protein-glutamine gamma-glutamyltransferase 2
Gene Name TGM2
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.7397
GDP-mannose 4,6 dehydratase
Name GDP-mannose 4,6 dehydratase
Gene Name GMDS
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.8616
Ras-related protein Rab-11A
Name Ras-related protein Rab-11A
Gene Name RAB11A
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Ras-related protein Ral-A
Name Ras-related protein Ral-A
Gene Name RALA
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Adenylosuccinate synthetase
Name Adenylosuccinate synthetase
Gene Name purA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 2.47
Elongation factor Tu
Name Elongation factor Tu
Gene Name tuf
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.8635
ADP-ribosylation factor-like protein 5B
Name ADP-ribosylation factor-like protein 5B
Gene Name ARL5B
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Cell division protein ftsZ
Name Cell division protein ftsZ
Gene Name ftsZ
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.3312
Protein-glutamine gamma-glutamyltransferase E
Name Protein-glutamine gamma-glutamyltransferase E
Gene Name TGM3
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.1964
GTPase
Name GTPase
Gene Name rab6
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.9944
Ras-related protein Rab-8B
Name Ras-related protein Rab-8B
Gene Name RAB8B
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
ADP-ribosylation factor 6
Name ADP-ribosylation factor 6
Gene Name ARF6
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.3449
ADP-ribosylation factor-like protein 3
Name ADP-ribosylation factor-like protein 3
Gene Name ARL3
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Nucleoside diphosphate kinase B
Name Nucleoside diphosphate kinase B
Gene Name NME2
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.7489
GDP-mannose 4,6-dehydratase
Name GDP-mannose 4,6-dehydratase
Gene Name gca
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.9936
Ras-related C3 botulinum toxin substrate 1
Name Ras-related C3 botulinum toxin substrate 1
Gene Name RAC1
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.9954
Probable GTPase engC
Name Probable GTPase engC
Gene Name rsgA
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.9937
GTP-binding protein SAR1b
Name GTP-binding protein SAR1b
Gene Name SAR1B
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Adenylosuccinate synthetase
Name Adenylosuccinate synthetase
Gene Name Adss
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 2.47
ADP-ribosylation factor-like protein 5A
Name ADP-ribosylation factor-like protein 5A
Gene Name ARL5A
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.9945

Predictions


Id Partner name Gene Name Score
3323 Adenylosuccinate synthetase purA 2.47
3975 Adenylosuccinate synthetase ADSS 2.47
6817 Adenylosuccinate synthetase purA 2.47
3301 Cell division protein ftsZ ftsZ 1.3312
1673 GTP cyclohydrolase I GCH1 0.2084
3302 GTP cyclohydrolase I folE 0.2084
3209 Ornithine decarboxylase, inducible odcI 0.2082
2417 Chloramphenicol acetyltransferase cat 0.1956
3278 Chloramphenicol acetyltransferase cat 0.1956
3085 Molybdopterin-guanine dinucleotide biosynthesis protein A mobA 0.1914
2647 RNA-directed RNA polymerase P2 0.1897
3311 mRNA-capping enzyme A103R 0.1813
3381 Alcohol dehydrogenase Not Available 0.1568
4508 Alcohol dehydrogenase adhA 0.1568
866 Large neutral amino acids transporter small subunit 2 SLC7A8 0.1535
1750 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 PFKFB1 0.151
4534 Cytohesin-2 CYTH2 0.1447
2808 Chloramphenicol acetyltransferase 3 cat3 0.1353
864 Gag-Pol polyprotein gag-pol 0.1288
2237 Gag-Pol polyprotein gag-pol 0.1288
2326 Gag-Pol polyprotein gag-pol 0.1288
2451 Gag-Pol polyprotein gag-pol 0.1288
2901 Gag-Pol polyprotein gag-pol 0.1288
3165 Gag-Pol polyprotein gag-pol 0.1288
3722 Gag-Pol polyprotein gag-pol 0.1288
6306 Gag-Pol polyprotein gag-pol 0.1288
6624 Gag-Pol polyprotein gag-pol 0.1288
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.1221
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.1197
2281 Haloalkane dehalogenase linB 0.1186
6792 Poly [ADP-ribose] polymerase 15 PARP15 0.1123
6791 Hypothetical exotoxin A toxA 0.1123
2297 Genome polyprotein Not Available 0.1085
2322 Genome polyprotein Not Available 0.1085
2694 Genome polyprotein Not Available 0.1085
2719 Genome polyprotein Not Available 0.1085
2860 Genome polyprotein Not Available 0.1085
2928 Genome polyprotein Not Available 0.1085
3160 Genome polyprotein Not Available 0.1085
3260 Genome polyprotein Not Available 0.1085
4783 Genome polyprotein Not Available 0.1085
5726 Genome polyprotein Not Available 0.1085
5779 Genome polyprotein Not Available 0.1085
5867 Genome polyprotein Not Available 0.1085
6253 Genome polyprotein Not Available 0.1085
6301 Genome polyprotein Not Available 0.1085
6380 Genome polyprotein Not Available 0.1085
6381 Genome polyprotein Not Available 0.1085
6437 Genome polyprotein Not Available 0.1085
6520 Genome polyprotein Not Available 0.1085
6521 Genome polyprotein Not Available 0.1085
6652 Genome polyprotein Not Available 0.1085
6734 Genome polyprotein Not Available 0.1085
6735 Genome polyprotein Not Available 0.1085
6736 Genome polyprotein Not Available 0.1085
6737 Genome polyprotein Not Available 0.1085
6738 Genome polyprotein Not Available 0.1085
6739 Genome polyprotein Not Available 0.1085
6744 Genome polyprotein Not Available 0.1085
6748 Genome polyprotein Not Available 0.1085
6894 Genome polyprotein Not Available 0.1085
6898 Genome polyprotein Not Available 0.1085
3404 Exotoxin A eta 0.0978
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0935
822 Aldose reductase AKR1B1 0.0934
6552 Poly [ADP-ribose] polymerase 3 PARP3 0.0901
5793 Cytochrome c oxidase subunit 2 MT-CO2 0.0884
6559 Cytochrome c oxidase subunit 2 ctaC 0.0884
6669 Cytochrome c oxidase subunit 2 ctaC 0.0884
6557 Lactaldehyde dehydrogenase aldA 0.0883
371 Cytochrome c oxidase subunit 1 MT-CO1 0.0883
6558 Cytochrome c oxidase subunit 1 ctaD 0.0883
702 UMP-CMP kinase CMPK1 0.0881
517 Alcohol dehydrogenase 1C ADH1C 0.0815
291 Nitric-oxide synthase, endothelial NOS3 0.0797
4615 Chain A, Red Copper Protein Nitrosocyanin NE0143 0.0784
2892 Acetylglutamate kinase argB 0.0779
3550 Acetylglutamate kinase argB 0.0779
3669 Ribokinase rbsK 0.0778
4990 PpcA ppcA 0.077
3799 Hypoxanthine phosphoribosyltransferase hpt 0.076
3719 Inosine-5'-monophosphate dehydrogenase guaB 0.076
6390 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 ATP2A1 0.0744
2164 Multidrug resistance-associated protein 4 ABCC4 0.0734
6395 Myosin-14 MYH14 0.0723
2283 Steroid Delta-isomerase ksi 0.071
2920 Steroid Delta-isomerase ksi 0.071
2540 Choloylglycine hydrolase cbh 0.0709
3307 Acriflavine resistance protein B acrB 0.0709
342 P protein [Includes: DNA-directed DNA polymerase P 0.0708
612 P protein [Includes: DNA-directed DNA polymerase P 0.0708
2751 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0697
4755 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0697
6142 Solute carrier family 22 member 8 SLC22A8 0.0676
4269 Hypoxanthine-guanine phosphoribosyltransferase, putative HGPRTase 0.0675
2633 Anaerobic ribonucleoside-triphosphate reductase NRDD 0.0662
776 Bile salt export pump ABCB11 0.0661
1729 Solute carrier family 22 member 6 SLC22A6 0.0592
2638 Formate dehydrogenase H fdhF 0.0571
4593 ADP compounds hydrolase nudE nudE 0.0562
3617 Non-heme chloroperoxidase cpo 0.0544
5426 Non-heme chloroperoxidase cpo 0.0544
3014 Ribonuclease UK114 HRSP12 0.0544
3718 Hydrogen peroxide-inducible genes activator oxyR 0.0544
5428 Replication protein repA 0.0544
5427 Hydroxyquinol 1,2-dioxygenase chqB 0.0544
3018 HTH-type transcriptional regulator malT malT 0.0543
2460 ADP-ribose pyrophosphatase nudF 0.0489
4349 ADP-ribose pyrophosphatase ndx4 0.0489
3725 Lactaldehyde reductase fucO 0.0489
3108 CDP-glucose 4,6-dehydratase rfbG 0.0489
3067 Aquaporin Z aqpZ 0.0482
6320 Aquaporin Z aqpZ 0.0482
6500 Phospholipase A2 PLA2G1B 0.0477
2958 Probable tautomerase ydcE pptA 0.0474
3603 Chlorocatechol 1,2-dioxygenase clcA 0.0474
2573 Cocaine esterase cocE 0.0473
7263 Cocaine esterase Not Available 0.0473
6147 Solute carrier family 22 member 3 SLC22A3 0.0457
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0441
2748 Cysteine desulfurase sufS 0.0433
3971 CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase CAD 0.0432
3986 Protein-glutamine gamma-glutamyltransferase 6 TGM6 0.0424
3983 Protein-glutamine gamma-glutamyltransferase 5 TGM5 0.0424
3992 Protein-glutamine gamma-glutamyltransferase Z TGM7 0.0423
3988 Protein-glutamine gamma-glutamyltransferase K TGM1 0.0422
3990 Protein-glutamine gamma-glutamyltransferase 4 TGM4 0.0422
1008 CTP synthase 1 CTPS 0.0421
3985 Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2 GFPT2 0.0421
3989 Glutaminyl-tRNA synthetase QARS 0.0421
6385 H subunit of photosynthetic reaction center complex puhA 0.042
6388 Cytochrome c1 petC 0.0419
6387 Ubiquinol-cytochrome c reductase iron-sulfur subunit petA 0.0419
1227 Cytochrome b MT-CYB 0.0419
6386 Cytochrome b petB 0.0419
6937 Cytochrome b MT-CYB 0.0419
3023 DNA polymerase I, thermostable polA 0.0418
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0407
2769 P-hydroxybenzoate hydroxylase pobA 0.0407
2809 P-hydroxybenzoate hydroxylase pobA 0.0407
2300 Lysozyme E 0.0389
3633 Lysozyme R 0.0389
5597 Lysozyme 17 0.0389
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0385
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0385
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0385
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0385
1119 Peroxiredoxin-5, mitochondrial PRDX5 0.0379
6 Coagulation factor XIII A chain F13A1 0.0375
4553 Bifunctional adenosylcobalamin biosynthesis protein cobU cobU 0.0373
2693 Heat-labile enterotoxin B chain eltB 0.0369
4674 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase cumD 0.0368
6720 30S ribosomal protein Thx rpsU 0.0363
6709 30S ribosomal protein S16 rpsP 0.0363
6711 30S ribosomal protein S18 rpsR 0.0363
6708 30S ribosomal protein S15 rpsO 0.0363
6209 30S ribosomal protein S19 rpsS 0.0363
6712 30S ribosomal protein S19 rpsS 0.0363
6726 30S ribosomal protein S19 rpsS 0.0363
6716 30S ribosomal protein S6 rpsF 0.0363
6710 30S ribosomal protein S17 rpsQ 0.0363
6721 30S ribosomal protein S17 rpsQ 0.0363
6713 30S ribosomal protein S20 rpsT 0.0363
6722 30S ribosomal protein S20 rpsT 0.0363
6707 30S ribosomal protein S14 type Z rpsZ 0.0363
6208 30S ribosomal protein S13 rpsM 0.0363
6706 30S ribosomal protein S13 rpsM 0.0363
6717 30S ribosomal protein S7 rpsG 0.0363
7170 30S ribosomal protein S7 rpsG 0.0363
6715 30S ribosomal protein S5 rpsE 0.0363
22 30S ribosomal protein S4 rpsD 0.0363
6714 30S ribosomal protein S4 rpsD 0.0363
140 30S ribosomal protein S9 rpsI 0.0362
6719 30S ribosomal protein S9 rpsI 0.0362
6725 30S ribosomal protein S9 rpsI 0.0362
6705 30S ribosomal protein S11 rpsK 0.0362
308 30S ribosomal protein S12 rpsL 0.0362
6704 30S ribosomal protein S12 rpsL 0.0362
6724 30S ribosomal protein S3 rpsC 0.0362
6728 30S ribosomal protein S3 rpsC 0.0362
7168 30S ribosomal protein S3 rpsC 0.0362
6718 30S ribosomal protein S8 rpsH 0.0362
7169 30S ribosomal protein S8 rpsH 0.0362
6723 30S ribosomal protein S2 rpsB 0.0362
6727 30S ribosomal protein S2 rpsB 0.0362
6645 D-amino-acid oxidase DAO 0.0359
242 Asparagine synthetase [glutamine-hydrolyzing] ASNS 0.0356
6136 Multidrug resistance-associated protein 5 ABCC5 0.0356
6148 Multidrug resistance-associated protein 7 ABCC10 0.0355
3984 Probable glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial PET112L 0.0346
5 Glutaminase liver isoform, mitochondrial GLS2 0.0346
917 Glutaminase kidney isoform, mitochondrial GLS 0.0346
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0346
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0346
3991 Glutamine-dependent NAD(+) synthetase NADSYN1 0.0346
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.0346
5261 Phosphoribosylformylglycinamidine synthase purL 0.0346
1152 Glycogen phosphorylase, muscle form PYGM 0.0345
263 Neutral amino acid transporter B(0) SLC1A5 0.0343
413 Amidophosphoribosyltransferase PPAT 0.0337
2515 Amidophosphoribosyltransferase purF 0.0337
3714 Amidophosphoribosyltransferase purF 0.0337
2516 GMP reductase 1 GMPR 0.0332
2361 Response regulator pleD pleD 0.0332
4106 Guanylate kinase GUK1 0.0317
4516 Guanylate kinase gmk 0.0317
301 Kynurenine--oxoglutarate transaminase 1 CCBL1 0.0312
314 System N amino acid transporter 1 SLC38A3 0.031
677 Choline-phosphate cytidylyltransferase A PCYT1A 0.0276
2207 Rhodopsin RHO 0.0275
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0275
4533 Glyoxalase family protein BC_1747 0.027
2966 PyrR bifunctional protein [Includes: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase pyrR 0.0266
338 DNA polymerase UL30 0.0266
379 DNA polymerase UL54 0.0266
697 DNA polymerase ORF28 0.0266
2482 DNA polymerase 43 0.0266
4104 DNA polymerase BALF5 0.0266
176 30S ribosomal protein S10 rpsJ 0.0259
6175 30S ribosomal protein S10 rpsJ 0.0259
6151 Monocarboxylate transporter 10 SLC16A10 0.0254
3300 Xanthine phosphoribosyltransferase xpt 0.0251
3681 Xanthine phosphoribosyltransferase gpt 0.0251
3583 6-phosphogluconolactonase pgl 0.0249
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0246
871 Glucocorticoid receptor NR3C1 0.0238
5682 Ribonuclease pancreatic RNASE1 0.0234
2684 Histidine triad nucleotide-binding protein 1 HINT1 0.0234
738 Monocarboxylate transporter 1 SLC16A1 0.0234
6742 Recoverin RCVRN 0.0232
6752 Guanylyl cyclase-activating protein 1 GUCA1A 0.0232
6743 Non-fluorescent flavoprotein luxF 0.0232
394 Calcineurin subunit B isoform 1 PPP3R1 0.0232
6753 Apolipoprotein M APOM 0.0232
2528 Fatty acid metabolism regulator protein fadR 0.0232
6740 Fatty acid metabolism regulator protein fadR 0.0232
6747 Chalcone/stilbene synthase family protein MT1417 0.0232
6741 Peroxisomal 3,2-trans-enoyl-CoA isomerase PECI 0.0232
6751 Gag polyprotein gag 0.0232
6522 Hepatocyte nuclear factor 4-alpha HNF4A 0.0232
6746 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform PPP3CA 0.0232
6749 Polyprotein Not Available 0.0232
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0225
4773 Deoxycytidine kinase DCK 0.0223
6527 Lymphocyte antigen 96 LY96 0.0202
5961 Insulin INS 0.0202
6755 Poliovirus receptor PVR 0.0202
4200 Cytochrome P450 1A2 CYP1A2 0.0202
4545 Molybdopterin-converting factor subunit 2 moaE 0.02
2501 Protein ygbM ygbM 0.02
4037 Hypothetical protein GPX1 0.02
4297 Hypothetical protein SP_1951 0.02
4521 Hypothetical protein BC_2969 0.02
4540 Hypothetical protein TM_1070 0.02
4555 Hypothetical protein MT1739 0.02
4569 Hypothetical protein mshD 0.02
4578 Hypothetical protein PA3270 0.02
4747 Hypothetical protein PA3967 0.02
5177 Hypothetical protein TM_0096 0.02
5194 Hypothetical protein PA1204 0.02
5240 Hypothetical protein Rv2991 0.02
5370 Hypothetical protein TM_1158 0.02
5710 Hypothetical protein Tb927.5.1360 0.02
4514 Citrate lyase beta subunit-like protein citE 0.02
4781 Citrate lyase beta subunit-like protein DR_1240 0.02
4522 Arginine N-succinyltransferase subunit alpha astA 0.02
4527 Putative hydrolase ycdX ycdX 0.02
4536 Transcriptional regulator, IclR family TM_0065 0.02
4524 Mannose-6-phosphate isomerase yvyI 0.02
4547 Iron binding protein FbpA fbpA 0.02
4526 Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein TM_1223 0.02
4535 Glutaconyl-CoA decarboxylase subunit alpha gcdA 0.02
4538 Hypothetical protein VC1899 VC_1899 0.02
4529 Oxalate decarboxylase oxdC oxdC 0.02
4548 Gyrase B gyrB 0.02
4515 Peripheral plasma membrane protein CASK CASK 0.02
4546 Aminotransferase, putative TM_1131 0.02
658 Para-aminobenzoate synthase component 1 pabB 0.02
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.0194
5432 Trafficking protein particle complex subunit 3 TRAPPC3 0.0186
6524 Protein tonB tonB 0.0186
2616 Ganglioside GM2 activator GM2A 0.0176
2929 (S)-2-haloacid dehalogenase dhlB 0.0174
2995 (S)-2-haloacid dehalogenase Not Available 0.0174
4496 C-terminal-binding protein 1 CTBP1 0.0174
4528 Phenazine biosynthesis protein PhzD phzD1 0.0174
3759 Glutathione S-transferase gst 0.0174
4541 Glutathione S-transferase GST 0.0174
56 Delta-aminolevulinic acid dehydratase ALAD 0.0174
2356 Delta-aminolevulinic acid dehydratase hemB 0.0174
3613 Delta-aminolevulinic acid dehydratase hemB 0.0174
3674 Delta-aminolevulinic acid dehydratase hemB 0.0174
3237 Beta-lactamase OXA-2 bla 0.0174
4542 Glutaminase 1 glsA1 0.0174
4544 Glutaminase 1 glsA1 0.0174
4517 Probable butyrate kinase 2 buk2 0.0174
4532 Gephyrin GPHN 0.0174
2435 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0168
6613 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0168
2149 Angiogenin ANG 0.0165
4210 Toll-like receptor 4 TLR4 0.0162
3467 Methylglyoxal synthase mgsA 0.016
2230 Catalase CAT 0.016
3249 Catalase katA 0.016
3625 Catalase katA 0.016
4539 Catalase katA 0.016
4941 Catalase katB 0.016
4531 Putative ketoacyl reductase actIII 0.016
2775 Dihydroorotate dehydrogenase pyrD 0.016
3116 Bacterioferritin bfr 0.0156
4906 Bacterioferritin bfr 0.0156
4965 Bacterioferritin bfr 0.0156
3336 C4-dicarboxylate transport transcriptional regulatory protein dctD dctD 0.0156
5489 Ribonucleoside-diphosphate reductase 1 subunit beta nrdB 0.0156
3173 Enolase eno 0.0156
3709 Glycerol uptake facilitator protein glpF 0.0156
3238 Multidrug resistance protein mexA mexA 0.0156
3393 TGF-beta receptor type-2 TGFBR2 0.0156
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0154
2525 3-phosphoshikimate 1-carboxyvinyltransferase aroA 0.0151
3201 3-phosphoshikimate 1-carboxyvinyltransferase aroA 0.0151
2688 Peptide deformylase def 0.0145
2708 Peptide deformylase def 0.0145
3004 Peptide deformylase def 0.0145
4337 Peptide deformylase def 0.0145
4338 Peptide deformylase def 0.0145
5368 Peptide deformylase def 0.0145
5371 Peptide deformylase def 0.0145
6375 Peptide deformylase def 0.0145
6378 Peptide deformylase def 0.0145
6379 Peptide deformylase def 0.0145
6776 Peptide deformylase def 0.0145
6900 Peptide deformylase def 0.0145
2548 Subtilisin Carlsberg apr 0.014
2852 DNA mismatch repair protein mutL mutL 0.0136
862 Multidrug resistance-associated protein 1 ABCC1 0.0136
6144 Solute carrier family 22 member 2 SLC22A2 0.0133
1588 Multidrug resistance protein 1 ABCB1 0.0132
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0131
6085 Fatty acid-binding protein, intestinal FABP2 0.013
2427 Ferrichrome-iron receptor fhuA 0.013
6145 Solute carrier family 22 member 1 SLC22A1 0.0129
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0127
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0127
6459 Glycodelin PAEP 0.0126
768 FK506-binding protein 1A FKBP1A 0.0125
6228 Nuclear receptor coactivator 1 NCOA1 0.0124
3221 Cytochrome c4 cc4 0.0118
3191 Histidinol dehydrogenase hisD 0.0118
760 Fibroblast growth factor 1 FGF1 0.0118
6264 cAMP-dependent protein kinase inhibitor alpha PKIA 0.0118
810 Heme oxygenase 1 HMOX1 0.0117
3391 Heme oxygenase 1 pbsA1 0.0117
3027 Streptavidin Not Available 0.0116
3972 Adenylosuccinate synthetase isozyme 2 ADSS 0.0113
500 Monocarboxylate transporter 4 SLC16A3 0.0112
5598 Glycerol uptake operon antiterminator-related protein TM_1436 0.0111
4238 50S ribosomal protein L4 rplD 0.0111
5578 50S ribosomal protein L4 rplD 0.0111
6173 50S ribosomal protein L4 rplD 0.0111
6219 50S ribosomal protein L4 rplD 0.0111
2838 Ribose-5-phosphate isomerase A rpiA 0.0111
2952 Ribose-5-phosphate isomerase A rpiA 0.0111
5595 Ribose-5-phosphate isomerase A rpiA 0.0111
5590 N utilization substance protein B homolog nusB 0.0111
5577 N5-carboxyaminoimidazole ribonucleotide mutase purE 0.0111
5591 Complement component C8 gamma chain C8G 0.0111
3792 KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase eda 0.0111
5582 Regulator of transcription; stringent starvation protein A sspA 0.0111
5583 RNA 3'-terminal phosphate cyclase rtcA 0.0111
5060 Intron-associated endonuclease 1 ITEVIR 0.0111
5593 Transferase Not Available 0.0111
5588 Cell division protein FtsY TM_0570 0.0111
4695 UPF0124 protein yfiH yfiH 0.0111
5592 Ribonucleoside-diphosphate reductase subunit beta nrdF 0.0111
5587 Iron(III)-binding periplasmic protein fbpA 0.0111
5586 Pleckstrin homology domain-containing family A member 1 PLEKHA1 0.011
4375 Glutamine synthetase 1 glnA1 0.011
5575 Short tail fiber protein 12 0.011
5600 Pyruvate decarboxylase pdc 0.011
5580 Hexon protein PII 0.011
5574 Invasin YPTB1668 0.011
5581 Beta-fructosidase bfrA 0.011
2802 Endoglucanase G celCCG 0.0109
4692 A/G-specific adenine glycosylase mutY 0.0109
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0109
4311 tRNA TRDMT1 0.0109
4325 tRNA trmD 0.0109
4328 tRNA trmD 0.0109
533 Aminoacylase-1 ACY1 0.0101
209 Aspartoacylase ASPA 0.0101
3979 Aspartoacylase-2 ACY3 0.0101
3976 Aspartyl-tRNA synthetase, mitochondrial DARS2 0.0101
3969 Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole- succinocarboxamide synthase PAICS 0.0101
262 Calcium-binding mitochondrial carrier protein Aralar1 SLC25A12 0.0101
799 Aspartyl-tRNA synthetase, cytoplasmic DARS 0.0101
513 Calcium-binding mitochondrial carrier protein Aralar2 SLC25A13 0.0101
305 Mitochondrial aspartate-glutamate carrier protein SLC25A13 0.0101
76 Nitric-oxide synthase, brain NOS1 0.0101
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0096
3132 Tryptophan synthase alpha chain trpA 0.0096
6568 Tryptophan synthase alpha chain trpA 0.0096
5328 Prostaglandin F synthase Tb11.02.2310 0.0096
5006 RNASE4 protein RNASE4 0.0096
5599 3-carboxy-cis,cis-muconate cycloisomerase pcaB 0.0096
4992 Cytochrome c peroxidase Not Available 0.0096
3729 Citrate synthase gltA 0.0096
4575 Citrate synthase cit 0.0096
4580 Citrate synthase gltA 0.0096
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0096
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0096
2555 Pol polyprotein pol 0.0096
3242 Pol polyprotein gag-pol 0.0096
3471 Pol polyprotein gag-pro-pol 0.0096
5256 Pol polyprotein pol 0.0096
6469 Pol polyprotein gag-pol 0.0096
6565 Pol polyprotein Not Available 0.0096
2757 Inorganic pyrophosphatase ppa 0.0096
6238 Inorganic pyrophosphatase ppa 0.0096
6968 Inorganic pyrophosphatase PPA1 0.0096
2383 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0096
2937 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0096
4620 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0096
6594 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0096
6609 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0096
6646 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0096
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0093
465 Calmodulin CALM1 0.0093
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.009
2697 Uridine-cytidine kinase 2 UCK2 0.0089
1467 Tumor necrosis factor ligand superfamily member 13B TNFSF13B 0.0089
2603 Beta-lactamase II blm 0.0089
444 Alcohol dehydrogenase 1B ADH1B 0.0088
585 Aspartyl/asparaginyl beta-hydroxylase ASPH 0.0087
3977 ASRGL1 protein ASRGL1 0.0086
3486 Fumarate hydratase class II fumC 0.0084
2286 Isocitrate dehydrogenase [NADP] icd 0.0084
2302 Isocitrate dehydrogenase [NADP] icd 0.0084
2771 Isocitrate dehydrogenase [NADP] icd 0.0084
2869 1-deoxy-D-xylulose 5-phosphate reductoisomerase dxr 0.0084
2942 Sialidase nanH 0.0084
3546 Sialidase nedA 0.0084
857 Malate dehydrogenase, mitochondrial MDH2 0.0083
2755 Hypoxanthine-guanine-xanthine phosphoribosyltransferase LACZ 0.0083
2727 S-adenosylmethionine synthetase metK 0.0083
426 Aspartate aminotransferase, mitochondrial GOT2 0.0082
2805 Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 HS3ST3A1 0.008
740 Argininosuccinate synthase ASS1 0.0078
865 Argininosuccinate synthase ASS1 0.0078
2680 Argininosuccinate synthase argG 0.0078
3194 Argininosuccinate synthase argG 0.0078
3877 Growth-inhibiting protein 18 GIG18 0.0078
941 Betaine--homocysteine S-methyltransferase 1 BHMT 0.0078
1671 Excitatory amino acid transporter 3 SLC1A1 0.0077
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0077
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0077
1123 Eosinophil cationic protein RNASE3 0.0077
586 Aspartate aminotransferase, cytoplasmic GOT1 0.0077
332 Beta-lactamase blaZ 0.0077
2478 Beta-lactamase ampC 0.0077
2613 Beta-lactamase ampC 0.0077
2635 Beta-lactamase ampC 0.0077
2700 Beta-lactamase penP 0.0077
5445 Beta-lactamase blaB 0.0077
6019 Beta-lactamase SHV-7 0.0077
6701 Beta-lactamase cphA 0.0077
3010 Regulatory protein blaR1 blaR1 0.0077
2452 Tryptophanyl-tRNA synthetase trpS 0.0076
2434 NH(3)-dependent NAD(+) synthetase nadE 0.0074
2910 NH(3)-dependent NAD(+) synthetase nadE 0.0074
3217 NH(3)-dependent NAD(+) synthetase nadE 0.0074
357 Carbonic anhydrase 2 CA2 0.0074
5579 Carboxypeptidase B CPB1 0.0073
2885 Carboxyethyl-arginine beta-lactam-synthase bls 0.0073
4600 Malonamidase E2 Not Available 0.0072
3478 Glucose-1-phosphate thymidylyltransferase rmlA 0.0072
4277 Glucose-1-phosphate thymidylyltransferase rmlA 0.0072
3384 Macrophage migration inhibitory factor MIF 0.0071
904 Glutathione S-transferase P GSTP1 0.0071
411 Glycine N-methyltransferase GNMT 0.007
2717 Folylpolyglutamate synthase fgs 0.007
128 Adenine phosphoribosyltransferase APRT 0.0065
2428 Thiamine-phosphate pyrophosphorylase thiE 0.0065
587 Serum albumin ALB 0.0062
87 Hypoxanthine-guanine phosphoribosyltransferase HPRT1 0.0055
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0051
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0047
6013 Cytochrome P450 2E1 CYP2E1 0.0039
5304 UPF0166 protein TM_0021 TM_0021 0.0018
5314 UPF0079 ATP-binding protein HI0065 HI_0065 0.0018
3199 Phosphopantetheine adenylyltransferase coaD 0.0018
3543 Phosphopantetheine adenylyltransferase coaD 0.0018
3567 Phosphopantetheine adenylyltransferase coaD 0.0018
5289 Phosphopantetheine adenylyltransferase coaD 0.0018
5288 Shikimate kinase aroK 0.0018
5287 Signaling protein Not Available 0.0018
5259 Transcriptional regulator ntrC1 0.0018
6699 Transcriptional regulator Cgl2612 0.0018
5293 Shikimate kinase 2 aroL 0.0018
5292 Putative partitioning protein TT_C1605 0.0017
5290 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0017
5638 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0017
5270 ATP-dependent Clp protease ATP-binding subunit clpX clpX 0.0017
5266 Activator of hgdC 0.0017
5291 Glycogen synthase 1 glgA1 0.0017
2874 Nitrogenase iron protein 1 nifH1 0.0017
4346 Polynucleotide kinase pseT 0.0017
5264 DNA replication protein REP 0.0017
5283 D-alanine--D-alanine ligase B ddlB 0.0017
5281 Plasmid segregation protein parM parM 0.0017
5275 Multidrug resistance ABC transporter ATP-binding and permease protein lmrA 0.0017
5305 Phosphoribosylaminoimidazole carboxylase ATPase subunit purK 0.0017
1549 Heat shock 70 kDa protein 1 HSPA1A 0.0017
5299 D-alanine--D-alanine ligase ddl 0.0017
6598 D-alanine--D-alanine ligase ddl 0.0017
5284 Large T antigen Not Available 0.0017
5276 Chromosomal replication initiator protein dnaA dnaA 0.0017
3777 ATP-dependent Clp protease ATP-binding subunit clpA clpA 0.0017
5277 Preprotein translocase subunit secA secA 0.0017
5308 Preprotein translocase secA 1 subunit secA1 0.0017
4794 Phosphoenolpyruvate carboxykinase [ATP] pckA 0.0017
5285 Kinesin heavy chain KIF5B 0.0017
5315 Chaperone protein htpG htpG 0.0017
3390 Aminoglycoside 3'-phosphotransferase aphA 0.0015
6029 Aminoglycoside 3'-phosphotransferase aphA1 0.0015
4774 NTPase P4 Not Available 0.0015
5646 Galactokinase GALK1 0.0015
6277 Heat shock cognate 71 kDa protein HSPA8 0.0015
4837 Cag-alfa cag-alfa 0.0015
5265 FtsH ftsH 0.0015
4838 PMS1 protein homolog 2 PMS2 0.0015
5302 TrwB trwB 0.0015
4839 DNA polymerase III subunit tau dnaX 0.0015
2270 Dephospho-CoA kinase coaE 0.0015
5189 Trimethylamine dehydrogenase tmd 0.0015
2284 Adenylate kinase adk 0.0015
2296 Adenylate kinase adk 0.0015
2311 Adenylate kinase adk 0.0015
2312 Adenylate kinase Not Available 0.0015
3470 Hypothetical protein MG245 homolog MPN_348 0.0015
5295 2-keto-3-deoxy-gluconate kinase TT_P0036 0.0015
3426 Glutamine synthetase glnA 0.0015
3987 Glutamine synthetase GLUL 0.0015
3175 Glutamate--cysteine ligase gshA 0.0015
340 Apoptotic protease-activating factor 1 APAF1 0.0014
2683 Mono-ADP-ribosyltransferase C3 C3 0.0014
2390 Nonsecretory ribonuclease RNASE2 0.0014
5312 Kinesin-like protein KIF1A KIF1A 0.0014
2922 Glycerol kinase glpK 0.0013
5271 Focal adhesion kinase 1 PTK2 0.0013
2282 Protein recA recA 0.0013
2315 Protein recA recA 0.0013
2332 Protein recA recA 0.0013
5263 Protein recA recA 0.0013
2615 Chemotaxis protein cheA cheA 0.0013
2371 Pantothenate kinase coaA 0.0013
1881 Hexokinase-1 HK1 0.0013
2950 Inositol-trisphosphate 3-kinase A ITPKA 0.0013
825 Arsenical pump-driving ATPase ASNA1 0.0013
3435 Arsenical pump-driving ATPase arsA 0.0013
6857 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial PDK2 0.0013
5300 Antigen peptide transporter 1 TAP1 0.0012
408 Riboflavin kinase RFK 0.0012
6832 Serine/threonine-protein kinase SRPK2 SRPK2 0.0012
2817 Phosphoribosylglycinamide formyltransferase 2 purT 0.0012
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0012
788 Creatine kinase M-type CKM 0.0012
2334 Dethiobiotin synthetase bioD 0.0011
6555 Dethiobiotin synthetase bioD 0.0011
61 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0011
2644 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0011
2710 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0011
2511 MAP kinase-activated protein kinase 2 MAPKAPK2 0.0011
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.0011
2317 UDP-N-acetylmuramoylalanine--D-glutamate ligase murD 0.0011
2251 Thymidylate kinase tmk 0.001
2254 Thymidylate kinase DTYMK 0.001
3522 Thymidylate kinase tmk 0.001
48 Pyridoxal kinase PDXK 0.001
2091 Endoplasmin HSP90B1 0.001
1422 Serine/threonine-protein kinase 6 AURKA 0.001
3379 Kinesin-like protein KIF11 KIF11 0.001
3456 Heat shock protein HSP 90-beta HSP90AB1 0.001
207 Glutathione synthetase GSS 0.001
5269 Glutathione synthetase gshB 0.001
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.001
3822 Actin, alpha skeletal muscle ACTA1 0.001
509 Thymidine kinase TK 0.0009
570 Thymidine kinase TK 0.0009
2559 Thymidine kinase TK 0.0009
3430 Thymidine kinase tdk 0.0009
3518 Thymidine kinase TK 0.0009
5301 Thymidine kinase tdk 0.0009
5771 Thymidine kinase ORF36 0.0009
7009 Thymidine kinase ORF36 0.0009
504 Mast/stem cell growth factor receptor KIT 0.0009
1721 Glycogen synthase kinase-3 beta GSK3B 0.0009
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0008
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0008
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0008
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