DT-Web

Anaerobic ribonucleoside-triphosphate reductase


Partner ID 2633
Name Anaerobic ribonucleoside-triphosphate reductase
Synonyms 4551
Gene name NRDD
General function Nucleotide transport and metabolism
Specific function 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H(2)O = ribonucleoside triphosphate + thioredoxin
Gene sequence + ...

ATGACAATTGAAAAAGAAATTGAAGGATTAATTCATAAAACTAATAAAGACCTTTTAAACGAGAATGCTAATAAAGATTCTCGTGTTTTTCCAACTCAACGGGACCTTATGGCTGGTATTGTGTCTAAACACATTGCCAAAAATATGGTCCCGTCTTTTATTATGAAAGCGCATGAAAGCGGAATTATTCACGTGCATGATATTGATTATTCCCCTGCTCTTCCATTTACTAATTGCTGTTTAGTAGATTTAAAAGGAATGCTTGAAAACGGATTTAAGCTTGGTAATGCGCAGATTGAAACTCCTAAATCAATTGGAGTTGCTACTGCAATTATGGCACAAATTACTGCGCAAGTTGCTTCTCACCAATACGGCGGAACGACTTTTGCGAATGTAGATAAAGTACTTTCTCCTTATGTTAAACGCACCTATGCAAAACATATTGAGGATGCAGAAAAATGGCAAATCGCTGATGCGTTGAATTATGCTCAATCTAAAACAGAAAAAGACGTATACGATGCATTCCAAGCTTATGAGTATGAAGTGAACACGTTATTCAGTTCAAACGGACAGACTCCTTTTGTAACAATTACATTTGGTACGGGAACTGACTGGACTGAACGAATGATTCAGAAAGCAATTCTGAAAAATCGTATTAAAGGTCTTGGTCGTGATGGGATAACTCCTATTTTCCCTAAGCTTGTTATGTTCGTTGAAGAAGGTGTTAATCTTTATAAAGACGATCCGAACTATGATATTAAACAGCTTGCTCTAGAGTGCGCAAGCAAAAGGATGTATCCTGATATTATTTCAGCTAAGAACAATAAAGCTATCACTGGTTCATCTGTTCCTGTTTCTCCGATGGGTTGCCGTAGTTTCTTGAGCGTATGGAAAGATTCGACTGGCAATGAAATTCTTGATGGACGCAATAATCTTGGTGTTGTAACACTGAATCTTCCTCGCATCGCGTTAGATTCTTATATTGGAACACAGTTCAATGAACAGAAATTTGTTGAGCTATTTAATGAACGAATGGATTTATGTTTTGAAGCTTTGATGTGTAGAATTAGTTCCTTAAAAGGAGTTAAAGCTACTGTTGCTCCTATTCTTTACCAAGAAGGTGCATTCGGGGTTCGTCTTAAACCTGATGACGACATAATTGAGTTATTTAAAAACGGTAGAAGTTCAGTGTCTTTAGGATACATTGGTATTCACGAATTGAATATTCTTGTCGGTCGTGATATTGGACGAGAAATTTTAACTAAAATGAATGCTCATCTTAAACAGTGGACTGAAAGAACCGGATTTGCTTTTAGTTTATATTCGACTCCTGCTGAAAACCTGTGTTATCGCTTCTGTAAACTCGATACAGAAAAATATGGAAGCGTAAAAGATGTTACCGATAAAGGCTGGTACACTAACAGTTTCCATGTTTCAGTAGAAGAAAATATTACTCCGTTTGAAAAGATTTCTCGTGAAGCGCCATATCATTTCATTGCGACAGGTGGTCACATTTCTTATGTTGAACTTCCTGATATGAAAAATAACTTAAAAGGTCTTGAGGCCGTGTGGGATTATGCTGCACAGCATTTAGATTATTTTGGTGTTAATATGCCAGTAGATAAATGTTTTACATGTGGAAGTACCCATGAAATGACTCCTACTGAAAACGGATTTGTTTGTTCTATTTGTGGAGAAACTGATCCTAAAAAGATGAATACCATAAGAAGAACATGTGGTTATTTGGGAAATCCGAACGAACGCGGATTTAATCTCGGTAAAAATAAAGAAATCATGCATAGGGTTAAGCACCAATGA
Protein sequence + ...

MTIEKEIEGLIHKTNKDLLNENANKDSRVFPTQRDLMAGIVSKHIAKNMVPSFIMKAHESGIIHVHDIDYSPALPFTNCCLVDLKGMLENGFKLGNAQIETPKSIGVATAIMAQITAQVASHQYGGTTFANVDKVLSPYVKRTYAKHIEDAEKWQIADALNYAQSKTEKDVYDAFQAYEYEVNTLFSSNGQTPFVTITFGTGTDWTERMIQKAILKNRIKGLGRDGITPIFPKLVMFVEEGVNLYKDDPNYDIKQLALECASKRMYPDIISAKNNKAITGSSVPVSPMGCRSFLSVWKDSTGNEILDGRNNLGVVTLNLPRIALDSYIGTQFNEQKFVELFNERMDLCFEALMCRISSLKGVKATVAPILYQEGAFGVRLKPDDDIIELFKNGRSSVSLGYIGIHELNILVGRDIGREILTKMNAHLKQWTERTGFAFSLYSTPAENLCYRFCKLDTEKYGSVKDVTDKGWYTNSFHVSVEENITPFEKISREAPYHFIATGGHISYVELPDMKNNLKGLEAVWDYAAQHLDYFGVNMPVDKCFTCGSTHEMTPTENGFVCSICGETDPKKMNTIRRTCGYLGNPNERGFNLGKNKEIMHRVKHQ
GO Classification
function
catalytic activity
process
physiological process
metabolism
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB02181 2'-Deoxyguanosine-5'-Triphosphate
DB02452 Thymidine-5'-Triphosphate
DB03222 2'-Deoxyadenosine 5'-Triphosphate
DB03258 2'-Deoxycytidine-5'-Triphosphate

Associated as Prediction

Id Name
DB00300 Tenofovir
DB00432 Trifluridine
DB00495 Zidovudine
DB00709 Lamivudine
DB00718 Adefovir Dipivoxil
DB00987 Cytarabine
DB01643 Thymidine-5'-Phosphate
DB01660 Adenosine-5'-Diphosphate Monothiophosphate
DB01692 Dithioerythritol
DB02181 2'-Deoxyguanosine-5'-Triphosphate
DB02212 Pyrophosphate 2-
DB02333 Deoxyuridine-5'-Triphosphate
DB02345 Selenocysteine
DB02452 Thymidine-5'-Triphosphate
DB02569 2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Diphosphate
DB02607 Adenosine Phosphonoacetic Acid
DB02843 Alpha-D-Glucose-1-Phosphate
DB02887 2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Triphosphate
DB03103 Thymidine-5'- Diphosphate
DB03152 B-2-Octylglucoside
DB03222 2'-Deoxyadenosine 5'-Triphosphate
DB03258 2'-Deoxycytidine-5'-Triphosphate
DB03280 P1-(5'-Adenosyl)P5-(5'-Thymidyl)Pentaphosphate
DB03431 Adenosine-5'-Diphosphate
DB03491 2'-Deoxyguanosine-5'-Diphosphate
DB03666 3'-Azido-3'-Deoxythymidine-5'-Monophosphate
DB03723 2'-Deoxy-Thymidine-Beta-L-Rhamnose
DB03751 2'deoxy-Thymidine-5'-Diphospho-Alpha-D-Glucose
DB03846 5-Hydroxymethyluridine-2'-Deoxy-5'-Monophosphate
DB04068 Fudp
DB04160 Diphosphate
DB04272 Citric Acid
DB04315 Guanosine-5'-Diphosphate
DB04355 Uridine-5'-Monophosphate Glucopyranosyl-Monophosphateester
DB04366 3'-Deoxy 3'-Amino Adenosine-5'-Diphosphate
DB04444 Tetrafluoroaluminate Ion
DB04485 Deoxythymidine
DB04542 3'-Azido-3'-Deoxythymidine-5'-Diphosphate
DB07479 (1S)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL
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