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Poly [ADP-ribose] polymerase 15


Partner ID 6792
Name Poly [ADP-ribose] polymerase 15
Synonyms 9028
Gene name PARP15
General function Involved in NAD+ ADP-ribosyltransferase activity
Specific function Transcriptional repressor. Has ADP-ribosyltransferase activity
Gene sequence + ...

ATGCACGGAGTTGCAGGTGTTACTTCCAGAGCCGGACGAGATCGGGAGGCGGGGAGCATGCTGCCGGCCGGGAACCGTGGGGCGCGGAAGGCCTCCCGGCGCTCTTCCTCCCGGAGTATGTCCAGAGACAACAAGTTCAGCAAGAAAGATTGTCTTTCAATCAGGAATGTTGTAGCTTCAATCCAAACCAAAGAAGGTCTGAATCTCAAGTTGATAAGTGGAGATGTTCTGTACATCTGGGCCGATGTCATTGTCAACAGCGTTCCCATGAATCTTCAGCTTGGAGGAGGACCACTATCTCGGGCATTTTTGCAGAAAGCTGGTCCCATGCTCCAGAAAGAGTTAGATGACAGAAGGCGGGAAACAGAGGAAAAAGTAGGTAACATATTCATGACAAGCGGCTGCAATCTGGACTGCAAAGCTGTGCTCCATGCTGTGGCTCCATACTGGAATAATGGAGCAGAGACTTCTTGGCAGATCATGGCAAATATAATCAAGAAATGTTTGACAACTGTAGAAGTGCTATCTTTCTCATCAATCACATTTCCCATGATTGGAACAGGAAGTTTGCAGTTTCCCAAAGCTGTTTTTGCTAAACTAATCCTTTCAGAAGTGTTCGAATACAGTAGCAGCACAAGGCCGATAACTAGCCCTTTACAAGAAGTCCACTTTCTGGTATATACAAATGACGATGAAGGCTGTCAGGCATTTTTAGATGAATTCACTAACTGGTCAAGAATAAATCCCAACAAGGCCAGGATTCCCATGGCAGGAGATACCCAAGGTGTGGTCGGGACTGTCTCTAAGCCTTGTTTCACAGCATATGAAATGAAAATCGGTGCAATTACTTTTCAGGTTGCTACTGGAGATATAGCCACTGAACAGGTAGATGTTATTGTAAACTCAACAGCAAGGACATTTAATCGGAAATCAGGTGTGTCAAGAGCTATTTTAGAAGGTGCTGGACAAGCTGTGGAAAGTGAATGTGCTGTACTAGCTGCACAGCCTCACAGAGATTTTATAATTACACCAGGTGGATGCTTAAAGTGCAAAATAATAATTCATGTTCCTGGGGGAAAAGATGTCAGGAAAACGGTCACCAGTGTTCTAGAAGAGTGTGAACAGAGGAAGTACACATCGGTTTCCCTTCCAGCCATTGGAACAGGAAATGCCGGAAAAAACCCTATCACAGTTGCTGATAACATAATCGATGCTATTGTAGACTTCTCATCACAACATTCCACCCCATCATTAAAAACAGTTAAAGTTGTCATTTTTCAACCTGAGCTGCTAAATATATTCTACGACAGCATGAAAAAAAGAGACCTCTCTGCATCACTGAACTTTCAGTCCACATTCTCCATGACTACATGTAATCTTCCTGAACACTGGACTGACATGAATCATCAGCTGTTTTGCATGGTCCAGCTAGAGCCAGGACAATCAGAATATAATACCATAAAGGACAAGTTCACCCGAACTTGTTCTTCCTACGCAATAGAGAAGATTGAGAGGATACAGAATGCATTTCTCTGGCAGAGCTACCAGGTAAAGAAAAGGCAAATGGATATCAAGAATGACCATAAGAATAATGAGAGACTCCTCTTCCATGGGACAGATGCAGACTCAGTGCCATATGTCAATCAGCACGGCTTTAATAGAAGTTGTGCTGGGAAAAATGCTGTATCCTATGGAAAAGGAACCTATTTTGCTGTGGATGCCAGTTATTCTGCCAAGGACACCTACTCCAAGCCAGACAGCAATGGGAGAAAGCACATGTACGTTGTGCGAGTACTTACTGGAGTCTTCACAAAGGGACGTGCAGGATTAGTCACCCCTCCACCCAAGAATCCTCACAATCCCACAGATCTCTTTGACTCAGTGACAAACAATACACGATCTCCAAAGCTATTTGTGGTATTCTTTGATAATCAGGCTTACCCAGAATATCTCATAACTTTCACGGCTTAA
Protein sequence + ...

MHGVAGVTSRAGRDREAGSMLPAGNRGARKASRRSSSRSMSRDNKFSKKDCLSIRNVVASIQTKEGLNLKLISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDRRRETEEKVGNIFMTSGCNLDCKAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSFSSITFPMIGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEGCQAFLDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGAITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFIITPGGCLKCKIIIHVPGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTCNLPEHWTDMNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFTA
GO Classification
component
organelle
membrane-bound organelle
intracellular membrane-bound organelle
nucleus
function
catalytic activity
transferase activity
transferase activity, transferring glycosyl groups
transferase activity, transferring pentosyl groups
NAD+ ADP-ribosyltransferase activity
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB08348 N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE

Associated as Prediction

Id Name
DB02059 Adenosine-5-Diphosphoribose
DB02701 Nicotinamide
DB03223 Diphthamide
DB04315 Guanosine-5'-Diphosphate
DB07677 2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one
DB08058 4-[3-(1,4-diazepan-1-ylcarbonyl)-4-fluorobenzyl]phthalazin-1(2H)-one
DB08348 N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE
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