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Hypoxanthine-guanine-xanthine phosphoribosyltransferase


Partner ID 2755
Name Hypoxanthine-guanine-xanthine phosphoribosyltransferase
Synonyms 274
Gene name LACZ
General function Nucleotide transport and metabolism
Specific function Works with guanine, hypoxanthine and xanthine
Gene sequence + ...

ATGCCAATACCAAATAATCCAGGAGCTGGTGAAAATGCCTTTGATCCCGTTTTCGTAAACGATGACGATGGTTATGACCTTGATTCTTTTATGATCCCTGCACATTATAAAAAATATCTTACCAAGGTCTTAGTTCCAAATGGTGTCATAAAAAACCGTATTGAGAAATTGGCTTATGATATTAAAAAGGTGTACAACAATGAAGAGTTTCATATTCTTTGTTTGTTGAAAGGTTCTCGTGGTTTTTTCACTGCTCTCTTAAAGCATTTAAGTAGAATACATAATTATAGTGCCGTTGAGACGTCCAAACCATTATTTGGAGAACACTACGTACGTGTGAAATCCTATTGTAATGACCAATCAACAGGTACATTAGAAATTGTAAGTGAAGATTTATCTTGTTTAAAAGGAAAACATGTATTAATTGTTGAAGATATTATTGATACTGGTAAAACATTAGTAAAGTTTTGTGAATACTTAAAGAAATTTGAAATAAAAACCGTTGCCATCGCTTGTCTTTTTATTAAAAGAACACCTTTGTGGAATGGTTTTAAAGCTGATTTCGTTGGATTCTCAATTCCTGATCACTTTGTTGTTGGTTATAGTTTAGACTATAATGAAATTTTCAGAGATCTTGACCATTGTTGTTTGGTTAATGATGAGGGAAAAAAGAAATATAAAGCAACTTCATTATAA
Protein sequence + ...

MPIPNNPGAGENAFDPVFVNDDDGYDLDSFMIPAHYKKYLTKVLVPNGVIKNRIEKLAYDIKKVYNNEEFHILCLLKGSRGFFTALLKHLSRIHNYSAVETSKPLFGEHYVRVKSYCNDQSTGTLEIVSEDLSCLKGKHVLIVEDIIDTGKTLVKFCEYLKKFEIKTVAIACLFIKRTPLWNGFKADFVGFSIPDHFVVGYSLDYNEIFRDLDHCCLVNDEGKKKYKATSL
GO Classification
component
cytoplasm
cell
intracellular
function
transferase activity, transferring pentosyl groups
hypoxanthine phosphoribosyltransferase activity
catalytic activity
transferase activity
transferase activity, transferring glycosyl groups
process
nucleobase, nucleoside, nucleotide and nucleic acid metabolism
nucleoside metabolism
physiological process
purine salvage
purine ribonucleoside salvage
metabolism
cellular metabolism
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB02075 (1s)-1(9-Deazahypoxanthin-9yl)1,4-Dideoxy-1,4-Imino-D-Ribitol-5-Phosphate
DB02212 Pyrophosphate 2-

Associated as Prediction

Id Name
DB00300 Tenofovir
DB00352 Thioguanine
DB00563 Methotrexate
DB00695 Furosemide
DB00709 Lamivudine
DB00718 Adefovir Dipivoxil
DB00789 Gadopentetate dimeglumine
DB00814 Meloxicam
DB00851 Dacarbazine
DB00867 Ritodrine
DB00920 Ketotifen
DB00993 Azathioprine
DB01033 Mercaptopurine
DB01632 Alpha-Phosphoribosylpyrophosphoric Acid
DB01788 4-Imino-5-Methidyl-2-Methylpyrimidine
DB01907 Nicotinamide-Adenine-Dinucleotide
DB01944 (S)-blebbistatin
DB01972 Guanosine-5'-Monophosphate
DB02075 (1s)-1(9-Deazahypoxanthin-9yl)1,4-Dideoxy-1,4-Imino-D-Ribitol-5-Phosphate
DB02076 6-Phosphogluconic Acid
DB02153 3-Sulfinoalanine
DB02175 Malonic acid
DB02181 2'-Deoxyguanosine-5'-Triphosphate
DB02212 Pyrophosphate 2-
DB02254 Trifluoro-thiamin phosphate
DB02301 5,10-Methylene-6-Hydrofolic Acid
DB02309 5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine
DB02345 Selenocysteine
DB02475 Deoxyguanidinoproclavaminic acid
DB02569 2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Diphosphate
DB02596 Alpha,Beta-Methyleneadenosine-5'-Triphosphate
DB02607 Adenosine Phosphonoacetic Acid
DB02649 3-Amino-3-Oxopropanoic Acid
DB02885 4-Imino-5-Methidyl-2-Trifluoromethylpyrimidine
DB02887 2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Triphosphate
DB02968 Penicillin G Acyl-Serine
DB03075 (Diphosphono)Aminophosphonic Acid
DB03088 Pyroglutamic Acid
DB03103 Thymidine-5'- Diphosphate
DB03126 Mant-Adp
DB03145 4-Methyl-5-Hydroxyethylthiazole Phosphate
DB03153 3h-Pyrazolo[4,3-D]Pyrimidin-7-Ol
DB03416 Thiamin Phosphate
DB03431 Adenosine-5'-Diphosphate
DB03491 2'-Deoxyguanosine-5'-Diphosphate
DB03530 Acylated Ceftazidime
DB03755 Adenosine-5'-[Beta, Gamma-Methylene]Tetraphosphate
DB03801 Lysine Nz-Carboxylic Acid
DB03909 Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate
DB03962 Nicotinamide 8-Bromo-Adenine Dinucleotide Phosphate
DB04068 Fudp
DB04099 Deamido-Nad+
DB04137 Guanosine-5'-Triphosphate
DB04189 N2-(Carboxyethyl)-L-Arginine
DB04272 Citric Acid
DB04315 Guanosine-5'-Diphosphate
DB04356 9-Deazaguanine
DB04366 3'-Deoxy 3'-Amino Adenosine-5'-Diphosphate
DB04395 Phosphoaminophosphonic Acid-Adenylate Ester
DB04444 Tetrafluoroaluminate Ion
DB04542 3'-Azido-3'-Deoxythymidine-5'-Diphosphate
DB04554 8-Bromoadenosine-5'-Diphosphate
DB07468 (3aS)-3a-hydroxy-5-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one
DB07469 (3aS)-3a-hydroxy-7-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one
DB07470 (3aS)-3a-hydroxy-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one
DB07782 4-AMINO-2-TRIFLUOROMETHYL-5-HYDROXYMETHYLPYRIMIDINE PYROPHOSPHATE
DB08276 N-METHYL O-NITROPHENYL AMINOETHYLDIPHOSPHATE BERYLLIUM TRIFLUORIDE
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