DT-Web

DB03530 - Acylated Ceftazidime


Identification
Name Acylated Ceftazidime
Accession Number DB03530 (EXPT00836)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 469.492
Groups experimental
Monoisotopic Weight 469.072589367
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Regulatory protein blaR1
Name Regulatory protein blaR1
Gene Name blaR1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.7402
Beta-lactamase
Name Beta-lactamase
Gene Name ampC
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.7885

Predictions


Id Partner name Gene Name Score
332 Beta-lactamase blaZ 1.7885
2613 Beta-lactamase ampC 1.7885
2635 Beta-lactamase ampC 1.7885
2700 Beta-lactamase penP 1.7885
5445 Beta-lactamase blaB 1.7885
6019 Beta-lactamase SHV-7 1.7885
6701 Beta-lactamase cphA 1.7885
3466 Beta-lactam-inducible penicillin-binding protein pbp 0.2837
4629 Beta-lactamase CTX-M-9a blaCTX-M-9a 0.0803
2757 Inorganic pyrophosphatase ppa 0.0393
6238 Inorganic pyrophosphatase ppa 0.0393
6968 Inorganic pyrophosphatase PPA1 0.0393
2383 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0393
2937 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0393
4620 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0393
6594 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0393
6609 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0393
6646 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0393
2858 Beta-lactamase TEM bla 0.0383
6396 Beta-lactamase TEM bla 0.0383
4553 Bifunctional adenosylcobalamin biosynthesis protein cobU cobU 0.0342
2755 Hypoxanthine-guanine-xanthine phosphoribosyltransferase LACZ 0.0342
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0342
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0342
2647 RNA-directed RNA polymerase P2 0.0342
4812 Extended-spectrum beta-lactamase CTX-M-14 blaCTX-M-14 0.0316
2149 Angiogenin ANG 0.0316
2434 NH(3)-dependent NAD(+) synthetase nadE 0.0298
2910 NH(3)-dependent NAD(+) synthetase nadE 0.0298
3217 NH(3)-dependent NAD(+) synthetase nadE 0.0298
4600 Malonamidase E2 Not Available 0.0298
2885 Carboxyethyl-arginine beta-lactam-synthase bls 0.0298
2727 S-adenosylmethionine synthetase metK 0.0285
2717 Folylpolyglutamate synthase fgs 0.0285
2428 Thiamine-phosphate pyrophosphorylase thiE 0.0266
6395 Myosin-14 MYH14 0.0253
3195 Beta-lactamase Toho-1 bla 0.0244
5294 Nucleoside diphosphate kinase A NME1 0.0209
87 Hypoxanthine-guanine phosphoribosyltransferase HPRT1 0.0208
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.018
645 Penicillin-binding protein 1A mrcA 0.0152
5805 Penicillin-binding protein 1A ponA 0.0152
6185 Penicillin-binding protein 1A mrcA 0.0152
6799 Penicillin-binding protein 1A pbpA 0.0152
4252 Penicillin-binding protein 5 dacA 0.0082
633 Penicillin-binding proteins 1A/1B pbpA 0.0067
159 Penicillin-binding protein 2B penA 0.0066
6121 Penicillin-binding protein 2B penA 0.0066
4810 Beta-glucosidase bgl3 0.0061
4816 Orange carotenoid-binding protein Not Available 0.0061
4748 Levansucrase sacB 0.0061
4817 Sucrose porin scrY 0.0061
4818 Beta-lactamase CTX-M-27 blaCTX-M-27 0.0061
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0057
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0055
4813 Heme oxygenase hmuO 0.0053
5769 Heme oxygenase Not Available 0.0053
4814 Copper transport protein ATOX1 ATOX1 0.0053
2780 Septum formation protein Maf maf 0.0053
587 Serum albumin ALB 0.0049
3367 GDP-mannose 6-dehydrogenase algD 0.0049
4811 Amylosucrase ams 0.0049
1729 Solute carrier family 22 member 6 SLC22A6 0.0048
2617 Nitric oxide synthase oxygenase nos 0.0046
2701 Nitric oxide synthase oxygenase nos 0.0046
2461 D-alanyl-D-alanine carboxypeptidase Not Available 0.0038
5756 D-alanyl-D-alanine carboxypeptidase dac 0.0038
3822 Actin, alpha skeletal muscle ACTA1 0.0036
543 Penicillin-binding protein 1B mrcB 0.0027
6186 Penicillin-binding protein 1B ponB 0.0027
6822 Penicillin-binding protein 1b pbp1b 0.0027
6844 Penicillin-binding protein 1b pbp1b 0.0027
1024 Solute carrier family 22 member 11 SLC22A11 0.0022
6143 Solute carrier family 22 member 7 SLC22A7 0.0021
118 Organic cation/carnitine transporter 2 SLC22A5 0.002
6142 Solute carrier family 22 member 8 SLC22A8 0.0019
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