DT-Web

GDP-mannose 4,6-dehydratase


Partner ID 5627
Name GDP-mannose 4,6-dehydratase
Synonyms 7524
Gene name gca
General function Involved in catalytic activity
Specific function GDP-mannose = GDP-4-dehydro-6-deoxy-D-mannose + H(2)O
Gene sequence + ...

ATGACAAGAAGTGCACTGGTAACTGGGATCACCGGTCAGGACGGAGCGTACCTGGCCAAGCTGCTGCTGGAGAAGGGCTACCGGGTCCACGGCCTGGTGGCGCGGCGCAGCAGCGACACGCGCTGGCGCCTGCGCGAACTGGGGATCGAAGGCGATATCCAGTACGAGGACGGCGACATGGCCGATGCCTGTTCGGTGCAGCGCGCGGTGATCAAGGCGCAGCCGCAGGAGGTCTACAACCTGGCGGCACAGAGCTTCGTCGGGGCCTCCTGGAACCAGCCGGTGACCACCGGCGTCGTCGACGGCCTGGGCGTGACCCACCTGCTCGAGGCGATCCGCCAGTTCAGCCCGGAAACGCGCTTCTACCAGGCTTCCACCAGCGAGATGTTCGGCCTGATCCAGGCCGAGCGCCAGGACGAGAACACGCCGTTCTACCCGCGCAGCCCCTACGGCGTGGTCAAGCTCTATGGCCACTGGATCACCGTCAACTATCGCGAGAACTTCGGCCTGCACGCCTCCAGCGGCATCCTGTTCAACCACGAATCGCCGCTGCGCGGCATCGAGTTCGTCACGCGCAAGGTTACCGACGCGGTGGCCCGCATCAAGCTCGGCAAGCAGCAGGAATTGCGCCTGGGCAACGTCGACGTCAAGCGCGACTGGGGCTTTGGCGGGGACTACGTCGAAGCCATGTGGCTGATGTTGCAGCAGGACAAGGCCGACGACTACGTGGTGGCCACCGTTGTCACTACCACCGTGCGCGACATGTGCCAGATCGCTTTCGAGCATGTGGGCCTGGACTACCGCGACTTCCTCAAGATCGACCCGGCGTTCTTCCGGCCCGCCGAGGTCGACGTGCTGCTGGGTAATCCGGCCAAGGCCCAGCGTGTGCTCGGCTGGAAGCCCAGGACCAGCCTGGACGAGCTGATCCGGATGATGGTCGAGGCGGACCTGCGACGCGTTTCCCGGGAGTAG
Protein sequence + ...

MTRSALVTGITGQDGAYLAKLLLEKGYRVHGLVARRSSDTRWRLRELGIEGDIQYEDGDMADACSVQRAVIKAQPQEVYNLAAQSFVGASWNQPVTTGVVDGLGVTHLLEAIRQFSPETRFYQASTSEMFGLIQAERQDENTPFYPRSPYGVAKLYGHWITVNYRESFGLHASSGILFNHESPLRGIEFVTRKVTDAVARIKLGKQQELRLGNVDAKRDWGFAGDYVEAMWLMLQQDKADDYVVATGVTTTVRDMCQIAFEHVGLDYRDFLKIDPAFFRPAEVDVLLGNPAKAQRVLGWKPRTSLDELIRMMVEADLRRVSRE
GO Classification
function
carbon-oxygen lyase activity
hydro-lyase activity
NAD binding
binding
GDP-mannose 4,6-dehydratase activity
catalytic activity
lyase activity
cofactor binding
coenzyme binding
process
nucleobase, nucleoside, nucleotide and nucleic acid metabolism
nucleotide-sugar metabolism
physiological process
metabolism
cellular metabolism
biosynthesis
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB04315 Guanosine-5'-Diphosphate

Associated as Prediction

Id Name
DB00128 L-Aspartic Acid
DB00130 L-Glutamine
DB00300 Tenofovir
DB00709 Lamivudine
DB00718 Adefovir Dipivoxil
DB01864 5'-Guanosine-Diphosphate-Monothiophosphate
DB01942 Formic Acid
DB01972 Guanosine-5'-Monophosphate
DB02059 Adenosine-5-Diphosphoribose
DB02109 Hadacidin
DB02181 2'-Deoxyguanosine-5'-Triphosphate
DB02210 Hexane-1,6-Diol
DB02212 Pyrophosphate 2-
DB02345 Selenocysteine
DB02493 Hydantocidin-5'-Phosphate
DB02547 Guanosine-5'-Diphosphate-Rhamnose
DB02569 2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Diphosphate
DB02607 Adenosine Phosphonoacetic Acid
DB02666 (C8-R)-Hydantocidin 5'-Phosphate
DB02682 2-Deamino-6-Deoxy-6thiophosphite-5'-Phosphate Guanosine
DB02703 Fusidic Acid
DB02750 S-(Methylmercury)-L-Cysteine
DB02774 1,3-Propandiol
DB02836 Guanosine 5'-Diphosphate 2':3'-Cyclic Monophosphate
DB02887 2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Triphosphate
DB02954 (Carboxyhydroxyamino)Ethanoic Acid
DB02975 Ge2270a
DB02994 Hydroxydimethylarsine Oxide
DB03103 Thymidine-5'- Diphosphate
DB03146 2-Deazo-6-Thiophosphate Guanosine-5'-Monophosphate
DB03152 B-2-Octylglucoside
DB03223 Diphthamide
DB03226 Trifluoroethanol
DB03431 Adenosine-5'-Diphosphate
DB03491 2'-Deoxyguanosine-5'-Diphosphate
DB03510 6-O-Phosphoryl Inosine Monophosphate
DB03793 Benzoic Acid
DB04068 Fudp
DB04077 Glycerol
DB04121 Guanosine-3'-Monophosphate-5'-Diphosphate
DB04124 Aurodox
DB04137 Guanosine-5'-Triphosphate
DB04272 Citric Acid
DB04315 Guanosine-5'-Diphosphate
DB04366 3'-Deoxy 3'-Amino Adenosine-5'-Diphosphate
DB04418 Adenylosuccinic Acid
DB04444 Tetrafluoroaluminate Ion
DB04460 (C8-S)-Hydantocidin 5'-Phosphate
DB04542 3'-Azido-3'-Deoxythymidine-5'-Diphosphate
DB04566 Inosinic Acid
DB07348 1,6,7,8,9,11A,12,13,14,14A-DECAHYDRO-1,13-DIHYDROXY-6-METHYL-4H-CYCLOPENT[F]OXACYCLOTRIDECIN-4-ONE
DB07690 (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID
DB08185 2-METHYLTHIO-N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE
DB08231 MYRISTIC ACID
DB08348 N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE
DB08751 N,N'-DIMETHYL-N-(ACETYL)-N'-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)ETHYLENEDIAMINE
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