DT-Web

DB02682 - 2-Deamino-6-Deoxy-6thiophosphite-5'-Phosphate Guanosine


Identification
Name 2-Deamino-6-Deoxy-6thiophosphite-5'-Phosphate Guanosine
Accession Number DB02682 (EXPT02944)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 445.259
Groups experimental
Monoisotopic Weight 444.998411434
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Adenylosuccinate synthetase
Name Adenylosuccinate synthetase
Gene Name purA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.2977

Predictions


Id Partner name Gene Name Score
3323 Adenylosuccinate synthetase purA 1.2977
3975 Adenylosuccinate synthetase ADSS 1.2977
4598 Adenylosuccinate synthetase Adss 1.2977
6817 Adenylosuccinate synthetase purA 1.2977
3107 Putative GTP pyrophosphokinase relA 0.1246
3978 Adenylosuccinate synthetase isozyme 1 ADSSL1 0.0849
3799 Hypoxanthine phosphoribosyltransferase hpt 0.0338
3719 Inosine-5'-monophosphate dehydrogenase guaB 0.0337
4269 Hypoxanthine-guanine phosphoribosyltransferase, putative HGPRTase 0.0237
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0193
1152 Glycogen phosphorylase, muscle form PYGM 0.0153
1882 Ras-related C3 botulinum toxin substrate 1 RAC1 0.0082
3197 GDP-mannose mannosyl hydrolase nudD 0.0082
5630 ADP-ribosylation factor-like protein 5A ARL5A 0.0082
2170 Transforming protein RhoA RHOA 0.0082
5624 GTPase rab6 0.0082
5628 Probable GTPase engC rsgA 0.0082
5618 ADP-ribosylation factor 4 ARF4 0.0082
5627 GDP-mannose 4,6-dehydratase gca 0.0082
3366 GTP-binding protein engA der 0.0082
3354 Ras-related protein Rap-2a RAP2A 0.0071
3335 Probable GTP-binding protein engB engB 0.0071
3115 Ras-related protein Rab-9 RAB9A 0.0071
3396 Elongation factor Tu tufA 0.0071
5621 Elongation factor Tu tuf 0.0071
3261 Signal recognition particle protein ffh 0.0071
3170 Elongation factor Tu-B tufB 0.0071
3270 Elongation factor G fusA 0.0071
5619 GDP-mannose 4,6 dehydratase GMDS 0.0071
2521 Cell division protein ftsZ ftsZ 0.0066
3301 Cell division protein ftsZ ftsZ 0.0066
6750 ADP-ribosylation factor 6 ARF6 0.0066
6447 Guanine nucleotide-binding protein G(t) subunit alpha-1 GNAT1 0.0066
6556 Elongation factor Tu GTP-binding domain-containing protein 1 EFTUD1 0.0066
6790 Elongation factor 2 EEF2 0.0062
1758 GTPase HRas HRAS 0.0059
1596 Protein-glutamine gamma-glutamyltransferase 2 TGM2 0.0058
6316 ADP-ribosylation factor 1 ARF1 0.0055
2339 Protein-glutamine gamma-glutamyltransferase E TGM3 0.0055
5626 Nucleoside diphosphate kinase B NME2 0.0046
5294 Nucleoside diphosphate kinase A NME1 0.0044
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