DT-Web

DB04124 - Aurodox


Identification
Name Aurodox
Accession Number DB04124 (EXPT02115)
Type small molecule
Description Aurodox is an antibiotic obtained from a streptomyces variant considered as possibly effective against streptococcus pyogenes infections. It may promote growth in poultry.
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 810.9693
Groups experimental
Monoisotopic Weight 810.430275458
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Elongation factor Tu-B
Name Elongation factor Tu-B
Gene Name tufB
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.0303

Predictions


Id Partner name Gene Name Score
1882 Ras-related C3 botulinum toxin substrate 1 RAC1 0.0297
3197 GDP-mannose mannosyl hydrolase nudD 0.0297
5630 ADP-ribosylation factor-like protein 5A ARL5A 0.0297
5618 ADP-ribosylation factor 4 ARF4 0.0297
5628 Probable GTPase engC rsgA 0.0297
5624 GTPase rab6 0.0297
5627 GDP-mannose 4,6-dehydratase gca 0.0297
2170 Transforming protein RhoA RHOA 0.0296
3366 GTP-binding protein engA der 0.0296
3396 Elongation factor Tu tufA 0.0272
5621 Elongation factor Tu tuf 0.0272
3354 Ras-related protein Rap-2a RAP2A 0.0258
5619 GDP-mannose 4,6 dehydratase GMDS 0.0258
3335 Probable GTP-binding protein engB engB 0.0258
3115 Ras-related protein Rab-9 RAB9A 0.0258
3270 Elongation factor G fusA 0.0258
3261 Signal recognition particle protein ffh 0.0258
3107 Putative GTP pyrophosphokinase relA 0.0258
6750 ADP-ribosylation factor 6 ARF6 0.0238
6556 Elongation factor Tu GTP-binding domain-containing protein 1 EFTUD1 0.0238
2521 Cell division protein ftsZ ftsZ 0.0238
3301 Cell division protein ftsZ ftsZ 0.0238
6447 Guanine nucleotide-binding protein G(t) subunit alpha-1 GNAT1 0.0238
6790 Elongation factor 2 EEF2 0.0225
1758 GTPase HRas HRAS 0.0215
1596 Protein-glutamine gamma-glutamyltransferase 2 TGM2 0.0207
6316 ADP-ribosylation factor 1 ARF1 0.0201
2339 Protein-glutamine gamma-glutamyltransferase E TGM3 0.0198
3978 Adenylosuccinate synthetase isozyme 1 ADSSL1 0.0189
2632 Adenylosuccinate synthetase purA 0.0187
3323 Adenylosuccinate synthetase purA 0.0187
3975 Adenylosuccinate synthetase ADSS 0.0187
4598 Adenylosuccinate synthetase Adss 0.0187
6817 Adenylosuccinate synthetase purA 0.0187
5626 Nucleoside diphosphate kinase B NME2 0.0168
5294 Nucleoside diphosphate kinase A NME1 0.016
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