DT-Web

DB00151 - L-Cysteine


Identification
Name L-Cysteine
Accession Number DB00151 (DB04443, NUTR00018)
Type small molecule
Description A thiol-containing non-essential amino acid that is oxidized to form cystine. [PubChem]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 121.158
Groups approved
Monoisotopic Weight 121.019749163
Pharmacology
Indication For the prevention of liver damage and kidney damage associated with overdoses of acetaminophen
Mechanism of action Although classified as a non-essential amino acid cysteine may be essential for infants, the elderly, and individuals with certain metabolic disease or who suffer from malabsorption syndromes. Cysteine can usually be synthesized by the human body under normal physiological conditions if a sufficient quantity of methionine is available. Due to the ability of thiols to undergo redox reactions, cysteine has antioxidant properties. Cysteine's antioxidant properties are typically expressed in the tripeptide glutathione, which occurs in humans as well as other organisms. The systemic availability of oral glutathione (GSH) is negligible; so it must be biosynthesized from its constituent amino acids, cysteine, glycine, and glutamic acid. Glutamic acid and glycine are readily available in the diets of most industrialized countries, but the availability of cysteine can be the limiting substrate. Cysteine is also an important source of sulfide in human metabolism. The sulfide in iron-sulfur clusters and in nitrogenase is extracted from cysteine, which is converted to alanine in the process. In a 1994 report released by five top cigarette companies, cysteine is one of the 599 additives to cigarettes. Its use or purpose, however, is unknown, like most cigarette additives. Its inclusion in cigarettes could offer two benefits: Acting as an expectorant, since smoking increases mucus production in the lungs; and increasing the beneficial antioxidant glutathione (which is diminished in smokers).
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Glutamate--cysteine ligase regulatory subunit
Name Glutamate--cysteine ligase regulatory subunit
Gene Name GCLM
Pharmacological action unknown
Actions Not Available
References
  • Ashida H, Sawa Y, Shibata H: Cloning, biochemical and phylogenetic characterizations of gamma-glutamylcysteine synthetase from Anabaena sp. PCC 7120. Plant Cell Physiol. 2005 Apr;46(4):557-62. Epub 2005 Feb 2. - Pubmed
DTHybrid score 0.7089
Glutamate--cysteine ligase catalytic subunit
Name Glutamate--cysteine ligase catalytic subunit
Gene Name GCLC
Pharmacological action unknown
Actions Not Available
References
  • Ashida H, Sawa Y, Shibata H: Cloning, biochemical and phylogenetic characterizations of gamma-glutamylcysteine synthetase from Anabaena sp. PCC 7120. Plant Cell Physiol. 2005 Apr;46(4):557-62. Epub 2005 Feb 2. - Pubmed
  • Srivastava S, Chan C: Application of metabolic flux analysis to identify the mechanisms of free fatty acid toxicity to human hepatoma cell line. Biotechnol Bioeng. 2007 Jul 5;. - Pubmed
DTHybrid score 0.6218
Cysteine dioxygenase
Name Cysteine dioxygenase
Gene Name CDO-1
Pharmacological action unknown
Actions Not Available
References
  • Jin HF, DU SX, Zhao X, Zhang SQ, Tian Y, Bu DF, Tang CS, DU JB: [Significance of endogenous sulfur dioxide in the regulation of cardiovascular system] Beijing Da Xue Xue Bao. 2007 Aug 18;39(4):423-5. - Pubmed
  • Roopnarinesingh ES, Steventon GB, Harris RM, Waring RH, Mitchell SC: Induction of cysteine dioxygenase activity by oral administration of cysteine analogues to the rat: implications for drug efficacy and safety. Drug Metabol Drug Interact. 2005;21(2):75-86. - Pubmed
  • Ye S, Wu X, Wei L, Tang D, Sun P, Bartlam M, Rao Z: An insight into the mechanism of human cysteine dioxygenase. Key roles of the thioether-bonded tyrosine-cysteine cofactor. J Biol Chem. 2007 Feb 2;282(5):3391-402. Epub 2006 Nov 29. - Pubmed
  • McCoy JG, Bailey LJ, Bitto E, Bingman CA, Aceti DJ, Fox BG, Phillips GN Jr: Structure and mechanism of mouse cysteine dioxygenase. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3084-9. Epub 2006 Feb 21. - Pubmed
  • Pierce BS, Gardner JD, Bailey LJ, Brunold TC, Fox BG: Characterization of the nitrosyl adduct of substrate-bound mouse cysteine dioxygenase by electron paramagnetic resonance: electronic structure of the active site and mechanistic implications. Biochemistry. 2007 Jul 24;46(29):8569-78. Epub 2007 Jun 28. - Pubmed
DTHybrid score 0.8623
Aspartate aminotransferase, cytoplasmic
Name Aspartate aminotransferase, cytoplasmic
Gene Name GOT1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.6254
Cystathionine gamma-lyase
Name Cystathionine gamma-lyase
Gene Name CTH
Pharmacological action unknown
Actions Not Available
References
  • Fiorucci S, Antonelli E, Mencarelli A, Orlandi S, Renga B, Rizzo G, Distrutti E, Shah V, Morelli A: The third gas: H2S regulates perfusion pressure in both the isolated and perfused normal rat liver and in cirrhosis. Hepatology. 2005 Sep;42(3):539-48. - Pubmed
  • Zhang H, Zhi L, Moore PK, Bhatia M: Role of hydrogen sulfide in cecal ligation and puncture-induced sepsis in the mouse. Am J Physiol Lung Cell Mol Physiol. 2006 Jun;290(6):L1193-201. Epub 2006 Jan 20. - Pubmed
  • Wallace JL, Dicay M, McKnight W, Martin GR: Hydrogen sulfide enhances ulcer healing in rats. FASEB J. 2007 Jul 18;. - Pubmed
DTHybrid score 1.3535
Cystathionine beta-synthase
Name Cystathionine beta-synthase
Gene Name CBS
Pharmacological action unknown
Actions Not Available
References
  • Zhang H, Zhi L, Moore PK, Bhatia M: Role of hydrogen sulfide in cecal ligation and puncture-induced sepsis in the mouse. Am J Physiol Lung Cell Mol Physiol. 2006 Jun;290(6):L1193-201. Epub 2006 Jan 20. - Pubmed
  • Lowicka E, Beltowski J: Hydrogen sulfide (H2S) - the third gas of interest for pharmacologists. Pharmacol Rep. 2007 Jan-Feb;59(1):4-24. - Pubmed
  • Tamizhselvi R, Moore PK, Bhatia M: Hydrogen sulfide acts as a mediator of inflammation in acute pancreatitis: in vitro studies using isolated mouse pancreatic acinar cells. J Cell Mol Med. 2007 Mar-Apr;11(2):315-26. - Pubmed
  • Oh GS, Pae HO, Lee BS, Kim BN, Kim JM, Kim HR, Jeon SB, Jeon WK, Chae HJ, Chung HT: Hydrogen sulfide inhibits nitric oxide production and nuclear factor-kappaB via heme oxygenase-1 expression in RAW264.7 macrophages stimulated with lipopolysaccharide. Free Radic Biol Med. 2006 Jul 1;41(1):106-19. Epub 2006 Apr 25. - Pubmed
  • Bhatia M, Wong FL, Fu D, Lau HY, Moochhala SM, Moore PK: Role of hydrogen sulfide in acute pancreatitis and associated lung injury. FASEB J. 2005 Apr;19(6):623-5. Epub 2005 Jan 25. - Pubmed
DTHybrid score 0.6627
Cysteinyl-tRNA synthetase, cytoplasmic
Name Cysteinyl-tRNA synthetase, cytoplasmic
Gene Name CARS
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.8556
Methylated-DNA--protein-cysteine methyltransferase
Name Methylated-DNA--protein-cysteine methyltransferase
Gene Name MGMT
Pharmacological action unknown
Actions Not Available
References
  • Niture SK, Velu CS, Smith QR, Bhat GJ, Srivenugopal KS: Increased expression of the MGMT repair protein mediated by cysteine prodrugs and chemopreventative natural products in human lymphocytes and tumor cell lines. Carcinogenesis. 2007 Feb;28(2):378-89. Epub 2006 Aug 31. - Pubmed
DTHybrid score 1.47
Glutathione synthetase
Name Glutathione synthetase
Gene Name GSS
Pharmacological action unknown
Actions Not Available
References
  • Tanaka T, Halicka HD, Huang X, Traganos F, Darzynkiewicz Z: Constitutive histone H2AX phosphorylation and ATM activation, the reporters of DNA damage by endogenous oxidants. Cell Cycle. 2006 Sep;5(17):1940-5. Epub 2006 Sep 1. - Pubmed
DTHybrid score 0.8269
Thiamine transporter 2
Name Thiamine transporter 2
Gene Name SLC19A3
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.8554
Probable cysteinyl-tRNA synthetase, mitochondrial
Name Probable cysteinyl-tRNA synthetase, mitochondrial
Gene Name CARS2
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.8557
Cysteine sulfinic acid decarboxylase
Name Cysteine sulfinic acid decarboxylase
Gene Name CSAD
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Chan-Palay V, Lin CT, Palay S, Yamamoto M, Wu JY: Taurine in the mammalian cerebellum: demonstration by autoradiography with [3H]taurine and immunocytochemistry with antibodies against the taurine-synthesizing enzyme, cysteine-sulfinic acid decarboxylase. Proc Natl Acad Sci U S A. 1982 Apr;79(8):2695-9. - Pubmed
  • Guion-Rain M-C, Portemer C, Chatagner F: Rat liver cysteine sulfinate decarboxylase: purification, new appraisal of the molecular weight and determination of catalytic properties. Biochim Biophys Acta. 1975 Mar 28;384(1):265-76. - Pubmed
  • Daniels KM, Stipanuk MH: The effect of dietary cysteine level on cysteine metabolism in rats. J Nutr. 1982 Nov;112(11):2130-41. - Pubmed
DTHybrid score 0.6564
Cysteine desulfurase, mitochondrial
Name Cysteine desulfurase, mitochondrial
Gene Name NFS1
Pharmacological action unknown
Actions Not Available
References
  • You D, Wang L, Yao F, Zhou X, Deng Z: A novel DNA modification by sulfur: DndA is a NifS-like cysteine desulfurase capable of assembling DndC as an iron-sulfur cluster protein in Streptomyces lividans. Biochemistry. 2007 May 22;46(20):6126-33. Epub 2007 May 1. - Pubmed
  • Ding H, Harrison K, Lu J: Thioredoxin reductase system mediates iron binding in IscA and iron delivery for the iron-sulfur cluster assembly in IscU. J Biol Chem. 2005 Aug 26;280(34):30432-7. Epub 2005 Jun 28. - Pubmed
  • Ding B, Smith ES, Ding H: Mobilization of the iron centre in IscA for the iron-sulphur cluster assembly in IscU. Biochem J. 2005 Aug 1;389(Pt 3):797-802. - Pubmed
  • Yang J, Bitoun JP, Ding H: Interplay of IscA and IscU in biogenesis of iron-sulfur clusters. J Biol Chem. 2006 Sep 22;281(38):27956-63. Epub 2006 Jul 27. - Pubmed
  • Layer G, Ollagnier-de Choudens S, Sanakis Y, Fontecave M: Iron-sulfur cluster biosynthesis: characterization of Escherichia coli CYaY as an iron donor for the assembly of [2Fe-2S] clusters in the scaffold IscU. J Biol Chem. 2006 Jun 16;281(24):16256-63. Epub 2006 Apr 9. - Pubmed
DTHybrid score 0.6674
Cysteine dioxygenase type 1
Name Cysteine dioxygenase type 1
Gene Name CDO1
Pharmacological action unknown
Actions Not Available
References
  • Roopnarinesingh ES, Steventon GB, Harris RM, Waring RH, Mitchell SC: Induction of cysteine dioxygenase activity by oral administration of cysteine analogues to the rat: implications for drug efficacy and safety. Drug Metabol Drug Interact. 2005;21(2):75-86. - Pubmed
  • McCoy JG, Bailey LJ, Bitto E, Bingman CA, Aceti DJ, Fox BG, Phillips GN Jr: Structure and mechanism of mouse cysteine dioxygenase. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3084-9. Epub 2006 Feb 21. - Pubmed
  • Ye S, Wu X, Wei L, Tang D, Sun P, Bartlam M, Rao Z: An insight into the mechanism of human cysteine dioxygenase. Key roles of the thioether-bonded tyrosine-cysteine cofactor. J Biol Chem. 2007 Feb 2;282(5):3391-402. Epub 2006 Nov 29. - Pubmed
  • Jin HF, DU SX, Zhao X, Zhang SQ, Tian Y, Bu DF, Tang CS, DU JB: [Significance of endogenous sulfur dioxide in the regulation of cardiovascular system] Beijing Da Xue Xue Bao. 2007 Aug 18;39(4):423-5. - Pubmed
DTHybrid score 0.6335

Transporters


Monocarboxylate transporter 10
Name Monocarboxylate transporter 10
Gene Name SLC16A10
Actions inhibitor
References
  • Kim DK, Kanai Y, Chairoungdua A, Matsuo H, Cha SH, Endou H: Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters. J Biol Chem. 2001 May 18;276(20):17221-8. Epub 2001 Feb 20. - Pubmed
DTHybrid score 0.7093

Predictions


Id Partner name Gene Name Score
5269 Glutathione synthetase gshB 0.8269
6501 Fatty acid-binding protein, liver FABP1 0.1625
2748 Cysteine desulfurase sufS 0.1593
1243 Cathepsin D CTSD 0.1455
349 Serine--pyruvate aminotransferase AGXT 0.0959
184 L-serine dehydratase SDS 0.0764
491 Serine palmitoyltransferase 1 SPTLC1 0.0763
431 Serine racemase SRR 0.0763
727 Serine palmitoyltransferase 2 SPTLC2 0.0763
735 Alanine aminotransferase 1 GPT 0.0723
3904 Alanine aminotransferase 2 GPT2 0.0723
114 Alanine--glyoxylate aminotransferase 2, mitochondrial AGXT2 0.0677
3899 Alanine--glyoxylate aminotransferase 2-like 2 AGXT2L2 0.0672
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0635
3877 Growth-inhibiting protein 18 GIG18 0.0624
574 Branched-chain-amino-acid aminotransferase, cytosolic BCAT1 0.0619
435 Kynureninase KYNU 0.0603
4654 Kynureninase kynU 0.0603
72 Seryl-tRNA synthetase, cytoplasmic SARS 0.0584
763 Tyrosine aminotransferase TAT 0.0567
5493 Tyrosine aminotransferase Not Available 0.0567
426 Aspartate aminotransferase, mitochondrial GOT2 0.0547
795 Branched-chain-amino-acid aminotransferase, mitochondrial BCAT2 0.0499
2823 Trypanothione reductase TPR 0.0494
532 Neutral amino acid transporter A SLC1A4 0.048
4070 Probable alanyl-tRNA synthetase, mitochondrial AARS2 0.0479
323 Alanyl-tRNA synthetase, cytoplasmic AARS 0.0479
420 Glutamate decarboxylase 1 GAD1 0.0474
3900 Glutamate decarboxylase 1 GAD1 0.0474
665 Phosphoserine aminotransferase PSAT1 0.0474
4652 Phosphoserine aminotransferase serC 0.0474
801 Kynurenine/alpha-aminoadipate aminotransferase mitochondrial AADAT 0.0474
3895 Kynurenine--oxoglutarate transaminase 3 CCBL2 0.0474
330 Spermidine synthase SRM 0.0463
3038 Spermidine synthase speE 0.0463
866 Large neutral amino acids transporter small subunit 2 SLC7A8 0.0459
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0446
334 S-adenosylmethionine synthetase isoform type-2 MAT2A 0.0441
2537 Aromatic-amino-acid aminotransferase tyrB 0.0434
411 Glycine N-methyltransferase GNMT 0.043
2249 Aspartate aminotransferase aspC 0.043
2671 Aspartate aminotransferase aspC 0.043
5490 Aspartate aminotransferase Not Available 0.043
534 Threonine synthase-like 1 THNSL1 0.0429
1566 Corticoliberin CRH 0.0413
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.0408
914 Formimidoyltransferase-cyclodeaminase FTCD 0.0395
3 Histidine decarboxylase HDC 0.039
242 Asparagine synthetase [glutamine-hydrolyzing] ASNS 0.0387
301 Kynurenine--oxoglutarate transaminase 1 CCBL1 0.037
575 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial GCAT 0.0369
455 5-aminolevulinate synthase, nonspecific, mitochondrial ALAS1 0.0369
681 Glycine dehydrogenase [decarboxylating], mitochondrial GLDC 0.0369
593 Proton-coupled amino acid transporter 1 SLC36A1 0.0359
3908 P-selectin cytoplasmic tail-associated protein pcap 0.0337
1671 Excitatory amino acid transporter 3 SLC1A1 0.0335
3915 Cysteine sulfinic acid decarboxylase-related protein 1 CSAD 0.0332
3885 Hypothetical protein DKFZp686P09201 DKFZp686P09201 0.0328
3884 SHMT2 protein SHMT2 0.0328
3901 SHMT2 protein SHMT2 0.0328
3879 Serine hydroxymethyltransferase 2 Not Available 0.0328
321 Serine hydroxymethyltransferase, mitochondrial SHMT2 0.0328
3896 CDNA FLJ46802 fis, clone TRACH3032150, moderately similar to Cysteine sulfinic acid decarboxylase GADL1 0.0322
113 S-adenosylmethionine decarboxylase proenzyme AMD1 0.032
3878 GAD1 protein GAD1 0.032
3881 Selenocysteine lyase variant Not Available 0.032
306 Pyridoxal phosphate phosphatase PDXP 0.032
3891 Putative L-Dopa decarboxylase DDC 0.032
3911 Uncharacterized protein C20orf38 SPTLC3 0.032
3887 Phosphorylase PYGB 0.032
3914 Alanine-glyoxylate aminotransferase homolog TLH6 0.032
3883 Ornithine aminotransferase variant Not Available 0.032
3909 Hepatic peroxysomal alanine:glyoxylate aminotransferase Not Available 0.032
3893 DDC protein DDC 0.032
3906 Serine dehydratase-like SDSL 0.0319
855 Sphingosine-1-phosphate lyase 1 SGPL1 0.0319
3880 Serine hydroxymethyltransferase 1 Not Available 0.0319
3910 O-phosphoseryl-tRNA(Sec) selenium transferase SEPSECS 0.0319
3903 Aminolevulinate, delta-, synthase 2 ALAS2 0.0319
3905 Molybdenum cofactor sulfurase MOCOS 0.0319
3886 Migration-inducing protein 4 ALAS1 0.0319
3894 KIAA0251 protein PDXDC1 0.0319
3882 Brain glycogen phosphorylase variant Not Available 0.0319
3875 Glycogen phosphorylase, brain form PYGB 0.0319
499 Arginine decarboxylase ADC 0.0318
3876 Aromatic-L-amino-acid decarboxylase DDC 0.031
3874 Proline synthetase co-transcribed bacterial homolog protein PROSC 0.03
2532 Pantoate--beta-alanine ligase panC 0.0285
899 Glutathione S-transferase Mu 3 GSTM3 0.0285
905 Glutathione transferase omega-1 GSTO1 0.0285
367 Serine hydroxymethyltransferase, cytosolic SHMT1 0.0281
4077 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform PPP2CB 0.0274
375 SEC14-like protein 3 SEC14L3 0.0274
86 SEC14-like protein 4 SEC14L4 0.0274
4076 Diacylglycerol kinase alpha DGKA 0.0274
4025 Mitochondrial glutamate carrier 1 SLC25A22 0.0264
4022 Glutamate--ammonia ligase domain-containing protein 1 LGSN 0.0264
1047 Excitatory amino acid transporter 2 SLC1A2 0.0264
4024 Mitochondrial glutamate carrier 2 SLC25A18 0.0264
4026 Aspartyl aminopeptidase DNPEP 0.0264
4021 Probable glutamyl-tRNA synthetase, mitochondrial EARS2 0.0264
4023 N-acetylglutamate synthase, mitochondrial NAGS 0.0264
1912 Excitatory amino acid transporter 1 SLC1A3 0.0264
4016 Excitatory amino acid transporter 5 SLC1A7 0.0264
4019 Excitatory amino acid transporter 4 SLC1A6 0.0264
664 Glutamate decarboxylase 2 GAD2 0.0264
3890 Glutamate decarboxylase 2 GAD2 0.0264
4020 Glutamyl aminopeptidase ENPEP 0.0264
915 Delta 1-pyrroline-5-carboxylate synthetase ALDH18A1 0.0264
922 Glutamate receptor 4 GRIA4 0.0264
920 Glutamate receptor, ionotropic kainate 5 GRIK5 0.0264
4018 Glutamate receptor delta-2 subunit GRID2 0.0264
926 Metabotropic glutamate receptor 7 GRM7 0.0264
927 Metabotropic glutamate receptor 8 GRM8 0.0264
924 Glutamate receptor, ionotropic kainate 3 GRIK3 0.0264
919 Glutamate receptor, ionotropic kainate 4 GRIK4 0.0264
4027 Glutamate receptor delta-1 subunit GRID1 0.0264
4017 5-oxoprolinase OPLAH 0.0264
925 Metabotropic glutamate receptor 4 GRM4 0.0264
3913 Glutamic acid decarboxylase GAD65 0.0259
199 Monocarboxylate transporter 8 SLC16A2 0.0258
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.025
3977 ASRGL1 protein ASRGL1 0.0247
5 Glutaminase liver isoform, mitochondrial GLS2 0.0245
3984 Probable glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial PET112L 0.0245
6645 D-amino-acid oxidase DAO 0.0245
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0245
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0245
3991 Glutamine-dependent NAD(+) synthetase NADSYN1 0.0245
917 Glutaminase kidney isoform, mitochondrial GLS 0.0245
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.0245
5261 Phosphoribosylformylglycinamidine synthase purL 0.0245
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0244
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.024
472 Ornithine aminotransferase, mitochondrial OAT 0.0239
3810 Catechol O-methyltransferase COMT 0.0236
33 Cystine/glutamate transporter SLC7A11 0.0235
203 Pyridoxine-5'-phosphate oxidase PNPO 0.0234
5925 Neuropeptide Y NPY 0.0231
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.023
314 System N amino acid transporter 1 SLC38A3 0.0229
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.0228
283 SEC14-like protein 2 SEC14L2 0.0227
708 Alpha-tocopherol transfer protein TTPA 0.0216
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0207
810 Heme oxygenase 1 HMOX1 0.0204
3391 Heme oxygenase 1 pbsA1 0.0204
3932 Glutathione S-transferase A2 GSTA2 0.0203
449 Ornithine decarboxylase ODC1 0.0201
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0201
4078 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform PPP2CA 0.0201
4069 Threonyl-tRNA synthetase, mitochondrial TARS2 0.0197
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0197
261 Threonyl-tRNA synthetase, cytoplasmic TARS 0.0197
246 Valyl-tRNA synthetase VARS 0.0196
997 Protein kinase C beta type PRKCB 0.0195
625 Glutamate carboxypeptidase 2 FOLH1 0.0194
738 Monocarboxylate transporter 1 SLC16A1 0.0186
210 Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase EPRS 0.0184
916 Metabotropic glutamate receptor 1 GRM1 0.0183
1970 Protein kinase C alpha type PRKCA 0.0182
2632 Adenylosuccinate synthetase purA 0.0182
3323 Adenylosuccinate synthetase purA 0.0182
3975 Adenylosuccinate synthetase ADSS 0.0182
4598 Adenylosuccinate synthetase Adss 0.0182
6817 Adenylosuccinate synthetase purA 0.0182
3972 Adenylosuccinate synthetase isozyme 2 ADSS 0.0181
209 Aspartoacylase ASPA 0.0181
533 Aminoacylase-1 ACY1 0.0181
3969 Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole- succinocarboxamide synthase PAICS 0.0181
3979 Aspartoacylase-2 ACY3 0.0181
799 Aspartyl-tRNA synthetase, cytoplasmic DARS 0.0181
3976 Aspartyl-tRNA synthetase, mitochondrial DARS2 0.0181
513 Calcium-binding mitochondrial carrier protein Aralar2 SLC25A13 0.0181
305 Mitochondrial aspartate-glutamate carrier protein SLC25A13 0.0181
262 Calcium-binding mitochondrial carrier protein Aralar1 SLC25A12 0.0181
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0178
10 Glycogen phosphorylase, liver form PYGL 0.0175
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0173
923 Glutamate receptor 3 GRIA3 0.0173
904 Glutathione S-transferase P GSTP1 0.0171
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.017
740 Argininosuccinate synthase ASS1 0.0169
865 Argininosuccinate synthase ASS1 0.0169
2680 Argininosuccinate synthase argG 0.0169
3194 Argininosuccinate synthase argG 0.0169
5469 Head decoration protein shp 0.0168
3971 CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase CAD 0.0166
275 Arachidonate 5-lipoxygenase ALOX5 0.0162
2457 Bacillolysin nprS 0.016
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0158
601 Propionyl-CoA carboxylase beta chain, mitochondrial PCCB 0.0157
6013 Cytochrome P450 2E1 CYP2E1 0.0156
585 Aspartyl/asparaginyl beta-hydroxylase ASPH 0.0154
676 Tyrosine 3-monooxygenase TH 0.0149
815 Histidyl-tRNA synthetase, cytoplasmic HARS 0.0147
96 Histidine ammonia-lyase HAL 0.0147
6257 Histidine ammonia-lyase Not Available 0.0147
6536 Histidine ammonia-lyase hutH 0.0147
2461 D-alanyl-D-alanine carboxypeptidase Not Available 0.0147
5756 D-alanyl-D-alanine carboxypeptidase dac 0.0147
705 Glutamate receptor 1 GRIA1 0.0147
482 Glycine receptor subunit alpha-1 GLRA1 0.0146
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0142
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0142
38 Cystinosin CTNS 0.0141
3998 B(0,+)-type amino acid transporter 1 SLC7A9 0.0141
1963 Neutral and basic amino acid transport protein rBAT SLC3A1 0.0141
150 Cationic amino acid transporter 3 SLC7A3 0.0137
235 High-affinity cationic amino acid transporter 1 SLC7A1 0.0137
58 Cationic amino acid transporter 4 SLC7A4 0.0137
471 Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) SLC6A14 0.0134
1152 Glycogen phosphorylase, muscle form PYGM 0.0132
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.013
399 Tyrosyl-tRNA synthetase, mitochondrial YARS2 0.0127
263 Neutral amino acid transporter B(0) SLC1A5 0.0119
4058 Glycine N-acyltransferase-like protein 2 GLYATL2 0.0115
4057 Glycine N-acyltransferase GLYAT 0.0115
4061 Peroxisomal sarcosine oxidase PIPOX 0.0115
4056 N-arachidonyl glycine receptor GPR18 0.0115
4055 Bile acid CoA:amino acid N-acyltransferase BAAT 0.0115
4059 Glycine N-acyltransferase-like protein 1 GLYATL1 0.0115
4060 Vesicular inhibitory amino acid transporter SLC32A1 0.0115
1088 5-aminolevulinate synthase, erythroid-specific, mitochondrial ALAS2 0.0115
1236 Sodium- and chloride-dependent glycine transporter 1 SLC6A9 0.0115
4062 Sodium- and chloride-dependent glycine transporter 2 SLC6A5 0.0115
1466 Glycyl-tRNA synthetase GARS 0.0115
3978 Adenylosuccinate synthetase isozyme 1 ADSSL1 0.0115
701 Isoleucine-tRNA synthetase IARS 0.011
546 Isoleucyl-tRNA synthetase, cytoplasmic IARS 0.011
4080 Isoleucyl-tRNA synthetase, mitochondrial IARS2 0.011
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.011
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0109
221 Lysyl-tRNA synthetase KARS 0.0109
4092 Probable asparaginyl-tRNA synthetase, mitochondrial NARS2 0.0107
669 Asparaginyl-tRNA synthetase, cytoplasmic NARS 0.0107
5682 Ribonuclease pancreatic RNASE1 0.0102
5650 NimA-related protein DR_0842 0.0101
921 Glutamate receptor 2 GRIA2 0.0099
5646 Galactokinase GALK1 0.0099
5265 FtsH ftsH 0.0099
3390 Aminoglycoside 3'-phosphotransferase aphA 0.0099
6029 Aminoglycoside 3'-phosphotransferase aphA1 0.0099
5302 TrwB trwB 0.0099
501 Leucine carboxyl methyltransferase 1 LCMT1 0.0097
675 Leucine carboxyl methyltransferase 2 LCMT2 0.0097
846 Leucyl-tRNA synthetase, cytoplasmic LARS 0.0097
227 Probable leucyl-tRNA synthetase, mitochondrial LARS2 0.0097
42 Phenylalanyl-tRNA synthetase alpha chain FARSA 0.0096
6602 Phenylalanyl-tRNA synthetase alpha chain pheS 0.0096
31 Phenylalanyl-tRNA synthetase, mitochondrial FARS2 0.0096
618 Phenylalanyl-tRNA synthetase beta chain FARSB 0.0096
6603 Phenylalanyl-tRNA synthetase beta chain pheT 0.0096
619 Low-affinity cationic amino acid transporter 2 SLC7A2 0.0095
4054 Glycine cleavage system H protein, mitochondrial GCSH 0.0094
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0093
828 Phenylalanine-4-hydroxylase PAH 0.0092
3109 Phenylalanine-4-hydroxylase phhA 0.0092
62 Glycine receptor subunit beta GLRB 0.0091
256 Tyrosyl-tRNA synthetase, cytoplasmic YARS 0.0089
5312 Kinesin-like protein KIF1A KIF1A 0.0088
500 Monocarboxylate transporter 4 SLC16A3 0.0087
489 Monocarboxylate transporter 2 SLC16A7 0.0086
383 Glycine amidinotransferase, mitochondrial GATM 0.0085
2892 Acetylglutamate kinase argB 0.0083
3550 Acetylglutamate kinase argB 0.0083
2371 Pantothenate kinase coaA 0.0082
2950 Inositol-trisphosphate 3-kinase A ITPKA 0.0081
825 Arsenical pump-driving ATPase ASNA1 0.0081
3435 Arsenical pump-driving ATPase arsA 0.0081
2615 Chemotaxis protein cheA cheA 0.0081
1881 Hexokinase-1 HK1 0.0081
6832 Serine/threonine-protein kinase SRPK2 SRPK2 0.0079
3254 Bifunctional protein putA [Includes: Proline dehydrogenase putA 0.0077
2727 S-adenosylmethionine synthetase metK 0.0077
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0076
110 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.0075
461 Glycine receptor subunit alpha-3 GLRA3 0.0075
820 Glycine receptor subunit alpha-2 GLRA2 0.0075
833 Organic cation/carnitine transporter 1 SLC22A4 0.0075
2817 Phosphoribosylglycinamide formyltransferase 2 purT 0.0074
90 Tryptophan 5-hydroxylase 2 TPH2 0.0073
4063 Tryptophanyl-tRNA synthetase, mitochondrial WARS2 0.0073
4034 Glutaredoxin-1 GLRX 0.0072
4037 Hypothetical protein GPX1 0.0072
4297 Hypothetical protein SP_1951 0.0072
4521 Hypothetical protein BC_2969 0.0072
4540 Hypothetical protein TM_1070 0.0072
4555 Hypothetical protein MT1739 0.0072
4569 Hypothetical protein mshD 0.0072
4578 Hypothetical protein PA3270 0.0072
4747 Hypothetical protein PA3967 0.0072
5177 Hypothetical protein TM_0096 0.0072
5194 Hypothetical protein PA1204 0.0072
5240 Hypothetical protein Rv2991 0.0072
5370 Hypothetical protein TM_1158 0.0072
5710 Hypothetical protein Tb927.5.1360 0.0072
4038 Glutathione peroxidase 4 GPX4 0.0072
1975 Phospholipid hydroperoxide glutathione peroxidase, mitochondrial GPX4 0.0072
4035 Glutathione S-transferase Mu 5 GSTM5 0.0072
1928 Leukotriene C4 synthase LTC4S 0.0072
4029 Microsomal glutathione S-transferase 3 MGST3 0.0072
4032 Microsomal glutathione S-transferase 1 MGST1 0.0072
906 Glutathione peroxidase 1 GPX1 0.0072
4043 Glutaredoxin-2, mitochondrial GLRX2 0.0072
4030 Thioredoxin domain-containing protein 12 TXNDC12 0.0072
4033 S-formylglutathione hydrolase ESD 0.0072
4039 CDNA FLJ23636 fis, clone CAS07176 GPX8 0.0072
4036 Glutathione peroxidase 6 GPX6 0.0072
900 Glutathione S-transferase A4 GSTA4 0.0072
903 Glutathione S-transferase A5 GSTA5 0.0072
911 Glutathione peroxidase 3 GPX3 0.0072
4040 Glutathione peroxidase 7 GPX7 0.0072
907 Glutathione peroxidase 2 GPX2 0.0072
910 Epididymal secretory glutathione peroxidase GPX5 0.0072
4042 Glutathione transferase omega-2 GSTO2 0.0072
1056 Gamma-glutamyltranspeptidase 1 GGT1 0.0072
714 Glutathione reductase, mitochondrial GSR 0.007
5641 Rod shape-determining protein MreB TM_0588 0.007
4178 DNA repair protein RAD51 homolog 1 RAD51 0.007
5649 Potassium-transporting ATPase B chain kdpB 0.007
3794 Osmolarity sensor protein envZ envZ 0.007
5644 Sensor protein phoQ phoQ 0.007
5643 General secretion pathway protein E epsE 0.007
5645 DNA topoisomerase 4 subunit B parE 0.007
6227 DNA topoisomerase 4 subunit B parE 0.007
5642 Chaperone clpB clpB 0.007
248 Pyrroline-5-carboxylate reductase 1 PYCR1 0.007
802 Pyrroline-5-carboxylate reductase 2 PYCR2 0.007
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0068
897 Glutathione S-transferase kappa 1 GSTK1 0.0066
594 Thyroxine-binding globulin SERPINA7 0.0066
2251 Thymidylate kinase tmk 0.0066
2254 Thymidylate kinase DTYMK 0.0066
3522 Thymidylate kinase tmk 0.0066
898 Glutathione S-transferase A3 GSTA3 0.0065
3319 Hydroxyacylglutathione hydrolase HAGH 0.0065
4751 Mitogen-activated protein kinase 12 MAPK12 0.0064
909 Maleylacetoacetate isomerase GSTZ1 0.0063
2852 DNA mismatch repair protein mutL mutL 0.0062
2397 Dihydroxyacetone kinase dhaK 0.0061
2867 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE 0.0061
6433 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 PFKFB4 0.0061
3822 Actin, alpha skeletal muscle ACTA1 0.0061
758 Thyroid hormone receptor alpha THRA 0.0061
252 Tryptophanyl-tRNA synthetase, cytoplasmic WARS 0.0059
765 Indoleamine 2,3-dioxygenase IDO1 0.0059
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0058
2165 Glutathione S-transferase Mu 2 GSTM2 0.0058
4041 Microsomal glutathione S-transferase 2 MGST2 0.0058
2299 UDP-N-acetylmuramate--L-alanine ligase murC 0.0057
2452 Tryptophanyl-tRNA synthetase trpS 0.0056
3231 Death-associated protein kinase 1 DAPK1 0.0056
1721 Glycogen synthase kinase-3 beta GSK3B 0.0056
134 Tryptophan 5-hydroxylase 1 TPH1 0.0055
901 Glutathione S-transferase Mu 4 GSTM4 0.0054
887 DNA gyrase subunit B gyrB 0.0054
4150 DNA gyrase subunit B gyrB 0.0054
6225 DNA gyrase subunit B gyrB 0.0054
346 Thyroid hormone receptor beta-1 THRB 0.0054
6012 Tryptophan 2,3-dioxygenase TDO2 0.0053
936 Ephrin type-A receptor 2 EPHA2 0.0053
958 Insulin-like growth factor 1 receptor IGF1R 0.0053
374 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NDUFB1 0.0053
99 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NDUFS5 0.0053
247 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUFA1 0.0053
343 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NDUFC1 0.0053
582 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NDUFA13 0.0053
190 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 NDUFA4 0.0053
755 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NDUFA3 0.0053
353 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 NDUFA4L2 0.0053
405 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NDUFA8 0.0053
313 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NDUFB3 0.0053
607 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NDUFA2 0.0053
475 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NDUFB2 0.0053
30 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NDUFV3 0.0053
446 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NDUFA7 0.0053
525 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NDUFA5 0.0053
219 NADH-ubiquinone oxidoreductase chain 3 MT-ND3 0.0053
104 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NDUFS6 0.0053
236 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NDUFA6 0.0053
417 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NDUFB6 0.0053
324 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NDUFB4 0.0053
50 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating NSDHL 0.0053
568 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NDUFB7 0.0053
598 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NDUFA11 0.0053
829 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NDUFA12 0.0053
602 Acyl carrier protein, mitochondrial NDUFAB1 0.0053
272 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NDUFB10 0.0053
384 NADH-ubiquinone oxidoreductase chain 6 MT-ND6 0.0053
555 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 0.0053
656 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 0.0053
729 GDP-L-fucose synthetase TSTA3 0.0053
3463 GDP-L-fucose synthetase fcl 0.0053
746 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NDUFB8 0.0053
326 L-lactate dehydrogenase A-like 6A LDHAL6A 0.0053
270 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NDUFB5 0.0053
141 3-hydroxyisobutyrate dehydrogenase, mitochondrial HIBADH 0.0053
196 D-beta-hydroxybutyrate dehydrogenase, mitochondrial BDH1 0.0053
721 NADH-ubiquinone oxidoreductase chain 2 MT-ND2 0.0053
231 Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic GPD1 0.0053
539 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NDUFV1 0.0053
107 C-4 methylsterol oxidase SC4MOL 0.0053
41 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NDUFS8 0.0053
216 Aldehyde dehydrogenase 3B2 ALDH3B2 0.0053
616 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial IDH3B 0.0053
671 Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial PDHA2 0.0053
628 Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial PDHA1 0.0053
300 NADH-ubiquinone oxidoreductase chain 4L MT-ND4L 0.0053
152 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NDUFV2 0.0053
496 Aldehyde dehydrogenase 3B1 ALDH3B1 0.0053
609 15-hydroxyprostaglandin dehydrogenase [NAD+] HPGD 0.0053
711 UDP-glucose 6-dehydrogenase UGDH 0.0053
3672 UDP-glucose 6-dehydrogenase hasB 0.0053
149 Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 0.0053
531 Aldehyde dehydrogenase X, mitochondrial ALDH1B1 0.0053
258 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial ALDH6A1 0.0053
372 Estradiol 17-beta-dehydrogenase 3 HSD17B3 0.0053
644 Heme oxygenase 2 HMOX2 0.0053
4982 Heme oxygenase 2 pbsA2 0.0053
271 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial ALDH4A1 0.0053
487 Aldo-keto reductase family 1 member C4 AKR1C4 0.0053
167 L-lactate dehydrogenase C chain LDHC 0.0053
637 NADH-ubiquinone oxidoreductase chain 5 MT-ND5 0.0053
206 3-keto-steroid reductase HSD17B7 0.0053
91 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NDUFA10 0.0053
14 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial IDH3A 0.0053
335 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NDUFA9 0.0053
112 L-lactate dehydrogenase A-like 6B LDHAL6B 0.0053
9 Estradiol 17-beta-dehydrogenase 2 HSD17B2 0.0053
848 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial IDH3G 0.0053
145 Corticosteroid 11-beta-dehydrogenase isozyme 2 HSD11B2 0.0053
288 Trifunctional enzyme subunit alpha, mitochondrial HADHA 0.0053
393 GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase H6PD 0.0053
608 NADH-ubiquinone oxidoreductase chain 4 MT-ND4 0.0053
34 7-dehydrocholesterol reductase DHCR7 0.0053
662 Fatty aldehyde dehydrogenase ALDH3A2 0.0053
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.0052
3726 D-3-phosphoglycerate dehydrogenase serA 0.0052
4291 D-3-phosphoglycerate dehydrogenase serA 0.0052
643 Peroxisomal bifunctional enzyme EHHADH 0.0052
548 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NDUFS1 0.0052
816 Biliverdin reductase A BLVRA 0.0052
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0052
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0052
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0052
834 Arginase-2, mitochondrial ARG2 0.0051
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0051
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.005
577 Argininosuccinate lyase ASL 0.0049
1313 Lactoylglutathione lyase GLO1 0.0049
480 Methionine-R-sulfoxide reductase B2 MSRB2 0.0048
317 Methionine-R-sulfoxide reductase SEPX1 0.0048
3996 Betaine--homocysteine S-methyltransferase 2 BHMT2 0.0048
3921 Methionine adenosyltransferase 2 subunit beta MAT2B 0.0048
3995 Methionyl-tRNA synthetase, mitochondrial MARS2 0.0048
600 Methionyl-tRNA synthetase, cytoplasmic MARS 0.0048
4031 Glutathione S-transferase A1 GSTA1 0.0047
4192 DNA topoisomerase 2-beta TOP2B 0.0046
6141 Sodium/bile acid cotransporter SLC10A1 0.0046
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0045
908 Glutathione S-transferase theta-1 GSTT1 0.0045
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0045
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.0044
646 Malate dehydrogenase, cytoplasmic MDH1 0.0044
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0044
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0044
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.0044
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.0043
666 NADP-dependent malic enzyme ME1 0.0043
363 NADP-dependent malic enzyme, mitochondrial ME3 0.0043
7 Nitric oxide synthase, inducible NOS2 0.0043
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0043
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0043
291 Nitric-oxide synthase, endothelial NOS3 0.0042
328 Sorbitol dehydrogenase SORD 0.0042
597 Dihydropteridine reductase QDPR 0.0042
396 Alcohol dehydrogenase 4 ADH4 0.0042
896 Glutathione S-transferase Mu 1 GSTM1 0.0042
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0042
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0042
397 Monocarboxylate transporter 3 SLC16A8 0.0041
218 Monocarboxylate transporter 5 SLC16A4 0.0041
857 Malate dehydrogenase, mitochondrial MDH2 0.0041
195 Monocarboxylate transporter 7 SLC16A6 0.0041
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0041
429 Monocarboxylate transporter 6 SLC16A5 0.0041
6026 Alcohol dehydrogenase 6 ADH6 0.0041
296 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial MTHFD2 0.0041
4943 Cytochrome c6 petJ 0.0041
4934 Cytochrome c-551 nirM 0.0041
5218 Cytochrome c-551 nirM 0.0041
4936 Cytochrome c2 iso-2 Not Available 0.0041
4981 Iron-starvation protein PigA pigA 0.0041
4994 Hemoglobin-like protein HbO glbO 0.0041
4915 Cytochrome c-550 psbV 0.0041
4959 Cytochrome c-550 psbV 0.0041
5216 Cytochrome c-550 psbV 0.0041
4925 Cytochrome c-type protein SHP shp 0.0041
4998 Hemoglobin-like protein yjbI yjbI 0.0041
4905 Cytochrome c2 Not Available 0.0041
4939 Cytochrome c2 cycA 0.0041
4964 Cytochrome c2 cycA 0.0041
4979 Cytochrome c2 cycA 0.0041
6673 Cytochrome c2 cycA 0.0041
4909 CooA protein cooA 0.0041
4947 Bacterial hemoglobin vhb 0.0041
4975 Cytochrome c-556 RPA3973 0.0041
4984 Neuroglobin NGB 0.0041
3116 Bacterioferritin bfr 0.0041
4906 Bacterioferritin bfr 0.0041
4965 Bacterioferritin bfr 0.0041
4954 Soluble cytochrome b558 Not Available 0.0041
4961 Hemophore HasA hasA 0.0041
4910 Cytoglobin CYGB 0.0041
4976 Apocytochrome f petA 0.0041
6407 Apocytochrome f petA 0.0041
4916 Cyanoglobin glbN 0.0041
5000 HemO hemO 0.0041
4935 Cytochrome c-554 cycA1 0.0041
4942 Diheme cytochrome c napB napB 0.0041
4931 Cytochrome P450 167A1 CYP167A1 0.0041
4922 Cytochrome c, putative SO_4144 0.0041
4971 Nonaheme cytochrome c hmcA 0.0041
4989 Cytochrome c551 peroxidase ccp 0.0041
5222 Cytochrome c551 peroxidase ccpA 0.0041
4904 Cytochrome c family protein GSU1996 0.0041
4907 Cytochrome c-L moxG 0.0041
6865 Cytochrome c-L moxG 0.0041
4999 Cytochrome P450 165B3 CYP165B3 0.0041
4972 P450cin cinA 0.0041
4764 Cytochrome P450 165C4 CYP165C4 0.0041
4960 Putative cytochrome P450-family protein SCO7417 0.0041
4926 Heme-based aerotactic transducer hemAT hemAT 0.0041
4952 Catalase/peroxidase katA 0.0041
3093 Catalase HPII katE 0.0041
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0041
4937 Cytochrome oxidase subunit II rcoxA 0.0041
4993 Hydroxylamine oxidoreductase hao1 0.0041
4903 Methyl-accepting chemotaxis protein Tar4 0.0041
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0041
191 Peptide methionine sulfoxide reductase MSRA 0.0041
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.004
587 Serum albumin ALB 0.004
373 Transthyretin TTR 0.004
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.004
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.004
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.004
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.004
627 11-cis retinol dehydrogenase RDH5 0.004
640 Aldehyde dehydrogenase 1A3 ALDH1A3 0.004
1836 Mitogen-activated protein kinase 10 MAPK10 0.004
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.004
11 NAD(P) transhydrogenase, mitochondrial NNT 0.0039
941 Betaine--homocysteine S-methyltransferase 1 BHMT 0.0039
12 Alcohol dehydrogenase class 3 ADH5 0.0039
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0039
77 L-lactate dehydrogenase B chain LDHB 0.0038
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0038
5314 UPF0079 ATP-binding protein HI0065 HI_0065 0.0038
5293 Shikimate kinase 2 aroL 0.0038
5288 Shikimate kinase aroK 0.0038
5304 UPF0166 protein TM_0021 TM_0021 0.0038
5287 Signaling protein Not Available 0.0038
5292 Putative partitioning protein TT_C1605 0.0038
5266 Activator of hgdC 0.0038
5259 Transcriptional regulator ntrC1 0.0038
6699 Transcriptional regulator Cgl2612 0.0038
5270 ATP-dependent Clp protease ATP-binding subunit clpX clpX 0.0038
3199 Phosphopantetheine adenylyltransferase coaD 0.0038
3543 Phosphopantetheine adenylyltransferase coaD 0.0038
3567 Phosphopantetheine adenylyltransferase coaD 0.0038
5289 Phosphopantetheine adenylyltransferase coaD 0.0038
2874 Nitrogenase iron protein 1 nifH1 0.0038
4346 Polynucleotide kinase pseT 0.0038
5283 D-alanine--D-alanine ligase B ddlB 0.0038
5281 Plasmid segregation protein parM parM 0.0038
5305 Phosphoribosylaminoimidazole carboxylase ATPase subunit purK 0.0038
5275 Multidrug resistance ABC transporter ATP-binding and permease protein lmrA 0.0038
5315 Chaperone protein htpG htpG 0.0038
5290 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0038
5638 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0038
5291 Glycogen synthase 1 glgA1 0.0038
3777 ATP-dependent Clp protease ATP-binding subunit clpA clpA 0.0038
5264 DNA replication protein REP 0.0038
4794 Phosphoenolpyruvate carboxykinase [ATP] pckA 0.0038
5308 Preprotein translocase secA 1 subunit secA1 0.0038
5285 Kinesin heavy chain KIF5B 0.0038
1549 Heat shock 70 kDa protein 1 HSPA1A 0.0038
5299 D-alanine--D-alanine ligase ddl 0.0038
6598 D-alanine--D-alanine ligase ddl 0.0038
5284 Large T antigen Not Available 0.0038
5276 Chromosomal replication initiator protein dnaA dnaA 0.0038
5277 Preprotein translocase subunit secA secA 0.0038
569 Retinal dehydrogenase 2 ALDH1A2 0.0038
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0038
2236 Casein kinase II subunit alpha CSNK2A1 0.0037
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0037
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0037
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0037
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0037
13 Aminomethyltransferase, mitochondrial AMT 0.0037
6136 Multidrug resistance-associated protein 5 ABCC5 0.0036
74 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial DLAT 0.0036
473 L-lactate dehydrogenase A chain LDHA 0.0036
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0036
52 Pyruvate kinase isozymes R/L PKLR 0.0035
57 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I HSD3B1 0.0035
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0035
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0035
611 Retinal dehydrogenase 1 ALDH1A1 0.0035
4085 Peptidyl-prolyl cis-trans isomerase C PPIC 0.0035
4088 Probable prolyl-tRNA synthetase, mitochondrial PARS2 0.0035
4083 Peptidyl-prolyl cis-trans isomerase H PPIH 0.0035
4087 Pyrroline 5-carboxylate reductase isoform P5CR2 0.0035
4090 Chromosome 14 open reading frame 149 C14orf149 0.0035
4082 Proline oxidase, mitochondrial PRODH 0.0035
797 Sodium-dependent proline transporter SLC6A7 0.0035
4086 Peptidyl-prolyl cis-trans isomerase G PPIG 0.0035
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0035
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0034
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0034
771 Pyruvate carboxylase, mitochondrial PC 0.0034
279 Tyrosinase TYR 0.0034
1517 Beta-3 adrenergic receptor ADRB3 0.0034
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0034
6142 Solute carrier family 22 member 8 SLC22A8 0.0033
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0033
840 Methionine synthase reductase, mitochondrial MTRR 0.0033
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0032
251 Alcohol dehydrogenase 1A ADH1A 0.0032
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0032
163 D(1B) dopamine receptor DRD5 0.0032
98 Pyruvate kinase isozymes M1/M2 PKM2 0.0032
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0031
3426 Glutamine synthetase glnA 0.0031
3987 Glutamine synthetase GLUL 0.0031
3175 Glutamate--cysteine ligase gshA 0.0031
4289 Cytochrome P450 TT_P0059 0.0031
6262 Cytochrome P450 staP 0.0031
4992 Cytochrome c peroxidase Not Available 0.0031
809 Methionine synthase MTR 0.0031
2935 Methionine synthase metH 0.0031
4920 Peroxidase/catalase katG 0.0031
3570 Cytochrome P450 152A1 cypC 0.003
5295 2-keto-3-deoxy-gluconate kinase TT_P0036 0.003
432 D(4) dopamine receptor DRD4 0.003
3470 Hypothetical protein MG245 homolog MPN_348 0.003
2164 Multidrug resistance-associated protein 4 ABCC4 0.003
4990 PpcA ppcA 0.003
4923 Cytochrome c3 DvMF_2499 0.003
4945 Cytochrome c3 Not Available 0.003
4949 Cytochrome c3 DVU_3171 0.003
4968 Cytochrome c3 cytc3 0.003
4997 Cytochrome c3 SO_2727 0.003
5219 Cytochrome c3 cyd 0.003
4948 Cytochrome c-553 Not Available 0.003
4902 Nine-heme cytochrome c Ddes_2038 0.003
3189 High-molecular-weight cytochrome c hmcA 0.003
4813 Heme oxygenase hmuO 0.003
5769 Heme oxygenase Not Available 0.003
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.003
2230 Catalase CAT 0.003
3249 Catalase katA 0.003
3625 Catalase katA 0.003
4539 Catalase katA 0.003
4941 Catalase katB 0.003
4988 Sulfite oxidase, mitochondrial SUOX 0.003
2751 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.003
4755 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.003
5189 Trimethylamine dehydrogenase tmd 0.003
654 Flavin reductase BLVRB 0.003
4106 Guanylate kinase GUK1 0.003
4516 Guanylate kinase gmk 0.003
2270 Dephospho-CoA kinase coaE 0.003
2284 Adenylate kinase adk 0.003
2296 Adenylate kinase adk 0.003
2311 Adenylate kinase adk 0.003
2312 Adenylate kinase Not Available 0.003
2119 Cytochrome b5 CYB5A 0.003
2915 Sensor protein fixL fixL 0.003
4944 Sensor protein fixL fixL 0.003
6277 Heat shock cognate 71 kDa protein HSPA8 0.003
4837 Cag-alfa cag-alfa 0.003
4839 DNA polymerase III subunit tau dnaX 0.003
4774 NTPase P4 Not Available 0.003
4838 PMS1 protein homolog 2 PMS2 0.003
3375 Acidic cytochrome c3 Not Available 0.003
4385 Cytochrome c' Not Available 0.003
4967 Cytochrome c' cycA 0.003
5038 Cytochrome c' Not Available 0.003
5223 Cytochrome c' cycP 0.003
4084 Peptidyl-prolyl cis-trans isomerase B PPIB 0.003
638 D(3) dopamine receptor DRD3 0.0029
4000 Prolyl 4-hydroxylase subunit alpha-2 P4HA2 0.0029
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0029
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0029
1008 CTP synthase 1 CTPS 0.0029
3988 Protein-glutamine gamma-glutamyltransferase K TGM1 0.0029
3985 Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2 GFPT2 0.0029
3990 Protein-glutamine gamma-glutamyltransferase 4 TGM4 0.0029
3986 Protein-glutamine gamma-glutamyltransferase 6 TGM6 0.0029
3992 Protein-glutamine gamma-glutamyltransferase Z TGM7 0.0029
3983 Protein-glutamine gamma-glutamyltransferase 5 TGM5 0.0029
3989 Glutaminyl-tRNA synthetase QARS 0.0029
2683 Mono-ADP-ribosyltransferase C3 C3 0.0029
340 Apoptotic protease-activating factor 1 APAF1 0.0028
862 Multidrug resistance-associated protein 1 ABCC1 0.0028
444 Alcohol dehydrogenase 1B ADH1B 0.0028
5300 Antigen peptide transporter 1 TAP1 0.0028
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0027
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0027
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0027
380 Cytochrome P450 17A1 CYP17A1 0.0027
2617 Nitric oxide synthase oxygenase nos 0.0027
2701 Nitric oxide synthase oxygenase nos 0.0027
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0027
2554 Peptidyl-prolyl cis-trans isomerase, mitochondrial PPIF 0.0027
5271 Focal adhesion kinase 1 PTK2 0.0027
2390 Nonsecretory ribonuclease RNASE2 0.0027
2922 Glycerol kinase glpK 0.0027
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0026
518 Peroxidase/catalase T katG 0.0026
3670 Soluble cytochrome b562 precursor cybC 0.0026
2795 Methionine aminopeptidase 2 METAP2 0.0026
23 D(1A) dopamine receptor DRD1 0.0026
3291 Cytochrome c-552 cycA 0.0026
4927 Cytochrome c-552 nrfA 0.0026
4938 Cytochrome c-552 cycA 0.0026
4953 Cytochrome c-552 nrfA 0.0026
5217 Cytochrome c-552 cycM 0.0026
3102 Flavohemoprotein hmp 0.0026
4969 Flavohemoprotein hmp 0.0026
468 Cytochrome P450 4A11 CYP4A11 0.0026
4386 Hemoglobin-like protein HbN glbN 0.0026
3411 Cytochrome P450 121 cyp121 0.0026
2282 Protein recA recA 0.0026
2315 Protein recA recA 0.0026
2332 Protein recA recA 0.0026
5263 Protein recA recA 0.0026
3917 Methylenetetrahydrofolate reductase MTHFR 0.0026
789 Alpha-1D adrenergic receptor ADRA1D 0.0026
408 Riboflavin kinase RFK 0.0026
3949 Prolyl 3-hydroxylase 2 LEPREL1 0.0025
3945 Prolyl 3-hydroxylase 1 LEPRE1 0.0025
3951 Prolyl 3-hydroxylase 3 LEPREL2 0.0025
788 Creatine kinase M-type CKM 0.0025
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0025
6020 Aldehyde oxidase AOX1 0.0025
378 Alpha-2C adrenergic receptor ADRA2C 0.0025
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0025
6857 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial PDK2 0.0025
1588 Multidrug resistance protein 1 ABCB1 0.0025
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0025
3669 Ribokinase rbsK 0.0025
831 D(2) dopamine receptor DRD2 0.0024
1596 Protein-glutamine gamma-glutamyltransferase 2 TGM2 0.0024
629 Alpha-2B adrenergic receptor ADRA2B 0.0024
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0024
118 Organic cation/carnitine transporter 2 SLC22A5 0.0024
605 Fumarate reductase flavoprotein subunit frdA 0.0024
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0024
3673 Fumarate reductase flavoprotein subunit fccA 0.0024
4912 Fumarate reductase flavoprotein subunit ifcA 0.0024
6549 Fumarate reductase flavoprotein subunit frdA 0.0024
3221 Cytochrome c4 cc4 0.0024
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0024
193 Beta-1 adrenergic receptor ADRB1 0.0024
3127 Nitrite reductase nirS 0.0024
3284 Nitrite reductase nirS 0.0024
2972 6-deoxyerythronolide B hydroxylase eryF 0.0024
6 Coagulation factor XIII A chain F13A1 0.0024
67 Prolyl 4-hydroxylase subunit alpha-1 P4HA1 0.0023
517 Alcohol dehydrogenase 1C ADH1C 0.0023
6390 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 ATP2A1 0.0023
766 Beta-2 adrenergic receptor ADRB2 0.0023
4924 Cytochrome P450 2C8 CYP2C8 0.0023
2334 Dethiobiotin synthetase bioD 0.0023
6555 Dethiobiotin synthetase bioD 0.0023
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0023
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0023
632 Alpha-1B adrenergic receptor ADRA1B 0.0023
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0023
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0023
413 Amidophosphoribosyltransferase PPAT 0.0023
2515 Amidophosphoribosyltransferase purF 0.0023
3714 Amidophosphoribosyltransferase purF 0.0023
4608 Putative cytochrome P450 SCO1207 0.0022
4963 Putative cytochrome P450 SCO2884 0.0022
6254 Putative cytochrome P450 SCO6998 0.0022
2697 Uridine-cytidine kinase 2 UCK2 0.0022
3947 Xanthine dehydrogenase/oxidase XDH 0.0022
318 Alpha-2A adrenergic receptor ADRA2A 0.0022
61 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0021
2644 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0021
2710 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0021
822 Aldose reductase AKR1B1 0.0021
48 Pyridoxal kinase PDXK 0.0021
365 Dihydrofolate reductase DHFR 0.0021
2381 Dihydrofolate reductase DFR1 0.0021
2833 Dihydrofolate reductase Not Available 0.0021
2931 Dihydrofolate reductase folA 0.0021
3544 Dihydrofolate reductase folA 0.0021
3682 Dihydrofolate reductase folA 0.0021
6642 Dihydrofolate reductase folA 0.0021
6756 Dihydrofolate reductase dfrA 0.0021
2511 MAP kinase-activated protein kinase 2 MAPKAPK2 0.0021
2317 UDP-N-acetylmuramoylalanine--D-glutamate ligase murD 0.0021
1507 Cytochrome c CYCS 0.0021
702 UMP-CMP kinase CMPK1 0.0021
2091 Endoplasmin HSP90B1 0.002
260 Cytochrome P450 51 ERG11 0.002
761 Cytochrome P450 51 ERG11 0.002
3163 Cytochrome P450 51 cyp51 0.002
556 Alpha-1A adrenergic receptor ADRA1A 0.002
6395 Myosin-14 MYH14 0.002
2339 Protein-glutamine gamma-glutamyltransferase E TGM3 0.002
693 Hemoglobin subunit beta HBB 0.002
1422 Serine/threonine-protein kinase 6 AURKA 0.0019
6268 Hydroxyacid oxidase 1 HAO1 0.0019
3379 Kinesin-like protein KIF11 KIF11 0.0019
3456 Heat shock protein HSP 90-beta HSP90AB1 0.0019
504 Mast/stem cell growth factor receptor KIT 0.0019
4119 Cytochrome P450 2D6 CYP2D6 0.0018
509 Thymidine kinase TK 0.0018
570 Thymidine kinase TK 0.0018
2559 Thymidine kinase TK 0.0018
3430 Thymidine kinase tdk 0.0018
3518 Thymidine kinase TK 0.0018
5301 Thymidine kinase tdk 0.0018
5771 Thymidine kinase ORF36 0.0018
7009 Thymidine kinase ORF36 0.0018
5294 Nucleoside diphosphate kinase A NME1 0.0017
4773 Deoxycytidine kinase DCK 0.0017
2298 Cytochrome P450-cam camC 0.0016
76 Nitric-oxide synthase, brain NOS1 0.0015
6106 Cytochrome P450 2C18 CYP2C18 0.0015
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0014
290 Prostaglandin G/H synthase 2 PTGS2 0.0012
20 Prostaglandin G/H synthase 1 PTGS1 0.0012
6030 Cytochrome P450 2B6 CYP2B6 0.0011
4757 Cytochrome P450 2C9 CYP2C9 0.0009
4512 Cytochrome P450 3A4 CYP3A4 0.0008
↑