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2-dehydro-3-deoxyphosphooctonate aldolase


Partner ID 2542
Name 2-dehydro-3-deoxyphosphooctonate aldolase
Synonyms 4100
Gene name kdsA
General function Cell wall/membrane/envelope biogenesis
Specific function Phosphoenolpyruvate + D-arabinose 5-phosphate + H(2)O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate
Gene sequence + ...

ATGAAACAAAAAGTGGTTAGCATTGGCGACATCAACGTAGCAAATGACCTGCCGTTCGTACTGTTTGGCGGTATGAACGTGCTGGAATCTCGCGATCTGGCGATGCGCATTTGCGAGCACTACGTAACTGTGACCCAGAAACTGGGTATCCCTTACGTGTTCAAAGCCTCTTTTGACAAAGCCAACCGCTCCTCCATCCACTCTTATCGTGGACCGGGCCTGGAAGAAGGGATGAAAATCTTCCAGGAGTTGAAGCAGACTTTTGGCGTGAAAATTATCACCGACGTTCACGAACCAAGTCAGGCACAGCCCGTTGCTGATGTCGTGGATGTGATTCAGTTGCCGGCGTTTCTTGCTCGCCAGACTGACCTGGTTGAAGCCATGGCGAAAACCGGTGCGGTAATTAACGTCAAGAAACCACAGTTTGTCAGCCCGGGACAGATGGGTAATATCGTTGATAAATTCAAAGAAGGCGGCAACGAAAAAGTGATTCTTTGCGATCGTGGTGCTAACTTCGGCTATGACAACCTGGTTGTCGATATGCTGGGCTTCAGCATTATGAAGAAAGTGTCTGGTAACTCGCCGGTGATTTTCGACGTGACCCACGCACTGCAATGCCGCGATCCGTTTGGCGCAGCTTCCGGTGGTCGTCGTGCTCAGGTGGCTGAGCTGGCACGAGCCGGTATGGCGGTAGGTCTGGCGGGGCTGTTTATTGAAGCGCATCCGGATCCGGAACATGCGAAATGTGATGGTCCATCCGCGCTGCCGCTGGCTAAACTGGAACCGTTCCTCAAGCAGATGAAAGCGATTGATGATCTGGTGAAAGGTTTCGAAGAACTGGATACCAGCAAGTAA
Protein sequence + ...

MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGNEKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRRAQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKGFEELDTSK
GO Classification
component
cell
intracellular
cytoplasm
function
transferase activity, transferring alkyl or aryl (other than methyl) groups
3-deoxy-8-phosphooctulonate synthase activity
catalytic activity
transferase activity
process
physiological process
metabolism
biosynthesis
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB01819 Phosphoenolpyruvate
DB02433 {[(2,2-Dihydroxy-Ethyl)-(2,3,4,5-Tetrahydroxy-6-Phosphonooxy-Hexyl)-Amino]-Methyl}-Phosphonic Acid
DB03113 3-Fluoro-2-(Phosphonooxy)Propanoic Acid
DB03936 1-Deoxy-Ribofuranose-5'-Phosphate

Associated as Prediction

Id Name
DB00119 Pyruvic acid
DB00695 Furosemide
DB00770 Alprostadil
DB00917 Dinoprostone
DB01088 Iloprost
DB01160 Dinoprost Tromethamine
DB01174 Phenobarbital
DB01709 2-Phosphoglyceric Acid
DB01779 Glycerol-2-Phosphate
DB01819 Phosphoenolpyruvate
DB02007 Alpha-D-Glucose-6-Phosphate
DB02008 1-(2-Fluorobenzyl)-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine
DB02053 Ribose-5-Phosphate
DB02059 Adenosine-5-Diphosphoribose
DB02076 6-Phosphogluconic Acid
DB02093 5-Phospho-D-Arabinohydroxamic Acid
DB02263 Glyceraldehyde-3-Phosphate
DB02433 {[(2,2-Dihydroxy-Ethyl)-(2,3,4,5-Tetrahydroxy-6-Phosphonooxy-Hexyl)-Amino]-Methyl}-Phosphonic Acid
DB02515 3-Phosphoglycerol
DB02548 Sorbitol 6-phosphate
DB02726 2-Phosphoglycolic Acid
DB02787 N-Acetylmannosaminitol
DB02951 3-Hydroxypyruvic Acid
DB02992 1-Deoxy-6-O-Phosphono-1-[(Phosphonomethyl)Amino]-L-Threo-Hexitol
DB03042 5-Phosphoarabinonic Acid
DB03113 3-Fluoro-2-(Phosphonooxy)Propanoic Acid
DB03248 2-(Phosphonooxy)Butanoic Acid
DB03267 1-Allyl-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine
DB03499 Malate Ion
DB03581 Glucose-6-Phosphate
DB03725 Phosphomethylphosphonic Acid-Guanylate Ester
DB03745 Arabinose-5-Phosphate
DB03936 1-Deoxy-Ribofuranose-5'-Phosphate
DB03937 Erythose-4-Phosphate
DB04398 Lactic Acid
DB04493 Fructose-6-Phosphate
DB04510 3-Phosphoglyceric Acid
DB04551 Fructose-1,6-Diphosphate
DB04557 Arachidonic Acid
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