DT-Web

DB04510 - 3-Phosphoglyceric Acid


Identification
Name 3-Phosphoglyceric Acid
Accession Number DB04510 (EXPT00187)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 186.0572
Groups experimental
Monoisotopic Weight 185.99293909
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Phosphoglycerate kinase 1
Name Phosphoglycerate kinase 1
Gene Name PGK1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Bifunctional PGK/TIM [Includes: Phosphoglycerate kinase
Name Bifunctional PGK/TIM [Includes: Phosphoglycerate kinase
Gene Name pgk/tpi
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.905
Triosephosphate isomerase
Name Triosephosphate isomerase
Gene Name TPI
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.5891
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Name 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Gene Name gpmI
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.2109
Phosphoglycerate mutase 2
Name Phosphoglycerate mutase 2
Gene Name PGAM2
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Triosephosphate isomerase
Name Triosephosphate isomerase
Gene Name TPI1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.5891

Predictions


Id Partner name Gene Name Score
3417 Triosephosphate isomerase tpiA 1.5891
3443 Triosephosphate isomerase tpiA 1.5891
2310 2-dehydro-3-deoxyphosphooctonate aldolase kdsA 0.3045
2542 2-dehydro-3-deoxyphosphooctonate aldolase kdsA 0.3045
3000 N-acetylneuraminate lyase nanA 0.2031
2803 Pyridoxine 5'-phosphate synthase pdxJ 0.1088
2914 Triosephosphate isomerase, glycosomal Not Available 0.103
3705 L-fuculose phosphate aldolase fucA 0.1016
1750 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 PFKFB1 0.0981
3467 Methylglyoxal synthase mgsA 0.0779
3069 Fructose-bisphosphate aldolase A ALDOA 0.059
2904 Phosphatase yniC yniC 0.0582
896 Glutathione S-transferase Mu 1 GSTM1 0.0565
3192 Glucosamine-6-phosphate deaminase 1 nagB 0.0506
3309 6-phosphofructokinase pfkA 0.0506
3676 Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive aroG 0.0506
52 Pyruvate kinase isozymes R/L PKLR 0.0414
3419 Rhamnulose-1-phosphate aldolase rhaD 0.0389
3727 Tagatose-1,6-bisphosphate aldolase agaY kbaY 0.0389
3693 Fructose-bisphosphate aldolase class 2 fbaA 0.0389
98 Pyruvate kinase isozymes M1/M2 PKM2 0.0383
2392 Biphenyl-2,3-diol 1,2-dioxygenase bphC 0.0326
3032 Biphenyl-2,3-diol 1,2-dioxygenase bphC 0.0326
2795 Methionine aminopeptidase 2 METAP2 0.0262
5682 Ribonuclease pancreatic RNASE1 0.0233
465 Calmodulin CALM1 0.0187
5670 Organic hydroperoxide resistance protein ohr 0.0106
5669 50S ribosomal protein L27 rpmA 0.0106
5675 Chaperone protein torD torD 0.0106
5672 Molybdenum cofactor biosynthesis protein A moaA 0.0106
5410 Unsaturated glucuronyl hydrolase ugl 0.0106
5676 Axin-1 AXIN1 0.0106
5673 C protein alpha-antigen bca 0.0106
3317 Holo-[acyl-carrier-protein] synthase acpS 0.0092
4381 Holo-[acyl-carrier-protein] synthase acpS 0.0092
2636 Shikimate dehydrogenase aroE 0.0092
3515 Shikimate dehydrogenase aroE 0.0092
3125 Protease synthase and sporulation negative regulatory protein PAI 1 paiA 0.0092
5599 3-carboxy-cis,cis-muconate cycloisomerase pcaB 0.0092
2280 Listeriolysin regulatory protein prfA 0.0085
6579 Calcium/calmodulin-dependent protein kinase type II alpha chain CAMK2A 0.0085
4811 Amylosucrase ams 0.0085
3191 Histidinol dehydrogenase hisD 0.008
191 Peptide methionine sulfoxide reductase MSRA 0.0076
4084 Peptidyl-prolyl cis-trans isomerase B PPIB 0.0075
909 Maleylacetoacetate isomerase GSTZ1 0.0075
611 Retinal dehydrogenase 1 ALDH1A1 0.0058
24 Thymidylate synthase TMP1 0.0057
359 Thymidylate synthase TYMS 0.0057
2626 Thymidylate synthase thyA 0.0057
2729 Thymidylate synthase thyA 0.0057
5352 Thymidylate synthase THYA 0.0057
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0049
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0049
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