DT-Web

DB03884 - 3-Phenylpyruvic Acid


Identification
Name 3-Phenylpyruvic Acid
Accession Number DB03884 (EXPT02649)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 164.158
Groups experimental
Monoisotopic Weight 164.047344122
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


L-phenylalanine dehydrogenase
Name L-phenylalanine dehydrogenase
Gene Name pdh
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.0246
Hydroxyacid oxidase 1
Name Hydroxyacid oxidase 1
Gene Name HAO1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.8918
Indole-3-pyruvate decarboxylase
Name Indole-3-pyruvate decarboxylase
Gene Name ipdC
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.9619
Putative uncharacterized protein
Name Putative uncharacterized protein
Gene Name CV_3270
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.1237
Bacilysin biosynthesis protein bacB
Name Bacilysin biosynthesis protein bacB
Gene Name bacB
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.1234
Probable chorismate mutase
Name Probable chorismate mutase
Gene Name pheA
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.1235

Transporters


Monocarboxylate transporter 4
Name Monocarboxylate transporter 4
Gene Name SLC16A3
Actions substrate
References
  • Manning Fox JE, Meredith D, Halestrap AP: Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle. J Physiol. 2000 Dec 1;529 Pt 2:285-93. - Pubmed
DTHybrid score 0.8825

Predictions


Id Partner name Gene Name Score
5607 Indole-3-pyruvate decarboxylase ipdC 1.9619
6508 Putative uncharacterized protein srtB 1.1237
6543 Putative uncharacterized protein tcp14 1.1237
6615 Putative uncharacterized protein MT0785 1.1237
6623 Putative uncharacterized protein Not Available 1.1237
6806 Putative uncharacterized protein AGR_C_2535 1.1237
6813 Putative uncharacterized protein SAV4671 1.1237
6815 Putative uncharacterized protein AFE_1514 1.1237
6819 Putative uncharacterized protein RUMGNA_03254 1.1237
5180 L(+)-mandelate dehydrogenase mdlB 0.2088
489 Monocarboxylate transporter 2 SLC16A7 0.1573
738 Monocarboxylate transporter 1 SLC16A1 0.1333
6337 NHP2-like protein 1 NHP2L1 0.0491
6327 60S ribosomal protein L23 RPL23 0.0491
6336 60S ribosomal protein L11 RPL11 0.0491
6329 60S ribosomal protein L19 RPL19 0.0491
6328 60S ribosomal protein L15 RPL15 0.0491
6325 60S ribosomal protein L10-like RPL10L 0.0491
6333 60S ribosomal protein L8 RPL8 0.0491
6332 60S ribosomal protein L26-like 1 RPL26L1 0.0491
6330 60S ribosomal protein L23a RPL23A 0.0491
6331 Probable ribosome biogenesis protein RLP24 RSL24D1 0.0491
6326 60S ribosomal protein L13a RPL13A 0.0491
3205 Isocitrate lyase icl 0.0466
3078 Regulator of ribonuclease activity A Rv3853 0.0466
6335 60S ribosomal protein L3 RPL3 0.0463
6334 60S ribosomal protein L37 RPL37 0.0444
6231 Pepsin A PGA3 0.0398
6255 Carboxypeptidase A1 CPA1 0.0366
2248 Malate synthase G glcB 0.0335
3190 Malate synthase G glcB 0.0335
3184 3-methyl-2-oxobutanoate hydroxymethyltransferase panB 0.0331
3315 3-methyl-2-oxobutanoate hydroxymethyltransferase panB 0.0331
3179 2-isopropylmalate synthase leuA 0.0331
2424 L-lactate dehydrogenase ldh 0.03
2641 L-lactate dehydrogenase Not Available 0.03
4437 L-lactate dehydrogenase ldh 0.03
4442 L-lactate dehydrogenase ldh 0.03
126 D-lactate dehydrogenase dld 0.03
3545 D-lactate dehydrogenase Not Available 0.03
4510 D-lactate dehydrogenase ldhA 0.03
5650 NimA-related protein DR_0842 0.0289
3334 Deacetoxycephalosporin C synthetase cefE 0.0263
3178 Formate acetyltransferase 1 pflB 0.026
77 L-lactate dehydrogenase B chain LDHB 0.0232
3254 Bifunctional protein putA [Includes: Proline dehydrogenase putA 0.0228
473 L-lactate dehydrogenase A chain LDHA 0.0224
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0213
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.021
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.0198
860 Nicotinamide N-methyltransferase NNMT 0.0192
583 Nicotinate-nucleotide pyrophosphorylase [carboxylating] QPRT 0.0192
2442 Nicotinate-nucleotide pyrophosphorylase [carboxylating] nadC 0.0192
2459 Nicotinate-nucleotide pyrophosphorylase [carboxylating] nadC 0.0192
699 Nicotinic acid receptor 1 GPR109A 0.0192
928 Nicotinic acid receptor 2 GPR109B 0.0192
795 Branched-chain-amino-acid aminotransferase, mitochondrial BCAT2 0.0187
6151 Monocarboxylate transporter 10 SLC16A10 0.0174
397 Monocarboxylate transporter 3 SLC16A8 0.0125
195 Monocarboxylate transporter 7 SLC16A6 0.0122
429 Monocarboxylate transporter 6 SLC16A5 0.0121
218 Monocarboxylate transporter 5 SLC16A4 0.0121
52 Pyruvate kinase isozymes R/L PKLR 0.0108
771 Pyruvate carboxylase, mitochondrial PC 0.0097
98 Pyruvate kinase isozymes M1/M2 PKM2 0.0096
110 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.0093
114 Alanine--glyoxylate aminotransferase 2, mitochondrial AGXT2 0.0084
118 Organic cation/carnitine transporter 2 SLC22A5 0.0082
2775 Dihydroorotate dehydrogenase pyrD 0.0078
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0074
199 Monocarboxylate transporter 8 SLC16A2 0.0074
76 Nitric-oxide synthase, brain NOS1 0.0061
4119 Cytochrome P450 2D6 CYP2D6 0.0057
2586 Isopentenyl-diphosphate Delta-isomerase idi 0.0051
5187 Isopentenyl-diphosphate delta-isomerase fni 0.0051
5199 Isopentenyl-diphosphate delta-isomerase fni 0.0051
5170 Epidermin decarboxylase epiD 0.0051
5178 Protein nrdI nrdI 0.0051
5131 PhzG phzG 0.0051
3293 Flavodoxin Not Available 0.0051
4614 Flavodoxin DVU_2680 0.0051
5172 Flavodoxin isiB 0.0051
5173 Flavodoxin isiB 0.0051
5182 Flavodoxin fldA 0.0051
5175 Hypothetical protein SMU.260 SMU_260 0.0051
5202 Nitroreductase family protein BC_1844 0.0051
5197 Trp repressor binding protein WrbA, putative DR_A0214 0.0051
5201 FMN-binding protein DvMF_2023 0.0051
5193 Phenazine biosynthesis protein phzG phzG 0.0051
5181 Hypothetical protein yhdA azr 0.0051
5198 Flavodoxin-1 fldA 0.0051
5179 Probable aromatic acid decarboxylase pad1 0.0051
5200 NADH dehydrogenase nox 0.0051
5191 Morphinone reductase morB 0.0051
4405 Nitric oxide reductase fprA 0.0051
5190 Rubredoxin-oxygen oxidoreductase roo 0.0051
4037 Hypothetical protein GPX1 0.0047
4297 Hypothetical protein SP_1951 0.0047
4521 Hypothetical protein BC_2969 0.0047
4540 Hypothetical protein TM_1070 0.0047
4555 Hypothetical protein MT1739 0.0047
4569 Hypothetical protein mshD 0.0047
4578 Hypothetical protein PA3270 0.0047
4747 Hypothetical protein PA3967 0.0047
5177 Hypothetical protein TM_0096 0.0047
5194 Hypothetical protein PA1204 0.0047
5240 Hypothetical protein Rv2991 0.0047
5370 Hypothetical protein TM_1158 0.0047
5710 Hypothetical protein Tb927.5.1360 0.0047
4545 Molybdopterin-converting factor subunit 2 moaE 0.0047
4527 Putative hydrolase ycdX ycdX 0.0047
4106 Guanylate kinase GUK1 0.0047
4516 Guanylate kinase gmk 0.0047
4538 Hypothetical protein VC1899 VC_1899 0.0047
4536 Transcriptional regulator, IclR family TM_0065 0.0047
2501 Protein ygbM ygbM 0.0047
4514 Citrate lyase beta subunit-like protein citE 0.0047
4781 Citrate lyase beta subunit-like protein DR_1240 0.0047
4524 Mannose-6-phosphate isomerase yvyI 0.0047
4522 Arginine N-succinyltransferase subunit alpha astA 0.0047
4547 Iron binding protein FbpA fbpA 0.0047
4529 Oxalate decarboxylase oxdC oxdC 0.0047
4546 Aminotransferase, putative TM_1131 0.0047
658 Para-aminobenzoate synthase component 1 pabB 0.0047
4526 Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein TM_1223 0.0047
4535 Glutaconyl-CoA decarboxylase subunit alpha gcdA 0.0047
4548 Gyrase B gyrB 0.0047
4515 Peripheral plasma membrane protein CASK CASK 0.0047
4407 FMN-dependent NADH-azoreductase azoR 0.0044
5169 FMN-dependent NADH-azoreductase azoR 0.0044
5206 Phosphopantothenoylcysteine decarboxylase PPCDC 0.0044
4503 NADPH-flavin oxidoreductase frp 0.0044
3680 Dihydroorotate dehydrogenase A pyrDA 0.0044
3766 Pyridoxamine 5'-phosphate oxidase pdxH 0.0044
5176 YtnJ moxC 0.0044
3507 Chorismate synthase aroC 0.0044
5171 Chorismate synthase aroC 0.0044
5189 Trimethylamine dehydrogenase tmd 0.0044
4836 Ferredoxin-dependent glutamate synthase 2 gltS 0.0044
4496 C-terminal-binding protein 1 CTBP1 0.0043
810 Heme oxygenase 1 HMOX1 0.0041
3391 Heme oxygenase 1 pbsA1 0.0041
4532 Gephyrin GPHN 0.0041
6608 Serine/threonine-protein kinase Sgk1 SGK1 0.0041
56 Delta-aminolevulinic acid dehydratase ALAD 0.0041
2356 Delta-aminolevulinic acid dehydratase hemB 0.0041
3613 Delta-aminolevulinic acid dehydratase hemB 0.0041
3674 Delta-aminolevulinic acid dehydratase hemB 0.0041
4533 Glyoxalase family protein BC_1747 0.0041
3237 Beta-lactamase OXA-2 bla 0.0041
4542 Glutaminase 1 glsA1 0.0041
4544 Glutaminase 1 glsA1 0.0041
2929 (S)-2-haloacid dehalogenase dhlB 0.0041
2995 (S)-2-haloacid dehalogenase Not Available 0.0041
4528 Phenazine biosynthesis protein PhzD phzD1 0.0041
3759 Glutathione S-transferase gst 0.004
4541 Glutathione S-transferase GST 0.004
3261 Signal recognition particle protein ffh 0.004
4517 Probable butyrate kinase 2 buk2 0.004
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0039
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0039
3583 6-phosphogluconolactonase pgl 0.0037
3467 Methylglyoxal synthase mgsA 0.0037
408 Riboflavin kinase RFK 0.0037
4531 Putative ketoacyl reductase actIII 0.0037
2261 Major NAD(P)H-flavin oxidoreductase Not Available 0.0037
685 Oxygen-insensitive NADPH nitroreductase nfsA 0.0037
6945 Oxygen-insensitive NADPH nitroreductase rdxA 0.0037
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0036
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0036
203 Pyridoxine-5'-phosphate oxidase PNPO 0.0035
2525 3-phosphoshikimate 1-carboxyvinyltransferase aroA 0.0035
3201 3-phosphoshikimate 1-carboxyvinyltransferase aroA 0.0035
4284 Pentaerythritol tetranitrate reductase onr 0.0035
2688 Peptide deformylase def 0.0033
2708 Peptide deformylase def 0.0033
3004 Peptide deformylase def 0.0033
4337 Peptide deformylase def 0.0033
4338 Peptide deformylase def 0.0033
5368 Peptide deformylase def 0.0033
5371 Peptide deformylase def 0.0033
6375 Peptide deformylase def 0.0033
6378 Peptide deformylase def 0.0033
6379 Peptide deformylase def 0.0033
6776 Peptide deformylase def 0.0033
6900 Peptide deformylase def 0.0033
4534 Cytohesin-2 CYTH2 0.0033
2548 Subtilisin Carlsberg apr 0.0032
4269 Hypoxanthine-guanine phosphoribosyltransferase, putative HGPRTase 0.0032
654 Flavin reductase BLVRB 0.0031
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.003
760 Fibroblast growth factor 1 FGF1 0.0027
3027 Streptavidin Not Available 0.0027
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0026
4120 NADPH--cytochrome P450 reductase POR 0.0024
4916 Cyanoglobin glbN 0.0024
4915 Cytochrome c-550 psbV 0.0024
4959 Cytochrome c-550 psbV 0.0024
5216 Cytochrome c-550 psbV 0.0024
4943 Cytochrome c6 petJ 0.0024
4954 Soluble cytochrome b558 Not Available 0.0024
4905 Cytochrome c2 Not Available 0.0024
4939 Cytochrome c2 cycA 0.0024
4964 Cytochrome c2 cycA 0.0024
4979 Cytochrome c2 cycA 0.0024
6673 Cytochrome c2 cycA 0.0024
4961 Hemophore HasA hasA 0.0024
4936 Cytochrome c2 iso-2 Not Available 0.0024
4947 Bacterial hemoglobin vhb 0.0024
4975 Cytochrome c-556 RPA3973 0.0023
4942 Diheme cytochrome c napB napB 0.0023
3116 Bacterioferritin bfr 0.0023
4906 Bacterioferritin bfr 0.0023
4965 Bacterioferritin bfr 0.0023
4994 Hemoglobin-like protein HbO glbO 0.0023
4934 Cytochrome c-551 nirM 0.0023
5218 Cytochrome c-551 nirM 0.0023
4910 Cytoglobin CYGB 0.0023
4981 Iron-starvation protein PigA pigA 0.0023
4925 Cytochrome c-type protein SHP shp 0.0023
5000 HemO hemO 0.0023
4998 Hemoglobin-like protein yjbI yjbI 0.0023
4935 Cytochrome c-554 cycA1 0.0023
4999 Cytochrome P450 165B3 CYP165B3 0.0023
4984 Neuroglobin NGB 0.0023
4922 Cytochrome c, putative SO_4144 0.0023
4937 Cytochrome oxidase subunit II rcoxA 0.0023
4971 Nonaheme cytochrome c hmcA 0.0023
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0023
4989 Cytochrome c551 peroxidase ccp 0.0023
5222 Cytochrome c551 peroxidase ccpA 0.0023
4976 Apocytochrome f petA 0.0023
6407 Apocytochrome f petA 0.0023
4904 Cytochrome c family protein GSU1996 0.0023
4907 Cytochrome c-L moxG 0.0023
6865 Cytochrome c-L moxG 0.0023
4909 CooA protein cooA 0.0023
4972 P450cin cinA 0.0023
4764 Cytochrome P450 165C4 CYP165C4 0.0023
4960 Putative cytochrome P450-family protein SCO7417 0.0023
4931 Cytochrome P450 167A1 CYP167A1 0.0023
644 Heme oxygenase 2 HMOX2 0.0023
4982 Heme oxygenase 2 pbsA2 0.0023
4952 Catalase/peroxidase katA 0.0023
4993 Hydroxylamine oxidoreductase hao1 0.0023
4903 Methyl-accepting chemotaxis protein Tar4 0.0023
3093 Catalase HPII katE 0.0023
4926 Heme-based aerotactic transducer hemAT hemAT 0.0023
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0023
5682 Ribonuclease pancreatic RNASE1 0.0023
4990 PpcA ppcA 0.002
4385 Cytochrome c' Not Available 0.002
4967 Cytochrome c' cycA 0.002
5038 Cytochrome c' Not Available 0.002
5223 Cytochrome c' cycP 0.002
2119 Cytochrome b5 CYB5A 0.002
4948 Cytochrome c-553 Not Available 0.002
4813 Heme oxygenase hmuO 0.002
5769 Heme oxygenase Not Available 0.002
3375 Acidic cytochrome c3 Not Available 0.002
4923 Cytochrome c3 DvMF_2499 0.002
4945 Cytochrome c3 Not Available 0.002
4949 Cytochrome c3 DVU_3171 0.002
4968 Cytochrome c3 cytc3 0.002
4997 Cytochrome c3 SO_2727 0.002
5219 Cytochrome c3 cyd 0.002
4992 Cytochrome c peroxidase Not Available 0.002
4902 Nine-heme cytochrome c Ddes_2038 0.002
4289 Cytochrome P450 TT_P0059 0.002
6262 Cytochrome P450 staP 0.002
3570 Cytochrome P450 152A1 cypC 0.002
4920 Peroxidase/catalase katG 0.002
4988 Sulfite oxidase, mitochondrial SUOX 0.002
3189 High-molecular-weight cytochrome c hmcA 0.002
2915 Sensor protein fixL fixL 0.002
4944 Sensor protein fixL fixL 0.002
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.002
3670 Soluble cytochrome b562 precursor cybC 0.0019
4386 Hemoglobin-like protein HbN glbN 0.0019
3291 Cytochrome c-552 cycA 0.0019
4927 Cytochrome c-552 nrfA 0.0019
4938 Cytochrome c-552 cycA 0.0019
4953 Cytochrome c-552 nrfA 0.0019
5217 Cytochrome c-552 cycM 0.0019
3411 Cytochrome P450 121 cyp121 0.0019
3102 Flavohemoprotein hmp 0.0019
4969 Flavohemoprotein hmp 0.0019
2617 Nitric oxide synthase oxygenase nos 0.0019
2701 Nitric oxide synthase oxygenase nos 0.0019
3221 Cytochrome c4 cc4 0.0018
3127 Nitrite reductase nirS 0.0018
3284 Nitrite reductase nirS 0.0018
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0018
357 Carbonic anhydrase 2 CA2 0.0017
2230 Catalase CAT 0.0017
3249 Catalase katA 0.0017
3625 Catalase katA 0.0017
4539 Catalase katA 0.0017
4941 Catalase katB 0.0017
4608 Putative cytochrome P450 SCO1207 0.0017
4963 Putative cytochrome P450 SCO2884 0.0017
6254 Putative cytochrome P450 SCO6998 0.0017
605 Fumarate reductase flavoprotein subunit frdA 0.0016
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0016
3673 Fumarate reductase flavoprotein subunit fccA 0.0016
4912 Fumarate reductase flavoprotein subunit ifcA 0.0016
6549 Fumarate reductase flavoprotein subunit frdA 0.0016
2972 6-deoxyerythronolide B hydroxylase eryF 0.0016
260 Cytochrome P450 51 ERG11 0.0016
761 Cytochrome P450 51 ERG11 0.0016
3163 Cytochrome P450 51 cyp51 0.0016
1507 Cytochrome c CYCS 0.0015
693 Hemoglobin subunit beta HBB 0.0015
518 Peroxidase/catalase T katG 0.0015
2298 Cytochrome P450-cam camC 0.0013
358 Cystathionine beta-synthase CBS 0.0013
7 Nitric oxide synthase, inducible NOS2 0.0011
291 Nitric-oxide synthase, endothelial NOS3 0.0011
275 Arachidonate 5-lipoxygenase ALOX5 0.001
6106 Cytochrome P450 2C18 CYP2C18 0.0008
290 Prostaglandin G/H synthase 2 PTGS2 0.0007
20 Prostaglandin G/H synthase 1 PTGS1 0.0007
587 Serum albumin ALB 0.0007
6030 Cytochrome P450 2B6 CYP2B6 0.0006
4924 Cytochrome P450 2C8 CYP2C8 0.0006
4757 Cytochrome P450 2C9 CYP2C9 0.0005
4512 Cytochrome P450 3A4 CYP3A4 0.0005
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