DT-Web

DB02721 - 4-Iodopyrazole


Identification
Name 4-Iodopyrazole
Accession Number DB02721 (EXPT02726)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 192.9659
Groups experimental
Monoisotopic Weight 192.926266494
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Cytochrome P450 121
Name Cytochrome P450 121
Gene Name cyp121
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.9913
Alcohol dehydrogenase 1C
Name Alcohol dehydrogenase 1C
Gene Name ADH1C
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.5036
Alcohol dehydrogenase 1B
Name Alcohol dehydrogenase 1B
Gene Name ADH1B
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.8934
Alcohol dehydrogenase 1A
Name Alcohol dehydrogenase 1A
Gene Name ADH1A
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.6695

Predictions


Id Partner name Gene Name Score
2230 Catalase CAT 0.1095
3249 Catalase katA 0.1095
3625 Catalase katA 0.1095
4539 Catalase katA 0.1095
4941 Catalase katB 0.1095
396 Alcohol dehydrogenase 4 ADH4 0.0632
6013 Cytochrome P450 2E1 CYP2E1 0.0541
3381 Alcohol dehydrogenase Not Available 0.049
4508 Alcohol dehydrogenase adhA 0.049
5718 Cytochrome P450 2A6 CYP2A6 0.0407
1758 GTPase HRas HRAS 0.0355
820 Glycine receptor subunit alpha-2 GLRA2 0.0276
468 Cytochrome P450 4A11 CYP4A11 0.0257
482 Glycine receptor subunit alpha-1 GLRA1 0.024
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.021
6030 Cytochrome P450 2B6 CYP2B6 0.0166
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0159
6024 Cytochrome P450 1A1 CYP1A1 0.0153
4757 Cytochrome P450 2C9 CYP2C9 0.014
6016 Cytochrome P450 2C19 CYP2C19 0.013
3221 Cytochrome c4 cc4 0.0128
4200 Cytochrome P450 1A2 CYP1A2 0.0127
4512 Cytochrome P450 3A4 CYP3A4 0.0123
3191 Histidinol dehydrogenase hisD 0.0121
646 Malate dehydrogenase, cytoplasmic MDH1 0.0112
3116 Bacterioferritin bfr 0.0105
4906 Bacterioferritin bfr 0.0105
4965 Bacterioferritin bfr 0.0105
3709 Glycerol uptake facilitator protein glpF 0.0105
3393 TGF-beta receptor type-2 TGFBR2 0.0105
5489 Ribonucleoside-diphosphate reductase 1 subunit beta nrdB 0.0105
3238 Multidrug resistance protein mexA mexA 0.0105
3173 Enolase eno 0.0105
3336 C4-dicarboxylate transport transcriptional regulatory protein dctD dctD 0.0105
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0096
2852 DNA mismatch repair protein mutL mutL 0.0091
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0089
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0086
816 Biliverdin reductase A BLVRA 0.0085
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0085
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0085
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0085
6459 Glycodelin PAEP 0.0083
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0082
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.0079
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0079
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0079
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.0079
328 Sorbitol dehydrogenase SORD 0.0079
597 Dihydropteridine reductase QDPR 0.0078
363 NADP-dependent malic enzyme, mitochondrial ME3 0.0078
740 Argininosuccinate synthase ASS1 0.0078
865 Argininosuccinate synthase ASS1 0.0078
2680 Argininosuccinate synthase argG 0.0078
3194 Argininosuccinate synthase argG 0.0078
12 Alcohol dehydrogenase class 3 ADH5 0.0077
4311 tRNA TRDMT1 0.0076
4325 tRNA trmD 0.0076
4328 tRNA trmD 0.0076
4692 A/G-specific adenine glycosylase mutY 0.0076
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.0075
77 L-lactate dehydrogenase B chain LDHB 0.0074
2802 Endoglucanase G celCCG 0.0073
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.0072
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0072
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0072
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0072
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0072
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0072
473 L-lactate dehydrogenase A chain LDHA 0.0072
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.0071
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0071
666 NADP-dependent malic enzyme ME1 0.0071
6316 ADP-ribosylation factor 1 ARF1 0.0071
11 NAD(P) transhydrogenase, mitochondrial NNT 0.0068
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0068
810 Heme oxygenase 1 HMOX1 0.0066
3391 Heme oxygenase 1 pbsA1 0.0066
569 Retinal dehydrogenase 2 ALDH1A2 0.0065
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0065
611 Retinal dehydrogenase 1 ALDH1A1 0.0064
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0063
4925 Cytochrome c-type protein SHP shp 0.0062
4916 Cyanoglobin glbN 0.0062
4943 Cytochrome c6 petJ 0.0062
4934 Cytochrome c-551 nirM 0.0062
5218 Cytochrome c-551 nirM 0.0062
4936 Cytochrome c2 iso-2 Not Available 0.0062
4907 Cytochrome c-L moxG 0.0062
6865 Cytochrome c-L moxG 0.0062
4994 Hemoglobin-like protein HbO glbO 0.0062
4915 Cytochrome c-550 psbV 0.0062
4959 Cytochrome c-550 psbV 0.0062
5216 Cytochrome c-550 psbV 0.0062
4998 Hemoglobin-like protein yjbI yjbI 0.0062
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0062
4961 Hemophore HasA hasA 0.0062
4975 Cytochrome c-556 RPA3973 0.0062
4984 Neuroglobin NGB 0.0062
4954 Soluble cytochrome b558 Not Available 0.0062
4909 CooA protein cooA 0.0062
4905 Cytochrome c2 Not Available 0.0062
4939 Cytochrome c2 cycA 0.0062
4964 Cytochrome c2 cycA 0.0062
4979 Cytochrome c2 cycA 0.0062
6673 Cytochrome c2 cycA 0.0062
4910 Cytoglobin CYGB 0.0062
4972 P450cin cinA 0.0062
5000 HemO hemO 0.0062
4981 Iron-starvation protein PigA pigA 0.0062
4999 Cytochrome P450 165B3 CYP165B3 0.0062
4947 Bacterial hemoglobin vhb 0.0062
4764 Cytochrome P450 165C4 CYP165C4 0.0062
4960 Putative cytochrome P450-family protein SCO7417 0.0062
4942 Diheme cytochrome c napB napB 0.0062
4931 Cytochrome P450 167A1 CYP167A1 0.0062
4971 Nonaheme cytochrome c hmcA 0.0062
4989 Cytochrome c551 peroxidase ccp 0.0062
5222 Cytochrome c551 peroxidase ccpA 0.0062
4976 Apocytochrome f petA 0.0062
6407 Apocytochrome f petA 0.0062
4904 Cytochrome c family protein GSU1996 0.0062
4935 Cytochrome c-554 cycA1 0.0061
4926 Heme-based aerotactic transducer hemAT hemAT 0.0061
4922 Cytochrome c, putative SO_4144 0.0061
4952 Catalase/peroxidase katA 0.0061
3093 Catalase HPII katE 0.0061
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0061
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0061
4937 Cytochrome oxidase subunit II rcoxA 0.0061
4993 Hydroxylamine oxidoreductase hao1 0.0061
4903 Methyl-accepting chemotaxis protein Tar4 0.0061
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0061
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.006
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0059
4497 Benzyl alcohol dehydrogenase xylB 0.0059
4423 Levodione reductase lvr 0.0059
4428 Redox-sensing transcriptional repressor rex rex 0.0059
4500 L-lactate dehydrogenase 2 ldh2 0.0059
4449 ADP-ribosyltransferase Not Available 0.0059
4495 3-oxoacyl-(Acyl carrier protein) reductase TM_1169 0.0059
4435 L-aspartate dehydrogenase nadX 0.0059
4446 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase Not Available 0.0059
3729 Citrate synthase gltA 0.0059
4575 Citrate synthase cit 0.0059
4580 Citrate synthase gltA 0.0059
4505 Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase bphB 0.0059
4447 Hypothetical protein yhfP yhfP 0.0059
4336 Glyceraldehyde 3-phosphate dehydrogenase Not Available 0.0059
4436 Glyceraldehyde 3-phosphate dehydrogenase tthHB8IM 0.0059
4487 Transcriptional regulator nadR nadR 0.0059
3735 NAD(P) transhydrogenase subunit alpha part 1 pntAA 0.0059
4414 Dehydrogenase TT_P0035 0.0059
2350 3-isopropylmalate dehydrogenase leuB 0.0059
3092 3-isopropylmalate dehydrogenase leuB 0.0059
4418 AGR_L_3209p AGR_L_3209 0.0059
4507 Alanine dehydrogenase ald 0.0059
4475 Hypothetical protein Rv0046c/MT0052 ino1 0.0059
4506 Myo-inositol-1-phosphate synthase-related protein TM_1419 0.0059
4448 L-2-hydroxyisocaproate dehydrogenase Not Available 0.0059
4466 Glutathione-independent formaldehyde dehydrogenase fdhA 0.0059
4502 Formate dehydrogenase Not Available 0.0059
4455 Glycerol dehydrogenase gldA 0.0059
4451 Vip2Ac vip2Ac 0.0059
4472 Glucose 1-dehydrogenase Not Available 0.0059
4456 Inorganic polyphosphate/ATP-NAD kinase ppnK 0.0059
4443 Quinate/shikimate dehydrogenase ydiB 0.0059
4467 Alpha-glucosidase, putative TM_0752 0.0059
4471 CDP-D-glucose-4,6-dehydratase ascB 0.0059
654 Flavin reductase BLVRB 0.0057
714 Glutathione reductase, mitochondrial GSR 0.0055
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0055
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0054
4948 Cytochrome c-553 Not Available 0.0054
4923 Cytochrome c3 DvMF_2499 0.0054
4945 Cytochrome c3 Not Available 0.0054
4949 Cytochrome c3 DVU_3171 0.0054
4968 Cytochrome c3 cytc3 0.0054
4997 Cytochrome c3 SO_2727 0.0054
5219 Cytochrome c3 cyd 0.0054
4037 Hypothetical protein GPX1 0.0054
4297 Hypothetical protein SP_1951 0.0054
4521 Hypothetical protein BC_2969 0.0054
4540 Hypothetical protein TM_1070 0.0054
4555 Hypothetical protein MT1739 0.0054
4569 Hypothetical protein mshD 0.0054
4578 Hypothetical protein PA3270 0.0054
4747 Hypothetical protein PA3967 0.0054
5177 Hypothetical protein TM_0096 0.0054
5194 Hypothetical protein PA1204 0.0054
5240 Hypothetical protein Rv2991 0.0054
5370 Hypothetical protein TM_1158 0.0054
5710 Hypothetical protein Tb927.5.1360 0.0054
4990 PpcA ppcA 0.0054
4813 Heme oxygenase hmuO 0.0054
5769 Heme oxygenase Not Available 0.0054
3375 Acidic cytochrome c3 Not Available 0.0054
4385 Cytochrome c' Not Available 0.0054
4967 Cytochrome c' cycA 0.0054
5038 Cytochrome c' Not Available 0.0054
5223 Cytochrome c' cycP 0.0054
2119 Cytochrome b5 CYB5A 0.0054
3570 Cytochrome P450 152A1 cypC 0.0054
2915 Sensor protein fixL fixL 0.0054
4944 Sensor protein fixL fixL 0.0054
4992 Cytochrome c peroxidase Not Available 0.0054
4289 Cytochrome P450 TT_P0059 0.0054
6262 Cytochrome P450 staP 0.0054
4920 Peroxidase/catalase katG 0.0054
3189 High-molecular-weight cytochrome c hmcA 0.0054
4902 Nine-heme cytochrome c Ddes_2038 0.0054
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0054
4988 Sulfite oxidase, mitochondrial SUOX 0.0054
76 Nitric-oxide synthase, brain NOS1 0.0053
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0052
904 Glutathione S-transferase P GSTP1 0.005
4386 Hemoglobin-like protein HbN glbN 0.005
3291 Cytochrome c-552 cycA 0.0049
4927 Cytochrome c-552 nrfA 0.0049
4938 Cytochrome c-552 cycA 0.0049
4953 Cytochrome c-552 nrfA 0.0049
5217 Cytochrome c-552 cycM 0.0049
3670 Soluble cytochrome b562 precursor cybC 0.0049
3102 Flavohemoprotein hmp 0.0049
4969 Flavohemoprotein hmp 0.0049
2617 Nitric oxide synthase oxygenase nos 0.0049
2701 Nitric oxide synthase oxygenase nos 0.0049
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0049
4427 TDP-glucose-4,6-dehydratase desIV 0.0048
3177 dTDP-glucose 4,6-dehydratase rfbB 0.0048
4499 dTDP-glucose 4,6-dehydratase rmlB 0.0048
3598 dTDP-4-dehydrorhamnose reductase rfbD 0.0048
4486 Phenol 2-hydroxylase component B pheA2 0.0048
4439 Ferredoxin reductase bphA4 0.0048
4477 Dihydrolipoyl dehydrogenase lpdV 0.0048
5077 Dihydrolipoyl dehydrogenase Not Available 0.0048
5117 Dihydrolipoyl dehydrogenase lpd 0.0048
2967 CDP-paratose 2-epimerase rfbE 0.0048
4482 UDP-galactose 4-epimerase galE 0.0048
4503 NADPH-flavin oxidoreductase frp 0.0048
2507 Diphtheria toxin Not Available 0.0048
4509 Acetoin(diacetyl) reductase budC 0.0047
1199 GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 ART1 0.0047
3615 Dihydrodipicolinate reductase dapB 0.0047
3618 Dihydrodipicolinate reductase dapB 0.0047
4462 Dihydrodipicolinate reductase dapB 0.0047
2591 Urocanate hydratase hutU 0.0047
2393 Maltose-6'-phosphate glucosidase glvA 0.0047
2538 6-phospho-beta-glucosidase bglT bglT 0.0047
3081 3-dehydroquinate synthase aroB 0.0047
6698 Dehydrogenase/reductase SDR family member 4-like 2 DHRS4L2 0.0047
126 D-lactate dehydrogenase dld 0.0047
3545 D-lactate dehydrogenase Not Available 0.0047
4510 D-lactate dehydrogenase ldhA 0.0047
3671 7-alpha-hydroxysteroid dehydrogenase hdhA 0.0047
4450 Iota toxin component Ia Not Available 0.0047
2424 L-lactate dehydrogenase ldh 0.0047
2641 L-lactate dehydrogenase Not Available 0.0047
4437 L-lactate dehydrogenase ldh 0.0047
4442 L-lactate dehydrogenase ldh 0.0047
2831 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase Not Available 0.0047
3059 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase fabG3 0.0047
3401 D-2-hydroxyisocaproate dehydrogenase Not Available 0.0047
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0047
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0047
4496 C-terminal-binding protein 1 CTBP1 0.0047
2881 Gamma-aminobutyraldehyde dehydrogenase prr 0.0047
2018 Deoxyhypusine synthase DHPS 0.0047
2336 2,3-diketo-L-gulonate reductase dlgD 0.0047
4498 Ornithine cyclodeaminase PP3533 0.0047
3127 Nitrite reductase nirS 0.0047
3284 Nitrite reductase nirS 0.0047
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0047
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0046
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0046
822 Aldose reductase AKR1B1 0.0045
2683 Mono-ADP-ribosyltransferase C3 C3 0.0045
4608 Putative cytochrome P450 SCO1207 0.0045
4963 Putative cytochrome P450 SCO2884 0.0045
6254 Putative cytochrome P450 SCO6998 0.0045
605 Fumarate reductase flavoprotein subunit frdA 0.0044
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0044
3673 Fumarate reductase flavoprotein subunit fccA 0.0044
4912 Fumarate reductase flavoprotein subunit ifcA 0.0044
6549 Fumarate reductase flavoprotein subunit frdA 0.0044
2972 6-deoxyerythronolide B hydroxylase eryF 0.0044
4504 WbpP Not Available 0.0043
3296 Nicotinamide mononucleotide adenylyltransferase 1 NMNAT1 0.0043
365 Dihydrofolate reductase DHFR 0.0043
2381 Dihydrofolate reductase DFR1 0.0043
2833 Dihydrofolate reductase Not Available 0.0043
2931 Dihydrofolate reductase folA 0.0043
3544 Dihydrofolate reductase folA 0.0043
3682 Dihydrofolate reductase folA 0.0043
6642 Dihydrofolate reductase folA 0.0043
6756 Dihydrofolate reductase dfrA 0.0043
3367 GDP-mannose 6-dehydrogenase algD 0.0043
2391 Ferrochelatase hemH 0.0043
6502 Ferrochelatase DKFZp686P18130 0.0043
1591 Ferrochelatase, mitochondrial FECH 0.0043
4440 NADH peroxidase npr 0.0043
4318 Siroheme synthase cysG 0.0043
4343 Alpha-glucosidase aglA 0.0042
2799 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal Not Available 0.0042
3736 Glyceraldehyde-3-phosphate dehydrogenase A gapA 0.0042
4476 Mannitol dehydrogenase mtlD 0.0042
63 Malate dehydrogenase mdh 0.0042
2329 Malate dehydrogenase mdh 0.0042
3445 Malate dehydrogenase mdh 0.0042
4420 Malate dehydrogenase mdh 0.0042
4438 Malate dehydrogenase mdh 0.0042
5322 Oxidoreductase ydhF ydhF 0.0042
3772 3-oxoacyl-[acyl-carrier-protein] reductase fabG 0.0042
5326 Oxidoreductase, short chain dehydrogenase/reductase family TM_0441 0.0042
5332 MtdA bifunctional protein mtdA 0.0042
5330 General stress protein 69 yhdN 0.0042
5333 Alcohol dehydrogenase, iron-containing TM_0920 0.0042
5342 NADH-dependent butanol dehydrogenase, putative TM_0820 0.0042
5157 Dehydrogenase/reductase SDR family member 11 DHRS11 0.0042
3778 NAD(P) transhydrogenase subunit beta pntB 0.0042
5346 Oxidoreductase, aldo/keto reductase family TM_1009 0.0042
5343 NADP-dependent fatty aldehyde dehydrogenase aldH 0.0042
4403 Protein iolS iolS 0.0042
260 Cytochrome P450 51 ERG11 0.0042
761 Cytochrome P450 51 ERG11 0.0042
3163 Cytochrome P450 51 cyp51 0.0042
518 Peroxidase/catalase T katG 0.0042
2826 Glucose--fructose oxidoreductase gfo 0.004
1507 Cytochrome c CYCS 0.004
3333 Nicotinamide mononucleotide adenylyltransferase 3 NMNAT3 0.004
2434 NH(3)-dependent NAD(+) synthetase nadE 0.004
2910 NH(3)-dependent NAD(+) synthetase nadE 0.004
3217 NH(3)-dependent NAD(+) synthetase nadE 0.004
3070 Adenosylhomocysteinase AHCY 0.004
4424 Adenosylhomocysteinase PFE1050w 0.004
6278 Adenosylhomocysteinase ahcY 0.004
353 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 NDUFA4L2 0.004
598 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NDUFA11 0.004
313 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NDUFB3 0.004
300 NADH-ubiquinone oxidoreductase chain 4L MT-ND4L 0.004
374 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NDUFB1 0.004
475 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NDUFB2 0.004
190 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 NDUFA4 0.004
30 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NDUFV3 0.004
247 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUFA1 0.004
607 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NDUFA2 0.004
417 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NDUFB6 0.004
343 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NDUFC1 0.004
755 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NDUFA3 0.004
602 Acyl carrier protein, mitochondrial NDUFAB1 0.004
405 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NDUFA8 0.004
446 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NDUFA7 0.004
99 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NDUFS5 0.004
525 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NDUFA5 0.004
219 NADH-ubiquinone oxidoreductase chain 3 MT-ND3 0.004
41 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NDUFS8 0.004
104 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NDUFS6 0.004
236 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NDUFA6 0.004
555 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 0.004
324 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NDUFB4 0.004
568 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NDUFB7 0.004
152 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NDUFV2 0.004
582 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NDUFA13 0.004
829 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NDUFA12 0.004
609 15-hydroxyprostaglandin dehydrogenase [NAD+] HPGD 0.004
384 NADH-ubiquinone oxidoreductase chain 6 MT-ND6 0.004
608 NADH-ubiquinone oxidoreductase chain 4 MT-ND4 0.004
270 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NDUFB5 0.004
272 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NDUFB10 0.004
372 Estradiol 17-beta-dehydrogenase 3 HSD17B3 0.004
14 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial IDH3A 0.004
656 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 0.004
196 D-beta-hydroxybutyrate dehydrogenase, mitochondrial BDH1 0.004
729 GDP-L-fucose synthetase TSTA3 0.004
3463 GDP-L-fucose synthetase fcl 0.004
487 Aldo-keto reductase family 1 member C4 AKR1C4 0.004
746 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NDUFB8 0.004
167 L-lactate dehydrogenase C chain LDHC 0.004
141 3-hydroxyisobutyrate dehydrogenase, mitochondrial HIBADH 0.004
288 Trifunctional enzyme subunit alpha, mitochondrial HADHA 0.004
258 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial ALDH6A1 0.004
721 NADH-ubiquinone oxidoreductase chain 2 MT-ND2 0.004
231 Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic GPD1 0.004
91 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NDUFA10 0.004
112 L-lactate dehydrogenase A-like 6B LDHAL6B 0.004
216 Aldehyde dehydrogenase 3B2 ALDH3B2 0.004
616 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial IDH3B 0.004
107 C-4 methylsterol oxidase SC4MOL 0.004
9 Estradiol 17-beta-dehydrogenase 2 HSD17B2 0.004
671 Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial PDHA2 0.004
628 Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial PDHA1 0.004
848 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial IDH3G 0.004
145 Corticosteroid 11-beta-dehydrogenase isozyme 2 HSD11B2 0.004
50 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating NSDHL 0.004
271 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial ALDH4A1 0.004
206 3-keto-steroid reductase HSD17B7 0.004
496 Aldehyde dehydrogenase 3B1 ALDH3B1 0.004
531 Aldehyde dehydrogenase X, mitochondrial ALDH1B1 0.004
662 Fatty aldehyde dehydrogenase ALDH3A2 0.004
711 UDP-glucose 6-dehydrogenase UGDH 0.004
3672 UDP-glucose 6-dehydrogenase hasB 0.004
149 Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 0.004
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.004
3726 D-3-phosphoglycerate dehydrogenase serA 0.004
4291 D-3-phosphoglycerate dehydrogenase serA 0.004
335 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NDUFA9 0.004
644 Heme oxygenase 2 HMOX2 0.004
4982 Heme oxygenase 2 pbsA2 0.004
326 L-lactate dehydrogenase A-like 6A LDHAL6A 0.004
637 NADH-ubiquinone oxidoreductase chain 5 MT-ND5 0.004
327 Glutathione reductase gor 0.004
5110 Glutathione reductase GR2 0.004
643 Peroxisomal bifunctional enzyme EHHADH 0.004
548 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NDUFS1 0.004
34 7-dehydrocholesterol reductase DHCR7 0.004
393 GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase H6PD 0.004
539 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NDUFV1 0.004
693 Hemoglobin subunit beta HBB 0.0039
6268 Hydroxyacid oxidase 1 HAO1 0.0039
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0038
857 Malate dehydrogenase, mitochondrial MDH2 0.0038
6495 Cytochrome c oxidase subunit 7C, mitochondrial COX7C 0.0037
6494 Cytochrome c oxidase subunit 7B, mitochondrial COX7B 0.0037
6496 Cytochrome c oxidase subunit 8A, mitochondrial COX8A 0.0037
6493 Cytochrome c oxidase subunit 6C COX6C 0.0037
6499 Cytochrome c oxidase polypeptide 7A1, mitochondrial COX7A1 0.0037
6491 Cytochrome c oxidase subunit 5A, mitochondrial COX5A 0.0037
6497 Cytochrome c oxidase subunit 6A2, mitochondrial COX6A2 0.0037
6489 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial COX4I1 0.0037
371 Cytochrome c oxidase subunit 1 MT-CO1 0.0037
6558 Cytochrome c oxidase subunit 1 ctaD 0.0037
6498 Cytochrome c oxidase subunit 6B1 COX6B1 0.0037
5793 Cytochrome c oxidase subunit 2 MT-CO2 0.0037
6559 Cytochrome c oxidase subunit 2 ctaC 0.0037
6669 Cytochrome c oxidase subunit 2 ctaC 0.0037
6490 Cytochrome c oxidase subunit 3 MT-CO3 0.0037
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0037
2375 ADP-L-glycero-D-manno-heptose-6-epimerase hldD 0.0037
1588 Multidrug resistance protein 1 ABCB1 0.0037
5073 Ferredoxin--NADP reductase petH 0.0037
5076 Ferredoxin--NADP reductase fpr 0.0037
5119 Ferredoxin--NADP reductase petH 0.0037
5121 Ferredoxin--NADP reductase fpr 0.0037
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0037
3446 NADP-dependent alcohol dehydrogenase adh 0.0036
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.0036
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.0036
4582 Putative pteridine reductase 2 ptr2 0.0036
4628 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase gapN 0.0036
74 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial DLAT 0.0036
989 L-xylulose reductase DCXR 0.0036
2636 Shikimate dehydrogenase aroE 0.0036
3515 Shikimate dehydrogenase aroE 0.0036
5328 Prostaglandin F synthase Tb11.02.2310 0.0036
2305 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 0.0036
4491 DNA ligase, NAD-dependent ligA 0.0036
2286 Isocitrate dehydrogenase [NADP] icd 0.0036
2302 Isocitrate dehydrogenase [NADP] icd 0.0036
2771 Isocitrate dehydrogenase [NADP] icd 0.0036
2762 UDP-glucose 4-epimerase GALE 0.0035
3461 UDP-glucose 4-epimerase galE 0.0035
358 Cystathionine beta-synthase CBS 0.0035
6026 Alcohol dehydrogenase 6 ADH6 0.0035
3587 Gastrotropin FABP6 0.0034
2540 Choloylglycine hydrolase cbh 0.0034
2298 Cytochrome P450-cam camC 0.0034
296 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial MTHFD2 0.0033
13 Aminomethyltransferase, mitochondrial AMT 0.0033
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0033
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0033
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0033
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0033
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0033
248 Pyrroline-5-carboxylate reductase 1 PYCR1 0.0033
802 Pyrroline-5-carboxylate reductase 2 PYCR2 0.0033
627 11-cis retinol dehydrogenase RDH5 0.0033
640 Aldehyde dehydrogenase 1A3 ALDH1A3 0.0033
6297 Prostaglandin reductase 1 PTGR1 0.0033
6862 Aldo-keto reductase family 1 member B10 AKR1B10 0.0033
4531 Putative ketoacyl reductase actIII 0.0033
3062 Aspartate-semialdehyde dehydrogenase asd 0.0033
626 Cysteine dioxygenase type 1 CDO1 0.0033
110 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.0033
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0033
6501 Fatty acid-binding protein, liver FABP1 0.0032
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0032
2675 Pteridine reductase 1 PTR1 0.0032
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0032
2159 Quinone oxidoreductase CRYZ 0.0031
1124 Sepiapterin reductase SPR 0.0031
57 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I HSD3B1 0.003
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0029
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0029
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0029
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0029
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0029
275 Arachidonate 5-lipoxygenase ALOX5 0.0029
279 Tyrosinase TYR 0.0029
7 Nitric oxide synthase, inducible NOS2 0.0028
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0028
291 Nitric-oxide synthase, endothelial NOS3 0.0028
380 Cytochrome P450 17A1 CYP17A1 0.0027
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0027
3809 Estrogen-related receptor gamma ESRRG 0.0026
6500 Phospholipase A2 PLA2G1B 0.0026
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0025
6106 Cytochrome P450 2C18 CYP2C18 0.0024
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0024
6020 Aldehyde oxidase AOX1 0.0023
3947 Xanthine dehydrogenase/oxidase XDH 0.0021
290 Prostaglandin G/H synthase 2 PTGS2 0.0021
4120 NADPH--cytochrome P450 reductase POR 0.0021
20 Prostaglandin G/H synthase 1 PTGS1 0.002
6141 Sodium/bile acid cotransporter SLC10A1 0.0019
4604 Liver carboxylesterase 1 CES1 0.0019
587 Serum albumin ALB 0.0019
4924 Cytochrome P450 2C8 CYP2C8 0.0017
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0017
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0016
776 Bile salt export pump ABCB11 0.0015
6143 Solute carrier family 22 member 7 SLC22A7 0.0015
2164 Multidrug resistance-associated protein 4 ABCC4 0.0015
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0014
862 Multidrug resistance-associated protein 1 ABCC1 0.0014
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0014
6142 Solute carrier family 22 member 8 SLC22A8 0.0013
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0013
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