Identification
Name 2-Oxo-4-Methylpentanoic Acid
Accession Number DB03229 (EXPT00985)
Type small molecule
Description Not Available
Structure
Categories (*)
Molecular Weight 130.1418
Groups experimental
Monoisotopic Weight 130.062994186
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available
Deacetoxycephalosporin C synthetase
Name Deacetoxycephalosporin C synthetase
Gene Name cefE
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.488
D-2-hydroxyisocaproate dehydrogenase
Name D-2-hydroxyisocaproate dehydrogenase
Gene Name Not Available
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.815
Id Partner name Gene Name Score
3184 3-methyl-2-oxobutanoate hydroxymethyltransferase panB 0.1011
3315 3-methyl-2-oxobutanoate hydroxymethyltransferase panB 0.1011
3179 2-isopropylmalate synthase leuA 0.101
489 Monocarboxylate transporter 2 SLC16A7 0.0577
500 Monocarboxylate transporter 4 SLC16A3 0.0573
795 Branched-chain-amino-acid aminotransferase, mitochondrial BCAT2 0.0548
738 Monocarboxylate transporter 1 SLC16A1 0.0432
4443 Quinate/shikimate dehydrogenase ydiB 0.0069
4428 Redox-sensing transcriptional repressor rex rex 0.0069
4449 ADP-ribosyltransferase Not Available 0.0069
4446 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase Not Available 0.0069
4472 Glucose 1-dehydrogenase Not Available 0.0069
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.0069
3726 D-3-phosphoglycerate dehydrogenase serA 0.0069
4291 D-3-phosphoglycerate dehydrogenase serA 0.0069
4423 Levodione reductase lvr 0.0069
4505 Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase bphB 0.0069
4456 Inorganic polyphosphate/ATP-NAD kinase ppnK 0.0069
4448 L-2-hydroxyisocaproate dehydrogenase Not Available 0.0069
4447 Hypothetical protein yhfP yhfP 0.0069
4336 Glyceraldehyde 3-phosphate dehydrogenase Not Available 0.0069
4436 Glyceraldehyde 3-phosphate dehydrogenase tthHB8IM 0.0069
3381 Alcohol dehydrogenase Not Available 0.0069
4508 Alcohol dehydrogenase adhA 0.0069
4414 Dehydrogenase TT_P0035 0.0069
4475 Hypothetical protein Rv0046c/MT0052 ino1 0.0069
4471 CDP-D-glucose-4,6-dehydratase ascB 0.0069
4418 AGR_L_3209p AGR_L_3209 0.0069
4507 Alanine dehydrogenase ald 0.0069
4455 Glycerol dehydrogenase gldA 0.0069
4497 Benzyl alcohol dehydrogenase xylB 0.0069
4506 Myo-inositol-1-phosphate synthase-related protein TM_1419 0.0069
3735 NAD(P) transhydrogenase subunit alpha part 1 pntAA 0.0069
4466 Glutathione-independent formaldehyde dehydrogenase fdhA 0.0069
4502 Formate dehydrogenase Not Available 0.0069
4487 Transcriptional regulator nadR nadR 0.0069
4495 3-oxoacyl-(Acyl carrier protein) reductase TM_1169 0.0069
3729 Citrate synthase gltA 0.0069
4575 Citrate synthase cit 0.0069
4580 Citrate synthase gltA 0.0069
4435 L-aspartate dehydrogenase nadX 0.0069
4451 Vip2Ac vip2Ac 0.0069
4467 Alpha-glucosidase, putative TM_0752 0.0069
4500 L-lactate dehydrogenase 2 ldh2 0.0069
2350 3-isopropylmalate dehydrogenase leuB 0.0069
3092 3-isopropylmalate dehydrogenase leuB 0.0069
126 D-lactate dehydrogenase dld 0.006
3545 D-lactate dehydrogenase Not Available 0.006
4510 D-lactate dehydrogenase ldhA 0.006
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.006
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.006
4503 NADPH-flavin oxidoreductase frp 0.006
4486 Phenol 2-hydroxylase component B pheA2 0.006
3671 7-alpha-hydroxysteroid dehydrogenase hdhA 0.006
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.006
3615 Dihydrodipicolinate reductase dapB 0.006
3618 Dihydrodipicolinate reductase dapB 0.006
4462 Dihydrodipicolinate reductase dapB 0.006
4482 UDP-galactose 4-epimerase galE 0.006
2831 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase Not Available 0.006
3059 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase fabG3 0.006
4509 Acetoin(diacetyl) reductase budC 0.006
4477 Dihydrolipoyl dehydrogenase lpdV 0.006
5077 Dihydrolipoyl dehydrogenase Not Available 0.006
5117 Dihydrolipoyl dehydrogenase lpd 0.006
3598 dTDP-4-dehydrorhamnose reductase rfbD 0.006
2424 L-lactate dehydrogenase ldh 0.006
2641 L-lactate dehydrogenase Not Available 0.006
4437 L-lactate dehydrogenase ldh 0.006
4442 L-lactate dehydrogenase ldh 0.006
1199 GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 ART1 0.006
2336 2,3-diketo-L-gulonate reductase dlgD 0.006
4427 TDP-glucose-4,6-dehydratase desIV 0.006
2967 CDP-paratose 2-epimerase rfbE 0.006
4498 Ornithine cyclodeaminase PP3533 0.006
3081 3-dehydroquinate synthase aroB 0.006
2507 Diphtheria toxin Not Available 0.006
3177 dTDP-glucose 4,6-dehydratase rfbB 0.006
4499 dTDP-glucose 4,6-dehydratase rmlB 0.006
2018 Deoxyhypusine synthase DHPS 0.006
4439 Ferredoxin reductase bphA4 0.006
6698 Dehydrogenase/reductase SDR family member 4-like 2 DHRS4L2 0.006
2538 6-phospho-beta-glucosidase bglT bglT 0.006
4496 C-terminal-binding protein 1 CTBP1 0.006
2393 Maltose-6'-phosphate glucosidase glvA 0.006
4450 Iota toxin component Ia Not Available 0.006
2881 Gamma-aminobutyraldehyde dehydrogenase prr 0.006
2591 Urocanate hydratase hutU 0.006
4343 Alpha-glucosidase aglA 0.0055
3736 Glyceraldehyde-3-phosphate dehydrogenase A gapA 0.0055
3367 GDP-mannose 6-dehydrogenase algD 0.0055
4504 WbpP Not Available 0.0055
711 UDP-glucose 6-dehydrogenase UGDH 0.0055
3672 UDP-glucose 6-dehydrogenase hasB 0.0055
2683 Mono-ADP-ribosyltransferase C3 C3 0.0055
4440 NADH peroxidase npr 0.0055
4318 Siroheme synthase cysG 0.0055
3296 Nicotinamide mononucleotide adenylyltransferase 1 NMNAT1 0.0055
2799 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal Not Available 0.0055
4476 Mannitol dehydrogenase mtlD 0.0054
63 Malate dehydrogenase mdh 0.0054
2329 Malate dehydrogenase mdh 0.0054
3445 Malate dehydrogenase mdh 0.0054
4420 Malate dehydrogenase mdh 0.0054
4438 Malate dehydrogenase mdh 0.0054
816 Biliverdin reductase A BLVRA 0.0054
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0054
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0054
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0054
2434 NH(3)-dependent NAD(+) synthetase nadE 0.0052
2910 NH(3)-dependent NAD(+) synthetase nadE 0.0052
3217 NH(3)-dependent NAD(+) synthetase nadE 0.0052
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.0052
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.0052
3070 Adenosylhomocysteinase AHCY 0.0052
4424 Adenosylhomocysteinase PFE1050w 0.0052
6278 Adenosylhomocysteinase ahcY 0.0052
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.0052
2826 Glucose--fructose oxidoreductase gfo 0.0052
3191 Histidinol dehydrogenase hisD 0.0052
3333 Nicotinamide mononucleotide adenylyltransferase 3 NMNAT3 0.0052
2617 Nitric oxide synthase oxygenase nos 0.0052
2701 Nitric oxide synthase oxygenase nos 0.0052
327 Glutathione reductase gor 0.0052
5110 Glutathione reductase GR2 0.0052
396 Alcohol dehydrogenase 4 ADH4 0.0052
597 Dihydropteridine reductase QDPR 0.0052
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.0052
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0052
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0052
646 Malate dehydrogenase, cytoplasmic MDH1 0.0052
363 NADP-dependent malic enzyme, mitochondrial ME3 0.0052
328 Sorbitol dehydrogenase SORD 0.0052
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.0052
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.005
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.005
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.005
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.005
77 L-lactate dehydrogenase B chain LDHB 0.005
12 Alcohol dehydrogenase class 3 ADH5 0.005
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0048
2286 Isocitrate dehydrogenase [NADP] icd 0.0048
2302 Isocitrate dehydrogenase [NADP] icd 0.0048
2771 Isocitrate dehydrogenase [NADP] icd 0.0048
4491 DNA ligase, NAD-dependent ligA 0.0048
473 L-lactate dehydrogenase A chain LDHA 0.0048
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0048
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0048
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0048
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0048
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0048
2762 UDP-glucose 4-epimerase GALE 0.0047
3461 UDP-glucose 4-epimerase galE 0.0047
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0047
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0046
569 Retinal dehydrogenase 2 ALDH1A2 0.0044
611 Retinal dehydrogenase 1 ALDH1A1 0.0044
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0043
251 Alcohol dehydrogenase 1A ADH1A 0.0043
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0042
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0041
444 Alcohol dehydrogenase 1B ADH1B 0.0041
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0039
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0039
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0039
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0039
714 Glutathione reductase, mitochondrial GSR 0.0039
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0038
517 Alcohol dehydrogenase 1C ADH1C 0.0037