DT-Web

DB01677 - Fumarate


Identification
Name Fumarate
Accession Number DB01677 (EXPT01460, EXPT01511)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 114.0563
Groups experimental
Monoisotopic Weight 113.995308552
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Malate dehydrogenase
Name Malate dehydrogenase
Gene Name mdh
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.0075
Fumarate reductase flavoprotein subunit
Name Fumarate reductase flavoprotein subunit
Gene Name fccA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.5257
Fumarate reductase flavoprotein subunit
Name Fumarate reductase flavoprotein subunit
Gene Name SO_0970
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.5257
NAD-dependent malic enzyme, mitochondrial
Name NAD-dependent malic enzyme, mitochondrial
Gene Name ME2
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.9391
Fumarylacetoacetase
Name Fumarylacetoacetase
Gene Name FAH
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available

Predictions


Id Partner name Gene Name Score
605 Fumarate reductase flavoprotein subunit frdA 0.5257
4912 Fumarate reductase flavoprotein subunit ifcA 0.5257
6549 Fumarate reductase flavoprotein subunit frdA 0.5257
363 NADP-dependent malic enzyme, mitochondrial ME3 0.1558
2891 Circadian clock protein kaiB kaiB 0.0659
2248 Malate synthase G glcB 0.0614
3190 Malate synthase G glcB 0.0614
4384 Capsule biosynthesis protein synC 0.0608
3486 Fumarate hydratase class II fumC 0.0574
2499 Tubulin beta-2C chain TUBB2C 0.0512
2449 Tubulin alpha-3 chain TUBA1A 0.0466
6024 Cytochrome P450 1A1 CYP1A1 0.0239
4200 Cytochrome P450 1A2 CYP1A2 0.0199
1588 Multidrug resistance protein 1 ABCB1 0.0194
4486 Phenol 2-hydroxylase component B pheA2 0.0194
4439 Ferredoxin reductase bphA4 0.0194
4477 Dihydrolipoyl dehydrogenase lpdV 0.0194
5077 Dihydrolipoyl dehydrogenase Not Available 0.0194
5117 Dihydrolipoyl dehydrogenase lpd 0.0194
4512 Cytochrome P450 3A4 CYP3A4 0.0189
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0185
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0185
4440 NADH peroxidase npr 0.0177
3102 Flavohemoprotein hmp 0.017
4969 Flavohemoprotein hmp 0.017
327 Glutathione reductase gor 0.0163
5110 Glutathione reductase GR2 0.0163
714 Glutathione reductase, mitochondrial GSR 0.0136
5081 L-aspartate oxidase nadB 0.0123
5115 FkbI fkbI 0.0123
5122 Mersacidin decarboxylase mrsD 0.0123
5078 Amine oxidase, flavin-containing PSPTO1126 0.0123
526 Thioredoxin reductase trxB 0.0123
3767 Thioredoxin reductase trxB 0.0123
5107 Alkyl hydroperoxide reductase subunit F ahpF 0.0123
5118 Alkyl hydroperoxide reductase subunit F ahpF 0.0123
5095 Putidaredoxin reductase camA 0.0123
3133 UDP-galactopyranose mutase glf 0.0123
5099 UDP-galactopyranose mutase glf 0.0123
3763 5,10-methylenetetrahydrofolate reductase metF 0.0123
3918 5,10-methylenetetrahydrofolate reductase MTHFR 0.0123
5094 5,10-methylenetetrahydrofolate reductase metF 0.0123
1329 Apoptosis-inducing factor 1, mitochondrial AIFM1 0.0123
5112 Benzoate 1,2-dioxygenase electron transfer component benC 0.0123
5097 PROBABLE DIHYDROLIPOAMIDE DEHYDROGENASE LPDA lpdA 0.0123
5114 Putative acyl-CoA dehydrogenase TT_C0779 0.0123
5111 Phenylacetone monooxygenase pamO 0.0123
5109 Outer membrane protein p64k or PM-6 m-6 0.0123
5083 Cryptochrome DASH cry 0.0123
5100 Gamma-aminobutyrate metabolism dehydratase/isomerase abfD 0.0123
5102 4-cresol dehydrogenase [hydroxylating] flavoprotein subunit pchF 0.0123
1410 Oxidoreductase HSD17B6 0.0123
4725 Oxidoreductase Not Available 0.0123
5124 Oxidoreductase Not Available 0.0123
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0111
3594 Deoxyribodipyrimidine photo-lyase phr 0.0107
5079 Deoxyribodipyrimidine photo-lyase phrB 0.0107
5080 Deoxyribodipyrimidine photo-lyase phr 0.0107
5091 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0107
5093 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0107
2470 Pyruvate oxidase pox5 0.0107
5072 N,N-dimethylglycine oxidase dmg 0.0107
3506 Glutaryl-CoA dehydrogenase, mitochondrial GCDH 0.0107
5003 Acyl-CoA dehydrogenase, short-chain specific Not Available 0.0107
440 Isovaleryl-CoA dehydrogenase, mitochondrial IVD 0.0107
2526 NADPH-ferredoxin reductase fprA fprA 0.0107
667 Acyl-CoA dehydrogenase family member 8, mitochondrial ACAD8 0.0107
5073 Ferredoxin--NADP reductase petH 0.0107
5076 Ferredoxin--NADP reductase fpr 0.0107
5119 Ferredoxin--NADP reductase petH 0.0107
5121 Ferredoxin--NADP reductase fpr 0.0107
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0107
3247 2-oxopropyl-CoM reductase, carboxylating xecC 0.0107
6639 Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 0.0107
76 Nitric-oxide synthase, brain NOS1 0.0106
2268 Cholesterol oxidase choB 0.0106
2822 Cholesterol oxidase choA 0.0106
3185 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM 0.0098
2893 Glycine oxidase thiO 0.0098
3254 Bifunctional protein putA [Includes: Proline dehydrogenase putA 0.0098
4500 L-lactate dehydrogenase 2 ldh2 0.0098
4467 Alpha-glucosidase, putative TM_0752 0.0098
4495 3-oxoacyl-(Acyl carrier protein) reductase TM_1169 0.0098
4443 Quinate/shikimate dehydrogenase ydiB 0.0098
4449 ADP-ribosyltransferase Not Available 0.0098
4414 Dehydrogenase TT_P0035 0.0098
4507 Alanine dehydrogenase ald 0.0098
4446 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase Not Available 0.0098
4472 Glucose 1-dehydrogenase Not Available 0.0098
4423 Levodione reductase lvr 0.0098
3735 NAD(P) transhydrogenase subunit alpha part 1 pntAA 0.0098
4336 Glyceraldehyde 3-phosphate dehydrogenase Not Available 0.0098
4436 Glyceraldehyde 3-phosphate dehydrogenase tthHB8IM 0.0098
4505 Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase bphB 0.0098
2350 3-isopropylmalate dehydrogenase leuB 0.0098
3092 3-isopropylmalate dehydrogenase leuB 0.0098
4487 Transcriptional regulator nadR nadR 0.0098
3381 Alcohol dehydrogenase Not Available 0.0098
4508 Alcohol dehydrogenase adhA 0.0098
4448 L-2-hydroxyisocaproate dehydrogenase Not Available 0.0098
4428 Redox-sensing transcriptional repressor rex rex 0.0098
4451 Vip2Ac vip2Ac 0.0098
4447 Hypothetical protein yhfP yhfP 0.0098
4506 Myo-inositol-1-phosphate synthase-related protein TM_1419 0.0098
4455 Glycerol dehydrogenase gldA 0.0098
4466 Glutathione-independent formaldehyde dehydrogenase fdhA 0.0098
4418 AGR_L_3209p AGR_L_3209 0.0098
4502 Formate dehydrogenase Not Available 0.0098
4497 Benzyl alcohol dehydrogenase xylB 0.0097
4456 Inorganic polyphosphate/ATP-NAD kinase ppnK 0.0097
3729 Citrate synthase gltA 0.0097
4575 Citrate synthase cit 0.0097
4580 Citrate synthase gltA 0.0097
4475 Hypothetical protein Rv0046c/MT0052 ino1 0.0097
4435 L-aspartate dehydrogenase nadX 0.0097
4471 CDP-D-glucose-4,6-dehydratase ascB 0.0097
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0096
816 Biliverdin reductase A BLVRA 0.0096
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0096
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0096
2567 Thymidylate synthase thyX thyX 0.0093
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0093
2823 Trypanothione reductase TPR 0.0093
126 D-lactate dehydrogenase dld 0.0092
3545 D-lactate dehydrogenase Not Available 0.0092
4510 D-lactate dehydrogenase ldhA 0.0092
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.0092
646 Malate dehydrogenase, cytoplasmic MDH1 0.0092
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.0092
328 Sorbitol dehydrogenase SORD 0.0091
597 Dihydropteridine reductase QDPR 0.0091
396 Alcohol dehydrogenase 4 ADH4 0.0091
4954 Soluble cytochrome b558 Not Available 0.009
4934 Cytochrome c-551 nirM 0.009
5218 Cytochrome c-551 nirM 0.009
4943 Cytochrome c6 petJ 0.009
4925 Cytochrome c-type protein SHP shp 0.009
4984 Neuroglobin NGB 0.009
4961 Hemophore HasA hasA 0.009
4936 Cytochrome c2 iso-2 Not Available 0.009
3116 Bacterioferritin bfr 0.009
4906 Bacterioferritin bfr 0.009
4965 Bacterioferritin bfr 0.009
4915 Cytochrome c-550 psbV 0.009
4959 Cytochrome c-550 psbV 0.009
5216 Cytochrome c-550 psbV 0.009
4998 Hemoglobin-like protein yjbI yjbI 0.009
4947 Bacterial hemoglobin vhb 0.009
4905 Cytochrome c2 Not Available 0.009
4939 Cytochrome c2 cycA 0.009
4964 Cytochrome c2 cycA 0.009
4979 Cytochrome c2 cycA 0.009
6673 Cytochrome c2 cycA 0.009
4935 Cytochrome c-554 cycA1 0.009
4910 Cytoglobin CYGB 0.009
4942 Diheme cytochrome c napB napB 0.009
4907 Cytochrome c-L moxG 0.009
6865 Cytochrome c-L moxG 0.009
4975 Cytochrome c-556 RPA3973 0.009
4971 Nonaheme cytochrome c hmcA 0.009
4916 Cyanoglobin glbN 0.009
4909 CooA protein cooA 0.009
4994 Hemoglobin-like protein HbO glbO 0.009
5000 HemO hemO 0.009
4960 Putative cytochrome P450-family protein SCO7417 0.009
4999 Cytochrome P450 165B3 CYP165B3 0.009
4981 Iron-starvation protein PigA pigA 0.009
4937 Cytochrome oxidase subunit II rcoxA 0.009
4989 Cytochrome c551 peroxidase ccp 0.009
5222 Cytochrome c551 peroxidase ccpA 0.009
4922 Cytochrome c, putative SO_4144 0.009
4976 Apocytochrome f petA 0.009
6407 Apocytochrome f petA 0.009
4904 Cytochrome c family protein GSU1996 0.009
4952 Catalase/peroxidase katA 0.009
4903 Methyl-accepting chemotaxis protein Tar4 0.009
4764 Cytochrome P450 165C4 CYP165C4 0.009
4931 Cytochrome P450 167A1 CYP167A1 0.009
4926 Heme-based aerotactic transducer hemAT hemAT 0.009
4993 Hydroxylamine oxidoreductase hao1 0.009
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.009
4972 P450cin cinA 0.009
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.009
3093 Catalase HPII katE 0.009
2769 P-hydroxybenzoate hydroxylase pobA 0.0089
2809 P-hydroxybenzoate hydroxylase pobA 0.0089
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.0088
77 L-lactate dehydrogenase B chain LDHB 0.0088
12 Alcohol dehydrogenase class 3 ADH5 0.0088
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0085
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0085
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0085
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0085
2380 Monomeric sarcosine oxidase soxA 0.0085
473 L-lactate dehydrogenase A chain LDHA 0.0085
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0085
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0085
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0085
4427 TDP-glucose-4,6-dehydratase desIV 0.0084
3598 dTDP-4-dehydrorhamnose reductase rfbD 0.0084
3177 dTDP-glucose 4,6-dehydratase rfbB 0.0084
4499 dTDP-glucose 4,6-dehydratase rmlB 0.0084
2967 CDP-paratose 2-epimerase rfbE 0.0084
4503 NADPH-flavin oxidoreductase frp 0.0084
4482 UDP-galactose 4-epimerase galE 0.0084
2424 L-lactate dehydrogenase ldh 0.0084
2641 L-lactate dehydrogenase Not Available 0.0084
4437 L-lactate dehydrogenase ldh 0.0084
4442 L-lactate dehydrogenase ldh 0.0084
2507 Diphtheria toxin Not Available 0.0084
2538 6-phospho-beta-glucosidase bglT bglT 0.0084
2393 Maltose-6'-phosphate glucosidase glvA 0.0084
4509 Acetoin(diacetyl) reductase budC 0.0084
2831 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase Not Available 0.0084
3059 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase fabG3 0.0084
3081 3-dehydroquinate synthase aroB 0.0084
3615 Dihydrodipicolinate reductase dapB 0.0084
3618 Dihydrodipicolinate reductase dapB 0.0084
4462 Dihydrodipicolinate reductase dapB 0.0084
6698 Dehydrogenase/reductase SDR family member 4-like 2 DHRS4L2 0.0084
2591 Urocanate hydratase hutU 0.0084
3671 7-alpha-hydroxysteroid dehydrogenase hdhA 0.0084
3401 D-2-hydroxyisocaproate dehydrogenase Not Available 0.0084
1199 GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 ART1 0.0084
4450 Iota toxin component Ia Not Available 0.0084
2018 Deoxyhypusine synthase DHPS 0.0084
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0084
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0084
4498 Ornithine cyclodeaminase PP3533 0.0084
4496 C-terminal-binding protein 1 CTBP1 0.0084
2881 Gamma-aminobutyraldehyde dehydrogenase prr 0.0084
2336 2,3-diketo-L-gulonate reductase dlgD 0.0084
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0084
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0082
6645 D-amino-acid oxidase DAO 0.0081
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0081
4504 WbpP Not Available 0.0078
2683 Mono-ADP-ribosyltransferase C3 C3 0.0078
3296 Nicotinamide mononucleotide adenylyltransferase 1 NMNAT1 0.0078
3367 GDP-mannose 6-dehydrogenase algD 0.0078
4318 Siroheme synthase cysG 0.0077
569 Retinal dehydrogenase 2 ALDH1A2 0.0077
4343 Alpha-glucosidase aglA 0.0077
3736 Glyceraldehyde-3-phosphate dehydrogenase A gapA 0.0077
2799 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal Not Available 0.0077
611 Retinal dehydrogenase 1 ALDH1A1 0.0077
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0076
4948 Cytochrome c-553 Not Available 0.0076
4923 Cytochrome c3 DvMF_2499 0.0076
4945 Cytochrome c3 Not Available 0.0076
4949 Cytochrome c3 DVU_3171 0.0076
4968 Cytochrome c3 cytc3 0.0076
4997 Cytochrome c3 SO_2727 0.0076
5219 Cytochrome c3 cyd 0.0076
4920 Peroxidase/catalase katG 0.0076
4988 Sulfite oxidase, mitochondrial SUOX 0.0076
4385 Cytochrome c' Not Available 0.0076
4967 Cytochrome c' cycA 0.0076
5038 Cytochrome c' Not Available 0.0076
5223 Cytochrome c' cycP 0.0076
4902 Nine-heme cytochrome c Ddes_2038 0.0076
3189 High-molecular-weight cytochrome c hmcA 0.0076
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0076
4037 Hypothetical protein GPX1 0.0076
4297 Hypothetical protein SP_1951 0.0076
4521 Hypothetical protein BC_2969 0.0076
4540 Hypothetical protein TM_1070 0.0076
4555 Hypothetical protein MT1739 0.0076
4569 Hypothetical protein mshD 0.0076
4578 Hypothetical protein PA3270 0.0076
4747 Hypothetical protein PA3967 0.0076
5177 Hypothetical protein TM_0096 0.0076
5194 Hypothetical protein PA1204 0.0076
5240 Hypothetical protein Rv2991 0.0076
5370 Hypothetical protein TM_1158 0.0076
5710 Hypothetical protein Tb927.5.1360 0.0076
4990 PpcA ppcA 0.0076
2119 Cytochrome b5 CYB5A 0.0076
3570 Cytochrome P450 152A1 cypC 0.0076
2915 Sensor protein fixL fixL 0.0076
4944 Sensor protein fixL fixL 0.0076
3375 Acidic cytochrome c3 Not Available 0.0076
4813 Heme oxygenase hmuO 0.0076
5769 Heme oxygenase Not Available 0.0076
4992 Cytochrome c peroxidase Not Available 0.0076
4289 Cytochrome P450 TT_P0059 0.0076
6262 Cytochrome P450 staP 0.0076
251 Alcohol dehydrogenase 1A ADH1A 0.0075
4476 Mannitol dehydrogenase mtlD 0.0075
63 Malate dehydrogenase mdh 0.0075
3445 Malate dehydrogenase mdh 0.0075
4420 Malate dehydrogenase mdh 0.0075
4438 Malate dehydrogenase mdh 0.0075
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0075
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0074
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.0073
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.0073
3333 Nicotinamide mononucleotide adenylyltransferase 3 NMNAT3 0.0073
2434 NH(3)-dependent NAD(+) synthetase nadE 0.0073
2910 NH(3)-dependent NAD(+) synthetase nadE 0.0073
3217 NH(3)-dependent NAD(+) synthetase nadE 0.0073
2826 Glucose--fructose oxidoreductase gfo 0.0073
3070 Adenosylhomocysteinase AHCY 0.0073
4424 Adenosylhomocysteinase PFE1050w 0.0073
6278 Adenosylhomocysteinase ahcY 0.0073
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.0073
3191 Histidinol dehydrogenase hisD 0.0073
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0073
444 Alcohol dehydrogenase 1B ADH1B 0.0072
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.007
3670 Soluble cytochrome b562 precursor cybC 0.007
3291 Cytochrome c-552 cycA 0.007
4927 Cytochrome c-552 nrfA 0.007
4938 Cytochrome c-552 cycA 0.007
4953 Cytochrome c-552 nrfA 0.007
5217 Cytochrome c-552 cycM 0.007
3411 Cytochrome P450 121 cyp121 0.007
4386 Hemoglobin-like protein HbN glbN 0.007
2617 Nitric oxide synthase oxygenase nos 0.007
2701 Nitric oxide synthase oxygenase nos 0.007
2286 Isocitrate dehydrogenase [NADP] icd 0.0067
2302 Isocitrate dehydrogenase [NADP] icd 0.0067
2771 Isocitrate dehydrogenase [NADP] icd 0.0067
4491 DNA ligase, NAD-dependent ligA 0.0067
810 Heme oxygenase 1 HMOX1 0.0067
3391 Heme oxygenase 1 pbsA1 0.0067
2230 Catalase CAT 0.0066
3249 Catalase katA 0.0066
3625 Catalase katA 0.0066
4539 Catalase katA 0.0066
4941 Catalase katB 0.0066
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0066
2762 UDP-glucose 4-epimerase GALE 0.0065
3461 UDP-glucose 4-epimerase galE 0.0065
3127 Nitrite reductase nirS 0.0065
3284 Nitrite reductase nirS 0.0065
3221 Cytochrome c4 cc4 0.0065
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0065
517 Alcohol dehydrogenase 1C ADH1C 0.0064
3947 Xanthine dehydrogenase/oxidase XDH 0.0063
4608 Putative cytochrome P450 SCO1207 0.0062
4963 Putative cytochrome P450 SCO2884 0.0062
6254 Putative cytochrome P450 SCO6998 0.0062
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0062
4120 NADPH--cytochrome P450 reductase POR 0.0061
2972 6-deoxyerythronolide B hydroxylase eryF 0.0061
260 Cytochrome P450 51 ERG11 0.0058
761 Cytochrome P450 51 ERG11 0.0058
3163 Cytochrome P450 51 cyp51 0.0058
518 Peroxidase/catalase T katG 0.0057
1507 Cytochrome c CYCS 0.0056
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0055
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0055
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0055
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0055
693 Hemoglobin subunit beta HBB 0.0055
6268 Hydroxyacid oxidase 1 HAO1 0.0054
3939 Amine oxidase [flavin-containing] B MAOB 0.0051
358 Cystathionine beta-synthase CBS 0.005
3941 Amine oxidase [flavin-containing] A MAOA 0.0048
2298 Cytochrome P450-cam camC 0.0047
7 Nitric oxide synthase, inducible NOS2 0.004
275 Arachidonate 5-lipoxygenase ALOX5 0.0039
291 Nitric-oxide synthase, endothelial NOS3 0.0039
6106 Cytochrome P450 2C18 CYP2C18 0.0033
290 Prostaglandin G/H synthase 2 PTGS2 0.0029
20 Prostaglandin G/H synthase 1 PTGS1 0.0027
587 Serum albumin ALB 0.0026
6030 Cytochrome P450 2B6 CYP2B6 0.0025
4924 Cytochrome P450 2C8 CYP2C8 0.0023
4757 Cytochrome P450 2C9 CYP2C9 0.0021
666 NADP-dependent malic enzyme ME1 0.0021
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.002
755 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NDUFA3 0.002
475 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NDUFB2 0.002
343 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NDUFC1 0.002
300 NADH-ubiquinone oxidoreductase chain 4L MT-ND4L 0.002
190 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 NDUFA4 0.002
374 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NDUFB1 0.002
30 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NDUFV3 0.002
525 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NDUFA5 0.002
219 NADH-ubiquinone oxidoreductase chain 3 MT-ND3 0.002
104 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NDUFS6 0.002
247 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUFA1 0.002
417 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NDUFB6 0.002
324 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NDUFB4 0.002
582 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NDUFA13 0.002
353 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 NDUFA4L2 0.002
829 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NDUFA12 0.002
602 Acyl carrier protein, mitochondrial NDUFAB1 0.002
405 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NDUFA8 0.002
272 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NDUFB10 0.002
313 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NDUFB3 0.002
384 NADH-ubiquinone oxidoreductase chain 6 MT-ND6 0.002
607 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NDUFA2 0.002
555 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 0.002
598 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NDUFA11 0.002
656 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 0.002
91 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NDUFA10 0.002
99 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NDUFS5 0.002
107 C-4 methylsterol oxidase SC4MOL 0.002
270 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NDUFB5 0.002
372 Estradiol 17-beta-dehydrogenase 3 HSD17B3 0.002
446 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NDUFA7 0.002
644 Heme oxygenase 2 HMOX2 0.002
4982 Heme oxygenase 2 pbsA2 0.002
41 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NDUFS8 0.002
236 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NDUFA6 0.002
746 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NDUFB8 0.002
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.002
3726 D-3-phosphoglycerate dehydrogenase serA 0.002
4291 D-3-phosphoglycerate dehydrogenase serA 0.002
50 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating NSDHL 0.002
568 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NDUFB7 0.002
152 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NDUFV2 0.002
145 Corticosteroid 11-beta-dehydrogenase isozyme 2 HSD11B2 0.002
609 15-hydroxyprostaglandin dehydrogenase [NAD+] HPGD 0.002
539 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NDUFV1 0.002
729 GDP-L-fucose synthetase TSTA3 0.002
3463 GDP-L-fucose synthetase fcl 0.002
487 Aldo-keto reductase family 1 member C4 AKR1C4 0.002
167 L-lactate dehydrogenase C chain LDHC 0.002
326 L-lactate dehydrogenase A-like 6A LDHAL6A 0.002
206 3-keto-steroid reductase HSD17B7 0.002
196 D-beta-hydroxybutyrate dehydrogenase, mitochondrial BDH1 0.002
608 NADH-ubiquinone oxidoreductase chain 4 MT-ND4 0.002
14 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial IDH3A 0.002
335 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NDUFA9 0.002
112 L-lactate dehydrogenase A-like 6B LDHAL6B 0.002
216 Aldehyde dehydrogenase 3B2 ALDH3B2 0.002
616 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial IDH3B 0.002
9 Estradiol 17-beta-dehydrogenase 2 HSD17B2 0.002
671 Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial PDHA2 0.002
628 Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial PDHA1 0.002
848 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial IDH3G 0.002
496 Aldehyde dehydrogenase 3B1 ALDH3B1 0.002
34 7-dehydrocholesterol reductase DHCR7 0.002
662 Fatty aldehyde dehydrogenase ALDH3A2 0.002
288 Trifunctional enzyme subunit alpha, mitochondrial HADHA 0.002
711 UDP-glucose 6-dehydrogenase UGDH 0.002
3672 UDP-glucose 6-dehydrogenase hasB 0.002
149 Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 0.002
531 Aldehyde dehydrogenase X, mitochondrial ALDH1B1 0.002
258 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial ALDH6A1 0.002
271 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial ALDH4A1 0.002
141 3-hydroxyisobutyrate dehydrogenase, mitochondrial HIBADH 0.002
637 NADH-ubiquinone oxidoreductase chain 5 MT-ND5 0.002
721 NADH-ubiquinone oxidoreductase chain 2 MT-ND2 0.002
231 Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic GPD1 0.002
643 Peroxisomal bifunctional enzyme EHHADH 0.002
548 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NDUFS1 0.002
393 GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase H6PD 0.002
857 Malate dehydrogenase, mitochondrial MDH2 0.002
11 NAD(P) transhydrogenase, mitochondrial NNT 0.002
74 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial DLAT 0.0019
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0017
110 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.0017
626 Cysteine dioxygenase type 1 CDO1 0.0017
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0017
248 Pyrroline-5-carboxylate reductase 1 PYCR1 0.0017
802 Pyrroline-5-carboxylate reductase 2 PYCR2 0.0017
13 Aminomethyltransferase, mitochondrial AMT 0.0017
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0017
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0017
296 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial MTHFD2 0.0017
6026 Alcohol dehydrogenase 6 ADH6 0.0017
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0017
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0017
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0017
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0017
627 11-cis retinol dehydrogenase RDH5 0.0017
640 Aldehyde dehydrogenase 1A3 ALDH1A3 0.0017
654 Flavin reductase BLVRB 0.0016
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0016
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0016
57 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I HSD3B1 0.0015
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0015
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0015
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0015
279 Tyrosinase TYR 0.0015
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0014
380 Cytochrome P450 17A1 CYP17A1 0.0014
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0013
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0013
822 Aldose reductase AKR1B1 0.0013
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0013
365 Dihydrofolate reductase DHFR 0.0012
2381 Dihydrofolate reductase DFR1 0.0012
2833 Dihydrofolate reductase Not Available 0.0012
2931 Dihydrofolate reductase folA 0.0012
3544 Dihydrofolate reductase folA 0.0012
3682 Dihydrofolate reductase folA 0.0012
6642 Dihydrofolate reductase folA 0.0012
6756 Dihydrofolate reductase dfrA 0.0012
468 Cytochrome P450 4A11 CYP4A11 0.0012
6020 Aldehyde oxidase AOX1 0.0011
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