DT-Web

DB02115 - Daidzin


Identification
Name Daidzin
Accession Number DB02115 (EXPT01311)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 416.3781
Groups experimental
Monoisotopic Weight 416.110732238
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Aldehyde dehydrogenase, mitochondrial
Name Aldehyde dehydrogenase, mitochondrial
Gene Name ALDH2
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.4873

Transporters


ATP-binding cassette sub-family G member 2
Name ATP-binding cassette sub-family G member 2
Gene Name ABCG2
Actions inhibitor
References
  • Perez M, Real R, Mendoza G, Merino G, Prieto JG, Alvarez AI: Milk secretion of nitrofurantoin, as a specific BCRP/ABCG2 substrate, in assaf sheep: modulation by isoflavones. J Vet Pharmacol Ther. 2009 Oct;32(5):498-502. - Pubmed
DTHybrid score 0.1905

Predictions


Id Partner name Gene Name Score
613 Atrial natriuretic peptide receptor A NPR1 0.1365
4512 Cytochrome P450 3A4 CYP3A4 0.0636
1588 Multidrug resistance protein 1 ABCB1 0.0593
4200 Cytochrome P450 1A2 CYP1A2 0.0451
4757 Cytochrome P450 2C9 CYP2C9 0.0369
4118 Cytochrome P450 3A5 CYP3A5 0.0342
6030 Cytochrome P450 2B6 CYP2B6 0.0338
6068 Guanylate cyclase soluble subunit alpha-2 GUCY1A2 0.0316
4924 Cytochrome P450 2C8 CYP2C8 0.0315
6013 Cytochrome P450 2E1 CYP2E1 0.0285
862 Multidrug resistance-associated protein 1 ABCC1 0.0271
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0257
6016 Cytochrome P450 2C19 CYP2C19 0.0243
6024 Cytochrome P450 1A1 CYP1A1 0.0242
4119 Cytochrome P450 2D6 CYP2D6 0.0232
153 Dopamine beta-hydroxylase DBH 0.0223
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0217
5126 Arginase rocF 0.0151
587 Serum albumin ALB 0.0142
740 Argininosuccinate synthase ASS1 0.0141
865 Argininosuccinate synthase ASS1 0.0141
2680 Argininosuccinate synthase argG 0.0141
3194 Argininosuccinate synthase argG 0.0141
1898 Cytochrome P450 1B1 CYP1B1 0.014
6145 Solute carrier family 22 member 1 SLC22A1 0.014
6147 Solute carrier family 22 member 3 SLC22A3 0.014
6142 Solute carrier family 22 member 8 SLC22A8 0.0137
1353 DNA topoisomerase 1 TOP1 0.0135
3552 DNA topoisomerase 1 topA 0.0135
6144 Solute carrier family 22 member 2 SLC22A2 0.0135
844 Epidermal growth factor receptor EGFR 0.0134
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0134
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0127
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0124
624 Guanidinoacetate N-methyltransferase GAMT 0.0122
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0122
6107 Cytochrome P450 3A7 CYP3A7 0.0122
776 Bile salt export pump ABCB11 0.0121
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0114
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0105
6137 Multidrug resistance-associated protein 6 ABCC6 0.0103
118 Organic cation/carnitine transporter 2 SLC22A5 0.0099
504 Mast/stem cell growth factor receptor KIT 0.0098
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0093
6148 Multidrug resistance-associated protein 7 ABCC10 0.0092
117 Sterol O-acyltransferase 1 SOAT1 0.009
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.009
5682 Ribonuclease pancreatic RNASE1 0.0088
817 DNA topoisomerase 2-alpha TOP2A 0.0088
833 Organic cation/carnitine transporter 1 SLC22A4 0.0087
1729 Solute carrier family 22 member 6 SLC22A6 0.0087
2300 Lysozyme E 0.0086
3633 Lysozyme R 0.0086
5597 Lysozyme 17 0.0086
2164 Multidrug resistance-associated protein 4 ABCC4 0.0084
33 Cystine/glutamate transporter SLC7A11 0.0084
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0076
603 DNA polymerase alpha catalytic subunit POLA1 0.0074
4773 Deoxycytidine kinase DCK 0.0074
259 Microsomal triglyceride transfer protein large subunit MTTP 0.0072
6599 HTH-type transcriptional regulator ttgR ttgR 0.0071
360 Ribonucleoside-diphosphate reductase large subunit RRM1 0.007
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.007
228 Beta platelet-derived growth factor receptor PDGFRB 0.007
102 DNA topoisomerase I, mitochondrial TOP1MT 0.007
992 Protein tyrosine kinase 2 beta PTK2B 0.0067
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0063
176 30S ribosomal protein S10 rpsJ 0.006
6175 30S ribosomal protein S10 rpsJ 0.006
4117 Probable pyruvate-flavodoxin oxidoreductase ydbK 0.006
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0059
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0059
4120 NADPH--cytochrome P450 reductase POR 0.0058
1024 Solute carrier family 22 member 11 SLC22A11 0.0058
5718 Cytochrome P450 2A6 CYP2A6 0.0057
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0057
685 Oxygen-insensitive NADPH nitroreductase nfsA 0.0057
6945 Oxygen-insensitive NADPH nitroreductase rdxA 0.0057
26 Vascular endothelial growth factor receptor 3 FLT4 0.0053
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0053
887 DNA gyrase subunit B gyrB 0.0051
4150 DNA gyrase subunit B gyrB 0.0051
6225 DNA gyrase subunit B gyrB 0.0051
32 Vascular endothelial growth factor receptor 1 FLT1 0.0051
407 Vascular endothelial growth factor receptor 2 KDR 0.0051
6143 Solute carrier family 22 member 7 SLC22A7 0.0051
468 Cytochrome P450 4A11 CYP4A11 0.005
136 Estrogen receptor ESR1 0.005
1650 Heme carrier protein 1 SLC46A1 0.005
5787 Angiopoietin-1 receptor TEK 0.0049
20 Prostaglandin G/H synthase 1 PTGS1 0.0049
908 Glutathione S-transferase theta-1 GSTT1 0.0049
29 Tubulin beta-1 chain TUBB1 0.0049
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0048
2539 Tubulin alpha-1 chain TUBA4A 0.0045
3947 Xanthine dehydrogenase/oxidase XDH 0.0043
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0043
6141 Sodium/bile acid cotransporter SLC10A1 0.0043
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0043
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0042
869 Estrogen receptor beta ESR2 0.0042
6163 Copper-transporting ATPase 2 ATP7B 0.0041
6165 Copper-transporting ATPase 1 ATP7A 0.0041
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0041
904 Glutathione S-transferase P GSTP1 0.004
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.004
165 FL cytokine receptor FLT3 0.004
6146 High affinity copper uptake protein 1 SLC31A1 0.004
6220 Aryl hydrocarbon receptor AHR 0.0039
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0039
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0039
6106 Cytochrome P450 2C18 CYP2C18 0.0038
3811 Cytochrome P450 19A1 CYP19A1 0.0037
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0036
731 HIV-1 protease HIV-1 protease 0.0036
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0035
896 Glutathione S-transferase Mu 1 GSTM1 0.0035
3917 Methylenetetrahydrofolate reductase MTHFR 0.0034
3856 Fibroblast growth factor receptor 3 FGFR3 0.0033
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0033
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0032
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0032
70 Type-1 angiotensin II receptor AGTR1 0.0032
461 Glycine receptor subunit alpha-3 GLRA3 0.0032
293 Gamma-glutamyl hydrolase GGH 0.0031
1757 Myeloperoxidase MPO 0.0031
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0031
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.003
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.003
738 Monocarboxylate transporter 1 SLC16A1 0.003
756 Sex hormone-binding globulin SHBG 0.003
5923 Microtubule-associated protein tau MAPT 0.003
5924 Microtubule-associated protein 4 MAP4 0.003
469 Annexin A1 ANXA1 0.003
3950 Cell division protein kinase 9 CDK9 0.0029
3968 Cell division protein kinase 8 CDK8 0.0029
78 Acetyl-CoA acetyltransferase, mitochondrial ACAT1 0.0028
1852 Microtubule-associated protein 2 MAP2 0.0028
4604 Liver carboxylesterase 1 CES1 0.0027
6136 Multidrug resistance-associated protein 5 ABCC5 0.0027
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0027
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0027
816 Biliverdin reductase A BLVRA 0.0027
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0027
106 Cannabinoid receptor 2 CNR2 0.0027
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0027
373 Transthyretin TTR 0.0027
273 Apoptosis regulator Bcl-2 BCL2 0.0026
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0026
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0026
68 Cannabinoid receptor 1 CNR1 0.0026
4192 DNA topoisomerase 2-beta TOP2B 0.0026
890 Niemann-Pick C1-like protein 1 NPC1L1 0.0026
804 Mitochondrial folate transporter/carrier SLC25A32 0.0026
718 Folate receptor gamma FOLR3 0.0026
299 Folate receptor beta FOLR2 0.0026
290 Prostaglandin G/H synthase 2 PTGS2 0.0026
936 Ephrin type-A receptor 2 EPHA2 0.0026
3959 Cell division protein kinase 4 CDK4 0.0025
511 5-hydroxytryptamine 1F receptor HTR1F 0.0025
3482 Cell division protein kinase 7 CDK7 0.0025
183 Vascular endothelial growth factor A VEGFA 0.0024
646 Malate dehydrogenase, cytoplasmic MDH1 0.0024
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.0024
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0024
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0024
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.0024
597 Dihydropteridine reductase QDPR 0.0024
396 Alcohol dehydrogenase 4 ADH4 0.0024
328 Sorbitol dehydrogenase SORD 0.0024
363 NADP-dependent malic enzyme, mitochondrial ME3 0.0024
1760 Aminopeptidase N ANPEP 0.0024
6843 Aminopeptidase N pepN 0.0024
3941 Amine oxidase [flavin-containing] A MAOA 0.0023
3955 Cell division protein kinase 6 CDK6 0.0023
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0023
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.0023
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.0023
12 Alcohol dehydrogenase class 3 ADH5 0.0023
77 L-lactate dehydrogenase B chain LDHB 0.0022
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0022
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0022
823 Fibroblast growth factor receptor 2 FGFR2 0.0022
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0022
6111 DNA polymerase epsilon subunit 4 POLE4 0.0022
6112 DNA polymerase epsilon subunit 3 POLE3 0.0022
6110 DNA polymerase epsilon subunit 2 POLE2 0.0022
6108 Ribonucleoside-diphosphate reductase subunit M2 B RRM2B 0.0022
6109 DNA polymerase epsilon catalytic subunit A POLE 0.0022
569 Retinal dehydrogenase 2 ALDH1A2 0.0022
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0022
6182 Cytochrome P450 2J2 CYP2J2 0.0022
3810 Catechol O-methyltransferase COMT 0.0022
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0022
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0022
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0022
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0022
473 L-lactate dehydrogenase A chain LDHA 0.0021
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0021
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0021
611 Retinal dehydrogenase 1 ALDH1A1 0.0021
1618 High affinity nerve growth factor receptor NTRK1 0.0021
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0021
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0021
166 NAD-dependent malic enzyme, mitochondrial ME2 0.002
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.002
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.002
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.002
1742 D-HSCDK2 CDK2deltaT 0.002
1771 Cell division control protein 2 homolog CDK1 0.002
3321 Cell division control protein 2 homolog CRK2 0.002
4218 Ribonucleoside-diphosphate reductase M2 subunit RRM2 0.002
1058 Cell division protein kinase 5 CDK5 0.002
251 Alcohol dehydrogenase 1A ADH1A 0.0019
4423 Levodione reductase lvr 0.0019
4456 Inorganic polyphosphate/ATP-NAD kinase ppnK 0.0019
4428 Redox-sensing transcriptional repressor rex rex 0.0019
4447 Hypothetical protein yhfP yhfP 0.0019
4449 ADP-ribosyltransferase Not Available 0.0019
4475 Hypothetical protein Rv0046c/MT0052 ino1 0.0019
4455 Glycerol dehydrogenase gldA 0.0019
4495 3-oxoacyl-(Acyl carrier protein) reductase TM_1169 0.0019
4435 L-aspartate dehydrogenase nadX 0.0019
4466 Glutathione-independent formaldehyde dehydrogenase fdhA 0.0019
4446 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase Not Available 0.0019
4487 Transcriptional regulator nadR nadR 0.0019
4505 Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase bphB 0.0019
3735 NAD(P) transhydrogenase subunit alpha part 1 pntAA 0.0019
4500 L-lactate dehydrogenase 2 ldh2 0.0019
4336 Glyceraldehyde 3-phosphate dehydrogenase Not Available 0.0019
4436 Glyceraldehyde 3-phosphate dehydrogenase tthHB8IM 0.0019
3381 Alcohol dehydrogenase Not Available 0.0019
4508 Alcohol dehydrogenase adhA 0.0019
4414 Dehydrogenase TT_P0035 0.0019
2350 3-isopropylmalate dehydrogenase leuB 0.0019
3092 3-isopropylmalate dehydrogenase leuB 0.0019
4471 CDP-D-glucose-4,6-dehydratase ascB 0.0019
4418 AGR_L_3209p AGR_L_3209 0.0019
4507 Alanine dehydrogenase ald 0.0019
4443 Quinate/shikimate dehydrogenase ydiB 0.0019
4497 Benzyl alcohol dehydrogenase xylB 0.0019
4506 Myo-inositol-1-phosphate synthase-related protein TM_1419 0.0019
4502 Formate dehydrogenase Not Available 0.0019
3729 Citrate synthase gltA 0.0019
4575 Citrate synthase cit 0.0019
4580 Citrate synthase gltA 0.0019
4451 Vip2Ac vip2Ac 0.0019
4472 Glucose 1-dehydrogenase Not Available 0.0019
4467 Alpha-glucosidase, putative TM_0752 0.0019
4448 L-2-hydroxyisocaproate dehydrogenase Not Available 0.0019
6166 Organic solute transporter subunit alpha OSTA 0.0019
6167 Organic solute transporter subunit beta OSTB 0.0019
824 Sodium-dependent serotonin transporter SLC6A4 0.0019
6837 Serine/threonine-protein kinase 17B STK17B 0.0018
6836 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial HIBCH 0.0018
725 5-hydroxytryptamine 1D receptor HTR1D 0.0018
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0018
885 5-hydroxytryptamine 1B receptor HTR1B 0.0018
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0018
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0018
871 Glucocorticoid receptor NR3C1 0.0018
444 Alcohol dehydrogenase 1B ADH1B 0.0018
3809 Estrogen-related receptor gamma ESRRG 0.0018
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0018
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0017
275 Arachidonate 5-lipoxygenase ALOX5 0.0017
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0017
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0017
2216 Fibroblast growth factor receptor 4 FGFR4 0.0017
6228 Nuclear receptor coactivator 1 NCOA1 0.0017
4217 Telomerase reverse transcriptase TERT 0.0017
1063 Signal transducer and activator of transcription 5B STAT5B 0.0017
935 Proto-oncogene tyrosine-protein kinase Yes YES1 0.0017
6241 Nuclear receptor coactivator 2 NCOA2 0.0017
239 Coagulation factor X F10 0.0017
4226 Uridine phosphorylase 2 UPP2 0.0017
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0017
342 P protein [Includes: DNA-directed DNA polymerase P 0.0017
612 P protein [Includes: DNA-directed DNA polymerase P 0.0017
714 Glutathione reductase, mitochondrial GSR 0.0017
161 Tubulin beta chain TUBB 0.0016
312 Tubulin beta chain TUB2 0.0016
380 Cytochrome P450 17A1 CYP17A1 0.0016
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0016
320 5-hydroxytryptamine 1A receptor HTR1A 0.0016
677 Choline-phosphate cytidylyltransferase A PCYT1A 0.0016
6656 UDP-glucuronosyltransferase 3A1 UGT3A1 0.0016
24 Thymidylate synthase TMP1 0.0016
359 Thymidylate synthase TYMS 0.0016
2626 Thymidylate synthase thyA 0.0016
2729 Thymidylate synthase thyA 0.0016
5352 Thymidylate synthase THYA 0.0016
4225 Uridine phosphorylase 1 UPP1 0.0016
713 Sodium-dependent dopamine transporter SLC6A3 0.0016
517 Alcohol dehydrogenase 1C ADH1C 0.0015
934 Proto-oncogene tyrosine-protein kinase Fyn FYN 0.0015
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0015
6171 Solute carrier family 28 member 3 SLC28A3 0.0015
702 UMP-CMP kinase CMPK1 0.0015
5626 Nucleoside diphosphate kinase B NME2 0.0015
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0015
4486 Phenol 2-hydroxylase component B pheA2 0.0015
6031 Cytochrome P450 3A43 CYP3A43 0.0015
4439 Ferredoxin reductase bphA4 0.0015
4477 Dihydrolipoyl dehydrogenase lpdV 0.0015
5077 Dihydrolipoyl dehydrogenase Not Available 0.0015
5117 Dihydrolipoyl dehydrogenase lpd 0.0015
3598 dTDP-4-dehydrorhamnose reductase rfbD 0.0015
4427 TDP-glucose-4,6-dehydratase desIV 0.0015
3177 dTDP-glucose 4,6-dehydratase rfbB 0.0015
4499 dTDP-glucose 4,6-dehydratase rmlB 0.0015
4503 NADPH-flavin oxidoreductase frp 0.0015
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0015
4482 UDP-galactose 4-epimerase galE 0.0015
2967 CDP-paratose 2-epimerase rfbE 0.0015
2507 Diphtheria toxin Not Available 0.0015
2538 6-phospho-beta-glucosidase bglT bglT 0.0015
2393 Maltose-6'-phosphate glucosidase glvA 0.0015
2018 Deoxyhypusine synthase DHPS 0.0015
4509 Acetoin(diacetyl) reductase budC 0.0015
3671 7-alpha-hydroxysteroid dehydrogenase hdhA 0.0015
2881 Gamma-aminobutyraldehyde dehydrogenase prr 0.0015
3401 D-2-hydroxyisocaproate dehydrogenase Not Available 0.0015
3081 3-dehydroquinate synthase aroB 0.0015
126 D-lactate dehydrogenase dld 0.0015
3545 D-lactate dehydrogenase Not Available 0.0015
4510 D-lactate dehydrogenase ldhA 0.0015
2591 Urocanate hydratase hutU 0.0015
3615 Dihydrodipicolinate reductase dapB 0.0015
3618 Dihydrodipicolinate reductase dapB 0.0015
4462 Dihydrodipicolinate reductase dapB 0.0015
4498 Ornithine cyclodeaminase PP3533 0.0015
2831 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase Not Available 0.0015
3059 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase fabG3 0.0015
2424 L-lactate dehydrogenase ldh 0.0015
2641 L-lactate dehydrogenase Not Available 0.0015
4437 L-lactate dehydrogenase ldh 0.0015
4442 L-lactate dehydrogenase ldh 0.0015
1199 GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 ART1 0.0015
4450 Iota toxin component Ia Not Available 0.0015
6698 Dehydrogenase/reductase SDR family member 4-like 2 DHRS4L2 0.0015
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0015
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0015
4496 C-terminal-binding protein 1 CTBP1 0.0015
2336 2,3-diketo-L-gulonate reductase dlgD 0.0015
413 Amidophosphoribosyltransferase PPAT 0.0014
2515 Amidophosphoribosyltransferase purF 0.0014
3714 Amidophosphoribosyltransferase purF 0.0014
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0014
484 Tyrosine-protein kinase ABL2 ABL2 0.0014
3923 Cholinesterase BCHE 0.0014
2683 Mono-ADP-ribosyltransferase C3 C3 0.0014
2599 Tyrosine-protein kinase HCK HCK 0.0014
5798 Mitogen-activated protein kinase 11 MAPK11 0.0014
4476 Mannitol dehydrogenase mtlD 0.0014
63 Malate dehydrogenase mdh 0.0014
2329 Malate dehydrogenase mdh 0.0014
3445 Malate dehydrogenase mdh 0.0014
4420 Malate dehydrogenase mdh 0.0014
4438 Malate dehydrogenase mdh 0.0014
2320 Thymidine kinase, cytosolic TK1 0.0014
277 Purine nucleoside phosphorylase PNP 0.0014
2870 Purine nucleoside phosphorylase punA 0.0014
2945 Purine nucleoside phosphorylase punA 0.0014
4659 Purine nucleoside phosphorylase TM_1596 0.0014
4825 Purine nucleoside phosphorylase TTHA1435 0.0014
531 Aldehyde dehydrogenase X, mitochondrial ALDH1B1 0.0013
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0013
6020 Aldehyde oxidase AOX1 0.0013
6824 Tyrosine-protein kinase Lyn LYN 0.0013
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0013
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0013
6344 ATP synthase subunit gamma, mitochondrial ATP5C1 0.0013
6343 ATP synthase subunit beta, mitochondrial ATP5B 0.0013
6342 ATP synthase subunit alpha, mitochondrial ATP5A1 0.0013
1152 Glycogen phosphorylase, muscle form PYGM 0.0013
4504 WbpP Not Available 0.0013
3296 Nicotinamide mononucleotide adenylyltransferase 1 NMNAT1 0.0013
3367 GDP-mannose 6-dehydrogenase algD 0.0013
4318 Siroheme synthase cysG 0.0013
4440 NADH peroxidase npr 0.0013
1864 RET proto-oncogene RET 0.0013
3736 Glyceraldehyde-3-phosphate dehydrogenase A gapA 0.0013
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0013
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0013
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0013
2799 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal Not Available 0.0013
4343 Alpha-glucosidase aglA 0.0013
2617 Nitric oxide synthase oxygenase nos 0.0013
2701 Nitric oxide synthase oxygenase nos 0.0013
789 Alpha-1D adrenergic receptor ADRA1D 0.0013
760 Fibroblast growth factor 1 FGF1 0.0013
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0013
365 Dihydrofolate reductase DHFR 0.0013
2381 Dihydrofolate reductase DFR1 0.0013
2833 Dihydrofolate reductase Not Available 0.0013
2931 Dihydrofolate reductase folA 0.0013
3544 Dihydrofolate reductase folA 0.0013
3682 Dihydrofolate reductase folA 0.0013
6642 Dihydrofolate reductase folA 0.0013
6756 Dihydrofolate reductase dfrA 0.0013
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0013
7 Nitric oxide synthase, inducible NOS2 0.0012
5294 Nucleoside diphosphate kinase A NME1 0.0012
247 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUFA1 0.0012
662 Fatty aldehyde dehydrogenase ALDH3A2 0.0012
104 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NDUFS6 0.0012
190 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 NDUFA4 0.0012
417 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NDUFB6 0.0012
216 Aldehyde dehydrogenase 3B2 ALDH3B2 0.0012
607 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NDUFA2 0.0012
300 NADH-ubiquinone oxidoreductase chain 4L MT-ND4L 0.0012
374 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NDUFB1 0.0012
99 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NDUFS5 0.0012
30 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NDUFV3 0.0012
446 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NDUFA7 0.0012
496 Aldehyde dehydrogenase 3B1 ALDH3B1 0.0012
324 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NDUFB4 0.0012
258 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial ALDH6A1 0.0012
343 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NDUFC1 0.0012
568 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NDUFB7 0.0012
598 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NDUFA11 0.0012
271 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial ALDH4A1 0.0012
829 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NDUFA12 0.0012
755 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NDUFA3 0.0012
353 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 NDUFA4L2 0.0012
272 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NDUFB10 0.0012
313 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NDUFB3 0.0012
555 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 0.0012
746 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NDUFB8 0.0012
475 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NDUFB2 0.0012
644 Heme oxygenase 2 HMOX2 0.0012
4982 Heme oxygenase 2 pbsA2 0.0012
525 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NDUFA5 0.0012
219 NADH-ubiquinone oxidoreductase chain 3 MT-ND3 0.0012
41 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NDUFS8 0.0012
236 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NDUFA6 0.0012
270 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NDUFB5 0.0012
112 L-lactate dehydrogenase A-like 6B LDHAL6B 0.0012
152 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NDUFV2 0.0012
848 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial IDH3G 0.0012
582 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NDUFA13 0.0012
196 D-beta-hydroxybutyrate dehydrogenase, mitochondrial BDH1 0.0012
327 Glutathione reductase gor 0.0012
5110 Glutathione reductase GR2 0.0012
602 Acyl carrier protein, mitochondrial NDUFAB1 0.0012
107 C-4 methylsterol oxidase SC4MOL 0.0012
608 NADH-ubiquinone oxidoreductase chain 4 MT-ND4 0.0012
405 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NDUFA8 0.0012
384 NADH-ubiquinone oxidoreductase chain 6 MT-ND6 0.0012
372 Estradiol 17-beta-dehydrogenase 3 HSD17B3 0.0012
145 Corticosteroid 11-beta-dehydrogenase isozyme 2 HSD11B2 0.0012
656 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 0.0012
729 GDP-L-fucose synthetase TSTA3 0.0012
3463 GDP-L-fucose synthetase fcl 0.0012
487 Aldo-keto reductase family 1 member C4 AKR1C4 0.0012
149 Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 0.0012
167 L-lactate dehydrogenase C chain LDHC 0.0012
326 L-lactate dehydrogenase A-like 6A LDHAL6A 0.0012
141 3-hydroxyisobutyrate dehydrogenase, mitochondrial HIBADH 0.0012
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.0012
3726 D-3-phosphoglycerate dehydrogenase serA 0.0012
4291 D-3-phosphoglycerate dehydrogenase serA 0.0012
206 3-keto-steroid reductase HSD17B7 0.0012
721 NADH-ubiquinone oxidoreductase chain 2 MT-ND2 0.0012
231 Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic GPD1 0.0012
91 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NDUFA10 0.0012
14 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial IDH3A 0.0012
50 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating NSDHL 0.0012
335 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NDUFA9 0.0012
616 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial IDH3B 0.0012
9 Estradiol 17-beta-dehydrogenase 2 HSD17B2 0.0012
671 Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial PDHA2 0.0012
628 Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial PDHA1 0.0012
539 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NDUFV1 0.0012
548 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NDUFS1 0.0012
609 15-hydroxyprostaglandin dehydrogenase [NAD+] HPGD 0.0012
34 7-dehydrocholesterol reductase DHCR7 0.0012
711 UDP-glucose 6-dehydrogenase UGDH 0.0012
3672 UDP-glucose 6-dehydrogenase hasB 0.0012
637 NADH-ubiquinone oxidoreductase chain 5 MT-ND5 0.0012
643 Peroxisomal bifunctional enzyme EHHADH 0.0012
288 Trifunctional enzyme subunit alpha, mitochondrial HADHA 0.0012
393 GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase H6PD 0.0012
3639 Thymidine phosphorylase deoA 0.0012
3936 Thymidine phosphorylase TYMP 0.0012
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.0012
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.0012
3333 Nicotinamide mononucleotide adenylyltransferase 3 NMNAT3 0.0012
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0012
2434 NH(3)-dependent NAD(+) synthetase nadE 0.0012
2910 NH(3)-dependent NAD(+) synthetase nadE 0.0012
3217 NH(3)-dependent NAD(+) synthetase nadE 0.0012
2826 Glucose--fructose oxidoreductase gfo 0.0012
3070 Adenosylhomocysteinase AHCY 0.0012
4424 Adenosylhomocysteinase PFE1050w 0.0012
6278 Adenosylhomocysteinase ahcY 0.0012
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.0012
3191 Histidinol dehydrogenase hisD 0.0012
6259 (3R)-hydroxymyristoyl-acyl carrier protein dehydratase fabZ 0.0012
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0012
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.0012
666 NADP-dependent malic enzyme ME1 0.0012
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0011
632 Alpha-1B adrenergic receptor ADRA1B 0.0011
857 Malate dehydrogenase, mitochondrial MDH2 0.0011
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0011
2404 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PIK3CG 0.0011
640 Aldehyde dehydrogenase 1A3 ALDH1A3 0.0011
11 NAD(P) transhydrogenase, mitochondrial NNT 0.0011
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0011
489 Monocarboxylate transporter 2 SLC16A7 0.0011
2240 Cell division protein kinase 2 CDK2 0.0011
74 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial DLAT 0.0011
2286 Isocitrate dehydrogenase [NADP] icd 0.0011
2302 Isocitrate dehydrogenase [NADP] icd 0.0011
2771 Isocitrate dehydrogenase [NADP] icd 0.0011
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0011
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0011
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0011
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0011
3587 Gastrotropin FABP6 0.0011
4491 DNA ligase, NAD-dependent ligA 0.0011
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0011
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0011
296 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial MTHFD2 0.0011
6026 Alcohol dehydrogenase 6 ADH6 0.001
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.001
627 11-cis retinol dehydrogenase RDH5 0.001
626 Cysteine dioxygenase type 1 CDO1 0.001
110 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.001
248 Pyrroline-5-carboxylate reductase 1 PYCR1 0.001
802 Pyrroline-5-carboxylate reductase 2 PYCR2 0.001
2762 UDP-glucose 4-epimerase GALE 0.001
3461 UDP-glucose 4-epimerase galE 0.001
5818 Folate receptor alpha FOLR1 0.001
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.001
13 Aminomethyltransferase, mitochondrial AMT 0.001
556 Alpha-1A adrenergic receptor ADRA1A 0.001
6149 Solute carrier family 22 member 10 SLC22A10 0.001
1192 Sulfotransferase 1A1 SULT1A1 0.001
84 Nuclear receptor 0B1 NR0B1 0.001
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.001
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.001
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.001
467 Delta-type opioid receptor OPRD1 0.001
696 Kappa-type opioid receptor OPRK1 0.001
6168 Solute carrier family 22 member 16 SLC22A16 0.001
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.001
57 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I HSD3B1 0.0009
847 Mu-type opioid receptor OPRM1 0.0009
6014 Cytochrome P450 2A13 CYP2A13 0.0009
654 Flavin reductase BLVRB 0.0009
279 Tyrosinase TYR 0.0009
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0009
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0009
810 Heme oxygenase 1 HMOX1 0.0009
3391 Heme oxygenase 1 pbsA1 0.0009
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0009
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0009
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0009
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0009
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0009
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0008
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0008
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0008
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0008
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0008
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0008
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0008
6085 Fatty acid-binding protein, intestinal FABP2 0.0008
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.0007
822 Aldose reductase AKR1B1 0.0007
76 Nitric-oxide synthase, brain NOS1 0.0007
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0007
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0007
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0006
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0006
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0006
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0006
146 Androgen receptor AR 0.0006
291 Nitric-oxide synthase, endothelial NOS3 0.0006
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0006
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0006
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0006
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0006
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0006
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0005
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0005
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0005
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0005
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0005
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