DT-Web

DB03721 - O-Sialic Acid


Identification
Name O-Sialic Acid
Accession Number DB03721 (EXPT02909)
Type small molecule
Description An N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518)
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 309.2699
Groups experimental
Monoisotopic Weight 309.105981211
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Fiber protein
Name Fiber protein
Gene Name L5
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.8696
Sialoadhesin
Name Sialoadhesin
Gene Name SIGLEC1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Zinc-alpha-2-glycoprotein
Name Zinc-alpha-2-glycoprotein
Gene Name AZGP1
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.7551
Coat protein VP1
Name Coat protein VP1
Gene Name Not Available
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.7663
Fiber protein
Name Fiber protein
Gene Name L5
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.8696
Liver carboxylesterase 1
Name Liver carboxylesterase 1
Gene Name CES1
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.885
Tetanus toxin
Name Tetanus toxin
Gene Name tetX
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.6335
Cholera enterotoxin subunit B
Name Cholera enterotoxin subunit B
Gene Name ctxB
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.9539
Botulinum neurotoxin type B
Name Botulinum neurotoxin type B
Gene Name botB
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.0365
P-selectin
Name P-selectin
Gene Name SELP
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.9603
Mannose-binding protein C
Name Mannose-binding protein C
Gene Name MBL2
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
E-selectin
Name E-selectin
Gene Name SELE
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.8506
Lithostathine 1 alpha
Name Lithostathine 1 alpha
Gene Name REG1A
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.789
Endo-N-acetylneuraminidase
Name Endo-N-acetylneuraminidase
Gene Name Not Available
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.071
Enterotoxin type B
Name Enterotoxin type B
Gene Name entB
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.8278
Neuraminidase
Name Neuraminidase
Gene Name NA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.012
Hemagglutinin-neuraminidase
Name Hemagglutinin-neuraminidase
Gene Name HN
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.4001

Enzymes


Liver carboxylesterase 1
Name Liver carboxylesterase 1
Gene Name CES1
Actions Not Available
References Not Available
DTHybrid score 0.885

Predictions


Id Partner name Gene Name Score
2942 Sialidase nanH 0.4679
3546 Sialidase nedA 0.4679
3140 Hemagglutinin-neuraminidase HN 0.4001
309 Antithrombin-III SERPINC1 0.274
4335 Trans-sialidase Not Available 0.2364
5481 Trans-sialidase TCTS-154 0.2364
1719 Heparanase HPSE 0.2099
1953 Proto-oncogene protein c-fos FOS 0.1872
4819 Hydrolase Not Available 0.1407
5249 Hydrolase Not Available 0.1407
5436 Hydrolase Not Available 0.1407
3176 Trypsin-1 PRSS1 0.1404
6692 Cholera toxin beta subunit ctxB 0.1204
1334 Tissue factor pathway inhibitor TFPI 0.0978
5482 Sialidase-2 NEU2 0.0977
3382 Glycolipid transfer protein GLTP 0.0973
4666 Fucose-binding lectin PA-IIL lecB 0.0901
2592 Beta-galactosidase lacZ 0.0861
2998 Sialic acid-binding Ig-like lectin 7 SIGLEC7 0.0807
4787 Envelope glycoprotein gp160 env 0.0761
4820 Envelope glycoprotein gp160 env 0.0761
5727 Envelope glycoprotein gp160 env 0.0761
2693 Heat-labile enterotoxin B chain eltB 0.0761
183 Vascular endothelial growth factor A VEGFA 0.0743
3626 Probable polysaccharide deacetylase pdaA pdaA 0.0624
239 Coagulation factor X F10 0.0611
2514 Phosphocarrier protein HPr ptsH 0.0545
5689 Phosphocarrier protein HPr ptsH 0.0545
3602 Anti-sigma F factor antagonist spoIIAA 0.0545
5686 Potassium voltage-gated channel subfamily C member 4 KCNC4 0.0544
2207 Rhodopsin RHO 0.052
4785 Ig gamma-1 chain C region IGHG1 0.052
10 Glycogen phosphorylase, liver form PYGL 0.0512
1184 Interferon beta IFNB1 0.0491
4542 Glutaminase 1 glsA1 0.0474
4544 Glutaminase 1 glsA1 0.0474
1373 Glucosylceramidase GBA 0.0473
3119 Fimbrial protein pilE1 0.0437
4318 Siroheme synthase cysG 0.0437
2530 Protein kinase C theta type PRKCQ 0.0436
2372 Bifunctional tail protein 9 0.0426
3453 Alkaline phosphatase phoA 0.0412
1152 Glycogen phosphorylase, muscle form PYGM 0.0411
2503 Phosphomannomutase/phosphoglucomutase algC 0.0394
5150 Endo-1,4-beta-xylanase Y xynY 0.0394
244 Angiotensin-converting enzyme ACE 0.0372
197 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial SDHA 0.0365
3689 Endoglucanase A celA 0.0364
5411 Slt-IIvB stxB2e 0.0362
5563 Galectin-2 LGALS2 0.0362
3009 Beta-glucanase Not Available 0.0362
5046 Ecotin eco 0.0362
2430 Chondroitinase B cslB 0.0362
5565 Inorganic polyphosphate/ATP-glucomannokinase ppgmk 0.0362
5554 D-galactose-binding periplasmic protein mglB 0.0362
5568 Endoglucanase C307 celC307 0.0362
3741 D-galactose-binding periplasmic protein precursor mglB 0.0362
1875 Pulmonary surfactant-associated protein D SFTPD 0.0362
3793 Aspartate ammonia-lyase aspA 0.0362
5553 Endoglucanase E1 Acel_0614 0.0362
5569 Endo-1,4-beta glucanase EngF engF 0.0362
5562 Hexokinase Not Available 0.0362
4668 Laminarinase TM_0024 0.0362
5559 Neopullulanase nplT 0.0362
4670 Cellulase B celB 0.0362
5570 Endoglucanase E-4 celD 0.0362
3744 Endoglucanase SS precursor celS 0.0362
4671 Endoglucanase C cenC 0.0362
4667 BH0236 protein BH0236 0.0362
6606 Platelet-activating factor acetylhydrolase IB subunit gamma PAFAH1B3 0.0348
4175 Platelet-activating factor acetylhydrolase PLA2G7 0.0348
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0332
1503 Galectin-7 LGALS7 0.0315
4509 Acetoin(diacetyl) reductase budC 0.0315
5247 Endo-1,4-beta-xylanase Not Available 0.0315
5248 Endo-1,4-beta-xylanase xlnA 0.0315
5250 Endo-1,4-beta-xylanase xyl 0.0315
5498 Maltoporin lamB 0.0315
5561 Maltoporin lamB 0.0315
3525 ADP-ribose pyrophosphatase, mitochondrial NUDT9 0.0315
5176 YtnJ moxC 0.0315
2728 Glucan 1,4-alpha-maltotetraohydrolase amyP 0.0315
4622 Amylase Not Available 0.0315
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0315
4669 Endo-1,4-beta-xylanase A xynA 0.0315
4715 Endo-1,4-beta-xylanase A xlnA 0.0315
5560 Endo-1,4-beta-xylanase A xynA 0.0315
5056 Maltooligosyltrehalose trehalohydrolase, putative treZ 0.0315
2705 Dimethyl sulfoxide reductase dmsA 0.0315
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0308
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0291
2856 Glucosamine-6-phosphate isomerase GNPDA1 0.0291
3747 Cellulase B precursor celB 0.0291
3153 Quinoprotein glucose dehydrogenase-B gdhB 0.0291
2564 Glucan 1,4-alpha-maltohexaosidase Not Available 0.0291
2541 Neopullulanase 1 tvaI 0.0291
2531 Alpha-amylase amyE 0.029
2948 Alpha-amylase amy 0.029
3169 Alpha-amylase Not Available 0.029
4811 Amylosucrase ams 0.029
2606 Neopullulanase 2 tvaII 0.029
3091 Maltodextrin phosphorylase malP 0.029
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0279
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0279
3225 Shiga toxin B-chain stxB 0.0275
4830 Aldose 1-epimerase galM 0.0274
2826 Glucose--fructose oxidoreductase gfo 0.0274
3365 Beta-amylase spoII 0.0274
1881 Hexokinase-1 HK1 0.0274
3480 Mannan endo-1,4-beta-mannosidase manA 0.0266
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0263
6614 Lactase-like protein LCTL 0.0262
3030 Salivary alpha-amylase AMY1A 0.0262
1675 Glucokinase GCK 0.0262
4662 Glucokinase glk 0.0262
2293 Cyclomaltodextrin glucanotransferase Not Available 0.0262
2508 Cyclomaltodextrin glucanotransferase cgt 0.0262
2523 Cyclomaltodextrin glucanotransferase cgt 0.0262
3207 Cyclomaltodextrin glucanotransferase amyA 0.0262
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0255
3668 Maltose-binding periplasmic protein precursor malE 0.0253
2448 Exoglucanase/xylanase [Includes: Exoglucanase cex 0.0253
2802 Endoglucanase G celCCG 0.0253
4692 A/G-specific adenine glycosylase mutY 0.0251
4272 POSSIBLE CELLULASE CELA1 celA1 0.0251
474 Acetylcholinesterase ACHE 0.0242
2440 Endoglucanase F celCCF 0.0237
20 Prostaglandin G/H synthase 1 PTGS1 0.0235
1588 Multidrug resistance protein 1 ABCB1 0.0233
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0228
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0228
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0228
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0228
2245 Xylose isomerase xylA 0.0222
2253 Xylose isomerase xylA 0.0222
2260 Xylose isomerase xylA 0.0222
2431 Xylose isomerase xylA 0.0222
2252 Endoglucanase 5A cel5A 0.022
4878 Glycoprotein hormones alpha chain CGA 0.0203
1052 Cytotoxic T-lymphocyte protein 4 CTLA4 0.0203
4850 Beta-2-glycoprotein 1 APOH 0.0203
1072 Granzyme B GZMB 0.0203
4877 Beta-mannanase man 0.0203
4871 Endo-beta-N-acetylglucosaminidase F3 endOF3 0.0203
1563 Platelet glycoprotein Ib alpha chain GP1BA 0.0203
757 Fusion glycoprotein F0 F 0.0203
4875 Fusion glycoprotein F0 F 0.0203
4880 Membrane cofactor protein CD46 0.0203
4889 Ig epsilon chain C region IGHE 0.0203
4856 CD209 antigen CD209 0.0203
4869 Major capsid protein A430L 0.0203
4852 Reticulon-4 receptor RTN4R 0.0203
4845 ADAM 33 ADAM33 0.0203
1354 Beta-glucuronidase GUSB 0.0203
442 Envelope glycoprotein gp41 0.0203
4859 Envelope glycoprotein env 0.0203
4189 Alpha-galactosidase A GLA 0.0203
4721 Beta-1,4-mannanase manA 0.0203
4882 Dipeptidyl aminopeptidase-like protein 6 DPP6 0.0203
3352 Structural polyprotein Not Available 0.0203
3628 Structural polyprotein Not Available 0.0203
4892 Structural polyprotein Not Available 0.0203
2427 Ferrichrome-iron receptor fhuA 0.0203
4513 Pancreatic alpha-amylase AMY2A 0.0202
4784 Beta-mannosidase manB 0.0179
6695 Beta-mannosidase BT_0458 0.0179
6858 Inactive carboxylesterase 4 CES1P1 0.0177
4193 Atrial natriuretic peptide clearance receptor NPR3 0.0177
119 Carcinoembryonic antigen-related cell adhesion molecule 1 CEACAM1 0.0177
793 T-cell surface antigen CD2 CD2 0.0177
4861 Interleukin-6 receptor alpha chain IL6R 0.0177
3837 Cytokine receptor common beta chain CSF2RB 0.0177
1379 Interleukin-12 subunit beta IL12B 0.0176
4890 Hemagglutinin HA 0.0175
6566 Hemagglutinin Not Available 0.0175
4411 DNA protection during starvation protein dps 0.0172
5423 UPF0010 protein HI1317 HI_1317 0.0172
5424 Endonuclease VIII-like 1 NEIL1 0.0172
3780 Lipoprotein nlpI precursor nlpI 0.0172
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0164
6120 Cation-independent mannose-6-phosphate receptor IGF2R 0.0162
3444 Cyanovirin-N Not Available 0.0161
1859 Prostatic acid phosphatase ACPP 0.0161
3258 Mannosyl-oligosaccharide alpha-1,2-mannosidase MSDC 0.0161
2297 Genome polyprotein Not Available 0.0156
2322 Genome polyprotein Not Available 0.0156
2694 Genome polyprotein Not Available 0.0156
2719 Genome polyprotein Not Available 0.0156
2860 Genome polyprotein Not Available 0.0156
2928 Genome polyprotein Not Available 0.0156
3160 Genome polyprotein Not Available 0.0156
3260 Genome polyprotein Not Available 0.0156
4783 Genome polyprotein Not Available 0.0156
5726 Genome polyprotein Not Available 0.0156
5779 Genome polyprotein Not Available 0.0156
5867 Genome polyprotein Not Available 0.0156
6253 Genome polyprotein Not Available 0.0156
6301 Genome polyprotein Not Available 0.0156
6380 Genome polyprotein Not Available 0.0156
6381 Genome polyprotein Not Available 0.0156
6437 Genome polyprotein Not Available 0.0156
6520 Genome polyprotein Not Available 0.0156
6521 Genome polyprotein Not Available 0.0156
6652 Genome polyprotein Not Available 0.0156
6734 Genome polyprotein Not Available 0.0156
6735 Genome polyprotein Not Available 0.0156
6736 Genome polyprotein Not Available 0.0156
6737 Genome polyprotein Not Available 0.0156
6738 Genome polyprotein Not Available 0.0156
6739 Genome polyprotein Not Available 0.0156
6744 Genome polyprotein Not Available 0.0156
6748 Genome polyprotein Not Available 0.0156
6894 Genome polyprotein Not Available 0.0156
6898 Genome polyprotein Not Available 0.0156
3923 Cholinesterase BCHE 0.0156
554 Low-density lipoprotein receptor LDLR 0.0155
4512 Cytochrome P450 3A4 CYP3A4 0.0155
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0152
18 High affinity immunoglobulin epsilon receptor subunit alpha FCER1A 0.0151
852 Heparin cofactor 2 SERPIND1 0.0151
3164 Biotin synthase bioB 0.015
3186 Soluble calcium-activated nucleotidase 1 CANT1 0.015
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0148
2577 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase MAN1B1 0.0145
3437 Eosinophil lysophospholipase CLC 0.0144
6500 Phospholipase A2 PLA2G1B 0.0141
3583 6-phosphogluconolactonase pgl 0.0138
595 Fibrinogen alpha chain FGA 0.0136
2178 Metabotropic glutamate receptor 5 GRM5 0.0136
1439 Lactotransferrin LTF 0.0136
1243 Cathepsin D CTSD 0.0133
1782 Neutrophil gelatinase-associated lipocalin LCN2 0.0131
3259 Autolysin lytA 0.013
3221 Cytochrome c4 cc4 0.013
958 Insulin-like growth factor 1 receptor IGF1R 0.013
6307 Ig gamma-2 chain C region IGHG2 0.0126
2581 Chondroitinase AC cslA 0.0126
6847 Lactase-phlorizin hydrolase LCT 0.0123
1141 Sialidase-1 NEU1 0.012
64 Neuraminidase NA 0.012
641 Neuraminidase NA 0.012
2676 Neuraminidase NA 0.012
3519 Neuraminidase NA 0.012
6007 Neuraminidase NA 0.012
113 S-adenosylmethionine decarboxylase proenzyme AMD1 0.0118
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0117
6131 Carbonic anhydrase 14 CA14 0.0114
3814 Complement C1r subcomponent C1R 0.0113
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0112
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0108
587 Serum albumin ALB 0.0108
3611 Cytidine deaminase cdd 0.0106
3707 Cytidine deaminase cdd 0.0106
4211 Cytidine deaminase CDA 0.0106
6142 Solute carrier family 22 member 8 SLC22A8 0.0103
76 Nitric-oxide synthase, brain NOS1 0.0103
3639 Thymidine phosphorylase deoA 0.0101
3936 Thymidine phosphorylase TYMP 0.0101
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.01
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0099
4757 Cytochrome P450 2C9 CYP2C9 0.0096
232 Corticosteroid-binding globulin SERPINA6 0.0095
952 Dipeptidyl peptidase 4 DPP4 0.009
24 Thymidylate synthase TMP1 0.0086
359 Thymidylate synthase TYMS 0.0086
2626 Thymidylate synthase thyA 0.0086
2729 Thymidylate synthase thyA 0.0086
5352 Thymidylate synthase THYA 0.0086
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0086
2164 Multidrug resistance-associated protein 4 ABCC4 0.0086
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0081
871 Glucocorticoid receptor NR3C1 0.0081
4118 Cytochrome P450 3A5 CYP3A5 0.008
54 Prothrombin F2 0.0071
6013 Cytochrome P450 2E1 CYP2E1 0.0068
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0067
6030 Cytochrome P450 2B6 CYP2B6 0.0066
4119 Cytochrome P450 2D6 CYP2D6 0.0066
122 P2Y purinoceptor 12 P2RY12 0.0064
4924 Cytochrome P450 2C8 CYP2C8 0.0061
636 Mitochondrial carnitine/acylcarnitine carrier protein SLC25A20 0.0059
109 Mitochondrial carnitine/acylcarnitine carrier protein CACL SLC25A29 0.0059
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0057
412 Peroxisomal carnitine O-octanoyltransferase CROT 0.0057
551 Carnitine O-acetyltransferase CRAT 0.0056
6016 Cytochrome P450 2C19 CYP2C19 0.0052
6168 Solute carrier family 22 member 16 SLC22A16 0.0051
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.0051
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.0051
862 Multidrug resistance-associated protein 1 ABCC1 0.0049
102 DNA topoisomerase I, mitochondrial TOP1MT 0.0043
4200 Cytochrome P450 1A2 CYP1A2 0.004
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.004
1353 DNA topoisomerase 1 TOP1 0.004
3552 DNA topoisomerase 1 topA 0.004
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0039
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0037
1757 Myeloperoxidase MPO 0.0035
6141 Sodium/bile acid cotransporter SLC10A1 0.0035
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0034
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0034
3947 Xanthine dehydrogenase/oxidase XDH 0.0034
6107 Cytochrome P450 3A7 CYP3A7 0.0032
833 Organic cation/carnitine transporter 1 SLC22A4 0.0032
2391 Ferrochelatase hemH 0.0031
6502 Ferrochelatase DKFZp686P18130 0.0031
1591 Ferrochelatase, mitochondrial FECH 0.0031
6042 Prostaglandin reductase 2 PTGR2 0.0031
776 Bile salt export pump ABCB11 0.003
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0029
1192 Sulfotransferase 1A1 SULT1A1 0.0029
118 Organic cation/carnitine transporter 2 SLC22A5 0.0028
6143 Solute carrier family 22 member 7 SLC22A7 0.0027
6043 Putative G-protein coupled receptor 44 GPR44 0.0027
6495 Cytochrome c oxidase subunit 7C, mitochondrial COX7C 0.0027
6496 Cytochrome c oxidase subunit 8A, mitochondrial COX8A 0.0027
6493 Cytochrome c oxidase subunit 6C COX6C 0.0027
6499 Cytochrome c oxidase polypeptide 7A1, mitochondrial COX7A1 0.0027
6491 Cytochrome c oxidase subunit 5A, mitochondrial COX5A 0.0027
6497 Cytochrome c oxidase subunit 6A2, mitochondrial COX6A2 0.0027
6494 Cytochrome c oxidase subunit 7B, mitochondrial COX7B 0.0027
6498 Cytochrome c oxidase subunit 6B1 COX6B1 0.0027
6489 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial COX4I1 0.0027
5793 Cytochrome c oxidase subunit 2 MT-CO2 0.0027
6559 Cytochrome c oxidase subunit 2 ctaC 0.0027
6669 Cytochrome c oxidase subunit 2 ctaC 0.0027
6490 Cytochrome c oxidase subunit 3 MT-CO3 0.0027
371 Cytochrome c oxidase subunit 1 MT-CO1 0.0027
6558 Cytochrome c oxidase subunit 1 ctaD 0.0027
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0026
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0026
6147 Solute carrier family 22 member 3 SLC22A3 0.0026
3587 Gastrotropin FABP6 0.0025
2540 Choloylglycine hydrolase cbh 0.0025
1313 Lactoylglutathione lyase GLO1 0.0025
6501 Fatty acid-binding protein, liver FABP1 0.0024
2981 Phospholipase A2, membrane associated PLA2G2A 0.0023
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0023
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0022
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0022
869 Estrogen receptor beta ESR2 0.0021
3809 Estrogen-related receptor gamma ESRRG 0.002
6137 Multidrug resistance-associated protein 6 ABCC6 0.0019
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0018
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0017
1898 Cytochrome P450 1B1 CYP1B1 0.0017
136 Estrogen receptor ESR1 0.0017
3811 Cytochrome P450 19A1 CYP19A1 0.0017
517 Alcohol dehydrogenase 1C ADH1C 0.0017
1024 Solute carrier family 22 member 11 SLC22A11 0.0016
5718 Cytochrome P450 2A6 CYP2A6 0.0015
290 Prostaglandin G/H synthase 2 PTGS2 0.0014
6024 Cytochrome P450 1A1 CYP1A1 0.0014
1729 Solute carrier family 22 member 6 SLC22A6 0.0012
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