DT-Web: DB00936

Identification
Name	Salicyclic acid
Accession Number	DB00936 (APRD01605)
Type	small molecule
Description	A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Structure	MOL SDF PDB SMILES InChI
Categories ^(*)	Anti-Infective Agents Antifungal Agents Keratolytic Agents
Molecular Weight	138.1207
Groups	approved
Monoisotopic Weight	138.031694058
Pharmacology
Indication	Key additive in many skin-care products for the treatment of acne, psoriasis, callouses, corns, keratosis pilaris and warts.
Mechanism of action	Salicylic acid directly and irreversibly inhibits the activity of both types of cyclo-oxygenases (COX-1 and COX-2) to decrease the formation of precursors of prostaglandins and thromboxanes from arachidonic acid. Salicylate may competitively inhibit prostaglandin formation. Salicylate's antirheumatic (nonsteroidal anti-inflammatory) actions are a result of its analgesic and anti-inflammatory mechanisms. Salicylic acid is a key ingredient in many skin-care products for the treatment of acne, psoriasis, calluses, corns, keratosis pilaris, and warts. It works by causing the cells of the epidermis to slough off more readily, preventing pores from clogging up, and allowing room for new cell growth. Because of its effect on skin cells, salicylic acid is used in several shampoos used to treat dandruff. Salicylic acid is also used as an active ingredient in gels which remove verrucas (plantar warts). Salicylic acid inhibits the oxidation of uridine-5-diphosphoglucose (UDPG) competitively with nicotinamide adenosine dinucleotide (NAD) and noncompetitively with UDPG. It also competitively inhibits the transferring of glucuronyl group of uridine-5-phosphoglucuronic acid (UDPGA) to the phenolic acceptor. The wound-healing retardation action of salicylates is probably due mainly to its inhibitory action on mucopolysaccharide synthesis.
Absorption	Not Available
Protein binding	Not Available
Biotransformation	Not Available
Route of elimination	Not Available
Toxicity	Oral rat LD50: 891 mg/kg. Inhalation rat LC50: > 900 mg/m3/1hr. Irritation: skin rabbit: 500 mg/24H mild. Eye rabbit: 100 mg severe. Investigated a mutagen and reproductive effector.
Affected organisms	Humans and other mammals
Interactions
Drug Interactions	Not Available
Food Interactions	Not Available

Prostaglandin G/H synthase 1
Name	Prostaglandin G/H synthase 1
Gene Name	PTGS1
Pharmacological action	yes
Actions	inhibitor
References	Moon C, Ahn M, Jee Y, Heo S, Kim S, Kim H, Sim KB, Koh CS, Shin YG, Shin T: Sodium salicylate-induced amelioration of experimental autoimmune encephalomyelitis in Lewis rats is associated with the suppression of inducible nitric oxide synthase and cyclooxygenases. Neurosci Lett. 2004 Feb 12;356(2):123-6. - Pubmed Graham GG, Scott KF: Mechanisms of action of paracetamol and related analgesics. Inflammopharmacology. 2003;11(4):401-13. - Pubmed Sun R, Carlson NG, Hemmert AC, Kishore BK: P2Y2 receptor-mediated release of prostaglandin E2 by IMCD is altered in hydrated and dehydrated rats: relevance to AVP-independent regulation of IMCD function. Am J Physiol Renal Physiol. 2005 Sep;289(3):F585-92. Epub 2005 Apr 19. - Pubmed Celik G, Pasaoglu G, Bavbek S, Abadoglu O, Dursun B, Mungan D, Misirligil Z: Tolerability of selective cyclooxygenase inhibitor, celecoxib, in patients with analgesic intolerance. J Asthma. 2005 Mar;42(2):127-31. - Pubmed Liu X, Lee TL, Wong PT: Cyclooxygenase-1 inhibition shortens the duration of diazepam-induced loss of righting reflex in mice. Anesth Analg. 2006 Jan;102(1):135-40. - Pubmed Vane JR: Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol. 1971 Jun 23;231(25):232-5. - Pubmed Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. - Pubmed
DTHybrid score	0.7129
Prostaglandin G/H synthase 2
Name	Prostaglandin G/H synthase 2
Gene Name	PTGS2
Pharmacological action	yes
Actions	inhibitor
References	Graham GG, Scott KF: Mechanisms of action of paracetamol and related analgesics. Inflammopharmacology. 2003;11(4):401-13. - Pubmed Fiebich BL, Chrubasik S: Effects of an ethanolic salix extract on the release of selected inflammatory mediators in vitro. Phytomedicine. 2004 Feb;11(2-3):135-8. - Pubmed Chae HJ, Chae SW, Reed JC, Kim HR: Salicylate regulates COX-2 expression through ERK and subsequent NF-kappaB activation in osteoblasts. Immunopharmacol Immunotoxicol. 2004 Feb;26(1):75-91. - Pubmed Wu KK: Aspirin and other cyclooxygenase inhibitors: new therapeutic insights. Semin Vasc Med. 2003 May;3(2):107-12. - Pubmed Elvira C, Gallardo A, Lacroix N, Schacht E, San Roman J: Incorporation of salicylic acid derivatives to hydrophilic copolymer systems with biomedical applications. J Mater Sci Mater Med. 2001 Jun;12(6):535-42. - Pubmed Vane JR: Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol. 1971 Jun 23;231(25):232-5. - Pubmed
DTHybrid score	0.6509
Aldo-keto reductase family 1 member C1
Name	Aldo-keto reductase family 1 member C1
Gene Name	AKR1C1
Pharmacological action	unknown
Actions	inhibitor
References	Dhagat U, Carbone V, Chung RP, Matsunaga T, Endo S, Hara A, El-Kabbani O: A salicylic acid-based analogue discovered from virtual screening as a potent inhibitor of human 20alpha-hydroxysteroid dehydrogenase. Med Chem. 2007 Nov;3(6):546-50. - Pubmed
DTHybrid score	0.5492

Cytochrome P450 2C9
Name	Cytochrome P450 2C9
Gene Name	CYP2C9
Actions	substrate
References	Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. - Pubmed
DTHybrid score	0.4638

Solute carrier family 22 member 6
Name	Solute carrier family 22 member 6
Gene Name	SLC22A6
Actions	inhibitor
References	Cihlar T, Ho ES: Fluorescence-based assay for the interaction of small molecules with the human renal organic anion transporter 1. Anal Biochem. 2000 Jul 15;283(1):49-55. - Pubmed Takeda M, Khamdang S, Narikawa S, Kimura H, Hosoyamada M, Cha SH, Sekine T, Endou H: Characterization of methotrexate transport and its drug interactions with human organic anion transporters. J Pharmacol Exp Ther. 2002 Aug;302(2):666-71. - Pubmed Race JE, Grassl SM, Williams WJ, Holtzman EJ: Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3). Biochem Biophys Res Commun. 1999 Feb 16;255(2):508-14. - Pubmed Uwai Y, Saito H, Inui K: Interaction between methotrexate and nonsteroidal anti-inflammatory drugs in organic anion transporter. Eur J Pharmacol. 2000 Dec 1;409(1):31-6. - Pubmed Apiwattanakul N, Sekine T, Chairoungdua A, Kanai Y, Nakajima N, Sophasan S, Endou H: Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes. Mol Pharmacol. 1999 May;55(5):847-54. - Pubmed
DTHybrid score	0.6199
Solute carrier family 22 member 10
Name	Solute carrier family 22 member 10
Gene Name	SLC22A10
Actions	inhibitor
References	Youngblood GL, Sweet DH: Identification and functional assessment of the novel murine organic anion transporter Oat5 (Slc22a19) expressed in kidney. Am J Physiol Renal Physiol. 2004 Aug;287(2):F236-44. Epub 2004 Apr 6. - Pubmed
DTHybrid score	0.145
Solute carrier family 22 member 8
Name	Solute carrier family 22 member 8
Gene Name	SLC22A8
Actions	inhibitor
References	Cha SH, Sekine T, Fukushima JI, Kanai Y, Kobayashi Y, Goya T, Endou H: Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney. Mol Pharmacol. 2001 May;59(5):1277-86. - Pubmed Takeda M, Khamdang S, Narikawa S, Kimura H, Hosoyamada M, Cha SH, Sekine T, Endou H: Characterization of methotrexate transport and its drug interactions with human organic anion transporters. J Pharmacol Exp Ther. 2002 Aug;302(2):666-71. - Pubmed Ohtsuki S, Kikkawa T, Mori S, Hori S, Takanaga H, Otagiri M, Terasaki T: Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier. J Pharmacol Exp Ther. 2004 Jun;309(3):1273-81. Epub 2004 Feb 4. - Pubmed
DTHybrid score	0.4978
Solute carrier family 22 member 11
Name	Solute carrier family 22 member 11
Gene Name	SLC22A11
Actions	inhibitor
References	Cha SH, Sekine T, Kusuhara H, Yu E, Kim JY, Kim DK, Sugiyama Y, Kanai Y, Endou H: Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta. J Biol Chem. 2000 Feb 11;275(6):4507-12. - Pubmed
DTHybrid score	0.3885
Solute carrier organic anion transporter family member 2B1
Name	Solute carrier organic anion transporter family member 2B1
Gene Name	SLCO2B1
Actions	substrate
References	Satoh H, Yamashita F, Tsujimoto M, Murakami H, Koyabu N, Ohtani H, Sawada Y: Citrus juices inhibit the function of human organic anion-transporting polypeptide OATP-B. Drug Metab Dispos. 2005 Apr;33(4):518-23. Epub 2005 Jan 7. - Pubmed
DTHybrid score	0.3251
Multidrug resistance protein 1
Name	Multidrug resistance protein 1
Gene Name	ABCB1
Actions	substrate
References	Faassen F, Vogel G, Spanings H, Vromans H: Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs. Int J Pharm. 2003 Sep 16;263(1-2):113-22. - Pubmed
DTHybrid score	0.4036
Monocarboxylate transporter 1
Name	Monocarboxylate transporter 1
Gene Name	SLC16A1
Actions	substrate
References	Tamai I, Sai Y, Ono A, Kido Y, Yabuuchi H, Takanaga H, Satoh E, Ogihara T, Amano O, Izeki S, Tsuji A: Immunohistochemical and functional characterization of pH-dependent intestinal absorption of weak organic acids by the monocarboxylic acid transporter MCT1. J Pharm Pharmacol. 1999 Oct;51(10):1113-21. - Pubmed
DTHybrid score	0.3347
Solute carrier family 22 member 7
Name	Solute carrier family 22 member 7
Gene Name	SLC22A7
Actions	substrate
References	Kobayashi Y, Ohshiro N, Shibusawa A, Sasaki T, Tokuyama S, Sekine T, Endou H, Yamamoto T: Isolation, characterization and differential gene expression of multispecific organic anion transporter 2 in mice. Mol Pharmacol. 2002 Jul;62(1):7-14. - Pubmed Sekine T, Cha SH, Tsuda M, Apiwattanakul N, Nakajima N, Kanai Y, Endou H: Identification of multispecific organic anion transporter 2 expressed predominantly in the liver. FEBS Lett. 1998 Jun 12;429(2):179-82. - Pubmed Morita N, Kusuhara H, Sekine T, Endou H, Sugiyama Y: Functional characterization of rat organic anion transporter 2 in LLC-PK1 cells. J Pharmacol Exp Ther. 2001 Sep;298(3):1179-84. - Pubmed
DTHybrid score	0.3374

Solute carrier family 22 member 6
Name	Solute carrier family 22 member 6
Gene Name	SLC22A6
Actions
References	Not Available
DTHybrid score	0.6199
Solute carrier family 22 member 10
Name	Solute carrier family 22 member 10
Gene Name	SLC22A10
Actions
References	Not Available
DTHybrid score	0.145
Solute carrier family 22 member 8
Name	Solute carrier family 22 member 8
Gene Name	SLC22A8
Actions
References	Not Available
DTHybrid score	0.4978
Solute carrier family 22 member 11
Name	Solute carrier family 22 member 11
Gene Name	SLC22A11
Actions
References	Not Available
DTHybrid score	0.3885
Solute carrier organic anion transporter family member 2B1
Name	Solute carrier organic anion transporter family member 2B1
Gene Name	SLCO2B1
Actions
References	Not Available
DTHybrid score	0.3251
Multidrug resistance protein 1
Name	Multidrug resistance protein 1
Gene Name	ABCB1
Actions
References	Not Available
DTHybrid score	0.4036
Monocarboxylate transporter 1
Name	Monocarboxylate transporter 1
Gene Name	SLC16A1
Actions
References	Not Available
DTHybrid score	0.3347
Solute carrier family 22 member 7
Name	Solute carrier family 22 member 7
Gene Name	SLC22A7
Actions
References	Not Available
DTHybrid score	0.3374

Id	Partner name	Gene Name	Score
4512	Cytochrome P450 3A4	CYP3A4	0.3239
4924	Cytochrome P450 2C8	CYP2C8	0.2384
6016	Cytochrome P450 2C19	CYP2C19	0.2235
4200	Cytochrome P450 1A2	CYP1A2	0.1806
6139	Solute carrier organic anion transporter family member 1A2	SLCO1A2	0.1627
4119	Cytochrome P450 2D6	CYP2D6	0.1518
489	Monocarboxylate transporter 2	SLC16A7	0.1422
2164	Multidrug resistance-associated protein 4	ABCC4	0.139
686	Aldo-keto reductase family 1 member C2	AKR1C2	0.1313
4118	Cytochrome P450 3A5	CYP3A5	0.1282
1732	ATP-binding cassette sub-family G member 2	ABCG2	0.127
1490	Solute carrier organic anion transporter family member 1B1	SLCO1B1	0.1262
1735	Canalicular multispecific organic anion transporter 1	ABCC2	0.1168
862	Multidrug resistance-associated protein 1	ABCC1	0.1168
118	Organic cation/carnitine transporter 2	SLC22A5	0.1011
500	Monocarboxylate transporter 4	SLC16A3	0.0967
1539	Oligopeptide transporter, small intestine isoform	SLC15A1	0.0938
6145	Solute carrier family 22 member 1	SLC22A1	0.0894
6157	Solute carrier organic anion transporter family member 1B3	SLCO1B3	0.0894
6030	Cytochrome P450 2B6	CYP2B6	0.0856
6160	Solute carrier organic anion transporter family member 3A1	SLCO3A1	0.0838
6018	UDP-glucuronosyltransferase 1-9	UGT1A9	0.083
6107	Cytochrome P450 3A7	CYP3A7	0.0814
6158	Solute carrier organic anion transporter family member 1C1	SLCO1C1	0.081
6013	Cytochrome P450 2E1	CYP2E1	0.0805
578	Endothelin-1 receptor	EDNRA	0.0802
1974	Oligopeptide transporter, kidney isoform	SLC15A2	0.08
373	Transthyretin	TTR	0.0776
6178	UDP-glucuronosyltransferase 2B7	UGT2B7	0.0724
6141	Sodium/bile acid cotransporter	SLC10A1	0.0718
6144	Solute carrier family 22 member 2	SLC22A2	0.0714
6024	Cytochrome P450 1A1	CYP1A1	0.0694
6155	ATP-binding cassette transporter sub-family C member 11	ABCC11	0.0692
1709	Canalicular multispecific organic anion transporter 2	ABCC3	0.0672
275	Arachidonate 5-lipoxygenase	ALOX5	0.0668
6022	UDP-glucuronosyltransferase 1-1	UGT1A1	0.0658
5718	Cytochrome P450 2A6	CYP2A6	0.0614
6136	Multidrug resistance-associated protein 5	ABCC5	0.061
6152	Solute carrier organic anion transporter family member 2A1	SLCO2A1	0.0601
1181	Alpha-1-acid glycoprotein 1	ORM1	0.0587
776	Bile salt export pump	ABCB11	0.0586
6153	Solute carrier organic anion transporter family member 4A1	SLCO4A1	0.0561
6176	UDP-glucuronosyltransferase 1-3	UGT1A3	0.0488
22	30S ribosomal protein S4	rpsD	0.0462
6714	30S ribosomal protein S4	rpsD	0.0462
672	Prostaglandin F2-alpha receptor	PTGFR	0.0454
238	Peroxisome proliferator-activated receptor gamma	PPARG	0.0453
140	30S ribosomal protein S9	rpsI	0.0435
6719	30S ribosomal protein S9	rpsI	0.0435
6725	30S ribosomal protein S9	rpsI	0.0435
338	DNA polymerase	UL30	0.0434
379	DNA polymerase	UL54	0.0434
697	DNA polymerase	ORF28	0.0434
2482	DNA polymerase	43	0.0434
4104	DNA polymerase	BALF5	0.0434
6106	Cytochrome P450 2C18	CYP2C18	0.0432
6167	Organic solute transporter subunit beta	OSTB	0.041
6166	Organic solute transporter subunit alpha	OSTA	0.0409
1757	Myeloperoxidase	MPO	0.0384
833	Organic cation/carnitine transporter 1	SLC22A4	0.0376
2184	Cystic fibrosis transmembrane conductance regulator	CFTR	0.0352
136	Estrogen receptor	ESR1	0.0351
230	ATP-binding cassette transporter sub-family C member 8	ABCC8	0.0339
645	Penicillin-binding protein 1A	mrcA	0.0338
5805	Penicillin-binding protein 1A	ponA	0.0338
6185	Penicillin-binding protein 1A	mrcA	0.0338
6799	Penicillin-binding protein 1A	pbpA	0.0338
6137	Multidrug resistance-associated protein 6	ABCC6	0.0337
631	3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMGCR	0.0335
3387	3-hydroxy-3-methylglutaryl-coenzyme A reductase	mvaA	0.0335
6218	Pannexin-1	PANX1	0.033
891	Dihydropteroate synthase	folP	0.0329
5359	Dihydropteroate synthase	folP	0.0329
7175	Dihydropteroate synthase	sulI	0.0329
633	Penicillin-binding proteins 1A/1B	pbpA	0.0324
543	Penicillin-binding protein 1B	mrcB	0.0319
6186	Penicillin-binding protein 1B	ponB	0.0319
6822	Penicillin-binding protein 1b	pbp1b	0.0319
6844	Penicillin-binding protein 1b	pbp1b	0.0319
558	Solute carrier family 12 member 1	SLC12A1	0.0304
1898	Cytochrome P450 1B1	CYP1B1	0.0302
6148	Multidrug resistance-associated protein 7	ABCC10	0.0287
492	Histamine H1 receptor	HRH1	0.0283
6150	Solute carrier organic anion transporter family member 4C1	SLCO4C1	0.0276
3811	Cytochrome P450 19A1	CYP19A1	0.0275
3947	Xanthine dehydrogenase/oxidase	XDH	0.0272
3923	Cholinesterase	BCHE	0.027
5353	Glutamate decarboxylase alpha	gadA	0.027
556	Alpha-1A adrenergic receptor	ADRA1A	0.0252
723	Cytosolic phospholipase A2	PLA2G4A	0.0252
6017	Cholesterol side-chain cleavage enzyme, mitochondrial	CYP11A1	0.0252
6012	Tryptophan 2,3-dioxygenase	TDO2	0.0251
527	Prostacyclin receptor	PTGIR	0.0249
438	Taste receptor type 1 member 2	TAS1R2	0.0248
2929	(S)-2-haloacid dehalogenase	dhlB	0.0248
2995	(S)-2-haloacid dehalogenase	Not Available	0.0248
6147	Solute carrier family 22 member 3	SLC22A3	0.0247
6177	UDP-glucuronosyltransferase 1-10	UGT1A10	0.0245
5650	NimA-related protein	DR_0842	0.024
6033	High affinity interleukin-8 receptor A	CXCR1	0.0239
1558	Transient receptor potential cation channel subfamily V member 1	TRPV1	0.0238
6085	Fatty acid-binding protein, intestinal	FABP2	0.0238
6599	HTH-type transcriptional regulator ttgR	ttgR	0.0235
146	Androgen receptor	AR	0.0234
6020	Aldehyde oxidase	AOX1	0.0233
6181	UDP-glucuronosyltransferase 1-8	UGT1A8	0.0232
1867	Major prion protein	PRNP	0.0232
6270	Group IIE secretory phospholipase A2	PLA2G2E	0.023
4132	Chloride channel protein ClC-Ka	CLCNKA	0.0229
709	ATP-sensitive inward rectifier potassium channel 1	KCNJ1	0.0229
1	Peptidoglycan synthetase ftsI	ftsI	0.0226
4155	Peptidoglycan synthetase ftsI	ftsI	0.0226
130	Prostacyclin synthase	PTGIS	0.0226
6040	6-phosphogluconate dehydrogenase, decarboxylating	PGD	0.0225
4604	Liver carboxylesterase 1	CES1	0.0224
1507	Cytochrome c	CYCS	0.0223
3686	Acyl-CoA thioesterase I precursor	tesA	0.0222
6154	Multidrug and toxin extrusion protein 1	SLC47A1	0.0221
6180	UDP-glucuronosyltransferase 2B4	UGT2B4	0.0218
3312	Fatty acid-binding protein, brain	FABP7	0.0217
115	Penicillin-binding protein 2	mrdA	0.021
6069	Penicillin-binding protein 2	mrdA	0.021
6118	Penicillin-binding protein 2	penA	0.021
6187	Penicillin-binding protein 2	pbpA	0.021
6686	Penicillin-binding protein 2	pbp2	0.021
6939	Penicillin-binding protein 2	mrdA	0.021
7163	Penicillin-binding protein 2	pbpA	0.021
3810	Catechol O-methyltransferase	COMT	0.0207
320	5-hydroxytryptamine 1A receptor	HTR1A	0.0206
3688	Branched-chain-amino-acid aminotransferase	ilvE	0.0205
357	Carbonic anhydrase 2	CA2	0.0205
183	Vascular endothelial growth factor A	VEGFA	0.0203
933	Proto-oncogene tyrosine-protein kinase Src	SRC	0.0202
887	DNA gyrase subunit B	gyrB	0.0201
4150	DNA gyrase subunit B	gyrB	0.0201
6225	DNA gyrase subunit B	gyrB	0.0201
6207	30S ribosomal protein S14	rpsN	0.02
6209	30S ribosomal protein S19	rpsS	0.02
6712	30S ribosomal protein S19	rpsS	0.02
6726	30S ribosomal protein S19	rpsS	0.02
872	Gamma-aminobutyric-acid receptor subunit alpha-1	GABRA1	0.0198
6140	Ileal sodium/bile acid cotransporter	SLC10A2	0.0198
502	5-hydroxytryptamine 2A receptor	HTR2A	0.0198
2016	Dipeptidase 1	DPEP1	0.0197
831	D(2) dopamine receptor	DRD2	0.0197
889	3-oxoacyl-[acyl-carrier-protein] synthase 1	fabB	0.0196
6860	3-oxoacyl-[acyl-carrier-protein] synthase 1	kasA	0.0196
592	Carbonic anhydrase 4	CA4	0.0194
824	Sodium-dependent serotonin transporter	SLC6A4	0.0193
3254	Bifunctional protein putA [Includes: Proline dehydrogenase	putA	0.0191
70	Type-1 angiotensin II receptor	AGTR1	0.019
295	Carbonic anhydrase 1	CA1	0.0189
73	Prostaglandin E2 receptor, EP1 subtype	PTGER1	0.0189
756	Sex hormone-binding globulin	SHBG	0.0188
1159	Interleukin-6	IL6	0.0185
2038	Inhibitor of nuclear factor kappa-B kinase subunit beta	IKBKB	0.0185
860	Nicotinamide N-methyltransferase	NNMT	0.0183
928	Nicotinic acid receptor 2	GPR109B	0.0183
583	Nicotinate-nucleotide pyrophosphorylase [carboxylating]	QPRT	0.0183
2442	Nicotinate-nucleotide pyrophosphorylase [carboxylating]	nadC	0.0183
2459	Nicotinate-nucleotide pyrophosphorylase [carboxylating]	nadC	0.0183
699	Nicotinic acid receptor 1	GPR109A	0.0183
6151	Monocarboxylate transporter 10	SLC16A10	0.0183
6043	Putative G-protein coupled receptor 44	GPR44	0.0183
244	Angiotensin-converting enzyme	ACE	0.0182
2222	Equilibrative nucleoside transporter 1	SLC29A1	0.018
220	Sodium channel protein type 5 subunit alpha	SCN5A	0.0178
4162	Potassium voltage-gated channel subfamily KQT member 3	KCNQ3	0.0178
124	Histamine H2 receptor	HRH2	0.0177
1086	Potassium voltage-gated channel subfamily KQT member 2	KCNQ2	0.0177
404	DNA gyrase subunit A	gyrA	0.0174
6224	DNA gyrase subunit A	gyrA	0.0174
5849	cAMP-dependent protein kinase type I-alpha regulatory subunit	PRKAR1A	0.0173
4098	Gamma-aminobutyric-acid receptor subunit beta-1	GABRB1	0.0169
1389	Transforming growth factor beta-1	TGFB1	0.0169
650	Aldo-keto reductase family 1 member C3	AKR1C3	0.0167
2249	Aspartate aminotransferase	aspC	0.0167
2671	Aspartate aminotransferase	aspC	0.0167
5490	Aspartate aminotransferase	Not Available	0.0167
24	Thymidylate synthase	TMP1	0.0166
359	Thymidylate synthase	TYMS	0.0166
2626	Thymidylate synthase	thyA	0.0166
2729	Thymidylate synthase	thyA	0.0166
5352	Thymidylate synthase	THYA	0.0166
6500	Phospholipase A2	PLA2G1B	0.0163
777	Tumor necrosis factor	TNF	0.0162
540	Sodium-dependent noradrenaline transporter	SLC6A2	0.0162
406	Prostaglandin E2 receptor, EP2 subtype	PTGER2	0.0161
806	Sodium/potassium-transporting ATPase alpha-1 chain	ATP1A1	0.0161
332	Beta-lactamase	blaZ	0.0159
2478	Beta-lactamase	ampC	0.0159
2613	Beta-lactamase	ampC	0.0159
2635	Beta-lactamase	ampC	0.0159
2700	Beta-lactamase	penP	0.0159
5445	Beta-lactamase	blaB	0.0159
6019	Beta-lactamase	SHV-7	0.0159
6701	Beta-lactamase	cphA	0.0159
3184	3-methyl-2-oxobutanoate hydroxymethyltransferase	panB	0.0159
3315	3-methyl-2-oxobutanoate hydroxymethyltransferase	panB	0.0159
3179	2-isopropylmalate synthase	leuA	0.0159
1119	Peroxiredoxin-5, mitochondrial	PRDX5	0.0159
33	Cystine/glutamate transporter	SLC7A11	0.0159
6031	Cytochrome P450 3A43	CYP3A43	0.0157
1284	Nuclear receptor subfamily 1 group I member 2	NR1I2	0.0156
3639	Thymidine phosphorylase	deoA	0.0154
3936	Thymidine phosphorylase	TYMP	0.0154
663	Solute carrier family 12 member 4	SLC12A4	0.0153
53	Solute carrier family 12 member 5	SLC12A5	0.0153
6101	Dimethylaniline monooxygenase [N-oxide-forming] 3	FMO3	0.0152
817	DNA topoisomerase 2-alpha	TOP2A	0.0152
1792	Tissue-type plasminogen activator	PLAT	0.015
2261	Major NAD(P)H-flavin oxidoreductase	Not Available	0.0149
871	Glucocorticoid receptor	NR3C1	0.0149
318	Alpha-2A adrenergic receptor	ADRA2A	0.0147
2320	Thymidine kinase, cytosolic	TK1	0.0146
1787	Nuclear factor NF-kappa-B p105 subunit	NFKB1	0.0144
310	Solute carrier family 12 member 2	SLC12A2	0.0143
101	Potassium voltage-gated channel subfamily H member 2	KCNH2	0.0143
6184	D-alanyl-D-alanine carboxypeptidase dacC	dacC	0.0143
6541	Peptostreptococcal albumin-binding protein	pab	0.0142
1650	Heme carrier protein 1	SLC46A1	0.0141
65	Matrix metalloproteinase-9	Not Available	0.014
6220	Aryl hydrocarbon receptor	AHR	0.014
867	Penicillin-binding protein 3	pbpC	0.014
6119	Penicillin-binding protein 3	pbp3	0.014
7154	Penicillin-binding protein 3	pbp3	0.014
7157	Penicillin-binding protein 3	LMHCC_2184	0.014
7162	Penicillin-binding protein 3	pbpB	0.014
7172	Penicillin-binding protein 3	pbp3	0.014
6102	Arylamine N-acetyltransferase 2	NAT2	0.0139
3917	Methylenetetrahydrofolate reductase	MTHFR	0.0139
122	P2Y purinoceptor 12	P2RY12	0.0137
1654	Interleukin-1 beta	IL1B	0.0137
468	Cytochrome P450 4A11	CYP4A11	0.0137
2021	Thrombomodulin	THBD	0.0135
778	Cysteinyl leukotriene receptor 1	CYSLTR1	0.0135
2981	Phospholipase A2, membrane associated	PLA2G2A	0.0134
23	D(1A) dopamine receptor	DRD1	0.0134
273	Apoptosis regulator Bcl-2	BCL2	0.0134
365	Dihydrofolate reductase	DHFR	0.0134
2381	Dihydrofolate reductase	DFR1	0.0134
2833	Dihydrofolate reductase	Not Available	0.0134
2931	Dihydrofolate reductase	folA	0.0134
3544	Dihydrofolate reductase	folA	0.0134
3682	Dihydrofolate reductase	folA	0.0134
6642	Dihydrofolate reductase	folA	0.0134
6756	Dihydrofolate reductase	dfrA	0.0134
805	Cytochrome P450 11B1, mitochondrial	CYP11B1	0.0133
1502	Peroxisome proliferator-activated receptor delta	PPARD	0.0132
5626	Nucleoside diphosphate kinase B	NME2	0.0132
703	NADPH azoreductase	azr	0.0132
185	Vasopressin V1a receptor	AVPR1A	0.0132
3014	Ribonuclease UK114	HRSP12	0.0132
5428	Replication protein	repA	0.0132
3617	Non-heme chloroperoxidase	cpo	0.0132
5426	Non-heme chloroperoxidase	cpo	0.0132
5427	Hydroxyquinol 1,2-dioxygenase	chqB	0.0132
3718	Hydrogen peroxide-inducible genes activator	oxyR	0.0132
3018	HTH-type transcriptional regulator malT	malT	0.0132
3426	Glutamine synthetase	glnA	0.0131
3987	Glutamine synthetase	GLUL	0.0131
3760	Penicillin-binding protein 5 precursor	dacA	0.0131
632	Alpha-1B adrenergic receptor	ADRA1B	0.013
322	Vasopressin V2 receptor	AVPR2	0.0129
6126	Carbonic anhydrase 7	CA7	0.0129
3685	Catabolite gene activator	crp	0.0127
4655	Adenylate cyclase	cyaC	0.0127
4759	Adenylate cyclase	cyaB2	0.0127
3334	Deacetoxycephalosporin C synthetase	cefE	0.0127
4217	Telomerase reverse transcriptase	TERT	0.0125
1971	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	PDE4A	0.0125
819	Penicillin-binding protein 4	dacB	0.0125
850	Vasopressin V1b receptor	AVPR1B	0.0122
308	30S ribosomal protein S12	rpsL	0.0122
6704	30S ribosomal protein S12	rpsL	0.0122
103	Muscarinic acetylcholine receptor M1	CHRM1	0.0122
580	Gamma-aminobutyric-acid receptor subunit alpha-3	GABRA3	0.0122
847	Mu-type opioid receptor	OPRM1	0.0122
423	Gamma-aminobutyric-acid receptor subunit alpha-2	GABRA2	0.0122
787	Vitamin K epoxide reductase complex subunit 1	VKORC1	0.0121
6104	Dimethylaniline monooxygenase [N-oxide-forming] 1	FMO1	0.012
3941	Amine oxidase [flavin-containing] A	MAOA	0.012
1198	Serum paraoxonase/arylesterase 1	PON1	0.012
6223	Penicillin-binding protein 1C	pbpC	0.012
4094	Gamma-aminobutyric acid type B receptor, subunit 2	GABBR2	0.0119
459	Retinoic acid receptor RXR-alpha	RXRA	0.0118
193	Beta-1 adrenergic receptor	ADRB1	0.0117
2958	Probable tautomerase ydcE	pptA	0.0113
2573	Cocaine esterase	cocE	0.0113
7263	Cocaine esterase	Not Available	0.0113
853	Farnesyl pyrophosphate synthetase	FDPS	0.0113
696	Kappa-type opioid receptor	OPRK1	0.0112
3115	Ras-related protein Rab-9	RAB9A	0.0111
280	4-aminobutyrate aminotransferase, mitochondrial	ABAT	0.0111
3603	Chlorocatechol 1,2-dioxygenase	clcA	0.0111
494	Caspase-1	CASP1	0.0111
731	HIV-1 protease	HIV-1 protease	0.011
614	Progesterone receptor	PGR	0.011
4790	Glycosyltransferase GtfA	gtfA	0.011
869	Estrogen receptor beta	ESR2	0.0109
1405	Thiopurine S-methyltransferase	TPMT	0.0109
4760	Mll3241 protein	mll3241	0.0109
766	Beta-2 adrenergic receptor	ADRB2	0.0109
3587	Gastrotropin	FABP6	0.0108
293	Gamma-glutamyl hydrolase	GGH	0.0107
5294	Nucleoside diphosphate kinase A	NME1	0.0107
274	Muscarinic acetylcholine receptor M5	CHRM5	0.0107
5997	Tumor necrosis factor ligand superfamily member 11	TNFSF11	0.0107
811	Translocator protein	TSPO	0.0107
795	Branched-chain-amino-acid aminotransferase, mitochondrial	BCAT2	0.0107
6837	Serine/threonine-protein kinase 17B	STK17B	0.0106
6836	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial	HIBCH	0.0106
2853	14 kDa fatty acid-binding protein	Not Available	0.0105
467	Delta-type opioid receptor	OPRD1	0.0105
523	Gamma-aminobutyric-acid receptor subunit alpha-5	GABRA5	0.0105
822	Aldose reductase	AKR1B1	0.0105
2211	Fatty acid-binding protein, heart	FABP3	0.0105
844	Epidermal growth factor receptor	EGFR	0.0105
450	Muscarinic acetylcholine receptor M4	CHRM4	0.0104
781	ATP-sensitive inward rectifier potassium channel 11	KCNJ11	0.0104
51	Muscarinic acetylcholine receptor M3	CHRM3	0.0104
6025	UDP-glucuronosyltransferase 1-4	UGT1A4	0.0103
617	Muscarinic acetylcholine receptor M2	CHRM2	0.0103
1178	Adenosine A2a receptor	ADORA2A	0.0103
5818	Folate receptor alpha	FOLR1	0.0102
1192	Sulfotransferase 1A1	SULT1A1	0.0102
4122	Histone deacetylase 2	HDAC2	0.0101
465	Calmodulin	CALM1	0.0101
3804	Sodium channel protein type 4 subunit alpha	SCN4A	0.01
477	DNA topoisomerase 4 subunit A	parC	0.0099
886	DNA topoisomerase 4 subunit A	parC	0.0099
6226	DNA topoisomerase 4 subunit A	parC	0.0099
4221	Vascular endothelial growth factor	VEGF	0.0099
5816	Cadherin-5	CDH5	0.0099
260	Cytochrome P450 51	ERG11	0.0098
761	Cytochrome P450 51	ERG11	0.0098
3163	Cytochrome P450 51	cyp51	0.0098
1439	Lactotransferrin	LTF	0.0098
6042	Prostaglandin reductase 2	PTGR2	0.0097
1648	Elastin	ELN	0.0097
1039	Histone deacetylase 9	HDAC9	0.0096
182	2-oxoglutarate dehydrogenase E1 component, mitochondrial	OGDH	0.0096
1457	Long-chain-fatty-acid--CoA ligase 4	ACSL4	0.0095
566	Serotransferrin	TF	0.0094
1714	Mitogen-activated protein kinase 3	MAPK3	0.0094
16	Adenosine A1 receptor	ADORA1	0.0094
1656	CYP2B protein	CYP2B	0.0093
240	Gamma-aminobutyric acid type B receptor, subunit 1	GABBR1	0.0093
2077	Caspase-3	CASP3	0.0093
6656	UDP-glucuronosyltransferase 3A1	UGT3A1	0.0092
170	Succinate semialdehyde dehydrogenase, mitochondrial	ALDH5A1	0.0092
2461	D-alanyl-D-alanine carboxypeptidase	Not Available	0.0092
5756	D-alanyl-D-alanine carboxypeptidase	dac	0.0092
2599	Tyrosine-protein kinase HCK	HCK	0.0092
6014	Cytochrome P450 2A13	CYP2A13	0.0091
380	Cytochrome P450 17A1	CYP17A1	0.009
1244	Low-density lipoprotein receptor-related protein 2	LRP2	0.009
773	Folylpolyglutamate synthase, mitochondrial	FPGS	0.009
6002	Prostaglandin E2 receptor EP4 subtype	PTGER4	0.009
789	Alpha-1D adrenergic receptor	ADRA1D	0.0089
2183	Fatty acid-binding protein, adipocyte	FABP4	0.0089
4674	2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase	cumD	0.0087
3961	G protein-activated inward rectifier potassium channel 4	KCNJ5	0.0087
782	ADP/ATP translocase 2	SLC25A5	0.0086
688	ADP/ATP translocase 3	SLC25A6	0.0086
243	Ribosyldihydronicotinamide dehydrogenase [quinone]	NQO2	0.0086
952	Dipeptidyl peptidase 4	DPP4	0.0086
2693	Heat-labile enterotoxin B chain	eltB	0.0086
698	B-Raf proto-oncogene serine/threonine-protein kinase	BRAF	0.0086
4120	NADPH--cytochrome P450 reductase	POR	0.0085
482	Glycine receptor subunit alpha-1	GLRA1	0.0085
6645	D-amino-acid oxidase	DAO	0.0084
4100	Gamma-aminobutyric-acid receptor subunit beta-2	GABRB2	0.0084
630	Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial	ACADSB	0.0084
4773	Deoxycytidine kinase	DCK	0.0084
4099	Gamma-aminobutyric-acid receptor subunit beta-3	GABRB3	0.0084
594	Thyroxine-binding globulin	SERPINA7	0.0083
4131	Prostaglandin E2 receptor, EP3 subtype	PTGER3	0.0083
199	Monocarboxylate transporter 8	SLC16A2	0.0082
590	5-hydroxytryptamine 2C receptor	HTR2C	0.0082
4238	50S ribosomal protein L4	rplD	0.0081
5578	50S ribosomal protein L4	rplD	0.0081
6173	50S ribosomal protein L4	rplD	0.0081
6219	50S ribosomal protein L4	rplD	0.0081
6131	Carbonic anhydrase 14	CA14	0.0081
559	NADH-ubiquinone oxidoreductase chain 1	MT-ND1	0.008
6525	Group IID secretory phospholipase A2	PLA2G2D	0.008
818	50S ribosomal protein L10	rplJ	0.0079
61	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	0.0079
2644	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	0.0079
2710	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	0.0079
737	Mineralocorticoid receptor	NR3C2	0.0079
485	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	PDE3A	0.0078
858	Potassium voltage-gated channel subfamily A member 1	KCNA1	0.0078
521	ATP-binding cassette transporter sub-family C member 9	ABCC9	0.0077
758	Thyroid hormone receptor alpha	THRA	0.0077
6344	ATP synthase subunit gamma, mitochondrial	ATP5C1	0.0077
6342	ATP synthase subunit alpha, mitochondrial	ATP5A1	0.0077
6343	ATP synthase subunit beta, mitochondrial	ATP5B	0.0077
706	Glutamate [NMDA] receptor subunit 3A	GRIN3A	0.0077
241	Calcium-transporting ATPase type 2C member 1	ATP2C1	0.0077
1275	Estrogen sulfotransferase	SULT1E1	0.0076
654	Flavin reductase	BLVRB	0.0076
40	RAF proto-oncogene serine/threonine-protein kinase	RAF1	0.0076
705	Glutamate receptor 1	GRIA1	0.0076
6182	Cytochrome P450 2J2	CYP2J2	0.0075
436	5-hydroxytryptamine 2B receptor	HTR2B	0.0075
1313	Lactoylglutathione lyase	GLO1	0.0075
4237	50S ribosomal protein L22	rplV	0.0074
342	P protein [Includes: DNA-directed DNA polymerase	P	0.0073
612	P protein [Includes: DNA-directed DNA polymerase	P	0.0073
4115	Voltage-dependent L-type calcium channel subunit alpha-1D	CACNA1D	0.0073
3939	Amine oxidase [flavin-containing] B	MAOB	0.0073
537	ATP synthase delta chain, mitochondrial	ATP5D	0.0072
389	Amiloride-sensitive cation channel 2, neuronal	ACCN2	0.0071
3932	Glutathione S-transferase A2	GSTA2	0.0071
2287	Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase	ATIC	0.0071
478	Voltage-dependent L-type calcium channel subunit alpha-1C	CACNA1C	0.0071
3806	cGMP-dependent 3',5'-cyclic phosphodiesterase	PDE2A	0.0071
132	ATP-binding cassette sub-family A member 1	ABCA1	0.0071
567	Receptor tyrosine-protein kinase erbB-2	ERBB2	0.0071
2404	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	PIK3CG	0.007
504	Mast/stem cell growth factor receptor	KIT	0.0069
364	Corticosteroid 11-beta-dehydrogenase isozyme 1	HSD11B1	0.0069
346	Thyroid hormone receptor beta-1	THRB	0.0069
823	Fibroblast growth factor receptor 2	FGFR2	0.0068
541	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	PDE4B	0.0068
2159	Quinone oxidoreductase	CRYZ	0.0067
341	5-hydroxytryptamine 3 receptor	HTR3A	0.0067
6259	(3R)-hydroxymyristoyl-acyl carrier protein dehydratase	fabZ	0.0067
661	ADP/ATP translocase 1	SLC25A4	0.0067
713	Sodium-dependent dopamine transporter	SLC6A3	0.0067
4111	Voltage-dependent L-type calcium channel subunit alpha-1S	CACNA1S	0.0067
36	Insulin receptor	INSR	0.0066
2236	Casein kinase II subunit alpha	CSNK2A1	0.0066
885	5-hydroxytryptamine 1B receptor	HTR1B	0.0065
1050	Bile salt sulfotransferase	SULT2A1	0.0064
634	Squalene monooxygenase	SQLE	0.0064
7196	Squalene monooxygenase	ERG1	0.0064
3432	Multidrug-efflux transporter 1 regulator	bmrR	0.0063
4476	Mannitol dehydrogenase	mtlD	0.0063
6103	Arylamine N-acetyltransferase 1	NAT1	0.0063
133	Dihydropterate synthase	sulI	0.0063
2347	Proto-oncogene serine/threonine-protein kinase Pim-1	PIM1	0.0062
29	Tubulin beta-1 chain	TUBB1	0.0062
4116	Dihydropteroate synthetase	Not Available	0.0062
110	Pyruvate dehydrogenase E1 component subunit beta, mitochondrial	PDHB	0.0062
4110	Voltage-dependent L-type calcium channel subunit beta-2	CACNB2	0.0062
427	Substance-P receptor	TACR1	0.0061
695	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	PDE10A	0.0061
17	Proto-oncogene tyrosine-protein kinase ABL1	ABL1	0.0061
3823	Cytokine receptor common gamma chain	IL2RG	0.0061
1852	Microtubule-associated protein 2	MAP2	0.006
509	Thymidine kinase	TK	0.006
570	Thymidine kinase	TK	0.006
2559	Thymidine kinase	TK	0.006
3430	Thymidine kinase	tdk	0.006
3518	Thymidine kinase	TK	0.006
5301	Thymidine kinase	tdk	0.006
5771	Thymidine kinase	ORF36	0.006
7009	Thymidine kinase	ORF36	0.006
134	Tryptophan 5-hydroxylase 1	TPH1	0.006
725	5-hydroxytryptamine 1D receptor	HTR1D	0.006
6093	Gamma-aminobutyric acid receptor subunit delta	GABRD	0.006
6087	Gamma-aminobutyric acid receptor subunit gamma-1	GABRG1	0.006
6089	Gamma-aminobutyric acid receptor subunit epsilon	GABRE	0.006
78	Acetyl-CoA acetyltransferase, mitochondrial	ACAT1	0.0059
1353	DNA topoisomerase 1	TOP1	0.0059
3552	DNA topoisomerase 1	topA	0.0059
646	Malate dehydrogenase, cytoplasmic	MDH1	0.0059
397	Monocarboxylate transporter 3	SLC16A8	0.0059
635	Estradiol 17-beta-dehydrogenase 8	HSD17B8	0.0058
385	Potassium-transporting ATPase alpha chain 1	ATP4A	0.0058
666	NADP-dependent malic enzyme	ME1	0.0058
3382	Glycolipid transfer protein	GLTP	0.0058
195	Monocarboxylate transporter 7	SLC16A6	0.0058
218	Monocarboxylate transporter 5	SLC16A4	0.0058
429	Monocarboxylate transporter 6	SLC16A5	0.0058
6122	Carbonic anhydrase 3	CA3	0.0058
471	Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)	SLC6A14	0.0057
707	72 kDa type IV collagenase	MMP2	0.0057
5328	Prostaglandin F synthase	Tb11.02.2310	0.0057
2180	3-phosphoinositide-dependent protein kinase 1	PDPK1	0.0056
759	Free fatty acid receptor 1	FFAR1	0.0056
1818	Long-chain-fatty-acid--CoA ligase 3	ACSL3	0.0056
217	Estradiol 17-beta-dehydrogenase 1	HSD17B1	0.0056
11	NAD(P) transhydrogenase, mitochondrial	NNT	0.0056
530	Gamma-aminobutyric-acid receptor subunit alpha-4	GABRA4	0.0056
137	FolC bifunctional protein [Includes: Folylpolyglutamate synthase	folC	0.0055
3007	Carbonic anhydrase 12	CA12	0.0055
4205	Carbonic anhydrase 9	CA9	0.0055
904	Glutathione S-transferase P	GSTP1	0.0055
466	Solute carrier family 12 member 3	SLC12A3	0.0055
828	Phenylalanine-4-hydroxylase	PAH	0.0054
3109	Phenylalanine-4-hydroxylase	phhA	0.0054
964	Voltage-dependent T-type calcium channel subunit alpha-1H	CACNA1H	0.0054
6861	Alcohol dehydrogenase [NADP+]	AKR1A1	0.0054
5346	Oxidoreductase, aldo/keto reductase family	TM_1009	0.0054
4403	Protein iolS	iolS	0.0054
5330	General stress protein 69	yhdN	0.0054
5322	Oxidoreductase ydhF	ydhF	0.0054
5333	Alcohol dehydrogenase, iron-containing	TM_0920	0.0054
5326	Oxidoreductase, short chain dehydrogenase/reductase family	TM_0441	0.0054
5157	Dehydrogenase/reductase SDR family member 11	DHRS11	0.0054
5332	MtdA bifunctional protein	mtdA	0.0054
5342	NADH-dependent butanol dehydrogenase, putative	TM_0820	0.0054
3772	3-oxoacyl-[acyl-carrier-protein] reductase	fabG	0.0054
3778	NAD(P) transhydrogenase subunit beta	pntB	0.0054
676	Tyrosine 3-monooxygenase	TH	0.0054
5343	NADP-dependent fatty aldehyde dehydrogenase	aldH	0.0054
4252	Penicillin-binding protein 5	dacA	0.0053
7	Nitric oxide synthase, inducible	NOS2	0.0053
724	Interleukin-2 receptor alpha chain	IL2RA	0.0053
717	Interleukin-2 receptor subunit beta	IL2RB	0.0053
228	Beta platelet-derived growth factor receptor	PDGFRB	0.0053
3808	Dihydropteroate synthase 2	folP2	0.0052
3601	Dihydropteroate synthase 1	folP1	0.0052
3807	Dihydropteroate synthase 1	folP1	0.0052
444	Alcohol dehydrogenase 1B	ADH1B	0.0052
159	Penicillin-binding protein 2B	penA	0.0052
6121	Penicillin-binding protein 2B	penA	0.0052
52	Pyruvate kinase isozymes R/L	PKLR	0.0052
4226	Uridine phosphorylase 2	UPP2	0.0052
841	Gamma-aminobutyric-acid receptor subunit alpha-6	GABRA6	0.0051
474	Acetylcholinesterase	ACHE	0.0051
629	Alpha-2B adrenergic receptor	ADRA2B	0.0051
253	Sodium/potassium-transporting ATPase gamma chain	FXYD2	0.0051
2616	Ganglioside GM2 activator	GM2A	0.0051
4484	2,5-diketo-D-gluconic acid reductase A	dkgA	0.005
232	Corticosteroid-binding globulin	SERPINA6	0.005
6086	Gamma-aminobutyric acid receptor subunit gamma-2	GABRG2	0.005
4109	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	PDE4C	0.005
6027	Alkaline phosphatase, tissue-nonspecific isozyme	ALPL	0.005
1053	BC269730_2	FADS1	0.0049
610	Calcium-activated potassium channel subunit alpha 1	KCNMA1	0.0049
1395	Sodium/calcium exchanger 1	SLC8A1	0.0049
1141	Sialidase-1	NEU1	0.0049
64	Neuraminidase	NA	0.0049
641	Neuraminidase	NA	0.0049
2676	Neuraminidase	NA	0.0049
3026	Neuraminidase	NA	0.0049
3519	Neuraminidase	NA	0.0049
6007	Neuraminidase	NA	0.0049
771	Pyruvate carboxylase, mitochondrial	PC	0.0049
277	Purine nucleoside phosphorylase	PNP	0.0049
2870	Purine nucleoside phosphorylase	punA	0.0049
2945	Purine nucleoside phosphorylase	punA	0.0049
4659	Purine nucleoside phosphorylase	TM_1596	0.0049
4825	Purine nucleoside phosphorylase	TTHA1435	0.0049
5924	Microtubule-associated protein 4	MAP4	0.0048
5923	Microtubule-associated protein tau	MAPT	0.0048
1302	Dihydropyrimidine dehydrogenase [NADP+]	DPYD	0.0048
1629	Transcription factor AP-1	JUN	0.0048
291	Nitric-oxide synthase, endothelial	NOS3	0.0048
679	C-1-tetrahydrofolate synthase, cytoplasmic	MTHFD1	0.0048
407	Vascular endothelial growth factor receptor 2	KDR	0.0048
950	Alpha platelet-derived growth factor receptor	PDGFRA	0.0048
6206	DNA-directed RNA polymerase subunit beta'	rpoC	0.0048
4225	Uridine phosphorylase 1	UPP1	0.0047
6179	UDP-glucuronosyltransferase 2B17	UGT2B17	0.0047
813	Neuronal acetylcholine receptor subunit alpha-2	CHRNA2	0.0047
98	Pyruvate kinase isozymes M1/M2	PKM2	0.0047
2375	ADP-L-glycero-D-manno-heptose-6-epimerase	hldD	0.0047
204	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE5A	0.0047
716	5-hydroxytryptamine 7 receptor	HTR7	0.0047
5073	Ferredoxin--NADP reductase	petH	0.0047
5076	Ferredoxin--NADP reductase	fpr	0.0047
5119	Ferredoxin--NADP reductase	petH	0.0047
5121	Ferredoxin--NADP reductase	fpr	0.0047
5075	Sulfite reductase [NADPH] flavoprotein alpha-component	cysJ	0.0047
161	Tubulin beta chain	TUBB	0.0046
312	Tubulin beta chain	TUB2	0.0046
4103	Proteasome subunit beta type 2	PSMB2	0.0046
4102	Proteasome subunit beta type 5	PSMB5	0.0046
4101	Proteasome subunit beta type 1	PSMB1	0.0046
762	Voltage-dependent calcium channel subunit alpha-2/delta-1	CACNA2D1	0.0046
1799	Glucose-6-phosphate 1-dehydrogenase	G6PD	0.0046
2630	Glucose-6-phosphate 1-dehydrogenase	zwf	0.0046
2305	Isocitrate dehydrogenase [NADP] cytoplasmic	IDH1	0.0046
4582	Putative pteridine reductase 2	ptr2	0.0046
2286	Isocitrate dehydrogenase [NADP]	icd	0.0046
2302	Isocitrate dehydrogenase [NADP]	icd	0.0046
2771	Isocitrate dehydrogenase [NADP]	icd	0.0046
4628	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase	gapN	0.0046
780	Retinoic acid receptor RXR-gamma	RXRG	0.0046
989	L-xylulose reductase	DCXR	0.0046
908	Glutathione S-transferase theta-1	GSTT1	0.0046
3446	NADP-dependent alcohol dehydrogenase	adh	0.0046
2636	Shikimate dehydrogenase	aroE	0.0046
3515	Shikimate dehydrogenase	aroE	0.0046
638	D(3) dopamine receptor	DRD3	0.0045
106	Cannabinoid receptor 2	CNR2	0.0045
6501	Fatty acid-binding protein, liver	FABP1	0.0045
413	Amidophosphoribosyltransferase	PPAT	0.0045
2515	Amidophosphoribosyltransferase	purF	0.0045
3714	Amidophosphoribosyltransferase	purF	0.0045
1618	High affinity nerve growth factor receptor	NTRK1	0.0045
6339	Ig kappa chain V-II region RPMI 6410	Not Available	0.0044
284	DNA-directed RNA polymerase beta chain	rpoB	0.0044
5773	DNA-directed RNA polymerase beta chain	rpoB	0.0044
245	Large neutral amino acids transporter small subunit 1	SLC7A5	0.0044
114	Alanine--glyoxylate aminotransferase 2, mitochondrial	AGXT2	0.0044
147	Aldehyde dehydrogenase, mitochondrial	ALDH2	0.0044
49	Endothelin B receptor	EDNRB	0.0044
5645	DNA topoisomerase 4 subunit B	parE	0.0044
6227	DNA topoisomerase 4 subunit B	parE	0.0044
68	Cannabinoid receptor 1	CNR1	0.0043
6862	Aldo-keto reductase family 1 member B10	AKR1B10	0.0043
5698	Riboflavin synthase alpha chain	ribE	0.0043
571	Melatonin receptor type 1A	MTNR1A	0.0042
362	Melatonin receptor type 1B	MTNR1B	0.0042
4531	Putative ketoacyl reductase	actIII	0.0042
6297	Prostaglandin reductase 1	PTGR1	0.0042
88	Retinoic acid receptor RXR-beta	RXRB	0.0042
3062	Aspartate-semialdehyde dehydrogenase	asd	0.0042
5325	2,4-dienoyl-CoA reductase, mitochondrial	DECR1	0.0042
528	5-hydroxytryptamine 1E receptor	HTR1E	0.0042
2358	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	PDE4D	0.0042
408	Riboflavin kinase	RFK	0.0041
2207	Rhodopsin	RHO	0.0041
2675	Pteridine reductase 1	PTR1	0.0041
3573	2,4-dienoyl-CoA reductase [NADPH]	fadH	0.004
6508	Putative uncharacterized protein	srtB	0.004
6543	Putative uncharacterized protein	tcp14	0.004
6615	Putative uncharacterized protein	MT0785	0.004
6623	Putative uncharacterized protein	Not Available	0.004
6806	Putative uncharacterized protein	AGR_C_2535	0.004
6813	Putative uncharacterized protein	SAV4671	0.004
6815	Putative uncharacterized protein	AFE_1514	0.004
6819	Putative uncharacterized protein	RUMGNA_03254	0.004
6825	Putative uncharacterized protein	CV_3270	0.004
6088	Gamma-aminobutyric acid receptor subunit gamma-3	GABRG3	0.004
6090	Gamma-aminobutyric acid receptor subunit pi	GABRP	0.004
6092	Gamma-aminobutyric acid receptor subunit rho-2	GABRR2	0.004
6115	Gamma-aminobutyric acid receptor subunit rho-3	GABRR3	0.004
4161	Furin	FURIN	0.004
1124	Sepiapterin reductase	SPR	0.004
6169	ATP-binding cassette sub-family A member 5	ABCA5	0.004
6091	Gamma-aminobutyric acid receptor subunit theta	GABRQ	0.004
6146	High affinity copper uptake protein 1	SLC31A1	0.004
142	Gamma-aminobutyric-acid receptor subunit rho-1	GABRR1	0.0039
1995	Sodium channel protein type 9 subunit alpha	SCN9A	0.0039
15	Voltage-dependent T-type calcium channel subunit alpha-1I	CACNA1I	0.0039
4177	Proto-oncogene tyrosine-protein kinase receptor ret	RET	0.0039
3809	Estrogen-related receptor gamma	ESRRG	0.0039
4097	Neuronal acetylcholine receptor subunit alpha-9	CHRNA9	0.0039
6124	Carbonic anhydrase 5B, mitochondrial	CA5B	0.0039
5482	Sialidase-2	NEU2	0.0039
2408	Tyrosine-protein kinase SYK	SYK	0.0039
6067	Penicillin binding protein 2a	mecA	0.0038
6677	Myelin P2 protein	PMP2	0.0038
194	NADH dehydrogenase [ubiquinone] 1 subunit C2	NDUFC2	0.0038
6138	Multidrug resistance protein 3	ABCB4	0.0038
26	Vascular endothelial growth factor receptor 3	FLT4	0.0037
462	Intermediate conductance calcium-activated potassium channel protein 4	KCNN4	0.0037
1789	Lymphotoxin-alpha	LTA	0.0037
1269	Tumor necrosis factor receptor superfamily member 1B	TNFRSF1B	0.0037
768	FK506-binding protein 1A	FKBP1A	0.0037
102	DNA topoisomerase I, mitochondrial	TOP1MT	0.0037
76	Nitric-oxide synthase, brain	NOS1	0.0037
2472	Voltage-gated potassium channel	kcsA	0.0037
6366	Voltage-gated potassium channel	kcsA	0.0037
3802	Sodium channel protein type 2 subunit alpha	SCN2A	0.0037
511	5-hydroxytryptamine 1F receptor	HTR1F	0.0036
198	Sodium channel protein type 10 subunit alpha	SCN10A	0.0036
32	Vascular endothelial growth factor receptor 1	FLT1	0.0036
2157	NAD(P)H dehydrogenase [quinone] 1	NQO1	0.0036
595	Fibrinogen alpha chain	FGA	0.0036
997	Protein kinase C beta type	PRKCB	0.0035
259	Microsomal triglyceride transfer protein large subunit	MTTP	0.0035
268	Adenosine A2b receptor	ADORA2B	0.0035
378	Alpha-2C adrenergic receptor	ADRA2C	0.0035
2449	Tubulin alpha-3 chain	TUBA1A	0.0035
6171	Solute carrier family 28 member 3	SLC28A3	0.0035
54	Prothrombin	F2	0.0035
535	Voltage-dependent T-type calcium channel subunit alpha-1G	CACNA1G	0.0034
158	Sodium channel protein type 1 subunit alpha	SCN1A	0.0034
4192	DNA topoisomerase 2-beta	TOP2B	0.0034
4160	Voltage-dependent calcium channel subunit alpha-2/delta-2	CACNA2D2	0.0034
3970	Voltage-dependent N-type calcium channel subunit alpha-1B	CACNA1B	0.0034
517	Alcohol dehydrogenase 1C	ADH1C	0.0034
1517	Beta-3 adrenergic receptor	ADRB3	0.0034
6123	Carbonic anhydrase 5A, mitochondrial	CA5A	0.0033
514	Potassium voltage-gated channel subfamily H member 6	KCNH6	0.0033
772	Potassium voltage-gated channel subfamily H member 7	KCNH7	0.0033
918	Glutamate receptor, ionotropic kainate 2	GRIK2	0.0033
4113	Voltage-dependent L-type calcium channel subunit alpha-1F	CACNA1F	0.0033
2178	Metabotropic glutamate receptor 5	GRM5	0.0033
1970	Protein kinase C alpha type	PRKCA	0.0033
2391	Ferrochelatase	hemH	0.0033
6502	Ferrochelatase	DKFZp686P18130	0.0033
1591	Ferrochelatase, mitochondrial	FECH	0.0033
620	Bifunctional dihydrofolate reductase-thymidylate synthase	Not Available	0.0033
4784	Beta-mannosidase	manB	0.0032
6695	Beta-mannosidase	BT_0458	0.0032
3957	Adenosine deaminase	ADA	0.0032
1196	Complement decay-accelerating factor	CD55	0.0032
464	Glutamate [NMDA] receptor subunit epsilon-2	GRIN2B	0.0031
2499	Tubulin beta-2C chain	TUBB2C	0.0031
319	Opioid receptor, sigma 1	OPRS1	0.0031
1525	Heparin-binding growth factor 2	FGF2	0.0031
921	Glutamate receptor 2	GRIA2	0.0031
4203	Histamine N-methyltransferase	HNMT	0.0031
5787	Angiopoietin-1 receptor	TEK	0.0031
1227	Cytochrome b	MT-CYB	0.0031
6386	Cytochrome b	petB	0.0031
6937	Cytochrome b	MT-CYB	0.0031
674	Dihydroorotate dehydrogenase homolog, mitochondrial	PFF0160c	0.0031
66	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II	HSD3B2	0.0031
951	Macrophage colony-stimulating factor 1 receptor	CSF1R	0.003
1864	RET proto-oncogene	RET	0.003
1950	Epithelial discoidin domain-containing receptor 1	DDR1	0.003
6170	ATP-binding cassette sub-family A member 3	ABCA3	0.003
6094	BCR/ABL fusion protein isoform X9	BCR/ABL fusion	0.003
4210	Toll-like receptor 4	TLR4	0.003
837	Glutamate [NMDA] receptor subunit epsilon-1	GRIN2A	0.003
621	Periplasmic [Fe] hydrogenase 1	Not Available	0.003
3813	Fibrinogen gamma chain	FGG	0.0029
3812	Fibrinogen beta chain [Contains: Fibrinopeptide B]	FGB	0.0029
3830	Calreticulin	CALR	0.0029
947	Neuronal acetylcholine receptor subunit alpha-4	CHRNA4	0.0029
4095	Neuronal acetylcholine receptor subunit alpha-7	CHRNA7	0.0029
683	Potassium transporter	GK0582	0.0029
6497	Cytochrome c oxidase subunit 6A2, mitochondrial	COX6A2	0.0029
6496	Cytochrome c oxidase subunit 8A, mitochondrial	COX8A	0.0029
6495	Cytochrome c oxidase subunit 7C, mitochondrial	COX7C	0.0029
1374	Natriuretic peptides B	NPPB	0.0029
6493	Cytochrome c oxidase subunit 6C	COX6C	0.0029
6499	Cytochrome c oxidase polypeptide 7A1, mitochondrial	COX7A1	0.0029
6494	Cytochrome c oxidase subunit 7B, mitochondrial	COX7B	0.0029
6498	Cytochrome c oxidase subunit 6B1	COX6B1	0.0029
80	Peroxisome proliferator-activated receptor alpha	PPARA	0.0029
424	Dihydroorotate dehydrogenase, mitochondrial	DHODH	0.0029
6489	Cytochrome c oxidase subunit 4 isoform 1, mitochondrial	COX4I1	0.0029
6491	Cytochrome c oxidase subunit 5A, mitochondrial	COX5A	0.0029
6490	Cytochrome c oxidase subunit 3	MT-CO3	0.0029
1827	Gap junction alpha-1 protein	GJA1	0.0029
5793	Cytochrome c oxidase subunit 2	MT-CO2	0.0029
6559	Cytochrome c oxidase subunit 2	ctaC	0.0029
6669	Cytochrome c oxidase subunit 2	ctaC	0.0029
1908	Vascular cell adhesion protein 1	VCAM1	0.0029
371	Cytochrome c oxidase subunit 1	MT-CO1	0.0029
6558	Cytochrome c oxidase subunit 1	ctaD	0.0029
515	26S proteasome non-ATPase regulatory subunit 1	PSMD1	0.0029
522	26S proteasome non-ATPase regulatory subunit 2	PSMD2	0.0029
1435	Synaptic vesicle glycoprotein 2A	SV2A	0.0028
2998	Sialic acid-binding Ig-like lectin 7	SIGLEC7	0.0028
2808	Chloramphenicol acetyltransferase 3	cat3	0.0028
1278	Pro-epidermal growth factor	EGF	0.0028
1200	AMBP protein	AMBP	0.0028
3866	Serum amyloid A protein	SAA1	0.0028
1932	Apolipoprotein E	APOE	0.0028
5126	Arginase	rocF	0.0027
1010	Cytochrome P450 51A1	CYP51A1	0.0027
6232	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	GNAS	0.0027
6233	Adenylate cyclase type 2	ADCY2	0.0027
6234	Adenylate cyclase type 5	ADCY5	0.0027
796	Inosine-5'-monophosphate dehydrogenase 2	IMPDH2	0.0027
1025	Aquaporin-1	AQP1	0.0027
2300	Lysozyme	E	0.0027
3633	Lysozyme	R	0.0027
5597	Lysozyme	17	0.0027
5934	Cytochrome P450 26A1	CYP26A1	0.0027
702	UMP-CMP kinase	CMPK1	0.0027
1992	Vitamin D-binding protein	GC	0.0027
830	Glutamate dehydrogenase 2, mitochondrial	GLUD2	0.0027
6034	Hydroxyindole O-methyltransferase	ASMT	0.0027
6035	Nuclear receptor ROR-beta	RORB	0.0027
6036	Eosinophil peroxidase	EPX	0.0027
838	Inosine-5'-monophosphate dehydrogenase 1	IMPDH1	0.0026
162	Retinoic acid receptor gamma-1	RARG	0.0026
1291	cAMP response element-binding protein	CREB1	0.0026
2540	Choloylglycine hydrolase	cbh	0.0026
87	Hypoxanthine-guanine phosphoribosyltransferase	HPRT1	0.0026
6047	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	PDE1A	0.0026
857	Malate dehydrogenase, mitochondrial	MDH2	0.0026
432	D(4) dopamine receptor	DRD4	0.0026
992	Protein tyrosine kinase 2 beta	PTK2B	0.0026
2417	Chloramphenicol acetyltransferase	cat	0.0025
3278	Chloramphenicol acetyltransferase	cat	0.0025
6432	Transporter	snf	0.0025
750	Voltage-dependent calcium channel gamma-1 subunit	CACNG1	0.0025
1385	Angiotensin-converting enzyme 2	ACE2	0.0025
2810	Dr hemagglutinin structural subunit	draA	0.0025
2718	Chloramphenicol 3-O phosphotransferase	Not Available	0.0025
229	Retinoic acid receptor beta	RARB	0.0025
239	Coagulation factor X	F10	0.0025
6168	Solute carrier family 22 member 16	SLC22A16	0.0025
4787	Envelope glycoprotein gp160	env	0.0025
4820	Envelope glycoprotein gp160	env	0.0025
5727	Envelope glycoprotein gp160	env	0.0025
1541	Metalloproteinase	mmp20	0.0025
5692	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	PDE1B	0.0025
109	Mitochondrial carnitine/acylcarnitine carrier protein CACL	SLC25A29	0.0025
636	Mitochondrial carnitine/acylcarnitine carrier protein	SLC25A20	0.0025
83	Alpha-aminoadipic semialdehyde synthase, mitochondrial	AASS	0.0024
730	Retinoic acid receptor alpha	RARA	0.0024
1561	Troponin C, slow skeletal and cardiac muscles	TNNC1	0.0024
201	Glutamate dehydrogenase 1, mitochondrial	GLUD1	0.0024
3616	Fatty acid-binding protein, epidermal	FABP5	0.0024
5431	Lipid binding protein	Not Available	0.0024
5433	UPF0230 protein TM_1468	TM_1468	0.0024
5430	Hepatocyte nuclear factor 4-gamma	HNF4G	0.0024
3814	Complement C1r subcomponent	C1R	0.0024
6263	cAMP-dependent protein kinase catalytic subunit alpha	PRKACA	0.0024
4148	Serine/threonine-protein kinase mTOR	MTOR	0.0024
2297	Genome polyprotein	Not Available	0.0024
2322	Genome polyprotein	Not Available	0.0024
2694	Genome polyprotein	Not Available	0.0024
2719	Genome polyprotein	Not Available	0.0024
2860	Genome polyprotein	Not Available	0.0024
2928	Genome polyprotein	Not Available	0.0024
3160	Genome polyprotein	Not Available	0.0024
3260	Genome polyprotein	Not Available	0.0024
4783	Genome polyprotein	Not Available	0.0024
5726	Genome polyprotein	Not Available	0.0024
5779	Genome polyprotein	Not Available	0.0024
5867	Genome polyprotein	Not Available	0.0024
6253	Genome polyprotein	Not Available	0.0024
6301	Genome polyprotein	Not Available	0.0024
6380	Genome polyprotein	Not Available	0.0024
6381	Genome polyprotein	Not Available	0.0024
6437	Genome polyprotein	Not Available	0.0024
6520	Genome polyprotein	Not Available	0.0024
6521	Genome polyprotein	Not Available	0.0024
6652	Genome polyprotein	Not Available	0.0024
6734	Genome polyprotein	Not Available	0.0024
6735	Genome polyprotein	Not Available	0.0024
6736	Genome polyprotein	Not Available	0.0024
6737	Genome polyprotein	Not Available	0.0024
6738	Genome polyprotein	Not Available	0.0024
6739	Genome polyprotein	Not Available	0.0024
6744	Genome polyprotein	Not Available	0.0024
6748	Genome polyprotein	Not Available	0.0024
6894	Genome polyprotein	Not Available	0.0024
6898	Genome polyprotein	Not Available	0.0024
3611	Cytidine deaminase	cdd	0.0024
3707	Cytidine deaminase	cdd	0.0024
4211	Cytidine deaminase	CDA	0.0024
6231	Pepsin A	PGA3	0.0024
6459	Glycodelin	PAEP	0.0024
5432	Trafficking protein particle complex subunit 3	TRAPPC3	0.0024
765	Indoleamine 2,3-dioxygenase	IDO1	0.0023
505	Glutamate [NMDA] receptor subunit epsilon-3	GRIN2C	0.0023
439	Glutamate [NMDA] receptor subunit epsilon-4	GRIN2D	0.0023
94	5-hydroxytryptamine 4 receptor	HTR4	0.0023
5682	Ribonuclease pancreatic	RNASE1	0.0023
624	Guanidinoacetate N-methyltransferase	GAMT	0.0022
401	Glutamate [NMDA] receptor subunit zeta-1	GRIN1	0.0022
605	Fumarate reductase flavoprotein subunit	frdA	0.0022
2709	Fumarate reductase flavoprotein subunit	SO_0970	0.0022
3673	Fumarate reductase flavoprotein subunit	fccA	0.0022
4912	Fumarate reductase flavoprotein subunit	ifcA	0.0022
6549	Fumarate reductase flavoprotein subunit	frdA	0.0022
2782	Complement C1s subcomponent	C1S	0.0022
4992	Cytochrome c peroxidase	Not Available	0.0022
4209	ATP-sensitive inward rectifier potassium channel 8	KCNJ8	0.0022
3480	Mannan endo-1,4-beta-mannosidase	manA	0.0022
6023	Cytochrome P450 11B2, mitochondrial	CYP11B2	0.0022
6161	Probable low affinity copper uptake protein 2	SLC31A2	0.0021
751	Potassium channel subfamily K member 6	KCNK6	0.0021
3437	Eosinophil lysophospholipase	CLC	0.0021
718	Folate receptor gamma	FOLR3	0.0021
299	Folate receptor beta	FOLR2	0.0021
804	Mitochondrial folate transporter/carrier	SLC25A32	0.0021
3868	Calcineurin subunit B isoform 2	PPP3R2	0.0021
421	Calcium signal-modulating cyclophilin ligand	CAMLG	0.0021
200	Carnitine O-palmitoyltransferase 2, mitochondrial	CPT2	0.0021
451	Carnitine O-palmitoyltransferase I, liver isoform	CPT1A	0.0021
4112	Voltage-dependent L-type calcium channel subunit beta-4	CACNB4	0.0021
4114	Voltage-dependent L-type calcium channel subunit beta-3	CACNB3	0.0021
551	Carnitine O-acetyltransferase	CRAT	0.0021
412	Peroxisomal carnitine O-octanoyltransferase	CROT	0.0021
3817	Complement C1q subcomponent subunit C	C1QC	0.0021
3815	Complement C1q subcomponent subunit A	C1QA	0.0021
3816	Complement C1q subcomponent subunit B	C1QB	0.0021
6174	50S ribosomal protein L32	rpmF	0.0021
331	Retinol-binding protein I, cellular	RBP1	0.0021
3876	Aromatic-L-amino-acid decarboxylase	DDC	0.0021
1102	Low affinity immunoglobulin gamma Fc region receptor III-B	FCGR3B	0.0021
3818	Low affinity immunoglobulin gamma Fc region receptor III-A	FCGR3A	0.0021
3819	Low affinity immunoglobulin gamma Fc region receptor II-a	FCGR2A	0.0021
3821	Low affinity immunoglobulin gamma Fc region receptor II-c	FCGR2C	0.0021
1123	Eosinophil cationic protein	RNASE3	0.002
3820	Low affinity immunoglobulin gamma Fc region receptor II-b	FCGR2B	0.002
392	Voltage-dependent P/Q-type calcium channel subunit alpha-1A	CACNA1A	0.002
283	SEC14-like protein 2	SEC14L2	0.002
153	Dopamine beta-hydroxylase	DBH	0.002
6755	Poliovirus receptor	PVR	0.002
6163	Copper-transporting ATPase 2	ATP7B	0.002
6165	Copper-transporting ATPase 1	ATP7A	0.002
172	Potassium channel subfamily K member 1	KCNK1	0.002
2107	Microtubule-associated protein 1A	MAP1A	0.002
784	High affinity immunoglobulin gamma Fc receptor I	FCGR1A	0.0019
677	Choline-phosphate cytidylyltransferase A	PCYT1A	0.0019
487	Aldo-keto reductase family 1 member C4	AKR1C4	0.0019
6045	Voltage-dependent calcium channel subunit alpha-2/delta-3	CACNA2D3	0.0019
251	Alcohol dehydrogenase 1A	ADH1A	0.0019
591	Glutamate [NMDA] receptor subunit 3B	GRIN3B	0.0019
333	Voltage-dependent L-type calcium channel subunit beta-1	CACNB1	0.0019
518	Peroxidase/catalase T	katG	0.0019
165	FL cytokine receptor	FLT3	0.0019
1638	Solute carrier family 2, facilitated glucose transporter member 2	SLC2A2	0.0019
810	Heme oxygenase 1	HMOX1	0.0019
3391	Heme oxygenase 1	pbsA1	0.0019
4152	Superoxide dismutase [Cu-Zn]	SOD1	0.0019
569	Retinal dehydrogenase 2	ALDH1A2	0.0018
3854	Basic fibroblast growth factor receptor 1	FGFR1	0.0018
611	Retinal dehydrogenase 1	ALDH1A1	0.0018
816	Biliverdin reductase A	BLVRA	0.0018
792	Aldehyde dehydrogenase, dimeric NADP-preferring	ALDH3A1	0.0018
579	Alcohol dehydrogenase class 4 mu/sigma chain	ADH7	0.0018
316	4-trimethylaminobutyraldehyde dehydrogenase	ALDH9A1	0.0018
337	NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial	NDUFS7	0.0018
214	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial	NDUFS3	0.0018
803	NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial	NDUFS2	0.0018
1144	Hepatocyte growth factor receptor	MET	0.0017
190	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4	NDUFA4	0.0017
300	NADH-ubiquinone oxidoreductase chain 4L	MT-ND4L	0.0017
374	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1	NDUFB1	0.0017
30	NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial	NDUFV3	0.0017
446	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7	NDUFA7	0.0017
525	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5	NDUFA5	0.0017
247	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	NDUFA1	0.0017
417	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6	NDUFB6	0.0017
324	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4	NDUFB4	0.0017
343	NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial	NDUFC1	0.0017
755	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3	NDUFA3	0.0017
353	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2	NDUFA4L2	0.0017
313	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3	NDUFB3	0.0017
384	NADH-ubiquinone oxidoreductase chain 6	MT-ND6	0.0017
607	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2	NDUFA2	0.0017
555	NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial	NDUFS4	0.0017
475	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial	NDUFB2	0.0017
99	NADH dehydrogenase [ubiquinone] iron-sulfur protein 5	NDUFS5	0.0017
270	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial	NDUFB5	0.0017
219	NADH-ubiquinone oxidoreductase chain 3	MT-ND3	0.0017
41	NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial	NDUFS8	0.0017
104	NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial	NDUFS6	0.0017
236	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6	NDUFA6	0.0017
568	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7	NDUFB7	0.0017
598	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11	NDUFA11	0.0017
582	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	NDUFA13	0.0017
829	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12	NDUFA12	0.0017
602	Acyl carrier protein, mitochondrial	NDUFAB1	0.0017
405	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8	NDUFA8	0.0017
272	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10	NDUFB10	0.0017
372	Estradiol 17-beta-dehydrogenase 3	HSD17B3	0.0017
644	Heme oxygenase 2	HMOX2	0.0017
4982	Heme oxygenase 2	pbsA2	0.0017
656	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9	NDUFB9	0.0017
729	GDP-L-fucose synthetase	TSTA3	0.0017
3463	GDP-L-fucose synthetase	fcl	0.0017
746	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial	NDUFB8	0.0017
167	L-lactate dehydrogenase C chain	LDHC	0.0017
326	L-lactate dehydrogenase A-like 6A	LDHAL6A	0.0017
141	3-hydroxyisobutyrate dehydrogenase, mitochondrial	HIBADH	0.0017
206	3-keto-steroid reductase	HSD17B7	0.0017
721	NADH-ubiquinone oxidoreductase chain 2	MT-ND2	0.0017
231	Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic	GPD1	0.0017
91	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial	NDUFA10	0.0017
14	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial	IDH3A	0.0017
112	L-lactate dehydrogenase A-like 6B	LDHAL6B	0.0017
9	Estradiol 17-beta-dehydrogenase 2	HSD17B2	0.0017
671	Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial	PDHA2	0.0017
628	Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial	PDHA1	0.0017
152	NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial	NDUFV2	0.0017
608	NADH-ubiquinone oxidoreductase chain 4	MT-ND4	0.0017
539	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial	NDUFV1	0.0017
496	Aldehyde dehydrogenase 3B1	ALDH3B1	0.0017
609	15-hydroxyprostaglandin dehydrogenase [NAD+]	HPGD	0.0017
662	Fatty aldehyde dehydrogenase	ALDH3A2	0.0017
711	UDP-glucose 6-dehydrogenase	UGDH	0.0017
3672	UDP-glucose 6-dehydrogenase	hasB	0.0017
149	Alpha-aminoadipic semialdehyde dehydrogenase	ALDH7A1	0.0017
145	Corticosteroid 11-beta-dehydrogenase isozyme 2	HSD11B2	0.0017
531	Aldehyde dehydrogenase X, mitochondrial	ALDH1B1	0.0017
107	C-4 methylsterol oxidase	SC4MOL	0.0017
180	D-3-phosphoglycerate dehydrogenase	PHGDH	0.0017
3726	D-3-phosphoglycerate dehydrogenase	serA	0.0017
4291	D-3-phosphoglycerate dehydrogenase	serA	0.0017
258	Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial	ALDH6A1	0.0017
271	Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial	ALDH4A1	0.0017
196	D-beta-hydroxybutyrate dehydrogenase, mitochondrial	BDH1	0.0017
50	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating	NSDHL	0.0017
335	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial	NDUFA9	0.0017
216	Aldehyde dehydrogenase 3B2	ALDH3B2	0.0017
616	Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial	IDH3B	0.0017
848	Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial	IDH3G	0.0017
643	Peroxisomal bifunctional enzyme	EHHADH	0.0017
288	Trifunctional enzyme subunit alpha, mitochondrial	HADHA	0.0017
637	NADH-ubiquinone oxidoreductase chain 5	MT-ND5	0.0017
393	GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase	H6PD	0.0017
34	7-dehydrocholesterol reductase	DHCR7	0.0017
3221	Cytochrome c4	cc4	0.0017
548	NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial	NDUFS1	0.0017
350	3-hydroxyacyl-CoA dehydrogenase type-2	HSD17B10	0.0017
178	NADH-cytochrome b5 reductase 3	CYB5R3	0.0017
812	Dihydrolipoyl dehydrogenase, mitochondrial	DLD	0.0017
454	Peroxisomal multifunctional enzyme type 2	HSD17B4	0.0017
2539	Tubulin alpha-1 chain	TUBA4A	0.0016
163	D(1B) dopamine receptor	DRD5	0.0016
363	NADP-dependent malic enzyme, mitochondrial	ME3	0.0016
328	Sorbitol dehydrogenase	SORD	0.0016
597	Dihydropteridine reductase	QDPR	0.0016
396	Alcohol dehydrogenase 4	ADH4	0.0016
896	Glutathione S-transferase Mu 1	GSTM1	0.0016
1524	Peptidyl-prolyl cis-trans isomerase A	PPIA	0.0016
6700	Peptidyl-prolyl cis-trans isomerase A	ppiA	0.0016
6824	Tyrosine-protein kinase Lyn	LYN	0.0016
6766	O-GlcNAcase BT_4395	BT_4395	0.0016
5300	Antigen peptide transporter 1	TAP1	0.0016
4948	Cytochrome c-553	Not Available	0.0016
4923	Cytochrome c3	DvMF_2499	0.0016
4945	Cytochrome c3	Not Available	0.0016
4949	Cytochrome c3	DVU_3171	0.0016
4968	Cytochrome c3	cytc3	0.0016
4997	Cytochrome c3	SO_2727	0.0016
5219	Cytochrome c3	cyd	0.0016
3189	High-molecular-weight cytochrome c	hmcA	0.0016
4902	Nine-heme cytochrome c	Ddes_2038	0.0016
839	Short-chain specific acyl-CoA dehydrogenase, mitochondrial	ACADS	0.0016
419	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	HADH	0.0016
77	L-lactate dehydrogenase B chain	LDHB	0.0016
12	Alcohol dehydrogenase class 3	ADH5	0.0015
1256	5-hydroxytryptamine 6 receptor	HTR6	0.0015
74	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial	DLAT	0.0015
4785	Ig gamma-1 chain C region	IGHG1	0.0015
599	Glyceraldehyde-3-phosphate dehydrogenase	GAPDH	0.0015
4426	Glyceraldehyde-3-phosphate dehydrogenase	gap	0.0015
4454	Glyceraldehyde-3-phosphate dehydrogenase	gap	0.0015
4489	Glyceraldehyde-3-phosphate dehydrogenase	gap	0.0015
2450	Tyrosine-protein kinase ITK/TSK	ITK	0.0015
473	L-lactate dehydrogenase A chain	LDHA	0.0015
794	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific	GAPDHS	0.0015
208	DNA-directed RNA polymerase beta' chain	rpoC	0.0015
5774	DNA-directed RNA polymerase beta' chain	rpoC	0.0015
469	Annexin A1	ANXA1	0.0015
1770	Phospholipase C	PLCL1	0.0015
2841	Phospholipase C	plc	0.0015
1759	85 kDa calcium-independent phospholipase A2	PLA2G6	0.0015
734	D1 dopamine receptor-interacting protein calcyon	CALY	0.0014
166	NAD-dependent malic enzyme, mitochondrial	ME2	0.0014
6098	Potassium voltage-gated channel subfamily D member 2	KCND2	0.0014
6099	Potassium voltage-gated channel subfamily D member 3	KCND3	0.0014
2129	Sucrase-isomaltase, intestinal	SI	0.0014
4373	Medium-chain-fatty-acid--CoA ligase	Not Available	0.0014
6100	BDNF/NT-3 growth factors receptor	NTRK2	0.0014
6026	Alcohol dehydrogenase 6	ADH6	0.0014
164	Histamine H4 receptor	HRH4	0.0014
233	Potassium channel subfamily K member 2	KCNK2	0.0014
13	Aminomethyltransferase, mitochondrial	AMT	0.0014
296	Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial	MTHFD2	0.0014
248	Pyrroline-5-carboxylate reductase 1	PYCR1	0.0014
802	Pyrroline-5-carboxylate reductase 2	PYCR2	0.0014
626	Cysteine dioxygenase type 1	CDO1	0.0014
627	11-cis retinol dehydrogenase	RDH5	0.0014
640	Aldehyde dehydrogenase 1A3	ALDH1A3	0.0014
937	Proto-oncogene tyrosine-protein kinase LCK	LCK	0.0014
2232	Interleukin-5	IL5	0.0014
1593	Mucin-2	MUC2	0.0014
4386	Hemoglobin-like protein HbN	glbN	0.0014
1630	Integrin beta-2	ITGB2	0.0013
976	Platelet glycoprotein IX	GP9	0.0013
564	Cellular retinoic acid-binding protein 1	CRABP1	0.0013
936	Ephrin type-A receptor 2	EPHA2	0.0013
1768	Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit	GNG2	0.0013
5251	Carbonyl reductase [NADPH] 1	CBR1	0.0013
1268	Neuropeptide S receptor	NPSR1	0.0013
1581	G protein-activated inward rectifier potassium channel 2	KCNJ6	0.0013
1571	G protein-activated inward rectifier potassium channel 1	KCNJ3	0.0013
4024	Mitochondrial glutamate carrier 2	SLC25A18	0.0013
4025	Mitochondrial glutamate carrier 1	SLC25A22	0.0013
1912	Excitatory amino acid transporter 1	SLC1A3	0.0013
4019	Excitatory amino acid transporter 4	SLC1A6	0.0013
922	Glutamate receptor 4	GRIA4	0.0013
4021	Probable glutamyl-tRNA synthetase, mitochondrial	EARS2	0.0013
4026	Aspartyl aminopeptidase	DNPEP	0.0013
4022	Glutamate--ammonia ligase domain-containing protein 1	LGSN	0.0013
4023	N-acetylglutamate synthase, mitochondrial	NAGS	0.0013
4016	Excitatory amino acid transporter 5	SLC1A7	0.0013
1047	Excitatory amino acid transporter 2	SLC1A2	0.0013
927	Metabotropic glutamate receptor 8	GRM8	0.0013
664	Glutamate decarboxylase 2	GAD2	0.0013
3890	Glutamate decarboxylase 2	GAD2	0.0013
4020	Glutamyl aminopeptidase	ENPEP	0.0013
4018	Glutamate receptor delta-2 subunit	GRID2	0.0013
915	Delta 1-pyrroline-5-carboxylate synthetase	ALDH18A1	0.0013
925	Metabotropic glutamate receptor 4	GRM4	0.0013
926	Metabotropic glutamate receptor 7	GRM7	0.0013
924	Glutamate receptor, ionotropic kainate 3	GRIK3	0.0013
919	Glutamate receptor, ionotropic kainate 4	GRIK4	0.0013
4027	Glutamate receptor delta-1 subunit	GRID1	0.0013
920	Glutamate receptor, ionotropic kainate 5	GRIK5	0.0013
4017	5-oxoprolinase	OPLAH	0.0013
4943	Cytochrome c6	petJ	0.0013
4954	Soluble cytochrome b558	Not Available	0.0013
4934	Cytochrome c-551	nirM	0.0013
5218	Cytochrome c-551	nirM	0.0013
4905	Cytochrome c2	Not Available	0.0013
4939	Cytochrome c2	cycA	0.0013
4964	Cytochrome c2	cycA	0.0013
4979	Cytochrome c2	cycA	0.0013
6673	Cytochrome c2	cycA	0.0013
4984	Neuroglobin	NGB	0.0013
4947	Bacterial hemoglobin	vhb	0.0013
4994	Hemoglobin-like protein HbO	glbO	0.0013
4916	Cyanoglobin	glbN	0.0013
4942	Diheme cytochrome c napB	napB	0.0013
4925	Cytochrome c-type protein SHP	shp	0.0013
4998	Hemoglobin-like protein yjbI	yjbI	0.0013
4915	Cytochrome c-550	psbV	0.0013
4959	Cytochrome c-550	psbV	0.0013
5216	Cytochrome c-550	psbV	0.0013
4975	Cytochrome c-556	RPA3973	0.0013
5000	HemO	hemO	0.0013
4961	Hemophore HasA	hasA	0.0013
4981	Iron-starvation protein PigA	pigA	0.0013
4936	Cytochrome c2 iso-2	Not Available	0.0013
4910	Cytoglobin	CYGB	0.0013
4909	CooA protein	cooA	0.0013
4904	Cytochrome c family protein	GSU1996	0.0013
4907	Cytochrome c-L	moxG	0.0013
6865	Cytochrome c-L	moxG	0.0013
4935	Cytochrome c-554	cycA1	0.0013
4976	Apocytochrome f	petA	0.0013
6407	Apocytochrome f	petA	0.0013
4971	Nonaheme cytochrome c	hmcA	0.0013
4937	Cytochrome oxidase subunit II	rcoxA	0.0013
4764	Cytochrome P450 165C4	CYP165C4	0.0013
4989	Cytochrome c551 peroxidase	ccp	0.0013
5222	Cytochrome c551 peroxidase	ccpA	0.0013
4931	Cytochrome P450 167A1	CYP167A1	0.0013
4926	Heme-based aerotactic transducer hemAT	hemAT	0.0013
4999	Cytochrome P450 165B3	CYP165B3	0.0013
4960	Putative cytochrome P450-family protein	SCO7417	0.0013
4972	P450cin	cinA	0.0013
4903	Methyl-accepting chemotaxis protein	Tar4	0.0013
4993	Hydroxylamine oxidoreductase	hao1	0.0013
4922	Cytochrome c, putative	SO_4144	0.0013
4952	Catalase/peroxidase	katA	0.0013
4970	Cytochrome c nitrite reductase catalytic subunit	nrfA	0.0013
3093	Catalase HPII	katE	0.0013
4908	Heme-regulated cyclic AMP phosphodiesterase	dosP	0.0013
859	Cellular retinoic acid-binding protein 2	CRABP2	0.0013
458	Neuronal acetylcholine receptor subunit alpha-10	CHRNA10	0.0013
814	Ryanodine receptor 1	RYR1	0.0013
4010	Mitochondrial dicarboxylate carrier	SLC25A10	0.0013
1410	Oxidoreductase	HSD17B6	0.0013
4725	Oxidoreductase	Not Available	0.0013
5124	Oxidoreductase	Not Available	0.0013
4007	Succinate receptor 1	SUCNR1	0.0013
4008	Succinyl-CoA:3-ketoacid-coenzyme A transferase 2, mitochondrial	OXCT2	0.0013
4002	Succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial	SUCLG1	0.0013
673	Solute carrier family 13 member 3	SLC13A3	0.0013
391	Succinyl-CoA ligase [GDP-forming] beta-chain, mitochondrial	SUCLG2	0.0013
4009	Succinyl-CoA ligase [ADP-forming] beta-chain, mitochondrial	SUCLA2	0.0013
498	Solute carrier family 13 member 2	SLC13A2	0.0013
25	Solute carrier family 13 member 1	SLC13A1	0.0013
84	Nuclear receptor 0B1	NR0B1	0.0013
57	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I	HSD3B1	0.0013
3087	Nicotinate-nucleotide adenylyltransferase	nadD	0.0013
4469	Nicotinate-nucleotide adenylyltransferase	nadD	0.0013
6893	Calcium/calmodulin-dependent protein kinase type II gamma chain	CAMK2G	0.0012
3856	Fibroblast growth factor receptor 3	FGFR3	0.0012
5590	N utilization substance protein B homolog	nusB	0.0012
5598	Glycerol uptake operon antiterminator-related protein	TM_1436	0.0012
5586	Pleckstrin homology domain-containing family A member 1	PLEKHA1	0.0012
5577	N5-carboxyaminoimidazole ribonucleotide mutase	purE	0.0012
3792	KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase	eda	0.0012
2838	Ribose-5-phosphate isomerase A	rpiA	0.0012
2952	Ribose-5-phosphate isomerase A	rpiA	0.0012
5595	Ribose-5-phosphate isomerase A	rpiA	0.0012
4695	UPF0124 protein yfiH	yfiH	0.0012
5060	Intron-associated endonuclease 1	ITEVIR	0.0012
5593	Transferase	Not Available	0.0012
5588	Cell division protein FtsY	TM_0570	0.0012
5591	Complement component C8 gamma chain	C8G	0.0012
5587	Iron(III)-binding periplasmic protein	fbpA	0.0012
5583	RNA 3'-terminal phosphate cyclase	rtcA	0.0012
5582	Regulator of transcription; stringent starvation protein A	sspA	0.0012
5592	Ribonucleoside-diphosphate reductase subunit beta	nrdF	0.0012
5581	Beta-fructosidase	bfrA	0.0012
5600	Pyruvate decarboxylase	pdc	0.0012
4375	Glutamine synthetase 1	glnA1	0.0012
5575	Short tail fiber protein	12	0.0012
5580	Hexon protein	PII	0.0012
5574	Invasin	YPTB1668	0.0012
694	Matrix protein 2	M	0.0012
625	Glutamate carboxypeptidase 2	FOLH1	0.0012
6073	Potassium channel subfamily K member 9	KCNK9	0.0012
6072	Potassium channel subfamily K member 3	KCNK3	0.0012
174	Sigma 1-type opioid receptor	SIGMAR1	0.0012
279	Tyrosinase	TYR	0.0012
3937	Fatty-acid amide hydrolase	FAAH	0.0012
6046	Voltage-gated calcium channel beta 1 subunit splice variant CavB1d	CACNB1	0.0012
461	Glycine receptor subunit alpha-3	GLRA3	0.0012
4003	Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial	OXCT1	0.0012
242	Asparagine synthetase [glutamine-hydrolyzing]	ASNS	0.0012
6859	Protein S100-A4	S100A4	0.0012
6048	Troponin C, skeletal muscle	TNNC2	0.0012
668	Glutamate--cysteine ligase regulatory subunit	GCLM	0.0012
714	Glutathione reductase, mitochondrial	GSR	0.0011
3991	Glutamine-dependent NAD(+) synthetase	NADSYN1	0.0011
3984	Probable glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial	PET112L	0.0011
5	Glutaminase liver isoform, mitochondrial	GLS2	0.0011
917	Glutaminase kidney isoform, mitochondrial	GLS	0.0011
355	GMP synthase [glutamine-hydrolyzing]	GMPS	0.0011
4353	GMP synthase [glutamine-hydrolyzing]	guaA	0.0011
3982	Phosphoribosylformylglycinamidine synthase	PFAS	0.0011
5261	Phosphoribosylformylglycinamidine synthase	purL	0.0011
2112	Toll-like receptor 9	TLR9	0.0011
4000	Prolyl 4-hydroxylase subunit alpha-2	P4HA2	0.0011
916	Metabotropic glutamate receptor 1	GRM1	0.0011
585	Aspartyl/asparaginyl beta-hydroxylase	ASPH	0.0011
665	Phosphoserine aminotransferase	PSAT1	0.0011
4652	Phosphoserine aminotransferase	serC	0.0011
801	Kynurenine/alpha-aminoadipate aminotransferase mitochondrial	AADAT	0.0011
3895	Kynurenine--oxoglutarate transaminase 3	CCBL2	0.0011
420	Glutamate decarboxylase 1	GAD1	0.0011
3900	Glutamate decarboxylase 1	GAD1	0.0011
6044	Serum paraoxonase/lactonase 3	PON3	0.0011
1467	Tumor necrosis factor ligand superfamily member 13B	TNFSF13B	0.0011
3940	Gamma-butyrobetaine dioxygenase	BBOX1	0.0011
97	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1	PLOD1	0.0011
3938	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3	PLOD3	0.0011
3964	Trimethyllysine dioxygenase, mitochondrial	TMLHE	0.0011
382	Glutamate receptor, ionotropic kainate 1	GRIK1	0.0011
3132	Tryptophan synthase alpha chain	trpA	0.0011
6568	Tryptophan synthase alpha chain	trpA	0.0011
923	Glutamate receptor 3	GRIA3	0.0011
5006	RNASE4 protein	RNASE4	0.0011
4006	Succinate dehydrogenase cytochrome b560 subunit, mitochondrial	SDHC	0.0011
4001	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial	SDHB	0.0011
2555	Pol polyprotein	pol	0.0011
3242	Pol polyprotein	gag-pol	0.0011
3471	Pol polyprotein	gag-pro-pol	0.0011
5256	Pol polyprotein	pol	0.0011
6469	Pol polyprotein	gag-pol	0.0011
6565	Pol polyprotein	Not Available	0.0011
3085	Molybdopterin-guanine dinucleotide biosynthesis protein A	mobA	0.0011
131	Synaptic vesicular amine transporter	SLC18A2	0.0011
4533	Glyoxalase family protein	BC_1747	0.0011
3729	Citrate synthase	gltA	0.0011
4575	Citrate synthase	cit	0.0011
4580	Citrate synthase	gltA	0.0011
5599	3-carboxy-cis,cis-muconate cycloisomerase	pcaB	0.0011
448	Vitamin K-dependent gamma-carboxylase	GGCX	0.001
1671	Excitatory amino acid transporter 3	SLC1A1	0.001
210	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase	EPRS	0.001
144	Hemoglobin subunit alpha	HBA1	0.001
186	Glutamate--cysteine ligase catalytic subunit	GCLC	0.001
572	Integrin alpha-L	ITGAL	0.001
3877	Growth-inhibiting protein 18	GIG18	0.001
5798	Mitogen-activated protein kinase 11	MAPK11	0.001
426	Aspartate aminotransferase, mitochondrial	GOT2	0.001
4366	Riboflavin kinase/FMN adenylyltransferase	TM_0857	0.001
914	Formimidoyltransferase-cyclodeaminase	FTCD	0.001
3949	Prolyl 3-hydroxylase 2	LEPREL1	0.001
3945	Prolyl 3-hydroxylase 1	LEPRE1	0.001
3951	Prolyl 3-hydroxylase 3	LEPREL2	0.001
563	Thyroid peroxidase	TPO	0.001
3999	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial	SDHD	0.001
4920	Peroxidase/catalase	katG	0.001
6079	Neuronal acetylcholine receptor subunit alpha-3	CHRNA3	0.001
197	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	SDHA	0.001
2603	Beta-lactamase II	blm	0.001
763	Tyrosine aminotransferase	TAT	0.001
5493	Tyrosine aminotransferase	Not Available	0.001
2521	Cell division protein ftsZ	ftsZ	0.001
3301	Cell division protein ftsZ	ftsZ	0.001
2473	Tyrosine-protein kinase CSK	CSK	0.001
2149	Angiogenin	ANG	0.001
2398	Tyrosine-protein kinase ZAP-70	ZAP70	0.001
735	Alanine aminotransferase 1	GPT	0.001
3904	Alanine aminotransferase 2	GPT2	0.001
586	Aspartate aminotransferase, cytoplasmic	GOT1	0.001
476	RAC-alpha serine/threonine-protein kinase	AKT1	0.001
3583	6-phosphogluconolactonase	pgl	0.001
2119	Cytochrome b5	CYB5A	0.001
890	Niemann-Pick C1-like protein 1	NPC1L1	0.001
4956	Quinohemoprotein alcohol dehydrogenase ADH IIB	qbdA	0.001
4037	Hypothetical protein	GPX1	0.001
4297	Hypothetical protein	SP_1951	0.001
4521	Hypothetical protein	BC_2969	0.001
4540	Hypothetical protein	TM_1070	0.001
4555	Hypothetical protein	MT1739	0.001
4569	Hypothetical protein	mshD	0.001
4578	Hypothetical protein	PA3270	0.001
4747	Hypothetical protein	PA3967	0.001
5177	Hypothetical protein	TM_0096	0.001
5194	Hypothetical protein	PA1204	0.001
5240	Hypothetical protein	Rv2991	0.001
5370	Hypothetical protein	TM_1158	0.001
5710	Hypothetical protein	Tb927.5.1360	0.001
4990	PpcA	ppcA	0.001
4289	Cytochrome P450	TT_P0059	0.001
6262	Cytochrome P450	staP	0.001
3570	Cytochrome P450 152A1	cypC	0.001
4988	Sulfite oxidase, mitochondrial	SUOX	0.001
2915	Sensor protein fixL	fixL	0.001
4944	Sensor protein fixL	fixL	0.001
3375	Acidic cytochrome c3	Not Available	0.001
67	Prolyl 4-hydroxylase subunit alpha-1	P4HA1	0.001
4385	Cytochrome c'	Not Available	0.001
4967	Cytochrome c'	cycA	0.001
5038	Cytochrome c'	Not Available	0.001
5223	Cytochrome c'	cycP	0.001
4813	Heme oxygenase	hmuO	0.001
5769	Heme oxygenase	Not Available	0.001
941	Betaine--homocysteine S-methyltransferase 1	BHMT	0.0009
2942	Sialidase	nanH	0.0009
3546	Sialidase	nedA	0.0009
3486	Fumarate hydratase class II	fumC	0.0009
2230	Catalase	CAT	0.0009
3249	Catalase	katA	0.0009
3625	Catalase	katA	0.0009
4539	Catalase	katA	0.0009
4941	Catalase	katB	0.0009
2869	1-deoxy-D-xylulose 5-phosphate reductoisomerase	dxr	0.0009
6933	Calcium-activated potassium channel subunit beta-4	KCNMB4	0.0009
6931	Calcium-activated potassium channel subunit beta-1	KCNMB1	0.0009
6932	Calcium-activated potassium channel subunit beta-3	KCNMB3	0.0009
6934	Small conductance calcium-activated potassium channel protein 1	KCNN1	0.0009
6935	Small conductance calcium-activated potassium channel protein 2	KCNN2	0.0009
6936	Small conductance calcium-activated potassium channel protein 3	KCNN3	0.0009
741	Potassium voltage-gated channel subfamily KQT member 1	KCNQ1	0.0009
990	Dual specificity mitogen-activated protein kinase kinase 1	MAP2K1	0.0009
6228	Nuclear receptor coactivator 1	NCOA1	0.0009
2452	Tryptophanyl-tRNA synthetase	trpS	0.0009
1341	Histamine H3 receptor	HRH3	0.0009
2697	Uridine-cytidine kinase 2	UCK2	0.0009
574	Branched-chain-amino-acid aminotransferase, cytosolic	BCAT1	0.0009
360	Ribonucleoside-diphosphate reductase large subunit	RRM1	0.0009
1569	G1/S-specific cyclin-D1	CCND1	0.0009
2240	Cell division protein kinase 2	CDK2	0.0009
2805	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1	HS3ST3A1	0.0009
1760	Aminopeptidase N	ANPEP	0.0009
6843	Aminopeptidase N	pepN	0.0009
2936	Oxygen-insensitive NAD(P)H nitroreductase	nfnB	0.0009
5184	Oxygen-insensitive NAD(P)H nitroreductase	nfnB	0.0009
411	Glycine N-methyltransferase	GNMT	0.0009
1262	Corticotropin-lipotropin	POMC	0.0009
3670	Soluble cytochrome b562 precursor	cybC	0.0009
3411	Cytochrome P450 121	cyp121	0.0009
117	Sterol O-acyltransferase 1	SOAT1	0.0008
1184	Interferon beta	IFNB1	0.0008
2617	Nitric oxide synthase oxygenase	nos	0.0008
2701	Nitric oxide synthase oxygenase	nos	0.0008
3291	Cytochrome c-552	cycA	0.0008
4927	Cytochrome c-552	nrfA	0.0008
4938	Cytochrome c-552	cycA	0.0008
4953	Cytochrome c-552	nrfA	0.0008
5217	Cytochrome c-552	cycM	0.0008
3102	Flavohemoprotein	hmp	0.0008
4969	Flavohemoprotein	hmp	0.0008
5579	Carboxypeptidase B	CPB1	0.0008
5463	Calcium-activated potassium channel subunit beta 2	KCNMB2	0.0008
6211	Tubulin epsilon chain	TUBE1	0.0008
6212	Tubulin gamma-1 chain	TUBG1	0.0008
6210	Tubulin delta chain	TUBD1	0.0008
3478	Glucose-1-phosphate thymidylyltransferase	rmlA	0.0008
4277	Glucose-1-phosphate thymidylyltransferase	rmlA	0.0008
3384	Macrophage migration inhibitory factor	MIF	0.0008
484	Tyrosine-protein kinase ABL2	ABL2	0.0008
606	Cytochrome P450 27, mitochondrial	CYP27A1	0.0008
128	Adenine phosphoribosyltransferase	APRT	0.0008
581	Cytochrome P450 2R1	CYP2R1	0.0008
2845	Bifunctional P-450:NADPH-P450 reductase	CYP102A1	0.0008
2530	Protein kinase C theta type	PRKCQ	0.0008
6038	Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	PDE6H	0.0008
2972	6-deoxyerythronolide B hydroxylase	eryF	0.0008
3610	Thioredoxin reductase 1, cytoplasmic	TXNRD1	0.0007
4608	Putative cytochrome P450	SCO1207	0.0007
4963	Putative cytochrome P450	SCO2884	0.0007
6254	Putative cytochrome P450	SCO6998	0.0007
215	Sodium channel protein type 11 subunit alpha	SCN11A	0.0007
6316	ADP-ribosylation factor 1	ARF1	0.0007
368	Enoyl-[acyl-carrier-protein] reductase [NADH]	inhA	0.0007
3228	Enoyl-[acyl-carrier-protein] reductase [NADH]	fabI	0.0007
3678	Enoyl-[acyl-carrier-protein] reductase [NADH]	fabI	0.0007
6856	Enoyl-[acyl-carrier-protein] reductase [NADH]	fabI	0.0007
6037	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	PDE6G	0.0007
4692	A/G-specific adenine glycosylase	mutY	0.0007
2511	MAP kinase-activated protein kinase 2	MAPKAPK2	0.0007
4666	Fucose-binding lectin PA-IIL	lecB	0.0007
358	Cystathionine beta-synthase	CBS	0.0007
2372	Bifunctional tail protein	9	0.0007
693	Hemoglobin subunit beta	HBB	0.0006
4878	Glycoprotein hormones alpha chain	CGA	0.0006
1052	Cytotoxic T-lymphocyte protein 4	CTLA4	0.0006
1072	Granzyme B	GZMB	0.0006
4871	Endo-beta-N-acetylglucosaminidase F3	endOF3	0.0006
4880	Membrane cofactor protein	CD46	0.0006
4889	Ig epsilon chain C region	IGHE	0.0006
4877	Beta-mannanase	man	0.0006
1563	Platelet glycoprotein Ib alpha chain	GP1BA	0.0006
4850	Beta-2-glycoprotein 1	APOH	0.0006
4856	CD209 antigen	CD209	0.0006
4189	Alpha-galactosidase A	GLA	0.0006
4869	Major capsid protein	A430L	0.0006
757	Fusion glycoprotein F0	F	0.0006
4875	Fusion glycoprotein F0	F	0.0006
4852	Reticulon-4 receptor	RTN4R	0.0006
4845	ADAM 33	ADAM33	0.0006
1354	Beta-glucuronidase	GUSB	0.0006
442	Envelope glycoprotein	gp41	0.0006
4859	Envelope glycoprotein	env	0.0006
4882	Dipeptidyl aminopeptidase-like protein 6	DPP6	0.0006
4721	Beta-1,4-mannanase	manA	0.0006
3352	Structural polyprotein	Not Available	0.0006
3628	Structural polyprotein	Not Available	0.0006
4892	Structural polyprotein	Not Available	0.0006
935	Proto-oncogene tyrosine-protein kinase Yes	YES1	0.0006
2216	Fibroblast growth factor receptor 4	FGFR4	0.0006
1063	Signal transducer and activator of transcription 5B	STAT5B	0.0006
2802	Endoglucanase G	celCCG	0.0006
6241	Nuclear receptor coactivator 2	NCOA2	0.0006
1176	Mitogen-activated protein kinase 1	MAPK1	0.0006
6268	Hydroxyacid oxidase 1	HAO1	0.0006
6164	POU domain, class 5, transcription factor 1	POU5F1	0.0006
719	Retinoic acid receptor responder protein 1	RARRES1	0.0006
770	Retinoic acid-induced protein 3	GPRC5A	0.0006
820	Glycine receptor subunit alpha-2	GLRA2	0.0006
934	Proto-oncogene tyrosine-protein kinase Fyn	FYN	0.0006
4193	Atrial natriuretic peptide clearance receptor	NPR3	0.0006
793	T-cell surface antigen CD2	CD2	0.0006
4861	Interleukin-6 receptor alpha chain	IL6R	0.0006
119	Carcinoembryonic antigen-related cell adhesion molecule 1	CEACAM1	0.0006
3837	Cytokine receptor common beta chain	CSF2RB	0.0006
5221	Cytochrome c3, 13 kDa	Not Available	0.0006
3152	Cytochrome c''	cycA	0.0006
5220	Split-Soret cytochrome c	Ddes_2150	0.0006
3700	Cytochrome c-552 precursor	nrfA	0.0006
856	Vitamin D3 receptor	VDR	0.0005
1721	Glycogen synthase kinase-3 beta	GSK3B	0.0005
2430	Chondroitinase B	cslB	0.0005
2298	Cytochrome P450-cam	camC	0.0005
3238	Multidrug resistance protein mexA	mexA	0.0005
3116	Bacterioferritin	bfr	0.0005
4906	Bacterioferritin	bfr	0.0005
4965	Bacterioferritin	bfr	0.0005
3173	Enolase	eno	0.0005
3709	Glycerol uptake facilitator protein	glpF	0.0005
3336	C4-dicarboxylate transport transcriptional regulatory protein dctD	dctD	0.0005
3393	TGF-beta receptor type-2	TGFBR2	0.0005
5489	Ribonucleoside-diphosphate reductase 1 subunit beta	nrdB	0.0005
6743	Non-fluorescent flavoprotein	luxF	0.0005
6753	Apolipoprotein M	APOM	0.0005
2528	Fatty acid metabolism regulator protein	fadR	0.0005
6740	Fatty acid metabolism regulator protein	fadR	0.0005
6752	Guanylyl cyclase-activating protein 1	GUCA1A	0.0005
394	Calcineurin subunit B isoform 1	PPP3R1	0.0005
6742	Recoverin	RCVRN	0.0005
6747	Chalcone/stilbene synthase family protein	MT1417	0.0005
6741	Peroxisomal 3,2-trans-enoyl-CoA isomerase	PECI	0.0005
6522	Hepatocyte nuclear factor 4-alpha	HNF4A	0.0005
6751	Gag polyprotein	gag	0.0005
6746	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	PPP3CA	0.0005
6749	Polyprotein	Not Available	0.0005
267	Plasminogen activator inhibitor 1	SERPINE1	0.0005
2427	Ferrichrome-iron receptor	fhuA	0.0005
1379	Interleukin-12 subunit beta	IL12B	0.0005
4890	Hemagglutinin	HA	0.0005
6566	Hemagglutinin	Not Available	0.0005
3127	Nitrite reductase	nirS	0.0005
3284	Nitrite reductase	nirS	0.0005
4857	Zinc-alpha-2-glycoprotein	AZGP1	0.0005
6858	Inactive carboxylesterase 4	CES1P1	0.0005
2852	DNA mismatch repair protein mutL	mutL	0.0005
5961	Insulin	INS	0.0005
760	Fibroblast growth factor 1	FGF1	0.0005
6120	Cation-independent mannose-6-phosphate receptor	IGF2R	0.0005
6221	Steroid hormone receptor ERR1	ESRRA	0.0005
5278	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1	PAPSS1	0.0005
6527	Lymphocyte antigen 96	LY96	0.0005
3191	Histidinol dehydrogenase	hisD	0.0005
18	High affinity immunoglobulin epsilon receptor subunit alpha	FCER1A	0.0005
554	Low-density lipoprotein receptor	LDLR	0.0004
852	Heparin cofactor 2	SERPIND1	0.0004
6172	ATP-binding cassette sub-family B member 8, mitochondrial	ABCB8	0.0004
4311	tRNA	TRDMT1	0.0004
4325	tRNA	trmD	0.0004
4328	tRNA	trmD	0.0004
3405	Quinohaemoprotein ethanol dehydrogenase type-1	qheDH	0.0004
1859	Prostatic acid phosphatase	ACPP	0.0004
6750	ADP-ribosylation factor 6	ARF6	0.0004
6524	Protein tonB	tonB	0.0004
3140	Hemagglutinin-neuraminidase	HN	0.0004
3609	Hemagglutinin-neuraminidase	HN	0.0004
3444	Cyanovirin-N	Not Available	0.0004
3258	Mannosyl-oligosaccharide alpha-1,2-mannosidase	MSDC	0.0004
1360	Sphingomyelin phosphodiesterase	SMPD1	0.0004
2435	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase	lpxC	0.0004
6613	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase	lpxC	0.0004
276	Sodium- and chloride-dependent GABA transporter 1	SLC6A1	0.0004
4509	Acetoin(diacetyl) reductase	budC	0.0004
340	Apoptotic protease-activating factor 1	APAF1	0.0004
6082	Neuronal acetylcholine receptor subunit beta-3	CHRNB3	0.0004
6080	Neuronal acetylcholine receptor subunit alpha-5	CHRNA5	0.0004
948	Neuronal acetylcholine receptor subunit beta-2	CHRNB2	0.0004
958	Insulin-like growth factor 1 receptor	IGF1R	0.0004
3689	Endoglucanase A	celA	0.0004
3009	Beta-glucanase	Not Available	0.0004
5411	Slt-IIvB	stxB2e	0.0004
5565	Inorganic polyphosphate/ATP-glucomannokinase	ppgmk	0.0004
5563	Galectin-2	LGALS2	0.0004
1875	Pulmonary surfactant-associated protein D	SFTPD	0.0004
5569	Endo-1,4-beta glucanase EngF	engF	0.0004
5046	Ecotin	eco	0.0004
3793	Aspartate ammonia-lyase	aspA	0.0004
5554	D-galactose-binding periplasmic protein	mglB	0.0004
3741	D-galactose-binding periplasmic protein precursor	mglB	0.0004
5568	Endoglucanase C307	celC307	0.0004
5553	Endoglucanase E1	Acel_0614	0.0004
5562	Hexokinase	Not Available	0.0004
3744	Endoglucanase SS precursor	celS	0.0004
5570	Endoglucanase E-4	celD	0.0004
5559	Neopullulanase	nplT	0.0004
4670	Cellulase B	celB	0.0004
4668	Laminarinase	TM_0024	0.0004
4667	BH0236 protein	BH0236	0.0004
4671	Endoglucanase C	cenC	0.0004
2577	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase	MAN1B1	0.0004
1243	Cathepsin D	CTSD	0.0003
6081	Neuronal acetylcholine receptor subunit alpha-6	CHRNA6	0.0003
864	Gag-Pol polyprotein	gag-pol	0.0003
2237	Gag-Pol polyprotein	gag-pol	0.0003
2326	Gag-Pol polyprotein	gag-pol	0.0003
2451	Gag-Pol polyprotein	gag-pol	0.0003
2901	Gag-Pol polyprotein	gag-pol	0.0003
3165	Gag-Pol polyprotein	gag-pol	0.0003
3722	Gag-Pol polyprotein	gag-pol	0.0003
6306	Gag-Pol polyprotein	gag-pol	0.0003
6624	Gag-Pol polyprotein	gag-pol	0.0003
2101	Glutathione-requiring prostaglandin D synthase	HPGDS	0.0003
825	Arsenical pump-driving ATPase	ASNA1	0.0003
3435	Arsenical pump-driving ATPase	arsA	0.0003
486	Serine/threonine-protein kinase ALS2CR7	CDK15	0.0003
2105	ATP-binding cassette sub-family G member 1	ABCG1	0.0003
377	Beta-adrenergic receptor kinase 1	ADRBK1	0.0003
510	Serine/threonine-protein kinase receptor R3	ACVRL1	0.0003
733	Activin receptor type 1B	ACVR1B	0.0003
225	NEDD8-activating enzyme E1 regulatory subunit	NAE1	0.0003
745	Anti-Muellerian hormone type-2 receptor	AMHR2	0.0003
483	A-Raf proto-oncogene serine/threonine-protein kinase	ARAF	0.0003
21	Beta-adrenergic receptor kinase 2	ADRBK2	0.0003
154	AFG3-like protein 2	AFG3L2	0.0003
395	ALK tyrosine kinase receptor	Not Available	0.0003
309	Antithrombin-III	SERPINC1	0.0003
1782	Neutrophil gelatinase-associated lipocalin	LCN2	0.0003
6078	Neuronal acetylcholine receptor subunit beta-4	CHRNB4	0.0003
5176	YtnJ	moxC	0.0003
5416	Coat protein VP1	Not Available	0.0003
2705	Dimethyl sulfoxide reductase	dmsA	0.0003
5247	Endo-1,4-beta-xylanase	Not Available	0.0003
5248	Endo-1,4-beta-xylanase	xlnA	0.0003
5250	Endo-1,4-beta-xylanase	xyl	0.0003
4669	Endo-1,4-beta-xylanase A	xynA	0.0003
4715	Endo-1,4-beta-xylanase A	xlnA	0.0003
5560	Endo-1,4-beta-xylanase A	xynA	0.0003
1503	Galectin-7	LGALS7	0.0003
5498	Maltoporin	lamB	0.0003
5561	Maltoporin	lamB	0.0003
5056	Maltooligosyltrehalose trehalohydrolase, putative	treZ	0.0003
3525	ADP-ribose pyrophosphatase, mitochondrial	NUDT9	0.0003
4622	Amylase	Not Available	0.0003
2728	Glucan 1,4-alpha-maltotetraohydrolase	amyP	0.0003
292	Activin receptor type-1	ACVR1	0.0003
849	Activated CDC42 kinase 1	TNK2	0.0003
6307	Ig gamma-2 chain C region	IGHG2	0.0003
2826	Glucose--fructose oxidoreductase	gfo	0.0003
1881	Hexokinase-1	HK1	0.0003
2581	Chondroitinase AC	cslA	0.0003
6847	Lactase-phlorizin hydrolase	LCT	0.0003
2324	Botulinum neurotoxin type B	botB	0.0003
704	Long-chain-fatty-acid--CoA ligase 1	ACSL1	0.0003
821	Acetyl-coenzyme A synthetase 2-like, mitochondrial	ACSS1	0.0003
386	Acetyl-coenzyme A synthetase, cytoplasmic	ACSS2	0.0003
297	Adenylate cyclase type 1	ADCY1	0.0003
289	Cytosolic purine 5'-nucleotidase	NT5C2	0.0003
3153	Quinoprotein glucose dehydrogenase-B	gdhB	0.0003
3747	Cellulase B precursor	celB	0.0003
3547	Enterotoxin type B	entB	0.0003
2856	Glucosamine-6-phosphate isomerase	GNPDA1	0.0003
2564	Glucan 1,4-alpha-maltohexaosidase	Not Available	0.0003
4819	Hydrolase	Not Available	0.0003
5249	Hydrolase	Not Available	0.0003
5436	Hydrolase	Not Available	0.0003
2531	Alpha-amylase	amyE	0.0003
2948	Alpha-amylase	amy	0.0003
3169	Alpha-amylase	Not Available	0.0003
2541	Neopullulanase 1	tvaI	0.0003
4811	Amylosucrase	ams	0.0003
3091	Maltodextrin phosphorylase	malP	0.0003
2606	Neopullulanase 2	tvaII	0.0003
6264	cAMP-dependent protein kinase inhibitor alpha	PKIA	0.0003
748	5'-AMP-activated protein kinase catalytic subunit alpha-1	PRKAA1	0.0003
3225	Shiga toxin B-chain	stxB	0.0003
3365	Beta-amylase	spoII	0.0003
4830	Aldose 1-epimerase	galM	0.0003
6614	Lactase-like protein	LCTL	0.0003
1675	Glucokinase	GCK	0.0003
4662	Glucokinase	glk	0.0003
3030	Salivary alpha-amylase	AMY1A	0.0003
2293	Cyclomaltodextrin glucanotransferase	Not Available	0.0003
2508	Cyclomaltodextrin glucanotransferase	cgt	0.0003
2523	Cyclomaltodextrin glucanotransferase	cgt	0.0003
3207	Cyclomaltodextrin glucanotransferase	amyA	0.0003
4272	POSSIBLE CELLULASE CELA1	celA1	0.0003
2570	Tetanus toxin	tetX	0.0002
2448	Exoglucanase/xylanase [Includes: Exoglucanase	cex	0.0002
3668	Maltose-binding periplasmic protein precursor	malE	0.0002
740	Argininosuccinate synthase	ASS1	0.0002
865	Argininosuccinate synthase	ASS1	0.0002
2680	Argininosuccinate synthase	argG	0.0002
3194	Argininosuccinate synthase	argG	0.0002
6021	Adenosine kinase	ADK	0.0002
2440	Endoglucanase F	celCCF	0.0002
2245	Xylose isomerase	xylA	0.0002
2253	Xylose isomerase	xylA	0.0002
2260	Xylose isomerase	xylA	0.0002
2431	Xylose isomerase	xylA	0.0002
2252	Endoglucanase 5A	cel5A	0.0002
10	Glycogen phosphorylase, liver form	PYGL	0.0002
2723	Cholera enterotoxin subunit B	ctxB	0.0002
4513	Pancreatic alpha-amylase	AMY2A	0.0002
1152	Glycogen phosphorylase, muscle form	PYGM	0.0002

(*) Categorization taken from DrugBank: therapeutic category or general category of a drug (i.e. anti-convulsant, antibacterial, etc.)

DB00936 - Salicyclic acid

Targets

Enzymes

Transporters

Carriers

Predictions