DT-Web

DB01171 - Moclobemide


Identification
Name Moclobemide
Accession Number DB01171 (APRD00603)
Type small molecule
Description A reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder.
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 268.739
Groups approved
Monoisotopic Weight 268.097855505
Pharmacology
Indication For the treatment of depression.
Mechanism of action The mechanism of action of moclobemide involves the selective, reversible inhibition of MAO-A. This inhibition leads to a decrease in the metabolism and destruction of monoamines in the neurotransmitters. This results in an increase in the monoamines, relieving depressive symptoms.
Absorption Well absorbed from the gastrointestinal tract (> 95%). The presence of food reduces the rate but not the extent of absorption. Hepatic first pass metabolism reduces bioavailability to 45-70% following administration of a single dose, but increases to 80% with multiple dosing as a result of saturation of the first pass effect. Peak plasma concentrations are reached within 1 - 2 hours following oral administration.
Protein binding Approximately 50% (primarily to albumin)
Biotransformation Moclobemide is almost completely metabolized in the liver by Cytochrome P450 2C19 and 2D6.
Route of elimination Not Available
Toxicity LD50 (mouse) is 730mg/kg and LD50 (rat) is 1,300mg/kg. Signs of toxicity include hypertension, drowsiness, dizziness, confusion, tremors, headache, agitation, muscle rigidity and seizures.
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions
Drug Mechanism of interaction
Amitriptyline Possible severe adverse reaction with this combination
Amoxapine Possible severe adverse reaction with this combination
Bezafibrate MAO Inhibitors may enhance the adverse/toxic effect of Bezafibrate. Avoid concomitant use of bezafibrate with monoamine oxidase inhibitors (MAOIs) like moclobemide.
Brimonidine MAO Inhibitors like moclobemide may enhance the hypertensive effect of Alpha2-Agonists (Ophthalmic). The concomitant use of monoamine oxidase inhibitors and ophthalmic alpha2 agonists is contraindicated.
Buprenorphine Buprenorphine may enhance the adverse/toxic effect of MAO Inhibitors like moclobemide. When possible, avoid use of buprenorphine in patients who have used a monoamine oxidase inhibitor within the past 14 days due to possible severe adverse effects.
Cimetidine Cimetidine may increase the serum concentration of moclobemide by decreasing its metabolism. Monitor for changes in the therapeutic and adverse effects of moclobemide if cimetidine is initiated, discontinued or dose changed.
Citalopram Possible serotoninergic syndrome
Clomipramine Possible severe adverse reaction with this combination
Desipramine Possible severe adverse reaction with this combination
Desvenlafaxine Increased risk of serotonin syndrome. Ensure adequate washout period between therapies to avoid toxicity. Concurrent therapy should be avoided.
Dextromethorphan Increased CNS toxicity
Dobutamine Moclobemide increases the sympathomimetic effect of dobutamine.
Donepezil Possible antagonism of action
Dopamine Moclobemide increases the sympathomimetic effect of dopamine.
Doxepin Possible severe adverse reaction with this combination
Ephedra Moclobemide increases the sympathomimetic effect of ephedra.
Ephedrine Moclobemide increases the sympathomimetic effect of ephedrine.
Epinephrine Moclobemide increases the sympathomimetic effect of epinephrine.
Fenoterol Moclobemide increases the sympathomimetic effect of fenoterol.
Fluoxetine Risk of serotoninergic syndrome
Fluvoxamine Increased incidence of adverse effects with this association
Galantamine Possible antagonism of action
Imipramine Possible severe adverse reaction with this combination
Isoproterenol Moclobemide increases the sympathomimetic effect of isoproterenol.
Meperidine Increased CNS toxicity (can cause death)
Mephentermine Moclobemide increases the sympathomimetic effect of mephentermine.
Metaraminol Moclobemide increases the sympathomimetic effect of metaraminol.
Methoxamine Moclobemide increases the sympathomimetic effect of methoxamine.
Milnacipran Increase serotonin levels. Combination therapy is contraindicated.
Norepinephrine Moclobemide increases the sympathomimetic effect of norepinephrine.
Nortriptyline Possible severe adverse reaction with this combination
Orciprenaline Moclobemide increases the sympathomimetic effect of orciprenaline.
Paroxetine Possible severe adverse reaction with this combination
Phenylephrine Moclobemide increases the sympathomimetic effect of phenylephrine.
Phenylpropanolamine Moclobemide increases the sympathomimetic effect of phenylpropanolamine.
Pirbuterol Moclobemide increases the sympathomimetic effect of pirbuterol.
Procaterol Moclobemide increases the sympathomimetic effect of procaterol.
Protriptyline Possible severe adverse reaction with this combination
Pseudoephedrine Moclobemide increases the sympathomimetic effect of pseudoephedrine.
Rivastigmine Possible antagonism of action
Rizatriptan The MAO inhibitor, moclobemide, may decrease the metabolism and clearance of the serotonin 5-HT receptor agonist, rizatriptan. Concomitant therapy is contraindicated.
Salbutamol Moclobemide increases the sympathomimetic effect of salbutamol.
Selegiline Decrease in selectivity
Sertraline Possible severe adverse reaction with this combination
Sibutramine Possible serotoninergic syndrome with this combination
Tacrine The therapeutic effects of the central acetylcholinesterase inhibitor, Tacrine, and/or the anticholinergic, Moclobemide, may be reduced due to antagonism. The interaction may be beneficial when the anticholinergic action is a side effect. Monitor for decreased efficacy of both agents.
Terbinafine Terbinafine may reduce the metabolism and clearance of Moclobemide. Consider alternate therapy or monitor for therapeutic/adverse effects of Moclobemide if Terbinafine is initiated, discontinued or dose changed.
Terbutaline Moclobemide increases the sympathomimetic effect of terbutaline.
Tetrabenazine Tetrabenazine may increase the adverse/toxic effects of Moclobemide. Concomitant therapy is contraindicated.
Ticlopidine Ticlopidine may decrease the metabolism and clearance of Moclobemide. Consider alternate therapy or monitor for adverse/toxic effects of Moclobemide if Ticlopidine is initiated, discontinued or dose changed.
Tolcapone Tolcapone and Moclobemide decrease the metabolism of endogenous catecholamines. Concomitant therapy may result in increased catecholamine effects. Consider alternate therapy or use cautiously and monitor for increased catecholamine effects.
Tramadol Tramadol may increase the risk of serotonin syndrome and seizure induction by the MAO inhibitor, moclobemide.
Tranylcypromine Increased risk of serotonin syndrome. Use caution during concomitant therapy and monitor for symptoms of serotonin syndrome.
Trazodone Increased risk of serotonin syndrome. Monitor for symptoms of serotonin syndrome.
Trimethobenzamide Trimethobenzamide and Moclobemide, two anticholinergics, may cause additive anticholinergic effects and enhance their adverse/toxic effects. Monitor for enhanced anticholinergic effects.
Trimipramine Increased risk of serotonin syndrome. Ensure adequate washout period between therapies to avoid toxicity. Avoid combination or monitor for symptoms of serotonin syndrome and/or hypertensive crisis.
Triprolidine Triprolidine and Moclobemide, two anticholinergics, may cause additive anticholinergic effects and enhance their adverse/toxic effects. Additive CNS depressant effects may also occur. Monitor for enhanced anticholinergic and CNS depressant effects.
Trospium Trospium and Moclobemide, two anticholinergics, may cause additive anticholinergic effects and enhanced adverse/toxic effects. Monitor for enhanced anticholinergic effects.
Tryptophanyl-5'amp Possible severe adverse reaction with this combination
Venlafaxine Increased risk of serotonin syndrome. Ensure adequate washout period between therapies to avoid toxicity. Concurrent therapy should be avoided.
Zolmitriptan The MAO inhibitor, moclobemide, may increase the serum concentration of zolmitriptan by decreasing its metabolism. Concomitant therapy and use of zolmitriptan within two weeks of discontinuing moclobemide are contraindicated.
Food Interactions
  • Food slows absorption a little. Avoid alcohol. Take after meals in order to minimize the risk of interaction with tyramine.

Targets


Amine oxidase [flavin-containing] A
Name Amine oxidase [flavin-containing] A
Gene Name MAOA
Pharmacological action yes
Actions inhibitor
References
  • Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. - Pubmed
  • Berlin I, Zimmer R, Thiede HM, Payan C, Hergueta T, Robin L, Puech AJ: Comparison of the monoamine oxidase inhibiting properties of two reversible and selective monoamine oxidase-A inhibitors moclobemide and toloxatone, and assessment of their effect on psychometric performance in healthy subjects. Br J Clin Pharmacol. 1990 Dec;30(6):805-16. - Pubmed
  • Fulton B, Benfield P: Moclobemide. An update of its pharmacological properties and therapeutic use. Drugs. 1996 Sep;52(3):450-74. - Pubmed
DTHybrid score 0.5688

Enzymes


Amine oxidase [flavin-containing] A
Name Amine oxidase [flavin-containing] A
Gene Name MAOA
Actions inhibitor
References
  • Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. - Pubmed
DTHybrid score 0.5688
Amine oxidase [flavin-containing] B
Name Amine oxidase [flavin-containing] B
Gene Name MAOB
Actions Not Available
References
  • -
  • Fisar Z, Hroudova J, Raboch J: Inhibition of monoamine oxidase activity by antidepressants and mood stabilizers. Neuro Endocrinol Lett. 2010;31(5):645-56. - Pubmed
DTHybrid score 0.9689
Cytochrome P450 2C19
Name Cytochrome P450 2C19
Gene Name CYP2C19
Actions substrate,inhibitor
References
  • Flockhart DA. - Drug Interactions: Cytochrome P450 Drug Interaction Table
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.3512
Cytochrome P450 2D6
Name Cytochrome P450 2D6
Gene Name CYP2D6
Actions substrate,inhibitor,inducer
References
  • Flockhart DA. - Drug Interactions: Cytochrome P450 Drug Interaction Table
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.4078
Cytochrome P450 1A2
Name Cytochrome P450 1A2
Gene Name CYP1A2
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.3911
Cytochrome P450 2C9
Name Cytochrome P450 2C9
Gene Name CYP2C9
Actions substrate,inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.3898

Predictions


Id Partner name Gene Name Score
4512 Cytochrome P450 3A4 CYP3A4 0.3023
4924 Cytochrome P450 2C8 CYP2C8 0.1729
1588 Multidrug resistance protein 1 ABCB1 0.1503
6030 Cytochrome P450 2B6 CYP2B6 0.1264
6013 Cytochrome P450 2E1 CYP2E1 0.125
4118 Cytochrome P450 3A5 CYP3A5 0.117
824 Sodium-dependent serotonin transporter SLC6A4 0.1088
6024 Cytochrome P450 1A1 CYP1A1 0.0884
6107 Cytochrome P450 3A7 CYP3A7 0.0882
713 Sodium-dependent dopamine transporter SLC6A3 0.088
5718 Cytochrome P450 2A6 CYP2A6 0.083
540 Sodium-dependent noradrenaline transporter SLC6A2 0.078
20 Prostaglandin G/H synthase 1 PTGS1 0.0686
587 Serum albumin ALB 0.0586
492 Histamine H1 receptor HRH1 0.0557
556 Alpha-1A adrenergic receptor ADRA1A 0.0538
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0526
318 Alpha-2A adrenergic receptor ADRA2A 0.0516
502 5-hydroxytryptamine 2A receptor HTR2A 0.0492
831 D(2) dopamine receptor DRD2 0.0463
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0462
885 5-hydroxytryptamine 1B receptor HTR1B 0.0445
193 Beta-1 adrenergic receptor ADRB1 0.0417
6106 Cytochrome P450 2C18 CYP2C18 0.0416
725 5-hydroxytryptamine 1D receptor HTR1D 0.041
131 Synaptic vesicular amine transporter SLC18A2 0.0401
766 Beta-2 adrenergic receptor ADRB2 0.04
3811 Cytochrome P450 19A1 CYP19A1 0.0397
6145 Solute carrier family 22 member 1 SLC22A1 0.0395
220 Sodium channel protein type 5 subunit alpha SCN5A 0.039
511 5-hydroxytryptamine 1F receptor HTR1F 0.0382
320 5-hydroxytryptamine 1A receptor HTR1A 0.0382
23 D(1A) dopamine receptor DRD1 0.0368
290 Prostaglandin G/H synthase 2 PTGS2 0.036
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0356
3810 Catechol O-methyltransferase COMT 0.035
1729 Solute carrier family 22 member 6 SLC22A6 0.0345
6144 Solute carrier family 22 member 2 SLC22A2 0.0343
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0322
118 Organic cation/carnitine transporter 2 SLC22A5 0.0319
590 5-hydroxytryptamine 2C receptor HTR2C 0.0297
632 Alpha-1B adrenergic receptor ADRA1B 0.029
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0288
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0279
146 Androgen receptor AR 0.0271
1898 Cytochrome P450 1B1 CYP1B1 0.0264
36 Insulin receptor INSR 0.0258
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0253
629 Alpha-2B adrenergic receptor ADRA2B 0.0249
862 Multidrug resistance-associated protein 1 ABCC1 0.0248
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.024
6147 Solute carrier family 22 member 3 SLC22A3 0.0238
2864 Penton protein PIII 0.0236
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0227
341 5-hydroxytryptamine 3 receptor HTR3A 0.0224
378 Alpha-2C adrenergic receptor ADRA2C 0.022
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0215
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0213
789 Alpha-1D adrenergic receptor ADRA1D 0.0211
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0206
5841 Insulin-like growth factor IB IGF1 0.0206
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0202
1757 Myeloperoxidase MPO 0.0201
638 D(3) dopamine receptor DRD3 0.0197
273 Apoptosis regulator Bcl-2 BCL2 0.0196
731 HIV-1 protease HIV-1 protease 0.0196
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0192
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0191
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0186
6031 Cytochrome P450 3A43 CYP3A43 0.0182
817 DNA topoisomerase 2-alpha TOP2A 0.0182
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.0178
847 Mu-type opioid receptor OPRM1 0.0175
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0169
6142 Solute carrier family 22 member 8 SLC22A8 0.0166
833 Organic cation/carnitine transporter 1 SLC22A4 0.0166
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0164
465 Calmodulin CALM1 0.0163
432 D(4) dopamine receptor DRD4 0.0162
260 Cytochrome P450 51 ERG11 0.016
761 Cytochrome P450 51 ERG11 0.016
3163 Cytochrome P450 51 cyp51 0.016
6143 Solute carrier family 22 member 7 SLC22A7 0.0155
2164 Multidrug resistance-associated protein 4 ABCC4 0.0153
136 Estrogen receptor ESR1 0.0152
696 Kappa-type opioid receptor OPRK1 0.0149
776 Bile salt export pump ABCB11 0.0149
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0148
467 Delta-type opioid receptor OPRD1 0.0148
436 5-hydroxytryptamine 2B receptor HTR2B 0.0147
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0146
1656 CYP2B protein CYP2B 0.0145
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0145
891 Dihydropteroate synthase folP 0.0144
5359 Dihydropteroate synthase folP 0.0144
7175 Dihydropteroate synthase sulI 0.0144
122 P2Y purinoceptor 12 P2RY12 0.0138
6014 Cytochrome P450 2A13 CYP2A13 0.0132
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0131
477 DNA topoisomerase 4 subunit A parC 0.0127
886 DNA topoisomerase 4 subunit A parC 0.0127
6226 DNA topoisomerase 4 subunit A parC 0.0127
163 D(1B) dopamine receptor DRD5 0.0127
468 Cytochrome P450 4A11 CYP4A11 0.0126
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0126
404 DNA gyrase subunit A gyrA 0.0125
6224 DNA gyrase subunit A gyrA 0.0125
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0124
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0123
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0123
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0123
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0123
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.012
1517 Beta-3 adrenergic receptor ADRB3 0.0118
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0117
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0116
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0115
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0114
1636 Trace amine-associated receptor 1 TAAR1 0.0112
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0112
70 Type-1 angiotensin II receptor AGTR1 0.0111
474 Acetylcholinesterase ACHE 0.011
571 Melatonin receptor type 1A MTNR1A 0.011
362 Melatonin receptor type 1B MTNR1B 0.011
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0108
3923 Cholinesterase BCHE 0.0107
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0106
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0105
5698 Riboflavin synthase alpha chain ribE 0.0105
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0104
408 Riboflavin kinase RFK 0.0101
6220 Aryl hydrocarbon receptor AHR 0.0101
124 Histamine H2 receptor HRH2 0.0099
777 Tumor necrosis factor TNF 0.0098
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0097
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0097
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0097
958 Insulin-like growth factor 1 receptor IGF1R 0.0097
6182 Cytochrome P450 2J2 CYP2J2 0.0097
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.0097
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0096
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0095
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0095
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0094
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0094
620 Bifunctional dihydrofolate reductase-thymidylate synthase Not Available 0.0091
3913 Glutamic acid decarboxylase GAD65 0.009
94 5-hydroxytryptamine 4 receptor HTR4 0.009
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.0089
592 Carbonic anhydrase 4 CA4 0.0085
1483 Membrane copper amine oxidase AOC3 0.0085
16 Adenosine A1 receptor ADORA1 0.0084
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0083
153 Dopamine beta-hydroxylase DBH 0.0083
1024 Solute carrier family 22 member 11 SLC22A11 0.0082
1178 Adenosine A2a receptor ADORA2A 0.008
380 Cytochrome P450 17A1 CYP17A1 0.008
295 Carbonic anhydrase 1 CA1 0.0079
3917 Methylenetetrahydrofolate reductase MTHFR 0.0079
442 Envelope glycoprotein gp41 0.0078
4859 Envelope glycoprotein env 0.0078
654 Flavin reductase BLVRB 0.0075
6126 Carbonic anhydrase 7 CA7 0.0073
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0073
735 Alanine aminotransferase 1 GPT 0.0073
3904 Alanine aminotransferase 2 GPT2 0.0073
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0072
716 5-hydroxytryptamine 7 receptor HTR7 0.0072
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0071
504 Mast/stem cell growth factor receptor KIT 0.0071
365 Dihydrofolate reductase DHFR 0.007
2381 Dihydrofolate reductase DFR1 0.007
2833 Dihydrofolate reductase Not Available 0.007
2931 Dihydrofolate reductase folA 0.007
3544 Dihydrofolate reductase folA 0.007
3682 Dihydrofolate reductase folA 0.007
6642 Dihydrofolate reductase folA 0.007
6756 Dihydrofolate reductase dfrA 0.007
49 Endothelin B receptor EDNRB 0.007
6102 Arylamine N-acetyltransferase 2 NAT2 0.007
6136 Multidrug resistance-associated protein 5 ABCC5 0.0068
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0067
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0067
844 Epidermal growth factor receptor EGFR 0.0067
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0067
578 Endothelin-1 receptor EDNRA 0.0066
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0066
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0066
6148 Multidrug resistance-associated protein 7 ABCC10 0.0065
407 Vascular endothelial growth factor receptor 2 KDR 0.0065
357 Carbonic anhydrase 2 CA2 0.0065
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0065
3947 Xanthine dehydrogenase/oxidase XDH 0.0064
6141 Sodium/bile acid cotransporter SLC10A1 0.0063
6137 Multidrug resistance-associated protein 6 ABCC6 0.0063
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0063
173 Toll-like receptor 7 TLR7 0.0063
133 Dihydropterate synthase sulI 0.0063
4120 NADPH--cytochrome P450 reductase POR 0.0063
565 Extracellular calcium-sensing receptor CASR 0.0062
4604 Liver carboxylesterase 1 CES1 0.0062
4116 Dihydropteroate synthetase Not Available 0.0062
26 Vascular endothelial growth factor receptor 3 FLT4 0.0061
1010 Cytochrome P450 51A1 CYP51A1 0.0061
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.006
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.006
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.006
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.006
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.006
756 Sex hormone-binding globulin SHBG 0.0059
694 Matrix protein 2 M 0.0059
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0059
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0059
427 Substance-P receptor TACR1 0.0059
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0059
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.0058
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0058
32 Vascular endothelial growth factor receptor 1 FLT1 0.0058
183 Vascular endothelial growth factor A VEGFA 0.0058
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0058
373 Transthyretin TTR 0.0058
4122 Histone deacetylase 2 HDAC2 0.0057
1256 5-hydroxytryptamine 6 receptor HTR6 0.0057
3876 Aromatic-L-amino-acid decarboxylase DDC 0.0057
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0056
80 Peroxisome proliferator-activated receptor alpha PPARA 0.0056
228 Beta platelet-derived growth factor receptor PDGFRB 0.0056
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.0056
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0055
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0054
871 Glucocorticoid receptor NR3C1 0.0054
528 5-hydroxytryptamine 1E receptor HTR1E 0.0054
921 Glutamate receptor 2 GRIA2 0.0053
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0053
714 Glutathione reductase, mitochondrial GSR 0.0052
161 Tubulin beta chain TUBB 0.0052
312 Tubulin beta chain TUB2 0.0052
811 Translocator protein TSPO 0.0052
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0051
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0051
215 Sodium channel protein type 11 subunit alpha SCN11A 0.005
482 Glycine receptor subunit alpha-1 GLRA1 0.005
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0049
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0049
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0049
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0049
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0049
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.0049
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.0049
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0049
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0049
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0048
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0048
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0048
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0048
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0048
869 Estrogen receptor beta ESR2 0.0047
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.0047
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.0046
518 Peroxidase/catalase T katG 0.0046
750 Voltage-dependent calcium channel gamma-1 subunit CACNG1 0.0046
6044 Serum paraoxonase/lactonase 3 PON3 0.0046
275 Arachidonate 5-lipoxygenase ALOX5 0.0046
1275 Estrogen sulfotransferase SULT1E1 0.0045
992 Protein tyrosine kinase 2 beta PTK2B 0.0045
527 Prostacyclin receptor PTGIR 0.0045
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0045
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.0045
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0044
6020 Aldehyde oxidase AOX1 0.0044
2112 Toll-like receptor 9 TLR9 0.0044
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0044
818 50S ribosomal protein L10 rplJ 0.0043
6432 Transporter snf 0.0043
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0043
6133 Sodium channel subunit beta-2 SCN2B 0.0043
6134 Sodium channel subunit beta-3 SCN3B 0.0043
6132 Sodium channel subunit beta-1 SCN1B 0.0043
6135 Sodium channel subunit beta-4 SCN4B 0.0043
6127 Carbonic anhydrase-related protein CA8 0.0043
6129 Carbonic anhydrase-related protein 11 CA11 0.0043
6128 Carbonic anhydrase-related protein 10 CA10 0.0043
563 Thyroid peroxidase TPO 0.0043
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0042
823 Fibroblast growth factor receptor 2 FGFR2 0.0042
614 Progesterone receptor PGR 0.0042
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0042
606 Cytochrome P450 27, mitochondrial CYP27A1 0.0041
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0041
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0041
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0041
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0041
4203 Histamine N-methyltransferase HNMT 0.004
634 Squalene monooxygenase SQLE 0.004
7196 Squalene monooxygenase ERG1 0.004
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.004
738 Monocarboxylate transporter 1 SLC16A1 0.004
6130 Carbonic anhydrase 13 CA13 0.004
1618 High affinity nerve growth factor receptor NTRK1 0.004
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0039
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0039
360 Ribonucleoside-diphosphate reductase large subunit RRM1 0.0039
4209 ATP-sensitive inward rectifier potassium channel 8 KCNJ8 0.0038
605 Fumarate reductase flavoprotein subunit frdA 0.0038
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0038
3673 Fumarate reductase flavoprotein subunit fccA 0.0038
4912 Fumarate reductase flavoprotein subunit ifcA 0.0038
6549 Fumarate reductase flavoprotein subunit frdA 0.0038
1629 Transcription factor AP-1 JUN 0.0038
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.0038
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.0037
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.0037
6085 Fatty acid-binding protein, intestinal FABP2 0.0037
130 Prostacyclin synthase PTGIS 0.0037
6146 High affinity copper uptake protein 1 SLC31A1 0.0036
6131 Carbonic anhydrase 14 CA14 0.0036
4228 Keratin, type II cytoskeletal 7 KRT7 0.0036
4311 tRNA TRDMT1 0.0036
4325 tRNA trmD 0.0036
4328 tRNA trmD 0.0036
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0035
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0035
5998 Toll-like receptor 8 TLR8 0.0035
6122 Carbonic anhydrase 3 CA3 0.0034
712 Tubulin alpha chain TUB1 0.0034
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.0034
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0034
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0034
174 Sigma 1-type opioid receptor SIGMAR1 0.0034
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0034
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0033
558 Solute carrier family 12 member 1 SLC12A1 0.0033
6506 Stathmin-4 STMN4 0.0033
327 Glutathione reductase gor 0.0033
5110 Glutathione reductase GR2 0.0033
613 Atrial natriuretic peptide receptor A NPR1 0.0033
1648 Elastin ELN 0.0032
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0032
1192 Sulfotransferase 1A1 SULT1A1 0.0032
459 Retinoic acid receptor RXR-alpha RXRA 0.0032
4205 Carbonic anhydrase 9 CA9 0.0031
3007 Carbonic anhydrase 12 CA12 0.0031
24 Thymidylate synthase TMP1 0.0031
359 Thymidylate synthase TYMS 0.0031
2626 Thymidylate synthase thyA 0.0031
2729 Thymidylate synthase thyA 0.0031
5352 Thymidylate synthase THYA 0.0031
1227 Cytochrome b MT-CYB 0.0031
6386 Cytochrome b petB 0.0031
6937 Cytochrome b MT-CYB 0.0031
674 Dihydroorotate dehydrogenase homolog, mitochondrial PFF0160c 0.0031
4199 Sphingosine 1-phosphate receptor Edg-8 S1PR5 0.0031
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.0031
780 Retinoic acid receptor RXR-gamma RXRG 0.003
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.003
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.003
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.003
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.003
33 Cystine/glutamate transporter SLC7A11 0.003
3957 Adenosine deaminase ADA 0.003
259 Microsomal triglyceride transfer protein large subunit MTTP 0.003
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.003
117 Sterol O-acyltransferase 1 SOAT1 0.003
621 Periplasmic [Fe] hydrogenase 1 Not Available 0.003
976 Platelet glycoprotein IX GP9 0.0029
54 Prothrombin F2 0.0029
4103 Proteasome subunit beta type 2 PSMB2 0.0029
4102 Proteasome subunit beta type 5 PSMB5 0.0029
4101 Proteasome subunit beta type 1 PSMB1 0.0029
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0029
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0029
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0028
208 DNA-directed RNA polymerase beta' chain rpoC 0.0028
5774 DNA-directed RNA polymerase beta' chain rpoC 0.0028
164 Histamine H4 receptor HRH4 0.0028
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0028
904 Glutathione S-transferase P GSTP1 0.0028
1200 AMBP protein AMBP 0.0028
3866 Serum amyloid A protein SAA1 0.0028
1932 Apolipoprotein E APOE 0.0028
88 Retinoic acid receptor RXR-beta RXRB 0.0027
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0027
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.0027
2159 Quinone oxidoreductase CRYZ 0.0027
284 DNA-directed RNA polymerase beta chain rpoB 0.0027
5773 DNA-directed RNA polymerase beta chain rpoB 0.0027
3849 Insulin-like growth factor-binding protein 7 IGFBP7 0.0027
2009 Protein NOV homolog NOV 0.0027
3847 Neuroendocrine convertase 2 PCSK2 0.0027
1949 Carboxypeptidase E CPE 0.0027
3850 Synaptotagmin-like protein 4 SYTL4 0.0027
3848 Neuroendocrine convertase 1 PCSK1 0.0027
3846 Retinoblastoma-associated protein RB1 0.0027
2981 Phospholipase A2, membrane associated PLA2G2A 0.0027
952 Dipeptidyl peptidase 4 DPP4 0.0026
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0026
6032 PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) fas 0.0026
790 DNA polymerase subunit alpha B POLA2 0.0026
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0026
85 Growth hormone receptor GHR 0.0025
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.0025
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0025
5880 Thrombopoietin receptor MPL 0.0025
241 Calcium-transporting ATPase type 2C member 1 ATP2C1 0.0025
3830 Calreticulin CALR 0.0025
1541 Metalloproteinase mmp20 0.0025
581 Cytochrome P450 2R1 CYP2R1 0.0025
239 Coagulation factor X F10 0.0024
1050 Bile salt sulfotransferase SULT2A1 0.0024
2300 Lysozyme E 0.0024
3633 Lysozyme R 0.0024
5597 Lysozyme 17 0.0024
106 Cannabinoid receptor 2 CNR2 0.0024
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0024
3639 Thymidine phosphorylase deoA 0.0024
3936 Thymidine phosphorylase TYMP 0.0024
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0024
6070 Nischarin NISCH 0.0024
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0024
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0024
537 ATP synthase delta chain, mitochondrial ATP5D 0.0024
6174 50S ribosomal protein L32 rpmF 0.0024
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.0023
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.0023
6034 Hydroxyindole O-methyltransferase ASMT 0.0023
6035 Nuclear receptor ROR-beta RORB 0.0023
6036 Eosinophil peroxidase EPX 0.0023
1196 Complement decay-accelerating factor CD55 0.0023
550 Amiloride-sensitive sodium channel subunit delta SCNN1D 0.0023
27 Amiloride-sensitive sodium channel subunit beta SCNN1B 0.0023
552 Amiloride-sensitive sodium channel subunit gamma SCNN1G 0.0023
213 Amiloride-sensitive sodium channel subunit alpha SCNN1A 0.0023
1992 Vitamin D-binding protein GC 0.0023
65 Matrix metalloproteinase-9 Not Available 0.0023
319 Opioid receptor, sigma 1 OPRS1 0.0023
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0023
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0023
68 Cannabinoid receptor 1 CNR1 0.0022
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0022
6068 Guanylate cyclase soluble subunit alpha-2 GUCY1A2 0.0022
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0022
2539 Tubulin alpha-1 chain TUBA4A 0.0022
1630 Integrin beta-2 ITGB2 0.0022
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0022
1864 RET proto-oncogene RET 0.0022
2155 Insulin-degrading enzyme IDE 0.0022
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0021
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0021
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0021
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0021
737 Mineralocorticoid receptor NR3C2 0.0021
1638 Solute carrier family 2, facilitated glucose transporter member 2 SLC2A2 0.0021
165 FL cytokine receptor FLT3 0.0021
1244 Low-density lipoprotein receptor-related protein 2 LRP2 0.0021
5300 Antigen peptide transporter 1 TAP1 0.0021
1374 Natriuretic peptides B NPPB 0.0021
63 Malate dehydrogenase mdh 0.0021
2329 Malate dehydrogenase mdh 0.0021
3445 Malate dehydrogenase mdh 0.0021
4420 Malate dehydrogenase mdh 0.0021
4438 Malate dehydrogenase mdh 0.0021
1827 Gap junction alpha-1 protein GJA1 0.0021
1908 Vascular cell adhesion protein 1 VCAM1 0.0021
6149 Solute carrier family 22 member 10 SLC22A10 0.0021
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.002
251 Alcohol dehydrogenase 1A ADH1A 0.002
765 Indoleamine 2,3-dioxygenase IDO1 0.002
7 Nitric oxide synthase, inducible NOS2 0.002
3090 Chitosanase csn 0.002
4149 Nuclear factor NF-kappa-B p100 subunit NFKB2 0.002
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.002
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.002
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.002
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.002
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.002
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.002
2808 Chloramphenicol acetyltransferase 3 cat3 0.002
1820 Beta-nerve growth factor NGF 0.002
814 Ryanodine receptor 1 RYR1 0.002
5878 Alpha-7 nicotinic cholinergic receptor subunit CHRFAM7A 0.002
5934 Cytochrome P450 26A1 CYP26A1 0.0019
3856 Fibroblast growth factor receptor 3 FGFR3 0.0019
6043 Putative G-protein coupled receptor 44 GPR44 0.0019
2449 Tubulin alpha-3 chain TUBA1A 0.0019
820 Glycine receptor subunit alpha-2 GLRA2 0.0019
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0019
512 DNA-directed RNA polymerase alpha chain rpoA 0.0019
5772 DNA-directed RNA polymerase alpha chain rpoA 0.0019
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.0019
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.0019
3808 Dihydropteroate synthase 2 folP2 0.0019
3601 Dihydropteroate synthase 1 folP1 0.0019
3807 Dihydropteroate synthase 1 folP1 0.0019
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.0019
2417 Chloramphenicol acetyltransferase cat 0.0018
3278 Chloramphenicol acetyltransferase cat 0.0018
893 [Citrate [pro-3S]-lyase] ligase citC 0.0018
845 Pyruvate dehydrogenase [cytochrome] poxB 0.0018
705 Glutamate receptor 1 GRIA1 0.0018
543 Penicillin-binding protein 1B mrcB 0.0018
6186 Penicillin-binding protein 1B ponB 0.0018
6822 Penicillin-binding protein 1b pbp1b 0.0018
6844 Penicillin-binding protein 1b pbp1b 0.0018
1253 Interferon gamma IFNG 0.0018
2810 Dr hemagglutinin structural subunit draA 0.0018
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0018
444 Alcohol dehydrogenase 1B ADH1B 0.0018
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0018
6766 O-GlcNAcase BT_4395 BT_4395 0.0018
645 Penicillin-binding protein 1A mrcA 0.0018
5805 Penicillin-binding protein 1A ponA 0.0018
6185 Penicillin-binding protein 1A mrcA 0.0018
6799 Penicillin-binding protein 1A pbpA 0.0018
159 Penicillin-binding protein 2B penA 0.0018
6121 Penicillin-binding protein 2B penA 0.0018
748 5'-AMP-activated protein kinase catalytic subunit alpha-1 PRKAA1 0.0018
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0018
3937 Fatty-acid amide hydrolase FAAH 0.0018
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.0018
4486 Phenol 2-hydroxylase component B pheA2 0.0018
4477 Dihydrolipoyl dehydrogenase lpdV 0.0018
5077 Dihydrolipoyl dehydrogenase Not Available 0.0018
5117 Dihydrolipoyl dehydrogenase lpd 0.0018
4439 Ferredoxin reductase bphA4 0.0018
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0018
5078 Amine oxidase, flavin-containing PSPTO1126 0.0018
526 Thioredoxin reductase trxB 0.0018
3767 Thioredoxin reductase trxB 0.0018
1341 Histamine H3 receptor HRH3 0.0018
5122 Mersacidin decarboxylase mrsD 0.0017
5095 Putidaredoxin reductase camA 0.0017
5107 Alkyl hydroperoxide reductase subunit F ahpF 0.0017
5118 Alkyl hydroperoxide reductase subunit F ahpF 0.0017
5114 Putative acyl-CoA dehydrogenase TT_C0779 0.0017
5109 Outer membrane protein p64k or PM-6 m-6 0.0017
5115 FkbI fkbI 0.0017
3133 UDP-galactopyranose mutase glf 0.0017
5099 UDP-galactopyranose mutase glf 0.0017
5097 PROBABLE DIHYDROLIPOAMIDE DEHYDROGENASE LPDA lpdA 0.0017
3763 5,10-methylenetetrahydrofolate reductase metF 0.0017
3918 5,10-methylenetetrahydrofolate reductase MTHFR 0.0017
5094 5,10-methylenetetrahydrofolate reductase metF 0.0017
5102 4-cresol dehydrogenase [hydroxylating] flavoprotein subunit pchF 0.0017
5111 Phenylacetone monooxygenase pamO 0.0017
1329 Apoptosis-inducing factor 1, mitochondrial AIFM1 0.0017
5083 Cryptochrome DASH cry 0.0017
5100 Gamma-aminobutyrate metabolism dehydratase/isomerase abfD 0.0017
5081 L-aspartate oxidase nadB 0.0017
1410 Oxidoreductase HSD17B6 0.0017
4725 Oxidoreductase Not Available 0.0017
5124 Oxidoreductase Not Available 0.0017
5112 Benzoate 1,2-dioxygenase electron transfer component benC 0.0017
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0017
268 Adenosine A2b receptor ADORA2B 0.0017
84 Nuclear receptor 0B1 NR0B1 0.0017
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0017
856 Vitamin D3 receptor VDR 0.0017
828 Phenylalanine-4-hydroxylase PAH 0.0017
3109 Phenylalanine-4-hydroxylase phhA 0.0017
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0017
1144 Hepatocyte growth factor receptor MET 0.0017
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0017
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0017
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0016
572 Integrin alpha-L ITGAL 0.0016
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0016
3102 Flavohemoprotein hmp 0.0016
4969 Flavohemoprotein hmp 0.0016
1830 5'-nucleotidase NT5E 0.0016
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0016
633 Penicillin-binding proteins 1A/1B pbpA 0.0016
390 Adenosine A3 receptor ADORA3 0.0016
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0016
6100 BDNF/NT-3 growth factors receptor NTRK2 0.0016
1243 Cathepsin D CTSD 0.0016
517 Alcohol dehydrogenase 1C ADH1C 0.0016
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0015
2853 14 kDa fatty acid-binding protein Not Available 0.0015
4440 NADH peroxidase npr 0.0015
5091 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0015
5093 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0015
3594 Deoxyribodipyrimidine photo-lyase phr 0.0015
5079 Deoxyribodipyrimidine photo-lyase phrB 0.0015
5080 Deoxyribodipyrimidine photo-lyase phr 0.0015
5072 N,N-dimethylglycine oxidase dmg 0.0015
2470 Pyruvate oxidase pox5 0.0015
5073 Ferredoxin--NADP reductase petH 0.0015
5076 Ferredoxin--NADP reductase fpr 0.0015
5119 Ferredoxin--NADP reductase petH 0.0015
5121 Ferredoxin--NADP reductase fpr 0.0015
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0015
440 Isovaleryl-CoA dehydrogenase, mitochondrial IVD 0.0015
667 Acyl-CoA dehydrogenase family member 8, mitochondrial ACAD8 0.0015
3506 Glutaryl-CoA dehydrogenase, mitochondrial GCDH 0.0015
5003 Acyl-CoA dehydrogenase, short-chain specific Not Available 0.0015
2268 Cholesterol oxidase choB 0.0015
2822 Cholesterol oxidase choA 0.0015
982 Cocaine- and amphetamine-regulated transcript protein CARTPT 0.0015
2526 NADPH-ferredoxin reductase fprA fprA 0.0015
6639 Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 0.0015
3247 2-oxopropyl-CoM reductase, carboxylating xecC 0.0015
936 Ephrin type-A receptor 2 EPHA2 0.0015
2207 Rhodopsin RHO 0.0015
1039 Histone deacetylase 9 HDAC9 0.0015
6689 TraN protein traN 0.0015
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0015
6672 Destrin DSTN 0.0015
6680 Cofilin-1 CFL1 0.0015
6670 Ig kappa chain V-I region Bi Not Available 0.0015
3809 Estrogen-related receptor gamma ESRRG 0.0015
6671 Ig heavy chain V-III region VH26 Not Available 0.0015
2499 Tubulin beta-2C chain TUBB2C 0.0015
6688 TraF protein traF 0.0015
6404 Rhomboid protease glpG glpG 0.0015
6797 Rhomboid protease glpG glpG 0.0015
3710 Acyl-CoA thioesterase 2 tesB 0.0015
6685 Outer membrane protein II porB 0.0015
6690 BenF-like porin PFL_1329 0.0015
6681 Probable N-acetylneuraminic acid outer membrane channel protein nanC nanC 0.0015
6687 TraO protein traO 0.0015
5793 Cytochrome c oxidase subunit 2 MT-CO2 0.0015
6559 Cytochrome c oxidase subunit 2 ctaC 0.0015
6669 Cytochrome c oxidase subunit 2 ctaC 0.0015
6668 Cytochrome c oxidase subunit 1-beta ctaDII 0.0015
6679 Colicin-Ia cia 0.0015
6676 Fe(3+)-pyochelin receptor fptA 0.0015
115 Penicillin-binding protein 2 mrdA 0.0015
6069 Penicillin-binding protein 2 mrdA 0.0015
6118 Penicillin-binding protein 2 penA 0.0015
6187 Penicillin-binding protein 2 pbpA 0.0015
6686 Penicillin-binding protein 2 pbp2 0.0015
6939 Penicillin-binding protein 2 mrdA 0.0015
7163 Penicillin-binding protein 2 pbpA 0.0015
6674 Nuclear factor erythroid 2-related factor 1 NFE2L1 0.0015
3844 HLA class II histocompatibility antigen, DQ(6) alpha chain HLA-DQA2 0.0015
4217 Telomerase reverse transcriptase TERT 0.0015
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0015
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0015
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0015
3611 Cytidine deaminase cdd 0.0014
3707 Cytidine deaminase cdd 0.0014
4211 Cytidine deaminase CDA 0.0014
4773 Deoxycytidine kinase DCK 0.0014
3086 Plasmepsin-2 Not Available 0.0014
126 D-lactate dehydrogenase dld 0.0014
3545 D-lactate dehydrogenase Not Available 0.0014
4510 D-lactate dehydrogenase ldhA 0.0014
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0014
1360 Sphingomyelin phosphodiesterase SMPD1 0.0014
4226 Uridine phosphorylase 2 UPP2 0.0014
3185 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM 0.0014
3254 Bifunctional protein putA [Includes: Proline dehydrogenase putA 0.0014
2893 Glycine oxidase thiO 0.0014
2091 Endoplasmin HSP90B1 0.0014
6859 Protein S100-A4 S100A4 0.0014
908 Glutathione S-transferase theta-1 GSTT1 0.0014
4148 Serine/threonine-protein kinase mTOR MTOR 0.0014
751 Potassium channel subfamily K member 6 KCNK6 0.0014
2232 Interleukin-5 IL5 0.0014
1593 Mucin-2 MUC2 0.0014
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0013
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0013
3404 Exotoxin A eta 0.0013
2567 Thymidylate synthase thyX thyX 0.0013
2823 Trypanothione reductase TPR 0.0013
2769 P-hydroxybenzoate hydroxylase pobA 0.0013
2809 P-hydroxybenzoate hydroxylase pobA 0.0013
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0013
5787 Angiopoietin-1 receptor TEK 0.0013
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0013
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0013
4760 Mll3241 protein mll3241 0.0013
3395 Iron(III) dicitrate transport protein fecA fecA 0.0013
6385 H subunit of photosynthetic reaction center complex puhA 0.0013
6474 Outer membrane protein W ompW 0.0013
6678 Colicin I receptor cirA 0.0013
3578 Protein crcA crcA 0.0013
6675 Colicin-E3 ceaC 0.0013
2925 Long-chain fatty acid transport protein fadL 0.0013
6480 Outer membrane usher protein papC papC 0.0013
6438 Outer membrane protein G ompG 0.0013
2447 Ammonia channel amtB 0.0013
4225 Uridine phosphorylase 1 UPP1 0.0013
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0013
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0013
3426 Glutamine synthetase glnA 0.0013
3987 Glutamine synthetase GLUL 0.0013
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0013
860 Nicotinamide N-methyltransferase NNMT 0.0013
5626 Nucleoside diphosphate kinase B NME2 0.0013
699 Nicotinic acid receptor 1 GPR109A 0.0013
928 Nicotinic acid receptor 2 GPR109B 0.0013
583 Nicotinate-nucleotide pyrophosphorylase [carboxylating] QPRT 0.0013
2442 Nicotinate-nucleotide pyrophosphorylase [carboxylating] nadC 0.0013
2459 Nicotinate-nucleotide pyrophosphorylase [carboxylating] nadC 0.0013
6103 Arylamine N-acetyltransferase 1 NAT1 0.0013
172 Potassium channel subfamily K member 1 KCNK1 0.0012
291 Nitric-oxide synthase, endothelial NOS3 0.0012
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0012
2021 Thrombomodulin THBD 0.0012
76 Nitric-oxide synthase, brain NOS1 0.0012
232 Corticosteroid-binding globulin SERPINA6 0.0012
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0012
2380 Monomeric sarcosine oxidase soxA 0.0012
413 Amidophosphoribosyltransferase PPAT 0.0012
2515 Amidophosphoribosyltransferase purF 0.0012
3714 Amidophosphoribosyltransferase purF 0.0012
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0012
6645 D-amino-acid oxidase DAO 0.0012
162 Retinoic acid receptor gamma-1 RARG 0.0012
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0012
6428 Light-harvesting protein B-800/850 beta chain Not Available 0.0012
6427 Light-harvesting protein B-800/850 alpha chain Not Available 0.0012
6533 Light-harvesting protein B-800/850 alpha chain A1 0.0012
6524 Protein tonB tonB 0.0012
2679 Vitamin B12 transporter btuB btuB 0.0012
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0012
29 Tubulin beta-1 chain TUBB1 0.0012
473 L-lactate dehydrogenase A chain LDHA 0.0011
6048 Troponin C, skeletal muscle TNNC2 0.0011
5798 Mitogen-activated protein kinase 11 MAPK11 0.0011
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0011
2320 Thymidine kinase, cytosolic TK1 0.0011
469 Annexin A1 ANXA1 0.0011
267 Plasminogen activator inhibitor 1 SERPINE1 0.0011
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0011
6677 Myelin P2 protein PMP2 0.0011
4238 50S ribosomal protein L4 rplD 0.0011
5578 50S ribosomal protein L4 rplD 0.0011
6173 50S ribosomal protein L4 rplD 0.0011
6219 50S ribosomal protein L4 rplD 0.0011
1123 Eosinophil cationic protein RNASE3 0.0011
707 72 kDa type IV collagenase MMP2 0.0011
2183 Fatty acid-binding protein, adipocyte FABP4 0.0011
4192 DNA topoisomerase 2-beta TOP2B 0.0011
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0011
2290 ADP-ribosyl cyclase 2 BST1 0.001
6033 High affinity interleukin-8 receptor A CXCR1 0.001
4237 50S ribosomal protein L22 rplV 0.001
6218 Pannexin-1 PANX1 0.001
1714 Mitogen-activated protein kinase 3 MAPK3 0.001
6221 Steroid hormone receptor ERR1 ESRRA 0.001
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.001
5294 Nucleoside diphosphate kinase A NME1 0.001
6138 Multidrug resistance protein 3 ABCB4 0.001
144 Hemoglobin subunit alpha HBA1 0.001
6352 Reaction center protein H chain puhA 0.001
6456 Reaction center protein H chain puhA 0.001
6682 Reaction center protein H chain puhA 0.001
6353 Reaction center protein L chain pufL 0.001
6454 Reaction center protein L chain pufL 0.001
6683 Reaction center protein L chain pufL 0.001
6354 Reaction center protein M chain pufM 0.001
6455 Reaction center protein M chain pufM 0.001
6684 Reaction center protein M chain pufM 0.001
6351 Photosynthetic reaction center cytochrome c subunit pufC 0.001
6163 Copper-transporting ATPase 2 ATP7B 0.001
6165 Copper-transporting ATPase 1 ATP7A 0.001
760 Fibroblast growth factor 1 FGF1 0.001
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.001
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0009
2828 Squalene--hopene cyclase shc 0.0009
3126 Poly [ADP-ribose] polymerase 1 PARP1 0.0009
229 Retinoic acid receptor beta RARB 0.0009
1064 DNA (cytosine-5)-methyltransferase 1 DNMT1 0.0009
1768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit GNG2 0.0009
1268 Neuropeptide S receptor NPSR1 0.0009
1581 G protein-activated inward rectifier potassium channel 2 KCNJ6 0.0009
1571 G protein-activated inward rectifier potassium channel 1 KCNJ3 0.0009
730 Retinoic acid receptor alpha RARA 0.0009
741 Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 0.0009
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0009
6042 Prostaglandin reductase 2 PTGR2 0.0009
1262 Corticotropin-lipotropin POMC 0.0008
1792 Tissue-type plasminogen activator PLAT 0.0008
2236 Casein kinase II subunit alpha CSNK2A1 0.0008
3932 Glutathione S-transferase A2 GSTA2 0.0008
6073 Potassium channel subfamily K member 9 KCNK9 0.0008
6072 Potassium channel subfamily K member 3 KCNK3 0.0008
6167 Organic solute transporter subunit beta OSTB 0.0008
6166 Organic solute transporter subunit alpha OSTA 0.0008
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0008
244 Angiotensin-converting enzyme ACE 0.0008
6212 Tubulin gamma-1 chain TUBG1 0.0008
6210 Tubulin delta chain TUBD1 0.0008
6211 Tubulin epsilon chain TUBE1 0.0008
896 Glutathione S-transferase Mu 1 GSTM1 0.0008
500 Monocarboxylate transporter 4 SLC16A3 0.0008
400 Coagulation factor IX F9 0.0008
5461 Coagulation factor IX F9 0.0008
1063 Signal transducer and activator of transcription 5B STAT5B 0.0007
935 Proto-oncogene tyrosine-protein kinase Yes YES1 0.0007
866 Large neutral amino acids transporter small subunit 2 SLC7A8 0.0007
4948 Cytochrome c-553 Not Available 0.0007
4923 Cytochrome c3 DvMF_2499 0.0007
4945 Cytochrome c3 Not Available 0.0007
4949 Cytochrome c3 DVU_3171 0.0007
4968 Cytochrome c3 cytc3 0.0007
4997 Cytochrome c3 SO_2727 0.0007
5219 Cytochrome c3 cyd 0.0007
4902 Nine-heme cytochrome c Ddes_2038 0.0007
3189 High-molecular-weight cytochrome c hmcA 0.0007
822 Aldose reductase AKR1B1 0.0007
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0007
4081 Vitamin K epoxide reductase complex subunit 1-like protein 1 VKORC1L1 0.0007
604 Vitamin K-dependent protein Z PROZ 0.0007
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0007
6228 Nuclear receptor coactivator 1 NCOA1 0.0007
6241 Nuclear receptor coactivator 2 NCOA2 0.0007
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.0007
1313 Lactoylglutathione lyase GLO1 0.0007
934 Proto-oncogene tyrosine-protein kinase Fyn FYN 0.0006
489 Monocarboxylate transporter 2 SLC16A7 0.0006
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0006
1245 Vitamin K-dependent protein S PROS1 0.0006
422 Vitamin K-dependent protein C PROC 0.0006
4386 Hemoglobin-like protein HbN glbN 0.0006
2216 Fibroblast growth factor receptor 4 FGFR4 0.0006
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0006
484 Tyrosine-protein kinase ABL2 ABL2 0.0006
719 Retinoic acid receptor responder protein 1 RARRES1 0.0006
770 Retinoic acid-induced protein 3 GPRC5A 0.0006
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0006
3221 Cytochrome c4 cc4 0.0006
5221 Cytochrome c3, 13 kDa Not Available 0.0006
3152 Cytochrome c'' cycA 0.0006
5220 Split-Soret cytochrome c Ddes_2150 0.0006
3700 Cytochrome c-552 precursor nrfA 0.0006
5924 Microtubule-associated protein 4 MAP4 0.0005
5923 Microtubule-associated protein tau MAPT 0.0005
798 Osteocalcin BGLAP 0.0005
569 Retinal dehydrogenase 2 ALDH1A2 0.0005
6151 Monocarboxylate transporter 10 SLC16A10 0.0005
1852 Microtubule-associated protein 2 MAP2 0.0005
276 Sodium- and chloride-dependent GABA transporter 1 SLC6A1 0.0005
611 Retinal dehydrogenase 1 ALDH1A1 0.0005
3127 Nitrite reductase nirS 0.0005
3284 Nitrite reductase nirS 0.0005
1507 Cytochrome c CYCS 0.0005
6002 Prostaglandin E2 receptor EP4 subtype PTGER4 0.0005
369 Coagulation factor VII F7 0.0005
233 Potassium channel subfamily K member 2 KCNK2 0.0005
6824 Tyrosine-protein kinase Lyn LYN 0.0005
4131 Prostaglandin E2 receptor, EP3 subtype PTGER3 0.0004
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0004
406 Prostaglandin E2 receptor, EP2 subtype PTGER2 0.0004
3405 Quinohaemoprotein ethanol dehydrogenase type-1 qheDH 0.0004
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0004
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0004
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0004
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0004
6168 Solute carrier family 22 member 16 SLC22A16 0.0003
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0003
4954 Soluble cytochrome b558 Not Available 0.0002
4916 Cyanoglobin glbN 0.0002
4934 Cytochrome c-551 nirM 0.0002
5218 Cytochrome c-551 nirM 0.0002
4947 Bacterial hemoglobin vhb 0.0002
4915 Cytochrome c-550 psbV 0.0002
4959 Cytochrome c-550 psbV 0.0002
5216 Cytochrome c-550 psbV 0.0002
4925 Cytochrome c-type protein SHP shp 0.0002
4998 Hemoglobin-like protein yjbI yjbI 0.0002
4905 Cytochrome c2 Not Available 0.0002
4939 Cytochrome c2 cycA 0.0002
4964 Cytochrome c2 cycA 0.0002
4979 Cytochrome c2 cycA 0.0002
6673 Cytochrome c2 cycA 0.0002
5000 HemO hemO 0.0002
4975 Cytochrome c-556 RPA3973 0.0002
4984 Neuroglobin NGB 0.0002
4943 Cytochrome c6 petJ 0.0002
4910 Cytoglobin CYGB 0.0002
4907 Cytochrome c-L moxG 0.0002
6865 Cytochrome c-L moxG 0.0002
4981 Iron-starvation protein PigA pigA 0.0002
4971 Nonaheme cytochrome c hmcA 0.0002
4936 Cytochrome c2 iso-2 Not Available 0.0002
4909 CooA protein cooA 0.0002
4994 Hemoglobin-like protein HbO glbO 0.0002
4935 Cytochrome c-554 cycA1 0.0002
644 Heme oxygenase 2 HMOX2 0.0002
4982 Heme oxygenase 2 pbsA2 0.0002
4942 Diheme cytochrome c napB napB 0.0002
3116 Bacterioferritin bfr 0.0002
4906 Bacterioferritin bfr 0.0002
4965 Bacterioferritin bfr 0.0002
4922 Cytochrome c, putative SO_4144 0.0002
4764 Cytochrome P450 165C4 CYP165C4 0.0002
4937 Cytochrome oxidase subunit II rcoxA 0.0002
4989 Cytochrome c551 peroxidase ccp 0.0002
5222 Cytochrome c551 peroxidase ccpA 0.0002
4961 Hemophore HasA hasA 0.0002
4976 Apocytochrome f petA 0.0002
6407 Apocytochrome f petA 0.0002
4904 Cytochrome c family protein GSU1996 0.0002
4903 Methyl-accepting chemotaxis protein Tar4 0.0002
4999 Cytochrome P450 165B3 CYP165B3 0.0002
4960 Putative cytochrome P450-family protein SCO7417 0.0002
4931 Cytochrome P450 167A1 CYP167A1 0.0002
4926 Heme-based aerotactic transducer hemAT hemAT 0.0002
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0002
4993 Hydroxylamine oxidoreductase hao1 0.0002
4972 P450cin cinA 0.0002
3093 Catalase HPII katE 0.0002
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0002
4952 Catalase/peroxidase katA 0.0002
4920 Peroxidase/catalase katG 0.0001
2119 Cytochrome b5 CYB5A 0.0001
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0001
4990 PpcA ppcA 0.0001
4988 Sulfite oxidase, mitochondrial SUOX 0.0001
3375 Acidic cytochrome c3 Not Available 0.0001
2915 Sensor protein fixL fixL 0.0001
4944 Sensor protein fixL fixL 0.0001
4037 Hypothetical protein GPX1 0.0001
4297 Hypothetical protein SP_1951 0.0001
4521 Hypothetical protein BC_2969 0.0001
4540 Hypothetical protein TM_1070 0.0001
4555 Hypothetical protein MT1739 0.0001
4569 Hypothetical protein mshD 0.0001
4578 Hypothetical protein PA3270 0.0001
4747 Hypothetical protein PA3967 0.0001
5177 Hypothetical protein TM_0096 0.0001
5194 Hypothetical protein PA1204 0.0001
5240 Hypothetical protein Rv2991 0.0001
5370 Hypothetical protein TM_1158 0.0001
5710 Hypothetical protein Tb927.5.1360 0.0001
3570 Cytochrome P450 152A1 cypC 0.0001
4385 Cytochrome c' Not Available 0.0001
4967 Cytochrome c' cycA 0.0001
5038 Cytochrome c' Not Available 0.0001
5223 Cytochrome c' cycP 0.0001
4813 Heme oxygenase hmuO 0.0001
5769 Heme oxygenase Not Available 0.0001
4992 Cytochrome c peroxidase Not Available 0.0001
4289 Cytochrome P450 TT_P0059 0.0001
6262 Cytochrome P450 staP 0.0001
2230 Catalase CAT 0.0001
3249 Catalase katA 0.0001
3625 Catalase katA 0.0001
4539 Catalase katA 0.0001
4941 Catalase katB 0.0001
3670 Soluble cytochrome b562 precursor cybC 0.0001
3411 Cytochrome P450 121 cyp121 0.0001
3291 Cytochrome c-552 cycA 0.0001
4927 Cytochrome c-552 nrfA 0.0001
4938 Cytochrome c-552 cycA 0.0001
4953 Cytochrome c-552 nrfA 0.0001
5217 Cytochrome c-552 cycM 0.0001
2617 Nitric oxide synthase oxygenase nos 0.0001
2701 Nitric oxide synthase oxygenase nos 0.0001
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0001
2972 6-deoxyerythronolide B hydroxylase eryF 0.0001
4608 Putative cytochrome P450 SCO1207 0.0001
4963 Putative cytochrome P450 SCO2884 0.0001
6254 Putative cytochrome P450 SCO6998 0.0001
358 Cystathionine beta-synthase CBS 0.0001
693 Hemoglobin subunit beta HBB 0.0001
6268 Hydroxyacid oxidase 1 HAO1 0.0001
810 Heme oxygenase 1 HMOX1 0.0001
3391 Heme oxygenase 1 pbsA1 0.0001
2298 Cytochrome P450-cam camC 0.0001
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