DT-Web

DB01892 - Hyperforin


Identification
Name Hyperforin
Accession Number DB01892 (EXPT01804)
Type small molecule
Description Hyperforin is a phytochemical produced by some of the members of the plant genus Hypericum, notably Hypericum perforatum (St John's wort).
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 536.785
Groups nutraceutical
Monoisotopic Weight 536.386560152
Pharmacology
Indication Not Available
Mechanism of action Hyperforin is believed to be the primary active constituent responsible for the antidepressant and anxiolytic properties of the extracts of St. John's wort. It acts as a reuptake inhibitor of monoamines, including serotonin, norepinephrine, dopamine, and of GABA and glutamate, with IC50 values of 0.05-0.10 mcg/ml for all compounds, with the exception of glutamate, which is in the 0.5 mcg/ml range. It appears to exert these effects by activating the transient receptor potential ion channel TRPC6. Activation of TRPC6 induces the entry of sodium and calcium into the cell which causes inhibition of monoamine reuptake.
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Oral LD50 (rat):5628 mg/kg; Skin LD50 (rabbit): 15800 mg/kg; Subcutaneous LD50 (mouse):9800 mg/kg; Intraperitoneal LD50 (rabbit):1826 mg/kg
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Prostaglandin G/H synthase 1
Name Prostaglandin G/H synthase 1
Gene Name PTGS1
Pharmacological action unknown
Actions inhibitor
References
  • Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. - Pubmed
DTHybrid score 0.4854
Nuclear receptor subfamily 1 group I member 2
Name Nuclear receptor subfamily 1 group I member 2
Gene Name NR1I2
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.3419
Arachidonate 5-lipoxygenase
Name Arachidonate 5-lipoxygenase
Gene Name ALOX5
Pharmacological action unknown
Actions inhibitor
References
  • Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. - Pubmed
DTHybrid score 0.3123

Transporters


Canalicular multispecific organic anion transporter 1
Name Canalicular multispecific organic anion transporter 1
Gene Name ABCC2
Actions inducer
References
  • Kast HR, Goodwin B, Tarr PT, Jones SA, Anisfeld AM, Stoltz CM, Tontonoz P, Kliewer S, Willson TM, Edwards PA: Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor. J Biol Chem. 2002 Jan 25;277(4):2908-15. Epub 2001 Nov 12. - Pubmed
DTHybrid score 0.2252
Solute carrier organic anion transporter family member 1B1
Name Solute carrier organic anion transporter family member 1B1
Gene Name SLCO1B1
Actions inhibitor
References
  • Tirona RG, Leake BF, Wolkoff AW, Kim RB: Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation. J Pharmacol Exp Ther. 2003 Jan;304(1):223-8. - Pubmed
DTHybrid score 0.2339

Predictions


Id Partner name Gene Name Score
290 Prostaglandin G/H synthase 2 PTGS2 0.1923
4512 Cytochrome P450 3A4 CYP3A4 0.1374
4757 Cytochrome P450 2C9 CYP2C9 0.1239
1588 Multidrug resistance protein 1 ABCB1 0.113
4924 Cytochrome P450 2C8 CYP2C8 0.1056
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.1026
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0826
4200 Cytochrome P450 1A2 CYP1A2 0.0768
6016 Cytochrome P450 2C19 CYP2C19 0.0722
1729 Solute carrier family 22 member 6 SLC22A6 0.0714
4118 Cytochrome P450 3A5 CYP3A5 0.0649
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0623
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0607
587 Serum albumin ALB 0.0596
284 DNA-directed RNA polymerase beta chain rpoB 0.0517
5773 DNA-directed RNA polymerase beta chain rpoB 0.0517
862 Multidrug resistance-associated protein 1 ABCC1 0.0506
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0495
776 Bile salt export pump ABCB11 0.0487
6182 Cytochrome P450 2J2 CYP2J2 0.0472
6030 Cytochrome P450 2B6 CYP2B6 0.0453
1757 Myeloperoxidase MPO 0.0439
6142 Solute carrier family 22 member 8 SLC22A8 0.0439
6107 Cytochrome P450 3A7 CYP3A7 0.0438
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0429
4119 Cytochrome P450 2D6 CYP2D6 0.0427
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0416
2164 Multidrug resistance-associated protein 4 ABCC4 0.0414
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0409
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0403
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0367
703 NADPH azoreductase azr 0.0352
6141 Sodium/bile acid cotransporter SLC10A1 0.0323
70 Type-1 angiotensin II receptor AGTR1 0.0323
6024 Cytochrome P450 1A1 CYP1A1 0.031
1024 Solute carrier family 22 member 11 SLC22A11 0.0307
61 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0304
2644 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0304
2710 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0304
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0304
3923 Cholinesterase BCHE 0.0279
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0276
6013 Cytochrome P450 2E1 CYP2E1 0.026
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0253
6148 Multidrug resistance-associated protein 7 ABCC10 0.0248
5718 Cytochrome P450 2A6 CYP2A6 0.0247
2907 Oxysterols receptor LXR-beta NR1H2 0.0242
6283 Oxysterols receptor LXR-alpha NR1H3 0.0242
6143 Solute carrier family 22 member 7 SLC22A7 0.0241
1898 Cytochrome P450 1B1 CYP1B1 0.0239
6145 Solute carrier family 22 member 1 SLC22A1 0.0237
136 Estrogen receptor ESR1 0.0236
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0235
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0218
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0202
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0202
118 Organic cation/carnitine transporter 2 SLC22A5 0.0197
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0196
1507 Cytochrome c CYCS 0.0195
78 Acetyl-CoA acetyltransferase, mitochondrial ACAT1 0.0189
6144 Solute carrier family 22 member 2 SLC22A2 0.0176
88 Retinoic acid receptor RXR-beta RXRB 0.0176
6228 Nuclear receptor coactivator 1 NCOA1 0.0173
6241 Nuclear receptor coactivator 2 NCOA2 0.0171
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.017
4077 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform PPP2CB 0.0163
86 SEC14-like protein 4 SEC14L4 0.0163
375 SEC14-like protein 3 SEC14L3 0.0162
4076 Diacylglycerol kinase alpha DGKA 0.0162
33 Cystine/glutamate transporter SLC7A11 0.0162
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0162
1650 Heme carrier protein 1 SLC46A1 0.0159
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0154
13 Aminomethyltransferase, mitochondrial AMT 0.0154
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0152
708 Alpha-tocopherol transfer protein TTPA 0.0148
904 Glutathione S-transferase P GSTP1 0.0145
283 SEC14-like protein 2 SEC14L2 0.0145
738 Monocarboxylate transporter 1 SLC16A1 0.0142
899 Glutathione S-transferase Mu 3 GSTM3 0.0142
905 Glutathione transferase omega-1 GSTO1 0.0142
4078 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform PPP2CA 0.0138
3587 Gastrotropin FABP6 0.0137
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0137
997 Protein kinase C beta type PRKCB 0.0136
850 Vasopressin V1b receptor AVPR1B 0.0134
373 Transthyretin TTR 0.0133
1970 Protein kinase C alpha type PRKCA 0.0125
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0125
6106 Cytochrome P450 2C18 CYP2C18 0.0125
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0124
186 Glutamate--cysteine ligase catalytic subunit GCLC 0.0122
810 Heme oxygenase 1 HMOX1 0.0121
3391 Heme oxygenase 1 pbsA1 0.0121
185 Vasopressin V1a receptor AVPR1A 0.0118
29 Tubulin beta-1 chain TUBB1 0.0118
817 DNA topoisomerase 2-alpha TOP2A 0.0117
322 Vasopressin V2 receptor AVPR2 0.0115
6136 Multidrug resistance-associated protein 5 ABCC5 0.0115
477 DNA topoisomerase 4 subunit A parC 0.0113
886 DNA topoisomerase 4 subunit A parC 0.0113
6226 DNA topoisomerase 4 subunit A parC 0.0113
404 DNA gyrase subunit A gyrA 0.0111
6224 DNA gyrase subunit A gyrA 0.0111
731 HIV-1 protease HIV-1 protease 0.0109
3932 Glutathione S-transferase A2 GSTA2 0.0109
6085 Fatty acid-binding protein, intestinal FABP2 0.0108
2443 Azurin azu 0.0108
833 Organic cation/carnitine transporter 1 SLC22A4 0.0107
6137 Multidrug resistance-associated protein 6 ABCC6 0.0105
5923 Microtubule-associated protein tau MAPT 0.0103
5924 Microtubule-associated protein 4 MAP4 0.0103
4604 Liver carboxylesterase 1 CES1 0.0101
3811 Cytochrome P450 19A1 CYP19A1 0.01
1654 Interleukin-1 beta IL1B 0.01
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.01
273 Apoptosis regulator Bcl-2 BCL2 0.0099
758 Thyroid hormone receptor alpha THRA 0.0098
1852 Microtubule-associated protein 2 MAP2 0.0096
468 Cytochrome P450 4A11 CYP4A11 0.0096
183 Vascular endothelial growth factor A VEGFA 0.0092
6147 Solute carrier family 22 member 3 SLC22A3 0.0091
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0089
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0087
346 Thyroid hormone receptor beta-1 THRB 0.0087
844 Epidermal growth factor receptor EGFR 0.0086
3312 Fatty acid-binding protein, brain FABP7 0.0086
26 Vascular endothelial growth factor receptor 3 FLT4 0.0085
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0085
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.0084
80 Peroxisome proliferator-activated receptor alpha PPARA 0.0084
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0084
1435 Synaptic vesicle glycoprotein 2A SV2A 0.0084
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0083
494 Caspase-1 CASP1 0.0083
32 Vascular endothelial growth factor receptor 1 FLT1 0.0081
5880 Thrombopoietin receptor MPL 0.0081
6167 Organic solute transporter subunit beta OSTB 0.0081
6166 Organic solute transporter subunit alpha OSTA 0.0081
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.008
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0077
22 30S ribosomal protein S4 rpsD 0.0076
6714 30S ribosomal protein S4 rpsD 0.0076
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0075
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0075
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0073
140 30S ribosomal protein S9 rpsI 0.0072
6719 30S ribosomal protein S9 rpsI 0.0072
6725 30S ribosomal protein S9 rpsI 0.0072
2417 Chloramphenicol acetyltransferase cat 0.0071
3278 Chloramphenicol acetyltransferase cat 0.0071
908 Glutathione S-transferase theta-1 GSTT1 0.007
2077 Caspase-3 CASP3 0.0069
65 Matrix metalloproteinase-9 Not Available 0.0068
407 Vascular endothelial growth factor receptor 2 KDR 0.0066
1629 Transcription factor AP-1 JUN 0.0065
3947 Xanthine dehydrogenase/oxidase XDH 0.0064
614 Progesterone receptor PGR 0.0064
890 Niemann-Pick C1-like protein 1 NPC1L1 0.0063
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0063
594 Thyroxine-binding globulin SERPINA7 0.0063
6031 Cytochrome P450 3A43 CYP3A43 0.0063
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0063
24 Thymidylate synthase TMP1 0.0063
359 Thymidylate synthase TYMS 0.0063
2626 Thymidylate synthase thyA 0.0063
2729 Thymidylate synthase thyA 0.0063
5352 Thymidylate synthase THYA 0.0063
3270 Elongation factor G fusA 0.0062
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0062
2808 Chloramphenicol acetyltransferase 3 cat3 0.0061
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0059
6146 High affinity copper uptake protein 1 SLC31A1 0.0058
7 Nitric oxide synthase, inducible NOS2 0.0057
1760 Aminopeptidase N ANPEP 0.0057
6843 Aminopeptidase N pepN 0.0057
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0056
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0055
117 Sterol O-acyltransferase 1 SOAT1 0.0055
2539 Tubulin alpha-1 chain TUBA4A 0.0055
558 Solute carrier family 12 member 1 SLC12A1 0.0054
228 Beta platelet-derived growth factor receptor PDGFRB 0.0054
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0053
6149 Solute carrier family 22 member 10 SLC22A10 0.0052
2981 Phospholipase A2, membrane associated PLA2G2A 0.0052
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0052
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0052
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0052
504 Mast/stem cell growth factor receptor KIT 0.005
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0049
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.0049
511 5-hydroxytryptamine 1F receptor HTR1F 0.0048
5626 Nucleoside diphosphate kinase B NME2 0.0048
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0047
777 Tumor necrosis factor TNF 0.0047
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0047
869 Estrogen receptor beta ESR2 0.0047
146 Androgen receptor AR 0.0047
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0046
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0046
6163 Copper-transporting ATPase 2 ATP7B 0.0046
6165 Copper-transporting ATPase 1 ATP7A 0.0046
6012 Tryptophan 2,3-dioxygenase TDO2 0.0045
1630 Integrin beta-2 ITGB2 0.0044
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0044
6102 Arylamine N-acetyltransferase 2 NAT2 0.0044
756 Sex hormone-binding globulin SHBG 0.0044
1714 Mitogen-activated protein kinase 3 MAPK3 0.0043
489 Monocarboxylate transporter 2 SLC16A7 0.0043
6043 Putative G-protein coupled receptor 44 GPR44 0.0042
896 Glutathione S-transferase Mu 1 GSTM1 0.0042
6500 Phospholipase A2 PLA2G1B 0.0042
492 Histamine H1 receptor HRH1 0.0041
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0041
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0041
811 Translocator protein TSPO 0.004
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0039
5294 Nucleoside diphosphate kinase A NME1 0.0039
4132 Chloride channel protein ClC-Ka CLCNKA 0.0039
563 Thyroid peroxidase TPO 0.0038
4192 DNA topoisomerase 2-beta TOP2B 0.0038
102 DNA topoisomerase I, mitochondrial TOP1MT 0.0038
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.0038
2232 Interleukin-5 IL5 0.0037
1593 Mucin-2 MUC2 0.0037
2853 14 kDa fatty acid-binding protein Not Available 0.0037
320 5-hydroxytryptamine 1A receptor HTR1A 0.0037
6168 Solute carrier family 22 member 16 SLC22A16 0.0036
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0036
6044 Serum paraoxonase/lactonase 3 PON3 0.0036
199 Monocarboxylate transporter 8 SLC16A2 0.0036
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0035
461 Glycine receptor subunit alpha-3 GLRA3 0.0035
4148 Serine/threonine-protein kinase mTOR MTOR 0.0035
725 5-hydroxytryptamine 1D receptor HTR1D 0.0035
1648 Elastin ELN 0.0035
885 5-hydroxytryptamine 1B receptor HTR1B 0.0034
161 Tubulin beta chain TUBB 0.0034
312 Tubulin beta chain TUB2 0.0034
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0034
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0034
572 Integrin alpha-L ITGAL 0.0033
1525 Heparin-binding growth factor 2 FGF2 0.0033
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0033
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0033
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0033
4784 Beta-mannosidase manB 0.0032
6695 Beta-mannosidase BT_0458 0.0032
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0032
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0032
1353 DNA topoisomerase 1 TOP1 0.0032
3552 DNA topoisomerase 1 topA 0.0032
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0031
1123 Eosinophil cationic protein RNASE3 0.0031
131 Synaptic vesicular amine transporter SLC18A2 0.0031
4122 Histone deacetylase 2 HDAC2 0.003
260 Cytochrome P450 51 ERG11 0.003
761 Cytochrome P450 51 ERG11 0.003
3163 Cytochrome P450 51 cyp51 0.003
737 Mineralocorticoid receptor NR3C2 0.003
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.003
636 Mitochondrial carnitine/acylcarnitine carrier protein SLC25A20 0.0029
109 Mitochondrial carnitine/acylcarnitine carrier protein CACL SLC25A29 0.0029
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.0029
165 FL cytokine receptor FLT3 0.0029
3809 Estrogen-related receptor gamma ESRRG 0.0029
768 FK506-binding protein 1A FKBP1A 0.0029
476 RAC-alpha serine/threonine-protein kinase AKT1 0.0028
6103 Arylamine N-acetyltransferase 1 NAT1 0.0028
130 Prostacyclin synthase PTGIS 0.0028
2998 Sialic acid-binding Ig-like lectin 7 SIGLEC7 0.0028
751 Potassium channel subfamily K member 6 KCNK6 0.0028
3917 Methylenetetrahydrofolate reductase MTHFR 0.0027
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0027
1569 G1/S-specific cyclin-D1 CCND1 0.0027
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0027
2183 Fatty acid-binding protein, adipocyte FABP4 0.0026
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0026
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0026
6151 Monocarboxylate transporter 10 SLC16A10 0.0026
412 Peroxisomal carnitine O-octanoyltransferase CROT 0.0026
427 Substance-P receptor TACR1 0.0025
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.0025
551 Carnitine O-acetyltransferase CRAT 0.0025
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.0025
172 Potassium channel subfamily K member 1 KCNK1 0.0025
5818 Folate receptor alpha FOLR1 0.0025
6220 Aryl hydrocarbon receptor AHR 0.0025
4787 Envelope glycoprotein gp160 env 0.0025
4820 Envelope glycoprotein gp160 env 0.0025
5727 Envelope glycoprotein gp160 env 0.0025
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0025
3856 Fibroblast growth factor receptor 3 FGFR3 0.0025
2391 Ferrochelatase hemH 0.0024
6502 Ferrochelatase DKFZp686P18130 0.0024
1591 Ferrochelatase, mitochondrial FECH 0.0024
759 Free fatty acid receptor 1 FFAR1 0.0024
1818 Long-chain-fatty-acid--CoA ligase 3 ACSL3 0.0024
106 Cannabinoid receptor 2 CNR2 0.0024
6211 Tubulin epsilon chain TUBE1 0.0024
6210 Tubulin delta chain TUBD1 0.0024
6212 Tubulin gamma-1 chain TUBG1 0.0024
6033 High affinity interleukin-8 receptor A CXCR1 0.0024
2297 Genome polyprotein Not Available 0.0024
2322 Genome polyprotein Not Available 0.0024
2694 Genome polyprotein Not Available 0.0024
2719 Genome polyprotein Not Available 0.0024
2860 Genome polyprotein Not Available 0.0024
2928 Genome polyprotein Not Available 0.0024
3160 Genome polyprotein Not Available 0.0024
3260 Genome polyprotein Not Available 0.0024
4783 Genome polyprotein Not Available 0.0024
5726 Genome polyprotein Not Available 0.0024
5779 Genome polyprotein Not Available 0.0024
5867 Genome polyprotein Not Available 0.0024
6253 Genome polyprotein Not Available 0.0024
6301 Genome polyprotein Not Available 0.0024
6380 Genome polyprotein Not Available 0.0024
6381 Genome polyprotein Not Available 0.0024
6437 Genome polyprotein Not Available 0.0024
6520 Genome polyprotein Not Available 0.0024
6521 Genome polyprotein Not Available 0.0024
6652 Genome polyprotein Not Available 0.0024
6734 Genome polyprotein Not Available 0.0024
6735 Genome polyprotein Not Available 0.0024
6736 Genome polyprotein Not Available 0.0024
6737 Genome polyprotein Not Available 0.0024
6738 Genome polyprotein Not Available 0.0024
6739 Genome polyprotein Not Available 0.0024
6744 Genome polyprotein Not Available 0.0024
6748 Genome polyprotein Not Available 0.0024
6894 Genome polyprotein Not Available 0.0024
6898 Genome polyprotein Not Available 0.0024
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0024
3941 Amine oxidase [flavin-containing] A MAOA 0.0024
68 Cannabinoid receptor 1 CNR1 0.0023
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0023
723 Cytosolic phospholipase A2 PLA2G4A 0.0023
1192 Sulfotransferase 1A1 SULT1A1 0.0022
293 Gamma-glutamyl hydrolase GGH 0.0022
3480 Mannan endo-1,4-beta-mannosidase manA 0.0022
634 Squalene monooxygenase SQLE 0.0022
7196 Squalene monooxygenase ERG1 0.0022
4943 Cytochrome c6 petJ 0.0022
4934 Cytochrome c-551 nirM 0.0022
5218 Cytochrome c-551 nirM 0.0022
4905 Cytochrome c2 Not Available 0.0022
4939 Cytochrome c2 cycA 0.0022
4964 Cytochrome c2 cycA 0.0022
4979 Cytochrome c2 cycA 0.0022
6673 Cytochrome c2 cycA 0.0022
4947 Bacterial hemoglobin vhb 0.0022
4916 Cyanoglobin glbN 0.0022
4994 Hemoglobin-like protein HbO glbO 0.0022
4975 Cytochrome c-556 RPA3973 0.0022
4942 Diheme cytochrome c napB napB 0.0022
4909 CooA protein cooA 0.0022
4954 Soluble cytochrome b558 Not Available 0.0022
3116 Bacterioferritin bfr 0.0022
4906 Bacterioferritin bfr 0.0022
4965 Bacterioferritin bfr 0.0022
4981 Iron-starvation protein PigA pigA 0.0022
4915 Cytochrome c-550 psbV 0.0022
4959 Cytochrome c-550 psbV 0.0022
5216 Cytochrome c-550 psbV 0.0022
4925 Cytochrome c-type protein SHP shp 0.0022
4907 Cytochrome c-L moxG 0.0022
6865 Cytochrome c-L moxG 0.0022
4936 Cytochrome c2 iso-2 Not Available 0.0022
4989 Cytochrome c551 peroxidase ccp 0.0022
5222 Cytochrome c551 peroxidase ccpA 0.0022
4998 Hemoglobin-like protein yjbI yjbI 0.0022
4984 Neuroglobin NGB 0.0022
5000 HemO hemO 0.0022
644 Heme oxygenase 2 HMOX2 0.0022
4982 Heme oxygenase 2 pbsA2 0.0022
4935 Cytochrome c-554 cycA1 0.0022
4999 Cytochrome P450 165B3 CYP165B3 0.0022
4764 Cytochrome P450 165C4 CYP165C4 0.0022
4961 Hemophore HasA hasA 0.0022
4976 Apocytochrome f petA 0.0022
6407 Apocytochrome f petA 0.0022
4937 Cytochrome oxidase subunit II rcoxA 0.0022
4971 Nonaheme cytochrome c hmcA 0.0022
4910 Cytoglobin CYGB 0.0022
4904 Cytochrome c family protein GSU1996 0.0022
4926 Heme-based aerotactic transducer hemAT hemAT 0.0022
4931 Cytochrome P450 167A1 CYP167A1 0.0022
4972 P450cin cinA 0.0022
4960 Putative cytochrome P450-family protein SCO7417 0.0022
4903 Methyl-accepting chemotaxis protein Tar4 0.0022
4952 Catalase/peroxidase katA 0.0022
4922 Cytochrome c, putative SO_4144 0.0022
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0022
4993 Hydroxylamine oxidoreductase hao1 0.0022
3093 Catalase HPII katE 0.0022
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0022
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0021
3437 Eosinophil lysophospholipase CLC 0.0021
1313 Lactoylglutathione lyase GLO1 0.0021
6495 Cytochrome c oxidase subunit 7C, mitochondrial COX7C 0.0021
6499 Cytochrome c oxidase polypeptide 7A1, mitochondrial COX7A1 0.0021
6496 Cytochrome c oxidase subunit 8A, mitochondrial COX8A 0.0021
6493 Cytochrome c oxidase subunit 6C COX6C 0.0021
6498 Cytochrome c oxidase subunit 6B1 COX6B1 0.0021
6497 Cytochrome c oxidase subunit 6A2, mitochondrial COX6A2 0.0021
6494 Cytochrome c oxidase subunit 7B, mitochondrial COX7B 0.0021
6491 Cytochrome c oxidase subunit 5A, mitochondrial COX5A 0.0021
6489 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial COX4I1 0.0021
5793 Cytochrome c oxidase subunit 2 MT-CO2 0.0021
6559 Cytochrome c oxidase subunit 2 ctaC 0.0021
6669 Cytochrome c oxidase subunit 2 ctaC 0.0021
6490 Cytochrome c oxidase subunit 3 MT-CO3 0.0021
371 Cytochrome c oxidase subunit 1 MT-CO1 0.0021
6558 Cytochrome c oxidase subunit 1 ctaD 0.0021
1053 BC269730_2 FADS1 0.0021
1395 Sodium/calcium exchanger 1 SLC8A1 0.0021
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0021
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0021
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0021
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0021
6042 Prostaglandin reductase 2 PTGR2 0.0021
823 Fibroblast growth factor receptor 2 FGFR2 0.002
4120 NADPH--cytochrome P450 reductase POR 0.002
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.002
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.002
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.002
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.002
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.002
1558 Transient receptor potential cation channel subfamily V member 1 TRPV1 0.002
132 ATP-binding cassette sub-family A member 1 ABCA1 0.002
6014 Cytochrome P450 2A13 CYP2A13 0.002
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0019
2540 Choloylglycine hydrolase cbh 0.0019
6836 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial HIBCH 0.0019
6837 Serine/threonine-protein kinase 17B STK17B 0.0019
3601 Dihydropteroate synthase 1 folP1 0.0019
3807 Dihydropteroate synthase 1 folP1 0.0019
3808 Dihydropteroate synthase 2 folP2 0.0019
952 Dipeptidyl peptidase 4 DPP4 0.0019
6131 Carbonic anhydrase 14 CA14 0.0019
891 Dihydropteroate synthase folP 0.0018
5359 Dihydropteroate synthase folP 0.0018
7175 Dihydropteroate synthase sulI 0.0018
2236 Casein kinase II subunit alpha CSNK2A1 0.0018
342 P protein [Includes: DNA-directed DNA polymerase P 0.0018
612 P protein [Includes: DNA-directed DNA polymerase P 0.0018
3920 Methylenetetrahydrofolate reductase intermediate form MTHFR 0.0018
6501 Fatty acid-binding protein, liver FABP1 0.0018
3763 5,10-methylenetetrahydrofolate reductase metF 0.0018
3918 5,10-methylenetetrahydrofolate reductase MTHFR 0.0018
5094 5,10-methylenetetrahydrofolate reductase metF 0.0018
59 AMT protein AMT 0.0018
3919 Methionyl-tRNA formyltransferase, mitochondrial MTFMT 0.0018
1202 10-formyltetrahydrofolate dehydrogenase ALDH1L1 0.0018
3810 Catechol O-methyltransferase COMT 0.0018
459 Retinoic acid receptor RXR-alpha RXRA 0.0018
677 Choline-phosphate cytidylyltransferase A PCYT1A 0.0018
1176 Mitogen-activated protein kinase 1 MAPK1 0.0018
467 Delta-type opioid receptor OPRD1 0.0018
76 Nitric-oxide synthase, brain NOS1 0.0017
696 Kappa-type opioid receptor OPRK1 0.0017
267 Plasminogen activator inhibitor 1 SERPINE1 0.0017
2449 Tubulin alpha-3 chain TUBA1A 0.0017
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0017
760 Fibroblast growth factor 1 FGF1 0.0017
2207 Rhodopsin RHO 0.0017
847 Mu-type opioid receptor OPRM1 0.0017
6656 UDP-glucuronosyltransferase 3A1 UGT3A1 0.0017
6221 Steroid hormone receptor ERR1 ESRRA 0.0016
4920 Peroxidase/catalase katG 0.0016
4103 Proteasome subunit beta type 2 PSMB2 0.0016
4102 Proteasome subunit beta type 5 PSMB5 0.0016
4101 Proteasome subunit beta type 1 PSMB1 0.0016
702 UMP-CMP kinase CMPK1 0.0016
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0016
2119 Cytochrome b5 CYB5A 0.0016
4948 Cytochrome c-553 Not Available 0.0016
4990 PpcA ppcA 0.0016
4923 Cytochrome c3 DvMF_2499 0.0016
4945 Cytochrome c3 Not Available 0.0016
4949 Cytochrome c3 DVU_3171 0.0016
4968 Cytochrome c3 cytc3 0.0016
4997 Cytochrome c3 SO_2727 0.0016
5219 Cytochrome c3 cyd 0.0016
4902 Nine-heme cytochrome c Ddes_2038 0.0016
3189 High-molecular-weight cytochrome c hmcA 0.0016
4289 Cytochrome P450 TT_P0059 0.0016
6262 Cytochrome P450 staP 0.0016
3570 Cytochrome P450 152A1 cypC 0.0016
4992 Cytochrome c peroxidase Not Available 0.0016
4988 Sulfite oxidase, mitochondrial SUOX 0.0016
2915 Sensor protein fixL fixL 0.0016
4944 Sensor protein fixL fixL 0.0016
4385 Cytochrome c' Not Available 0.0016
4967 Cytochrome c' cycA 0.0016
5038 Cytochrome c' Not Available 0.0016
5223 Cytochrome c' cycP 0.0016
3375 Acidic cytochrome c3 Not Available 0.0016
4813 Heme oxygenase hmuO 0.0016
5769 Heme oxygenase Not Available 0.0016
822 Aldose reductase AKR1B1 0.0016
2230 Catalase CAT 0.0015
3249 Catalase katA 0.0015
3625 Catalase katA 0.0015
4539 Catalase katA 0.0015
4941 Catalase katB 0.0015
296 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial MTHFD2 0.0015
6599 HTH-type transcriptional regulator ttgR ttgR 0.0015
1374 Natriuretic peptides B NPPB 0.0015
1827 Gap junction alpha-1 protein GJA1 0.0015
1908 Vascular cell adhesion protein 1 VCAM1 0.0015
824 Sodium-dependent serotonin transporter SLC6A4 0.0015
4785 Ig gamma-1 chain C region IGHG1 0.0015
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0015
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0015
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0015
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0015
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0015
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0015
6020 Aldehyde oxidase AOX1 0.0015
6002 Prostaglandin E2 receptor EP4 subtype PTGER4 0.0015
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0015
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0015
2599 Tyrosine-protein kinase HCK HCK 0.0015
357 Carbonic anhydrase 2 CA2 0.0014
921 Glutamate receptor 2 GRIA2 0.0014
3884 SHMT2 protein SHMT2 0.0014
3901 SHMT2 protein SHMT2 0.0014
3885 Hypothetical protein DKFZp686P09201 DKFZp686P09201 0.0014
3879 Serine hydroxymethyltransferase 2 Not Available 0.0014
321 Serine hydroxymethyltransferase, mitochondrial SHMT2 0.0014
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0014
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0014
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.0014
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0014
4131 Prostaglandin E2 receptor, EP3 subtype PTGER3 0.0014
406 Prostaglandin E2 receptor, EP2 subtype PTGER2 0.0014
3670 Soluble cytochrome b562 precursor cybC 0.0014
3411 Cytochrome P450 121 cyp121 0.0014
528 5-hydroxytryptamine 1E receptor HTR1E 0.0014
6344 ATP synthase subunit gamma, mitochondrial ATP5C1 0.0014
6343 ATP synthase subunit beta, mitochondrial ATP5B 0.0014
6342 ATP synthase subunit alpha, mitochondrial ATP5A1 0.0014
365 Dihydrofolate reductase DHFR 0.0014
2381 Dihydrofolate reductase DFR1 0.0014
2833 Dihydrofolate reductase Not Available 0.0014
2931 Dihydrofolate reductase folA 0.0014
3544 Dihydrofolate reductase folA 0.0014
3682 Dihydrofolate reductase folA 0.0014
6642 Dihydrofolate reductase folA 0.0014
6756 Dihydrofolate reductase dfrA 0.0014
2617 Nitric oxide synthase oxygenase nos 0.0014
2701 Nitric oxide synthase oxygenase nos 0.0014
914 Formimidoyltransferase-cyclodeaminase FTCD 0.0014
3291 Cytochrome c-552 cycA 0.0014
4927 Cytochrome c-552 nrfA 0.0014
4938 Cytochrome c-552 cycA 0.0014
4953 Cytochrome c-552 nrfA 0.0014
5217 Cytochrome c-552 cycM 0.0014
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0014
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0014
4386 Hemoglobin-like protein HbN glbN 0.0014
3102 Flavohemoprotein hmp 0.0014
4969 Flavohemoprotein hmp 0.0014
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0013
518 Peroxidase/catalase T katG 0.0013
831 D(2) dopamine receptor DRD2 0.0013
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0013
291 Nitric-oxide synthase, endothelial NOS3 0.0013
517 Alcohol dehydrogenase 1C ADH1C 0.0013
809 Methionine synthase MTR 0.0013
2935 Methionine synthase metH 0.0013
4773 Deoxycytidine kinase DCK 0.0013
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0013
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0013
6218 Pannexin-1 PANX1 0.0013
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0013
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0012
605 Fumarate reductase flavoprotein subunit frdA 0.0012
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0012
3673 Fumarate reductase flavoprotein subunit fccA 0.0012
4912 Fumarate reductase flavoprotein subunit ifcA 0.0012
6549 Fumarate reductase flavoprotein subunit frdA 0.0012
2021 Thrombomodulin THBD 0.0012
367 Serine hydroxymethyltransferase, cytosolic SHMT1 0.0012
3127 Nitrite reductase nirS 0.0012
3284 Nitrite reductase nirS 0.0012
2972 6-deoxyerythronolide B hydroxylase eryF 0.0012
3221 Cytochrome c4 cc4 0.0012
6259 (3R)-hydroxymyristoyl-acyl carrier protein dehydratase fabZ 0.0012
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0012
716 5-hydroxytryptamine 7 receptor HTR7 0.0012
556 Alpha-1A adrenergic receptor ADRA1A 0.0012
4608 Putative cytochrome P450 SCO1207 0.0012
4963 Putative cytochrome P450 SCO2884 0.0012
6254 Putative cytochrome P450 SCO6998 0.0012
2404 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PIK3CG 0.0012
1864 RET proto-oncogene RET 0.0011
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0011
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0011
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0011
1275 Estrogen sulfotransferase SULT1E1 0.0011
358 Cystathionine beta-synthase CBS 0.0011
340 Apoptotic protease-activating factor 1 APAF1 0.0011
436 5-hydroxytryptamine 2B receptor HTR2B 0.0011
84 Nuclear receptor 0B1 NR0B1 0.0011
1050 Bile salt sulfotransferase SULT2A1 0.0011
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0011
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0011
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0011
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0011
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0011
693 Hemoglobin subunit beta HBB 0.001
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.001
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.001
469 Annexin A1 ANXA1 0.001
1039 Histone deacetylase 9 HDAC9 0.001
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.001
6268 Hydroxyacid oxidase 1 HAO1 0.001
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.001
825 Arsenical pump-driving ATPase ASNA1 0.001
3435 Arsenical pump-driving ATPase arsA 0.001
486 Serine/threonine-protein kinase ALS2CR7 CDK15 0.001
510 Serine/threonine-protein kinase receptor R3 ACVRL1 0.001
2105 ATP-binding cassette sub-family G member 1 ABCG1 0.001
745 Anti-Muellerian hormone type-2 receptor AMHR2 0.001
483 A-Raf proto-oncogene serine/threonine-protein kinase ARAF 0.001
733 Activin receptor type 1B ACVR1B 0.001
154 AFG3-like protein 2 AFG3L2 0.001
225 NEDD8-activating enzyme E1 regulatory subunit NAE1 0.001
21 Beta-adrenergic receptor kinase 2 ADRBK2 0.001
377 Beta-adrenergic receptor kinase 1 ADRBK1 0.001
395 ALK tyrosine kinase receptor Not Available 0.001
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.001
1618 High affinity nerve growth factor receptor NTRK1 0.001
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0009
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0009
292 Activin receptor type-1 ACVR1 0.0009
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0009
849 Activated CDC42 kinase 1 TNK2 0.0009
380 Cytochrome P450 17A1 CYP17A1 0.0009
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0009
1792 Tissue-type plasminogen activator PLAT 0.0009
2298 Cytochrome P450-cam camC 0.0009
821 Acetyl-coenzyme A synthetase 2-like, mitochondrial ACSS1 0.0009
704 Long-chain-fatty-acid--CoA ligase 1 ACSL1 0.0009
386 Acetyl-coenzyme A synthetase, cytoplasmic ACSS2 0.0009
297 Adenylate cyclase type 1 ADCY1 0.0009
289 Cytosolic purine 5'-nucleotidase NT5C2 0.0008
465 Calmodulin CALM1 0.0008
1184 Interferon beta IFNB1 0.0008
484 Tyrosine-protein kinase ABL2 ABL2 0.0008
748 5'-AMP-activated protein kinase catalytic subunit alpha-1 PRKAA1 0.0008
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0008
193 Beta-1 adrenergic receptor ADRB1 0.0008
766 Beta-2 adrenergic receptor ADRB2 0.0007
4043 Glutaredoxin-2, mitochondrial GLRX2 0.0007
4034 Glutaredoxin-1 GLRX 0.0007
910 Epididymal secretory glutathione peroxidase GPX5 0.0007
903 Glutathione S-transferase A5 GSTA5 0.0007
4037 Hypothetical protein GPX1 0.0007
4297 Hypothetical protein SP_1951 0.0007
4521 Hypothetical protein BC_2969 0.0007
4540 Hypothetical protein TM_1070 0.0007
4555 Hypothetical protein MT1739 0.0007
4569 Hypothetical protein mshD 0.0007
4578 Hypothetical protein PA3270 0.0007
4747 Hypothetical protein PA3967 0.0007
5177 Hypothetical protein TM_0096 0.0007
5194 Hypothetical protein PA1204 0.0007
5240 Hypothetical protein Rv2991 0.0007
5370 Hypothetical protein TM_1158 0.0007
5710 Hypothetical protein Tb927.5.1360 0.0007
1928 Leukotriene C4 synthase LTC4S 0.0007
4029 Microsomal glutathione S-transferase 3 MGST3 0.0007
4032 Microsomal glutathione S-transferase 1 MGST1 0.0007
4030 Thioredoxin domain-containing protein 12 TXNDC12 0.0007
4040 Glutathione peroxidase 7 GPX7 0.0007
907 Glutathione peroxidase 2 GPX2 0.0007
4038 Glutathione peroxidase 4 GPX4 0.0007
1975 Phospholipid hydroperoxide glutathione peroxidase, mitochondrial GPX4 0.0007
906 Glutathione peroxidase 1 GPX1 0.0007
4039 CDNA FLJ23636 fis, clone CAS07176 GPX8 0.0007
4035 Glutathione S-transferase Mu 5 GSTM5 0.0007
4036 Glutathione peroxidase 6 GPX6 0.0007
900 Glutathione S-transferase A4 GSTA4 0.0007
911 Glutathione peroxidase 3 GPX3 0.0007
4042 Glutathione transferase omega-2 GSTO2 0.0007
4033 S-formylglutathione hydrolase ESD 0.0007
1056 Gamma-glutamyltranspeptidase 1 GGT1 0.0007
740 Argininosuccinate synthase ASS1 0.0007
865 Argininosuccinate synthase ASS1 0.0007
2680 Argininosuccinate synthase argG 0.0007
3194 Argininosuccinate synthase argG 0.0007
6021 Adenosine kinase ADK 0.0007
661 ADP/ATP translocase 1 SLC25A4 0.0007
242 Asparagine synthetase [glutamine-hydrolyzing] ASNS 0.0007
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0007
4666 Fucose-binding lectin PA-IIL lecB 0.0007
789 Alpha-1D adrenergic receptor ADRA1D 0.0007
2372 Bifunctional tail protein 9 0.0007
3319 Hydroxyacylglutathione hydrolase HAGH 0.0007
898 Glutathione S-transferase A3 GSTA3 0.0007
897 Glutathione S-transferase kappa 1 GSTK1 0.0007
909 Maleylacetoacetate isomerase GSTZ1 0.0007
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0006
4878 Glycoprotein hormones alpha chain CGA 0.0006
1052 Cytotoxic T-lymphocyte protein 4 CTLA4 0.0006
1072 Granzyme B GZMB 0.0006
4871 Endo-beta-N-acetylglucosaminidase F3 endOF3 0.0006
4880 Membrane cofactor protein CD46 0.0006
4889 Ig epsilon chain C region IGHE 0.0006
4877 Beta-mannanase man 0.0006
1563 Platelet glycoprotein Ib alpha chain GP1BA 0.0006
4850 Beta-2-glycoprotein 1 APOH 0.0006
4856 CD209 antigen CD209 0.0006
4189 Alpha-galactosidase A GLA 0.0006
4869 Major capsid protein A430L 0.0006
757 Fusion glycoprotein F0 F 0.0006
4875 Fusion glycoprotein F0 F 0.0006
4852 Reticulon-4 receptor RTN4R 0.0006
4845 ADAM 33 ADAM33 0.0006
1354 Beta-glucuronidase GUSB 0.0006
442 Envelope glycoprotein gp41 0.0006
4859 Envelope glycoprotein env 0.0006
4882 Dipeptidyl aminopeptidase-like protein 6 DPP6 0.0006
4721 Beta-1,4-mannanase manA 0.0006
3352 Structural polyprotein Not Available 0.0006
3628 Structural polyprotein Not Available 0.0006
4892 Structural polyprotein Not Available 0.0006
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0006
4041 Microsomal glutathione S-transferase 2 MGST2 0.0006
871 Glucocorticoid receptor NR3C1 0.0006
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0006
2165 Glutathione S-transferase Mu 2 GSTM2 0.0006
207 Glutathione synthetase GSS 0.0006
5269 Glutathione synthetase gshB 0.0006
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0006
4193 Atrial natriuretic peptide clearance receptor NPR3 0.0006
793 T-cell surface antigen CD2 CD2 0.0006
4861 Interleukin-6 receptor alpha chain IL6R 0.0006
119 Carcinoembryonic antigen-related cell adhesion molecule 1 CEACAM1 0.0006
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0006
3837 Cytokine receptor common beta chain CSF2RB 0.0006
502 5-hydroxytryptamine 2A receptor HTR2A 0.0006
901 Glutathione S-transferase Mu 4 GSTM4 0.0005
2430 Chondroitinase B cslB 0.0005
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0005
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0005
4031 Glutathione S-transferase A1 GSTA1 0.0005
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0005
1379 Interleukin-12 subunit beta IL12B 0.0005
4890 Hemagglutinin HA 0.0005
6566 Hemagglutinin Not Available 0.0005
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.0005
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.0005
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0005
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0005
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.0005
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0005
714 Glutathione reductase, mitochondrial GSR 0.0005
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0005
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0005
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0005
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0005
4857 Zinc-alpha-2-glycoprotein AZGP1 0.0005
6858 Inactive carboxylesterase 4 CES1P1 0.0005
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.0005
6120 Cation-independent mannose-6-phosphate receptor IGF2R 0.0005
18 High affinity immunoglobulin epsilon receptor subunit alpha FCER1A 0.0005
554 Low-density lipoprotein receptor LDLR 0.0004
852 Heparin cofactor 2 SERPIND1 0.0004
1859 Prostatic acid phosphatase ACPP 0.0004
595 Fibrinogen alpha chain FGA 0.0004
3140 Hemagglutinin-neuraminidase HN 0.0004
3609 Hemagglutinin-neuraminidase HN 0.0004
3444 Cyanovirin-N Not Available 0.0004
3258 Mannosyl-oligosaccharide alpha-1,2-mannosidase MSDC 0.0004
4509 Acetoin(diacetyl) reductase budC 0.0004
958 Insulin-like growth factor 1 receptor IGF1R 0.0004
3689 Endoglucanase A celA 0.0004
3814 Complement C1r subcomponent C1R 0.0004
3009 Beta-glucanase Not Available 0.0004
5411 Slt-IIvB stxB2e 0.0004
5565 Inorganic polyphosphate/ATP-glucomannokinase ppgmk 0.0004
5563 Galectin-2 LGALS2 0.0004
1875 Pulmonary surfactant-associated protein D SFTPD 0.0004
5569 Endo-1,4-beta glucanase EngF engF 0.0004
5046 Ecotin eco 0.0004
3793 Aspartate ammonia-lyase aspA 0.0004
5554 D-galactose-binding periplasmic protein mglB 0.0004
3741 D-galactose-binding periplasmic protein precursor mglB 0.0004
5568 Endoglucanase C307 celC307 0.0004
5553 Endoglucanase E1 Acel_0614 0.0004
5562 Hexokinase Not Available 0.0004
3744 Endoglucanase SS precursor celS 0.0004
5570 Endoglucanase E-4 celD 0.0004
5559 Neopullulanase nplT 0.0004
4670 Cellulase B celB 0.0004
4668 Laminarinase TM_0024 0.0004
4667 BH0236 protein BH0236 0.0004
4671 Endoglucanase C cenC 0.0004
64 Neuraminidase NA 0.0004
641 Neuraminidase NA 0.0004
2676 Neuraminidase NA 0.0004
3026 Neuraminidase NA 0.0004
3519 Neuraminidase NA 0.0004
6007 Neuraminidase NA 0.0004
2577 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase MAN1B1 0.0004
1243 Cathepsin D CTSD 0.0003
1439 Lactotransferrin LTF 0.0003
309 Antithrombin-III SERPINC1 0.0003
1782 Neutrophil gelatinase-associated lipocalin LCN2 0.0003
5176 YtnJ moxC 0.0003
5416 Coat protein VP1 Not Available 0.0003
2705 Dimethyl sulfoxide reductase dmsA 0.0003
5247 Endo-1,4-beta-xylanase Not Available 0.0003
5248 Endo-1,4-beta-xylanase xlnA 0.0003
5250 Endo-1,4-beta-xylanase xyl 0.0003
4669 Endo-1,4-beta-xylanase A xynA 0.0003
4715 Endo-1,4-beta-xylanase A xlnA 0.0003
5560 Endo-1,4-beta-xylanase A xynA 0.0003
1503 Galectin-7 LGALS7 0.0003
5498 Maltoporin lamB 0.0003
5561 Maltoporin lamB 0.0003
5056 Maltooligosyltrehalose trehalohydrolase, putative treZ 0.0003
3525 ADP-ribose pyrophosphatase, mitochondrial NUDT9 0.0003
4622 Amylase Not Available 0.0003
2728 Glucan 1,4-alpha-maltotetraohydrolase amyP 0.0003
6307 Ig gamma-2 chain C region IGHG2 0.0003
2826 Glucose--fructose oxidoreductase gfo 0.0003
1881 Hexokinase-1 HK1 0.0003
2581 Chondroitinase AC cslA 0.0003
6847 Lactase-phlorizin hydrolase LCT 0.0003
2324 Botulinum neurotoxin type B botB 0.0003
3153 Quinoprotein glucose dehydrogenase-B gdhB 0.0003
3747 Cellulase B precursor celB 0.0003
3547 Enterotoxin type B entB 0.0003
2856 Glucosamine-6-phosphate isomerase GNPDA1 0.0003
2564 Glucan 1,4-alpha-maltohexaosidase Not Available 0.0003
4819 Hydrolase Not Available 0.0003
5249 Hydrolase Not Available 0.0003
5436 Hydrolase Not Available 0.0003
2531 Alpha-amylase amyE 0.0003
2948 Alpha-amylase amy 0.0003
3169 Alpha-amylase Not Available 0.0003
2541 Neopullulanase 1 tvaI 0.0003
4811 Amylosucrase ams 0.0003
3091 Maltodextrin phosphorylase malP 0.0003
2606 Neopullulanase 2 tvaII 0.0003
4692 A/G-specific adenine glycosylase mutY 0.0003
3225 Shiga toxin B-chain stxB 0.0003
3365 Beta-amylase spoII 0.0003
4830 Aldose 1-epimerase galM 0.0003
6614 Lactase-like protein LCTL 0.0003
1675 Glucokinase GCK 0.0003
4662 Glucokinase glk 0.0003
3030 Salivary alpha-amylase AMY1A 0.0003
2293 Cyclomaltodextrin glucanotransferase Not Available 0.0003
2508 Cyclomaltodextrin glucanotransferase cgt 0.0003
2523 Cyclomaltodextrin glucanotransferase cgt 0.0003
3207 Cyclomaltodextrin glucanotransferase amyA 0.0003
4272 POSSIBLE CELLULASE CELA1 celA1 0.0003
2570 Tetanus toxin tetX 0.0002
2448 Exoglucanase/xylanase [Includes: Exoglucanase cex 0.0002
3668 Maltose-binding periplasmic protein precursor malE 0.0002
2802 Endoglucanase G celCCG 0.0002
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0002
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0002
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0002
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0002
2440 Endoglucanase F celCCF 0.0002
2245 Xylose isomerase xylA 0.0002
2253 Xylose isomerase xylA 0.0002
2260 Xylose isomerase xylA 0.0002
2431 Xylose isomerase xylA 0.0002
2252 Endoglucanase 5A cel5A 0.0002
10 Glycogen phosphorylase, liver form PYGL 0.0002
2723 Cholera enterotoxin subunit B ctxB 0.0002
4513 Pancreatic alpha-amylase AMY2A 0.0002
2427 Ferrichrome-iron receptor fhuA 0.0002
1152 Glycogen phosphorylase, muscle form PYGM 0.0002
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