DT-Web

DB00635 - Prednisone


Identification
Name Prednisone
Accession Number DB00635 (APRD00340)
Type small molecule
Description A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver. [PubChem]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 358.4281
Groups approved
Monoisotopic Weight 358.178023942
Pharmacology
Indication For the treatment of drug-induced allergic reactions, perennial or seasonal allergic rhinitis, serum sickness, giant cell arteritis acute rheumatic or nonrheumatic carditis, systemic dermatomyositis, systemic lupus erythematosus, atopic dermatitis, contact dermatitis, exfoliative dermatitis, bullous dermatitis herpetiformis, severe seborrheic dermatitis, severe (Stevens-Johnson syndrome) erythema multiforme, mycosis fungoides, pemphigus, severe psoriasis, acute adrenocortical insufficiency, Addison's disease, secondary adrenocortical insufficiency, congenital adrenal hyperplasia, hypercalcemia associated with neoplasms, nonsuppurative thyroiditis, ulceratice colitis, Crohn's disease, acquired hemolytic anemia, congenital hypoplastic anemia, erythroblastopenia, adult secondary thrombocytopenia, adult idiopathic thrombocytopenia purpura, acute or subacute bursitis, epicondylitis, acute nonspecific tenosynovitis, acute or chronic lymphocytic leukemia, Hodgkin's or non-Hodgkin's lynphomas, Waldenstrom's macroglobulinemia, primary brain tumors (adjunct), nephrotic syndrome, tuberculous meningitis, multiple sclerosis, myasthenia gravis. cerebral edema, chorioretinitis, diffuse posterior choroiditis, aleergic conjunctivitis, Herpes zoster ophthalmicus, anterior segment inflammation, iridocyclitis, iritis, keratitis, optoc neuritis, sympathetic ophthalmia, corneal marginal allergic ulcers, symptomatic sarcoidosis, Loeffler's syndrome not manageable by other means, berylliosis, fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate antituberculous chemotherapy and aspiration pneumonitis.
Mechanism of action Prednisone is a glucocorticoid receptor agonist. It is first metabolized in the liver to its active form, prednisolone. Prednisolone crosses cell membranes and binds with high affinity to specific cytoplasmic receptors. The result includes inhibition of leukocyte infiltration at the site of inflammation, interference in the function of mediators of inflammatory response, suppression of humoral immune responses, and reduction in edema or scar tissue. The antiinflammatory actions of corticosteroids are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes. Prednisone can stimulate secretion of various components of gastric juice. Suppression of the production of corticotropin may lead to suppression of endogenous corticosteroids. Prednisone has slight mineralocorticoid activity, whereby entry of sodium into cells and loss of intracellular potassium is stimulated. This is particularly evident in the kidney, where rapid ion exchange leads to sodium retention and hypertension.
Absorption Readily absorbed from the gastrointestinal tract. Rayos, the delayed-release formulation, has a 4-hour release time. To compare, the delayed-release formulation has a Tmax of 6.0 - 6.5 hours in healthy male subjects, whereas the immediate-release formulation has a Tmax of 2.0 hours. The rate of absorption, Cmax, and exposure is comparable between formulations.
Protein binding Extensively bound to plasma proteins.
Biotransformation Prednisone is completely converted to the active metabolite prednisolone by 11?-hydroxysteroid dehydrogenases. It is then further metabolized mainly in the liver. The exposure of prednisolone is 4-6 fold higher than that of prednisone.
Route of elimination Excreted in the urine as sulfate and glucuronide conjugates.
Toxicity Not Available
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions
Drug Mechanism of interaction
Acenocoumarol The corticosteroid, prednisone, alters the anticoagulant effect, acenocoumarol.
Acetylsalicylic acid The corticosteroid, prednisone, may decrease the effect of the salicylate, acetylsalicylic acid.
Ambenonium The corticosteroid, prednisone, may decrease the effect of the anticholinesterase, ambenonium.
Amobarbital The barbiturate, amobarbital, may decrease the effect of the corticosteroid, prednisone.
Anisindione The corticosteroid, prednisone, alters the anticoagulant effect of anisindione.
Aprobarbital The barbiturate, aprobarbital, may decrease the effect of the corticosteroid, prednisone.
Bismuth Subsalicylate The corticosteroid, prednisone, may decrease the effect of the salicylate, bismuth subsalicylate.
Butabarbital The barbiturate, butabarbital, may decrease the effect of the corticosteroid, prednisone.
Butalbital The barbiturate, butalbital, may decrease the effect of the corticosteroid, prednisone.
Butethal The barbiturate, butethal, may decrease the effect of the corticosteroid, prednisone.
Chlorotrianisene The estrogenic agent, chlorotrianisene, may increase the effect of corticosteroid, prednisone.
Clomifene The estrogenic agent, clomifene, may increase the effect of corticosteroid, prednisone.
Conjugated Estrogens The estrogenic agent may increase the effect of corticosteroid, prednisone.
Dicumarol The corticosteroid, prednisone, alters the anticoagulant effect of dicumarol.
Diethylstilbestrol The estrogenic agent, diethylstilbestrol, may increase the effect of corticosteroid, prednisone.
Dihydroquinidine barbiturate The barbiturate, dihydroquinidine barbiturate, may decrease the effect of the corticosteroid, prednisone.
Edrophonium The corticosteroid, prednisone, may decrease the effect of the anticholinesterase, edrophonium.
Estradiol The estrogenic agent, estradiol, may increase the effect of corticosteroid, prednisone.
Estriol The estrogenic agent, estriol, may increase the effect of corticosteroid, prednisone.
Estrone The estrogenic agent, estrone, may increase the effect of corticosteroid, prednisone.
Estropipate The estrogenic agent, estropipate, may increase the effect of corticosteroid, prednisone.
Ethinyl Estradiol The estrogenic agent, ethinyl estradiol, may increase the effect of corticosteroid, prednisone.
Ethotoin The enzyme inducer, ethotoin, may decrease the effect of the corticosteroid, prednisone.
F decreases the effect of cortisone by metabolism alteration.
Fosphenytoin The enzyme inducer, fosphenytoin, may decrease the effect of the corticosteroid, prednisone.
Glycerol Phenylbutyrate Use of corticosteroids may cause the breakdown of body protein and increase plasma ammonia levels. Monitor ammonia levels closely when corticosteroids and glycerol pehnylbutyrate are used concomitantly.
Heptabarbital The barbiturate, heptabarbital, may decrease the effect of the corticosteroid, prednisone.
Hexobarbital The barbiturate, hexobarbital, may decrease the effect of the corticosteroid, prednisone.
Indacaterol Concomitant therapy may increase the risk of hypokalemia via intracellular shunting. Monitor for adverse effects and especially for cardiovascular effects associated with hypokalemia.
Insulin Lispro Concomitant therapy with corticosteriods may reduce the blood-glucose-lowering effect of insulin lispro.
Itraconazole The imidazole, itraconazole, may increase the effect and toxicity of the corticosteroid, prednisone.
Ketoconazole The imidazole, ketoconazole, may increase the effect and toxicity of the corticosteroid, prednisone.
Linagliptin CYP3A4 inducers may decrease levels of linagliptin and diminish the hypoglycemic effect of antidiabetic agents. Monitor concomitant therapy closely.
Magnesium salicylate The corticosteroid, prednisolone, may decrease the effect of magnesium salicylate.
Mephenytoin The enzyme inducer, mephenytoin, may decrease the effect of the corticosteroid, prednisone.
Mestranol The estrogenic agent, mestranol, may increase the effect of corticosteroid, prednisone.
Methohexital The barbiturate, methohexital, may decrease the effect of the corticosteroid, prednisone.
Methylphenobarbital The barbiturate, methylphenobarbital, may decrease the effect of the corticosteroid, prednisone.
Midodrine Increased arterial pressure
Neostigmine The corticosteroid, prednisone, may decrease the effect of the anticholinesterase, neostigmine.
Pentobarbital The barbiturate, pentobarbital, may decrease the effect of the corticosteroid, prednisone.
Phenobarbital The barbiturate, phenobarbital, may decrease the effect of the corticosteroid, prednisone.
Phenytoin The enzyme inducer, phenytoin, may decrease the effect of the corticosteroid, prednisone.
Primidone The barbiturate, primidone, may decrease the effect of the corticosteroid, prednisone.
Pyridostigmine The corticosteroid, prednisone, may decrease the effect of the anticholinesterase, pyridostigmine.
Quinestrol The estrogenic agent, quinestrol, may increase the effect of corticosteroid, prednisone.
Quinidine barbiturate The barbiturate, quinidine barbiturate, may decrease the effect of the corticosteroid, prednisone.
Rifampin The enzyme inducer, rifampin, may decrease the effect of the corticosteroid, prednisone.
Salicylate-sodium The corticosteroid, prednisone, may decrease the effect of the salicylate, salicylate-sodium.
Salsalate The corticosteroid, prednisone, may decrease the effect of the salicylate, salsalate.
Secobarbital The barbiturate, secobarbital, may decrease the effect of the corticosteroid, prednisone.
Tacrine Tacrine and Prednisone may independently exacerbate muscle weakness in myasthenia gravis patients. Monitor for additive muscle weakness effects.
Talbutal The barbiturate, talbutal, may decrease the effect of the corticosteroid, prednisone.
Trastuzumab Trastuzumab may increase the risk of neutropenia and anemia. Monitor closely for signs and symptoms of adverse events.
Trisalicylate-choline The corticosteroid, prednisone, may decrease the effect of the salicylate, trisalicylate-choline.
Vecuronium Vecuronium may increase the adverse neuromuscular effects of systemic corticosteroids, such as Prednisone. Monitor for increased muscle weakness and signs of polyneuropathies and myopathy.
Warfarin The corticosteroid, prednisone, alters the anticoagulant effect of warfarin.
Food Interactions
  • When Rayos, the delayed-release tablet, is taken without food, Cmax and bioavailability were lower compared to the fed state.
  • Take with food to reduce irritation.
  • Avoid alcohol.
  • Avoid taking with grapefruit juice.

Targets


Glucocorticoid receptor
Name Glucocorticoid receptor
Gene Name NR3C1
Pharmacological action yes
Actions agonist
References
  • Liu BG, Li ZY, Du M: [Effects of jingui shenqi pill combined prednisone on expression of glucocorticoid receptor and its clinical effect in treating bullous pemphigoid patients] Zhongguo Zhong Xi Yi Jie He Za Zhi. 2006 Oct;26(10):881-4. - Pubmed
  • Friel PN, Alexander T, Wright JV: Suppression of adrenal function by low-dose prednisone: assessment with 24-hour urinary steroid hormone profiles--a review of five cases. Altern Med Rev. 2006 Mar;11(1):40-6. - Pubmed
  • Diez JJ, Iglesias P: Pharmacological therapy of Cushing's syndrome: drugs and indications. Mini Rev Med Chem. 2007 May;7(5):467-80. - Pubmed
  • Yano A, Fujii Y, Iwai A, Kawakami S, Kageyama Y, Kihara K: Glucocorticoids suppress tumor lymphangiogenesis of prostate cancer cells. Clin Cancer Res. 2006 Oct 15;12(20 Pt 1):6012-7. - Pubmed
  • Yano A, Fujii Y, Iwai A, Kageyama Y, Kihara K: Glucocorticoids suppress tumor angiogenesis and in vivo growth of prostate cancer cells. Clin Cancer Res. 2006 May 15;12(10):3003-9. - Pubmed
  • Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. - Pubmed
DTHybrid score 0.8234
Corticosteroid 11-beta-dehydrogenase isozyme 1
Name Corticosteroid 11-beta-dehydrogenase isozyme 1
Gene Name HSD11B1
Pharmacological action unknown
Actions ligand
References
  • Raza K, Hardy R, Cooper MS: The 11beta-hydroxysteroid dehydrogenase enzymes--arbiters of the effects of glucocorticoids in synovium and bone. Rheumatology (Oxford). 2010 Nov;49(11):2016-23. doi: 10.1093/rheumatology/keq212. Epub 2010 Jul 15. - Pubmed
DTHybrid score 1.3667

Enzymes


Cytochrome P450 3A4
Name Cytochrome P450 3A4
Gene Name CYP3A4
Actions substrate,inhibitor,inducer
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.5318
Cytochrome P450 2C19
Name Cytochrome P450 2C19
Gene Name CYP2C19
Actions inducer
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.2818

Transporters


Multidrug resistance protein 1
Name Multidrug resistance protein 1
Gene Name ABCB1
Actions substrate,inhibitor
References
  • Nagy H, Goda K, Fenyvesi F, Bacso Z, Szilasi M, Kappelmayer J, Lustyik G, Cianfriglia M, Szabo G Jr: Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies. Biochem Biophys Res Commun. 2004 Mar 19;315(4):942-9. - Pubmed
  • Yates CR, Chang C, Kearbey JD, Yasuda K, Schuetz EG, Miller DD, Dalton JT, Swaan PW: Structural determinants of P-glycoprotein-mediated transport of glucocorticoids. Pharm Res. 2003 Nov;20(11):1794-803. - Pubmed
  • Dilger K, Schwab M, Fromm MF: Identification of budesonide and prednisone as substrates of the intestinal drug efflux pump P-glycoprotein. Inflamm Bowel Dis. 2004 Sep;10(5):578-83. - Pubmed
DTHybrid score 0.3929
Solute carrier organic anion transporter family member 1A2
Name Solute carrier organic anion transporter family member 1A2
Gene Name SLCO1A2
Actions inhibitor
References
  • Bossuyt X, Muller M, Hagenbuch B, Meier PJ: Polyspecific drug and steroid clearance by an organic anion transporter of mammalian liver. J Pharmacol Exp Ther. 1996 Mar;276(3):891-6. - Pubmed
DTHybrid score 0.2148

Carriers


Multidrug resistance protein 1
Name Multidrug resistance protein 1
Gene Name ABCB1
Actions
References Not Available
DTHybrid score 0.3929
Solute carrier organic anion transporter family member 1A2
Name Solute carrier organic anion transporter family member 1A2
Gene Name SLCO1A2
Actions
References Not Available
DTHybrid score 0.2148

Predictions


Id Partner name Gene Name Score
232 Corticosteroid-binding globulin SERPINA6 0.254
4757 Cytochrome P450 2C9 CYP2C9 0.2057
4119 Cytochrome P450 2D6 CYP2D6 0.1811
4118 Cytochrome P450 3A5 CYP3A5 0.1618
4924 Cytochrome P450 2C8 CYP2C8 0.161
4200 Cytochrome P450 1A2 CYP1A2 0.1491
6107 Cytochrome P450 3A7 CYP3A7 0.1082
6030 Cytochrome P450 2B6 CYP2B6 0.1011
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0843
6013 Cytochrome P450 2E1 CYP2E1 0.0814
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0793
2831 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase Not Available 0.0719
3059 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase fabG3 0.0719
6024 Cytochrome P450 1A1 CYP1A1 0.0674
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0639
1729 Solute carrier family 22 member 6 SLC22A6 0.063
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0621
20 Prostaglandin G/H synthase 1 PTGS1 0.0571
737 Mineralocorticoid receptor NR3C2 0.0571
862 Multidrug resistance-associated protein 1 ABCC1 0.0566
5718 Cytochrome P450 2A6 CYP2A6 0.0551
6142 Solute carrier family 22 member 8 SLC22A8 0.0515
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0486
290 Prostaglandin G/H synthase 2 PTGS2 0.0455
6145 Solute carrier family 22 member 1 SLC22A1 0.0452
469 Annexin A1 ANXA1 0.0449
776 Bile salt export pump ABCB11 0.0442
3811 Cytochrome P450 19A1 CYP19A1 0.0407
6143 Solute carrier family 22 member 7 SLC22A7 0.0379
136 Estrogen receptor ESR1 0.0376
6141 Sodium/bile acid cotransporter SLC10A1 0.0372
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0366
146 Androgen receptor AR 0.0358
614 Progesterone receptor PGR 0.0354
492 Histamine H1 receptor HRH1 0.0337
6106 Cytochrome P450 2C18 CYP2C18 0.0335
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0334
756 Sex hormone-binding globulin SHBG 0.0325
2164 Multidrug resistance-associated protein 4 ABCC4 0.032
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0318
824 Sodium-dependent serotonin transporter SLC6A4 0.0318
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0314
1024 Solute carrier family 22 member 11 SLC22A11 0.0306
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.03
6228 Nuclear receptor coactivator 1 NCOA1 0.0297
556 Alpha-1A adrenergic receptor ADRA1A 0.0293
6144 Solute carrier family 22 member 2 SLC22A2 0.0283
731 HIV-1 protease HIV-1 protease 0.0281
540 Sodium-dependent noradrenaline transporter SLC6A2 0.028
502 5-hydroxytryptamine 2A receptor HTR2A 0.027
831 D(2) dopamine receptor DRD2 0.0265
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0265
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0264
3923 Cholinesterase BCHE 0.0263
1898 Cytochrome P450 1B1 CYP1B1 0.0262
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0261
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0254
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0249
891 Dihydropteroate synthase folP 0.0236
5359 Dihydropteroate synthase folP 0.0236
7175 Dihydropteroate synthase sulI 0.0236
320 5-hydroxytryptamine 1A receptor HTR1A 0.0236
118 Organic cation/carnitine transporter 2 SLC22A5 0.0235
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0225
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0216
260 Cytochrome P450 51 ERG11 0.0216
761 Cytochrome P450 51 ERG11 0.0216
3163 Cytochrome P450 51 cyp51 0.0216
723 Cytosolic phospholipase A2 PLA2G4A 0.0216
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0214
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0211
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0211
4604 Liver carboxylesterase 1 CES1 0.0208
23 D(1A) dopamine receptor DRD1 0.0206
632 Alpha-1B adrenergic receptor ADRA1B 0.0199
33 Cystine/glutamate transporter SLC7A11 0.0193
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0192
244 Angiotensin-converting enzyme ACE 0.0192
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0191
847 Mu-type opioid receptor OPRM1 0.019
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0187
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0184
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0184
766 Beta-2 adrenergic receptor ADRB2 0.0179
904 Glutathione S-transferase P GSTP1 0.0178
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0176
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0175
1389 Transforming growth factor beta-1 TGFB1 0.0169
193 Beta-1 adrenergic receptor ADRB1 0.0169
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0167
467 Delta-type opioid receptor OPRD1 0.0164
318 Alpha-2A adrenergic receptor ADRA2A 0.0163
468 Cytochrome P450 4A11 CYP4A11 0.0162
696 Kappa-type opioid receptor OPRK1 0.0157
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0155
380 Cytochrome P450 17A1 CYP17A1 0.0154
869 Estrogen receptor beta ESR2 0.0154
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0149
3941 Amine oxidase [flavin-containing] A MAOA 0.0148
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0145
373 Transthyretin TTR 0.0145
6031 Cytochrome P450 3A43 CYP3A43 0.0145
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0145
6541 Peptostreptococcal albumin-binding protein pab 0.0142
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0142
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.0142
381 Prolactin receptor PRLR 0.0142
789 Alpha-1D adrenergic receptor ADRA1D 0.0141
238 Peroxisome proliferator-activated receptor gamma PPARG 0.014
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0139
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0139
341 5-hydroxytryptamine 3 receptor HTR3A 0.0138
844 Epidermal growth factor receptor EGFR 0.0137
122 P2Y purinoceptor 12 P2RY12 0.0136
833 Organic cation/carnitine transporter 1 SLC22A4 0.0133
6148 Multidrug resistance-associated protein 7 ABCC10 0.0133
885 5-hydroxytryptamine 1B receptor HTR1B 0.0133
713 Sodium-dependent dopamine transporter SLC6A3 0.0132
590 5-hydroxytryptamine 2C receptor HTR2C 0.0131
817 DNA topoisomerase 2-alpha TOP2A 0.013
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.013
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.0129
738 Monocarboxylate transporter 1 SLC16A1 0.0128
725 5-hydroxytryptamine 1D receptor HTR1D 0.0126
3587 Gastrotropin FABP6 0.0123
6147 Solute carrier family 22 member 3 SLC22A3 0.0121
6182 Cytochrome P450 2J2 CYP2J2 0.012
6136 Multidrug resistance-associated protein 5 ABCC5 0.0119
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0116
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0115
6137 Multidrug resistance-associated protein 6 ABCC6 0.0115
594 Thyroxine-binding globulin SERPINA7 0.0113
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0113
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.011
70 Type-1 angiotensin II receptor AGTR1 0.0109
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0106
2751 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0105
4755 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0105
758 Thyroid hormone receptor alpha THRA 0.0105
2211 Fatty acid-binding protein, heart FABP3 0.0105
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0105
6085 Fatty acid-binding protein, intestinal FABP2 0.0104
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0103
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0103
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0103
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0103
124 Histamine H2 receptor HRH2 0.0102
465 Calmodulin CALM1 0.0102
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0102
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.0099
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0099
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.0099
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0099
818 50S ribosomal protein L10 rplJ 0.0098
638 D(3) dopamine receptor DRD3 0.0097
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0097
629 Alpha-2B adrenergic receptor ADRA2B 0.0097
3671 7-alpha-hydroxysteroid dehydrogenase hdhA 0.0096
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0096
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0096
3939 Amine oxidase [flavin-containing] B MAOB 0.0095
566 Serotransferrin TF 0.0094
4237 50S ribosomal protein L22 rplV 0.0094
346 Thyroid hormone receptor beta-1 THRB 0.0094
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0094
4120 NADPH--cytochrome P450 reductase POR 0.0093
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0093
161 Tubulin beta chain TUBB 0.0093
312 Tubulin beta chain TUB2 0.0093
4615 Chain A, Red Copper Protein Nitrosocyanin NE0143 0.0093
436 5-hydroxytryptamine 2B receptor HTR2B 0.0093
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0092
474 Acetylcholinesterase ACHE 0.0091
183 Vascular endothelial growth factor A VEGFA 0.0089
952 Dipeptidyl peptidase 4 DPP4 0.0089
705 Glutamate receptor 1 GRIA1 0.0085
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0085
1517 Beta-3 adrenergic receptor ADRB3 0.0084
4148 Serine/threonine-protein kinase mTOR MTOR 0.0083
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0083
4238 50S ribosomal protein L4 rplD 0.0082
5578 50S ribosomal protein L4 rplD 0.0082
6173 50S ribosomal protein L4 rplD 0.0082
6219 50S ribosomal protein L4 rplD 0.0082
811 Translocator protein TSPO 0.0081
378 Alpha-2C adrenergic receptor ADRA2C 0.0081
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.008
198 Sodium channel protein type 10 subunit alpha SCN10A 0.008
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.008
6525 Group IID secretory phospholipase A2 PLA2G2D 0.008
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.008
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0079
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0079
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.0079
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.0079
558 Solute carrier family 12 member 1 SLC12A1 0.0079
6167 Organic solute transporter subunit beta OSTB 0.0079
6166 Organic solute transporter subunit alpha OSTA 0.0079
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0079
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0078
482 Glycine receptor subunit alpha-1 GLRA1 0.0078
645 Penicillin-binding protein 1A mrcA 0.0078
5805 Penicillin-binding protein 1A ponA 0.0078
6185 Penicillin-binding protein 1A mrcA 0.0078
6799 Penicillin-binding protein 1A pbpA 0.0078
442 Envelope glycoprotein gp41 0.0078
4859 Envelope glycoprotein env 0.0078
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0077
504 Mast/stem cell growth factor receptor KIT 0.0077
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0077
241 Calcium-transporting ATPase type 2C member 1 ATP2C1 0.0077
777 Tumor necrosis factor TNF 0.0076
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0076
6043 Putative G-protein coupled receptor 44 GPR44 0.0075
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0075
1656 CYP2B protein CYP2B 0.0073
537 ATP synthase delta chain, mitochondrial ATP5D 0.0073
543 Penicillin-binding protein 1B mrcB 0.0072
6186 Penicillin-binding protein 1B ponB 0.0072
6822 Penicillin-binding protein 1b pbp1b 0.0072
6844 Penicillin-binding protein 1b pbp1b 0.0072
1353 DNA topoisomerase 1 TOP1 0.0072
3552 DNA topoisomerase 1 topA 0.0072
2300 Lysozyme E 0.0072
3633 Lysozyme R 0.0072
5597 Lysozyme 17 0.0072
1 Peptidoglycan synthetase ftsI ftsI 0.0071
4155 Peptidoglycan synthetase ftsI ftsI 0.0071
6500 Phospholipase A2 PLA2G1B 0.007
6149 Solute carrier family 22 member 10 SLC22A10 0.007
26 Vascular endothelial growth factor receptor 3 FLT4 0.007
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0069
716 5-hydroxytryptamine 7 receptor HTR7 0.0069
1758 GTPase HRas HRAS 0.0068
407 Vascular endothelial growth factor receptor 2 KDR 0.0068
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0068
4210 Toll-like receptor 4 TLR4 0.0067
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0067
32 Vascular endothelial growth factor receptor 1 FLT1 0.0066
36 Insulin receptor INSR 0.0066
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0066
199 Monocarboxylate transporter 8 SLC16A2 0.0066
29 Tubulin beta-1 chain TUBB1 0.0066
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0065
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0065
1192 Sulfotransferase 1A1 SULT1A1 0.0065
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0064
1291 cAMP response element-binding protein CREB1 0.0064
606 Cytochrome P450 27, mitochondrial CYP27A1 0.0064
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0064
365 Dihydrofolate reductase DHFR 0.0063
2381 Dihydrofolate reductase DFR1 0.0063
2833 Dihydrofolate reductase Not Available 0.0063
2931 Dihydrofolate reductase folA 0.0063
3544 Dihydrofolate reductase folA 0.0063
3682 Dihydrofolate reductase folA 0.0063
6642 Dihydrofolate reductase folA 0.0063
6756 Dihydrofolate reductase dfrA 0.0063
3432 Multidrug-efflux transporter 1 regulator bmrR 0.0063
4476 Mannitol dehydrogenase mtlD 0.0063
1119 Peroxiredoxin-5, mitochondrial PRDX5 0.0063
228 Beta platelet-derived growth factor receptor PDGFRB 0.0063
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0062
6102 Arylamine N-acetyltransferase 2 NAT2 0.0062
432 D(4) dopamine receptor DRD4 0.0062
6014 Cytochrome P450 2A13 CYP2A13 0.0062
768 FK506-binding protein 1A FKBP1A 0.0062
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.006
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.006
511 5-hydroxytryptamine 1F receptor HTR1F 0.006
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.006
185 Vasopressin V1a receptor AVPR1A 0.006
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0059
633 Penicillin-binding proteins 1A/1B pbpA 0.0059
1010 Cytochrome P450 51A1 CYP51A1 0.0059
2539 Tubulin alpha-1 chain TUBA4A 0.0059
6220 Aryl hydrocarbon receptor AHR 0.0059
3382 Glycolipid transfer protein GLTP 0.0058
322 Vasopressin V2 receptor AVPR2 0.0058
68 Cannabinoid receptor 1 CNR1 0.0058
3932 Glutathione S-transferase A2 GSTA2 0.0057
259 Microsomal triglyceride transfer protein large subunit MTTP 0.0057
2449 Tubulin alpha-3 chain TUBA1A 0.0056
592 Carbonic anhydrase 4 CA4 0.0055
6020 Aldehyde oxidase AOX1 0.0055
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0055
477 DNA topoisomerase 4 subunit A parC 0.0054
886 DNA topoisomerase 4 subunit A parC 0.0054
6226 DNA topoisomerase 4 subunit A parC 0.0054
404 DNA gyrase subunit A gyrA 0.0053
6224 DNA gyrase subunit A gyrA 0.0053
102 DNA topoisomerase I, mitochondrial TOP1MT 0.0053
2853 14 kDa fatty acid-binding protein Not Available 0.0053
6033 High affinity interleukin-8 receptor A CXCR1 0.0053
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0052
49 Endothelin B receptor EDNRB 0.0052
2183 Fatty acid-binding protein, adipocyte FABP4 0.0052
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.0051
357 Carbonic anhydrase 2 CA2 0.0051
84 Nuclear receptor 0B1 NR0B1 0.0051
2616 Ganglioside GM2 activator GM2A 0.0051
2499 Tubulin beta-2C chain TUBB2C 0.0051
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.005
6027 Alkaline phosphatase, tissue-nonspecific isozyme ALPL 0.005
6432 Transporter snf 0.0049
578 Endothelin-1 receptor EDNRA 0.0049
6169 ATP-binding cassette sub-family A member 5 ABCA5 0.0048
6184 D-alanyl-D-alanine carboxypeptidase dacC dacC 0.0048
284 DNA-directed RNA polymerase beta chain rpoB 0.0048
5773 DNA-directed RNA polymerase beta chain rpoB 0.0048
3947 Xanthine dehydrogenase/oxidase XDH 0.0048
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0048
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0048
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0048
750 Voltage-dependent calcium channel gamma-1 subunit CACNG1 0.0047
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0047
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0047
5300 Antigen peptide transporter 1 TAP1 0.0047
459 Retinoic acid receptor RXR-alpha RXRA 0.0047
683 Potassium transporter GK0582 0.0047
24 Thymidylate synthase TMP1 0.0046
359 Thymidylate synthase TYMS 0.0046
2626 Thymidylate synthase thyA 0.0046
2729 Thymidylate synthase thyA 0.0046
5352 Thymidylate synthase THYA 0.0046
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0046
5934 Cytochrome P450 26A1 CYP26A1 0.0046
528 5-hydroxytryptamine 1E receptor HTR1E 0.0045
3781 Thiol:disulfide interchange protein dsbC precursor dsbC 0.0045
5449 Hypothetical gliding protein mglB 0.0045
5443 UPF0189 protein ymdB ymdB 0.0045
5440 UPF0067 protein yebR yebR 0.0045
2720 Copper-containing nitrite reductase nirK 0.0045
6151 Monocarboxylate transporter 10 SLC16A10 0.0045
5439 33 kDa chaperonin hslO 0.0045
5448 Ribonuclease Z rnz 0.0045
5446 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase HI_1679 0.0045
4705 Manganese catalase Not Available 0.0045
5447 Lethal(3)malignant brain tumor-like protein L3MBTL1 0.0045
5454 Internalin-A inlA 0.0045
80 Peroxisome proliferator-activated receptor alpha PPARA 0.0045
115 Penicillin-binding protein 2 mrdA 0.0044
6069 Penicillin-binding protein 2 mrdA 0.0044
6118 Penicillin-binding protein 2 penA 0.0044
6187 Penicillin-binding protein 2 pbpA 0.0044
6686 Penicillin-binding protein 2 pbp2 0.0044
6939 Penicillin-binding protein 2 mrdA 0.0044
7163 Penicillin-binding protein 2 pbpA 0.0044
1618 High affinity nerve growth factor receptor NTRK1 0.0044
571 Melatonin receptor type 1A MTNR1A 0.0044
362 Melatonin receptor type 1B MTNR1B 0.0044
2178 Metabotropic glutamate receptor 5 GRM5 0.0044
5645 DNA topoisomerase 4 subunit B parE 0.0044
6227 DNA topoisomerase 4 subunit B parE 0.0044
887 DNA gyrase subunit B gyrB 0.0044
4150 DNA gyrase subunit B gyrB 0.0044
6225 DNA gyrase subunit B gyrB 0.0044
1630 Integrin beta-2 ITGB2 0.0043
273 Apoptosis regulator Bcl-2 BCL2 0.0043
427 Substance-P receptor TACR1 0.0043
5787 Angiopoietin-1 receptor TEK 0.0043
6138 Multidrug resistance protein 3 ABCB4 0.0043
976 Platelet glycoprotein IX GP9 0.0043
1050 Bile salt sulfotransferase SULT2A1 0.0042
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0042
856 Vitamin D3 receptor VDR 0.0042
65 Matrix metalloproteinase-9 Not Available 0.0042
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0042
1852 Microtubule-associated protein 2 MAP2 0.0042
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0041
163 D(1B) dopamine receptor DRD5 0.0041
6068 Guanylate cyclase soluble subunit alpha-2 GUCY1A2 0.0041
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0041
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0041
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0041
3997 Cytochrome P450 24A1, mitochondrial CYP24A1 0.0041
597 Dihydropteridine reductase QDPR 0.004
295 Carbonic anhydrase 1 CA1 0.004
2021 Thrombomodulin THBD 0.004
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.004
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.004
276 Sodium- and chloride-dependent GABA transporter 1 SLC6A1 0.004
4122 Histone deacetylase 2 HDAC2 0.004
6508 Putative uncharacterized protein srtB 0.004
6543 Putative uncharacterized protein tcp14 0.004
6615 Putative uncharacterized protein MT0785 0.004
6623 Putative uncharacterized protein Not Available 0.004
6806 Putative uncharacterized protein AGR_C_2535 0.004
6813 Putative uncharacterized protein SAV4671 0.004
6815 Putative uncharacterized protein AFE_1514 0.004
6819 Putative uncharacterized protein RUMGNA_03254 0.004
6825 Putative uncharacterized protein CV_3270 0.004
4161 Furin FURIN 0.004
4498 Ornithine cyclodeaminase PP3533 0.004
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.004
4771 Dissimilatory copper-containing nitrite reductase nir 0.0039
5450 Prolyl endopeptidase Pep pep 0.0039
814 Ryanodine receptor 1 RYR1 0.0039
2714 Chorismate mutase aroH 0.0039
4611 Chorismate mutase aroG 0.0039
3356 Diaminopimelate decarboxylase lysA 0.0039
3274 Hydroxylamine reductase hcp 0.0039
4804 Hydroxylamine reductase hcp 0.0039
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0039
1129 C-C chemokine receptor type 5 CCR5 0.0039
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0039
6067 Penicillin binding protein 2a mecA 0.0038
6677 Myelin P2 protein PMP2 0.0038
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0038
239 Coagulation factor X F10 0.0038
85 Growth hormone receptor GHR 0.0038
319 Opioid receptor, sigma 1 OPRS1 0.0037
7 Nitric oxide synthase, inducible NOS2 0.0037
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0037
3426 Glutamine synthetase glnA 0.0037
3987 Glutamine synthetase GLUL 0.0037
780 Retinoic acid receptor RXR-gamma RXRG 0.0037
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0037
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.0037
1525 Heparin-binding growth factor 2 FGF2 0.0037
921 Glutamate receptor 2 GRIA2 0.0037
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0037
1256 5-hydroxytryptamine 6 receptor HTR6 0.0037
3736 Glyceraldehyde-3-phosphate dehydrogenase A gapA 0.0037
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0036
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0036
3697 Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase glmU 0.0036
3399 Limonene-1,2-epoxide hydrolase limA 0.0036
6218 Pannexin-1 PANX1 0.0036
3462 Tyrosine-protein kinase transforming protein Abl ABL 0.0036
4103 Proteasome subunit beta type 2 PSMB2 0.0036
4102 Proteasome subunit beta type 5 PSMB5 0.0036
4101 Proteasome subunit beta type 1 PSMB1 0.0036
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0036
819 Penicillin-binding protein 4 dacB 0.0036
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0035
444 Alcohol dehydrogenase 1B ADH1B 0.0035
6044 Serum paraoxonase/lactonase 3 PON3 0.0035
4608 Putative cytochrome P450 SCO1207 0.0035
4963 Putative cytochrome P450 SCO2884 0.0035
6254 Putative cytochrome P450 SCO6998 0.0035
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0035
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0035
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0035
939 50S ribosomal protein L3 rplC 0.0035
2981 Phospholipase A2, membrane associated PLA2G2A 0.0035
88 Retinoic acid receptor RXR-beta RXRB 0.0034
5180 L(+)-mandelate dehydrogenase mdlB 0.0034
3500 Putative family 31 glucosidase yicI yicI 0.0034
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.0034
596 3-oxo-5-alpha-steroid 4-dehydrogenase 1 SRD5A1 0.0033
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0033
233 Potassium channel subfamily K member 2 KCNK2 0.0033
1992 Vitamin D-binding protein GC 0.0033
1483 Membrane copper amine oxidase AOC3 0.0033
6501 Fatty acid-binding protein, liver FABP1 0.0033
572 Integrin alpha-L ITGAL 0.0033
707 72 kDa type IV collagenase MMP2 0.0033
1615 Chymase CMA1 0.0032
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0032
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0032
1867 Major prion protein PRNP 0.0032
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0032
3480 Mannan endo-1,4-beta-mannosidase manA 0.0032
822 Aldose reductase AKR1B1 0.0032
2107 Microtubule-associated protein 1A MAP1A 0.0032
595 Fibrinogen alpha chain FGA 0.0032
140 30S ribosomal protein S9 rpsI 0.0031
6719 30S ribosomal protein S9 rpsI 0.0031
6725 30S ribosomal protein S9 rpsI 0.0031
2597 Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] glmS 0.0031
577 Argininosuccinate lyase ASL 0.0031
990 Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 0.0031
3760 Penicillin-binding protein 5 precursor dacA 0.0031
2578 Tubulin beta-3 chain TUBB3 0.003
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.003
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.003
2285 Streptogramin A acetyltransferase vatD 0.003
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.003
4217 Telomerase reverse transcriptase TERT 0.003
741 Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 0.003
6042 Prostaglandin reductase 2 PTGR2 0.003
106 Cannabinoid receptor 2 CNR2 0.003
287 Beta-1,4-galactosyltransferase 1 B4GALT1 0.003
6174 50S ribosomal protein L32 rpmF 0.0029
1714 Mitogen-activated protein kinase 3 MAPK3 0.0029
6103 Arylamine N-acetyltransferase 1 NAT1 0.0029
3813 Fibrinogen gamma chain FGG 0.0029
3812 Fibrinogen beta chain [Contains: Fibrinopeptide B] FGB 0.0029
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0029
1629 Transcription factor AP-1 JUN 0.0029
823 Fibroblast growth factor receptor 2 FGFR2 0.0029
165 FL cytokine receptor FLT3 0.0029
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0029
663 Solute carrier family 12 member 4 SLC12A4 0.0029
53 Solute carrier family 12 member 5 SLC12A5 0.0029
3809 Estrogen-related receptor gamma ESRRG 0.0028
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.0028
1435 Synaptic vesicle glycoprotein 2A SV2A 0.0028
666 NADP-dependent malic enzyme ME1 0.0028
3772 3-oxoacyl-[acyl-carrier-protein] reductase fabG 0.0028
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.0028
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.0028
5157 Dehydrogenase/reductase SDR family member 11 DHRS11 0.0028
646 Malate dehydrogenase, cytoplasmic MDH1 0.0028
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0028
5326 Oxidoreductase, short chain dehydrogenase/reductase family TM_0441 0.0028
5346 Oxidoreductase, aldo/keto reductase family TM_1009 0.0028
5332 MtdA bifunctional protein mtdA 0.0028
4403 Protein iolS iolS 0.0028
5330 General stress protein 69 yhdN 0.0028
5333 Alcohol dehydrogenase, iron-containing TM_0920 0.0028
3778 NAD(P) transhydrogenase subunit beta pntB 0.0028
5343 NADP-dependent fatty aldehyde dehydrogenase aldH 0.0028
5322 Oxidoreductase ydhF ydhF 0.0028
5342 NADH-dependent butanol dehydrogenase, putative TM_0820 0.0028
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0028
1792 Tissue-type plasminogen activator PLAT 0.0028
11 NAD(P) transhydrogenase, mitochondrial NNT 0.0028
6207 30S ribosomal protein S14 rpsN 0.0028
6209 30S ribosomal protein S19 rpsS 0.0028
6712 30S ribosomal protein S19 rpsS 0.0028
6726 30S ribosomal protein S19 rpsS 0.0028
1278 Pro-epidermal growth factor EGF 0.0028
489 Monocarboxylate transporter 2 SLC16A7 0.0027
3810 Catechol O-methyltransferase COMT 0.0027
6232 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short GNAS 0.0027
6233 Adenylate cyclase type 2 ADCY2 0.0027
6234 Adenylate cyclase type 5 ADCY5 0.0027
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0027
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.0027
1757 Myeloperoxidase MPO 0.0027
4173 Tyrosine-protein kinase JAK2 JAK2 0.0027
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0027
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0027
275 Arachidonate 5-lipoxygenase ALOX5 0.0027
889 3-oxoacyl-[acyl-carrier-protein] synthase 1 fabB 0.0027
6860 3-oxoacyl-[acyl-carrier-protein] synthase 1 kasA 0.0027
310 Solute carrier family 12 member 2 SLC12A2 0.0027
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0026
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0026
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0026
6824 Tyrosine-protein kinase Lyn LYN 0.0026
6599 HTH-type transcriptional regulator ttgR ttgR 0.0026
605 Fumarate reductase flavoprotein subunit frdA 0.0026
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0026
3673 Fumarate reductase flavoprotein subunit fccA 0.0026
4912 Fumarate reductase flavoprotein subunit ifcA 0.0026
6549 Fumarate reductase flavoprotein subunit frdA 0.0026
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0026
6126 Carbonic anhydrase 7 CA7 0.0026
1178 Adenosine A2a receptor ADORA2A 0.0026
5997 Tumor necrosis factor ligand superfamily member 11 TNFSF11 0.0026
1385 Angiotensin-converting enzyme 2 ACE2 0.0025
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0025
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0025
4252 Penicillin-binding protein 5 dacA 0.0025
229 Retinoic acid receptor beta RARB 0.0025
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0025
162 Retinoic acid receptor gamma-1 RARG 0.0025
2375 ADP-L-glycero-D-manno-heptose-6-epimerase hldD 0.0025
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0025
5073 Ferredoxin--NADP reductase petH 0.0025
5076 Ferredoxin--NADP reductase fpr 0.0025
5119 Ferredoxin--NADP reductase petH 0.0025
5121 Ferredoxin--NADP reductase fpr 0.0025
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0025
5818 Folate receptor alpha FOLR1 0.0024
989 L-xylulose reductase DCXR 0.0024
730 Retinoic acid receptor alpha RARA 0.0024
4582 Putative pteridine reductase 2 ptr2 0.0024
4628 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase gapN 0.0024
2636 Shikimate dehydrogenase aroE 0.0024
3515 Shikimate dehydrogenase aroE 0.0024
5328 Prostaglandin F synthase Tb11.02.2310 0.0024
3446 NADP-dependent alcohol dehydrogenase adh 0.0024
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.0024
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.0024
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0024
2305 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 0.0024
2286 Isocitrate dehydrogenase [NADP] icd 0.0024
2302 Isocitrate dehydrogenase [NADP] icd 0.0024
2771 Isocitrate dehydrogenase [NADP] icd 0.0024
581 Cytochrome P450 2R1 CYP2R1 0.0024
4311 tRNA TRDMT1 0.0024
4325 tRNA trmD 0.0024
4328 tRNA trmD 0.0024
3616 Fatty acid-binding protein, epidermal FABP5 0.0024
5431 Lipid binding protein Not Available 0.0024
5433 UPF0230 protein TM_1468 TM_1468 0.0024
5430 Hepatocyte nuclear factor 4-gamma HNF4G 0.0024
544 Potassium voltage-gated channel subfamily E member 1 KCNE1 0.0024
159 Penicillin-binding protein 2B penA 0.0024
6121 Penicillin-binding protein 2B penA 0.0024
6039 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A PDE11A 0.0024
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.0024
654 Flavin reductase BLVRB 0.0024
2320 Thymidine kinase, cytosolic TK1 0.0024
6231 Pepsin A PGA3 0.0024
5852 Type-2 angiotensin II receptor AGTR2 0.0024
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0024
6459 Glycodelin PAEP 0.0024
5432 Trafficking protein particle complex subunit 3 TRAPPC3 0.0024
1770 Phospholipase C PLCL1 0.0024
2841 Phospholipase C plc 0.0024
1759 85 kDa calcium-independent phospholipase A2 PLA2G6 0.0024
517 Alcohol dehydrogenase 1C ADH1C 0.0023
642 3-oxo-5-alpha-steroid 4-dehydrogenase 2 SRD5A2 0.0023
3917 Methylenetetrahydrofolate reductase MTHFR 0.0023
4221 Vascular endothelial growth factor VEGF 0.0023
5816 Cadherin-5 CDH5 0.0023
332 Beta-lactamase blaZ 0.0023
2478 Beta-lactamase ampC 0.0023
2613 Beta-lactamase ampC 0.0023
2635 Beta-lactamase ampC 0.0023
2700 Beta-lactamase penP 0.0023
5445 Beta-lactamase blaB 0.0023
6019 Beta-lactamase SHV-7 0.0023
6701 Beta-lactamase cphA 0.0023
1313 Lactoylglutathione lyase GLO1 0.0023
1864 RET proto-oncogene RET 0.0023
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0023
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0023
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0023
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0023
2207 Rhodopsin RHO 0.0023
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0023
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.0023
620 Bifunctional dihydrofolate reductase-thymidylate synthase Not Available 0.0023
2599 Tyrosine-protein kinase HCK HCK 0.0022
6297 Prostaglandin reductase 1 PTGR1 0.0022
4531 Putative ketoacyl reductase actIII 0.0022
6862 Aldo-keto reductase family 1 member B10 AKR1B10 0.0022
3062 Aspartate-semialdehyde dehydrogenase asd 0.0022
751 Potassium channel subfamily K member 6 KCNK6 0.0022
4773 Deoxycytidine kinase DCK 0.0022
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.0022
518 Peroxidase/catalase T katG 0.0022
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0021
298 Renin REN 0.0021
6506 Stathmin-4 STMN4 0.0021
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.0021
293 Gamma-glutamyl hydrolase GGH 0.0021
2675 Pteridine reductase 1 PTR1 0.0021
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0021
1124 Sepiapterin reductase SPR 0.0021
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0021
331 Retinol-binding protein I, cellular RBP1 0.0021
3876 Aromatic-L-amino-acid decarboxylase DDC 0.0021
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0021
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0021
4203 Histamine N-methyltransferase HNMT 0.002
3090 Chitosanase csn 0.002
4149 Nuclear factor NF-kappa-B p100 subunit NFKB2 0.002
283 SEC14-like protein 2 SEC14L2 0.002
172 Potassium channel subfamily K member 1 KCNK1 0.002
2159 Quinone oxidoreductase CRYZ 0.002
936 Ephrin type-A receptor 2 EPHA2 0.002
3856 Fibroblast growth factor receptor 3 FGFR3 0.002
6893 Calcium/calmodulin-dependent protein kinase type II gamma chain CAMK2G 0.002
6755 Poliovirus receptor PVR 0.002
4199 Sphingosine 1-phosphate receptor Edg-8 S1PR5 0.002
76 Nitric-oxide synthase, brain NOS1 0.002
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.002
5251 Carbonyl reductase [NADPH] 1 CBR1 0.002
3937 Fatty-acid amide hydrolase FAAH 0.0019
461 Glycine receptor subunit alpha-3 GLRA3 0.0019
1650 Heme carrier protein 1 SLC46A1 0.0019
54 Prothrombin F2 0.0019
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0019
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0019
1196 Complement decay-accelerating factor CD55 0.0019
1638 Solute carrier family 2, facilitated glucose transporter member 2 SLC2A2 0.0019
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0018
1253 Interferon gamma IFNG 0.0018
2112 Toll-like receptor 9 TLR9 0.0018
563 Thyroid peroxidase TPO 0.0018
5998 Toll-like receptor 8 TLR8 0.0018
712 Tubulin alpha chain TUB1 0.0018
1968 ATP-sensitive inward rectifier potassium channel 12 KCNJ12 0.0018
5923 Microtubule-associated protein tau MAPT 0.0018
5924 Microtubule-associated protein 4 MAP4 0.0018
565 Extracellular calcium-sensing receptor CASR 0.0018
3312 Fatty acid-binding protein, brain FABP7 0.0018
1198 Serum paraoxonase/arylesterase 1 PON1 0.0018
6223 Penicillin-binding protein 1C pbpC 0.0018
67 Prolyl 4-hydroxylase subunit alpha-1 P4HA1 0.0017
251 Alcohol dehydrogenase 1A ADH1A 0.0017
613 Atrial natriuretic peptide receptor A NPR1 0.0017
16 Adenosine A1 receptor ADORA1 0.0017
621 Periplasmic [Fe] hydrogenase 1 Not Available 0.0017
131 Synaptic vesicular amine transporter SLC18A2 0.0017
2391 Ferrochelatase hemH 0.0017
6502 Ferrochelatase DKFZp686P18130 0.0017
1591 Ferrochelatase, mitochondrial FECH 0.0017
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0017
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.0017
6100 BDNF/NT-3 growth factors receptor NTRK2 0.0017
634 Squalene monooxygenase SQLE 0.0017
7196 Squalene monooxygenase ERG1 0.0017
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0017
5878 Alpha-7 nicotinic cholinergic receptor subunit CHRFAM7A 0.0017
174 Sigma 1-type opioid receptor SIGMAR1 0.0017
144 Hemoglobin subunit alpha HBA1 0.0017
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0017
2808 Chloramphenicol acetyltransferase 3 cat3 0.0016
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0016
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.0016
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0016
6766 O-GlcNAcase BT_4395 BT_4395 0.0016
94 5-hydroxytryptamine 4 receptor HTR4 0.0016
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.0016
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.0016
890 Niemann-Pick C1-like protein 1 NPC1L1 0.0016
173 Toll-like receptor 7 TLR7 0.0016
2297 Genome polyprotein Not Available 0.0016
2322 Genome polyprotein Not Available 0.0016
2694 Genome polyprotein Not Available 0.0016
2719 Genome polyprotein Not Available 0.0016
2860 Genome polyprotein Not Available 0.0016
2928 Genome polyprotein Not Available 0.0016
3160 Genome polyprotein Not Available 0.0016
3260 Genome polyprotein Not Available 0.0016
4783 Genome polyprotein Not Available 0.0016
5726 Genome polyprotein Not Available 0.0016
5779 Genome polyprotein Not Available 0.0016
5867 Genome polyprotein Not Available 0.0016
6253 Genome polyprotein Not Available 0.0016
6301 Genome polyprotein Not Available 0.0016
6380 Genome polyprotein Not Available 0.0016
6381 Genome polyprotein Not Available 0.0016
6437 Genome polyprotein Not Available 0.0016
6520 Genome polyprotein Not Available 0.0016
6521 Genome polyprotein Not Available 0.0016
6652 Genome polyprotein Not Available 0.0016
6734 Genome polyprotein Not Available 0.0016
6735 Genome polyprotein Not Available 0.0016
6736 Genome polyprotein Not Available 0.0016
6737 Genome polyprotein Not Available 0.0016
6738 Genome polyprotein Not Available 0.0016
6739 Genome polyprotein Not Available 0.0016
6744 Genome polyprotein Not Available 0.0016
6748 Genome polyprotein Not Available 0.0016
6894 Genome polyprotein Not Available 0.0016
6898 Genome polyprotein Not Available 0.0016
3233 Bile acid receptor NR1H4 0.0015
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0015
4192 DNA topoisomerase 2-beta TOP2B 0.0015
702 UMP-CMP kinase CMPK1 0.0015
6146 High affinity copper uptake protein 1 SLC31A1 0.0015
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0015
3601 Dihydropteroate synthase 1 folP1 0.0015
3807 Dihydropteroate synthase 1 folP1 0.0015
3808 Dihydropteroate synthase 2 folP2 0.0015
2417 Chloramphenicol acetyltransferase cat 0.0015
3278 Chloramphenicol acetyltransferase cat 0.0015
3611 Cytidine deaminase cdd 0.0015
3707 Cytidine deaminase cdd 0.0015
4211 Cytidine deaminase CDA 0.0015
2810 Dr hemagglutinin structural subunit draA 0.0015
473 L-lactate dehydrogenase A chain LDHA 0.0015
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0015
6493 Cytochrome c oxidase subunit 6C COX6C 0.0015
6495 Cytochrome c oxidase subunit 7C, mitochondrial COX7C 0.0015
6496 Cytochrome c oxidase subunit 8A, mitochondrial COX8A 0.0015
6499 Cytochrome c oxidase polypeptide 7A1, mitochondrial COX7A1 0.0015
6494 Cytochrome c oxidase subunit 7B, mitochondrial COX7B 0.0015
6491 Cytochrome c oxidase subunit 5A, mitochondrial COX5A 0.0015
6498 Cytochrome c oxidase subunit 6B1 COX6B1 0.0015
6497 Cytochrome c oxidase subunit 6A2, mitochondrial COX6A2 0.0015
6489 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial COX4I1 0.0015
5793 Cytochrome c oxidase subunit 2 MT-CO2 0.0015
6559 Cytochrome c oxidase subunit 2 ctaC 0.0015
6669 Cytochrome c oxidase subunit 2 ctaC 0.0015
6490 Cytochrome c oxidase subunit 3 MT-CO3 0.0015
371 Cytochrome c oxidase subunit 1 MT-CO1 0.0015
6558 Cytochrome c oxidase subunit 1 ctaD 0.0015
6002 Prostaglandin E2 receptor EP4 subtype PTGER4 0.0015
153 Dopamine beta-hydroxylase DBH 0.0015
1569 G1/S-specific cyclin-D1 CCND1 0.0015
5798 Mitogen-activated protein kinase 11 MAPK11 0.0014
1541 Metalloproteinase mmp20 0.0014
3913 Glutamic acid decarboxylase GAD65 0.0014
476 RAC-alpha serine/threonine-protein kinase AKT1 0.0014
1760 Aminopeptidase N ANPEP 0.0014
6843 Aminopeptidase N pepN 0.0014
2129 Sucrase-isomaltase, intestinal SI 0.0014
1262 Corticotropin-lipotropin POMC 0.0014
6032 PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) fas 0.0014
117 Sterol O-acyltransferase 1 SOAT1 0.0014
4131 Prostaglandin E2 receptor, EP3 subtype PTGER3 0.0014
406 Prostaglandin E2 receptor, EP2 subtype PTGER2 0.0014
2540 Choloylglycine hydrolase cbh 0.0014
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.0014
6211 Tubulin epsilon chain TUBE1 0.0013
6212 Tubulin gamma-1 chain TUBG1 0.0013
6210 Tubulin delta chain TUBD1 0.0013
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0013
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0013
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0013
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0013
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0013
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0013
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0013
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0013
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0013
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0013
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0013
6131 Carbonic anhydrase 14 CA14 0.0013
164 Histamine H4 receptor HRH4 0.0013
1405 Thiopurine S-methyltransferase TPMT 0.0013
6116 Gastric triacylglycerol lipase LIPF 0.0012
3806 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A 0.0012
694 Matrix protein 2 M 0.0012
2240 Cell division protein kinase 2 CDK2 0.0012
3823 Cytokine receptor common gamma chain IL2RG 0.0012
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0012
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0012
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0012
338 DNA polymerase UL30 0.0012
379 DNA polymerase UL54 0.0012
697 DNA polymerase ORF28 0.0012
2482 DNA polymerase 43 0.0012
4104 DNA polymerase BALF5 0.0012
6122 Carbonic anhydrase 3 CA3 0.0012
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.0012
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.0012
1295 Fatty acid synthase FASN 0.0012
1360 Sphingomyelin phosphodiesterase SMPD1 0.0012
735 Alanine aminotransferase 1 GPT 0.0012
3904 Alanine aminotransferase 2 GPT2 0.0012
4226 Uridine phosphorylase 2 UPP2 0.0012
3957 Adenosine deaminase ADA 0.0012
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0012
6859 Protein S100-A4 S100A4 0.0012
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.0012
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0012
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0011
1768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit GNG2 0.0011
1268 Neuropeptide S receptor NPSR1 0.0011
1571 G protein-activated inward rectifier potassium channel 1 KCNJ3 0.0011
1581 G protein-activated inward rectifier potassium channel 2 KCNJ6 0.0011
291 Nitric-oxide synthase, endothelial NOS3 0.0011
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0011
484 Tyrosine-protein kinase ABL2 ABL2 0.0011
754 Pancreatic triacylglycerol lipase PNLIP 0.0011
4225 Uridine phosphorylase 1 UPP1 0.0011
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0011
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0011
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0011
896 Glutathione S-transferase Mu 1 GSTM1 0.0011
724 Interleukin-2 receptor alpha chain IL2RA 0.0011
717 Interleukin-2 receptor subunit beta IL2RB 0.0011
820 Glycine receptor subunit alpha-2 GLRA2 0.0011
1374 Natriuretic peptides B NPPB 0.001
1827 Gap junction alpha-1 protein GJA1 0.001
1908 Vascular cell adhesion protein 1 VCAM1 0.001
1810 Protein S100-A1 S100A1 0.001
6097 Protein S100-A2 S100A2 0.001
908 Glutathione S-transferase theta-1 GSTT1 0.001
4116 Dihydropteroate synthetase Not Available 0.001
4228 Keratin, type II cytoskeletal 7 KRT7 0.001
2461 D-alanyl-D-alanine carboxypeptidase Not Available 0.001
5756 D-alanyl-D-alanine carboxypeptidase dac 0.001
935 Proto-oncogene tyrosine-protein kinase Yes YES1 0.001
1063 Signal transducer and activator of transcription 5B STAT5B 0.001
2216 Fibroblast growth factor receptor 4 FGFR4 0.001
413 Amidophosphoribosyltransferase PPAT 0.001
2515 Amidophosphoribosyltransferase purF 0.001
3714 Amidophosphoribosyltransferase purF 0.001
6073 Potassium channel subfamily K member 9 KCNK9 0.001
6072 Potassium channel subfamily K member 3 KCNK3 0.001
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.001
1144 Hepatocyte growth factor receptor MET 0.001
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.001
215 Sodium channel protein type 11 subunit alpha SCN11A 0.001
493 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 0.001
2404 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PIK3CG 0.001
512 DNA-directed RNA polymerase alpha chain rpoA 0.001
5772 DNA-directed RNA polymerase alpha chain rpoA 0.001
4041 Microsomal glutathione S-transferase 2 MGST2 0.001
1176 Mitogen-activated protein kinase 1 MAPK1 0.001
2473 Tyrosine-protein kinase CSK CSK 0.001
2398 Tyrosine-protein kinase ZAP-70 ZAP70 0.001
2268 Cholesterol oxidase choB 0.0009
2822 Cholesterol oxidase choA 0.0009
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.0009
267 Plasminogen activator inhibitor 1 SERPINE1 0.0009
3830 Calreticulin CALR 0.0009
934 Proto-oncogene tyrosine-protein kinase Fyn FYN 0.0009
6048 Troponin C, skeletal muscle TNNC2 0.0009
6105 3-oxo-5-beta-steroid 4-dehydrogenase AKR1D1 0.0009
569 Retinal dehydrogenase 2 ALDH1A2 0.0009
3086 Plasmepsin-2 Not Available 0.0009
611 Retinal dehydrogenase 1 ALDH1A1 0.0009
360 Ribonucleoside-diphosphate reductase large subunit RRM1 0.0009
1048 Protein S100-A13 S100A13 0.0009
2226 Protein S100-A12 S100A12 0.0009
1648 Elastin ELN 0.0009
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0009
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0009
2283 Steroid Delta-isomerase ksi 0.0009
2920 Steroid Delta-isomerase ksi 0.0009
992 Protein tyrosine kinase 2 beta PTK2B 0.0009
208 DNA-directed RNA polymerase beta' chain rpoC 0.0009
5774 DNA-directed RNA polymerase beta' chain rpoC 0.0009
390 Adenosine A3 receptor ADORA3 0.0009
6171 Solute carrier family 28 member 3 SLC28A3 0.0009
6034 Hydroxyindole O-methyltransferase ASMT 0.0009
6035 Nuclear receptor ROR-beta RORB 0.0009
6036 Eosinophil peroxidase EPX 0.0009
2132 Protein S100-B S100B 0.0009
3404 Exotoxin A eta 0.0008
3639 Thymidine phosphorylase deoA 0.0008
3936 Thymidine phosphorylase TYMP 0.0008
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0008
6221 Steroid hormone receptor ERR1 ESRRA 0.0008
22 30S ribosomal protein S4 rpsD 0.0008
6714 30S ribosomal protein S4 rpsD 0.0008
2325 Sulfotransferase family cytosolic 2B member 1 SULT2B1 0.0008
810 Heme oxygenase 1 HMOX1 0.0008
3391 Heme oxygenase 1 pbsA1 0.0008
1039 Histone deacetylase 9 HDAC9 0.0008
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0008
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0008
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0008
816 Biliverdin reductase A BLVRA 0.0008
2298 Cytochrome P450-cam camC 0.0008
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.0008
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0008
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0008
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.0008
2232 Interleukin-5 IL5 0.0008
396 Alcohol dehydrogenase 4 ADH4 0.0008
328 Sorbitol dehydrogenase SORD 0.0008
363 NADP-dependent malic enzyme, mitochondrial ME3 0.0008
857 Malate dehydrogenase, mitochondrial MDH2 0.0008
1593 Mucin-2 MUC2 0.0008
4031 Glutathione S-transferase A1 GSTA1 0.0008
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0008
74 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial DLAT 0.0008
1649 Small inducible cytokine A2 CCL2 0.0008
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.0008
77 L-lactate dehydrogenase B chain LDHB 0.0008
2530 Protein kinase C theta type PRKCQ 0.0008
12 Alcohol dehydrogenase class 3 ADH5 0.0008
1025 Aquaporin-1 AQP1 0.0008
1275 Estrogen sulfotransferase SULT1E1 0.0008
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0008
2091 Endoplasmin HSP90B1 0.0008
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0007
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0007
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0007
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0007
765 Indoleamine 2,3-dioxygenase IDO1 0.0007
760 Fibroblast growth factor 1 FGF1 0.0007
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0007
607 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NDUFA2 0.0007
374 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NDUFB1 0.0007
555 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 0.0007
446 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NDUFA7 0.0007
104 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NDUFS6 0.0007
247 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUFA1 0.0007
343 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NDUFC1 0.0007
190 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 NDUFA4 0.0007
755 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NDUFA3 0.0007
353 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 NDUFA4L2 0.0007
609 15-hydroxyprostaglandin dehydrogenase [NAD+] HPGD 0.0007
272 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NDUFB10 0.0007
313 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NDUFB3 0.0007
384 NADH-ubiquinone oxidoreductase chain 6 MT-ND6 0.0007
300 NADH-ubiquinone oxidoreductase chain 4L MT-ND4L 0.0007
206 3-keto-steroid reductase HSD17B7 0.0007
475 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NDUFB2 0.0007
99 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NDUFS5 0.0007
270 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NDUFB5 0.0007
30 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NDUFV3 0.0007
372 Estradiol 17-beta-dehydrogenase 3 HSD17B3 0.0007
525 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NDUFA5 0.0007
219 NADH-ubiquinone oxidoreductase chain 3 MT-ND3 0.0007
141 3-hydroxyisobutyrate dehydrogenase, mitochondrial HIBADH 0.0007
236 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NDUFA6 0.0007
417 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NDUFB6 0.0007
324 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NDUFB4 0.0007
335 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NDUFA9 0.0007
568 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NDUFB7 0.0007
598 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NDUFA11 0.0007
152 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NDUFV2 0.0007
582 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NDUFA13 0.0007
829 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NDUFA12 0.0007
145 Corticosteroid 11-beta-dehydrogenase isozyme 2 HSD11B2 0.0007
602 Acyl carrier protein, mitochondrial NDUFAB1 0.0007
107 C-4 methylsterol oxidase SC4MOL 0.0007
405 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NDUFA8 0.0007
656 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 0.0007
729 GDP-L-fucose synthetase TSTA3 0.0007
3463 GDP-L-fucose synthetase fcl 0.0007
746 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NDUFB8 0.0007
167 L-lactate dehydrogenase C chain LDHC 0.0007
326 L-lactate dehydrogenase A-like 6A LDHAL6A 0.0007
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.0007
3726 D-3-phosphoglycerate dehydrogenase serA 0.0007
4291 D-3-phosphoglycerate dehydrogenase serA 0.0007
721 NADH-ubiquinone oxidoreductase chain 2 MT-ND2 0.0007
231 Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic GPD1 0.0007
271 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial ALDH4A1 0.0007
14 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial IDH3A 0.0007
50 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating NSDHL 0.0007
41 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NDUFS8 0.0007
112 L-lactate dehydrogenase A-like 6B LDHAL6B 0.0007
216 Aldehyde dehydrogenase 3B2 ALDH3B2 0.0007
616 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial IDH3B 0.0007
9 Estradiol 17-beta-dehydrogenase 2 HSD17B2 0.0007
628 Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial PDHA1 0.0007
848 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial IDH3G 0.0007
644 Heme oxygenase 2 HMOX2 0.0007
4982 Heme oxygenase 2 pbsA2 0.0007
91 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NDUFA10 0.0007
608 NADH-ubiquinone oxidoreductase chain 4 MT-ND4 0.0007
539 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NDUFV1 0.0007
496 Aldehyde dehydrogenase 3B1 ALDH3B1 0.0007
34 7-dehydrocholesterol reductase DHCR7 0.0007
662 Fatty aldehyde dehydrogenase ALDH3A2 0.0007
711 UDP-glucose 6-dehydrogenase UGDH 0.0007
3672 UDP-glucose 6-dehydrogenase hasB 0.0007
149 Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 0.0007
531 Aldehyde dehydrogenase X, mitochondrial ALDH1B1 0.0007
258 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial ALDH6A1 0.0007
487 Aldo-keto reductase family 1 member C4 AKR1C4 0.0007
637 NADH-ubiquinone oxidoreductase chain 5 MT-ND5 0.0007
196 D-beta-hydroxybutyrate dehydrogenase, mitochondrial BDH1 0.0007
671 Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial PDHA2 0.0007
643 Peroxisomal bifunctional enzyme EHHADH 0.0007
548 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NDUFS1 0.0007
288 Trifunctional enzyme subunit alpha, mitochondrial HADHA 0.0007
393 GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase H6PD 0.0007
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0007
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0007
130 Prostacyclin synthase PTGIS 0.0007
6316 ADP-ribosylation factor 1 ARF1 0.0007
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0007
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0007
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0007
6134 Sodium channel subunit beta-3 SCN3B 0.0007
6133 Sodium channel subunit beta-2 SCN2B 0.0007
6135 Sodium channel subunit beta-4 SCN4B 0.0007
6132 Sodium channel subunit beta-1 SCN1B 0.0007
6129 Carbonic anhydrase-related protein 11 CA11 0.0007
6127 Carbonic anhydrase-related protein CA8 0.0007
6128 Carbonic anhydrase-related protein 10 CA10 0.0007
2408 Tyrosine-protein kinase SYK SYK 0.0007
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0007
3221 Cytochrome c4 cc4 0.0007
2511 MAP kinase-activated protein kinase 2 MAPKAPK2 0.0007
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0007
2290 ADP-ribosyl cyclase 2 BST1 0.0007
13 Aminomethyltransferase, mitochondrial AMT 0.0007
226 Gonadotropin-releasing hormone receptor GNRHR 0.0007
1830 5'-nucleotidase NT5E 0.0007
6836 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial HIBCH 0.0007
6837 Serine/threonine-protein kinase 17B STK17B 0.0007
125 DNA polymerase beta POLB 0.0007
1123 Eosinophil cationic protein RNASE3 0.0007
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0006
296 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial MTHFD2 0.0006
6026 Alcohol dehydrogenase 6 ADH6 0.0006
248 Pyrroline-5-carboxylate reductase 1 PYCR1 0.0006
802 Pyrroline-5-carboxylate reductase 2 PYCR2 0.0006
627 11-cis retinol dehydrogenase RDH5 0.0006
640 Aldehyde dehydrogenase 1A3 ALDH1A3 0.0006
6241 Nuclear receptor coactivator 2 NCOA2 0.0006
342 P protein [Includes: DNA-directed DNA polymerase P 0.0006
612 P protein [Includes: DNA-directed DNA polymerase P 0.0006
110 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.0006
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.0006
6130 Carbonic anhydrase 13 CA13 0.0006
626 Cysteine dioxygenase type 1 CDO1 0.0006
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0006
677 Choline-phosphate cytidylyltransferase A PCYT1A 0.0006
3126 Poly [ADP-ribose] polymerase 1 PARP1 0.0006
57 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I HSD3B1 0.0006
6656 UDP-glucuronosyltransferase 3A1 UGT3A1 0.0006
6168 Solute carrier family 22 member 16 SLC22A16 0.0006
714 Glutathione reductase, mitochondrial GSR 0.0006
5626 Nucleoside diphosphate kinase B NME2 0.0005
1721 Glycogen synthase kinase-3 beta GSK3B 0.0005
279 Tyrosinase TYR 0.0005
1341 Histamine H3 receptor HRH3 0.0005
3238 Multidrug resistance protein mexA mexA 0.0005
3116 Bacterioferritin bfr 0.0005
4906 Bacterioferritin bfr 0.0005
4965 Bacterioferritin bfr 0.0005
3173 Enolase eno 0.0005
3709 Glycerol uptake facilitator protein glpF 0.0005
3336 C4-dicarboxylate transport transcriptional regulatory protein dctD dctD 0.0005
3393 TGF-beta receptor type-2 TGFBR2 0.0005
5489 Ribonucleoside-diphosphate reductase 1 subunit beta nrdB 0.0005
6743 Non-fluorescent flavoprotein luxF 0.0005
6753 Apolipoprotein M APOM 0.0005
2528 Fatty acid metabolism regulator protein fadR 0.0005
6740 Fatty acid metabolism regulator protein fadR 0.0005
6752 Guanylyl cyclase-activating protein 1 GUCA1A 0.0005
394 Calcineurin subunit B isoform 1 PPP3R1 0.0005
6742 Recoverin RCVRN 0.0005
6747 Chalcone/stilbene synthase family protein MT1417 0.0005
6741 Peroxisomal 3,2-trans-enoyl-CoA isomerase PECI 0.0005
6522 Hepatocyte nuclear factor 4-alpha HNF4A 0.0005
6751 Gag polyprotein gag 0.0005
6746 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform PPP3CA 0.0005
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0005
6749 Polyprotein Not Available 0.0005
3007 Carbonic anhydrase 12 CA12 0.0005
4205 Carbonic anhydrase 9 CA9 0.0005
6344 ATP synthase subunit gamma, mitochondrial ATP5C1 0.0005
6343 ATP synthase subunit beta, mitochondrial ATP5B 0.0005
6342 ATP synthase subunit alpha, mitochondrial ATP5A1 0.0005
2852 DNA mismatch repair protein mutL mutL 0.0005
5961 Insulin INS 0.0005
2236 Casein kinase II subunit alpha CSNK2A1 0.0005
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0005
6527 Lymphocyte antigen 96 LY96 0.0005
3191 Histidinol dehydrogenase hisD 0.0005
5294 Nucleoside diphosphate kinase A NME1 0.0005
6259 (3R)-hydroxymyristoyl-acyl carrier protein dehydratase fabZ 0.0004
6750 ADP-ribosylation factor 6 ARF6 0.0004
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0004
4692 A/G-specific adenine glycosylase mutY 0.0004
6524 Protein tonB tonB 0.0004
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0004
4943 Cytochrome c6 petJ 0.0004
4954 Soluble cytochrome b558 Not Available 0.0004
4942 Diheme cytochrome c napB napB 0.0004
4916 Cyanoglobin glbN 0.0004
4994 Hemoglobin-like protein HbO glbO 0.0004
5000 HemO hemO 0.0004
4981 Iron-starvation protein PigA pigA 0.0004
4984 Neuroglobin NGB 0.0004
4947 Bacterial hemoglobin vhb 0.0004
4935 Cytochrome c-554 cycA1 0.0004
4975 Cytochrome c-556 RPA3973 0.0004
4936 Cytochrome c2 iso-2 Not Available 0.0004
4934 Cytochrome c-551 nirM 0.0004
5218 Cytochrome c-551 nirM 0.0004
4905 Cytochrome c2 Not Available 0.0004
4939 Cytochrome c2 cycA 0.0004
4964 Cytochrome c2 cycA 0.0004
4979 Cytochrome c2 cycA 0.0004
6673 Cytochrome c2 cycA 0.0004
4910 Cytoglobin CYGB 0.0004
4915 Cytochrome c-550 psbV 0.0004
4959 Cytochrome c-550 psbV 0.0004
5216 Cytochrome c-550 psbV 0.0004
4925 Cytochrome c-type protein SHP shp 0.0004
4961 Hemophore HasA hasA 0.0004
4909 CooA protein cooA 0.0004
4998 Hemoglobin-like protein yjbI yjbI 0.0004
4904 Cytochrome c family protein GSU1996 0.0004
4931 Cytochrome P450 167A1 CYP167A1 0.0004
4937 Cytochrome oxidase subunit II rcoxA 0.0004
4903 Methyl-accepting chemotaxis protein Tar4 0.0004
4971 Nonaheme cytochrome c hmcA 0.0004
4989 Cytochrome c551 peroxidase ccp 0.0004
5222 Cytochrome c551 peroxidase ccpA 0.0004
4976 Apocytochrome f petA 0.0004
6407 Apocytochrome f petA 0.0004
4907 Cytochrome c-L moxG 0.0004
6865 Cytochrome c-L moxG 0.0004
4972 P450cin cinA 0.0004
4960 Putative cytochrome P450-family protein SCO7417 0.0004
4764 Cytochrome P450 165C4 CYP165C4 0.0004
4926 Heme-based aerotactic transducer hemAT hemAT 0.0004
4999 Cytochrome P450 165B3 CYP165B3 0.0004
4952 Catalase/peroxidase katA 0.0004
4993 Hydroxylamine oxidoreductase hao1 0.0004
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0004
4922 Cytochrome c, putative SO_4144 0.0004
3093 Catalase HPII katE 0.0004
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0004
2435 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0004
6613 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0004
6163 Copper-transporting ATPase 2 ATP7B 0.0004
6165 Copper-transporting ATPase 1 ATP7A 0.0004
2802 Endoglucanase G celCCG 0.0004
340 Apoptotic protease-activating factor 1 APAF1 0.0004
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0004
719 Retinoic acid receptor responder protein 1 RARRES1 0.0003
770 Retinoic acid-induced protein 3 GPRC5A 0.0003
864 Gag-Pol polyprotein gag-pol 0.0003
2237 Gag-Pol polyprotein gag-pol 0.0003
2326 Gag-Pol polyprotein gag-pol 0.0003
2451 Gag-Pol polyprotein gag-pol 0.0003
2901 Gag-Pol polyprotein gag-pol 0.0003
3165 Gag-Pol polyprotein gag-pol 0.0003
3722 Gag-Pol polyprotein gag-pol 0.0003
6306 Gag-Pol polyprotein gag-pol 0.0003
6624 Gag-Pol polyprotein gag-pol 0.0003
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0003
268 Adenosine A2b receptor ADORA2B 0.0003
828 Phenylalanine-4-hydroxylase PAH 0.0003
3109 Phenylalanine-4-hydroxylase phhA 0.0003
825 Arsenical pump-driving ATPase ASNA1 0.0003
3435 Arsenical pump-driving ATPase arsA 0.0003
486 Serine/threonine-protein kinase ALS2CR7 CDK15 0.0003
2105 ATP-binding cassette sub-family G member 1 ABCG1 0.0003
377 Beta-adrenergic receptor kinase 1 ADRBK1 0.0003
510 Serine/threonine-protein kinase receptor R3 ACVRL1 0.0003
733 Activin receptor type 1B ACVR1B 0.0003
225 NEDD8-activating enzyme E1 regulatory subunit NAE1 0.0003
745 Anti-Muellerian hormone type-2 receptor AMHR2 0.0003
483 A-Raf proto-oncogene serine/threonine-protein kinase ARAF 0.0003
21 Beta-adrenergic receptor kinase 2 ADRBK2 0.0003
154 AFG3-like protein 2 AFG3L2 0.0003
395 ALK tyrosine kinase receptor Not Available 0.0003
292 Activin receptor type-1 ACVR1 0.0003
849 Activated CDC42 kinase 1 TNK2 0.0003
4920 Peroxidase/catalase katG 0.0003
4948 Cytochrome c-553 Not Available 0.0003
4923 Cytochrome c3 DvMF_2499 0.0003
4945 Cytochrome c3 Not Available 0.0003
4949 Cytochrome c3 DVU_3171 0.0003
4968 Cytochrome c3 cytc3 0.0003
4997 Cytochrome c3 SO_2727 0.0003
5219 Cytochrome c3 cyd 0.0003
2119 Cytochrome b5 CYB5A 0.0003
4902 Nine-heme cytochrome c Ddes_2038 0.0003
3189 High-molecular-weight cytochrome c hmcA 0.0003
4990 PpcA ppcA 0.0003
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0003
2427 Ferrichrome-iron receptor fhuA 0.0003
3375 Acidic cytochrome c3 Not Available 0.0003
4988 Sulfite oxidase, mitochondrial SUOX 0.0003
4037 Hypothetical protein GPX1 0.0003
4297 Hypothetical protein SP_1951 0.0003
4521 Hypothetical protein BC_2969 0.0003
4540 Hypothetical protein TM_1070 0.0003
4555 Hypothetical protein MT1739 0.0003
4569 Hypothetical protein mshD 0.0003
4578 Hypothetical protein PA3270 0.0003
4747 Hypothetical protein PA3967 0.0003
5177 Hypothetical protein TM_0096 0.0003
5194 Hypothetical protein PA1204 0.0003
5240 Hypothetical protein Rv2991 0.0003
5370 Hypothetical protein TM_1158 0.0003
5710 Hypothetical protein Tb927.5.1360 0.0003
3570 Cytochrome P450 152A1 cypC 0.0003
2915 Sensor protein fixL fixL 0.0003
4944 Sensor protein fixL fixL 0.0003
4289 Cytochrome P450 TT_P0059 0.0003
6262 Cytochrome P450 staP 0.0003
4813 Heme oxygenase hmuO 0.0003
5769 Heme oxygenase Not Available 0.0003
4992 Cytochrome c peroxidase Not Available 0.0003
4385 Cytochrome c' Not Available 0.0003
4967 Cytochrome c' cycA 0.0003
5038 Cytochrome c' Not Available 0.0003
5223 Cytochrome c' cycP 0.0003
704 Long-chain-fatty-acid--CoA ligase 1 ACSL1 0.0003
821 Acetyl-coenzyme A synthetase 2-like, mitochondrial ACSS1 0.0003
386 Acetyl-coenzyme A synthetase, cytoplasmic ACSS2 0.0003
297 Adenylate cyclase type 1 ADCY1 0.0003
289 Cytosolic purine 5'-nucleotidase NT5C2 0.0003
2230 Catalase CAT 0.0003
3249 Catalase katA 0.0003
3625 Catalase katA 0.0003
4539 Catalase katA 0.0003
4941 Catalase katB 0.0003
6264 cAMP-dependent protein kinase inhibitor alpha PKIA 0.0003
748 5'-AMP-activated protein kinase catalytic subunit alpha-1 PRKAA1 0.0003
3670 Soluble cytochrome b562 precursor cybC 0.0003
3411 Cytochrome P450 121 cyp121 0.0003
3291 Cytochrome c-552 cycA 0.0003
4927 Cytochrome c-552 nrfA 0.0003
4938 Cytochrome c-552 cycA 0.0003
4953 Cytochrome c-552 nrfA 0.0003
5217 Cytochrome c-552 cycM 0.0003
2617 Nitric oxide synthase oxygenase nos 0.0003
2701 Nitric oxide synthase oxygenase nos 0.0003
3102 Flavohemoprotein hmp 0.0003
4969 Flavohemoprotein hmp 0.0003
4386 Hemoglobin-like protein HbN glbN 0.0003
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0003
740 Argininosuccinate synthase ASS1 0.0002
865 Argininosuccinate synthase ASS1 0.0002
2680 Argininosuccinate synthase argG 0.0002
3194 Argininosuccinate synthase argG 0.0002
661 ADP/ATP translocase 1 SLC25A4 0.0002
6021 Adenosine kinase ADK 0.0002
242 Asparagine synthetase [glutamine-hydrolyzing] ASNS 0.0002
3127 Nitrite reductase nirS 0.0002
3284 Nitrite reductase nirS 0.0002
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0002
2972 6-deoxyerythronolide B hydroxylase eryF 0.0002
358 Cystathionine beta-synthase CBS 0.0002
1507 Cytochrome c CYCS 0.0002
693 Hemoglobin subunit beta HBB 0.0002
6268 Hydroxyacid oxidase 1 HAO1 0.0002
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