DT-Web

DB01424 - Aminophenazone


Identification
Name Aminophenazone
Accession Number DB01424
Type small molecule
Description A pyrazolone with analgesic, anti-inflammatory, and antipyretic properties but has risk of agranulocytosis. A breath test with 13C-labeled aminopyrine has been used as a non-invasive measure of cytochrome P-450 metabolic activity in liver function tests. [PubChem]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 231.2936
Groups approved
Monoisotopic Weight 231.137162181
Pharmacology
Indication Formerly widely used as an antipyretic and analgesic in rheumatism, neuritis, and common colds. Currently used to measure total body water.
Mechanism of action Aminophenazone is metabolized very slowly by normal newborn babies. In older infants, a higher amount of exhaled 13-CO2 is observed.
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Can cause life-threatening agranulocytosis.
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Enzymes


Cytochrome P450 2C19
Name Cytochrome P450 2C19
Gene Name CYP2C19
Actions substrate,inhibitor
References
  • Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. - Pubmed
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.5186
Cytochrome P450 1A2
Name Cytochrome P450 1A2
Gene Name CYP1A2
Actions substrate
References
  • Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. - Pubmed
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.4889
Cytochrome P450 2C8
Name Cytochrome P450 2C8
Gene Name CYP2C8
Actions substrate
References
  • Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. - Pubmed
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.4428
Cytochrome P450 2C9
Name Cytochrome P450 2C9
Gene Name CYP2C9
Actions substrate,inhibitor
References
  • Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. - Pubmed
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.5943
Cytochrome P450 2D6
Name Cytochrome P450 2D6
Gene Name CYP2D6
Actions substrate
References
  • Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. - Pubmed
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.574
Cytochrome P450 3A4
Name Cytochrome P450 3A4
Gene Name CYP3A4
Actions substrate
References
  • Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. - Pubmed
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.7501
Cytochrome P450 2C18
Name Cytochrome P450 2C18
Gene Name CYP2C18
Actions substrate
References
  • Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. - Pubmed
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.2358
Cytochrome P450 17A1
Name Cytochrome P450 17A1
Gene Name CYP17A1
Actions substrate
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.1667
Cytochrome P450 3A7
Name Cytochrome P450 3A7
Gene Name CYP3A7
Actions substrate
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.3085

Transporters


Solute carrier family 22 member 6
Name Solute carrier family 22 member 6
Gene Name SLC22A6
Actions inhibitor
References
  • Apiwattanakul N, Sekine T, Chairoungdua A, Kanai Y, Nakajima N, Sophasan S, Endou H: Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes. Mol Pharmacol. 1999 May;55(5):847-54. - Pubmed
DTHybrid score 0.2987

Predictions


Id Partner name Gene Name Score
4118 Cytochrome P450 3A5 CYP3A5 0.3267
1588 Multidrug resistance protein 1 ABCB1 0.3165
6030 Cytochrome P450 2B6 CYP2B6 0.2276
6013 Cytochrome P450 2E1 CYP2E1 0.1886
6024 Cytochrome P450 1A1 CYP1A1 0.1555
5718 Cytochrome P450 2A6 CYP2A6 0.1445
20 Prostaglandin G/H synthase 1 PTGS1 0.1441
587 Serum albumin ALB 0.144
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.1047
492 Histamine H1 receptor HRH1 0.0878
6142 Solute carrier family 22 member 8 SLC22A8 0.0859
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.085
290 Prostaglandin G/H synthase 2 PTGS2 0.0842
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0824
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0806
862 Multidrug resistance-associated protein 1 ABCC1 0.0803
824 Sodium-dependent serotonin transporter SLC6A4 0.0782
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0772
118 Organic cation/carnitine transporter 2 SLC22A5 0.0705
3811 Cytochrome P450 19A1 CYP19A1 0.0702
831 D(2) dopamine receptor DRD2 0.07
6145 Solute carrier family 22 member 1 SLC22A1 0.066
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0633
1898 Cytochrome P450 1B1 CYP1B1 0.0617
1024 Solute carrier family 22 member 11 SLC22A11 0.0591
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0589
6143 Solute carrier family 22 member 7 SLC22A7 0.0584
502 5-hydroxytryptamine 2A receptor HTR2A 0.0584
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0577
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0574
6144 Solute carrier family 22 member 2 SLC22A2 0.0568
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0563
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0541
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0536
776 Bile salt export pump ABCB11 0.0513
556 Alpha-1A adrenergic receptor ADRA1A 0.0508
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0508
847 Mu-type opioid receptor OPRM1 0.0484
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0482
320 5-hydroxytryptamine 1A receptor HTR1A 0.046
2164 Multidrug resistance-associated protein 4 ABCC4 0.0458
6031 Cytochrome P450 3A43 CYP3A43 0.0431
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0429
766 Beta-2 adrenergic receptor ADRB2 0.0423
468 Cytochrome P450 4A11 CYP4A11 0.0407
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0406
737 Mineralocorticoid receptor NR3C2 0.0402
318 Alpha-2A adrenergic receptor ADRA2A 0.0399
23 D(1A) dopamine receptor DRD1 0.0393
467 Delta-type opioid receptor OPRD1 0.039
713 Sodium-dependent dopamine transporter SLC6A3 0.0386
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0385
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0379
136 Estrogen receptor ESR1 0.0375
590 5-hydroxytryptamine 2C receptor HTR2C 0.0371
94 5-hydroxytryptamine 4 receptor HTR4 0.0369
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0368
146 Androgen receptor AR 0.0365
3941 Amine oxidase [flavin-containing] A MAOA 0.0355
871 Glucocorticoid receptor NR3C1 0.0353
696 Kappa-type opioid receptor OPRK1 0.0348
193 Beta-1 adrenergic receptor ADRB1 0.0348
731 HIV-1 protease HIV-1 protease 0.0345
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0337
756 Sex hormone-binding globulin SHBG 0.0337
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0329
341 5-hydroxytryptamine 3 receptor HTR3A 0.0329
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0327
632 Alpha-1B adrenergic receptor ADRA1B 0.0324
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0323
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0321
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0319
6147 Solute carrier family 22 member 3 SLC22A3 0.0319
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0318
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.0314
404 DNA gyrase subunit A gyrA 0.0314
6224 DNA gyrase subunit A gyrA 0.0314
1050 Bile salt sulfotransferase SULT2A1 0.0309
260 Cytochrome P450 51 ERG11 0.0302
761 Cytochrome P450 51 ERG11 0.0302
3163 Cytochrome P450 51 cyp51 0.0302
833 Organic cation/carnitine transporter 1 SLC22A4 0.03
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0296
817 DNA topoisomerase 2-alpha TOP2A 0.0295
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0288
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0288
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0275
638 D(3) dopamine receptor DRD3 0.0272
465 Calmodulin CALM1 0.0272
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0272
885 5-hydroxytryptamine 1B receptor HTR1B 0.0271
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0262
36 Insulin receptor INSR 0.0258
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0256
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0245
3939 Amine oxidase [flavin-containing] B MAOB 0.0245
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0242
477 DNA topoisomerase 4 subunit A parC 0.0241
886 DNA topoisomerase 4 subunit A parC 0.0241
6226 DNA topoisomerase 4 subunit A parC 0.0241
614 Progesterone receptor PGR 0.024
592 Carbonic anhydrase 4 CA4 0.0238
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0233
295 Carbonic anhydrase 1 CA1 0.0231
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.0229
6141 Sodium/bile acid cotransporter SLC10A1 0.0222
789 Alpha-1D adrenergic receptor ADRA1D 0.0219
725 5-hydroxytryptamine 1D receptor HTR1D 0.0219
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0217
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0216
6182 Cytochrome P450 2J2 CYP2J2 0.0215
629 Alpha-2B adrenergic receptor ADRA2B 0.0215
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0213
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.021
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.021
6148 Multidrug resistance-associated protein 7 ABCC10 0.0207
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0205
3923 Cholinesterase BCHE 0.0204
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0202
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.0198
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0198
122 P2Y purinoceptor 12 P2RY12 0.0197
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0194
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0192
378 Alpha-2C adrenergic receptor ADRA2C 0.0188
432 D(4) dopamine receptor DRD4 0.0188
357 Carbonic anhydrase 2 CA2 0.0187
891 Dihydropteroate synthase folP 0.0187
5359 Dihydropteroate synthase folP 0.0187
7175 Dihydropteroate synthase sulI 0.0187
633 Penicillin-binding proteins 1A/1B pbpA 0.0185
6136 Multidrug resistance-associated protein 5 ABCC5 0.0184
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0184
6102 Arylamine N-acetyltransferase 2 NAT2 0.0182
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0181
70 Type-1 angiotensin II receptor AGTR1 0.0181
738 Monocarboxylate transporter 1 SLC16A1 0.0177
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0176
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0176
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.0175
811 Translocator protein TSPO 0.0175
1757 Myeloperoxidase MPO 0.0173
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0168
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0168
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0168
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0167
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0166
606 Cytochrome P450 27, mitochondrial CYP27A1 0.0166
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0165
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0165
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.0165
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.0165
844 Epidermal growth factor receptor EGFR 0.0164
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0163
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.0162
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0162
84 Nuclear receptor 0B1 NR0B1 0.0157
85 Growth hormone receptor GHR 0.0156
373 Transthyretin TTR 0.0156
504 Mast/stem cell growth factor receptor KIT 0.0151
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0151
436 5-hydroxytryptamine 2B receptor HTR2B 0.0149
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0148
750 Voltage-dependent calcium channel gamma-1 subunit CACNG1 0.0145
6012 Tryptophan 2,3-dioxygenase TDO2 0.0145
80 Peroxisome proliferator-activated receptor alpha PPARA 0.0144
6126 Carbonic anhydrase 7 CA7 0.0141
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0139
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0139
275 Arachidonate 5-lipoxygenase ALOX5 0.0138
6220 Aryl hydrocarbon receptor AHR 0.0136
777 Tumor necrosis factor TNF 0.0135
6014 Cytochrome P450 2A13 CYP2A13 0.0134
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0134
124 Histamine H2 receptor HRH2 0.0134
3639 Thymidine phosphorylase deoA 0.0133
3936 Thymidine phosphorylase TYMP 0.0133
469 Annexin A1 ANXA1 0.0131
723 Cytosolic phospholipase A2 PLA2G4A 0.013
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0128
365 Dihydrofolate reductase DHFR 0.0128
2381 Dihydrofolate reductase DFR1 0.0128
2833 Dihydrofolate reductase Not Available 0.0128
2931 Dihydrofolate reductase folA 0.0128
3544 Dihydrofolate reductase folA 0.0128
3682 Dihydrofolate reductase folA 0.0128
6642 Dihydrofolate reductase folA 0.0128
6756 Dihydrofolate reductase dfrA 0.0128
338 DNA polymerase UL30 0.0128
379 DNA polymerase UL54 0.0128
697 DNA polymerase ORF28 0.0128
2482 DNA polymerase 43 0.0128
4104 DNA polymerase BALF5 0.0128
620 Bifunctional dihydrofolate reductase-thymidylate synthase Not Available 0.0127
716 5-hydroxytryptamine 7 receptor HTR7 0.0127
407 Vascular endothelial growth factor receptor 2 KDR 0.0126
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0125
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0125
163 D(1B) dopamine receptor DRD5 0.0125
4604 Liver carboxylesterase 1 CES1 0.0123
818 50S ribosomal protein L10 rplJ 0.0123
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0123
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0123
308 30S ribosomal protein S12 rpsL 0.0122
6704 30S ribosomal protein S12 rpsL 0.0122
571 Melatonin receptor type 1A MTNR1A 0.0122
362 Melatonin receptor type 1B MTNR1B 0.0122
4148 Serine/threonine-protein kinase mTOR MTOR 0.0122
1010 Cytochrome P450 51A1 CYP51A1 0.0121
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0121
16 Adenosine A1 receptor ADORA1 0.0121
26 Vascular endothelial growth factor receptor 3 FLT4 0.0119
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0117
4120 NADPH--cytochrome P450 reductase POR 0.0117
427 Substance-P receptor TACR1 0.0117
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0116
1178 Adenosine A2a receptor ADORA2A 0.0116
228 Beta platelet-derived growth factor receptor PDGFRB 0.0115
6137 Multidrug resistance-associated protein 6 ABCC6 0.0115
32 Vascular endothelial growth factor receptor 1 FLT1 0.0114
474 Acetylcholinesterase ACHE 0.0113
558 Solute carrier family 12 member 1 SLC12A1 0.0113
1244 Low-density lipoprotein receptor-related protein 2 LRP2 0.0111
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.011
4790 Glycosyltransferase GtfA gtfA 0.011
232 Corticosteroid-binding globulin SERPINA6 0.0109
161 Tubulin beta chain TUBB 0.0109
312 Tubulin beta chain TUB2 0.0109
6174 50S ribosomal protein L32 rpmF 0.0108
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0108
6020 Aldehyde oxidase AOX1 0.0107
645 Penicillin-binding protein 1A mrcA 0.0107
5805 Penicillin-binding protein 1A ponA 0.0107
6185 Penicillin-binding protein 1A mrcA 0.0107
6799 Penicillin-binding protein 1A pbpA 0.0107
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0106
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0106
869 Estrogen receptor beta ESR2 0.0106
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0105
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0104
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0103
1656 CYP2B protein CYP2B 0.0103
1256 5-hydroxytryptamine 6 receptor HTR6 0.0101
3808 Dihydropteroate synthase 2 folP2 0.0101
3601 Dihydropteroate synthase 1 folP1 0.0101
3807 Dihydropteroate synthase 1 folP1 0.0101
3426 Glutamine synthetase glnA 0.01
3987 Glutamine synthetase GLUL 0.01
24 Thymidylate synthase TMP1 0.01
359 Thymidylate synthase TYMS 0.01
2626 Thymidylate synthase thyA 0.01
2729 Thymidylate synthase thyA 0.01
5352 Thymidylate synthase THYA 0.01
29 Tubulin beta-1 chain TUBB1 0.01
140 30S ribosomal protein S9 rpsI 0.01
6719 30S ribosomal protein S9 rpsI 0.01
6725 30S ribosomal protein S9 rpsI 0.01
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0099
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0098
4116 Dihydropteroate synthetase Not Available 0.0097
958 Insulin-like growth factor 1 receptor IGF1R 0.0097
952 Dipeptidyl peptidase 4 DPP4 0.0096
49 Endothelin B receptor EDNRB 0.0096
88 Retinoic acid receptor RXR-beta RXRB 0.0096
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0095
6432 Transporter snf 0.0094
921 Glutamate receptor 2 GRIA2 0.0094
4122 Histone deacetylase 2 HDAC2 0.0094
273 Apoptosis regulator Bcl-2 BCL2 0.0093
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0093
5849 cAMP-dependent protein kinase type I-alpha regulatory subunit PRKAR1A 0.0092
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0092
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0092
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0092
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0092
578 Endothelin-1 receptor EDNRA 0.009
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.009
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0089
3947 Xanthine dehydrogenase/oxidase XDH 0.0089
621 Periplasmic [Fe] hydrogenase 1 Not Available 0.0088
208 DNA-directed RNA polymerase beta' chain rpoC 0.0087
5774 DNA-directed RNA polymerase beta' chain rpoC 0.0087
1196 Complement decay-accelerating factor CD55 0.0086
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0085
528 5-hydroxytryptamine 1E receptor HTR1E 0.0085
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0083
3806 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A 0.0083
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.0083
6085 Fatty acid-binding protein, intestinal FABP2 0.0083
183 Vascular endothelial growth factor A VEGFA 0.0082
2016 Dipeptidase 1 DPEP1 0.0082
780 Retinoic acid receptor RXR-gamma RXRG 0.0082
7 Nitric oxide synthase, inducible NOS2 0.0082
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0081
2320 Thymidine kinase, cytosolic TK1 0.0081
22 30S ribosomal protein S4 rpsD 0.0081
6714 30S ribosomal protein S4 rpsD 0.0081
565 Extracellular calcium-sensing receptor CASR 0.008
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.008
3810 Catechol O-methyltransferase COMT 0.008
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.008
173 Toll-like receptor 7 TLR7 0.0079
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0078
442 Envelope glycoprotein gp41 0.0078
4859 Envelope glycoprotein env 0.0078
6043 Putative G-protein coupled receptor 44 GPR44 0.0077
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0077
543 Penicillin-binding protein 1B mrcB 0.0077
6186 Penicillin-binding protein 1B ponB 0.0077
6822 Penicillin-binding protein 1b pbp1b 0.0077
6844 Penicillin-binding protein 1b pbp1b 0.0077
518 Peroxidase/catalase T katG 0.0075
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.0075
2808 Chloramphenicol acetyltransferase 3 cat3 0.0074
814 Ryanodine receptor 1 RYR1 0.0074
1541 Metalloproteinase mmp20 0.0074
3932 Glutathione S-transferase A2 GSTA2 0.0074
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0073
5626 Nucleoside diphosphate kinase B NME2 0.0073
2183 Fatty acid-binding protein, adipocyte FABP4 0.0072
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0072
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0071
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0071
4203 Histamine N-methyltransferase HNMT 0.0071
2539 Tubulin alpha-1 chain TUBA4A 0.007
162 Retinoic acid receptor gamma-1 RARG 0.007
130 Prostacyclin synthase PTGIS 0.0069
634 Squalene monooxygenase SQLE 0.0069
7196 Squalene monooxygenase ERG1 0.0069
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0068
2417 Chloramphenicol acetyltransferase cat 0.0068
3278 Chloramphenicol acetyltransferase cat 0.0068
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0068
6044 Serum paraoxonase/lactonase 3 PON3 0.0068
1629 Transcription factor AP-1 JUN 0.0068
2112 Toll-like receptor 9 TLR9 0.0068
1192 Sulfotransferase 1A1 SULT1A1 0.0067
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0067
569 Retinal dehydrogenase 2 ALDH1A2 0.0067
284 DNA-directed RNA polymerase beta chain rpoB 0.0067
5773 DNA-directed RNA polymerase beta chain rpoB 0.0067
2810 Dr hemagglutinin structural subunit draA 0.0067
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0067
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0067
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0066
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0066
527 Prostacyclin receptor PTGIR 0.0066
1517 Beta-3 adrenergic receptor ADRB3 0.0066
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0066
596 3-oxo-5-alpha-steroid 4-dehydrogenase 1 SRD5A1 0.0065
3917 Methylenetetrahydrofolate reductase MTHFR 0.0065
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0065
1275 Estrogen sulfotransferase SULT1E1 0.0065
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0065
4237 50S ribosomal protein L22 rplV 0.0064
1618 High affinity nerve growth factor receptor NTRK1 0.0064
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0064
4773 Deoxycytidine kinase DCK 0.0064
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0064
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.0064
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.0064
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0064
719 Retinoic acid receptor responder protein 1 RARRES1 0.0064
770 Retinoic acid-induced protein 3 GPRC5A 0.0064
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.0064
611 Retinal dehydrogenase 1 ALDH1A1 0.0063
6068 Guanylate cyclase soluble subunit alpha-2 GUCY1A2 0.0063
1648 Elastin ELN 0.0063
165 FL cytokine receptor FLT3 0.0063
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0063
133 Dihydropterate synthase sulI 0.0063
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0062
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0062
6149 Solute carrier family 22 member 10 SLC22A10 0.0062
990 Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 0.0062
482 Glycine receptor subunit alpha-1 GLRA1 0.0062
511 5-hydroxytryptamine 1F receptor HTR1F 0.0061
856 Vitamin D3 receptor VDR 0.006
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.006
1039 Histone deacetylase 9 HDAC9 0.006
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.006
564 Cellular retinoic acid-binding protein 1 CRABP1 0.006
2981 Phospholipase A2, membrane associated PLA2G2A 0.006
5251 Carbonyl reductase [NADPH] 1 CBR1 0.006
276 Sodium- and chloride-dependent GABA transporter 1 SLC6A1 0.006
131 Synaptic vesicular amine transporter SLC18A2 0.0059
823 Fibroblast growth factor receptor 2 FGFR2 0.0059
5294 Nucleoside diphosphate kinase A NME1 0.0058
68 Cannabinoid receptor 1 CNR1 0.0058
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.0058
4311 tRNA TRDMT1 0.0058
4325 tRNA trmD 0.0058
4328 tRNA trmD 0.0058
5880 Thrombopoietin receptor MPL 0.0058
174 Sigma 1-type opioid receptor SIGMAR1 0.0058
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0057
768 FK506-binding protein 1A FKBP1A 0.0057
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0057
976 Platelet glycoprotein IX GP9 0.0057
1483 Membrane copper amine oxidase AOC3 0.0057
459 Retinoic acid receptor RXR-alpha RXRA 0.0057
65 Matrix metalloproteinase-9 Not Available 0.0056
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0056
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0056
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0055
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0055
642 3-oxo-5-alpha-steroid 4-dehydrogenase 2 SRD5A2 0.0055
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.0055
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.0055
6506 Stathmin-4 STMN4 0.0055
5300 Antigen peptide transporter 1 TAP1 0.0055
466 Solute carrier family 12 member 3 SLC12A3 0.0055
3937 Fatty-acid amide hydrolase FAAH 0.0054
5998 Toll-like receptor 8 TLR8 0.0053
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0053
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.0053
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0052
712 Tubulin alpha chain TUB1 0.0052
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0052
319 Opioid receptor, sigma 1 OPRS1 0.0052
259 Microsomal triglyceride transfer protein large subunit MTTP 0.0052
714 Glutathione reductase, mitochondrial GSR 0.0052
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0051
438 Taste receptor type 1 member 2 TAS1R2 0.0051
253 Sodium/potassium-transporting ATPase gamma chain FXYD2 0.0051
581 Cytochrome P450 2R1 CYP2R1 0.005
4199 Sphingosine 1-phosphate receptor Edg-8 S1PR5 0.005
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.005
613 Atrial natriuretic peptide receptor A NPR1 0.005
4238 50S ribosomal protein L4 rplD 0.0049
5578 50S ribosomal protein L4 rplD 0.0049
6173 50S ribosomal protein L4 rplD 0.0049
6219 50S ribosomal protein L4 rplD 0.0049
1630 Integrin beta-2 ITGB2 0.0049
1852 Microtubule-associated protein 2 MAP2 0.0049
244 Angiotensin-converting enzyme ACE 0.0049
6146 High affinity copper uptake protein 1 SLC31A1 0.0049
277 Purine nucleoside phosphorylase PNP 0.0049
2870 Purine nucleoside phosphorylase punA 0.0049
2945 Purine nucleoside phosphorylase punA 0.0049
4659 Purine nucleoside phosphorylase TM_1596 0.0049
4825 Purine nucleoside phosphorylase TTHA1435 0.0049
563 Thyroid peroxidase TPO 0.0048
6131 Carbonic anhydrase 14 CA14 0.0048
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0048
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0048
215 Sodium channel protein type 11 subunit alpha SCN11A 0.0048
6033 High affinity interleukin-8 receptor A CXCR1 0.0046
4228 Keratin, type II cytoskeletal 7 KRT7 0.0046
3686 Acyl-CoA thioesterase I precursor tesA 0.0045
992 Protein tyrosine kinase 2 beta PTK2B 0.0045
3086 Plasmepsin-2 Not Available 0.0045
3856 Fibroblast growth factor receptor 3 FGFR3 0.0045
6122 Carbonic anhydrase 3 CA3 0.0045
239 Coagulation factor X F10 0.0045
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0045
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0045
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0045
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0045
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0045
904 Glutathione S-transferase P GSTP1 0.0045
6339 Ig kappa chain V-II region RPMI 6410 Not Available 0.0044
153 Dopamine beta-hydroxylase DBH 0.0044
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.0043
1360 Sphingomyelin phosphodiesterase SMPD1 0.0043
4103 Proteasome subunit beta type 2 PSMB2 0.0043
4102 Proteasome subunit beta type 5 PSMB5 0.0043
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0043
4101 Proteasome subunit beta type 1 PSMB1 0.0043
705 Glutamate receptor 1 GRIA1 0.0043
3809 Estrogen-related receptor gamma ESRRG 0.0043
5698 Riboflavin synthase alpha chain ribE 0.0043
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.0042
5923 Microtubule-associated protein tau MAPT 0.0042
5924 Microtubule-associated protein 4 MAP4 0.0042
4217 Telomerase reverse transcriptase TERT 0.0042
115 Penicillin-binding protein 2 mrdA 0.0041
6069 Penicillin-binding protein 2 mrdA 0.0041
6118 Penicillin-binding protein 2 penA 0.0041
6187 Penicillin-binding protein 2 pbpA 0.0041
6686 Penicillin-binding protein 2 pbp2 0.0041
6939 Penicillin-binding protein 2 mrdA 0.0041
7163 Penicillin-binding protein 2 pbpA 0.0041
887 DNA gyrase subunit B gyrB 0.0041
4150 DNA gyrase subunit B gyrB 0.0041
6225 DNA gyrase subunit B gyrB 0.0041
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0041
408 Riboflavin kinase RFK 0.0041
2449 Tubulin alpha-3 chain TUBA1A 0.0041
3997 Cytochrome P450 24A1, mitochondrial CYP24A1 0.0041
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.004
3913 Glutamic acid decarboxylase GAD65 0.004
654 Flavin reductase BLVRB 0.004
33 Cystine/glutamate transporter SLC7A11 0.004
6032 PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) fas 0.004
1558 Transient receptor potential cation channel subfamily V member 1 TRPV1 0.004
54 Prothrombin F2 0.004
2268 Cholesterol oxidase choB 0.0039
2822 Cholesterol oxidase choA 0.0039
6138 Multidrug resistance protein 3 ABCB4 0.0039
6105 3-oxo-5-beta-steroid 4-dehydrogenase AKR1D1 0.0039
360 Ribonucleoside-diphosphate reductase large subunit RRM1 0.0039
164 Histamine H4 receptor HRH4 0.0039
1129 C-C chemokine receptor type 5 CCR5 0.0039
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0039
1 Peptidoglycan synthetase ftsI ftsI 0.0038
4155 Peptidoglycan synthetase ftsI ftsI 0.0038
4209 ATP-sensitive inward rectifier potassium channel 8 KCNJ8 0.0038
605 Fumarate reductase flavoprotein subunit frdA 0.0038
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0038
3673 Fumarate reductase flavoprotein subunit fccA 0.0038
4912 Fumarate reductase flavoprotein subunit ifcA 0.0038
6549 Fumarate reductase flavoprotein subunit frdA 0.0038
1992 Vitamin D-binding protein GC 0.0038
3957 Adenosine deaminase ADA 0.0038
5934 Cytochrome P450 26A1 CYP26A1 0.0038
3007 Carbonic anhydrase 12 CA12 0.0038
4205 Carbonic anhydrase 9 CA9 0.0038
6169 ATP-binding cassette sub-family A member 5 ABCA5 0.0037
5353 Glutamate decarboxylase alpha gadA 0.0037
6103 Arylamine N-acetyltransferase 1 NAT1 0.0037
572 Integrin alpha-L ITGAL 0.0037
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0037
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0037
2283 Steroid Delta-isomerase ksi 0.0037
2920 Steroid Delta-isomerase ksi 0.0037
6167 Organic solute transporter subunit beta OSTB 0.0037
6166 Organic solute transporter subunit alpha OSTA 0.0037
5787 Angiopoietin-1 receptor TEK 0.0036
1867 Major prion protein PRNP 0.0036
707 72 kDa type IV collagenase MMP2 0.0036
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0036
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0036
185 Vasopressin V1a receptor AVPR1A 0.0035
251 Alcohol dehydrogenase 1A ADH1A 0.0035
6048 Troponin C, skeletal muscle TNNC2 0.0035
117 Sterol O-acyltransferase 1 SOAT1 0.0035
241 Calcium-transporting ATPase type 2C member 1 ATP2C1 0.0035
889 3-oxoacyl-[acyl-carrier-protein] synthase 1 fabB 0.0035
6860 3-oxoacyl-[acyl-carrier-protein] synthase 1 kasA 0.0035
1025 Aquaporin-1 AQP1 0.0035
939 50S ribosomal protein L3 rplC 0.0035
1864 RET proto-oncogene RET 0.0034
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0034
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0034
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0034
322 Vasopressin V2 receptor AVPR2 0.0034
1714 Mitogen-activated protein kinase 3 MAPK3 0.0034
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0034
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0034
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0034
2325 Sulfotransferase family cytosolic 2B member 1 SULT2B1 0.0034
2499 Tubulin beta-2C chain TUBB2C 0.0034
3904 Alanine aminotransferase 2 GPT2 0.0034
735 Alanine aminotransferase 1 GPT 0.0034
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0033
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0033
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0033
229 Retinoic acid receptor beta RARB 0.0033
537 ATP synthase delta chain, mitochondrial ATP5D 0.0033
332 Beta-lactamase blaZ 0.0033
2478 Beta-lactamase ampC 0.0033
2613 Beta-lactamase ampC 0.0033
2635 Beta-lactamase ampC 0.0033
2700 Beta-lactamase penP 0.0033
5445 Beta-lactamase blaB 0.0033
6019 Beta-lactamase SHV-7 0.0033
6701 Beta-lactamase cphA 0.0033
730 Retinoic acid receptor alpha RARA 0.0032
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0032
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0032
267 Plasminogen activator inhibitor 1 SERPINE1 0.0032
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.0032
444 Alcohol dehydrogenase 1B ADH1B 0.0032
2021 Thrombomodulin THBD 0.0032
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0032
473 L-lactate dehydrogenase A chain LDHA 0.0031
751 Potassium channel subfamily K member 6 KCNK6 0.0031
1636 Trace amine-associated receptor 1 TAAR1 0.0031
6207 30S ribosomal protein S14 rpsN 0.0031
6209 30S ribosomal protein S19 rpsS 0.0031
6712 30S ribosomal protein S19 rpsS 0.0031
6726 30S ribosomal protein S19 rpsS 0.0031
1227 Cytochrome b MT-CYB 0.0031
6386 Cytochrome b petB 0.0031
6937 Cytochrome b MT-CYB 0.0031
674 Dihydroorotate dehydrogenase homolog, mitochondrial PFF0160c 0.0031
342 P protein [Includes: DNA-directed DNA polymerase P 0.0031
612 P protein [Includes: DNA-directed DNA polymerase P 0.0031
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.0031
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.0031
2578 Tubulin beta-3 chain TUBB3 0.003
106 Cannabinoid receptor 2 CNR2 0.003
2285 Streptogramin A acetyltransferase vatD 0.003
741 Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 0.003
822 Aldose reductase AKR1B1 0.0029
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0029
6218 Pannexin-1 PANX1 0.0029
268 Adenosine A2b receptor ADORA2B 0.0029
172 Potassium channel subfamily K member 1 KCNK1 0.0029
512 DNA-directed RNA polymerase alpha chain rpoA 0.0029
5772 DNA-directed RNA polymerase alpha chain rpoA 0.0029
3688 Branched-chain-amino-acid aminotransferase ilvE 0.0028
4252 Penicillin-binding protein 5 dacA 0.0028
6221 Steroid hormone receptor ERR1 ESRRA 0.0028
102 DNA topoisomerase I, mitochondrial TOP1MT 0.0028
159 Penicillin-binding protein 2B penA 0.0028
6121 Penicillin-binding protein 2B penA 0.0028
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0028
1200 AMBP protein AMBP 0.0028
3866 Serum amyloid A protein SAA1 0.0028
1932 Apolipoprotein E APOE 0.0028
517 Alcohol dehydrogenase 1C ADH1C 0.0027
1144 Hepatocyte growth factor receptor MET 0.0027
4173 Tyrosine-protein kinase JAK2 JAK2 0.0027
2159 Quinone oxidoreductase CRYZ 0.0027
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0027
3849 Insulin-like growth factor-binding protein 7 IGFBP7 0.0027
2009 Protein NOV homolog NOV 0.0027
3847 Neuroendocrine convertase 2 PCSK2 0.0027
1949 Carboxypeptidase E CPE 0.0027
3850 Synaptotagmin-like protein 4 SYTL4 0.0027
3848 Neuroendocrine convertase 1 PCSK1 0.0027
3846 Retinoblastoma-associated protein RB1 0.0027
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0027
3685 Catabolite gene activator crp 0.0027
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0027
4655 Adenylate cyclase cyaC 0.0027
4759 Adenylate cyclase cyaB2 0.0027
1262 Corticotropin-lipotropin POMC 0.0027
936 Ephrin type-A receptor 2 EPHA2 0.0026
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0026
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.0026
790 DNA polymerase subunit alpha B POLA2 0.0026
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0026
293 Gamma-glutamyl hydrolase GGH 0.0026
1507 Cytochrome c CYCS 0.0026
509 Thymidine kinase TK 0.0025
570 Thymidine kinase TK 0.0025
2559 Thymidine kinase TK 0.0025
3430 Thymidine kinase tdk 0.0025
3518 Thymidine kinase TK 0.0025
5301 Thymidine kinase tdk 0.0025
5771 Thymidine kinase ORF36 0.0025
7009 Thymidine kinase ORF36 0.0025
3830 Calreticulin CALR 0.0025
390 Adenosine A3 receptor ADORA3 0.0025
1374 Natriuretic peptides B NPPB 0.0025
1827 Gap junction alpha-1 protein GJA1 0.0025
1908 Vascular cell adhesion protein 1 VCAM1 0.0025
544 Potassium voltage-gated channel subfamily E member 1 KCNE1 0.0024
2300 Lysozyme E 0.0024
3633 Lysozyme R 0.0024
5597 Lysozyme 17 0.0024
5878 Alpha-7 nicotinic cholinergic receptor subunit CHRFAM7A 0.0024
489 Monocarboxylate transporter 2 SLC16A7 0.0024
6039 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A PDE11A 0.0024
471 Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) SLC6A14 0.0024
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0024
6070 Nischarin NISCH 0.0024
233 Potassium channel subfamily K member 2 KCNK2 0.0024
5852 Type-2 angiotensin II receptor AGTR2 0.0024
6100 BDNF/NT-3 growth factors receptor NTRK2 0.0024
1525 Heparin-binding growth factor 2 FGF2 0.0023
4226 Uridine phosphorylase 2 UPP2 0.0023
6034 Hydroxyindole O-methyltransferase ASMT 0.0023
6035 Nuclear receptor ROR-beta RORB 0.0023
6036 Eosinophil peroxidase EPX 0.0023
4192 DNA topoisomerase 2-beta TOP2B 0.0023
550 Amiloride-sensitive sodium channel subunit delta SCNN1D 0.0023
27 Amiloride-sensitive sodium channel subunit beta SCNN1B 0.0023
552 Amiloride-sensitive sodium channel subunit gamma SCNN1G 0.0023
213 Amiloride-sensitive sodium channel subunit alpha SCNN1A 0.0023
1830 5'-nucleotidase NT5E 0.0023
2249 Aspartate aminotransferase aspC 0.0023
2671 Aspartate aminotransferase aspC 0.0023
5490 Aspartate aminotransferase Not Available 0.0023
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0023
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0023
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0023
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0023
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0023
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0023
1341 Histamine H3 receptor HRH3 0.0023
1353 DNA topoisomerase 1 TOP1 0.0023
3552 DNA topoisomerase 1 topA 0.0023
1650 Heme carrier protein 1 SLC46A1 0.0023
820 Glycine receptor subunit alpha-2 GLRA2 0.0023
4760 Mll3241 protein mll3241 0.0023
908 Glutathione S-transferase theta-1 GSTT1 0.0023
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0022
5798 Mitogen-activated protein kinase 11 MAPK11 0.0022
3404 Exotoxin A eta 0.0022
1792 Tissue-type plasminogen activator PLAT 0.0022
2155 Insulin-degrading enzyme IDE 0.0022
2232 Interleukin-5 IL5 0.0022
6824 Tyrosine-protein kinase Lyn LYN 0.0021
298 Renin REN 0.0021
1593 Mucin-2 MUC2 0.0021
4225 Uridine phosphorylase 1 UPP1 0.0021
1638 Solute carrier family 2, facilitated glucose transporter member 2 SLC2A2 0.0021
2091 Endoplasmin HSP90B1 0.0021
718 Folate receptor gamma FOLR3 0.0021
299 Folate receptor beta FOLR2 0.0021
804 Mitochondrial folate transporter/carrier SLC25A32 0.0021
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0021
1198 Serum paraoxonase/arylesterase 1 PON1 0.0021
6223 Penicillin-binding protein 1C pbpC 0.0021
63 Malate dehydrogenase mdh 0.0021
2329 Malate dehydrogenase mdh 0.0021
3445 Malate dehydrogenase mdh 0.0021
4420 Malate dehydrogenase mdh 0.0021
4438 Malate dehydrogenase mdh 0.0021
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0021
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0021
828 Phenylalanine-4-hydroxylase PAH 0.0021
3109 Phenylalanine-4-hydroxylase phhA 0.0021
132 ATP-binding cassette sub-family A member 1 ABCA1 0.002
594 Thyroxine-binding globulin SERPINA7 0.002
765 Indoleamine 2,3-dioxygenase IDO1 0.002
672 Prostaglandin F2-alpha receptor PTGFR 0.002
3090 Chitosanase csn 0.002
4149 Nuclear factor NF-kappa-B p100 subunit NFKB2 0.002
3611 Cytidine deaminase cdd 0.002
3707 Cytidine deaminase cdd 0.002
4211 Cytidine deaminase CDA 0.002
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.002
413 Amidophosphoribosyltransferase PPAT 0.002
2515 Amidophosphoribosyltransferase purF 0.002
3714 Amidophosphoribosyltransferase purF 0.002
2236 Casein kinase II subunit alpha CSNK2A1 0.002
1820 Beta-nerve growth factor NGF 0.002
2216 Fibroblast growth factor receptor 4 FGFR4 0.0019
867 Penicillin-binding protein 3 pbpC 0.0019
6119 Penicillin-binding protein 3 pbp3 0.0019
7154 Penicillin-binding protein 3 pbp3 0.0019
7157 Penicillin-binding protein 3 LMHCC_2184 0.0019
7162 Penicillin-binding protein 3 pbpB 0.0019
7172 Penicillin-binding protein 3 pbp3 0.0019
291 Nitric-oxide synthase, endothelial NOS3 0.0019
1291 cAMP response element-binding protein CREB1 0.0019
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0019
760 Fibroblast growth factor 1 FGF1 0.0019
1654 Interleukin-1 beta IL1B 0.0019
758 Thyroid hormone receptor alpha THRA 0.0019
893 [Citrate [pro-3S]-lyase] ligase citC 0.0018
845 Pyruvate dehydrogenase [cytochrome] poxB 0.0018
1253 Interferon gamma IFNG 0.0018
4210 Toll-like receptor 4 TLR4 0.0018
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0018
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0018
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0018
6766 O-GlcNAcase BT_4395 BT_4395 0.0018
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0018
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0018
1968 ATP-sensitive inward rectifier potassium channel 12 KCNJ12 0.0018
327 Glutathione reductase gor 0.0018
5110 Glutathione reductase GR2 0.0018
683 Potassium transporter GK0582 0.0018
748 5'-AMP-activated protein kinase catalytic subunit alpha-1 PRKAA1 0.0018
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0018
53 Solute carrier family 12 member 5 SLC12A5 0.0018
663 Solute carrier family 12 member 4 SLC12A4 0.0018
1123 Eosinophil cationic protein RNASE3 0.0018
199 Monocarboxylate transporter 8 SLC16A2 0.0018
67 Prolyl 4-hydroxylase subunit alpha-1 P4HA1 0.0017
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0017
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0017
2290 ADP-ribosyl cyclase 2 BST1 0.0017
6042 Prostaglandin reductase 2 PTGR2 0.0017
810 Heme oxygenase 1 HMOX1 0.0017
3391 Heme oxygenase 1 pbsA1 0.0017
4948 Cytochrome c-553 Not Available 0.0017
310 Solute carrier family 12 member 2 SLC12A2 0.0017
4923 Cytochrome c3 DvMF_2499 0.0017
4945 Cytochrome c3 Not Available 0.0017
4949 Cytochrome c3 DVU_3171 0.0017
4968 Cytochrome c3 cytc3 0.0017
4997 Cytochrome c3 SO_2727 0.0017
5219 Cytochrome c3 cyd 0.0017
4902 Nine-heme cytochrome c Ddes_2038 0.0017
3189 High-molecular-weight cytochrome c hmcA 0.0017
346 Thyroid hormone receptor beta-1 THRB 0.0017
144 Hemoglobin subunit alpha HBA1 0.0016
1243 Cathepsin D CTSD 0.0016
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0016
816 Biliverdin reductase A BLVRA 0.0016
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0016
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0016
2207 Rhodopsin RHO 0.0016
3233 Bile acid receptor NR1H4 0.0015
2853 14 kDa fatty acid-binding protein Not Available 0.0015
494 Caspase-1 CASP1 0.0015
896 Glutathione S-transferase Mu 1 GSTM1 0.0015
3126 Poly [ADP-ribose] polymerase 1 PARP1 0.0015
982 Cocaine- and amphetamine-regulated transcript protein CARTPT 0.0015
3844 HLA class II histocompatibility antigen, DQ(6) alpha chain HLA-DQA2 0.0015
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0015
1405 Thiopurine S-methyltransferase TPMT 0.0015
4954 Soluble cytochrome b558 Not Available 0.0014
4934 Cytochrome c-551 nirM 0.0014
5218 Cytochrome c-551 nirM 0.0014
4905 Cytochrome c2 Not Available 0.0014
4939 Cytochrome c2 cycA 0.0014
4964 Cytochrome c2 cycA 0.0014
4979 Cytochrome c2 cycA 0.0014
6673 Cytochrome c2 cycA 0.0014
4915 Cytochrome c-550 psbV 0.0014
4959 Cytochrome c-550 psbV 0.0014
5216 Cytochrome c-550 psbV 0.0014
4925 Cytochrome c-type protein SHP shp 0.0014
4947 Bacterial hemoglobin vhb 0.0014
4998 Hemoglobin-like protein yjbI yjbI 0.0014
4975 Cytochrome c-556 RPA3973 0.0014
4943 Cytochrome c6 petJ 0.0014
4916 Cyanoglobin glbN 0.0014
4984 Neuroglobin NGB 0.0014
4936 Cytochrome c2 iso-2 Not Available 0.0014
3116 Bacterioferritin bfr 0.0014
4906 Bacterioferritin bfr 0.0014
4965 Bacterioferritin bfr 0.0014
4994 Hemoglobin-like protein HbO glbO 0.0014
4907 Cytochrome c-L moxG 0.0014
6865 Cytochrome c-L moxG 0.0014
4909 CooA protein cooA 0.0014
755 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NDUFA3 0.0014
4942 Diheme cytochrome c napB napB 0.0014
4935 Cytochrome c-554 cycA1 0.0014
4904 Cytochrome c family protein GSU1996 0.0014
4910 Cytoglobin CYGB 0.0014
4961 Hemophore HasA hasA 0.0014
4971 Nonaheme cytochrome c hmcA 0.0014
4981 Iron-starvation protein PigA pigA 0.0014
5000 HemO hemO 0.0014
4989 Cytochrome c551 peroxidase ccp 0.0014
5222 Cytochrome c551 peroxidase ccpA 0.0014
4976 Apocytochrome f petA 0.0014
6407 Apocytochrome f petA 0.0014
300 NADH-ubiquinone oxidoreductase chain 4L MT-ND4L 0.0014
374 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NDUFB1 0.0014
4999 Cytochrome P450 165B3 CYP165B3 0.0014
4764 Cytochrome P450 165C4 CYP165C4 0.0014
4960 Putative cytochrome P450-family protein SCO7417 0.0014
4931 Cytochrome P450 167A1 CYP167A1 0.0014
99 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NDUFS5 0.0014
4926 Heme-based aerotactic transducer hemAT hemAT 0.0014
4937 Cytochrome oxidase subunit II rcoxA 0.0014
446 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NDUFA7 0.0014
219 NADH-ubiquinone oxidoreductase chain 3 MT-ND3 0.0014
4993 Hydroxylamine oxidoreductase hao1 0.0014
4903 Methyl-accepting chemotaxis protein Tar4 0.0014
4922 Cytochrome c, putative SO_4144 0.0014
4972 P450cin cinA 0.0014
104 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NDUFS6 0.0014
247 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUFA1 0.0014
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0014
3093 Catalase HPII katE 0.0014
236 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NDUFA6 0.0014
324 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NDUFB4 0.0014
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0014
4952 Catalase/peroxidase katA 0.0014
343 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NDUFC1 0.0014
568 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NDUFB7 0.0014
30 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NDUFV3 0.0014
582 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NDUFA13 0.0014
190 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 NDUFA4 0.0014
353 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 NDUFA4L2 0.0014
525 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NDUFA5 0.0014
602 Acyl carrier protein, mitochondrial NDUFAB1 0.0014
417 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NDUFB6 0.0014
313 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NDUFB3 0.0014
384 NADH-ubiquinone oxidoreductase chain 6 MT-ND6 0.0014
607 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NDUFA2 0.0014
555 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 0.0014
598 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NDUFA11 0.0014
656 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 0.0014
746 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NDUFB8 0.0014
475 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NDUFB2 0.0014
270 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NDUFB5 0.0014
372 Estradiol 17-beta-dehydrogenase 3 HSD17B3 0.0014
608 NADH-ubiquinone oxidoreductase chain 4 MT-ND4 0.0014
141 3-hydroxyisobutyrate dehydrogenase, mitochondrial HIBADH 0.0014
405 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NDUFA8 0.0014
721 NADH-ubiquinone oxidoreductase chain 2 MT-ND2 0.0014
216 Aldehyde dehydrogenase 3B2 ALDH3B2 0.0014
616 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial IDH3B 0.0014
152 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NDUFV2 0.0014
829 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NDUFA12 0.0014
609 15-hydroxyprostaglandin dehydrogenase [NAD+] HPGD 0.0014
41 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NDUFS8 0.0014
272 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NDUFB10 0.0014
662 Fatty aldehyde dehydrogenase ALDH3A2 0.0014
644 Heme oxygenase 2 HMOX2 0.0014
4982 Heme oxygenase 2 pbsA2 0.0014
167 L-lactate dehydrogenase C chain LDHC 0.0014
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.0014
3726 D-3-phosphoglycerate dehydrogenase serA 0.0014
4291 D-3-phosphoglycerate dehydrogenase serA 0.0014
196 D-beta-hydroxybutyrate dehydrogenase, mitochondrial BDH1 0.0014
231 Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic GPD1 0.0014
91 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NDUFA10 0.0014
14 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial IDH3A 0.0014
50 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating NSDHL 0.0014
335 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NDUFA9 0.0014
112 L-lactate dehydrogenase A-like 6B LDHAL6B 0.0014
9 Estradiol 17-beta-dehydrogenase 2 HSD17B2 0.0014
628 Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial PDHA1 0.0014
848 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial IDH3G 0.0014
145 Corticosteroid 11-beta-dehydrogenase isozyme 2 HSD11B2 0.0014
729 GDP-L-fucose synthetase TSTA3 0.0014
3463 GDP-L-fucose synthetase fcl 0.0014
326 L-lactate dehydrogenase A-like 6A LDHAL6A 0.0014
539 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NDUFV1 0.0014
496 Aldehyde dehydrogenase 3B1 ALDH3B1 0.0014
34 7-dehydrocholesterol reductase DHCR7 0.0014
711 UDP-glucose 6-dehydrogenase UGDH 0.0014
3672 UDP-glucose 6-dehydrogenase hasB 0.0014
393 GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase H6PD 0.0014
149 Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 0.0014
531 Aldehyde dehydrogenase X, mitochondrial ALDH1B1 0.0014
107 C-4 methylsterol oxidase SC4MOL 0.0014
258 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial ALDH6A1 0.0014
271 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial ALDH4A1 0.0014
487 Aldo-keto reductase family 1 member C4 AKR1C4 0.0014
637 NADH-ubiquinone oxidoreductase chain 5 MT-ND5 0.0014
206 3-keto-steroid reductase HSD17B7 0.0014
671 Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial PDHA2 0.0014
643 Peroxisomal bifunctional enzyme EHHADH 0.0014
548 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NDUFS1 0.0014
288 Trifunctional enzyme subunit alpha, mitochondrial HADHA 0.0014
646 Malate dehydrogenase, cytoplasmic MDH1 0.0014
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0014
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.0014
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0014
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.0014
4386 Hemoglobin-like protein HbN glbN 0.0014
396 Alcohol dehydrogenase 4 ADH4 0.0014
328 Sorbitol dehydrogenase SORD 0.0014
597 Dihydropteridine reductase QDPR 0.0014
363 NADP-dependent malic enzyme, mitochondrial ME3 0.0014
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.0014
2599 Tyrosine-protein kinase HCK HCK 0.0014
3760 Penicillin-binding protein 5 precursor dacA 0.0014
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.0014
666 NADP-dependent malic enzyme ME1 0.0014
6859 Protein S100-A4 S100A4 0.0014
6002 Prostaglandin E2 receptor EP4 subtype PTGER4 0.0013
857 Malate dehydrogenase, mitochondrial MDH2 0.0013
677 Choline-phosphate cytidylyltransferase A PCYT1A 0.0013
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.0013
1313 Lactoylglutathione lyase GLO1 0.0013
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0013
6184 D-alanyl-D-alanine carboxypeptidase dacC dacC 0.0013
77 L-lactate dehydrogenase B chain LDHB 0.0013
12 Alcohol dehydrogenase class 3 ADH5 0.0013
11 NAD(P) transhydrogenase, mitochondrial NNT 0.0013
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0013
6211 Tubulin epsilon chain TUBE1 0.0013
6212 Tubulin gamma-1 chain TUBG1 0.0013
6210 Tubulin delta chain TUBD1 0.0013
2077 Caspase-3 CASP3 0.0013
3221 Cytochrome c4 cc4 0.0013
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0013
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0013
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0013
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0013
74 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial DLAT 0.0013
4131 Prostaglandin E2 receptor, EP3 subtype PTGER3 0.0013
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0013
860 Nicotinamide N-methyltransferase NNMT 0.0013
699 Nicotinic acid receptor 1 GPR109A 0.0013
928 Nicotinic acid receptor 2 GPR109B 0.0013
583 Nicotinate-nucleotide pyrophosphorylase [carboxylating] QPRT 0.0013
2442 Nicotinate-nucleotide pyrophosphorylase [carboxylating] nadC 0.0013
2459 Nicotinate-nucleotide pyrophosphorylase [carboxylating] nadC 0.0013
6116 Gastric triacylglycerol lipase LIPF 0.0012
406 Prostaglandin E2 receptor, EP2 subtype PTGER2 0.0012
819 Penicillin-binding protein 4 dacB 0.0012
6026 Alcohol dehydrogenase 6 ADH6 0.0012
627 11-cis retinol dehydrogenase RDH5 0.0012
296 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial MTHFD2 0.0012
57 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I HSD3B1 0.0012
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0012
640 Aldehyde dehydrogenase 1A3 ALDH1A3 0.0012
3823 Cytokine receptor common gamma chain IL2RG 0.0012
2298 Cytochrome P450-cam camC 0.0012
2107 Microtubule-associated protein 1A MAP1A 0.0012
248 Pyrroline-5-carboxylate reductase 1 PYCR1 0.0012
802 Pyrroline-5-carboxylate reductase 2 PYCR2 0.0012
13 Aminomethyltransferase, mitochondrial AMT 0.0012
110 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.0012
1768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit GNG2 0.0012
1295 Fatty acid synthase FASN 0.0012
1268 Neuropeptide S receptor NPSR1 0.0012
1571 G protein-activated inward rectifier potassium channel 1 KCNJ3 0.0012
1581 G protein-activated inward rectifier potassium channel 2 KCNJ6 0.0012
626 Cysteine dioxygenase type 1 CDO1 0.0012
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0012
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0012
702 UMP-CMP kinase CMPK1 0.0012
5433 UPF0230 protein TM_1468 TM_1468 0.0012
5431 Lipid binding protein Not Available 0.0012
3616 Fatty acid-binding protein, epidermal FABP5 0.0012
5430 Hepatocyte nuclear factor 4-gamma HNF4G 0.0012
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0012
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0011
935 Proto-oncogene tyrosine-protein kinase Yes YES1 0.0011
1063 Signal transducer and activator of transcription 5B STAT5B 0.0011
2461 D-alanyl-D-alanine carboxypeptidase Not Available 0.0011
5756 D-alanyl-D-alanine carboxypeptidase dac 0.0011
754 Pancreatic triacylglycerol lipase PNLIP 0.0011
6073 Potassium channel subfamily K member 9 KCNK9 0.0011
6072 Potassium channel subfamily K member 3 KCNK3 0.0011
4920 Peroxidase/catalase katG 0.0011
2178 Metabotropic glutamate receptor 5 GRM5 0.0011
724 Interleukin-2 receptor alpha chain IL2RA 0.0011
717 Interleukin-2 receptor subunit beta IL2RB 0.0011
2119 Cytochrome b5 CYB5A 0.0011
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.001
4990 PpcA ppcA 0.001
4988 Sulfite oxidase, mitochondrial SUOX 0.001
3375 Acidic cytochrome c3 Not Available 0.001
4385 Cytochrome c' Not Available 0.001
4967 Cytochrome c' cycA 0.001
5038 Cytochrome c' Not Available 0.001
5223 Cytochrome c' cycP 0.001
2915 Sensor protein fixL fixL 0.001
4944 Sensor protein fixL fixL 0.001
4037 Hypothetical protein GPX1 0.001
4297 Hypothetical protein SP_1951 0.001
4521 Hypothetical protein BC_2969 0.001
4540 Hypothetical protein TM_1070 0.001
4555 Hypothetical protein MT1739 0.001
4569 Hypothetical protein mshD 0.001
4578 Hypothetical protein PA3270 0.001
4747 Hypothetical protein PA3967 0.001
5177 Hypothetical protein TM_0096 0.001
5194 Hypothetical protein PA1204 0.001
5240 Hypothetical protein Rv2991 0.001
5370 Hypothetical protein TM_1158 0.001
5710 Hypothetical protein Tb927.5.1360 0.001
3570 Cytochrome P450 152A1 cypC 0.001
4992 Cytochrome c peroxidase Not Available 0.001
4813 Heme oxygenase hmuO 0.001
5769 Heme oxygenase Not Available 0.001
4289 Cytochrome P450 TT_P0059 0.001
6262 Cytochrome P450 staP 0.001
1810 Protein S100-A1 S100A1 0.001
6097 Protein S100-A2 S100A2 0.001
2230 Catalase CAT 0.001
3249 Catalase katA 0.001
3625 Catalase katA 0.001
4539 Catalase katA 0.001
4941 Catalase katB 0.001
279 Tyrosinase TYR 0.001
997 Protein kinase C beta type PRKCB 0.001
493 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 0.001
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.001
283 SEC14-like protein 2 SEC14L2 0.001
934 Proto-oncogene tyrosine-protein kinase Fyn FYN 0.001
4041 Microsomal glutathione S-transferase 2 MGST2 0.001
6151 Monocarboxylate transporter 10 SLC16A10 0.001
6837 Serine/threonine-protein kinase 17B STK17B 0.001
6836 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial HIBCH 0.001
6163 Copper-transporting ATPase 2 ATP7B 0.001
6165 Copper-transporting ATPase 1 ATP7A 0.001
1970 Protein kinase C alpha type PRKCA 0.001
5432 Trafficking protein particle complex subunit 3 TRAPPC3 0.0009
2211 Fatty acid-binding protein, heart FABP3 0.0009
6459 Glycodelin PAEP 0.0009
2408 Tyrosine-protein kinase SYK SYK 0.0009
484 Tyrosine-protein kinase ABL2 ABL2 0.0009
1064 DNA (cytosine-5)-methyltransferase 1 DNMT1 0.0009
3670 Soluble cytochrome b562 precursor cybC 0.0009
3411 Cytochrome P450 121 cyp121 0.0009
76 Nitric-oxide synthase, brain NOS1 0.0009
3291 Cytochrome c-552 cycA 0.0009
4927 Cytochrome c-552 nrfA 0.0009
4938 Cytochrome c-552 cycA 0.0009
4953 Cytochrome c-552 nrfA 0.0009
5217 Cytochrome c-552 cycM 0.0009
2617 Nitric oxide synthase oxygenase nos 0.0009
2701 Nitric oxide synthase oxygenase nos 0.0009
1048 Protein S100-A13 S100A13 0.0009
2226 Protein S100-A12 S100A12 0.0009
1759 85 kDa calcium-independent phospholipase A2 PLA2G6 0.0009
1770 Phospholipase C PLCL1 0.0009
2841 Phospholipase C plc 0.0009
3102 Flavohemoprotein hmp 0.0009
4969 Flavohemoprotein hmp 0.0009
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0009
6677 Myelin P2 protein PMP2 0.0009
2132 Protein S100-B S100B 0.0009
6656 UDP-glucuronosyltransferase 3A1 UGT3A1 0.0008
5818 Folate receptor alpha FOLR1 0.0008
2972 6-deoxyerythronolide B hydroxylase eryF 0.0008
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0008
3587 Gastrotropin FABP6 0.0008
4031 Glutathione S-transferase A1 GSTA1 0.0008
6599 HTH-type transcriptional regulator ttgR ttgR 0.0008
500 Monocarboxylate transporter 4 SLC16A3 0.0008
1649 Small inducible cytokine A2 CCL2 0.0008
4608 Putative cytochrome P450 SCO1207 0.0008
4963 Putative cytochrome P450 SCO2884 0.0008
6254 Putative cytochrome P450 SCO6998 0.0008
400 Coagulation factor IX F9 0.0008
5461 Coagulation factor IX F9 0.0008
6893 Calcium/calmodulin-dependent protein kinase type II gamma chain CAMK2G 0.0007
866 Large neutral amino acids transporter small subunit 2 SLC7A8 0.0007
358 Cystathionine beta-synthase CBS 0.0007
461 Glycine receptor subunit alpha-3 GLRA3 0.0007
4081 Vitamin K epoxide reductase complex subunit 1-like protein 1 VKORC1L1 0.0007
604 Vitamin K-dependent protein Z PROZ 0.0007
6228 Nuclear receptor coactivator 1 NCOA1 0.0007
6344 ATP synthase subunit gamma, mitochondrial ATP5C1 0.0007
6343 ATP synthase subunit beta, mitochondrial ATP5B 0.0007
6342 ATP synthase subunit alpha, mitochondrial ATP5A1 0.0007
6134 Sodium channel subunit beta-3 SCN3B 0.0007
6133 Sodium channel subunit beta-2 SCN2B 0.0007
6135 Sodium channel subunit beta-4 SCN4B 0.0007
6241 Nuclear receptor coactivator 2 NCOA2 0.0007
6132 Sodium channel subunit beta-1 SCN1B 0.0007
6129 Carbonic anhydrase-related protein 11 CA11 0.0007
6127 Carbonic anhydrase-related protein CA8 0.0007
6128 Carbonic anhydrase-related protein 10 CA10 0.0007
693 Hemoglobin subunit beta HBB 0.0007
3876 Aromatic-L-amino-acid decarboxylase DDC 0.0007
226 Gonadotropin-releasing hormone receptor GNRHR 0.0007
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0007
125 DNA polymerase beta POLB 0.0007
6268 Hydroxyacid oxidase 1 HAO1 0.0006
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0006
1245 Vitamin K-dependent protein S PROS1 0.0006
422 Vitamin K-dependent protein C PROC 0.0006
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0006
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.0006
6259 (3R)-hydroxymyristoyl-acyl carrier protein dehydratase fabZ 0.0006
6130 Carbonic anhydrase 13 CA13 0.0006
890 Niemann-Pick C1-like protein 1 NPC1L1 0.0006
2404 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PIK3CG 0.0006
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.0006
6168 Solute carrier family 22 member 16 SLC22A16 0.0006
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0006
1569 G1/S-specific cyclin-D1 CCND1 0.0006
5221 Cytochrome c3, 13 kDa Not Available 0.0006
3152 Cytochrome c'' cycA 0.0006
5220 Split-Soret cytochrome c Ddes_2150 0.0006
3700 Cytochrome c-552 precursor nrfA 0.0006
1760 Aminopeptidase N ANPEP 0.0005
6843 Aminopeptidase N pepN 0.0005
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0005
798 Osteocalcin BGLAP 0.0005
3127 Nitrite reductase nirS 0.0005
3284 Nitrite reductase nirS 0.0005
369 Coagulation factor VII F7 0.0005
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0004
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0004
476 RAC-alpha serine/threonine-protein kinase AKT1 0.0004
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0004
3405 Quinohaemoprotein ethanol dehydrogenase type-1 qheDH 0.0004
1176 Mitogen-activated protein kinase 1 MAPK1 0.0004
2240 Cell division protein kinase 2 CDK2 0.0003
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