DT-Web

DB00925 - Phenoxybenzamine


Identification
Name Phenoxybenzamine
Accession Number DB00925 (APRD00651)
Type small molecule
Description An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator. [PubChem]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 303.826
Groups approved
Monoisotopic Weight 303.138992038
Pharmacology
Indication For the treatment of phaeochromocytoma (malignant), benign prostatic hypertrophy and malignant essential hypertension.
Mechanism of action Phenoxybenzamine produces its therapeutic actions by blocking alpha receptors, leading to a muscle relaxation and a widening of the blood vessels. This widening of the blood vessels results in a lowering of blood pressure.
Absorption Twenty to 30 percent of orally administered phenoxybenzamine appears to be absorbed in the active form.
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Symptoms of overdose are largely the result of block of the sympathetic nervous system and of the circulating epinephrine. They may include postural hypotension resulting in dizziness or fainting, tachycardia, particularly postural, vomiting; lethargy, and shock.
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions
Drug Mechanism of interaction
Tadalafil Tadalafil may enhance the hypotensive effect of Phenoxybenzamine. Monitor for hypotension during concomitant therapy.
Tamsulosin Concomitant use of alpha1-adrenergic antagonists, Tamsulosin and Phenoxybenzamine, may result in additive antihypertensive effects. Combination therapy is not recommended.
Treprostinil Additive hypotensive effect. Monitor antihypertensive therapy during concomitant use.
Vardenafil Additive hypotensive effects of the PDE5 inhibitor, Vardenafil, and alpha1-blocker, Phenoxybenzamine, may occur. Monitor for hypotension during concomitant therapy.
Food Interactions Not Available

Targets


Alpha-1A adrenergic receptor
Name Alpha-1A adrenergic receptor
Gene Name ADRA1A
Pharmacological action yes
Actions antagonist
References
  • Stam WB, Van der Graaf PH, Saxena PR: Analysis of alpha 1L-adrenoceptor pharmacology in rat small mesenteric artery. Br J Pharmacol. 1999 Jun;127(3):661-70. - Pubmed
  • Michel MC, Hanft G, Gross G: Functional studies on alpha 1-adrenoceptor subtypes mediating inotropic effects in rat right ventricle. Br J Pharmacol. 1994 Feb;111(2):539-46. - Pubmed
  • Yu Y, Koss MC: Functional characterization of alpha-adrenoceptors mediating pupillary dilation in rats. Eur J Pharmacol. 2003 Jun 20;471(2):135-40. - Pubmed
  • Salles J, Gascon S, Badia A: Sustained increase in rat myocardial alpha 1A-adrenoceptors induced by 6-hydroxydopamine treatment involves a decelerated receptor turnover. Naunyn Schmiedebergs Arch Pharmacol. 1996 Mar;353(4):408-16. - Pubmed
  • Suzuki E, Tsujimoto G, Tamura K, Hashimoto K: Two pharmacologically distinct alpha 1-adrenoceptor subtypes in the contraction of rabbit aorta: each subtype couples with a different Ca2+ signalling mechanism and plays a different physiological role. Mol Pharmacol. 1990 Nov;38(5):725-36. - Pubmed
DTHybrid score 0.4955
Alpha-2A adrenergic receptor
Name Alpha-2A adrenergic receptor
Gene Name ADRA2A
Pharmacological action yes
Actions antagonist
References
  • Frang H, Cockcroft V, Karskela T, Scheinin M, Marjamaki A: Phenoxybenzamine binding reveals the helical orientation of the third transmembrane domain of adrenergic receptors. J Biol Chem. 2001 Aug 17;276(33):31279-84. Epub 2001 Jun 6. - Pubmed
DTHybrid score 0.5389
Alpha-2C adrenergic receptor
Name Alpha-2C adrenergic receptor
Gene Name ADRA2C
Pharmacological action unknown
Actions antagonist
References
  • Frang H, Cockcroft V, Karskela T, Scheinin M, Marjamaki A: Phenoxybenzamine binding reveals the helical orientation of the third transmembrane domain of adrenergic receptors. J Biol Chem. 2001 Aug 17;276(33):31279-84. Epub 2001 Jun 6. - Pubmed
DTHybrid score 0.3427
Alpha-2B adrenergic receptor
Name Alpha-2B adrenergic receptor
Gene Name ADRA2B
Pharmacological action unknown
Actions antagonist
References
  • Frang H, Cockcroft V, Karskela T, Scheinin M, Marjamaki A: Phenoxybenzamine binding reveals the helical orientation of the third transmembrane domain of adrenergic receptors. J Biol Chem. 2001 Aug 17;276(33):31279-84. Epub 2001 Jun 6. - Pubmed
DTHybrid score 0.3405
Calmodulin
Name Calmodulin
Gene Name CALM1
Pharmacological action unknown
Actions inhibitor
References
  • Cimino M, Weiss B: Characteristics of the binding of phenoxybenzamine to calmodulin. Biochem Pharmacol. 1988 Jul 15;37(14):2739-45. - Pubmed
  • Suko J, Wyskovsky W, Pidlich J, Hauptner R, Plank B, Hellmann G: Calcium release from calmodulin and its C-terminal or N-terminal halves in the presence of the calmodulin antagonists phenoxybenzamine and melittin measured by stopped-flow fluorescence with Quin 2 and intrinsic tyrosine. Inhibition of calmodulin-dependent protein kinase of cardiac sarcoplasmic reticulum. Eur J Biochem. 1986 Sep 15;159(3):425-34. - Pubmed
  • Lukas TJ, Marshak DR, Watterson DM: Drug-protein interactions: isolation and characterization of covalent adducts of phenoxybenzamine and calmodulin. Biochemistry. 1985 Jan 1;24(1):151-7. - Pubmed
  • Earl CQ, Prozialeck WC, Weiss B: Interaction of alpha adrenergic antagonists with calmodulin. Life Sci. 1984 Jul 30;35(5):525-34. - Pubmed
  • Kuromi H, Yoshihara M, Kidokoro Y: An inhibitory role of calcineurin in endocytosis of synaptic vesicles at nerve terminals of Drosophila larvae. Neurosci Res. 1997 Feb;27(2):101-13. - Pubmed
DTHybrid score 0.3976
Beta-2 adrenergic receptor
Name Beta-2 adrenergic receptor
Gene Name ADRB2
Pharmacological action unknown
Actions Not Available
References
  • Frang H, Cockcroft V, Karskela T, Scheinin M, Marjamaki A: Phenoxybenzamine binding reveals the helical orientation of the third transmembrane domain of adrenergic receptors. J Biol Chem. 2001 Aug 17;276(33):31279-84. Epub 2001 Jun 6. - Pubmed
DTHybrid score 0.5636

Enzymes


Cytochrome P450 3A4
Name Cytochrome P450 3A4
Gene Name CYP3A4
Actions substrate
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.4355

Transporters


Solute carrier family 22 member 2
Name Solute carrier family 22 member 2
Gene Name SLC22A2
Actions inhibitor
References
  • Hayer-Zillgen M, Bruss M, Bonisch H: Expression and pharmacological profile of the human organic cation transporters hOCT1, hOCT2 and hOCT3. Br J Pharmacol. 2002 Jul;136(6):829-36. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.3033
Solute carrier family 22 member 1
Name Solute carrier family 22 member 1
Gene Name SLC22A1
Actions inhibitor
References
  • Hayer-Zillgen M, Bruss M, Bonisch H: Expression and pharmacological profile of the human organic cation transporters hOCT1, hOCT2 and hOCT3. Br J Pharmacol. 2002 Jul;136(6):829-36. - Pubmed
DTHybrid score 0.3594
Solute carrier family 22 member 3
Name Solute carrier family 22 member 3
Gene Name SLC22A3
Actions inhibitor
References
  • Hayer-Zillgen M, Bruss M, Bonisch H: Expression and pharmacological profile of the human organic cation transporters hOCT1, hOCT2 and hOCT3. Br J Pharmacol. 2002 Jul;136(6):829-36. - Pubmed
DTHybrid score 0.2387

Predictions


Id Partner name Gene Name Score
4119 Cytochrome P450 2D6 CYP2D6 0.3142
193 Beta-1 adrenergic receptor ADRB1 0.3028
1588 Multidrug resistance protein 1 ABCB1 0.2107
632 Alpha-1B adrenergic receptor ADRA1B 0.1991
4200 Cytochrome P450 1A2 CYP1A2 0.199
831 D(2) dopamine receptor DRD2 0.1722
23 D(1A) dopamine receptor DRD1 0.1672
502 5-hydroxytryptamine 2A receptor HTR2A 0.1607
320 5-hydroxytryptamine 1A receptor HTR1A 0.1575
789 Alpha-1D adrenergic receptor ADRA1D 0.1387
4118 Cytochrome P450 3A5 CYP3A5 0.1257
6016 Cytochrome P450 2C19 CYP2C19 0.1256
4757 Cytochrome P450 2C9 CYP2C9 0.1224
118 Organic cation/carnitine transporter 2 SLC22A5 0.1158
540 Sodium-dependent noradrenaline transporter SLC6A2 0.1141
638 D(3) dopamine receptor DRD3 0.1104
590 5-hydroxytryptamine 2C receptor HTR2C 0.1099
492 Histamine H1 receptor HRH1 0.1084
163 D(1B) dopamine receptor DRD5 0.1054
1517 Beta-3 adrenergic receptor ADRB3 0.1035
432 D(4) dopamine receptor DRD4 0.1032
885 5-hydroxytryptamine 1B receptor HTR1B 0.102
725 5-hydroxytryptamine 1D receptor HTR1D 0.0959
6107 Cytochrome P450 3A7 CYP3A7 0.0921
6030 Cytochrome P450 2B6 CYP2B6 0.0805
833 Organic cation/carnitine transporter 1 SLC22A4 0.0792
6013 Cytochrome P450 2E1 CYP2E1 0.0785
3923 Cholinesterase BCHE 0.0758
824 Sodium-dependent serotonin transporter SLC6A4 0.0744
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0743
4924 Cytochrome P450 2C8 CYP2C8 0.0732
131 Synaptic vesicular amine transporter SLC18A2 0.0706
6024 Cytochrome P450 1A1 CYP1A1 0.0701
713 Sodium-dependent dopamine transporter SLC6A3 0.0681
436 5-hydroxytryptamine 2B receptor HTR2B 0.064
716 5-hydroxytryptamine 7 receptor HTR7 0.0605
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0595
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0576
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0572
6070 Nischarin NISCH 0.0569
3941 Amine oxidase [flavin-containing] A MAOA 0.0527
6142 Solute carrier family 22 member 8 SLC22A8 0.0519
587 Serum albumin ALB 0.0506
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0504
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0491
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.049
5718 Cytochrome P450 2A6 CYP2A6 0.0473
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0467
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0444
220 Sodium channel protein type 5 subunit alpha SCN5A 0.044
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.044
828 Phenylalanine-4-hydroxylase PAH 0.0428
3109 Phenylalanine-4-hydroxylase phhA 0.0428
341 5-hydroxytryptamine 3 receptor HTR3A 0.0416
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0394
124 Histamine H2 receptor HRH2 0.0389
3939 Amine oxidase [flavin-containing] B MAOB 0.0376
1256 5-hydroxytryptamine 6 receptor HTR6 0.0374
1507 Cytochrome c CYCS 0.0356
1729 Solute carrier family 22 member 6 SLC22A6 0.0356
862 Multidrug resistance-associated protein 1 ABCC1 0.0354
722 Troponin I, cardiac muscle TNNI3 0.0347
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0305
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0301
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0299
6020 Aldehyde oxidase AOX1 0.0291
776 Bile salt export pump ABCB11 0.0284
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0278
1636 Trace amine-associated receptor 1 TAAR1 0.0271
281 5'-AMP-activated protein kinase subunit beta-1 PRKAB1 0.0264
2300 Lysozyme E 0.0261
3633 Lysozyme R 0.0261
5597 Lysozyme 17 0.0261
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0257
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0257
1898 Cytochrome P450 1B1 CYP1B1 0.025
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0246
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0245
3811 Cytochrome P450 19A1 CYP19A1 0.0243
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0242
528 5-hydroxytryptamine 1E receptor HTR1E 0.0242
3810 Catechol O-methyltransferase COMT 0.0237
6106 Cytochrome P450 2C18 CYP2C18 0.0234
3876 Aromatic-L-amino-acid decarboxylase DDC 0.0233
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0218
474 Acetylcholinesterase ACHE 0.0216
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0215
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0211
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0208
6143 Solute carrier family 22 member 7 SLC22A7 0.0207
136 Estrogen receptor ESR1 0.0202
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0199
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0183
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0183
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.018
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0179
2164 Multidrug resistance-associated protein 4 ABCC4 0.0178
20 Prostaglandin G/H synthase 1 PTGS1 0.0178
5682 Ribonuclease pancreatic RNASE1 0.0173
1024 Solute carrier family 22 member 11 SLC22A11 0.0172
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0171
6148 Multidrug resistance-associated protein 7 ABCC10 0.0169
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0168
1089 Cartilage oligomeric matrix protein COMP 0.0168
1108 Calpastatin CAST 0.0168
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0167
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0167
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0166
3947 Xanthine dehydrogenase/oxidase XDH 0.0165
164 Histamine H4 receptor HRH4 0.0165
871 Glucocorticoid receptor NR3C1 0.0163
4773 Deoxycytidine kinase DCK 0.0163
6048 Troponin C, skeletal muscle TNNC2 0.0161
6010 Thiamine transporter 1 SLC19A2 0.0159
2472 Voltage-gated potassium channel kcsA 0.0157
6366 Voltage-gated potassium channel kcsA 0.0157
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0149
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.0149
2392 Biphenyl-2,3-diol 1,2-dioxygenase bphC 0.0146
3032 Biphenyl-2,3-diol 1,2-dioxygenase bphC 0.0146
696 Kappa-type opioid receptor OPRK1 0.0146
677 Choline-phosphate cytidylyltransferase A PCYT1A 0.0145
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0144
5626 Nucleoside diphosphate kinase B NME2 0.0143
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.0142
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.0142
175 Thiamin pyrophosphokinase 1 TPK1 0.0142
241 Calcium-transporting ATPase type 2C member 1 ATP2C1 0.0142
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0142
467 Delta-type opioid receptor OPRD1 0.0141
847 Mu-type opioid receptor OPRM1 0.0141
161 Tubulin beta chain TUBB 0.014
312 Tubulin beta chain TUB2 0.014
4203 Histamine N-methyltransferase HNMT 0.0136
731 HIV-1 protease HIV-1 protease 0.0134
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0133
1064 DNA (cytosine-5)-methyltransferase 1 DNMT1 0.013
748 5'-AMP-activated protein kinase catalytic subunit alpha-1 PRKAA1 0.013
6859 Protein S100-A4 S100A4 0.0129
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0128
6136 Multidrug resistance-associated protein 5 ABCC5 0.0127
672 Prostaglandin F2-alpha receptor PTGFR 0.0125
5126 Arginase rocF 0.0125
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0124
2314 Triosephosphate isomerase TPI 0.0123
3417 Triosephosphate isomerase tpiA 0.0123
3443 Triosephosphate isomerase tpiA 0.0123
6346 Triosephosphate isomerase TPI1 0.0123
1341 Histamine H3 receptor HRH3 0.0122
6138 Multidrug resistance protein 3 ABCB4 0.0119
6432 Transporter snf 0.0118
2795 Methionine aminopeptidase 2 METAP2 0.0117
4209 ATP-sensitive inward rectifier potassium channel 8 KCNJ8 0.0116
756 Sex hormone-binding globulin SHBG 0.0115
5294 Nucleoside diphosphate kinase A NME1 0.0115
7 Nitric oxide synthase, inducible NOS2 0.0114
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0112
740 Argininosuccinate synthase ASS1 0.0111
865 Argininosuccinate synthase ASS1 0.0111
2680 Argininosuccinate synthase argG 0.0111
3194 Argininosuccinate synthase argG 0.0111
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0111
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.011
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0108
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0106
233 Potassium channel subfamily K member 2 KCNK2 0.0105
6141 Sodium/bile acid cotransporter SLC10A1 0.0105
2132 Protein S100-B S100B 0.0105
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0104
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.0104
982 Cocaine- and amphetamine-regulated transcript protein CARTPT 0.0101
614 Progesterone receptor PGR 0.0101
4120 NADPH--cytochrome P450 reductase POR 0.0101
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0098
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0098
6151 Monocarboxylate transporter 10 SLC16A10 0.0097
624 Guanidinoacetate N-methyltransferase GAMT 0.0097
509 Thymidine kinase TK 0.0097
570 Thymidine kinase TK 0.0097
2559 Thymidine kinase TK 0.0097
3430 Thymidine kinase tdk 0.0097
3518 Thymidine kinase TK 0.0097
5301 Thymidine kinase tdk 0.0097
5771 Thymidine kinase ORF36 0.0097
7009 Thymidine kinase ORF36 0.0097
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0096
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0096
6014 Cytochrome P450 2A13 CYP2A13 0.0095
1757 Myeloperoxidase MPO 0.0093
737 Mineralocorticoid receptor NR3C2 0.0092
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0091
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0091
342 P protein [Includes: DNA-directed DNA polymerase P 0.0091
612 P protein [Includes: DNA-directed DNA polymerase P 0.0091
741 Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 0.0091
3426 Glutamine synthetase glnA 0.009
3987 Glutamine synthetase GLUL 0.009
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.009
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0089
1680 Solute carrier family 2, facilitated glucose transporter member 1 SLC2A1 0.0089
1360 Sphingomyelin phosphodiesterase SMPD1 0.0087
6137 Multidrug resistance-associated protein 6 ABCC6 0.0087
29 Tubulin beta-1 chain TUBB1 0.0086
694 Matrix protein 2 M 0.0086
338 DNA polymerase UL30 0.0086
379 DNA polymerase UL54 0.0086
697 DNA polymerase ORF28 0.0086
2482 DNA polymerase 43 0.0086
4104 DNA polymerase BALF5 0.0086
1830 5'-nucleotidase NT5E 0.0084
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0083
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0081
1820 Beta-nerve growth factor NGF 0.0081
125 DNA polymerase beta POLB 0.0081
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0081
6146 High affinity copper uptake protein 1 SLC31A1 0.0081
6165 Copper-transporting ATPase 1 ATP7A 0.008
6163 Copper-transporting ATPase 2 ATP7B 0.008
232 Corticosteroid-binding globulin SERPINA6 0.008
705 Glutamate receptor 1 GRIA1 0.008
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0079
817 DNA topoisomerase 2-alpha TOP2A 0.0077
3704 Spermidine/putrescine-binding periplasmic protein precursor potD 0.0077
777 Tumor necrosis factor TNF 0.0077
908 Glutathione S-transferase theta-1 GSTT1 0.0076
477 DNA topoisomerase 4 subunit A parC 0.0075
886 DNA topoisomerase 4 subunit A parC 0.0075
6226 DNA topoisomerase 4 subunit A parC 0.0075
869 Estrogen receptor beta ESR2 0.0075
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0074
4146 Phosphatidylinositol 3-kinase regulatory subunit gamma PIK3R3 0.0074
404 DNA gyrase subunit A gyrA 0.0074
6224 DNA gyrase subunit A gyrA 0.0074
4145 Phosphatidylinositol 3-kinase regulatory subunit beta PIK3R2 0.0074
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0073
702 UMP-CMP kinase CMPK1 0.0072
896 Glutathione S-transferase Mu 1 GSTM1 0.0072
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0072
3611 Cytidine deaminase cdd 0.0071
3707 Cytidine deaminase cdd 0.0071
4211 Cytidine deaminase CDA 0.0071
6171 Solute carrier family 28 member 3 SLC28A3 0.007
153 Dopamine beta-hydroxylase DBH 0.007
3929 Phosphoethanolamine/phosphocholine phosphatase PHOSPHO1 0.007
3927 Choline transporter-like protein 3 SLC44A3 0.007
3926 Choline transporter-like protein 2 SLC44A2 0.007
3933 Choline/ethanolaminephosphotransferase CEPT1 0.007
549 Choline-phosphate cytidylyltransferase B PCYT1B 0.007
1686 Choline transporter-like protein 1 SLC44A1 0.007
264 Choline/ethanolamine kinase [Includes: Choline kinase beta CHKB 0.007
861 Choline kinase alpha CHKA 0.007
769 High-affinity choline transporter 1 SLC5A7 0.007
3925 Choline transporter-like protein 4 SLC44A4 0.007
700 Choline dehydrogenase, mitochondrial CHDH 0.007
576 Choline O-acetyltransferase CHAT 0.007
3922 Phospholipase D2 PLD2 0.007
3924 Phospholipase D1 PLD1 0.007
1262 Corticotropin-lipotropin POMC 0.007
904 Glutathione S-transferase P GSTP1 0.0069
260 Cytochrome P450 51 ERG11 0.0069
761 Cytochrome P450 51 ERG11 0.0069
3163 Cytochrome P450 51 cyp51 0.0069
6031 Cytochrome P450 3A43 CYP3A43 0.0069
290 Prostaglandin G/H synthase 2 PTGS2 0.0069
3560 Gentamicin 3'-acetyltransferase aacC1 0.0067
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0067
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0066
749 Amiloride-sensitive cation channel 1, neuronal ACCN1 0.0066
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0066
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0064
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0064
1759 85 kDa calcium-independent phospholipase A2 PLA2G6 0.0064
1770 Phospholipase C PLCL1 0.0064
2841 Phospholipase C plc 0.0064
723 Cytosolic phospholipase A2 PLA2G4A 0.0063
2539 Tubulin alpha-1 chain TUBA4A 0.0063
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0062
537 ATP synthase delta chain, mitochondrial ATP5D 0.0062
380 Cytochrome P450 17A1 CYP17A1 0.0062
482 Glycine receptor subunit alpha-1 GLRA1 0.0062
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0061
1281 Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 0.006
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.006
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.006
738 Monocarboxylate transporter 1 SLC16A1 0.0059
4148 Serine/threonine-protein kinase mTOR MTOR 0.0059
387 Amiloride-sensitive amine oxidase [copper-containing] ABP1 0.0059
7187 Amiloride-sensitive amine oxidase [copper-containing] ABP1 0.0059
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0059
1656 CYP2B protein CYP2B 0.0059
818 50S ribosomal protein L10 rplJ 0.0058
213 Amiloride-sensitive sodium channel subunit alpha SCNN1A 0.0058
550 Amiloride-sensitive sodium channel subunit delta SCNN1D 0.0058
6111 DNA polymerase epsilon subunit 4 POLE4 0.0058
827 Sodium/hydrogen exchanger 1 SLC9A1 0.0058
27 Amiloride-sensitive sodium channel subunit beta SCNN1B 0.0058
552 Amiloride-sensitive sodium channel subunit gamma SCNN1G 0.0058
6112 DNA polymerase epsilon subunit 3 POLE3 0.0058
6108 Ribonucleoside-diphosphate reductase subunit M2 B RRM2B 0.0058
6110 DNA polymerase epsilon subunit 2 POLE2 0.0058
6109 DNA polymerase epsilon catalytic subunit A POLE 0.0058
6085 Fatty acid-binding protein, intestinal FABP2 0.0057
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0056
362 Melatonin receptor type 1B MTNR1B 0.0054
571 Melatonin receptor type 1A MTNR1A 0.0054
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0054
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0054
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0054
102 DNA topoisomerase I, mitochondrial TOP1MT 0.0054
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.0054
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0054
3830 Calreticulin CALR 0.0053
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0053
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0053
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0053
1618 High affinity nerve growth factor receptor NTRK1 0.0053
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0053
1374 Natriuretic peptides B NPPB 0.0052
1827 Gap junction alpha-1 protein GJA1 0.0052
146 Androgen receptor AR 0.0052
1908 Vascular cell adhesion protein 1 VCAM1 0.0052
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.0051
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0051
6035 Nuclear receptor ROR-beta RORB 0.005
6034 Hydroxyindole O-methyltransferase ASMT 0.005
6036 Eosinophil peroxidase EPX 0.005
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.005
976 Platelet glycoprotein IX GP9 0.005
4218 Ribonucleoside-diphosphate reductase M2 subunit RRM2 0.005
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.005
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.0049
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0049
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.0049
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0049
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0049
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.0049
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0049
4604 Liver carboxylesterase 1 CES1 0.0049
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0048
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.0047
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0046
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0045
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0045
303 Diamine acetyltransferase 2 SAT2 0.0045
504 Mast/stem cell growth factor receptor KIT 0.0045
623 Spermine oxidase SMOX 0.0045
1317 Spermine synthase SMS 0.0045
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0045
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0045
183 Vascular endothelial growth factor A VEGFA 0.0045
468 Cytochrome P450 4A11 CYP4A11 0.0045
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0045
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0044
765 Indoleamine 2,3-dioxygenase IDO1 0.0044
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0044
1353 DNA topoisomerase 1 TOP1 0.0044
3552 DNA topoisomerase 1 topA 0.0044
603 DNA polymerase alpha catalytic subunit POLA1 0.0043
1176 Mitogen-activated protein kinase 1 MAPK1 0.0043
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0043
2449 Tubulin alpha-3 chain TUBA1A 0.0043
3755 Nucleoside-specific channel-forming protein tsx precursor tsx 0.0043
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0043
6167 Organic solute transporter subunit beta OSTB 0.0042
6166 Organic solute transporter subunit alpha OSTA 0.0042
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0042
6068 Guanylate cyclase soluble subunit alpha-2 GUCY1A2 0.0041
360 Ribonucleoside-diphosphate reductase large subunit RRM1 0.0041
5878 Alpha-7 nicotinic cholinergic receptor subunit CHRFAM7A 0.0041
228 Beta platelet-derived growth factor receptor PDGFRB 0.0041
3997 Cytochrome P450 24A1, mitochondrial CYP24A1 0.0041
950 Alpha platelet-derived growth factor receptor PDGFRA 0.004
123 Diamine acetyltransferase 1 SAT1 0.004
952 Dipeptidyl peptidase 4 DPP4 0.004
1629 Transcription factor AP-1 JUN 0.0039
1129 C-C chemokine receptor type 5 CCR5 0.0039
606 Cytochrome P450 27, mitochondrial CYP27A1 0.0038
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.0038
768 FK506-binding protein 1A FKBP1A 0.0037
1864 RET proto-oncogene RET 0.0036
527 Prostacyclin receptor PTGIR 0.0036
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0036
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0036
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0036
6182 Cytochrome P450 2J2 CYP2J2 0.0036
6211 Tubulin epsilon chain TUBE1 0.0036
6212 Tubulin gamma-1 chain TUBG1 0.0036
6210 Tubulin delta chain TUBD1 0.0036
68 Cannabinoid receptor 1 CNR1 0.0036
1074 Urokinase-type plasminogen activator PLAU 0.0036
122 P2Y purinoceptor 12 P2RY12 0.0035
856 Vitamin D3 receptor VDR 0.0035
4237 50S ribosomal protein L22 rplV 0.0035
185 Vasopressin V1a receptor AVPR1A 0.0035
939 50S ribosomal protein L3 rplC 0.0035
811 Translocator protein TSPO 0.0035
322 Vasopressin V2 receptor AVPR2 0.0034
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0034
596 3-oxo-5-alpha-steroid 4-dehydrogenase 1 SRD5A1 0.0033
277 Purine nucleoside phosphorylase PNP 0.0033
2870 Purine nucleoside phosphorylase punA 0.0033
2945 Purine nucleoside phosphorylase punA 0.0033
4659 Purine nucleoside phosphorylase TM_1596 0.0033
4825 Purine nucleoside phosphorylase TTHA1435 0.0033
6218 Pannexin-1 PANX1 0.0033
814 Ryanodine receptor 1 RYR1 0.0033
2251 Thymidylate kinase tmk 0.0033
2254 Thymidylate kinase DTYMK 0.0033
3522 Thymidylate kinase tmk 0.0033
3478 Glucose-1-phosphate thymidylyltransferase rmlA 0.0032
4277 Glucose-1-phosphate thymidylyltransferase rmlA 0.0032
751 Potassium channel subfamily K member 6 KCNK6 0.0032
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0032
592 Carbonic anhydrase 4 CA4 0.0032
215 Sodium channel protein type 11 subunit alpha SCN11A 0.0032
140 30S ribosomal protein S9 rpsI 0.0031
6719 30S ribosomal protein S9 rpsI 0.0031
6725 30S ribosomal protein S9 rpsI 0.0031
276 Sodium- and chloride-dependent GABA transporter 1 SLC6A1 0.0031
2257 Uridine phosphorylase udp 0.0031
5132 Uridine phosphorylase udp 0.0031
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0031
449 Ornithine decarboxylase ODC1 0.0031
2578 Tubulin beta-3 chain TUBB3 0.003
2285 Streptogramin A acetyltransferase vatD 0.003
80 Peroxisome proliferator-activated receptor alpha PPARA 0.003
6043 Putative G-protein coupled receptor 44 GPR44 0.003
172 Potassium channel subfamily K member 1 KCNK1 0.003
6149 Solute carrier family 22 member 10 SLC22A10 0.0029
284 DNA-directed RNA polymerase beta chain rpoB 0.0029
5773 DNA-directed RNA polymerase beta chain rpoB 0.0029
6002 Prostaglandin E2 receptor EP4 subtype PTGER4 0.0028
4217 Telomerase reverse transcriptase TERT 0.0028
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0028
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0028
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0028
4173 Tyrosine-protein kinase JAK2 JAK2 0.0027
295 Carbonic anhydrase 1 CA1 0.0027
4131 Prostaglandin E2 receptor, EP3 subtype PTGER3 0.0027
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0026
406 Prostaglandin E2 receptor, EP2 subtype PTGER2 0.0026
6100 BDNF/NT-3 growth factors receptor NTRK2 0.0026
49 Endothelin B receptor EDNRB 0.0026
407 Vascular endothelial growth factor receptor 2 KDR 0.0025
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0024
4192 DNA topoisomerase 2-beta TOP2B 0.0024
578 Endothelin-1 receptor EDNRA 0.0024
544 Potassium voltage-gated channel subfamily E member 1 KCNE1 0.0024
357 Carbonic anhydrase 2 CA2 0.0024
1483 Membrane copper amine oxidase AOC3 0.0024
6039 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A PDE11A 0.0024
5852 Type-2 angiotensin II receptor AGTR2 0.0024
642 3-oxo-5-alpha-steroid 4-dehydrogenase 2 SRD5A2 0.0023
844 Epidermal growth factor receptor EGFR 0.0023
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0023
70 Type-1 angiotensin II receptor AGTR1 0.0023
4210 Toll-like receptor 4 TLR4 0.0022
990 Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 0.0022
394 Calcineurin subunit B isoform 1 PPP3R1 0.0022
6742 Recoverin RCVRN 0.0022
6752 Guanylyl cyclase-activating protein 1 GUCA1A 0.0022
2528 Fatty acid metabolism regulator protein fadR 0.0022
6740 Fatty acid metabolism regulator protein fadR 0.0022
6753 Apolipoprotein M APOM 0.0022
6747 Chalcone/stilbene synthase family protein MT1417 0.0022
6741 Peroxisomal 3,2-trans-enoyl-CoA isomerase PECI 0.0022
6743 Non-fluorescent flavoprotein luxF 0.0022
6751 Gag polyprotein gag 0.0022
6746 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform PPP3CA 0.0022
6522 Hepatocyte nuclear factor 4-alpha HNF4A 0.0022
6749 Polyprotein Not Available 0.0022
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0022
6220 Aryl hydrocarbon receptor AHR 0.0022
259 Microsomal triglyceride transfer protein large subunit MTTP 0.0022
2320 Thymidine kinase, cytosolic TK1 0.0021
298 Renin REN 0.0021
6506 Stathmin-4 STMN4 0.0021
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0021
489 Monocarboxylate transporter 2 SLC16A7 0.0021
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.002
750 Voltage-dependent calcium channel gamma-1 subunit CACNG1 0.002
4199 Sphingosine 1-phosphate receptor Edg-8 S1PR5 0.002
5961 Insulin INS 0.002
633 Penicillin-binding proteins 1A/1B pbpA 0.0019
373 Transthyretin TTR 0.0019
3932 Glutathione S-transferase A2 GSTA2 0.0019
2499 Tubulin beta-2C chain TUBB2C 0.0019
6755 Poliovirus receptor PVR 0.0019
6527 Lymphocyte antigen 96 LY96 0.0019
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0019
6102 Arylamine N-acetyltransferase 2 NAT2 0.0018
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0018
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0018
5998 Toll-like receptor 8 TLR8 0.0018
26 Vascular endothelial growth factor receptor 3 FLT4 0.0018
4238 50S ribosomal protein L4 rplD 0.0018
5578 50S ribosomal protein L4 rplD 0.0018
6173 50S ribosomal protein L4 rplD 0.0018
6219 50S ribosomal protein L4 rplD 0.0018
712 Tubulin alpha chain TUB1 0.0018
1968 ATP-sensitive inward rectifier potassium channel 12 KCNJ12 0.0018
565 Extracellular calcium-sensing receptor CASR 0.0018
683 Potassium transporter GK0582 0.0018
6750 ADP-ribosylation factor 6 ARF6 0.0018
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0018
6524 Protein tonB tonB 0.0018
5432 Trafficking protein particle complex subunit 3 TRAPPC3 0.0018
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0018
67 Prolyl 4-hydroxylase subunit alpha-1 P4HA1 0.0017
613 Atrial natriuretic peptide receptor A NPR1 0.0017
621 Periplasmic [Fe] hydrogenase 1 Not Available 0.0017
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0017
32 Vascular endothelial growth factor receptor 1 FLT1 0.0017
543 Penicillin-binding protein 1B mrcB 0.0017
6186 Penicillin-binding protein 1B ponB 0.0017
6822 Penicillin-binding protein 1b pbp1b 0.0017
6844 Penicillin-binding protein 1b pbp1b 0.0017
1050 Bile salt sulfotransferase SULT2A1 0.0017
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0017
159 Penicillin-binding protein 2B penA 0.0017
6121 Penicillin-binding protein 2B penA 0.0017
2616 Ganglioside GM2 activator GM2A 0.0017
2435 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0016
6613 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0016
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0016
1852 Microtubule-associated protein 2 MAP2 0.0016
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0016
173 Toll-like receptor 7 TLR7 0.0016
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0016
3233 Bile acid receptor NR1H4 0.0015
2297 Genome polyprotein Not Available 0.0015
2322 Genome polyprotein Not Available 0.0015
2694 Genome polyprotein Not Available 0.0015
2719 Genome polyprotein Not Available 0.0015
2860 Genome polyprotein Not Available 0.0015
2928 Genome polyprotein Not Available 0.0015
3160 Genome polyprotein Not Available 0.0015
3260 Genome polyprotein Not Available 0.0015
4783 Genome polyprotein Not Available 0.0015
5726 Genome polyprotein Not Available 0.0015
5779 Genome polyprotein Not Available 0.0015
5867 Genome polyprotein Not Available 0.0015
6253 Genome polyprotein Not Available 0.0015
6301 Genome polyprotein Not Available 0.0015
6380 Genome polyprotein Not Available 0.0015
6381 Genome polyprotein Not Available 0.0015
6437 Genome polyprotein Not Available 0.0015
6520 Genome polyprotein Not Available 0.0015
6521 Genome polyprotein Not Available 0.0015
6652 Genome polyprotein Not Available 0.0015
6734 Genome polyprotein Not Available 0.0015
6735 Genome polyprotein Not Available 0.0015
6736 Genome polyprotein Not Available 0.0015
6737 Genome polyprotein Not Available 0.0015
6738 Genome polyprotein Not Available 0.0015
6739 Genome polyprotein Not Available 0.0015
6744 Genome polyprotein Not Available 0.0015
6748 Genome polyprotein Not Available 0.0015
6894 Genome polyprotein Not Available 0.0015
6898 Genome polyprotein Not Available 0.0015
427 Substance-P receptor TACR1 0.0015
6316 ADP-ribosylation factor 1 ARF1 0.0015
275 Arachidonate 5-lipoxygenase ALOX5 0.0015
581 Cytochrome P450 2R1 CYP2R1 0.0015
1541 Metalloproteinase mmp20 0.0014
864 Gag-Pol polyprotein gag-pol 0.0014
2237 Gag-Pol polyprotein gag-pol 0.0014
2326 Gag-Pol polyprotein gag-pol 0.0014
2451 Gag-Pol polyprotein gag-pol 0.0014
2901 Gag-Pol polyprotein gag-pol 0.0014
3165 Gag-Pol polyprotein gag-pol 0.0014
3722 Gag-Pol polyprotein gag-pol 0.0014
6306 Gag-Pol polyprotein gag-pol 0.0014
6624 Gag-Pol polyprotein gag-pol 0.0014
6032 PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) fas 0.0014
1010 Cytochrome P450 51A1 CYP51A1 0.0014
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0014
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0013
4122 Histone deacetylase 2 HDAC2 0.0013
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.0013
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0013
33 Cystine/glutamate transporter SLC7A11 0.0013
891 Dihydropteroate synthase folP 0.0013
5359 Dihydropteroate synthase folP 0.0013
7175 Dihydropteroate synthase sulI 0.0013
6116 Gastric triacylglycerol lipase LIPF 0.0012
780 Retinoic acid receptor RXR-gamma RXRG 0.0012
16 Adenosine A1 receptor ADORA1 0.0012
3806 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A 0.0012
2427 Ferrichrome-iron receptor fhuA 0.0012
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0012
3823 Cytokine receptor common gamma chain IL2RG 0.0012
85 Growth hormone receptor GHR 0.0012
6126 Carbonic anhydrase 7 CA7 0.0012
2107 Microtubule-associated protein 1A MAP1A 0.0012
6228 Nuclear receptor coactivator 1 NCOA1 0.0012
3587 Gastrotropin FABP6 0.0012
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.0012
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.0012
1295 Fatty acid synthase FASN 0.0012
6264 cAMP-dependent protein kinase inhibitor alpha PKIA 0.0011
1178 Adenosine A2a receptor ADORA2A 0.0011
239 Coagulation factor X F10 0.0011
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0011
88 Retinoic acid receptor RXR-beta RXRB 0.0011
365 Dihydrofolate reductase DHFR 0.0011
2381 Dihydrofolate reductase DFR1 0.0011
2833 Dihydrofolate reductase Not Available 0.0011
2931 Dihydrofolate reductase folA 0.0011
3544 Dihydrofolate reductase folA 0.0011
3682 Dihydrofolate reductase folA 0.0011
6642 Dihydrofolate reductase folA 0.0011
6756 Dihydrofolate reductase dfrA 0.0011
921 Glutamate receptor 2 GRIA2 0.0011
754 Pancreatic triacylglycerol lipase PNLIP 0.0011
5787 Angiopoietin-1 receptor TEK 0.0011
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0011
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0011
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0011
2178 Metabotropic glutamate receptor 5 GRM5 0.0011
724 Interleukin-2 receptor alpha chain IL2RA 0.0011
717 Interleukin-2 receptor subunit beta IL2RB 0.0011
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0011
54 Prothrombin F2 0.001
1810 Protein S100-A1 S100A1 0.001
6097 Protein S100-A2 S100A2 0.001
4116 Dihydropteroate synthetase Not Available 0.001
4228 Keratin, type II cytoskeletal 7 KRT7 0.001
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.001
1144 Hepatocyte growth factor receptor MET 0.001
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.001
493 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 0.001
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.001
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.001
512 DNA-directed RNA polymerase alpha chain rpoA 0.001
5772 DNA-directed RNA polymerase alpha chain rpoA 0.001
5300 Antigen peptide transporter 1 TAP1 0.001
4041 Microsomal glutathione S-transferase 2 MGST2 0.001
6824 Tyrosine-protein kinase Lyn LYN 0.001
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.001
605 Fumarate reductase flavoprotein subunit frdA 0.001
2709 Fumarate reductase flavoprotein subunit SO_0970 0.001
3673 Fumarate reductase flavoprotein subunit fccA 0.001
4912 Fumarate reductase flavoprotein subunit ifcA 0.001
6549 Fumarate reductase flavoprotein subunit frdA 0.001
2268 Cholesterol oxidase choB 0.0009
2822 Cholesterol oxidase choA 0.0009
6105 3-oxo-5-beta-steroid 4-dehydrogenase AKR1D1 0.0009
3086 Plasmepsin-2 Not Available 0.0009
459 Retinoic acid receptor RXR-alpha RXRA 0.0009
165 FL cytokine receptor FLT3 0.0009
1048 Protein S100-A13 S100A13 0.0009
2226 Protein S100-A12 S100A12 0.0009
1648 Elastin ELN 0.0009
6131 Carbonic anhydrase 14 CA14 0.0009
2283 Steroid Delta-isomerase ksi 0.0009
2920 Steroid Delta-isomerase ksi 0.0009
208 DNA-directed RNA polymerase beta' chain rpoC 0.0009
5774 DNA-directed RNA polymerase beta' chain rpoC 0.0009
390 Adenosine A3 receptor ADORA3 0.0009
6169 ATP-binding cassette sub-family A member 5 ABCA5 0.0009
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0008
3404 Exotoxin A eta 0.0008
22 30S ribosomal protein S4 rpsD 0.0008
6714 30S ribosomal protein S4 rpsD 0.0008
6122 Carbonic anhydrase 3 CA3 0.0008
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.0008
2325 Sulfotransferase family cytosolic 2B member 1 SULT2B1 0.0008
94 5-hydroxytryptamine 4 receptor HTR4 0.0008
1867 Major prion protein PRNP 0.0008
2232 Interleukin-5 IL5 0.0008
1593 Mucin-2 MUC2 0.0008
4031 Glutathione S-transferase A1 GSTA1 0.0008
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0008
1649 Small inducible cytokine A2 CCL2 0.0008
1025 Aquaporin-1 AQP1 0.0008
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0008
3856 Fibroblast growth factor receptor 3 FGFR3 0.0008
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0008
2091 Endoplasmin HSP90B1 0.0008
6893 Calcium/calmodulin-dependent protein kinase type II gamma chain CAMK2G 0.0007
473 L-lactate dehydrogenase A chain LDHA 0.0007
461 Glycine receptor subunit alpha-3 GLRA3 0.0007
620 Bifunctional dihydrofolate reductase-thymidylate synthase Not Available 0.0007
130 Prostacyclin synthase PTGIS 0.0007
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0007
6103 Arylamine N-acetyltransferase 1 NAT1 0.0007
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.0007
2112 Toll-like receptor 9 TLR9 0.0007
6207 30S ribosomal protein S14 rpsN 0.0007
6209 30S ribosomal protein S19 rpsS 0.0007
6712 30S ribosomal protein S19 rpsS 0.0007
6726 30S ribosomal protein S19 rpsS 0.0007
469 Annexin A1 ANXA1 0.0007
645 Penicillin-binding protein 1A mrcA 0.0007
5805 Penicillin-binding protein 1A ponA 0.0007
6185 Penicillin-binding protein 1A mrcA 0.0007
6799 Penicillin-binding protein 1A pbpA 0.0007
5924 Microtubule-associated protein 4 MAP4 0.0007
5923 Microtubule-associated protein tau MAPT 0.0007
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0007
2298 Cytochrome P450-cam camC 0.0007
518 Peroxidase/catalase T katG 0.0007
2290 ADP-ribosyl cyclase 2 BST1 0.0007
24 Thymidylate synthase TMP1 0.0007
359 Thymidylate synthase TYMS 0.0007
2626 Thymidylate synthase thyA 0.0007
2729 Thymidylate synthase thyA 0.0007
5352 Thymidylate synthase THYA 0.0007
226 Gonadotropin-releasing hormone receptor GNRHR 0.0007
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0007
4311 tRNA TRDMT1 0.0007
4325 tRNA trmD 0.0007
4328 tRNA trmD 0.0007
1123 Eosinophil cationic protein RNASE3 0.0007
2599 Tyrosine-protein kinase HCK HCK 0.0007
3937 Fatty-acid amide hydrolase FAAH 0.0006
144 Hemoglobin subunit alpha HBA1 0.0006
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0006
106 Cannabinoid receptor 2 CNR2 0.0006
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0006
6174 50S ribosomal protein L32 rpmF 0.0006
3809 Estrogen-related receptor gamma ESRRG 0.0006
273 Apoptosis regulator Bcl-2 BCL2 0.0006
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0006
1196 Complement decay-accelerating factor CD55 0.0006
890 Niemann-Pick C1-like protein 1 NPC1L1 0.0006
3126 Poly [ADP-ribose] polymerase 1 PARP1 0.0006
563 Thyroid peroxidase TPO 0.0006
936 Ephrin type-A receptor 2 EPHA2 0.0006
1291 cAMP response element-binding protein CREB1 0.0006
1569 G1/S-specific cyclin-D1 CCND1 0.0006
1525 Heparin-binding growth factor 2 FGF2 0.0006
634 Squalene monooxygenase SQLE 0.0006
7196 Squalene monooxygenase ERG1 0.0006
2808 Chloramphenicol acetyltransferase 3 cat3 0.0005
84 Nuclear receptor 0B1 NR0B1 0.0005
1760 Aminopeptidase N ANPEP 0.0005
6843 Aminopeptidase N pepN 0.0005
1192 Sulfotransferase 1A1 SULT1A1 0.0005
117 Sterol O-acyltransferase 1 SOAT1 0.0005
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0005
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.0005
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.0005
244 Angiotensin-converting enzyme ACE 0.0005
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0005
823 Fibroblast growth factor receptor 2 FGFR2 0.0005
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0005
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0005
2417 Chloramphenicol acetyltransferase cat 0.0005
3278 Chloramphenicol acetyltransferase cat 0.0005
2810 Dr hemagglutinin structural subunit draA 0.0005
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0005
3601 Dihydropteroate synthase 1 folP1 0.0005
3807 Dihydropteroate synthase 1 folP1 0.0005
3808 Dihydropteroate synthase 2 folP2 0.0005
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.0005
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0005
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0005
1714 Mitogen-activated protein kinase 3 MAPK3 0.0005
2236 Casein kinase II subunit alpha CSNK2A1 0.0005
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0005
3913 Glutamic acid decarboxylase GAD65 0.0005
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0004
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0004
476 RAC-alpha serine/threonine-protein kinase AKT1 0.0004
1992 Vitamin D-binding protein GC 0.0004
319 Opioid receptor, sigma 1 OPRS1 0.0004
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0004
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0004
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0004
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0004
4103 Proteasome subunit beta type 2 PSMB2 0.0004
4101 Proteasome subunit beta type 1 PSMB1 0.0004
4102 Proteasome subunit beta type 5 PSMB5 0.0004
1630 Integrin beta-2 ITGB2 0.0004
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0004
935 Proto-oncogene tyrosine-protein kinase Yes YES1 0.0004
1063 Signal transducer and activator of transcription 5B STAT5B 0.0004
2216 Fibroblast growth factor receptor 4 FGFR4 0.0004
735 Alanine aminotransferase 1 GPT 0.0004
3904 Alanine aminotransferase 2 GPT2 0.0004
511 5-hydroxytryptamine 1F receptor HTR1F 0.0004
251 Alcohol dehydrogenase 1A ADH1A 0.0004
174 Sigma 1-type opioid receptor SIGMAR1 0.0004
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.0004
594 Thyroxine-binding globulin SERPINA7 0.0004
934 Proto-oncogene tyrosine-protein kinase Fyn FYN 0.0004
719 Retinoic acid receptor responder protein 1 RARRES1 0.0003
770 Retinoic acid-induced protein 3 GPRC5A 0.0003
820 Glycine receptor subunit alpha-2 GLRA2 0.0003
268 Adenosine A2b receptor ADORA2B 0.0003
6044 Serum paraoxonase/lactonase 3 PON3 0.0003
758 Thyroid hormone receptor alpha THRA 0.0003
444 Alcohol dehydrogenase 1B ADH1B 0.0003
484 Tyrosine-protein kinase ABL2 ABL2 0.0003
2240 Cell division protein kinase 2 CDK2 0.0003
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0003
572 Integrin alpha-L ITGAL 0.0003
5798 Mitogen-activated protein kinase 11 MAPK11 0.0003
199 Monocarboxylate transporter 8 SLC16A2 0.0003
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0003
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0003
291 Nitric-oxide synthase, endothelial NOS3 0.0003
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0003
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0003
569 Retinal dehydrogenase 2 ALDH1A2 0.0003
267 Plasminogen activator inhibitor 1 SERPINE1 0.0003
346 Thyroid hormone receptor beta-1 THRB 0.0003
1275 Estrogen sulfotransferase SULT1E1 0.0003
611 Retinal dehydrogenase 1 ALDH1A1 0.0003
760 Fibroblast growth factor 1 FGF1 0.0003
517 Alcohol dehydrogenase 1C ADH1C 0.0003
1768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit GNG2 0.0003
1268 Neuropeptide S receptor NPSR1 0.0003
1571 G protein-activated inward rectifier potassium channel 1 KCNJ3 0.0003
1581 G protein-activated inward rectifier potassium channel 2 KCNJ6 0.0003
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0003
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0003
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0003
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0003
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0003
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0003
6221 Steroid hormone receptor ERR1 ESRRA 0.0003
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0003
5934 Cytochrome P450 26A1 CYP26A1 0.0003
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0003
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0003
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0003
1039 Histone deacetylase 9 HDAC9 0.0003
6073 Potassium channel subfamily K member 9 KCNK9 0.0003
6072 Potassium channel subfamily K member 3 KCNK3 0.0003
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.0002
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0002
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0002
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0002
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.0002
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0002
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0002
3957 Adenosine deaminase ADA 0.0002
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0002
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0002
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0002
6168 Solute carrier family 22 member 16 SLC22A16 0.0002
162 Retinoic acid receptor gamma-1 RARG 0.0002
6135 Sodium channel subunit beta-4 SCN4B 0.0002
6134 Sodium channel subunit beta-3 SCN3B 0.0002
6132 Sodium channel subunit beta-1 SCN1B 0.0002
6127 Carbonic anhydrase-related protein CA8 0.0002
6128 Carbonic anhydrase-related protein 10 CA10 0.0002
6133 Sodium channel subunit beta-2 SCN2B 0.0002
6129 Carbonic anhydrase-related protein 11 CA11 0.0002
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0002
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0002
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.0002
6130 Carbonic anhydrase 13 CA13 0.0002
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0002
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0002
2207 Rhodopsin RHO 0.0002
76 Nitric-oxide synthase, brain NOS1 0.0002
2981 Phospholipase A2, membrane associated PLA2G2A 0.0002
3007 Carbonic anhydrase 12 CA12 0.0002
4205 Carbonic anhydrase 9 CA9 0.0002
4936 Cytochrome c2 iso-2 Not Available 0.0001
4916 Cyanoglobin glbN 0.0001
4994 Hemoglobin-like protein HbO glbO 0.0001
4915 Cytochrome c-550 psbV 0.0001
4959 Cytochrome c-550 psbV 0.0001
5216 Cytochrome c-550 psbV 0.0001
4925 Cytochrome c-type protein SHP shp 0.0001
4904 Cytochrome c family protein GSU1996 0.0001
4943 Cytochrome c6 petJ 0.0001
3116 Bacterioferritin bfr 0.0001
4906 Bacterioferritin bfr 0.0001
4965 Bacterioferritin bfr 0.0001
4954 Soluble cytochrome b558 Not Available 0.0001
4934 Cytochrome c-551 nirM 0.0001
5218 Cytochrome c-551 nirM 0.0001
4905 Cytochrome c2 Not Available 0.0001
4939 Cytochrome c2 cycA 0.0001
4964 Cytochrome c2 cycA 0.0001
4979 Cytochrome c2 cycA 0.0001
6673 Cytochrome c2 cycA 0.0001
4910 Cytoglobin CYGB 0.0001
4984 Neuroglobin NGB 0.0001
4981 Iron-starvation protein PigA pigA 0.0001
4909 CooA protein cooA 0.0001
4998 Hemoglobin-like protein yjbI yjbI 0.0001
4935 Cytochrome c-554 cycA1 0.0001
4947 Bacterial hemoglobin vhb 0.0001
4975 Cytochrome c-556 RPA3973 0.0001
4942 Diheme cytochrome c napB napB 0.0001
4931 Cytochrome P450 167A1 CYP167A1 0.0001
5000 HemO hemO 0.0001
4972 P450cin cinA 0.0001
4960 Putative cytochrome P450-family protein SCO7417 0.0001
4971 Nonaheme cytochrome c hmcA 0.0001
4989 Cytochrome c551 peroxidase ccp 0.0001
5222 Cytochrome c551 peroxidase ccpA 0.0001
4961 Hemophore HasA hasA 0.0001
4976 Apocytochrome f petA 0.0001
6407 Apocytochrome f petA 0.0001
4907 Cytochrome c-L moxG 0.0001
6865 Cytochrome c-L moxG 0.0001
4993 Hydroxylamine oxidoreductase hao1 0.0001
4764 Cytochrome P450 165C4 CYP165C4 0.0001
4926 Heme-based aerotactic transducer hemAT hemAT 0.0001
644 Heme oxygenase 2 HMOX2 0.0001
4982 Heme oxygenase 2 pbsA2 0.0001
4952 Catalase/peroxidase katA 0.0001
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0001
4937 Cytochrome oxidase subunit II rcoxA 0.0001
4903 Methyl-accepting chemotaxis protein Tar4 0.0001
4999 Cytochrome P450 165B3 CYP165B3 0.0001
3093 Catalase HPII katE 0.0001
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0001
4922 Cytochrome c, putative SO_4144 0.0001
4920 Peroxidase/catalase katG 0.0001
4990 PpcA ppcA 0.0001
4948 Cytochrome c-553 Not Available 0.0001
4923 Cytochrome c3 DvMF_2499 0.0001
4945 Cytochrome c3 Not Available 0.0001
4949 Cytochrome c3 DVU_3171 0.0001
4968 Cytochrome c3 cytc3 0.0001
4997 Cytochrome c3 SO_2727 0.0001
5219 Cytochrome c3 cyd 0.0001
2119 Cytochrome b5 CYB5A 0.0001
4902 Nine-heme cytochrome c Ddes_2038 0.0001
3189 High-molecular-weight cytochrome c hmcA 0.0001
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0001
3375 Acidic cytochrome c3 Not Available 0.0001
4988 Sulfite oxidase, mitochondrial SUOX 0.0001
2915 Sensor protein fixL fixL 0.0001
4944 Sensor protein fixL fixL 0.0001
4813 Heme oxygenase hmuO 0.0001
5769 Heme oxygenase Not Available 0.0001
3570 Cytochrome P450 152A1 cypC 0.0001
4385 Cytochrome c' Not Available 0.0001
4967 Cytochrome c' cycA 0.0001
5038 Cytochrome c' Not Available 0.0001
5223 Cytochrome c' cycP 0.0001
4037 Hypothetical protein GPX1 0.0001
4297 Hypothetical protein SP_1951 0.0001
4521 Hypothetical protein BC_2969 0.0001
4540 Hypothetical protein TM_1070 0.0001
4555 Hypothetical protein MT1739 0.0001
4569 Hypothetical protein mshD 0.0001
4578 Hypothetical protein PA3270 0.0001
4747 Hypothetical protein PA3967 0.0001
5177 Hypothetical protein TM_0096 0.0001
5194 Hypothetical protein PA1204 0.0001
5240 Hypothetical protein Rv2991 0.0001
5370 Hypothetical protein TM_1158 0.0001
5710 Hypothetical protein Tb927.5.1360 0.0001
4289 Cytochrome P450 TT_P0059 0.0001
6262 Cytochrome P450 staP 0.0001
4992 Cytochrome c peroxidase Not Available 0.0001
2230 Catalase CAT 0.0001
3249 Catalase katA 0.0001
3625 Catalase katA 0.0001
4539 Catalase katA 0.0001
4941 Catalase katB 0.0001
3670 Soluble cytochrome b562 precursor cybC 0.0001
3411 Cytochrome P450 121 cyp121 0.0001
3291 Cytochrome c-552 cycA 0.0001
4927 Cytochrome c-552 nrfA 0.0001
4938 Cytochrome c-552 cycA 0.0001
4953 Cytochrome c-552 nrfA 0.0001
5217 Cytochrome c-552 cycM 0.0001
2617 Nitric oxide synthase oxygenase nos 0.0001
2701 Nitric oxide synthase oxygenase nos 0.0001
3102 Flavohemoprotein hmp 0.0001
4969 Flavohemoprotein hmp 0.0001
4386 Hemoglobin-like protein HbN glbN 0.0001
3127 Nitrite reductase nirS 0.0001
3284 Nitrite reductase nirS 0.0001
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0001
2972 6-deoxyerythronolide B hydroxylase eryF 0.0001
3221 Cytochrome c4 cc4 0.0001
4608 Putative cytochrome P450 SCO1207 0.0001
4963 Putative cytochrome P450 SCO2884 0.0001
6254 Putative cytochrome P450 SCO6998 0.0001
358 Cystathionine beta-synthase CBS 0
693 Hemoglobin subunit beta HBB 0
6268 Hydroxyacid oxidase 1 HAO1 0
810 Heme oxygenase 1 HMOX1 0
3391 Heme oxygenase 1 pbsA1 0
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