DT-Web

DB01098 - Rosuvastatin


Identification
Name Rosuvastatin
Accession Number DB01098 (APRD00546)
Type small molecule
Description Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reducuase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Rosuvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease.
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 481.538
Groups approved
Monoisotopic Weight 481.168284538
Pharmacology
Indication Used as an adjunct to dietary therapy to treat primary hyperlipidemia (heterozygous familial and nonfamilial), mixed dyslipidemia and hypertriglyceridemia. Also indicated for homozygous familial hypercholesterolemia as an adjunct to other lipid-lowering therapies or when other such therapies are not available. Furthermore, it is used to slow the progression of atherosclerosis and for primary prevention of cardiovascular disease.
Mechanism of action Rosuvastatin is a competitive inhibitor of HMG-CoA reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonate, an early rate-limiting step in cholesterol biosynthesis. Rosuvastatin acts primarily in the liver. Decreased hepatic cholesterol concentrations stimulate the upregulation of hepatic low density lipoprotein (LDL) receptors which increases hepatic uptake of LDL. Rosuvastatin also inhibits hepatic synthesis of very low density lipoprotein (VLDL). The overall effect is a decrease in plasma LDL and VLDL. In vitro and in vivo animal studies also demonstrate that rosuvastatin exerts vasculoprotective effects independent of its lipid-lowering properties. Rosuvastatin exerts an anti-inflammatory effect on rat mesenteric microvascular endothelium by attenuating leukocyte rolling, adherence and transmigration (PMID: 11375257). The drug also modulates nitric oxide synthase (NOS) expression and reduces ischemic-reperfusion injuries in rat hearts (PMID: 15914111). Rosuvastatin increases the bioavailability of nitric oxide (PMID: 11375257, 12031849, 15914111) by upregulating NOS (PMID: 12354446) and by increasing the stability of NOS through post-transcriptional polyadenylation (PMID: 17916773). It is unclear as to how rosuvastatin brings about these effects though they may be due to decreased concentrations of mevalonic acid.
Absorption Bioavailability is approximately 20%. Peak plasma concentrations were reached 3 to 5 hours following oral dosing. Both Cmax and AUC increased in approximate proportion to CRESTOR dose. Food has no effect on the AUC of rosuvastatin.
Protein binding 88% bound to plasma proteins (mostly albumin). Binding is reversible and independent of plasma concentrations.
Biotransformation Not extensively metabolized. Only ~10% is excreted as metabolite. Cytochrome P450 (CYP) 2C9 is primarily responsible for the formation of rosuvastatin's major metabolite, N-desmethylrosuvastatin. N-desmethylrosuvastatin has approximately 50% of the pharmacological activity of its parent compound in vitro. Rosuvastatin clearance is not dependent on metabolism by cytochrome P450 3A4 to a clinically significant extent. Rosuvastatin accounts for greater than 90% of the pharmacologic action. Inhibitors of CYP2C9 increase the AUC by less than 2-fold. This interaction does not appear to be clinically significant.
Route of elimination Rosuvastatin is not extensively metabolized; approximately 10% of a radiolabeled dose is recovered as metabolite. Following oral administration, rosuvastatin and its metabolites are primarily excreted in the feces (90%). After an intravenous dose, approximately 28% of total body clearance was via the renal route, and 72% by the hepatic route.
Toxicity Generally well-tolerated. Side effects may include myalgia, constipation, asthenia, abdominal pain, and nausea. Other possible side effects include myotoxicity (myopathy, myositis, rhabdomyolysis) and hepatotoxicity. To avoid toxicity in Asian patients, lower doses should be considered. Pharmacokinetic studies show an approximately two-fold increase in peak plasma concentration and AUC in Asian patients (Philippino, Chinese, Japanese, Korean, Vietnamese, or Asian-Indian descent) compared to Caucasians patients.
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions
Drug Mechanism of interaction
Colchicine Increased risk of rhabdomyolysis with this combination
Cyclosporine Cyclosporine may increase the serum concentration of rosuvastatin. Limit rosuvastatin dosing to 5 mg/day and monitor for changes in the therapeutic and adverse effects of rosuvastatin if cyclosporine is initiated, discontinued or dose changed.
Fenofibrate May cause additive myotoxicity. Monitor for symptoms of muscle toxicity during concomitant therapy.
Gemfibrozil Gemfibrozil may increase the therapeutic and toxic effects of rosuvastatin. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of rosuvastatin if gemfibrozil is initiated, discontinued or dose changed.
Magnesium Magnesium-containing antacids may decrease the absorption of rosuvastatin.
Tipranavir Concomitant therapy of Rosuvastatin and Tipranavir/Ritonavir may increase Rosuvastatin and Tipranavir concentrations. Consider alternate therapy.
Food Interactions Not Available

Targets


3-hydroxy-3-methylglutaryl-coenzyme A reductase
Name 3-hydroxy-3-methylglutaryl-coenzyme A reductase
Gene Name HMGCR
Pharmacological action yes
Actions inhibitor
References
  • Carbonell T, Freire E: Binding thermodynamics of statins to HMG-CoA reductase. Biochemistry. 2005 Sep 6;44(35):11741-8. - Pubmed
  • Chapman MJ, Caslake M, Packard C, McTaggart F: New dimension of statin action on ApoB atherogenicity. Clin Cardiol. 2003 Jan;26(1 Suppl 1):I7-10. - Pubmed
  • Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. - Pubmed
  • Davidson MH: Rosuvastatin: a highly efficacious statin for the treatment of dyslipidaemia. Expert Opin Investig Drugs. 2002 Jan;11(1):125-41. - Pubmed
  • Hanefeld M: Clinical rationale for rosuvastatin, a potent new HMG-CoA reductase inhibitor. Int J Clin Pract. 2001 Jul-Aug;55(6):399-405. - Pubmed
  • Holdgate GA, Ward WH, McTaggart F: Molecular mechanism for inhibition of 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase by rosuvastatin. Biochem Soc Trans. 2003 Jun;31(Pt 3):528-31. - Pubmed
  • McTaggart F, Buckett L, Davidson R, Holdgate G, McCormick A, Schneck D, Smith G, Warwick M: Preclinical and clinical pharmacology of Rosuvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor. Am J Cardiol. 2001 Mar 8;87(5A):28B-32B. - Pubmed
  • Olsson AG, McTaggart F, Raza A: Rosuvastatin: a highly effective new HMG-CoA reductase inhibitor. Cardiovasc Drug Rev. 2002 Winter;20(4):303-28. - Pubmed
DTHybrid score 0.4247

Enzymes


Cytochrome P450 2C9
Name Cytochrome P450 2C9
Gene Name CYP2C9
Actions substrate,inhibitor
References
  • Olsson AG, McTaggart F, Raza A: Rosuvastatin: a highly effective new HMG-CoA reductase inhibitor. Cardiovasc Drug Rev. 2002 Winter;20(4):303-28. - Pubmed
  • Neuvonen PJ, Niemi M, Backman JT: Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance. Clin Pharmacol Ther. 2006 Dec;80(6):565-81. - Pubmed
  • Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. - Pubmed
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.5714
Cytochrome P450 2C19
Name Cytochrome P450 2C19
Gene Name CYP2C19
Actions substrate
References
  • Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. - Pubmed
DTHybrid score 0.4739
Cytochrome P450 3A4
Name Cytochrome P450 3A4
Gene Name CYP3A4
Actions substrate,inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.7581
Cytochrome P450 3A5
Name Cytochrome P450 3A5
Gene Name CYP3A5
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.4356

Transporters


Multidrug resistance-associated protein 1
Name Multidrug resistance-associated protein 1
Gene Name ABCC1
Actions substrate
References
  • Knauer MJ, Urquhart BL, Meyer zu Schwabedissen HE, Schwarz UI, Lemke CJ, Leake BF, Kim RB, Tirona RG: Human skeletal muscle drug transporters determine local exposure and toxicity of statins. Circ Res. 2010 Feb 5;106(2):297-306. Epub 2009 Nov 25. - Pubmed
DTHybrid score 0.3272
Multidrug resistance-associated protein 4
Name Multidrug resistance-associated protein 4
Gene Name ABCC4
Actions substrate
References
  • Knauer MJ, Urquhart BL, Meyer zu Schwabedissen HE, Schwarz UI, Lemke CJ, Leake BF, Kim RB, Tirona RG: Human skeletal muscle drug transporters determine local exposure and toxicity of statins. Circ Res. 2010 Feb 5;106(2):297-306. Epub 2009 Nov 25. - Pubmed
DTHybrid score 0.2563
Solute carrier organic anion transporter family member 1A2
Name Solute carrier organic anion transporter family member 1A2
Gene Name SLCO1A2
Actions Not Available
References
  • Ho RH, Tirona RG, Leake BF, Glaeser H, Lee W, Lemke CJ, Wang Y, Kim RB: Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics. Gastroenterology. 2006 May;130(6):1793-806. Epub 2006 Mar 6. - Pubmed
DTHybrid score 0.4487
Solute carrier organic anion transporter family member 1B1
Name Solute carrier organic anion transporter family member 1B1
Gene Name SLCO1B1
Actions substrate
References
  • van de Steeg E, Greupink R, Schreurs M, Nooijen IH, Verhoeckx KC, Hanemaaijer R, Ripken D, Monshouwer M, Vlaming ML, DeGroot J, Verwei M, Russel FG, Huisman MT, Wortelboer HM: Drug-drug interactions between rosuvastatin and oral antidiabetic drugs occurring at the level of OATP1B1. Drug Metab Dispos. 2013 Mar;41(3):592-601. doi: 10.1124/dmd.112.049023. Epub 2012 Dec 17. - Pubmed
DTHybrid score 0.4715
Solute carrier organic anion transporter family member 1B3
Name Solute carrier organic anion transporter family member 1B3
Gene Name SLCO1B3
Actions Not Available
References
  • Ho RH, Tirona RG, Leake BF, Glaeser H, Lee W, Lemke CJ, Wang Y, Kim RB: Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics. Gastroenterology. 2006 May;130(6):1793-806. Epub 2006 Mar 6. - Pubmed
DTHybrid score 0.35
Solute carrier organic anion transporter family member 2B1
Name Solute carrier organic anion transporter family member 2B1
Gene Name SLCO2B1
Actions Not Available
References
  • Ho RH, Tirona RG, Leake BF, Glaeser H, Lee W, Lemke CJ, Wang Y, Kim RB: Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics. Gastroenterology. 2006 May;130(6):1793-806. Epub 2006 Mar 6. - Pubmed
DTHybrid score 0.3328
Cystine/glutamate transporter
Name Cystine/glutamate transporter
Gene Name SLC7A11
Actions Not Available
References
  • Ho RH, Tirona RG, Leake BF, Glaeser H, Lee W, Lemke CJ, Wang Y, Kim RB: Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics. Gastroenterology. 2006 May;130(6):1793-806. Epub 2006 Mar 6. - Pubmed
DTHybrid score 0.2928
Bile salt export pump
Name Bile salt export pump
Gene Name ABCB11
Actions substrate
References
  • Jemnitz K, Veres Z, Tugyi R, Vereczkey L: Biliary efflux transporters involved in the clearance of rosuvastatin in sandwich culture of primary rat hepatocytes. Toxicol In Vitro. 2010 Mar;24(2):605-10. doi: 10.1016/j.tiv.2009.10.009. Epub 2009 Oct 21. - Pubmed
DTHybrid score 0.2583
ATP-binding cassette sub-family G member 2
Name ATP-binding cassette sub-family G member 2
Gene Name ABCG2
Actions substrate
References
  • FDA label -
DTHybrid score 0.4292

Carriers


Multidrug resistance-associated protein 1
Name Multidrug resistance-associated protein 1
Gene Name ABCC1
Actions
References Not Available
DTHybrid score 0.3272
Multidrug resistance-associated protein 4
Name Multidrug resistance-associated protein 4
Gene Name ABCC4
Actions
References Not Available
DTHybrid score 0.2563
Solute carrier organic anion transporter family member 1A2
Name Solute carrier organic anion transporter family member 1A2
Gene Name SLCO1A2
Actions
References Not Available
DTHybrid score 0.4487
Solute carrier organic anion transporter family member 1B1
Name Solute carrier organic anion transporter family member 1B1
Gene Name SLCO1B1
Actions
References Not Available
DTHybrid score 0.4715
Solute carrier organic anion transporter family member 1B3
Name Solute carrier organic anion transporter family member 1B3
Gene Name SLCO1B3
Actions
References Not Available
DTHybrid score 0.35
Solute carrier organic anion transporter family member 2B1
Name Solute carrier organic anion transporter family member 2B1
Gene Name SLCO2B1
Actions
References Not Available
DTHybrid score 0.3328
Cystine/glutamate transporter
Name Cystine/glutamate transporter
Gene Name SLC7A11
Actions
References Not Available
DTHybrid score 0.2928
Bile salt export pump
Name Bile salt export pump
Gene Name ABCB11
Actions
References Not Available
DTHybrid score 0.2583
ATP-binding cassette sub-family G member 2
Name ATP-binding cassette sub-family G member 2
Gene Name ABCG2
Actions
References Not Available
DTHybrid score 0.4292

Predictions


Id Partner name Gene Name Score
1588 Multidrug resistance protein 1 ABCB1 0.4943
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.4247
4924 Cytochrome P450 2C8 CYP2C8 0.3735
4119 Cytochrome P450 2D6 CYP2D6 0.3283
4200 Cytochrome P450 1A2 CYP1A2 0.2975
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.2931
6107 Cytochrome P450 3A7 CYP3A7 0.2604
6030 Cytochrome P450 2B6 CYP2B6 0.2033
1729 Solute carrier family 22 member 6 SLC22A6 0.1856
6142 Solute carrier family 22 member 8 SLC22A8 0.1811
6024 Cytochrome P450 1A1 CYP1A1 0.155
6013 Cytochrome P450 2E1 CYP2E1 0.1482
20 Prostaglandin G/H synthase 1 PTGS1 0.1386
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.1307
6141 Sodium/bile acid cotransporter SLC10A1 0.1286
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.1158
6145 Solute carrier family 22 member 1 SLC22A1 0.1145
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.107
1181 Alpha-1-acid glycoprotein 1 ORM1 0.1062
6143 Solute carrier family 22 member 7 SLC22A7 0.1003
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0974
5718 Cytochrome P450 2A6 CYP2A6 0.0957
1024 Solute carrier family 22 member 11 SLC22A11 0.0956
290 Prostaglandin G/H synthase 2 PTGS2 0.0933
738 Monocarboxylate transporter 1 SLC16A1 0.0903
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0856
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0817
6148 Multidrug resistance-associated protein 7 ABCC10 0.0807
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0784
1898 Cytochrome P450 1B1 CYP1B1 0.0775
6136 Multidrug resistance-associated protein 5 ABCC5 0.0774
4604 Liver carboxylesterase 1 CES1 0.0729
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0712
6144 Solute carrier family 22 member 2 SLC22A2 0.0687
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0665
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0663
3587 Gastrotropin FABP6 0.0662
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0615
6106 Cytochrome P450 2C18 CYP2C18 0.0611
136 Estrogen receptor ESR1 0.0595
238 Peroxisome proliferator-activated receptor gamma PPARG 0.058
731 HIV-1 protease HIV-1 protease 0.0567
118 Organic cation/carnitine transporter 2 SLC22A5 0.0551
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0542
492 Histamine H1 receptor HRH1 0.054
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0536
6167 Organic solute transporter subunit beta OSTB 0.0528
6166 Organic solute transporter subunit alpha OSTA 0.0527
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0523
3811 Cytochrome P450 19A1 CYP19A1 0.0521
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0521
6137 Multidrug resistance-associated protein 6 ABCC6 0.0512
70 Type-1 angiotensin II receptor AGTR1 0.051
817 DNA topoisomerase 2-alpha TOP2A 0.0487
3998 B(0,+)-type amino acid transporter 1 SLC7A9 0.0487
38 Cystinosin CTNS 0.0485
1963 Neutral and basic amino acid transport protein rBAT SLC3A1 0.0485
6147 Solute carrier family 22 member 3 SLC22A3 0.0431
4589 3-hydroxy-3-methylglutaryl CoA synthase mvaS 0.0417
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0412
6151 Monocarboxylate transporter 10 SLC16A10 0.041
824 Sodium-dependent serotonin transporter SLC6A4 0.0397
871 Glucocorticoid receptor NR3C1 0.0397
320 5-hydroxytryptamine 1A receptor HTR1A 0.0396
468 Cytochrome P450 4A11 CYP4A11 0.0387
29 Tubulin beta-1 chain TUBB1 0.0364
6031 Cytochrome P450 3A43 CYP3A43 0.0353
556 Alpha-1A adrenergic receptor ADRA1A 0.0343
891 Dihydropteroate synthase folP 0.034
5359 Dihydropteroate synthase folP 0.034
7175 Dihydropteroate synthase sulI 0.034
1650 Heme carrier protein 1 SLC46A1 0.0339
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0339
6599 HTH-type transcriptional regulator ttgR ttgR 0.0335
833 Organic cation/carnitine transporter 1 SLC22A4 0.0333
275 Arachidonate 5-lipoxygenase ALOX5 0.0331
502 5-hydroxytryptamine 2A receptor HTR2A 0.0328
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0317
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0316
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0313
844 Epidermal growth factor receptor EGFR 0.0312
373 Transthyretin TTR 0.0305
756 Sex hormone-binding globulin SHBG 0.0295
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0292
758 Thyroid hormone receptor alpha THRA 0.029
831 D(2) dopamine receptor DRD2 0.0287
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0284
6220 Aryl hydrocarbon receptor AHR 0.0282
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.0282
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0281
6085 Fatty acid-binding protein, intestinal FABP2 0.028
504 Mast/stem cell growth factor receptor KIT 0.0276
2539 Tubulin alpha-1 chain TUBA4A 0.0274
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0271
594 Thyroxine-binding globulin SERPINA7 0.027
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0264
847 Mu-type opioid receptor OPRM1 0.0263
78 Acetyl-CoA acetyltransferase, mitochondrial ACAT1 0.0262
260 Cytochrome P450 51 ERG11 0.0261
761 Cytochrome P450 51 ERG11 0.0261
3163 Cytochrome P450 51 cyp51 0.0261
346 Thyroid hormone receptor beta-1 THRB 0.026
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0259
273 Apoptosis regulator Bcl-2 BCL2 0.0257
869 Estrogen receptor beta ESR2 0.0249
318 Alpha-2A adrenergic receptor ADRA2A 0.0247
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0247
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0246
6149 Solute carrier family 22 member 10 SLC22A10 0.0244
407 Vascular endothelial growth factor receptor 2 KDR 0.0244
3671 7-alpha-hydroxysteroid dehydrogenase hdhA 0.0242
632 Alpha-1B adrenergic receptor ADRA1B 0.024
26 Vascular endothelial growth factor receptor 3 FLT4 0.0238
341 5-hydroxytryptamine 3 receptor HTR3A 0.0237
87 Hypoxanthine-guanine phosphoribosyltransferase HPRT1 0.0236
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0235
146 Androgen receptor AR 0.0234
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0231
23 D(1A) dopamine receptor DRD1 0.0231
380 Cytochrome P450 17A1 CYP17A1 0.0229
32 Vascular endothelial growth factor receptor 1 FLT1 0.0228
161 Tubulin beta chain TUBB 0.0226
312 Tubulin beta chain TUB2 0.0226
904 Glutathione S-transferase P GSTP1 0.0218
3941 Amine oxidase [flavin-containing] A MAOA 0.0215
406 Prostaglandin E2 receptor, EP2 subtype PTGER2 0.0213
467 Delta-type opioid receptor OPRD1 0.0213
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0212
24 Thymidylate synthase TMP1 0.0211
359 Thymidylate synthase TYMS 0.0211
2626 Thymidylate synthase thyA 0.0211
2729 Thymidylate synthase thyA 0.0211
5352 Thymidylate synthase THYA 0.0211
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.021
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0209
228 Beta platelet-derived growth factor receptor PDGFRB 0.0209
49 Endothelin B receptor EDNRB 0.0209
614 Progesterone receptor PGR 0.0207
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0207
696 Kappa-type opioid receptor OPRK1 0.0204
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0204
5923 Microtubule-associated protein tau MAPT 0.0204
5924 Microtubule-associated protein 4 MAP4 0.0204
952 Dipeptidyl peptidase 4 DPP4 0.0203
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0202
1353 DNA topoisomerase 1 TOP1 0.0202
3552 DNA topoisomerase 1 topA 0.0202
713 Sodium-dependent dopamine transporter SLC6A3 0.0202
2404 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PIK3CG 0.0201
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0198
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.0198
1852 Microtubule-associated protein 2 MAP2 0.0198
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0198
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0197
578 Endothelin-1 receptor EDNRA 0.0197
737 Mineralocorticoid receptor NR3C2 0.0196
6339 Ig kappa chain V-II region RPMI 6410 Not Available 0.0196
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0195
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0195
4120 NADPH--cytochrome P450 reductase POR 0.0195
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0194
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0193
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0188
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0188
122 P2Y purinoceptor 12 P2RY12 0.0188
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0187
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0187
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0186
3947 Xanthine dehydrogenase/oxidase XDH 0.0185
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0184
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0183
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0179
3923 Cholinesterase BCHE 0.0179
6182 Cytochrome P450 2J2 CYP2J2 0.0177
5626 Nucleoside diphosphate kinase B NME2 0.0175
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0175
885 5-hydroxytryptamine 1B receptor HTR1B 0.0174
683 Potassium transporter GK0582 0.0174
590 5-hydroxytryptamine 2C receptor HTR2C 0.0173
672 Prostaglandin F2-alpha receptor PTGFR 0.0171
1389 Transforming growth factor beta-1 TGFB1 0.0169
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0168
183 Vascular endothelial growth factor A VEGFA 0.0168
232 Corticosteroid-binding globulin SERPINA6 0.0166
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0165
766 Beta-2 adrenergic receptor ADRB2 0.0162
725 5-hydroxytryptamine 1D receptor HTR1D 0.0159
489 Monocarboxylate transporter 2 SLC16A7 0.0159
6020 Aldehyde oxidase AOX1 0.0159
80 Peroxisome proliferator-activated receptor alpha PPARA 0.0157
3917 Methylenetetrahydrofolate reductase MTHFR 0.0157
705 Glutamate receptor 1 GRIA1 0.0156
887 DNA gyrase subunit B gyrB 0.0156
4150 DNA gyrase subunit B gyrB 0.0156
6225 DNA gyrase subunit B gyrB 0.0156
293 Gamma-glutamyl hydrolase GGH 0.0156
5787 Angiopoietin-1 receptor TEK 0.0156
3810 Catechol O-methyltransferase COMT 0.0155
165 FL cytokine receptor FLT3 0.0155
1630 Integrin beta-2 ITGB2 0.0155
199 Monocarboxylate transporter 8 SLC16A2 0.0154
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0153
2808 Chloramphenicol acetyltransferase 3 cat3 0.0152
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0151
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.015
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.015
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.015
102 DNA topoisomerase I, mitochondrial TOP1MT 0.015
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0149
4773 Deoxycytidine kinase DCK 0.0149
5294 Nucleoside diphosphate kinase A NME1 0.0148
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0147
3809 Estrogen-related receptor gamma ESRRG 0.0145
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0143
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0143
6541 Peptostreptococcal albumin-binding protein pab 0.0142
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.0142
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0141
284 DNA-directed RNA polymerase beta chain rpoB 0.0138
5773 DNA-directed RNA polymerase beta chain rpoB 0.0138
1792 Tissue-type plasminogen activator PLAT 0.0137
789 Alpha-1D adrenergic receptor ADRA1D 0.0137
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0136
811 Translocator protein TSPO 0.0134
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0133
4148 Serine/threonine-protein kinase mTOR MTOR 0.0131
3307 Acriflavine resistance protein B acrB 0.013
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0129
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0129
244 Angiotensin-converting enzyme ACE 0.0129
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0128
365 Dihydrofolate reductase DHFR 0.0127
2381 Dihydrofolate reductase DFR1 0.0127
2833 Dihydrofolate reductase Not Available 0.0127
2931 Dihydrofolate reductase folA 0.0127
3544 Dihydrofolate reductase folA 0.0127
3682 Dihydrofolate reductase folA 0.0127
6642 Dihydrofolate reductase folA 0.0127
6756 Dihydrofolate reductase dfrA 0.0127
117 Sterol O-acyltransferase 1 SOAT1 0.0126
638 D(3) dopamine receptor DRD3 0.0126
469 Annexin A1 ANXA1 0.0124
6044 Serum paraoxonase/lactonase 3 PON3 0.0123
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0122
4122 Histone deacetylase 2 HDAC2 0.0119
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0119
3270 Elongation factor G fusA 0.0119
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0119
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0119
2331 HTH-type transcriptional regulator qacR qacR 0.0118
6461 HTH-type transcriptional regulator qacR qacR 0.0118
2021 Thrombomodulin THBD 0.0118
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.0117
992 Protein tyrosine kinase 2 beta PTK2B 0.0117
723 Cytosolic phospholipase A2 PLA2G4A 0.0117
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0117
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0116
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0116
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0116
4237 50S ribosomal protein L22 rplV 0.0116
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0115
572 Integrin alpha-L ITGAL 0.0115
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0114
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0113
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.0113
6033 High affinity interleukin-8 receptor A CXCR1 0.0112
4192 DNA topoisomerase 2-beta TOP2B 0.0111
500 Monocarboxylate transporter 4 SLC16A3 0.0111
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.011
3939 Amine oxidase [flavin-containing] B MAOB 0.011
511 5-hydroxytryptamine 1F receptor HTR1F 0.011
629 Alpha-2B adrenergic receptor ADRA2B 0.0109
465 Calmodulin CALM1 0.0108
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0108
1757 Myeloperoxidase MPO 0.0108
6043 Putative G-protein coupled receptor 44 GPR44 0.0107
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0106
645 Penicillin-binding protein 1A mrcA 0.0106
5805 Penicillin-binding protein 1A ponA 0.0106
6185 Penicillin-binding protein 1A mrcA 0.0106
6799 Penicillin-binding protein 1A pbpA 0.0106
4238 50S ribosomal protein L4 rplD 0.0106
5578 50S ribosomal protein L4 rplD 0.0106
6173 50S ribosomal protein L4 rplD 0.0106
6219 50S ribosomal protein L4 rplD 0.0106
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0106
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0105
2391 Ferrochelatase hemH 0.0104
6502 Ferrochelatase DKFZp686P18130 0.0104
1591 Ferrochelatase, mitochondrial FECH 0.0104
3856 Fibroblast growth factor receptor 3 FGFR3 0.0104
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0104
1010 Cytochrome P450 51A1 CYP51A1 0.0104
5818 Folate receptor alpha FOLR1 0.0104
482 Glycine receptor subunit alpha-1 GLRA1 0.0103
124 Histamine H2 receptor HRH2 0.0102
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0101
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0101
543 Penicillin-binding protein 1B mrcB 0.0101
6186 Penicillin-binding protein 1B ponB 0.0101
6822 Penicillin-binding protein 1b pbp1b 0.0101
6844 Penicillin-binding protein 1b pbp1b 0.0101
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.01
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.01
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.01
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.01
193 Beta-1 adrenergic receptor ADRB1 0.01
477 DNA topoisomerase 4 subunit A parC 0.01
886 DNA topoisomerase 4 subunit A parC 0.01
6226 DNA topoisomerase 4 subunit A parC 0.01
1 Peptidoglycan synthetase ftsI ftsI 0.0099
4155 Peptidoglycan synthetase ftsI ftsI 0.0099
823 Fibroblast growth factor receptor 2 FGFR2 0.0099
768 FK506-binding protein 1A FKBP1A 0.0099
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0099
378 Alpha-2C adrenergic receptor ADRA2C 0.0098
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0098
2211 Fatty acid-binding protein, heart FABP3 0.0098
404 DNA gyrase subunit A gyrA 0.0098
6224 DNA gyrase subunit A gyrA 0.0098
5650 NimA-related protein DR_0842 0.0098
6501 Fatty acid-binding protein, liver FABP1 0.0098
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0097
527 Prostacyclin receptor PTGIR 0.0097
1119 Peroxiredoxin-5, mitochondrial PRDX5 0.0097
1648 Elastin ELN 0.0096
777 Tumor necrosis factor TNF 0.0095
6058 Geranylgeranyl pyrophosphate synthetase GGPS1 0.0095
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.0095
566 Serotransferrin TF 0.0094
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0094
908 Glutathione S-transferase theta-1 GSTT1 0.0094
596 3-oxo-5-alpha-steroid 4-dehydrogenase 1 SRD5A1 0.0094
558 Solute carrier family 12 member 1 SLC12A1 0.0094
6102 Arylamine N-acetyltransferase 2 NAT2 0.0094
2981 Phospholipase A2, membrane associated PLA2G2A 0.0094
259 Microsomal triglyceride transfer protein large subunit MTTP 0.0093
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0093
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0093
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0093
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0093
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0093
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0093
853 Farnesyl pyrophosphate synthetase FDPS 0.0092
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0092
588 Chromodomain-helicase-DNA-binding protein 1 CHD1 0.0091
750 Voltage-dependent calcium channel gamma-1 subunit CACNG1 0.0091
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0091
1405 Thiopurine S-methyltransferase TPMT 0.009
6495 Cytochrome c oxidase subunit 7C, mitochondrial COX7C 0.009
592 Carbonic anhydrase 4 CA4 0.009
6493 Cytochrome c oxidase subunit 6C COX6C 0.009
6494 Cytochrome c oxidase subunit 7B, mitochondrial COX7B 0.009
6496 Cytochrome c oxidase subunit 8A, mitochondrial COX8A 0.009
6499 Cytochrome c oxidase polypeptide 7A1, mitochondrial COX7A1 0.009
6497 Cytochrome c oxidase subunit 6A2, mitochondrial COX6A2 0.009
6498 Cytochrome c oxidase subunit 6B1 COX6B1 0.009
6491 Cytochrome c oxidase subunit 5A, mitochondrial COX5A 0.009
6489 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial COX4I1 0.009
5793 Cytochrome c oxidase subunit 2 MT-CO2 0.009
6559 Cytochrome c oxidase subunit 2 ctaC 0.009
6669 Cytochrome c oxidase subunit 2 ctaC 0.009
6490 Cytochrome c oxidase subunit 3 MT-CO3 0.009
371 Cytochrome c oxidase subunit 1 MT-CO1 0.009
6558 Cytochrome c oxidase subunit 1 ctaD 0.009
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.009
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0089
6014 Cytochrome P450 2A13 CYP2A13 0.0089
1656 CYP2B protein CYP2B 0.0089
3317 Holo-[acyl-carrier-protein] synthase acpS 0.0088
4381 Holo-[acyl-carrier-protein] synthase acpS 0.0088
3125 Protease synthase and sporulation negative regulatory protein PAI 1 paiA 0.0088
818 50S ribosomal protein L10 rplJ 0.0087
432 D(4) dopamine receptor DRD4 0.0087
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0087
6837 Serine/threonine-protein kinase 17B STK17B 0.0086
241 Calcium-transporting ATPase type 2C member 1 ATP2C1 0.0086
6836 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial HIBCH 0.0086
921 Glutamate receptor 2 GRIA2 0.0086
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0086
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0086
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0086
1629 Transcription factor AP-1 JUN 0.0085
461 Glycine receptor subunit alpha-3 GLRA3 0.0085
68 Cannabinoid receptor 1 CNR1 0.0084
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0084
1050 Bile salt sulfotransferase SULT2A1 0.0084
642 3-oxo-5-alpha-steroid 4-dehydrogenase 2 SRD5A2 0.0083
2540 Choloylglycine hydrolase cbh 0.0083
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0083
6212 Tubulin gamma-1 chain TUBG1 0.0082
6210 Tubulin delta chain TUBD1 0.0082
6211 Tubulin epsilon chain TUBE1 0.0082
537 ATP synthase delta chain, mitochondrial ATP5D 0.0082
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0081
5880 Thrombopoietin receptor MPL 0.0081
131 Synaptic vesicular amine transporter SLC18A2 0.008
1141 Sialidase-1 NEU1 0.008
64 Neuraminidase NA 0.008
641 Neuraminidase NA 0.008
2676 Neuraminidase NA 0.008
3026 Neuraminidase NA 0.008
3519 Neuraminidase NA 0.008
6007 Neuraminidase NA 0.008
4217 Telomerase reverse transcriptase TERT 0.008
6525 Group IID secretory phospholipase A2 PLA2G2D 0.008
2636 Shikimate dehydrogenase aroE 0.0079
3515 Shikimate dehydrogenase aroE 0.0079
427 Substance-P receptor TACR1 0.0079
3254 Bifunctional protein putA [Includes: Proline dehydrogenase putA 0.0079
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0079
295 Carbonic anhydrase 1 CA1 0.0078
860 Nicotinamide N-methyltransferase NNMT 0.0078
583 Nicotinate-nucleotide pyrophosphorylase [carboxylating] QPRT 0.0078
2442 Nicotinate-nucleotide pyrophosphorylase [carboxylating] nadC 0.0078
2459 Nicotinate-nucleotide pyrophosphorylase [carboxylating] nadC 0.0078
699 Nicotinic acid receptor 1 GPR109A 0.0078
928 Nicotinic acid receptor 2 GPR109B 0.0078
442 Envelope glycoprotein gp41 0.0078
4859 Envelope glycoprotein env 0.0078
84 Nuclear receptor 0B1 NR0B1 0.0077
1517 Beta-3 adrenergic receptor ADRB3 0.0077
2449 Tubulin alpha-3 chain TUBA1A 0.0077
3932 Glutathione S-transferase A2 GSTA2 0.0077
357 Carbonic anhydrase 2 CA2 0.0077
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0077
1618 High affinity nerve growth factor receptor NTRK1 0.0076
5934 Cytochrome P450 26A1 CYP26A1 0.0076
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0076
718 Folate receptor gamma FOLR3 0.0075
299 Folate receptor beta FOLR2 0.0075
804 Mitochondrial folate transporter/carrier SLC25A32 0.0075
6656 UDP-glucuronosyltransferase 3A1 UGT3A1 0.0075
517 Alcohol dehydrogenase 1C ADH1C 0.0075
6002 Prostaglandin E2 receptor EP4 subtype PTGER4 0.0075
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0075
1525 Heparin-binding growth factor 2 FGF2 0.0075
115 Penicillin-binding protein 2 mrdA 0.0075
6069 Penicillin-binding protein 2 mrdA 0.0075
6118 Penicillin-binding protein 2 penA 0.0075
6187 Penicillin-binding protein 2 pbpA 0.0075
6686 Penicillin-binding protein 2 pbp2 0.0075
6939 Penicillin-binding protein 2 mrdA 0.0075
7163 Penicillin-binding protein 2 pbpA 0.0075
603 DNA polymerase alpha catalytic subunit POLA1 0.0074
6218 Pannexin-1 PANX1 0.0074
7 Nitric oxide synthase, inducible NOS2 0.0074
716 5-hydroxytryptamine 7 receptor HTR7 0.0074
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0073
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.0072
4116 Dihydropteroate synthetase Not Available 0.0072
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0072
2599 Tyrosine-protein kinase HCK HCK 0.0072
606 Cytochrome P450 27, mitochondrial CYP27A1 0.0072
702 UMP-CMP kinase CMPK1 0.0072
6168 Solute carrier family 22 member 16 SLC22A16 0.0072
342 P protein [Includes: DNA-directed DNA polymerase P 0.0072
612 P protein [Includes: DNA-directed DNA polymerase P 0.0072
909 Maleylacetoacetate isomerase GSTZ1 0.0071
571 Melatonin receptor type 1A MTNR1A 0.007
362 Melatonin receptor type 1B MTNR1B 0.007
360 Ribonucleoside-diphosphate reductase large subunit RRM1 0.007
239 Coagulation factor X F10 0.007
677 Choline-phosphate cytidylyltransferase A PCYT1A 0.007
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.007
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0069
4131 Prostaglandin E2 receptor, EP3 subtype PTGER3 0.0069
2853 14 kDa fatty acid-binding protein Not Available 0.0068
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0068
5300 Antigen peptide transporter 1 TAP1 0.0068
5599 3-carboxy-cis,cis-muconate cycloisomerase pcaB 0.0068
4226 Uridine phosphorylase 2 UPP2 0.0067
890 Niemann-Pick C1-like protein 1 NPC1L1 0.0067
436 5-hydroxytryptamine 2B receptor HTR2B 0.0067
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.0067
563 Thyroid peroxidase TPO 0.0067
36 Insulin receptor INSR 0.0066
267 Plasminogen activator inhibitor 1 SERPINE1 0.0066
611 Retinal dehydrogenase 1 ALDH1A1 0.0066
5669 50S ribosomal protein L27 rpmA 0.0066
5675 Chaperone protein torD torD 0.0065
5670 Organic hydroperoxide resistance protein ohr 0.0065
5672 Molybdenum cofactor biosynthesis protein A moaA 0.0065
5410 Unsaturated glucuronyl hydrolase ugl 0.0065
5676 Axin-1 AXIN1 0.0065
5673 C protein alpha-antigen bca 0.0065
2216 Fibroblast growth factor receptor 4 FGFR4 0.0065
1313 Lactoylglutathione lyase GLO1 0.0065
1198 Serum paraoxonase/arylesterase 1 PON1 0.0065
6223 Penicillin-binding protein 1C pbpC 0.0065
6500 Phospholipase A2 PLA2G1B 0.0064
6042 Prostaglandin reductase 2 PTGR2 0.0064
133 Dihydropterate synthase sulI 0.0063
54 Prothrombin F2 0.0062
5482 Sialidase-2 NEU2 0.0062
2320 Thymidine kinase, cytosolic TK1 0.0062
459 Retinoic acid receptor RXR-alpha RXRA 0.0062
6138 Multidrug resistance protein 3 ABCB4 0.0062
4225 Uridine phosphorylase 1 UPP1 0.0062
6344 ATP synthase subunit gamma, mitochondrial ATP5C1 0.0062
6342 ATP synthase subunit alpha, mitochondrial ATP5A1 0.0062
6343 ATP synthase subunit beta, mitochondrial ATP5B 0.0062
3639 Thymidine phosphorylase deoA 0.0062
3936 Thymidine phosphorylase TYMP 0.0062
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0062
3685 Catabolite gene activator crp 0.0061
4655 Adenylate cyclase cyaC 0.0061
4759 Adenylate cyclase cyaB2 0.0061
6146 High affinity copper uptake protein 1 SLC31A1 0.0061
1760 Aminopeptidase N ANPEP 0.0061
6843 Aminopeptidase N pepN 0.0061
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0061
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.006
176 30S ribosomal protein S10 rpsJ 0.006
6175 30S ribosomal protein S10 rpsJ 0.006
751 Potassium channel subfamily K member 6 KCNK6 0.006
4117 Probable pyruvate-flavodoxin oxidoreductase ydbK 0.006
94 5-hydroxytryptamine 4 receptor HTR4 0.006
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.006
6221 Steroid hormone receptor ERR1 ESRRA 0.006
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.006
896 Glutathione S-transferase Mu 1 GSTM1 0.0059
633 Penicillin-binding proteins 1A/1B pbpA 0.0059
6171 Solute carrier family 28 member 3 SLC28A3 0.0059
2285 Streptogramin A acetyltransferase vatD 0.0059
4210 Toll-like receptor 4 TLR4 0.0058
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0058
413 Amidophosphoribosyltransferase PPAT 0.0058
2515 Amidophosphoribosyltransferase purF 0.0058
3714 Amidophosphoribosyltransferase purF 0.0058
2183 Fatty acid-binding protein, adipocyte FABP4 0.0058
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0057
106 Cannabinoid receptor 2 CNR2 0.0057
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0057
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0057
153 Dopamine beta-hydroxylase DBH 0.0057
6579 Calcium/calmodulin-dependent protein kinase type II alpha chain CAMK2A 0.0057
685 Oxygen-insensitive NADPH nitroreductase nfsA 0.0057
6945 Oxygen-insensitive NADPH nitroreductase rdxA 0.0057
6169 ATP-binding cassette sub-family A member 5 ABCA5 0.0056
6824 Tyrosine-protein kinase Lyn LYN 0.0056
780 Retinoic acid receptor RXR-gamma RXRG 0.0056
528 5-hydroxytryptamine 1E receptor HTR1E 0.0056
172 Potassium channel subfamily K member 1 KCNK1 0.0055
620 Bifunctional dihydrofolate reductase-thymidylate synthase Not Available 0.0055
1291 cAMP response element-binding protein CREB1 0.0055
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0055
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0055
6259 (3R)-hydroxymyristoyl-acyl carrier protein dehydratase fabZ 0.0055
1192 Sulfotransferase 1A1 SULT1A1 0.0055
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0054
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0054
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0054
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0054
1256 5-hydroxytryptamine 6 receptor HTR6 0.0053
976 Platelet glycoprotein IX GP9 0.0053
3957 Adenosine deaminase ADA 0.0053
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0053
4811 Amylosucrase ams 0.0053
2280 Listeriolysin regulatory protein prfA 0.0052
3191 Histidinol dehydrogenase hisD 0.0052
551 Carnitine O-acetyltransferase CRAT 0.0052
4084 Peptidyl-prolyl cis-trans isomerase B PPIB 0.0052
191 Peptide methionine sulfoxide reductase MSRA 0.0052
4760 Mll3241 protein mll3241 0.0052
6126 Carbonic anhydrase 7 CA7 0.0052
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0052
88 Retinoic acid receptor RXR-beta RXRB 0.0052
163 D(1B) dopamine receptor DRD5 0.005
4109 cAMP-specific 3',5'-cyclic phosphodiesterase 4C PDE4C 0.005
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.005
6027 Alkaline phosphatase, tissue-nonspecific isozyme ALPL 0.005
5849 cAMP-dependent protein kinase type I-alpha regulatory subunit PRKAR1A 0.0049
814 Ryanodine receptor 1 RYR1 0.0049
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0049
936 Ephrin type-A receptor 2 EPHA2 0.0048
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.0048
6184 D-alanyl-D-alanine carboxypeptidase dacC dacC 0.0048
856 Vitamin D3 receptor VDR 0.0047
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0047
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0047
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0047
4203 Histamine N-methyltransferase HNMT 0.0047
621 Periplasmic [Fe] hydrogenase 1 Not Available 0.0047
2159 Quinone oxidoreductase CRYZ 0.0047
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0046
76 Nitric-oxide synthase, brain NOS1 0.0046
3904 Alanine aminotransferase 2 GPT2 0.0046
735 Alanine aminotransferase 1 GPT 0.0046
3382 Glycolipid transfer protein GLTP 0.0046
6174 50S ribosomal protein L32 rpmF 0.0046
3014 Ribonuclease UK114 HRSP12 0.0046
3718 Hydrogen peroxide-inducible genes activator oxyR 0.0046
5428 Replication protein repA 0.0046
3617 Non-heme chloroperoxidase cpo 0.0046
5426 Non-heme chloroperoxidase cpo 0.0046
5427 Hydroxyquinol 1,2-dioxygenase chqB 0.0046
3018 HTH-type transcriptional regulator malT malT 0.0046
208 DNA-directed RNA polymerase beta' chain rpoC 0.0046
5774 DNA-directed RNA polymerase beta' chain rpoC 0.0046
6163 Copper-transporting ATPase 2 ATP7B 0.0045
6165 Copper-transporting ATPase 1 ATP7A 0.0045
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0045
1196 Complement decay-accelerating factor CD55 0.0045
474 Acetylcholinesterase ACHE 0.0045
6228 Nuclear receptor coactivator 1 NCOA1 0.0044
130 Prostacyclin synthase PTGIS 0.0044
1864 RET proto-oncogene RET 0.0044
2178 Metabotropic glutamate receptor 5 GRM5 0.0044
5645 DNA topoisomerase 4 subunit B parE 0.0044
6227 DNA topoisomerase 4 subunit B parE 0.0044
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0043
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0043
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0043
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0043
1483 Membrane copper amine oxidase AOC3 0.0043
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0043
6103 Arylamine N-acetyltransferase 1 NAT1 0.0042
3729 Citrate synthase gltA 0.0042
4575 Citrate synthase cit 0.0042
4580 Citrate synthase gltA 0.0042
2358 cAMP-specific 3',5'-cyclic phosphodiesterase 4D PDE4D 0.0042
6068 Guanylate cyclase soluble subunit alpha-2 GUCY1A2 0.0041
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.0041
3997 Cytochrome P450 24A1, mitochondrial CYP24A1 0.0041
6241 Nuclear receptor coactivator 2 NCOA2 0.0041
484 Tyrosine-protein kinase ABL2 ABL2 0.0041
1992 Vitamin D-binding protein GC 0.004
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.004
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.004
6508 Putative uncharacterized protein srtB 0.004
6543 Putative uncharacterized protein tcp14 0.004
6615 Putative uncharacterized protein MT0785 0.004
6623 Putative uncharacterized protein Not Available 0.004
6806 Putative uncharacterized protein AGR_C_2535 0.004
6813 Putative uncharacterized protein SAV4671 0.004
6815 Putative uncharacterized protein AFE_1514 0.004
6819 Putative uncharacterized protein RUMGNA_03254 0.004
6825 Putative uncharacterized protein CV_3270 0.004
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.004
4161 Furin FURIN 0.004
2314 Triosephosphate isomerase TPI 0.004
3417 Triosephosphate isomerase tpiA 0.004
3443 Triosephosphate isomerase tpiA 0.004
6346 Triosephosphate isomerase TPI1 0.004
2958 Probable tautomerase ydcE pptA 0.004
2573 Cocaine esterase cocE 0.004
7263 Cocaine esterase Not Available 0.004
2371 Pantothenate kinase coaA 0.0039
1541 Metalloproteinase mmp20 0.0039
3115 Ras-related protein Rab-9 RAB9A 0.0039
3603 Chlorocatechol 1,2-dioxygenase clcA 0.0039
1129 C-C chemokine receptor type 5 CCR5 0.0039
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0039
6067 Penicillin binding protein 2a mecA 0.0038
1275 Estrogen sulfotransferase SULT1E1 0.0038
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0038
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0038
85 Growth hormone receptor GHR 0.0038
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.0037
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.0037
6432 Transporter snf 0.0037
242 Asparagine synthetase [glutamine-hydrolyzing] ASNS 0.0037
444 Alcohol dehydrogenase 1B ADH1B 0.0037
4311 tRNA TRDMT1 0.0036
4325 tRNA trmD 0.0036
4328 tRNA trmD 0.0036
276 Sodium- and chloride-dependent GABA transporter 1 SLC6A1 0.0036
822 Aldose reductase AKR1B1 0.0036
291 Nitric-oxide synthase, endothelial NOS3 0.0036
4564 YvbK protein yvbK 0.0036
4567 Putative acyl-CoA thioester hydrolase HI0827 HI_0827 0.0036
4566 Acyl-CoA hydrolase BC_2038 0.0036
4572 Acyl-CoA hydrolase BH0798 0.0036
4576 Aac(6')-Ii protein aac(6')-Ii 0.0036
4577 4'-phosphopantetheinyl transferase sfp sfp 0.0036
2528 Fatty acid metabolism regulator protein fadR 0.0036
6740 Fatty acid metabolism regulator protein fadR 0.0036
4579 Serine acetyltransferase cysE 0.0036
6807 Serine acetyltransferase cysE 0.0036
819 Penicillin-binding protein 4 dacB 0.0036
3601 Dihydropteroate synthase 1 folP1 0.0036
3807 Dihydropteroate synthase 1 folP1 0.0036
3808 Dihydropteroate synthase 2 folP2 0.0036
2417 Chloramphenicol acetyltransferase cat 0.0036
3278 Chloramphenicol acetyltransferase cat 0.0036
2810 Dr hemagglutinin structural subunit draA 0.0035
185 Vasopressin V1a receptor AVPR1A 0.0035
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0035
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0035
939 50S ribosomal protein L3 rplC 0.0035
4024 Mitochondrial glutamate carrier 2 SLC25A18 0.0034
4025 Mitochondrial glutamate carrier 1 SLC25A22 0.0034
1912 Excitatory amino acid transporter 1 SLC1A3 0.0034
4019 Excitatory amino acid transporter 4 SLC1A6 0.0034
919 Glutamate receptor, ionotropic kainate 4 GRIK4 0.0034
4026 Aspartyl aminopeptidase DNPEP 0.0034
4022 Glutamate--ammonia ligase domain-containing protein 1 LGSN 0.0034
4021 Probable glutamyl-tRNA synthetase, mitochondrial EARS2 0.0034
4023 N-acetylglutamate synthase, mitochondrial NAGS 0.0034
4016 Excitatory amino acid transporter 5 SLC1A7 0.0034
4017 5-oxoprolinase OPLAH 0.0034
1047 Excitatory amino acid transporter 2 SLC1A2 0.0034
922 Glutamate receptor 4 GRIA4 0.0034
664 Glutamate decarboxylase 2 GAD2 0.0034
3890 Glutamate decarboxylase 2 GAD2 0.0034
924 Glutamate receptor, ionotropic kainate 3 GRIK3 0.0034
4020 Glutamyl aminopeptidase ENPEP 0.0034
4027 Glutamate receptor delta-1 subunit GRID1 0.0034
915 Delta 1-pyrroline-5-carboxylate synthetase ALDH18A1 0.0034
927 Metabotropic glutamate receptor 8 GRM8 0.0034
925 Metabotropic glutamate receptor 4 GRM4 0.0034
926 Metabotropic glutamate receptor 7 GRM7 0.0034
920 Glutamate receptor, ionotropic kainate 5 GRIK5 0.0034
4018 Glutamate receptor delta-2 subunit GRID2 0.0034
322 Vasopressin V2 receptor AVPR2 0.0034
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0034
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0033
518 Peroxidase/catalase T katG 0.0033
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0033
340 Apoptotic protease-activating factor 1 APAF1 0.0033
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.0033
5328 Prostaglandin F synthase Tb11.02.2310 0.0033
760 Fibroblast growth factor 1 FGF1 0.0032
65 Matrix metalloproteinase-9 Not Available 0.0032
6105 3-oxo-5-beta-steroid 4-dehydrogenase AKR1D1 0.0032
6677 Myelin P2 protein PMP2 0.0032
581 Cytochrome P450 2R1 CYP2R1 0.0032
1867 Major prion protein PRNP 0.0032
1759 85 kDa calcium-independent phospholipase A2 PLA2G6 0.0032
1770 Phospholipase C PLCL1 0.0032
2841 Phospholipase C plc 0.0032
3086 Plasmepsin-2 Not Available 0.0032
595 Fibrinogen alpha chain FGA 0.0032
140 30S ribosomal protein S9 rpsI 0.0031
6719 30S ribosomal protein S9 rpsI 0.0031
6725 30S ribosomal protein S9 rpsI 0.0031
319 Opioid receptor, sigma 1 OPRS1 0.0031
3489 Acetyl-coenzyme A synthetase acs 0.0031
2396 Formyl-coenzyme A transferase frc 0.0031
3457 Formyl-coenzyme A transferase frc 0.0031
4574 PROBABLE NAPHTHOATE SYNTHASE MENB menB 0.0031
3024 Crotonobetainyl-CoA:carnitine CoA-transferase caiB 0.0031
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0031
2409 Acetyl-CoA acetyltransferase, cytosolic ACAT2 0.0031
1063 Signal transducer and activator of transcription 5B STAT5B 0.0031
935 Proto-oncogene tyrosine-protein kinase Yes YES1 0.0031
4563 Acetyl transferase rimL 0.0031
4565 Aminoglycoside 6'-N-acetyltransferase aac(6')-Iy 0.0031
1227 Cytochrome b MT-CYB 0.0031
6386 Cytochrome b petB 0.0031
6937 Cytochrome b MT-CYB 0.0031
674 Dihydroorotate dehydrogenase homolog, mitochondrial PFF0160c 0.0031
3560 Gentamicin 3'-acetyltransferase aacC1 0.0031
3760 Penicillin-binding protein 5 precursor dacA 0.0031
625 Glutamate carboxypeptidase 2 FOLH1 0.0031
2578 Tubulin beta-3 chain TUBB3 0.003
2693 Heat-labile enterotoxin B chain eltB 0.003
4674 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase cumD 0.003
16 Adenosine A1 receptor ADORA1 0.003
3984 Probable glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial PET112L 0.003
3991 Glutamine-dependent NAD(+) synthetase NADSYN1 0.0029
5 Glutaminase liver isoform, mitochondrial GLS2 0.0029
917 Glutaminase kidney isoform, mitochondrial GLS 0.0029
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0029
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0029
636 Mitochondrial carnitine/acylcarnitine carrier protein SLC25A20 0.0029
109 Mitochondrial carnitine/acylcarnitine carrier protein CACL SLC25A29 0.0029
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.0029
5261 Phosphoribosylformylglycinamidine synthase purL 0.0029
668 Glutamate--cysteine ligase regulatory subunit GCLM 0.0029
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.0029
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.0029
6645 D-amino-acid oxidase DAO 0.0029
3813 Fibrinogen gamma chain FGG 0.0029
3812 Fibrinogen beta chain [Contains: Fibrinopeptide B] FGB 0.0029
3950 Cell division protein kinase 9 CDK9 0.0029
3968 Cell division protein kinase 8 CDK8 0.0029
1178 Adenosine A2a receptor ADORA2A 0.0029
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0029
4041 Microsomal glutathione S-transferase 2 MGST2 0.0029
646 Malate dehydrogenase, cytoplasmic MDH1 0.0029
4573 Histone acetyltransferase PCAF KAT2B 0.0029
2377 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Not Available 0.0029
2560 Galactoside O-acetyltransferase lacA 0.0029
3199 Phosphopantetheine adenylyltransferase coaD 0.0029
3543 Phosphopantetheine adenylyltransferase coaD 0.0029
3567 Phosphopantetheine adenylyltransferase coaD 0.0029
5289 Phosphopantetheine adenylyltransferase coaD 0.0029
663 Solute carrier family 12 member 4 SLC12A4 0.0029
53 Solute carrier family 12 member 5 SLC12A5 0.0029
5798 Mitogen-activated protein kinase 11 MAPK11 0.0028
665 Phosphoserine aminotransferase PSAT1 0.0028
4652 Phosphoserine aminotransferase serC 0.0028
801 Kynurenine/alpha-aminoadipate aminotransferase mitochondrial AADAT 0.0028
3895 Kynurenine--oxoglutarate transaminase 3 CCBL2 0.0028
420 Glutamate decarboxylase 1 GAD1 0.0028
3900 Glutamate decarboxylase 1 GAD1 0.0028
2248 Malate synthase G glcB 0.0028
3190 Malate synthase G glcB 0.0028
3697 Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase glmU 0.0028
3178 Formate acetyltransferase 1 pflB 0.0028
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.0028
666 NADP-dependent malic enzyme ME1 0.0028
233 Potassium channel subfamily K member 2 KCNK2 0.0028
215 Sodium channel protein type 11 subunit alpha SCN11A 0.0028
6207 30S ribosomal protein S14 rpsN 0.0028
6209 30S ribosomal protein S19 rpsS 0.0028
6712 30S ribosomal protein S19 rpsS 0.0028
6726 30S ribosomal protein S19 rpsS 0.0028
916 Metabotropic glutamate receptor 1 GRM1 0.0028
934 Proto-oncogene tyrosine-protein kinase Fyn FYN 0.0028
1278 Pro-epidermal growth factor EGF 0.0028
1200 AMBP protein AMBP 0.0028
3866 Serum amyloid A protein SAA1 0.0028
1932 Apolipoprotein E APOE 0.0028
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0027
1144 Hepatocyte growth factor receptor MET 0.0027
923 Glutamate receptor 3 GRIA3 0.0027
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0027
4173 Tyrosine-protein kinase JAK2 JAK2 0.0027
4404 FcbC1 protein fcbC 0.0027
1123 Eosinophil cationic protein RNASE3 0.0027
162 Retinoic acid receptor gamma-1 RARG 0.0027
11 NAD(P) transhydrogenase, mitochondrial NNT 0.0027
186 Glutamate--cysteine ligase catalytic subunit GCLC 0.0027
1671 Excitatory amino acid transporter 3 SLC1A1 0.0027
634 Squalene monooxygenase SQLE 0.0027
7196 Squalene monooxygenase ERG1 0.0027
889 3-oxoacyl-[acyl-carrier-protein] synthase 1 fabB 0.0027
6860 3-oxoacyl-[acyl-carrier-protein] synthase 1 kasA 0.0027
310 Solute carrier family 12 member 2 SLC12A2 0.0027
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0026
207 Glutathione synthetase GSS 0.0026
5269 Glutathione synthetase gshB 0.0026
174 Sigma 1-type opioid receptor SIGMAR1 0.0026
3877 Growth-inhibiting protein 18 GIG18 0.0026
2376 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase dapD 0.0026
210 Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase EPRS 0.0026
3913 Glutamic acid decarboxylase GAD65 0.0026
914 Formimidoyltransferase-cyclodeaminase FTCD 0.0026
426 Aspartate aminotransferase, mitochondrial GOT2 0.0026
412 Peroxisomal carnitine O-octanoyltransferase CROT 0.0026
5322 Oxidoreductase ydhF ydhF 0.0025
5333 Alcohol dehydrogenase, iron-containing TM_0920 0.0025
3772 3-oxoacyl-[acyl-carrier-protein] reductase fabG 0.0025
5342 NADH-dependent butanol dehydrogenase, putative TM_0820 0.0025
5326 Oxidoreductase, short chain dehydrogenase/reductase family TM_0441 0.0025
5157 Dehydrogenase/reductase SDR family member 11 DHRS11 0.0025
5346 Oxidoreductase, aldo/keto reductase family TM_1009 0.0025
5332 MtdA bifunctional protein mtdA 0.0025
3778 NAD(P) transhydrogenase subunit beta pntB 0.0025
3959 Cell division protein kinase 4 CDK4 0.0025
4403 Protein iolS iolS 0.0025
5343 NADP-dependent fatty aldehyde dehydrogenase aldH 0.0025
5330 General stress protein 69 yhdN 0.0025
4252 Penicillin-binding protein 5 dacA 0.0025
763 Tyrosine aminotransferase TAT 0.0025
5493 Tyrosine aminotransferase Not Available 0.0025
3482 Cell division protein kinase 7 CDK7 0.0025
2112 Toll-like receptor 9 TLR9 0.0025
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.0025
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.0025
586 Aspartate aminotransferase, cytoplasmic GOT1 0.0024
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0024
544 Potassium voltage-gated channel subfamily E member 1 KCNE1 0.0024
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0024
159 Penicillin-binding protein 2B penA 0.0024
6121 Penicillin-binding protein 2B penA 0.0024
6039 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A PDE11A 0.0024
615 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.0024
3138 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.0024
4568 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.0024
6370 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.0024
6231 Pepsin A PGA3 0.0024
5852 Type-2 angiotensin II receptor AGTR2 0.0024
251 Alcohol dehydrogenase 1A ADH1A 0.0024
4388 Aminoglycoside 2'-N-acetyltransferase aac 0.0024
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0024
795 Branched-chain-amino-acid aminotransferase, mitochondrial BCAT2 0.0024
3937 Fatty-acid amide hydrolase FAAH 0.0024
2596 Acetyl-CoA acetyltransferase phbA 0.0023
3955 Cell division protein kinase 6 CDK6 0.0023
332 Beta-lactamase blaZ 0.0023
2478 Beta-lactamase ampC 0.0023
2613 Beta-lactamase ampC 0.0023
2635 Beta-lactamase ampC 0.0023
2700 Beta-lactamase penP 0.0023
5445 Beta-lactamase blaB 0.0023
6019 Beta-lactamase SHV-7 0.0023
6701 Beta-lactamase cphA 0.0023
6100 BDNF/NT-3 growth factors receptor NTRK2 0.0023
4031 Glutathione S-transferase A1 GSTA1 0.0023
574 Branched-chain-amino-acid aminotransferase, cytosolic BCAT1 0.0023
654 Flavin reductase BLVRB 0.0023
569 Retinal dehydrogenase 2 ALDH1A2 0.0023
4034 Glutaredoxin-1 GLRX 0.0022
1928 Leukotriene C4 synthase LTC4S 0.0022
4043 Glutaredoxin-2, mitochondrial GLRX2 0.0022
910 Epididymal secretory glutathione peroxidase GPX5 0.0022
4036 Glutathione peroxidase 6 GPX6 0.0022
4037 Hypothetical protein GPX1 0.0022
4297 Hypothetical protein SP_1951 0.0022
4521 Hypothetical protein BC_2969 0.0022
4540 Hypothetical protein TM_1070 0.0022
4555 Hypothetical protein MT1739 0.0022
4569 Hypothetical protein mshD 0.0022
4578 Hypothetical protein PA3270 0.0022
4747 Hypothetical protein PA3967 0.0022
5177 Hypothetical protein TM_0096 0.0022
5194 Hypothetical protein PA1204 0.0022
5240 Hypothetical protein Rv2991 0.0022
5370 Hypothetical protein TM_1158 0.0022
5710 Hypothetical protein Tb927.5.1360 0.0022
4030 Thioredoxin domain-containing protein 12 TXNDC12 0.0022
4029 Microsomal glutathione S-transferase 3 MGST3 0.0022
911 Glutathione peroxidase 3 GPX3 0.0022
4039 CDNA FLJ23636 fis, clone CAS07176 GPX8 0.0022
903 Glutathione S-transferase A5 GSTA5 0.0022
4032 Microsomal glutathione S-transferase 1 MGST1 0.0022
4040 Glutathione peroxidase 7 GPX7 0.0022
907 Glutathione peroxidase 2 GPX2 0.0022
900 Glutathione S-transferase A4 GSTA4 0.0022
906 Glutathione peroxidase 1 GPX1 0.0022
4035 Glutathione S-transferase Mu 5 GSTM5 0.0022
4042 Glutathione transferase omega-2 GSTO2 0.0022
4033 S-formylglutathione hydrolase ESD 0.0022
4209 ATP-sensitive inward rectifier potassium channel 8 KCNJ8 0.0022
4038 Glutathione peroxidase 4 GPX4 0.0022
1975 Phospholipid hydroperoxide glutathione peroxidase, mitochondrial GPX4 0.0022
1056 Gamma-glutamyltranspeptidase 1 GGT1 0.0022
990 Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 0.0022
2375 ADP-L-glycero-D-manno-heptose-6-epimerase hldD 0.0022
5073 Ferredoxin--NADP reductase petH 0.0022
5076 Ferredoxin--NADP reductase fpr 0.0022
5119 Ferredoxin--NADP reductase petH 0.0022
5121 Ferredoxin--NADP reductase fpr 0.0022
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0022
6111 DNA polymerase epsilon subunit 4 POLE4 0.0022
2305 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 0.0022
3446 NADP-dependent alcohol dehydrogenase adh 0.0022
6112 DNA polymerase epsilon subunit 3 POLE3 0.0022
2286 Isocitrate dehydrogenase [NADP] icd 0.0022
2302 Isocitrate dehydrogenase [NADP] icd 0.0022
2771 Isocitrate dehydrogenase [NADP] icd 0.0022
4582 Putative pteridine reductase 2 ptr2 0.0022
6110 DNA polymerase epsilon subunit 2 POLE2 0.0022
6108 Ribonucleoside-diphosphate reductase subunit M2 B RRM2B 0.0022
6109 DNA polymerase epsilon catalytic subunit A POLE 0.0022
1714 Mitogen-activated protein kinase 3 MAPK3 0.0022
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.0022
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.0022
4628 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase gapN 0.0022
989 L-xylulose reductase DCXR 0.0022
2232 Interleukin-5 IL5 0.0022
164 Histamine H4 receptor HRH4 0.0021
298 Renin REN 0.0021
1593 Mucin-2 MUC2 0.0021
6506 Stathmin-4 STMN4 0.0021
707 72 kDa type IV collagenase MMP2 0.0021
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0021
2207 Rhodopsin RHO 0.0021
741 Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 0.0021
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0021
331 Retinol-binding protein I, cellular RBP1 0.0021
3090 Chitosanase csn 0.002
3319 Hydroxyacylglutathione hydrolase HAGH 0.002
4149 Nuclear factor NF-kappa-B p100 subunit NFKB2 0.002
1742 D-HSCDK2 CDK2deltaT 0.002
1771 Cell division control protein 2 homolog CDK1 0.002
3321 Cell division control protein 2 homolog CRK2 0.002
3611 Cytidine deaminase cdd 0.002
3707 Cytidine deaminase cdd 0.002
4211 Cytidine deaminase CDA 0.002
6297 Prostaglandin reductase 1 PTGR1 0.002
6862 Aldo-keto reductase family 1 member B10 AKR1B10 0.002
714 Glutathione reductase, mitochondrial GSR 0.002
897 Glutathione S-transferase kappa 1 GSTK1 0.002
898 Glutathione S-transferase A3 GSTA3 0.002
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.002
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.002
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.002
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.002
4531 Putative ketoacyl reductase actIII 0.002
3062 Aspartate-semialdehyde dehydrogenase asd 0.002
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.002
4218 Ribonucleoside-diphosphate reductase M2 subunit RRM2 0.002
1058 Cell division protein kinase 5 CDK5 0.002
4199 Sphingosine 1-phosphate receptor Edg-8 S1PR5 0.002
899 Glutathione S-transferase Mu 3 GSTM3 0.0019
905 Glutathione transferase omega-1 GSTO1 0.0019
1039 Histone deacetylase 9 HDAC9 0.0019
4103 Proteasome subunit beta type 2 PSMB2 0.0019
4102 Proteasome subunit beta type 5 PSMB5 0.0019
4101 Proteasome subunit beta type 1 PSMB1 0.0019
2499 Tubulin beta-2C chain TUBB2C 0.0019
2675 Pteridine reductase 1 PTR1 0.0019
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0019
2697 Uridine-cytidine kinase 2 UCK2 0.0019
1124 Sepiapterin reductase SPR 0.0019
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.0019
6048 Troponin C, skeletal muscle TNNC2 0.0018
1253 Interferon gamma IFNG 0.0018
2105 ATP-binding cassette sub-family G member 1 ABCG1 0.0018
745 Anti-Muellerian hormone type-2 receptor AMHR2 0.0018
825 Arsenical pump-driving ATPase ASNA1 0.0018
3435 Arsenical pump-driving ATPase arsA 0.0018
154 AFG3-like protein 2 AFG3L2 0.0018
486 Serine/threonine-protein kinase ALS2CR7 CDK15 0.0018
225 NEDD8-activating enzyme E1 regulatory subunit NAE1 0.0018
510 Serine/threonine-protein kinase receptor R3 ACVRL1 0.0018
733 Activin receptor type 1B ACVR1B 0.0018
483 A-Raf proto-oncogene serine/threonine-protein kinase ARAF 0.0018
21 Beta-adrenergic receptor kinase 2 ADRBK2 0.0018
377 Beta-adrenergic receptor kinase 1 ADRBK1 0.0018
395 ALK tyrosine kinase receptor Not Available 0.0018
476 RAC-alpha serine/threonine-protein kinase AKT1 0.0018
5998 Toll-like receptor 8 TLR8 0.0018
719 Retinoic acid receptor responder protein 1 RARRES1 0.0018
770 Retinoic acid-induced protein 3 GPRC5A 0.0018
712 Tubulin alpha chain TUB1 0.0018
1968 ATP-sensitive inward rectifier potassium channel 12 KCNJ12 0.0018
565 Extracellular calcium-sensing receptor CASR 0.0018
2165 Glutathione S-transferase Mu 2 GSTM2 0.0018
3312 Fatty acid-binding protein, brain FABP7 0.0018
857 Malate dehydrogenase, mitochondrial MDH2 0.0018
67 Prolyl 4-hydroxylase subunit alpha-1 P4HA1 0.0017
613 Atrial natriuretic peptide receptor A NPR1 0.0017
5432 Trafficking protein particle complex subunit 3 TRAPPC3 0.0017
5878 Alpha-7 nicotinic cholinergic receptor subunit CHRFAM7A 0.0017
229 Retinoic acid receptor beta RARB 0.0017
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0017
3830 Calreticulin CALR 0.0017
292 Activin receptor type-1 ACVR1 0.0017
901 Glutathione S-transferase Mu 4 GSTM4 0.0017
5288 Shikimate kinase aroK 0.0017
5287 Signaling protein Not Available 0.0017
5314 UPF0079 ATP-binding protein HI0065 HI_0065 0.0017
5293 Shikimate kinase 2 aroL 0.0017
5304 UPF0166 protein TM_0021 TM_0021 0.0017
4346 Polynucleotide kinase pseT 0.0017
5292 Putative partitioning protein TT_C1605 0.0017
5276 Chromosomal replication initiator protein dnaA dnaA 0.0017
5266 Activator of hgdC 0.0017
5259 Transcriptional regulator ntrC1 0.0017
6699 Transcriptional regulator Cgl2612 0.0017
2874 Nitrogenase iron protein 1 nifH1 0.0017
5283 D-alanine--D-alanine ligase B ddlB 0.0017
5281 Plasmid segregation protein parM parM 0.0017
3777 ATP-dependent Clp protease ATP-binding subunit clpA clpA 0.0017
5305 Phosphoribosylaminoimidazole carboxylase ATPase subunit purK 0.0017
5299 D-alanine--D-alanine ligase ddl 0.0017
6598 D-alanine--D-alanine ligase ddl 0.0017
5315 Chaperone protein htpG htpG 0.0017
5290 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0017
5638 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0017
5270 ATP-dependent Clp protease ATP-binding subunit clpX clpX 0.0017
5291 Glycogen synthase 1 glgA1 0.0017
5264 DNA replication protein REP 0.0017
5277 Preprotein translocase subunit secA secA 0.0017
4794 Phosphoenolpyruvate carboxykinase [ATP] pckA 0.0017
5275 Multidrug resistance ABC transporter ATP-binding and permease protein lmrA 0.0017
1549 Heat shock 70 kDa protein 1 HSPA1A 0.0017
5284 Large T antigen Not Available 0.0017
4992 Cytochrome c peroxidase Not Available 0.0017
5308 Preprotein translocase secA 1 subunit secA1 0.0017
5285 Kinesin heavy chain KIF5B 0.0017
2091 Endoplasmin HSP90B1 0.0017
849 Activated CDC42 kinase 1 TNK2 0.0017
730 Retinoic acid receptor alpha RARA 0.0017
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.0016
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0016
820 Glycine receptor subunit alpha-2 GLRA2 0.0016
1768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit GNG2 0.0016
1268 Neuropeptide S receptor NPSR1 0.0016
1571 G protein-activated inward rectifier potassium channel 1 KCNJ3 0.0016
1581 G protein-activated inward rectifier potassium channel 2 KCNJ6 0.0016
3616 Fatty acid-binding protein, epidermal FABP5 0.0016
5431 Lipid binding protein Not Available 0.0016
5433 UPF0230 protein TM_1468 TM_1468 0.0016
5430 Hepatocyte nuclear factor 4-gamma HNF4G 0.0016
821 Acetyl-coenzyme A synthetase 2-like, mitochondrial ACSS1 0.0016
704 Long-chain-fatty-acid--CoA ligase 1 ACSL1 0.0016
386 Acetyl-coenzyme A synthetase, cytoplasmic ACSS2 0.0016
297 Adenylate cyclase type 1 ADCY1 0.0016
289 Cytosolic purine 5'-nucleotidase NT5C2 0.0016
173 Toll-like receptor 7 TLR7 0.0016
6034 Hydroxyindole O-methyltransferase ASMT 0.0016
6035 Nuclear receptor ROR-beta RORB 0.0016
6036 Eosinophil peroxidase EPX 0.0016
3233 Bile acid receptor NR1H4 0.0015
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0015
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0015
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0015
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0015
748 5'-AMP-activated protein kinase catalytic subunit alpha-1 PRKAA1 0.0015
473 L-lactate dehydrogenase A chain LDHA 0.0015
6073 Potassium channel subfamily K member 9 KCNK9 0.0015
6072 Potassium channel subfamily K member 3 KCNK3 0.0015
1341 Histamine H3 receptor HRH3 0.0014
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0014
2240 Cell division protein kinase 2 CDK2 0.0014
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0014
6032 PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) fas 0.0014
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0014
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.0014
2300 Lysozyme E 0.0014
3633 Lysozyme R 0.0014
5597 Lysozyme 17 0.0014
765 Indoleamine 2,3-dioxygenase IDO1 0.0014
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0014
277 Purine nucleoside phosphorylase PNP 0.0014
2870 Purine nucleoside phosphorylase punA 0.0014
2945 Purine nucleoside phosphorylase punA 0.0014
4659 Purine nucleoside phosphorylase TM_1596 0.0014
4825 Purine nucleoside phosphorylase TTHA1435 0.0014
740 Argininosuccinate synthase ASS1 0.0013
865 Argininosuccinate synthase ASS1 0.0013
2680 Argininosuccinate synthase argG 0.0013
3194 Argininosuccinate synthase argG 0.0013
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.0013
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0013
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0013
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0013
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0013
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0013
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0013
4106 Guanylate kinase GUK1 0.0013
4516 Guanylate kinase gmk 0.0013
4837 Cag-alfa cag-alfa 0.0013
5682 Ribonuclease pancreatic RNASE1 0.0013
3390 Aminoglycoside 3'-phosphotransferase aphA 0.0013
6029 Aminoglycoside 3'-phosphotransferase aphA1 0.0013
5646 Galactokinase GALK1 0.0013
4838 PMS1 protein homolog 2 PMS2 0.0013
4839 DNA polymerase III subunit tau dnaX 0.0013
5302 TrwB trwB 0.0013
5265 FtsH ftsH 0.0013
5189 Trimethylamine dehydrogenase tmd 0.0013
4774 NTPase P4 Not Available 0.0013
6277 Heat shock cognate 71 kDa protein HSPA8 0.0013
661 ADP/ATP translocase 1 SLC25A4 0.0013
2270 Dephospho-CoA kinase coaE 0.0013
2284 Adenylate kinase adk 0.0013
2296 Adenylate kinase adk 0.0013
2311 Adenylate kinase adk 0.0013
2312 Adenylate kinase Not Available 0.0013
3470 Hypothetical protein MG245 homolog MPN_348 0.0013
283 SEC14-like protein 2 SEC14L2 0.0013
3175 Glutamate--cysteine ligase gshA 0.0013
3426 Glutamine synthetase glnA 0.0013
3987 Glutamine synthetase GLUL 0.0013
2751 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0013
4755 Holliday junction ATP-dependent DNA helicase ruvB ruvB 0.0013
5295 2-keto-3-deoxy-gluconate kinase TT_P0036 0.0013
6021 Adenosine kinase ADK 0.0013
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0013
1152 Glycogen phosphorylase, muscle form PYGM 0.0013
6131 Carbonic anhydrase 14 CA14 0.0013
6459 Glycodelin PAEP 0.0013
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0013
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0013
2683 Mono-ADP-ribosyltransferase C3 C3 0.0013
6116 Gastric triacylglycerol lipase LIPF 0.0012
3806 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A 0.0012
5590 N utilization substance protein B homolog nusB 0.0012
5598 Glycerol uptake operon antiterminator-related protein TM_1436 0.0012
5586 Pleckstrin homology domain-containing family A member 1 PLEKHA1 0.0012
5577 N5-carboxyaminoimidazole ribonucleotide mutase purE 0.0012
3792 KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase eda 0.0012
2838 Ribose-5-phosphate isomerase A rpiA 0.0012
2952 Ribose-5-phosphate isomerase A rpiA 0.0012
5595 Ribose-5-phosphate isomerase A rpiA 0.0012
4695 UPF0124 protein yfiH yfiH 0.0012
5060 Intron-associated endonuclease 1 ITEVIR 0.0012
5593 Transferase Not Available 0.0012
5588 Cell division protein FtsY TM_0570 0.0012
5591 Complement component C8 gamma chain C8G 0.0012
5587 Iron(III)-binding periplasmic protein fbpA 0.0012
5583 RNA 3'-terminal phosphate cyclase rtcA 0.0012
5582 Regulator of transcription; stringent starvation protein A sspA 0.0012
5592 Ribonucleoside-diphosphate reductase subunit beta nrdF 0.0012
5581 Beta-fructosidase bfrA 0.0012
5600 Pyruvate decarboxylase pdc 0.0012
4375 Glutamine synthetase 1 glnA1 0.0012
5575 Short tail fiber protein 12 0.0012
5580 Hexon protein PII 0.0012
5574 Invasin YPTB1668 0.0012
605 Fumarate reductase flavoprotein subunit frdA 0.0012
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0012
3673 Fumarate reductase flavoprotein subunit fccA 0.0012
4912 Fumarate reductase flavoprotein subunit ifcA 0.0012
6549 Fumarate reductase flavoprotein subunit frdA 0.0012
3823 Cytokine receptor common gamma chain IL2RG 0.0012
2107 Microtubule-associated protein 1A MAP1A 0.0012
338 DNA polymerase UL30 0.0012
379 DNA polymerase UL54 0.0012
697 DNA polymerase ORF28 0.0012
2482 DNA polymerase 43 0.0012
4104 DNA polymerase BALF5 0.0012
6122 Carbonic anhydrase 3 CA3 0.0012
1295 Fatty acid synthase FASN 0.0012
2390 Nonsecretory ribonuclease RNASE2 0.0012
5312 Kinesin-like protein KIF1A KIF1A 0.0012
2922 Glycerol kinase glpK 0.0012
5271 Focal adhesion kinase 1 PTK2 0.0012
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.0012
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0012
2282 Protein recA recA 0.0011
2315 Protein recA recA 0.0011
2332 Protein recA recA 0.0011
5263 Protein recA recA 0.0011
408 Riboflavin kinase RFK 0.0011
754 Pancreatic triacylglycerol lipase PNLIP 0.0011
2615 Chemotaxis protein cheA cheA 0.0011
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0011
1881 Hexokinase-1 HK1 0.0011
2950 Inositol-trisphosphate 3-kinase A ITPKA 0.0011
1467 Tumor necrosis factor ligand superfamily member 13B TNFSF13B 0.0011
2892 Acetylglutamate kinase argB 0.0011
3550 Acetylglutamate kinase argB 0.0011
3669 Ribokinase rbsK 0.0011
6857 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial PDK2 0.0011
3132 Tryptophan synthase alpha chain trpA 0.0011
6568 Tryptophan synthase alpha chain trpA 0.0011
1374 Natriuretic peptides B NPPB 0.0011
1827 Gap junction alpha-1 protein GJA1 0.0011
1908 Vascular cell adhesion protein 1 VCAM1 0.0011
5006 RNASE4 protein RNASE4 0.0011
2555 Pol polyprotein pol 0.0011
3242 Pol polyprotein gag-pol 0.0011
3471 Pol polyprotein gag-pro-pol 0.0011
5256 Pol polyprotein pol 0.0011
6469 Pol polyprotein gag-pol 0.0011
6565 Pol polyprotein Not Available 0.0011
3085 Molybdopterin-guanine dinucleotide biosynthesis protein A mobA 0.0011
4533 Glyoxalase family protein BC_1747 0.0011
724 Interleukin-2 receptor alpha chain IL2RA 0.0011
717 Interleukin-2 receptor subunit beta IL2RB 0.0011
6832 Serine/threonine-protein kinase SRPK2 SRPK2 0.001
788 Creatine kinase M-type CKM 0.001
1810 Protein S100-A1 S100A1 0.001
6097 Protein S100-A2 S100A2 0.001
2727 S-adenosylmethionine synthetase metK 0.001
6390 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 ATP2A1 0.001
4228 Keratin, type II cytoskeletal 7 KRT7 0.001
2461 D-alanyl-D-alanine carboxypeptidase Not Available 0.001
5756 D-alanyl-D-alanine carboxypeptidase dac 0.001
4948 Cytochrome c-553 Not Available 0.001
493 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 0.001
4923 Cytochrome c3 DvMF_2499 0.001
4945 Cytochrome c3 Not Available 0.001
4949 Cytochrome c3 DVU_3171 0.001
4968 Cytochrome c3 cytc3 0.001
4997 Cytochrome c3 SO_2727 0.001
5219 Cytochrome c3 cyd 0.001
4902 Nine-heme cytochrome c Ddes_2038 0.001
3189 High-molecular-weight cytochrome c hmcA 0.001
2334 Dethiobiotin synthetase bioD 0.001
6555 Dethiobiotin synthetase bioD 0.001
2817 Phosphoribosylglycinamide formyltransferase 2 purT 0.001
512 DNA-directed RNA polymerase alpha chain rpoA 0.001
5772 DNA-directed RNA polymerase alpha chain rpoA 0.001
2603 Beta-lactamase II blm 0.001
2521 Cell division protein ftsZ ftsZ 0.001
3301 Cell division protein ftsZ ftsZ 0.001
2149 Angiogenin ANG 0.001
3583 6-phosphogluconolactonase pgl 0.001
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.001
61 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.001
2644 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.001
2710 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.001
2268 Cholesterol oxidase choB 0.0009
2822 Cholesterol oxidase choA 0.0009
941 Betaine--homocysteine S-methyltransferase 1 BHMT 0.0009
2942 Sialidase nanH 0.0009
3546 Sialidase nedA 0.0009
3486 Fumarate hydratase class II fumC 0.0009
48 Pyridoxal kinase PDXK 0.0009
2511 MAP kinase-activated protein kinase 2 MAPKAPK2 0.0009
2869 1-deoxy-D-xylulose 5-phosphate reductoisomerase dxr 0.0009
268 Adenosine A2b receptor ADORA2B 0.0009
2452 Tryptophanyl-tRNA synthetase trpS 0.0009
828 Phenylalanine-4-hydroxylase PAH 0.0009
3109 Phenylalanine-4-hydroxylase phhA 0.0009
2317 UDP-N-acetylmuramoylalanine--D-glutamate ligase murD 0.0009
1048 Protein S100-A13 S100A13 0.0009
2226 Protein S100-A12 S100A12 0.0009
6395 Myosin-14 MYH14 0.0009
2251 Thymidylate kinase tmk 0.0009
2254 Thymidylate kinase DTYMK 0.0009
3522 Thymidylate kinase tmk 0.0009
2805 Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 HS3ST3A1 0.0009
816 Biliverdin reductase A BLVRA 0.0009
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0009
2283 Steroid Delta-isomerase ksi 0.0009
2920 Steroid Delta-isomerase ksi 0.0009
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0009
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0009
2298 Cytochrome P450-cam camC 0.0009
4386 Hemoglobin-like protein HbN glbN 0.0009
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0009
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0009
390 Adenosine A3 receptor ADORA3 0.0009
1422 Serine/threonine-protein kinase 6 AURKA 0.0009
810 Heme oxygenase 1 HMOX1 0.0009
3391 Heme oxygenase 1 pbsA1 0.0009
411 Glycine N-methyltransferase GNMT 0.0009
2132 Protein S100-B S100B 0.0009
3404 Exotoxin A eta 0.0008
3379 Kinesin-like protein KIF11 KIF11 0.0008
219 NADH-ubiquinone oxidoreductase chain 3 MT-ND3 0.0008
343 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NDUFC1 0.0008
236 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NDUFA6 0.0008
755 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NDUFA3 0.0008
353 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 NDUFA4L2 0.0008
300 NADH-ubiquinone oxidoreductase chain 4L MT-ND4L 0.0008
374 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NDUFB1 0.0008
475 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NDUFB2 0.0008
99 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NDUFS5 0.0008
30 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NDUFV3 0.0008
446 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NDUFA7 0.0008
525 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NDUFA5 0.0008
270 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NDUFB5 0.0008
104 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NDUFS6 0.0008
247 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUFA1 0.0008
417 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NDUFB6 0.0008
324 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NDUFB4 0.0008
598 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NDUFA11 0.0008
582 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NDUFA13 0.0008
190 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 NDUFA4 0.0008
602 Acyl carrier protein, mitochondrial NDUFAB1 0.0008
609 15-hydroxyprostaglandin dehydrogenase [NAD+] HPGD 0.0008
405 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NDUFA8 0.0008
313 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NDUFB3 0.0008
384 NADH-ubiquinone oxidoreductase chain 6 MT-ND6 0.0008
607 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NDUFA2 0.0008
555 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 0.0008
656 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 0.0008
746 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NDUFB8 0.0008
644 Heme oxygenase 2 HMOX2 0.0008
4982 Heme oxygenase 2 pbsA2 0.0008
41 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NDUFS8 0.0008
50 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating NSDHL 0.0008
335 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NDUFA9 0.0008
568 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NDUFB7 0.0008
216 Aldehyde dehydrogenase 3B2 ALDH3B2 0.0008
9 Estradiol 17-beta-dehydrogenase 2 HSD17B2 0.0008
152 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NDUFV2 0.0008
829 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NDUFA12 0.0008
145 Corticosteroid 11-beta-dehydrogenase isozyme 2 HSD11B2 0.0008
721 NADH-ubiquinone oxidoreductase chain 2 MT-ND2 0.0008
91 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NDUFA10 0.0008
107 C-4 methylsterol oxidase SC4MOL 0.0008
608 NADH-ubiquinone oxidoreductase chain 4 MT-ND4 0.0008
539 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NDUFV1 0.0008
496 Aldehyde dehydrogenase 3B1 ALDH3B1 0.0008
272 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NDUFB10 0.0008
372 Estradiol 17-beta-dehydrogenase 3 HSD17B3 0.0008
729 GDP-L-fucose synthetase TSTA3 0.0008
3463 GDP-L-fucose synthetase fcl 0.0008
487 Aldo-keto reductase family 1 member C4 AKR1C4 0.0008
167 L-lactate dehydrogenase C chain LDHC 0.0008
326 L-lactate dehydrogenase A-like 6A LDHAL6A 0.0008
141 3-hydroxyisobutyrate dehydrogenase, mitochondrial HIBADH 0.0008
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.0008
3726 D-3-phosphoglycerate dehydrogenase serA 0.0008
4291 D-3-phosphoglycerate dehydrogenase serA 0.0008
206 3-keto-steroid reductase HSD17B7 0.0008
258 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial ALDH6A1 0.0008
196 D-beta-hydroxybutyrate dehydrogenase, mitochondrial BDH1 0.0008
231 Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic GPD1 0.0008
271 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial ALDH4A1 0.0008
14 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial IDH3A 0.0008
112 L-lactate dehydrogenase A-like 6B LDHAL6B 0.0008
616 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial IDH3B 0.0008
671 Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial PDHA2 0.0008
628 Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial PDHA1 0.0008
848 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial IDH3G 0.0008
34 7-dehydrocholesterol reductase DHCR7 0.0008
662 Fatty aldehyde dehydrogenase ALDH3A2 0.0008
288 Trifunctional enzyme subunit alpha, mitochondrial HADHA 0.0008
711 UDP-glucose 6-dehydrogenase UGDH 0.0008
3672 UDP-glucose 6-dehydrogenase hasB 0.0008
531 Aldehyde dehydrogenase X, mitochondrial ALDH1B1 0.0008
637 NADH-ubiquinone oxidoreductase chain 5 MT-ND5 0.0008
149 Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 0.0008
643 Peroxisomal bifunctional enzyme EHHADH 0.0008
548 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NDUFS1 0.0008
393 GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase H6PD 0.0008
22 30S ribosomal protein S4 rpsD 0.0008
6714 30S ribosomal protein S4 rpsD 0.0008
3456 Heat shock protein HSP 90-beta HSP90AB1 0.0008
2325 Sulfotransferase family cytosolic 2B member 1 SULT2B1 0.0008
5579 Carboxypeptidase B CPB1 0.0008
3822 Actin, alpha skeletal muscle ACTA1 0.0008
3478 Glucose-1-phosphate thymidylyltransferase rmlA 0.0008
4277 Glucose-1-phosphate thymidylyltransferase rmlA 0.0008
3384 Macrophage migration inhibitory factor MIF 0.0008
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0008
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0008
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.0008
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.0008
396 Alcohol dehydrogenase 4 ADH4 0.0008
363 NADP-dependent malic enzyme, mitochondrial ME3 0.0008
328 Sorbitol dehydrogenase SORD 0.0008
597 Dihydropteridine reductase QDPR 0.0008
128 Adenine phosphoribosyltransferase APRT 0.0008
1360 Sphingomyelin phosphodiesterase SMPD1 0.0008
3221 Cytochrome c4 cc4 0.0008
509 Thymidine kinase TK 0.0008
570 Thymidine kinase TK 0.0008
2559 Thymidine kinase TK 0.0008
3430 Thymidine kinase tdk 0.0008
3518 Thymidine kinase TK 0.0008
5301 Thymidine kinase tdk 0.0008
5771 Thymidine kinase ORF36 0.0008
7009 Thymidine kinase ORF36 0.0008
1649 Small inducible cytokine A2 CCL2 0.0008
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.0008
1025 Aquaporin-1 AQP1 0.0008
12 Alcohol dehydrogenase class 3 ADH5 0.0008
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0008
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0008
77 L-lactate dehydrogenase B chain LDHB 0.0008
1721 Glycogen synthase kinase-3 beta GSK3B 0.0008
6893 Calcium/calmodulin-dependent protein kinase type II gamma chain CAMK2G 0.0007
74 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial DLAT 0.0007
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0007
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0007
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0007
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0007
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0007
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0007
6026 Alcohol dehydrogenase 6 ADH6 0.0007
248 Pyrroline-5-carboxylate reductase 1 PYCR1 0.0007
802 Pyrroline-5-carboxylate reductase 2 PYCR2 0.0007
626 Cysteine dioxygenase type 1 CDO1 0.0007
296 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial MTHFD2 0.0007
110 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.0007
13 Aminomethyltransferase, mitochondrial AMT 0.0007
627 11-cis retinol dehydrogenase RDH5 0.0007
640 Aldehyde dehydrogenase 1A3 ALDH1A3 0.0007
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0007
6134 Sodium channel subunit beta-3 SCN3B 0.0007
6133 Sodium channel subunit beta-2 SCN2B 0.0007
6135 Sodium channel subunit beta-4 SCN4B 0.0007
6132 Sodium channel subunit beta-1 SCN1B 0.0007
6129 Carbonic anhydrase-related protein 11 CA11 0.0007
6127 Carbonic anhydrase-related protein CA8 0.0007
6128 Carbonic anhydrase-related protein 10 CA10 0.0007
2290 ADP-ribosyl cyclase 2 BST1 0.0007
226 Gonadotropin-releasing hormone receptor GNRHR 0.0007
1830 5'-nucleotidase NT5E 0.0007
1507 Cytochrome c CYCS 0.0007
125 DNA polymerase beta POLB 0.0007
57 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I HSD3B1 0.0006
144 Hemoglobin subunit alpha HBA1 0.0006
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.0006
279 Tyrosinase TYR 0.0006
6130 Carbonic anhydrase 13 CA13 0.0006
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0006
3126 Poly [ADP-ribose] polymerase 1 PARP1 0.0006
4954 Soluble cytochrome b558 Not Available 0.0006
4943 Cytochrome c6 petJ 0.0006
4916 Cyanoglobin glbN 0.0006
5000 HemO hemO 0.0006
4934 Cytochrome c-551 nirM 0.0006
5218 Cytochrome c-551 nirM 0.0006
4947 Bacterial hemoglobin vhb 0.0006
4942 Diheme cytochrome c napB napB 0.0006
4994 Hemoglobin-like protein HbO glbO 0.0006
4981 Iron-starvation protein PigA pigA 0.0006
4984 Neuroglobin NGB 0.0006
4975 Cytochrome c-556 RPA3973 0.0006
4905 Cytochrome c2 Not Available 0.0006
4939 Cytochrome c2 cycA 0.0006
4964 Cytochrome c2 cycA 0.0006
4979 Cytochrome c2 cycA 0.0006
6673 Cytochrome c2 cycA 0.0006
4915 Cytochrome c-550 psbV 0.0006
4959 Cytochrome c-550 psbV 0.0006
5216 Cytochrome c-550 psbV 0.0006
4925 Cytochrome c-type protein SHP shp 0.0006
4935 Cytochrome c-554 cycA1 0.0006
4910 Cytoglobin CYGB 0.0006
4936 Cytochrome c2 iso-2 Not Available 0.0006
4998 Hemoglobin-like protein yjbI yjbI 0.0006
3116 Bacterioferritin bfr 0.0006
4906 Bacterioferritin bfr 0.0006
4965 Bacterioferritin bfr 0.0006
4909 CooA protein cooA 0.0006
4961 Hemophore HasA hasA 0.0006
4971 Nonaheme cytochrome c hmcA 0.0006
4907 Cytochrome c-L moxG 0.0006
6865 Cytochrome c-L moxG 0.0006
4904 Cytochrome c family protein GSU1996 0.0006
4937 Cytochrome oxidase subunit II rcoxA 0.0006
4931 Cytochrome P450 167A1 CYP167A1 0.0006
4989 Cytochrome c551 peroxidase ccp 0.0006
5222 Cytochrome c551 peroxidase ccpA 0.0006
4976 Apocytochrome f petA 0.0006
6407 Apocytochrome f petA 0.0006
4903 Methyl-accepting chemotaxis protein Tar4 0.0006
4764 Cytochrome P450 165C4 CYP165C4 0.0006
4960 Putative cytochrome P450-family protein SCO7417 0.0006
4922 Cytochrome c, putative SO_4144 0.0006
4926 Heme-based aerotactic transducer hemAT hemAT 0.0006
4999 Cytochrome P450 165B3 CYP165B3 0.0006
4972 P450cin cinA 0.0006
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0006
4993 Hydroxylamine oxidoreductase hao1 0.0006
4952 Catalase/peroxidase katA 0.0006
3093 Catalase HPII katE 0.0006
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0006
1569 G1/S-specific cyclin-D1 CCND1 0.0006
5221 Cytochrome c3, 13 kDa Not Available 0.0006
3152 Cytochrome c'' cycA 0.0006
5220 Split-Soret cytochrome c Ddes_2150 0.0006
3700 Cytochrome c-552 precursor nrfA 0.0006
1262 Corticotropin-lipotropin POMC 0.0005
6743 Non-fluorescent flavoprotein luxF 0.0005
6753 Apolipoprotein M APOM 0.0005
6752 Guanylyl cyclase-activating protein 1 GUCA1A 0.0005
394 Calcineurin subunit B isoform 1 PPP3R1 0.0005
6742 Recoverin RCVRN 0.0005
6747 Chalcone/stilbene synthase family protein MT1417 0.0005
6741 Peroxisomal 3,2-trans-enoyl-CoA isomerase PECI 0.0005
6522 Hepatocyte nuclear factor 4-alpha HNF4A 0.0005
6751 Gag polyprotein gag 0.0005
6746 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform PPP3CA 0.0005
6749 Polyprotein Not Available 0.0005
3007 Carbonic anhydrase 12 CA12 0.0005
4205 Carbonic anhydrase 9 CA9 0.0005
3127 Nitrite reductase nirS 0.0005
3284 Nitrite reductase nirS 0.0005
5961 Insulin INS 0.0005
2236 Casein kinase II subunit alpha CSNK2A1 0.0005
6527 Lymphocyte antigen 96 LY96 0.0005
6755 Poliovirus receptor PVR 0.0005
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0004
3405 Quinohaemoprotein ethanol dehydrogenase type-1 qheDH 0.0004
6750 ADP-ribosylation factor 6 ARF6 0.0004
4920 Peroxidase/catalase katG 0.0004
6524 Protein tonB tonB 0.0004
2119 Cytochrome b5 CYB5A 0.0004
4990 PpcA ppcA 0.0004
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0004
4988 Sulfite oxidase, mitochondrial SUOX 0.0004
3375 Acidic cytochrome c3 Not Available 0.0004
3570 Cytochrome P450 152A1 cypC 0.0004
2915 Sensor protein fixL fixL 0.0004
4944 Sensor protein fixL fixL 0.0004
4813 Heme oxygenase hmuO 0.0004
5769 Heme oxygenase Not Available 0.0004
4289 Cytochrome P450 TT_P0059 0.0004
6262 Cytochrome P450 staP 0.0004
4385 Cytochrome c' Not Available 0.0004
4967 Cytochrome c' cycA 0.0004
5038 Cytochrome c' Not Available 0.0004
5223 Cytochrome c' cycP 0.0004
2230 Catalase CAT 0.0004
3249 Catalase katA 0.0004
3625 Catalase katA 0.0004
4539 Catalase katA 0.0004
4941 Catalase katB 0.0004
2616 Ganglioside GM2 activator GM2A 0.0004
2435 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0004
6613 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0004
1176 Mitogen-activated protein kinase 1 MAPK1 0.0004
3670 Soluble cytochrome b562 precursor cybC 0.0004
3411 Cytochrome P450 121 cyp121 0.0004
3291 Cytochrome c-552 cycA 0.0004
4927 Cytochrome c-552 nrfA 0.0004
4938 Cytochrome c-552 cycA 0.0004
4953 Cytochrome c-552 nrfA 0.0004
5217 Cytochrome c-552 cycM 0.0004
2617 Nitric oxide synthase oxygenase nos 0.0004
2701 Nitric oxide synthase oxygenase nos 0.0004
2297 Genome polyprotein Not Available 0.0004
2322 Genome polyprotein Not Available 0.0004
2694 Genome polyprotein Not Available 0.0004
2719 Genome polyprotein Not Available 0.0004
2860 Genome polyprotein Not Available 0.0004
2928 Genome polyprotein Not Available 0.0004
3160 Genome polyprotein Not Available 0.0004
3260 Genome polyprotein Not Available 0.0004
4783 Genome polyprotein Not Available 0.0004
5726 Genome polyprotein Not Available 0.0004
5779 Genome polyprotein Not Available 0.0004
5867 Genome polyprotein Not Available 0.0004
6253 Genome polyprotein Not Available 0.0004
6301 Genome polyprotein Not Available 0.0004
6380 Genome polyprotein Not Available 0.0004
6381 Genome polyprotein Not Available 0.0004
6437 Genome polyprotein Not Available 0.0004
6520 Genome polyprotein Not Available 0.0004
6521 Genome polyprotein Not Available 0.0004
6652 Genome polyprotein Not Available 0.0004
6734 Genome polyprotein Not Available 0.0004
6735 Genome polyprotein Not Available 0.0004
6736 Genome polyprotein Not Available 0.0004
6737 Genome polyprotein Not Available 0.0004
6738 Genome polyprotein Not Available 0.0004
6739 Genome polyprotein Not Available 0.0004
6744 Genome polyprotein Not Available 0.0004
6748 Genome polyprotein Not Available 0.0004
6894 Genome polyprotein Not Available 0.0004
6898 Genome polyprotein Not Available 0.0004
3102 Flavohemoprotein hmp 0.0004
4969 Flavohemoprotein hmp 0.0004
6316 ADP-ribosylation factor 1 ARF1 0.0004
864 Gag-Pol polyprotein gag-pol 0.0003
2237 Gag-Pol polyprotein gag-pol 0.0003
2326 Gag-Pol polyprotein gag-pol 0.0003
2451 Gag-Pol polyprotein gag-pol 0.0003
2901 Gag-Pol polyprotein gag-pol 0.0003
3165 Gag-Pol polyprotein gag-pol 0.0003
3722 Gag-Pol polyprotein gag-pol 0.0003
6306 Gag-Pol polyprotein gag-pol 0.0003
6624 Gag-Pol polyprotein gag-pol 0.0003
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0003
2972 6-deoxyerythronolide B hydroxylase eryF 0.0003
4608 Putative cytochrome P450 SCO1207 0.0003
4963 Putative cytochrome P450 SCO2884 0.0003
6254 Putative cytochrome P450 SCO6998 0.0003
2427 Ferrichrome-iron receptor fhuA 0.0003
358 Cystathionine beta-synthase CBS 0.0003
6264 cAMP-dependent protein kinase inhibitor alpha PKIA 0.0003
693 Hemoglobin subunit beta HBB 0.0003
6268 Hydroxyacid oxidase 1 HAO1 0.0003
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0003
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