DT-Web

DB00693 - Fluorescein


Identification
Name Fluorescein
Accession Number DB00693 (APRD00979, DB07777, EXPT01447)
Type small molecule
Description A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma. It has been approved by FDA for use in externally applied drugs and cosmetics. (From Merck Index, 12th ed; American Medical Association Drug Evaluations; 1995, p2275)
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 332.3063
Groups approved
Monoisotopic Weight 332.068473494
Pharmacology
Indication For diagnostic imaging. Primarily indicated in diagnostic fluorescein angiography or angioscopy of the fundus and of the iris vasculature.
Mechanism of action Fluorescein sodium is used extensively as a diagnostic tool in the field of ophthalmology. Fluorescein is a fluorescent compound or fluorophore having a maximum absorbance of 494 m and an emission maximum of 521 nm. The yellowish-green fluorescence of the compound can be used to demarcate the vascular area under observation, distinguishing it from adjacent areas. It is applied topically in the form of a drop or it can be injected intravenously to produce a fluorescein angiogram. Topical fluorescein is a useful tool in the diagnosis of corneal abrasions, corneal ulcers, herpetic corneal infections, and dry eye. Fluorescein angiography is used to diagnose and categorize macular degeneration, diabetic retinopathy, inflammatory intraocular conditions, and intraocular tumors.
Absorption Rapidly distributed
Protein binding 85%
Biotransformation Not Available
Route of elimination Fluorescein and its metabolites are mainly eliminated via renal excretion.
Toxicity Not Available
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Ig kappa chain V-II region RPMI 6410
Name Ig kappa chain V-II region RPMI 6410
Gene Name Not Available
Pharmacological action no
Actions other
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.4005
DNA
Name DNA
Gene Name Not Available
Pharmacological action no
Actions other
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Estevez-Torres A, Gosse C, Saux TL, Allemand JF, Croquette V, Berthoumieux H, Lemarchand A, Jullien L: Fourier Analysis To Measure Diffusion Coefficients and Resolve Mixtures on a Continuous Electrophoresis Chip. Anal Chem. 2007 Sep 25;. - Pubmed
  • Huang YM, Qi YJ, Zhu YL, Tong DY, Wu XY: [Polymorphism of 7 Y-STR loci in Chinese populations by multiplex PCR genotyping using fluorescein-labeled primers.] Yi Chuan. 2007 Oct;29(10):1214-22. - Pubmed
  • Pennathur S, Baldessari F, Santiago JG, Kattah MG, Steinman JB, Utz PJ: Free-Solution Oligonucleotide Separation in Nanoscale Channels. Anal Chem. 2007 Sep 21;. - Pubmed
DTHybrid score Not Available

Enzymes


Cytochrome P450 1A1
Name Cytochrome P450 1A1
Gene Name CYP1A1
Actions inducer
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.2317

Transporters


Solute carrier family 22 member 6
Name Solute carrier family 22 member 6
Gene Name SLC22A6
Actions inhibitor
References
  • Lu R, Chan BS, Schuster VL: Cloning of the human kidney PAH transporter: narrow substrate specificity and regulation by protein kinase C. Am J Physiol. 1999 Feb;276(2 Pt 2):F295-303. - Pubmed
DTHybrid score 0.3151
Bile salt export pump
Name Bile salt export pump
Gene Name ABCB11
Actions substrate
References
  • Wang EJ, Casciano CN, Clement RP, Johnson WW: Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites. Pharm Res. 2003 Apr;20(4):537-44. - Pubmed
DTHybrid score 0.2191
Multidrug resistance-associated protein 1
Name Multidrug resistance-associated protein 1
Gene Name ABCC1
Actions substrate
References
  • Sun H, Johnson DR, Finch RA, Sartorelli AC, Miller DW, Elmquist WF: Transport of fluorescein in MDCKII-MRP1 transfected cells and mrp1-knockout mice. Biochem Biophys Res Commun. 2001 Jun 22;284(4):863-9. - Pubmed
DTHybrid score 0.2408

Predictions


Id Partner name Gene Name Score
4512 Cytochrome P450 3A4 CYP3A4 0.1303
6307 Ig gamma-2 chain C region IGHG2 0.1273
1588 Multidrug resistance protein 1 ABCB1 0.1217
6338 Ig kappa chain C region IGKC 0.118
4785 Ig gamma-1 chain C region IGHG1 0.1071
4200 Cytochrome P450 1A2 CYP1A2 0.1055
4757 Cytochrome P450 2C9 CYP2C9 0.0848
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0834
6142 Solute carrier family 22 member 8 SLC22A8 0.0815
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0787
4119 Cytochrome P450 2D6 CYP2D6 0.074
4118 Cytochrome P450 3A5 CYP3A5 0.0729
4924 Cytochrome P450 2C8 CYP2C8 0.0685
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.065
6016 Cytochrome P450 2C19 CYP2C19 0.0608
1024 Solute carrier family 22 member 11 SLC22A11 0.058
6013 Cytochrome P450 2E1 CYP2E1 0.0526
587 Serum albumin ALB 0.0506
6107 Cytochrome P450 3A7 CYP3A7 0.0479
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0461
6143 Solute carrier family 22 member 7 SLC22A7 0.0455
1898 Cytochrome P450 1B1 CYP1B1 0.0453
6141 Sodium/bile acid cotransporter SLC10A1 0.0448
6030 Cytochrome P450 2B6 CYP2B6 0.0396
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0389
20 Prostaglandin G/H synthase 1 PTGS1 0.0372
2164 Multidrug resistance-associated protein 4 ABCC4 0.037
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0368
5718 Cytochrome P450 2A6 CYP2A6 0.0358
118 Organic cation/carnitine transporter 2 SLC22A5 0.0338
290 Prostaglandin G/H synthase 2 PTGS2 0.0334
6144 Solute carrier family 22 member 2 SLC22A2 0.0331
817 DNA topoisomerase 2-alpha TOP2A 0.0329
6145 Solute carrier family 22 member 1 SLC22A1 0.0323
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0314
6148 Multidrug resistance-associated protein 7 ABCC10 0.0309
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0292
6137 Multidrug resistance-associated protein 6 ABCC6 0.025
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0248
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.022
404 DNA gyrase subunit A gyrA 0.0212
6224 DNA gyrase subunit A gyrA 0.0212
6147 Solute carrier family 22 member 3 SLC22A3 0.0212
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0197
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0188
136 Estrogen receptor ESR1 0.0177
738 Monocarboxylate transporter 1 SLC16A1 0.0177
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0174
833 Organic cation/carnitine transporter 1 SLC22A4 0.0173
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0172
468 Cytochrome P450 4A11 CYP4A11 0.0168
2404 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PIK3CG 0.0164
683 Potassium transporter GK0582 0.0156
6106 Cytochrome P450 2C18 CYP2C18 0.0151
592 Carbonic anhydrase 4 CA4 0.015
295 Carbonic anhydrase 1 CA1 0.0149
633 Penicillin-binding proteins 1A/1B pbpA 0.0149
887 DNA gyrase subunit B gyrB 0.0146
4150 DNA gyrase subunit B gyrB 0.0146
6225 DNA gyrase subunit B gyrB 0.0146
3671 7-alpha-hydroxysteroid dehydrogenase hdhA 0.0146
6012 Tryptophan 2,3-dioxygenase TDO2 0.0145
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0144
723 Cytosolic phospholipase A2 PLA2G4A 0.0143
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0139
161 Tubulin beta chain TUBB 0.0138
312 Tubulin beta chain TUB2 0.0138
477 DNA topoisomerase 4 subunit A parC 0.0138
886 DNA topoisomerase 4 subunit A parC 0.0138
6226 DNA topoisomerase 4 subunit A parC 0.0138
731 HIV-1 protease HIV-1 protease 0.0137
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0135
6136 Multidrug resistance-associated protein 5 ABCC5 0.0134
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0133
2808 Chloramphenicol acetyltransferase 3 cat3 0.0132
3307 Acriflavine resistance protein B acrB 0.013
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0129
2449 Tubulin alpha-3 chain TUBA1A 0.0128
33 Cystine/glutamate transporter SLC7A11 0.0123
308 30S ribosomal protein S12 rpsL 0.0122
6704 30S ribosomal protein S12 rpsL 0.0122
357 Carbonic anhydrase 2 CA2 0.0122
380 Cytochrome P450 17A1 CYP17A1 0.012
3270 Elongation factor G fusA 0.0119
2331 HTH-type transcriptional regulator qacR qacR 0.0118
6461 HTH-type transcriptional regulator qacR qacR 0.0118
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0117
338 DNA polymerase UL30 0.0116
379 DNA polymerase UL54 0.0116
697 DNA polymerase ORF28 0.0116
2482 DNA polymerase 43 0.0116
4104 DNA polymerase BALF5 0.0116
48 Pyridoxal kinase PDXK 0.0116
3811 Cytochrome P450 19A1 CYP19A1 0.0116
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0115
49 Endothelin B receptor EDNRB 0.0113
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0113
4790 Glycosyltransferase GtfA gtfA 0.011
578 Endothelin-1 receptor EDNRA 0.0106
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0104
3639 Thymidine phosphorylase deoA 0.0103
3936 Thymidine phosphorylase TYMP 0.0103
6014 Cytochrome P450 2A13 CYP2A13 0.0102
6167 Organic solute transporter subunit beta OSTB 0.0101
6166 Organic solute transporter subunit alpha OSTA 0.01
645 Penicillin-binding protein 1A mrcA 0.01
5805 Penicillin-binding protein 1A ponA 0.01
6185 Penicillin-binding protein 1A mrcA 0.01
6799 Penicillin-binding protein 1A pbpA 0.01
6599 HTH-type transcriptional regulator ttgR ttgR 0.01
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0097
373 Transthyretin TTR 0.0096
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0096
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0096
6058 Geranylgeranyl pyrophosphate synthetase GGPS1 0.0095
5849 cAMP-dependent protein kinase type I-alpha regulatory subunit PRKAR1A 0.0092
853 Farnesyl pyrophosphate synthetase FDPS 0.0092
6126 Carbonic anhydrase 7 CA7 0.0092
588 Chromodomain-helicase-DNA-binding protein 1 CHD1 0.0091
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0091
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0091
1244 Low-density lipoprotein receptor-related protein 2 LRP2 0.009
871 Glucocorticoid receptor NR3C1 0.0089
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0089
3932 Glutathione S-transferase A2 GSTA2 0.0087
29 Tubulin beta-1 chain TUBB1 0.0085
492 Histamine H1 receptor HRH1 0.0085
605 Fumarate reductase flavoprotein subunit frdA 0.0083
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0083
3673 Fumarate reductase flavoprotein subunit fccA 0.0083
4912 Fumarate reductase flavoprotein subunit ifcA 0.0083
6549 Fumarate reductase flavoprotein subunit frdA 0.0083
273 Apoptosis regulator Bcl-2 BCL2 0.0083
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0083
3947 Xanthine dehydrogenase/oxidase XDH 0.0082
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0082
2016 Dipeptidase 1 DPEP1 0.0082
461 Glycine receptor subunit alpha-3 GLRA3 0.0081
5626 Nucleoside diphosphate kinase B NME2 0.0081
1629 Transcription factor AP-1 JUN 0.0079
2499 Tubulin beta-2C chain TUBB2C 0.0079
777 Tumor necrosis factor TNF 0.0077
6212 Tubulin gamma-1 chain TUBG1 0.0077
6210 Tubulin delta chain TUBD1 0.0077
6211 Tubulin epsilon chain TUBE1 0.0077
4192 DNA topoisomerase 2-beta TOP2B 0.0077
543 Penicillin-binding protein 1B mrcB 0.0077
6186 Penicillin-binding protein 1B ponB 0.0077
6822 Penicillin-binding protein 1b pbp1b 0.0077
6844 Penicillin-binding protein 1b pbp1b 0.0077
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0077
4120 NADPH--cytochrome P450 reductase POR 0.0076
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0075
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0073
613 Atrial natriuretic peptide receptor A NPR1 0.0072
22 30S ribosomal protein S4 rpsD 0.0072
6714 30S ribosomal protein S4 rpsD 0.0072
3587 Gastrotropin FABP6 0.0072
3806 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A 0.0071
5923 Microtubule-associated protein tau MAPT 0.0071
5924 Microtubule-associated protein 4 MAP4 0.0071
6031 Cytochrome P450 3A43 CYP3A43 0.007
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0069
140 30S ribosomal protein S9 rpsI 0.0068
6719 30S ribosomal protein S9 rpsI 0.0068
6725 30S ribosomal protein S9 rpsI 0.0068
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0068
193 Beta-1 adrenergic receptor ADRB1 0.0067
1517 Beta-3 adrenergic receptor ADRB3 0.0067
4604 Liver carboxylesterase 1 CES1 0.0067
6043 Putative G-protein coupled receptor 44 GPR44 0.0067
614 Progesterone receptor PGR 0.0066
844 Epidermal growth factor receptor EGFR 0.0066
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0066
5294 Nucleoside diphosphate kinase A NME1 0.0066
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0066
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0066
1852 Microtubule-associated protein 2 MAP2 0.0065
3917 Methylenetetrahydrofolate reductase MTHFR 0.0065
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0064
183 Vascular endothelial growth factor A VEGFA 0.0063
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0063
2539 Tubulin alpha-1 chain TUBA4A 0.0063
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0063
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0063
1757 Myeloperoxidase MPO 0.0062
1050 Bile salt sulfotransferase SULT2A1 0.0062
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0062
5787 Angiopoietin-1 receptor TEK 0.0061
1714 Mitogen-activated protein kinase 3 MAPK3 0.0061
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.006
132 ATP-binding cassette sub-family A member 1 ABCA1 0.006
6149 Solute carrier family 22 member 10 SLC22A10 0.006
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0059
2320 Thymidine kinase, cytosolic TK1 0.0059
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0059
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0059
558 Solute carrier family 12 member 1 SLC12A1 0.0059
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0058
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0058
790 DNA polymerase subunit alpha B POLA2 0.0058
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0058
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0058
131 Synaptic vesicular amine transporter SLC18A2 0.0057
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0057
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0057
275 Arachidonate 5-lipoxygenase ALOX5 0.0056
1010 Cytochrome P450 51A1 CYP51A1 0.0056
766 Beta-2 adrenergic receptor ADRB2 0.0056
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0056
3426 Glutamine synthetase glnA 0.0055
3987 Glutamine synthetase GLUL 0.0055
466 Solute carrier family 12 member 3 SLC12A3 0.0055
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0054
80 Peroxisome proliferator-activated receptor alpha PPARA 0.0054
6085 Fatty acid-binding protein, intestinal FABP2 0.0054
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0054
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0054
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0053
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.0053
1192 Sulfotransferase 1A1 SULT1A1 0.0052
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0052
438 Taste receptor type 1 member 2 TAS1R2 0.0051
253 Sodium/potassium-transporting ATPase gamma chain FXYD2 0.0051
3809 Estrogen-related receptor gamma ESRRG 0.0051
820 Glycine receptor subunit alpha-2 GLRA2 0.005
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0049
24 Thymidylate synthase TMP1 0.0049
359 Thymidylate synthase TYMS 0.0049
2626 Thymidylate synthase thyA 0.0049
2729 Thymidylate synthase thyA 0.0049
5352 Thymidylate synthase THYA 0.0049
277 Purine nucleoside phosphorylase PNP 0.0049
2870 Purine nucleoside phosphorylase punA 0.0049
2945 Purine nucleoside phosphorylase punA 0.0049
4659 Purine nucleoside phosphorylase TM_1596 0.0049
4825 Purine nucleoside phosphorylase TTHA1435 0.0049
6131 Carbonic anhydrase 14 CA14 0.0048
1638 Solute carrier family 2, facilitated glucose transporter member 2 SLC2A2 0.0048
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0047
869 Estrogen receptor beta ESR2 0.0047
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0047
952 Dipeptidyl peptidase 4 DPP4 0.0047
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0046
3686 Acyl-CoA thioesterase I precursor tesA 0.0045
823 Fibroblast growth factor receptor 2 FGFR2 0.0045
5934 Cytochrome P450 26A1 CYP26A1 0.0045
6122 Carbonic anhydrase 3 CA3 0.0045
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0045
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0045
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0044
1820 Beta-nerve growth factor NGF 0.0044
146 Androgen receptor AR 0.0044
4228 Keratin, type II cytoskeletal 7 KRT7 0.0044
3007 Carbonic anhydrase 12 CA12 0.0044
4205 Carbonic anhydrase 9 CA9 0.0044
6220 Aryl hydrocarbon receptor AHR 0.0043
84 Nuclear receptor 0B1 NR0B1 0.0043
4773 Deoxycytidine kinase DCK 0.0043
5698 Riboflavin synthase alpha chain ribE 0.0043
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0042
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0042
115 Penicillin-binding protein 2 mrdA 0.0041
6069 Penicillin-binding protein 2 mrdA 0.0041
6118 Penicillin-binding protein 2 penA 0.0041
6187 Penicillin-binding protein 2 pbpA 0.0041
6686 Penicillin-binding protein 2 pbp2 0.0041
6939 Penicillin-binding protein 2 mrdA 0.0041
7163 Penicillin-binding protein 2 pbpA 0.0041
408 Riboflavin kinase RFK 0.0041
318 Alpha-2A adrenergic receptor ADRA2A 0.0041
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0041
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0041
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.004
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.004
6766 O-GlcNAcase BT_4395 BT_4395 0.004
1558 Transient receptor potential cation channel subfamily V member 1 TRPV1 0.004
2981 Phospholipase A2, membrane associated PLA2G2A 0.004
7 Nitric oxide synthase, inducible NOS2 0.0039
267 Plasminogen activator inhibitor 1 SERPINE1 0.0039
737 Mineralocorticoid receptor NR3C2 0.0039
4146 Phosphatidylinositol 3-kinase regulatory subunit gamma PIK3R3 0.0039
4145 Phosphatidylinositol 3-kinase regulatory subunit beta PIK3R2 0.0039
293 Gamma-glutamyl hydrolase GGH 0.0039
1 Peptidoglycan synthetase ftsI ftsI 0.0038
4155 Peptidoglycan synthetase ftsI ftsI 0.0038
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0038
341 5-hydroxytryptamine 3 receptor HTR3A 0.0038
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0038
1176 Mitogen-activated protein kinase 1 MAPK1 0.0038
4238 50S ribosomal protein L4 rplD 0.0037
5578 50S ribosomal protein L4 rplD 0.0037
6173 50S ribosomal protein L4 rplD 0.0037
6219 50S ribosomal protein L4 rplD 0.0037
5353 Glutamate decarboxylase alpha gadA 0.0037
6138 Multidrug resistance protein 3 ABCB4 0.0037
831 D(2) dopamine receptor DRD2 0.0037
556 Alpha-1A adrenergic receptor ADRA1A 0.0036
677 Choline-phosphate cytidylyltransferase A PCYT1A 0.0036
244 Angiotensin-converting enzyme ACE 0.0036
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0035
6221 Steroid hormone receptor ERR1 ESRRA 0.0035
889 3-oxoacyl-[acyl-carrier-protein] synthase 1 fabB 0.0035
6860 3-oxoacyl-[acyl-carrier-protein] synthase 1 kasA 0.0035
2391 Ferrochelatase hemH 0.0035
6502 Ferrochelatase DKFZp686P18130 0.0035
1591 Ferrochelatase, mitochondrial FECH 0.0035
4237 50S ribosomal protein L22 rplV 0.0035
908 Glutathione S-transferase theta-1 GSTT1 0.0035
2216 Fibroblast growth factor receptor 4 FGFR4 0.0035
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0034
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0034
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0034
1650 Heme carrier protein 1 SLC46A1 0.0034
6168 Solute carrier family 22 member 16 SLC22A16 0.0034
4203 Histamine N-methyltransferase HNMT 0.0034
751 Potassium channel subfamily K member 6 KCNK6 0.0034
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0034
2236 Casein kinase II subunit alpha CSNK2A1 0.0034
992 Protein tyrosine kinase 2 beta PTK2B 0.0034
65 Matrix metalloproteinase-9 Not Available 0.0033
1281 Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 0.0033
632 Alpha-1B adrenergic receptor ADRA1B 0.0033
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0033
702 UMP-CMP kinase CMPK1 0.0033
332 Beta-lactamase blaZ 0.0033
2478 Beta-lactamase ampC 0.0033
2613 Beta-lactamase ampC 0.0033
2635 Beta-lactamase ampC 0.0033
2700 Beta-lactamase penP 0.0033
5445 Beta-lactamase blaB 0.0033
6019 Beta-lactamase SHV-7 0.0033
6701 Beta-lactamase cphA 0.0033
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0033
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0033
489 Monocarboxylate transporter 2 SLC16A7 0.0032
3941 Amine oxidase [flavin-containing] A MAOA 0.0032
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0032
504 Mast/stem cell growth factor receptor KIT 0.0032
476 RAC-alpha serine/threonine-protein kinase AKT1 0.0032
2021 Thrombomodulin THBD 0.0031
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0031
320 5-hydroxytryptamine 1A receptor HTR1A 0.0031
284 DNA-directed RNA polymerase beta chain rpoB 0.0031
5773 DNA-directed RNA polymerase beta chain rpoB 0.0031
465 Calmodulin CALM1 0.0031
172 Potassium channel subfamily K member 1 KCNK1 0.0031
342 P protein [Includes: DNA-directed DNA polymerase P 0.0031
612 P protein [Includes: DNA-directed DNA polymerase P 0.0031
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0031
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.003
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.003
23 D(1A) dopamine receptor DRD1 0.003
517 Alcohol dehydrogenase 1C ADH1C 0.003
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.003
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.003
3856 Fibroblast growth factor receptor 3 FGFR3 0.003
6495 Cytochrome c oxidase subunit 7C, mitochondrial COX7C 0.003
6493 Cytochrome c oxidase subunit 6C COX6C 0.003
6494 Cytochrome c oxidase subunit 7B, mitochondrial COX7B 0.003
6497 Cytochrome c oxidase subunit 6A2, mitochondrial COX6A2 0.003
6499 Cytochrome c oxidase polypeptide 7A1, mitochondrial COX7A1 0.003
6498 Cytochrome c oxidase subunit 6B1 COX6B1 0.003
6496 Cytochrome c oxidase subunit 8A, mitochondrial COX8A 0.003
6491 Cytochrome c oxidase subunit 5A, mitochondrial COX5A 0.003
6489 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial COX4I1 0.003
6490 Cytochrome c oxidase subunit 3 MT-CO3 0.003
5793 Cytochrome c oxidase subunit 2 MT-CO2 0.003
6559 Cytochrome c oxidase subunit 2 ctaC 0.003
6669 Cytochrome c oxidase subunit 2 ctaC 0.003
371 Cytochrome c oxidase subunit 1 MT-CO1 0.003
6558 Cytochrome c oxidase subunit 1 ctaD 0.003
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.003
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.003
2112 Toll-like receptor 9 TLR9 0.0029
654 Flavin reductase BLVRB 0.0029
822 Aldose reductase AKR1B1 0.0029
3923 Cholinesterase BCHE 0.0029
469 Annexin A1 ANXA1 0.0029
502 5-hydroxytryptamine 2A receptor HTR2A 0.0029
3688 Branched-chain-amino-acid aminotransferase ilvE 0.0028
4252 Penicillin-binding protein 5 dacA 0.0028
484 Tyrosine-protein kinase ABL2 ABL2 0.0028
159 Penicillin-binding protein 2B penA 0.0028
6121 Penicillin-binding protein 2B penA 0.0028
260 Cytochrome P450 51 ERG11 0.0028
761 Cytochrome P450 51 ERG11 0.0028
3163 Cytochrome P450 51 cyp51 0.0028
1867 Major prion protein PRNP 0.0028
904 Glutathione S-transferase P GSTP1 0.0028
6146 High affinity copper uptake protein 1 SLC31A1 0.0028
2540 Choloylglycine hydrolase cbh 0.0027
1025 Aquaporin-1 AQP1 0.0027
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0027
4311 tRNA TRDMT1 0.0027
4325 tRNA trmD 0.0027
4328 tRNA trmD 0.0027
3685 Catabolite gene activator crp 0.0027
4655 Adenylate cyclase cyaC 0.0027
4759 Adenylate cyclase cyaB2 0.0027
106 Cannabinoid receptor 2 CNR2 0.0026
6218 Pannexin-1 PANX1 0.0026
6824 Tyrosine-protein kinase Lyn LYN 0.0026
6836 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial HIBCH 0.0026
6837 Serine/threonine-protein kinase 17B STK17B 0.0026
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0026
6501 Fatty acid-binding protein, liver FABP1 0.0026
130 Prostacyclin synthase PTGIS 0.0025
509 Thymidine kinase TK 0.0025
570 Thymidine kinase TK 0.0025
2559 Thymidine kinase TK 0.0025
3430 Thymidine kinase tdk 0.0025
3518 Thymidine kinase TK 0.0025
5301 Thymidine kinase tdk 0.0025
5771 Thymidine kinase ORF36 0.0025
7009 Thymidine kinase ORF36 0.0025
824 Sodium-dependent serotonin transporter SLC6A4 0.0025
1313 Lactoylglutathione lyase GLO1 0.0025
707 72 kDa type IV collagenase MMP2 0.0025
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0025
68 Cannabinoid receptor 1 CNR1 0.0025
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0024
6207 30S ribosomal protein S14 rpsN 0.0024
6209 30S ribosomal protein S19 rpsS 0.0024
6712 30S ribosomal protein S19 rpsS 0.0024
6726 30S ribosomal protein S19 rpsS 0.0024
165 FL cytokine receptor FLT3 0.0024
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0024
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0024
6228 Nuclear receptor coactivator 1 NCOA1 0.0024
471 Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) SLC6A14 0.0024
569 Retinal dehydrogenase 2 ALDH1A2 0.0024
16 Adenosine A1 receptor ADORA1 0.0024
6241 Nuclear receptor coactivator 2 NCOA2 0.0024
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0024
1178 Adenosine A2a receptor ADORA2A 0.0023
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0023
5818 Folate receptor alpha FOLR1 0.0023
6042 Prostaglandin reductase 2 PTGR2 0.0023
1569 G1/S-specific cyclin-D1 CCND1 0.0023
2249 Aspartate aminotransferase aspC 0.0023
2671 Aspartate aminotransferase aspC 0.0023
5490 Aspartate aminotransferase Not Available 0.0023
76 Nitric-oxide synthase, brain NOS1 0.0023
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0023
6656 UDP-glucuronosyltransferase 3A1 UGT3A1 0.0023
4760 Mll3241 protein mll3241 0.0023
102 DNA topoisomerase I, mitochondrial TOP1MT 0.0023
6020 Aldehyde oxidase AOX1 0.0023
921 Glutamate receptor 2 GRIA2 0.0022
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0022
611 Retinal dehydrogenase 1 ALDH1A1 0.0022
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0022
997 Protein kinase C beta type PRKCB 0.0022
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.0022
1792 Tissue-type plasminogen activator PLAT 0.0022
1275 Estrogen sulfotransferase SULT1E1 0.0022
124 Histamine H2 receptor HRH2 0.0021
6500 Phospholipase A2 PLA2G1B 0.0021
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.0021
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.0021
1196 Complement decay-accelerating factor CD55 0.0021
6033 High affinity interleukin-8 receptor A CXCR1 0.0021
718 Folate receptor gamma FOLR3 0.0021
299 Folate receptor beta FOLR2 0.0021
804 Mitochondrial folate transporter/carrier SLC25A32 0.0021
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.0021
634 Squalene monooxygenase SQLE 0.0021
7196 Squalene monooxygenase ERG1 0.0021
1198 Serum paraoxonase/arylesterase 1 PON1 0.0021
6223 Penicillin-binding protein 1C pbpC 0.0021
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0021
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0021
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0021
527 Prostacyclin receptor PTGIR 0.0021
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0021
1970 Protein kinase C alpha type PRKCA 0.0021
6102 Arylamine N-acetyltransferase 2 NAT2 0.0021
340 Apoptotic protease-activating factor 1 APAF1 0.0021
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.002
672 Prostaglandin F2-alpha receptor PTGFR 0.002
590 5-hydroxytryptamine 2C receptor HTR2C 0.002
291 Nitric-oxide synthase, endothelial NOS3 0.002
2408 Tyrosine-protein kinase SYK SYK 0.002
2599 Tyrosine-protein kinase HCK HCK 0.002
606 Cytochrome P450 27, mitochondrial CYP27A1 0.002
867 Penicillin-binding protein 3 pbpC 0.0019
6119 Penicillin-binding protein 3 pbp3 0.0019
7154 Penicillin-binding protein 3 pbp3 0.0019
7157 Penicillin-binding protein 3 LMHCC_2184 0.0019
7162 Penicillin-binding protein 3 pbpB 0.0019
7172 Penicillin-binding protein 3 pbp3 0.0019
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0019
581 Cytochrome P450 2R1 CYP2R1 0.0019
122 P2Y purinoceptor 12 P2RY12 0.0019
407 Vascular endothelial growth factor receptor 2 KDR 0.0019
1353 DNA topoisomerase 1 TOP1 0.0019
3552 DNA topoisomerase 1 topA 0.0019
1654 Interleukin-1 beta IL1B 0.0019
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0019
6343 ATP synthase subunit beta, mitochondrial ATP5B 0.0019
6342 ATP synthase subunit alpha, mitochondrial ATP5A1 0.0019
6344 ATP synthase subunit gamma, mitochondrial ATP5C1 0.0019
3830 Calreticulin CALR 0.0018
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0018
2105 ATP-binding cassette sub-family G member 1 ABCG1 0.0018
745 Anti-Muellerian hormone type-2 receptor AMHR2 0.0018
825 Arsenical pump-driving ATPase ASNA1 0.0018
3435 Arsenical pump-driving ATPase arsA 0.0018
154 AFG3-like protein 2 AFG3L2 0.0018
486 Serine/threonine-protein kinase ALS2CR7 CDK15 0.0018
225 NEDD8-activating enzyme E1 regulatory subunit NAE1 0.0018
510 Serine/threonine-protein kinase receptor R3 ACVRL1 0.0018
733 Activin receptor type 1B ACVR1B 0.0018
483 A-Raf proto-oncogene serine/threonine-protein kinase ARAF 0.0018
21 Beta-adrenergic receptor kinase 2 ADRBK2 0.0018
377 Beta-adrenergic receptor kinase 1 ADRBK1 0.0018
395 ALK tyrosine kinase receptor Not Available 0.0018
1992 Vitamin D-binding protein GC 0.0018
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0018
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0018
53 Solute carrier family 12 member 5 SLC12A5 0.0018
663 Solute carrier family 12 member 4 SLC12A4 0.0018
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0017
6034 Hydroxyindole O-methyltransferase ASMT 0.0017
6035 Nuclear receptor ROR-beta RORB 0.0017
6036 Eosinophil peroxidase EPX 0.0017
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0017
976 Platelet glycoprotein IX GP9 0.0017
2417 Chloramphenicol acetyltransferase cat 0.0017
3278 Chloramphenicol acetyltransferase cat 0.0017
2810 Dr hemagglutinin structural subunit draA 0.0017
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0017
400 Coagulation factor IX F9 0.0017
5461 Coagulation factor IX F9 0.0017
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.0017
1374 Natriuretic peptides B NPPB 0.0017
1827 Gap junction alpha-1 protein GJA1 0.0017
1908 Vascular cell adhesion protein 1 VCAM1 0.0017
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0017
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0017
292 Activin receptor type-1 ACVR1 0.0017
849 Activated CDC42 kinase 1 TNK2 0.0017
310 Solute carrier family 12 member 2 SLC12A2 0.0017
3810 Catechol O-methyltransferase COMT 0.0017
935 Proto-oncogene tyrosine-protein kinase Yes YES1 0.0016
1063 Signal transducer and activator of transcription 5B STAT5B 0.0016
4103 Proteasome subunit beta type 2 PSMB2 0.0016
4102 Proteasome subunit beta type 5 PSMB5 0.0016
6259 (3R)-hydroxymyristoyl-acyl carrier protein dehydratase fabZ 0.0016
4101 Proteasome subunit beta type 1 PSMB1 0.0016
896 Glutathione S-transferase Mu 1 GSTM1 0.0016
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.0016
821 Acetyl-coenzyme A synthetase 2-like, mitochondrial ACSS1 0.0016
704 Long-chain-fatty-acid--CoA ligase 1 ACSL1 0.0016
386 Acetyl-coenzyme A synthetase, cytoplasmic ACSS2 0.0016
297 Adenylate cyclase type 1 ADCY1 0.0016
459 Retinoic acid receptor RXR-alpha RXRA 0.0016
814 Ryanodine receptor 1 RYR1 0.0016
289 Cytosolic purine 5'-nucleotidase NT5C2 0.0016
6182 Cytochrome P450 2J2 CYP2J2 0.0016
378 Alpha-2C adrenergic receptor ADRA2C 0.0016
629 Alpha-2B adrenergic receptor ADRA2B 0.0016
4081 Vitamin K epoxide reductase complex subunit 1-like protein 1 VKORC1L1 0.0015
604 Vitamin K-dependent protein Z PROZ 0.0015
494 Caspase-1 CASP1 0.0015
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.0015
765 Indoleamine 2,3-dioxygenase IDO1 0.0015
251 Alcohol dehydrogenase 1A ADH1A 0.0015
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0015
748 5'-AMP-activated protein kinase catalytic subunit alpha-1 PRKAA1 0.0015
1507 Cytochrome c CYCS 0.0015
1405 Thiopurine S-methyltransferase TPMT 0.0015
885 5-hydroxytryptamine 1B receptor HTR1B 0.0014
770 Retinoic acid-induced protein 3 GPRC5A 0.0014
719 Retinoic acid receptor responder protein 1 RARRES1 0.0014
934 Proto-oncogene tyrosine-protein kinase Fyn FYN 0.0014
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0014
268 Adenosine A2b receptor ADORA2B 0.0014
422 Vitamin K-dependent protein C PROC 0.0014
1245 Vitamin K-dependent protein S PROS1 0.0014
4217 Telomerase reverse transcriptase TERT 0.0014
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0014
571 Melatonin receptor type 1A MTNR1A 0.0014
362 Melatonin receptor type 1B MTNR1B 0.0014
3760 Penicillin-binding protein 5 precursor dacA 0.0014
638 D(3) dopamine receptor DRD3 0.0014
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0013
740 Argininosuccinate synthase ASS1 0.0013
865 Argininosuccinate synthase ASS1 0.0013
2680 Argininosuccinate synthase argG 0.0013
3194 Argininosuccinate synthase argG 0.0013
936 Ephrin type-A receptor 2 EPHA2 0.0013
856 Vitamin D3 receptor VDR 0.0013
661 ADP/ATP translocase 1 SLC25A4 0.0013
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.0013
444 Alcohol dehydrogenase 1B ADH1B 0.0013
6021 Adenosine kinase ADK 0.0013
6184 D-alanyl-D-alanine carboxypeptidase dacC dacC 0.0013
561 Retinol-binding protein II, cellular RBP2 0.0013
35 Dehydrogenase/reductase SDR family member 4 DHRS4 0.0013
4073 Retinol dehydrogenase 11 RDH11 0.0013
4074 Retinol dehydrogenase 14 RDH14 0.0013
1097 Lecithin retinol acyltransferase LRAT 0.0013
589 Retinoid-binding protein 7 RBP7 0.0013
753 Retinol-binding protein III, cellular RBP5 0.0013
4071 Short-chain dehydrogenase/reductase 3 DHRS3 0.0013
4075 Photoreceptor outer segment all-trans retinol dehydrogenase RDH8 0.0013
863 Cellular retinaldehyde-binding protein RLBP1 0.0013
800 Retinol dehydrogenase 12 RDH12 0.0013
282 Interphotoreceptor retinoid-binding protein RBP3 0.0013
651 Retinol dehydrogenase 13 RDH13 0.0013
4072 All-trans-retinol 13,14-reductase RETSAT 0.0013
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0013
2077 Caspase-3 CASP3 0.0013
756 Sex hormone-binding globulin SHBG 0.0013
242 Asparagine synthetase [glutamine-hydrolyzing] ASNS 0.0013
365 Dihydrofolate reductase DHFR 0.0013
2381 Dihydrofolate reductase DFR1 0.0013
2833 Dihydrofolate reductase Not Available 0.0013
2931 Dihydrofolate reductase folA 0.0013
3544 Dihydrofolate reductase folA 0.0013
3682 Dihydrofolate reductase folA 0.0013
6642 Dihydrofolate reductase folA 0.0013
6756 Dihydrofolate reductase dfrA 0.0013
6163 Copper-transporting ATPase 2 ATP7B 0.0013
6165 Copper-transporting ATPase 1 ATP7A 0.0013
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0012
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0012
819 Penicillin-binding protein 4 dacB 0.0012
482 Glycine receptor subunit alpha-1 GLRA1 0.0012
228 Beta platelet-derived growth factor receptor PDGFRB 0.0012
789 Alpha-1D adrenergic receptor ADRA1D 0.0012
4122 Histone deacetylase 2 HDAC2 0.0012
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0012
331 Retinol-binding protein I, cellular RBP1 0.0012
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0012
627 11-cis retinol dehydrogenase RDH5 0.0011
640 Aldehyde dehydrogenase 1A3 ALDH1A3 0.0011
2461 D-alanyl-D-alanine carboxypeptidase Not Available 0.0011
5756 D-alanyl-D-alanine carboxypeptidase dac 0.0011
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0011
798 Osteocalcin BGLAP 0.0011
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0011
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0011
70 Type-1 angiotensin II receptor AGTR1 0.001
780 Retinoic acid receptor RXR-gamma RXRG 0.001
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.001
369 Coagulation factor VII F7 0.001
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.001
3937 Fatty-acid amide hydrolase FAAH 0.001
345 Plasma retinol-binding protein RBP4 0.001
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.001
1928 Leukotriene C4 synthase LTC4S 0.001
4043 Glutaredoxin-2, mitochondrial GLRX2 0.001
4034 Glutaredoxin-1 GLRX 0.001
910 Epididymal secretory glutathione peroxidase GPX5 0.001
4036 Glutathione peroxidase 6 GPX6 0.001
4037 Hypothetical protein GPX1 0.001
4297 Hypothetical protein SP_1951 0.001
4521 Hypothetical protein BC_2969 0.001
4540 Hypothetical protein TM_1070 0.001
4555 Hypothetical protein MT1739 0.001
4569 Hypothetical protein mshD 0.001
4578 Hypothetical protein PA3270 0.001
4747 Hypothetical protein PA3967 0.001
5177 Hypothetical protein TM_0096 0.001
5194 Hypothetical protein PA1204 0.001
5240 Hypothetical protein Rv2991 0.001
5370 Hypothetical protein TM_1158 0.001
5710 Hypothetical protein Tb927.5.1360 0.001
4029 Microsomal glutathione S-transferase 3 MGST3 0.001
900 Glutathione S-transferase A4 GSTA4 0.001
4030 Thioredoxin domain-containing protein 12 TXNDC12 0.001
911 Glutathione peroxidase 3 GPX3 0.001
4040 Glutathione peroxidase 7 GPX7 0.001
907 Glutathione peroxidase 2 GPX2 0.001
4032 Microsomal glutathione S-transferase 1 MGST1 0.001
906 Glutathione peroxidase 1 GPX1 0.001
4039 CDNA FLJ23636 fis, clone CAS07176 GPX8 0.001
4035 Glutathione S-transferase Mu 5 GSTM5 0.001
903 Glutathione S-transferase A5 GSTA5 0.001
4042 Glutathione transferase omega-2 GSTO2 0.001
4033 S-formylglutathione hydrolase ESD 0.001
4038 Glutathione peroxidase 4 GPX4 0.001
1975 Phospholipid hydroperoxide glutathione peroxidase, mitochondrial GPX4 0.001
1056 Gamma-glutamyltranspeptidase 1 GGT1 0.001
1039 Histone deacetylase 9 HDAC9 0.0009
88 Retinoic acid receptor RXR-beta RXRB 0.0009
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0009
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0009
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0009
3957 Adenosine deaminase ADA 0.0009
162 Retinoic acid receptor gamma-1 RARG 0.0009
3319 Hydroxyacylglutathione hydrolase HAGH 0.0009
898 Glutathione S-transferase A3 GSTA3 0.0009
6002 Prostaglandin E2 receptor EP4 subtype PTGER4 0.0009
897 Glutathione S-transferase kappa 1 GSTK1 0.0009
909 Maleylacetoacetate isomerase GSTZ1 0.0009
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.0009
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.0008
899 Glutathione S-transferase Mu 3 GSTM3 0.0008
905 Glutathione transferase omega-1 GSTO1 0.0008
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0008
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0008
4131 Prostaglandin E2 receptor, EP3 subtype PTGER3 0.0008
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0008
4041 Microsomal glutathione S-transferase 2 MGST2 0.0008
406 Prostaglandin E2 receptor, EP2 subtype PTGER2 0.0008
2165 Glutathione S-transferase Mu 2 GSTM2 0.0008
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0008
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0008
239 Coagulation factor X F10 0.0008
207 Glutathione synthetase GSS 0.0008
5269 Glutathione synthetase gshB 0.0008
901 Glutathione S-transferase Mu 4 GSTM4 0.0007
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0007
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0007
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0007
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0007
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0007
4031 Glutathione S-transferase A1 GSTA1 0.0007
164 Histamine H4 receptor HRH4 0.0007
714 Glutathione reductase, mitochondrial GSR 0.0006
54 Prothrombin F2 0.0006
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0006
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0006
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0006
528 5-hydroxytryptamine 1E receptor HTR1E 0.0005
3939 Amine oxidase [flavin-containing] B MAOB 0.0005
1256 5-hydroxytryptamine 6 receptor HTR6 0.0005
716 5-hydroxytryptamine 7 receptor HTR7 0.0005
432 D(4) dopamine receptor DRD4 0.0004
725 5-hydroxytryptamine 1D receptor HTR1D 0.0004
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0004
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0004
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0003
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