DT-Web

DB08846 - Ellagic Acid


Identification
Name Ellagic Acid
Accession Number DB08846
Type small molecule
Description Ellagic acid is present in several fruits such as cranberries, strawberries, raspberries, and pomegranates. In pomegranates, there are several therapeutic compounds but ellagic acid is the most active and abundant. Ellagic acid is also present in vegetables. Ellagic acid is an investigational drug studied for treatment of Follicular Lymphoma (phase 2 trial), protection from brain injury of intrauterine growth restricted babies (phase 1 and 2 trial), improvement of cardiovascular function in adolescents who are obese (phase 2 trial), and topical treatment of solar lentigines. Ellagic acid's therapeutic action mostly involves antioxidant and anti-proliferative effects.
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 302.1926
Groups Not Available
Monoisotopic Weight 302.006267168
Pharmacology
Indication Ellagic acid is being investigated for use in follicular lymphoma, brain injury in intrauterine growth restricted babies, obese adolescents, and solar lentigines.
Mechanism of action The exact mechanism of action of ellagic acid in its different potential indications is still being investigated.
Absorption After oral consumption, ellagic acid reaches maximum concentrations in about 1 hour.
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Carbonic anhydrase 1
Name Carbonic anhydrase 1
Gene Name CA1
Pharmacological action unknown
Actions inhibitor
References
  • Innocenti A, Beyza Ozturk Sarikaya S, Gulcin I, Supuran CT: Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids. Bioorg Med Chem. 2010 Mar 15;18(6):2159-64. doi: 10.1016/j.bmc.2010.01.076. Epub 2010 Feb 6. - Pubmed
DTHybrid score 1.1394
Carbonic anhydrase 2
Name Carbonic anhydrase 2
Gene Name CA2
Pharmacological action unknown
Actions inhibitor
References
  • Innocenti A, Beyza Ozturk Sarikaya S, Gulcin I, Supuran CT: Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids. Bioorg Med Chem. 2010 Mar 15;18(6):2159-64. doi: 10.1016/j.bmc.2010.01.076. Epub 2010 Feb 6. - Pubmed
DTHybrid score 2.2067
Carbonic anhydrase 3
Name Carbonic anhydrase 3
Gene Name CA3
Pharmacological action unknown
Actions inhibitor
References
  • Innocenti A, Beyza Ozturk Sarikaya S, Gulcin I, Supuran CT: Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids. Bioorg Med Chem. 2010 Mar 15;18(6):2159-64. doi: 10.1016/j.bmc.2010.01.076. Epub 2010 Feb 6. - Pubmed
DTHybrid score 0.4482
Carbonic anhydrase 4
Name Carbonic anhydrase 4
Gene Name CA4
Pharmacological action unknown
Actions inhibitor
References
  • Innocenti A, Beyza Ozturk Sarikaya S, Gulcin I, Supuran CT: Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids. Bioorg Med Chem. 2010 Mar 15;18(6):2159-64. doi: 10.1016/j.bmc.2010.01.076. Epub 2010 Feb 6. - Pubmed
DTHybrid score 0.966
Carbonic anhydrase 5A, mitochondrial
Name Carbonic anhydrase 5A, mitochondrial
Gene Name CA5A
Pharmacological action unknown
Actions inhibitor
References
  • Innocenti A, Beyza Ozturk Sarikaya S, Gulcin I, Supuran CT: Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids. Bioorg Med Chem. 2010 Mar 15;18(6):2159-64. doi: 10.1016/j.bmc.2010.01.076. Epub 2010 Feb 6. - Pubmed
DTHybrid score 0.6194
Carbonic anhydrase 5B, mitochondrial
Name Carbonic anhydrase 5B, mitochondrial
Gene Name CA5B
Pharmacological action unknown
Actions inhibitor
References
  • Innocenti A, Beyza Ozturk Sarikaya S, Gulcin I, Supuran CT: Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids. Bioorg Med Chem. 2010 Mar 15;18(6):2159-64. doi: 10.1016/j.bmc.2010.01.076. Epub 2010 Feb 6. - Pubmed
DTHybrid score 0.3435
Carbonic anhydrase 6
Name Carbonic anhydrase 6
Gene Name CA6
Pharmacological action unknown
Actions inhibitor
References
  • Innocenti A, Beyza Ozturk Sarikaya S, Gulcin I, Supuran CT: Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids. Bioorg Med Chem. 2010 Mar 15;18(6):2159-64. doi: 10.1016/j.bmc.2010.01.076. Epub 2010 Feb 6. - Pubmed
DTHybrid score Not Available
Carbonic anhydrase 7
Name Carbonic anhydrase 7
Gene Name CA7
Pharmacological action unknown
Actions inhibitor
References
  • Innocenti A, Beyza Ozturk Sarikaya S, Gulcin I, Supuran CT: Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids. Bioorg Med Chem. 2010 Mar 15;18(6):2159-64. doi: 10.1016/j.bmc.2010.01.076. Epub 2010 Feb 6. - Pubmed
DTHybrid score 0.5903
Carbonic anhydrase 9
Name Carbonic anhydrase 9
Gene Name CA9
Pharmacological action unknown
Actions inhibitor
References
  • Innocenti A, Beyza Ozturk Sarikaya S, Gulcin I, Supuran CT: Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids. Bioorg Med Chem. 2010 Mar 15;18(6):2159-64. doi: 10.1016/j.bmc.2010.01.076. Epub 2010 Feb 6. - Pubmed
DTHybrid score 0.5816
Carbonic anhydrase 12
Name Carbonic anhydrase 12
Gene Name CA12
Pharmacological action unknown
Actions inhibitor
References
  • Innocenti A, Beyza Ozturk Sarikaya S, Gulcin I, Supuran CT: Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids. Bioorg Med Chem. 2010 Mar 15;18(6):2159-64. doi: 10.1016/j.bmc.2010.01.076. Epub 2010 Feb 6. - Pubmed
DTHybrid score 0.5819
Carbonic anhydrase 14
Name Carbonic anhydrase 14
Gene Name CA14
Pharmacological action unknown
Actions inhibitor
References
  • Innocenti A, Beyza Ozturk Sarikaya S, Gulcin I, Supuran CT: Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids. Bioorg Med Chem. 2010 Mar 15;18(6):2159-64. doi: 10.1016/j.bmc.2010.01.076. Epub 2010 Feb 6. - Pubmed
DTHybrid score 0.4892
Casein kinase II subunit alpha
Name Casein kinase II subunit alpha
Gene Name CSNK2A1
Pharmacological action unknown
Actions inhibitor
References
  • Sekiguchi Y, Nakaniwa T, Kinoshita T, Nakanishi I, Kitaura K, Hirasawa A, Tsujimoto G, Tada T: Structural insight into human CK2alpha in complex with the potent inhibitor ellagic acid. Bioorg Med Chem Lett. 2009 Jun 1;19(11):2920-3. doi: 10.1016/j.bmcl.2009.04.076. Epub 2009 Apr 22. - Pubmed
  • Cozza G, Bonvini P, Zorzi E, Poletto G, Pagano MA, Sarno S, Donella-Deana A, Zagotto G, Rosolen A, Pinna LA, Meggio F, Moro S: Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application. J Med Chem. 2006 Apr 20;49(8):2363-6. - Pubmed
DTHybrid score 1.786
cAMP-dependent protein kinase catalytic subunit alpha
Name cAMP-dependent protein kinase catalytic subunit alpha
Gene Name PRKACA
Pharmacological action unknown
Actions inhibitor, competitive
References
  • Wang BH, Lu ZX, Polya GM: Inhibition of eukaryote serine/threonine-specific protein kinases by piceatannol. Planta Med. 1998 Apr;64(3):195-9. - Pubmed
DTHybrid score 1.1349
Protein kinase C alpha type
Name Protein kinase C alpha type
Gene Name PRKCA
Pharmacological action unknown
Actions inhibitor, competitive
References
  • Wang BH, Lu ZX, Polya GM: Inhibition of eukaryote serine/threonine-specific protein kinases by piceatannol. Planta Med. 1998 Apr;64(3):195-9. - Pubmed
DTHybrid score 0.4837
Protein kinase C beta type
Name Protein kinase C beta type
Gene Name PRKCB
Pharmacological action unknown
Actions inhibitor, competitive
References
  • Wang BH, Lu ZX, Polya GM: Inhibition of eukaryote serine/threonine-specific protein kinases by piceatannol. Planta Med. 1998 Apr;64(3):195-9. - Pubmed
DTHybrid score 0.8441
Tyrosine-protein kinase SYK
Name Tyrosine-protein kinase SYK
Gene Name SYK
Pharmacological action unknown
Actions inhibitor
References
  • Cozza G, Bonvini P, Zorzi E, Poletto G, Pagano MA, Sarno S, Donella-Deana A, Zagotto G, Rosolen A, Pinna LA, Meggio F, Moro S: Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application. J Med Chem. 2006 Apr 20;49(8):2363-6. - Pubmed
DTHybrid score 1.5602
Squalene monooxygenase
Name Squalene monooxygenase
Gene Name SQLE
Pharmacological action unknown
Actions inhibitor
References
  • Abe I, Kashiwagi Y, Noguchi H, Tanaka T, Ikeshiro Y, Kashiwada Y: Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase. J Nat Prod. 2001 Aug;64(8):1010-4. - Pubmed
DTHybrid score 1.062

Enzymes


Cytochrome P450 1A1
Name Cytochrome P450 1A1
Gene Name CYP1A1
Actions inhibitor,inducer
References
  • Gonzalez-Sarrias A, Azorin-Ortuno M, Yanez-Gascon MJ, Tomas-Barberan FA, Garcia-Conesa MT, Espin JC: Dissimilar in vitro and in vivo effects of ellagic acid and its microbiota-derived metabolites, urolithins, on the cytochrome P450 1A1. J Agric Food Chem. 2009 Jun 24;57(12):5623-32. doi: 10.1021/jf900725e. - Pubmed
  • Barch DH, Rundhaugen LM, Thomas PE, Kardos P, Pillay NS: Dietary ellagic acid inhibits the enzymatic activity of CYP1A1 without altering hepatic concentrations of CYP1A1 or CYP1A1 mRNA. Biochem Biophys Res Commun. 1994 Jun 30;201(3):1477-82. - Pubmed
DTHybrid score 0.2857
Cytochrome P450 2E1
Name Cytochrome P450 2E1
Gene Name CYP2E1
Actions inhibitor
References
  • Ahn D, Putt D, Kresty L, Stoner GD, Fromm D, Hollenberg PF: The effects of dietary ellagic acid on rat hepatic and esophageal mucosal cytochromes P450 and phase II enzymes. Carcinogenesis. 1996 Apr;17(4):821-8. - Pubmed
DTHybrid score 0.3068

Transporters


Solute carrier family 22 member 6
Name Solute carrier family 22 member 6
Gene Name SLC22A6
Actions Not Available
References
  • Whitley AC, Sweet DH, Walle T: The dietary polyphenol ellagic acid is a potent inhibitor of hOAT1. Drug Metab Dispos. 2005 Aug;33(8):1097-100. Epub 2005 May 3. - Pubmed
DTHybrid score 0.606
Solute carrier family 22 member 11
Name Solute carrier family 22 member 11
Gene Name SLC22A11
Actions Not Available
References
  • Whitley AC, Sweet DH, Walle T: The dietary polyphenol ellagic acid is a potent inhibitor of hOAT1. Drug Metab Dispos. 2005 Aug;33(8):1097-100. Epub 2005 May 3. - Pubmed
DTHybrid score 0.2911

Predictions


Id Partner name Gene Name Score
7196 Squalene monooxygenase ERG1 1.062
6264 cAMP-dependent protein kinase inhibitor alpha PKIA 0.5205
4512 Cytochrome P450 3A4 CYP3A4 0.2905
466 Solute carrier family 12 member 3 SLC12A3 0.2804
4184 Protein kinase C delta type PRKCD 0.2031
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.1894
4757 Cytochrome P450 2C9 CYP2C9 0.1798
1025 Aquaporin-1 AQP1 0.1708
558 Solute carrier family 12 member 1 SLC12A1 0.16
6016 Cytochrome P450 2C19 CYP2C19 0.1522
6142 Solute carrier family 22 member 8 SLC22A8 0.1512
4200 Cytochrome P450 1A2 CYP1A2 0.1493
4119 Cytochrome P450 2D6 CYP2D6 0.1148
6127 Carbonic anhydrase-related protein CA8 0.1051
6129 Carbonic anhydrase-related protein 11 CA11 0.1051
6128 Carbonic anhydrase-related protein 10 CA10 0.105
6135 Sodium channel subunit beta-4 SCN4B 0.1049
6133 Sodium channel subunit beta-2 SCN2B 0.1049
6134 Sodium channel subunit beta-3 SCN3B 0.1049
6132 Sodium channel subunit beta-1 SCN1B 0.1049
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.1004
6130 Carbonic anhydrase 13 CA13 0.0927
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.092
4924 Cytochrome P450 2C8 CYP2C8 0.0903
20 Prostaglandin G/H synthase 1 PTGS1 0.0897
1588 Multidrug resistance protein 1 ABCB1 0.085
215 Sodium channel protein type 11 subunit alpha SCN11A 0.084
6143 Solute carrier family 22 member 7 SLC22A7 0.0812
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0801
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0772
158 Sodium channel protein type 1 subunit alpha SCN1A 0.077
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0753
1531 Rho-associated protein kinase 1 ROCK1 0.073
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0721
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0704
587 Serum albumin ALB 0.0692
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0646
1405 Thiopurine S-methyltransferase TPMT 0.0596
290 Prostaglandin G/H synthase 2 PTGS2 0.0579
5718 Cytochrome P450 2A6 CYP2A6 0.0573
6020 Aldehyde oxidase AOX1 0.0571
253 Sodium/potassium-transporting ATPase gamma chain FXYD2 0.0571
3941 Amine oxidase [flavin-containing] A MAOA 0.0543
220 Sodium channel protein type 5 subunit alpha SCN5A 0.052
1721 Glycogen synthase kinase-3 beta GSK3B 0.0517
3939 Amine oxidase [flavin-containing] B MAOB 0.0514
4118 Cytochrome P450 3A5 CYP3A5 0.0513
6030 Cytochrome P450 2B6 CYP2B6 0.0505
4077 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform PPP2CB 0.049
375 SEC14-like protein 3 SEC14L3 0.049
86 SEC14-like protein 4 SEC14L4 0.049
4076 Diacylglycerol kinase alpha DGKA 0.049
2116 RAC-beta serine/threonine-protein kinase AKT2 0.047
283 SEC14-like protein 2 SEC14L2 0.046
708 Alpha-tocopherol transfer protein TTPA 0.0456
4078 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform PPP2CA 0.0435
4784 Beta-mannosidase manB 0.0432
6695 Beta-mannosidase BT_0458 0.0432
118 Organic cation/carnitine transporter 2 SLC22A5 0.0396
743 Phosphatidylserine decarboxylase proenzyme PISD 0.0396
1848 Phosphatidylserine synthase 1 PTDSS1 0.0396
4051 Phosphatidylserine synthase 2 PTDSS2 0.0396
211 Scavenger receptor class B member 1 SCARB1 0.0395
4053 Sphingomyelin phosphodiesterase 3 SMPD3 0.0395
4047 Diacylglycerol kinase gamma DGKG 0.0395
4052 Sphingomyelin phosphodiesterase 4 SMPD4 0.0395
1477 Probable phospholipid-transporting ATPase IA ATP8A1 0.0395
4048 Diacylglycerol kinase delta DGKD 0.0395
905 Glutathione transferase omega-1 GSTO1 0.039
899 Glutathione S-transferase Mu 3 GSTM3 0.039
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0388
3932 Glutathione S-transferase A2 GSTA2 0.0386
1898 Cytochrome P450 1B1 CYP1B1 0.037
4531 Putative ketoacyl reductase actIII 0.0365
2530 Protein kinase C theta type PRKCQ 0.0361
275 Arachidonate 5-lipoxygenase ALOX5 0.036
6697 Rho-associated protein kinase 2 ROCK2 0.0359
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0356
6107 Cytochrome P450 3A7 CYP3A7 0.0355
810 Heme oxygenase 1 HMOX1 0.0353
3391 Heme oxygenase 1 pbsA1 0.0353
186 Glutamate--cysteine ligase catalytic subunit GCLC 0.0348
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0347
3811 Cytochrome P450 19A1 CYP19A1 0.0341
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0338
2297 Genome polyprotein Not Available 0.0337
2322 Genome polyprotein Not Available 0.0337
2694 Genome polyprotein Not Available 0.0337
2719 Genome polyprotein Not Available 0.0337
2860 Genome polyprotein Not Available 0.0337
2928 Genome polyprotein Not Available 0.0337
3160 Genome polyprotein Not Available 0.0337
3260 Genome polyprotein Not Available 0.0337
4783 Genome polyprotein Not Available 0.0337
5726 Genome polyprotein Not Available 0.0337
5779 Genome polyprotein Not Available 0.0337
5867 Genome polyprotein Not Available 0.0337
6253 Genome polyprotein Not Available 0.0337
6301 Genome polyprotein Not Available 0.0337
6380 Genome polyprotein Not Available 0.0337
6381 Genome polyprotein Not Available 0.0337
6437 Genome polyprotein Not Available 0.0337
6520 Genome polyprotein Not Available 0.0337
6521 Genome polyprotein Not Available 0.0337
6652 Genome polyprotein Not Available 0.0337
6734 Genome polyprotein Not Available 0.0337
6735 Genome polyprotein Not Available 0.0337
6736 Genome polyprotein Not Available 0.0337
6737 Genome polyprotein Not Available 0.0337
6738 Genome polyprotein Not Available 0.0337
6739 Genome polyprotein Not Available 0.0337
6744 Genome polyprotein Not Available 0.0337
6748 Genome polyprotein Not Available 0.0337
6894 Genome polyprotein Not Available 0.0337
6898 Genome polyprotein Not Available 0.0337
2164 Multidrug resistance-associated protein 4 ABCC4 0.0336
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0333
2998 Sialic acid-binding Ig-like lectin 7 SIGLEC7 0.0325
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0322
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.032
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0319
2398 Tyrosine-protein kinase ZAP-70 ZAP70 0.0317
2473 Tyrosine-protein kinase CSK CSK 0.0313
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0313
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0308
3437 Eosinophil lysophospholipase CLC 0.0303
904 Glutathione S-transferase P GSTP1 0.0302
4787 Envelope glycoprotein gp160 env 0.0295
4820 Envelope glycoprotein gp160 env 0.0295
5727 Envelope glycoprotein gp160 env 0.0295
2207 Rhodopsin RHO 0.0289
6259 (3R)-hydroxymyristoyl-acyl carrier protein dehydratase fabZ 0.0282
862 Multidrug resistance-associated protein 1 ABCC1 0.0278
776 Bile salt export pump ABCB11 0.0276
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0273
6144 Solute carrier family 22 member 2 SLC22A2 0.0272
3480 Mannan endo-1,4-beta-mannosidase manA 0.0262
22 30S ribosomal protein S4 rpsD 0.0256
6714 30S ribosomal protein S4 rpsD 0.0256
310 Solute carrier family 12 member 2 SLC12A2 0.0246
140 30S ribosomal protein S9 rpsI 0.0241
6719 30S ribosomal protein S9 rpsI 0.0241
6725 30S ribosomal protein S9 rpsI 0.0241
3428 H(+)/Cl(-) exchange transporter clcA clcA 0.0239
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0236
6145 Solute carrier family 22 member 1 SLC22A1 0.0235
633 Penicillin-binding proteins 1A/1B pbpA 0.0231
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0229
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0223
64 Neuraminidase NA 0.022
641 Neuraminidase NA 0.022
2676 Neuraminidase NA 0.022
3026 Neuraminidase NA 0.022
3519 Neuraminidase NA 0.022
6007 Neuraminidase NA 0.022
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0218
3426 Glutamine synthetase glnA 0.0218
3987 Glutamine synthetase GLUL 0.0218
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0209
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0209
6296 Serine/threonine-protein kinase haspin GSG2 0.0208
2511 MAP kinase-activated protein kinase 2 MAPKAPK2 0.0206
3623 Divalent-cation tolerance protein cutA cutA 0.0206
3382 Glycolipid transfer protein GLTP 0.0192
2404 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PIK3CG 0.019
4785 Ig gamma-1 chain C region IGHG1 0.0187
833 Organic cation/carnitine transporter 1 SLC22A4 0.0183
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0182
738 Monocarboxylate transporter 1 SLC16A1 0.018
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0178
438 Taste receptor type 1 member 2 TAS1R2 0.0178
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0172
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0168
6106 Cytochrome P450 2C18 CYP2C18 0.0166
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0163
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0159
468 Cytochrome P450 4A11 CYP4A11 0.0158
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0158
645 Penicillin-binding protein 1A mrcA 0.0158
5805 Penicillin-binding protein 1A ponA 0.0158
6185 Penicillin-binding protein 1A mrcA 0.0158
6799 Penicillin-binding protein 1A pbpA 0.0158
3686 Acyl-CoA thioesterase I precursor tesA 0.0157
373 Transthyretin TTR 0.0156
3923 Cholinesterase BCHE 0.0156
404 DNA gyrase subunit A gyrA 0.0156
6224 DNA gyrase subunit A gyrA 0.0156
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0153
2889 Kallikrein-6 KLK6 0.0149
2947 Trypsin sprT 0.0149
492 Histamine H1 receptor HRH1 0.0147
6012 Tryptophan 2,3-dioxygenase TDO2 0.0145
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0143
6141 Sodium/bile acid cotransporter SLC10A1 0.0142
6147 Solute carrier family 22 member 3 SLC22A3 0.0142
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.014
6882 Iodotyrosine dehalogenase 1 IYD 0.0138
6881 Nickel-binding periplasmic protein nikA 0.0137
6880 Alpha-amylase G-6 BH0413 0.0137
1558 Transient receptor potential cation channel subfamily V member 1 TRPV1 0.0137
543 Penicillin-binding protein 1B mrcB 0.0135
6186 Penicillin-binding protein 1B ponB 0.0135
6822 Penicillin-binding protein 1b pbp1b 0.0135
6844 Penicillin-binding protein 1b pbp1b 0.0135
3226 UPF0234 protein HI1034 HI_1034 0.0135
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0134
3384 Macrophage migration inhibitory factor MIF 0.0132
4814 Copper transport protein ATOX1 ATOX1 0.013
136 Estrogen receptor ESR1 0.013
3211 3,2-trans-enoyl-CoA isomerase, mitochondrial DCI 0.013
3011 Suppressor of tumorigenicity protein 14 ST14 0.013
5353 Glutamate decarboxylase alpha gadA 0.0129
613 Atrial natriuretic peptide receptor A NPR1 0.0129
6136 Multidrug resistance-associated protein 5 ABCC5 0.0125
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0125
6014 Cytochrome P450 2A13 CYP2A13 0.0124
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0124
308 30S ribosomal protein S12 rpsL 0.0122
6704 30S ribosomal protein S12 rpsL 0.0122
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0121
889 3-oxoacyl-[acyl-carrier-protein] synthase 1 fabB 0.012
6860 3-oxoacyl-[acyl-carrier-protein] synthase 1 kasA 0.012
442 Envelope glycoprotein gp41 0.012
4859 Envelope glycoprotein env 0.012
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0119
777 Tumor necrosis factor TNF 0.0118
2240 Cell division protein kinase 2 CDK2 0.0117
338 DNA polymerase UL30 0.0116
379 DNA polymerase UL54 0.0116
697 DNA polymerase ORF28 0.0116
2482 DNA polymerase 43 0.0116
4104 DNA polymerase BALF5 0.0116
48 Pyridoxal kinase PDXK 0.0116
3176 Trypsin-1 PRSS1 0.0114
332 Beta-lactamase blaZ 0.0113
2478 Beta-lactamase ampC 0.0113
2613 Beta-lactamase ampC 0.0113
2635 Beta-lactamase ampC 0.0113
2700 Beta-lactamase penP 0.0113
5445 Beta-lactamase blaB 0.0113
6019 Beta-lactamase SHV-7 0.0113
6701 Beta-lactamase cphA 0.0113
6149 Solute carrier family 22 member 10 SLC22A10 0.0111
4790 Glycosyltransferase GtfA gtfA 0.011
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.0109
3105 M-phase inducer phosphatase 2 CDC25B 0.0108
4751 Mitogen-activated protein kinase 12 MAPK12 0.0105
115 Penicillin-binding protein 2 mrdA 0.0104
6069 Penicillin-binding protein 2 mrdA 0.0104
6118 Penicillin-binding protein 2 penA 0.0104
6187 Penicillin-binding protein 2 pbpA 0.0104
6686 Penicillin-binding protein 2 pbp2 0.0104
6939 Penicillin-binding protein 2 mrdA 0.0104
7163 Penicillin-binding protein 2 pbpA 0.0104
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0103
3639 Thymidine phosphorylase deoA 0.0103
3936 Thymidine phosphorylase TYMP 0.0103
6148 Multidrug resistance-associated protein 7 ABCC10 0.0103
790 DNA polymerase subunit alpha B POLA2 0.0103
723 Cytosolic phospholipase A2 PLA2G4A 0.0102
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0102
1867 Major prion protein PRNP 0.01
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0099
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0099
2886 Trypsin-3 PRSS3 0.0098
3688 Branched-chain-amino-acid aminotransferase ilvE 0.0098
260 Cytochrome P450 51 ERG11 0.0098
761 Cytochrome P450 51 ERG11 0.0098
3163 Cytochrome P450 51 cyp51 0.0098
1 Peptidoglycan synthetase ftsI ftsI 0.0097
4155 Peptidoglycan synthetase ftsI ftsI 0.0097
6339 Ig kappa chain V-II region RPMI 6410 Not Available 0.0097
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0097
16 Adenosine A1 receptor ADORA1 0.0094
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0093
5849 cAMP-dependent protein kinase type I-alpha regulatory subunit PRKAR1A 0.0092
4750 Protein S100-A11 S100A11 0.0092
817 DNA topoisomerase 2-alpha TOP2A 0.0091
1244 Low-density lipoprotein receptor-related protein 2 LRP2 0.009
465 Calmodulin CALM1 0.009
1757 Myeloperoxidase MPO 0.009
1176 Mitogen-activated protein kinase 1 MAPK1 0.0089
130 Prostacyclin synthase PTGIS 0.0088
3917 Methylenetetrahydrofolate reductase MTHFR 0.0088
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0087
6207 30S ribosomal protein S14 rpsN 0.0086
6209 30S ribosomal protein S19 rpsS 0.0086
6712 30S ribosomal protein S19 rpsS 0.0086
6726 30S ribosomal protein S19 rpsS 0.0086
65 Matrix metalloproteinase-9 Not Available 0.0086
2320 Thymidine kinase, cytosolic TK1 0.0085
1638 Solute carrier family 2, facilitated glucose transporter member 2 SLC2A2 0.0084
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0084
605 Fumarate reductase flavoprotein subunit frdA 0.0083
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0083
3673 Fumarate reductase flavoprotein subunit fccA 0.0083
4912 Fumarate reductase flavoprotein subunit ifcA 0.0083
6549 Fumarate reductase flavoprotein subunit frdA 0.0083
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0083
2016 Dipeptidase 1 DPEP1 0.0082
477 DNA topoisomerase 4 subunit A parC 0.008
886 DNA topoisomerase 4 subunit A parC 0.008
6226 DNA topoisomerase 4 subunit A parC 0.008
3482 Cell division protein kinase 7 CDK7 0.008
540 Sodium-dependent noradrenaline transporter SLC6A2 0.008
3005 Threonine-phosphate decarboxylase cobD 0.008
2249 Aspartate aminotransferase aspC 0.008
2671 Aspartate aminotransferase aspC 0.008
5490 Aspartate aminotransferase Not Available 0.008
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0079
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0079
2499 Tubulin beta-2C chain TUBB2C 0.0079
556 Alpha-1A adrenergic receptor ADRA1A 0.0079
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0078
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0078
824 Sodium-dependent serotonin transporter SLC6A4 0.0078
341 5-hydroxytryptamine 3 receptor HTR3A 0.0078
482 Glycine receptor subunit alpha-1 GLRA1 0.0078
193 Beta-1 adrenergic receptor ADRB1 0.0077
24 Thymidylate synthase TMP1 0.0076
359 Thymidylate synthase TYMS 0.0076
2626 Thymidylate synthase thyA 0.0076
2729 Thymidylate synthase thyA 0.0076
5352 Thymidylate synthase THYA 0.0076
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0076
183 Vascular endothelial growth factor A VEGFA 0.0075
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0075
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0075
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0075
6031 Cytochrome P450 3A43 CYP3A43 0.0075
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0075
6033 High affinity interleukin-8 receptor A CXCR1 0.0074
80 Peroxisome proliferator-activated receptor alpha PPARA 0.0074
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0073
1074 Urokinase-type plasminogen activator PLAU 0.0073
1198 Serum paraoxonase/arylesterase 1 PON1 0.0073
6223 Penicillin-binding protein 1C pbpC 0.0073
527 Prostacyclin receptor PTGIR 0.0073
318 Alpha-2A adrenergic receptor ADRA2A 0.0072
2449 Tubulin alpha-3 chain TUBA1A 0.0072
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0072
315 Arginase-1 ARG1 0.0072
1178 Adenosine A2a receptor ADORA2A 0.0072
6043 Putative G-protein coupled receptor 44 GPR44 0.0072
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0071
6766 O-GlcNAcase BT_4395 BT_4395 0.0071
3806 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A 0.0071
672 Prostaglandin F2-alpha receptor PTGFR 0.0071
831 D(2) dopamine receptor DRD2 0.0071
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.0069
1010 Cytochrome P450 51A1 CYP51A1 0.0069
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0068
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0068
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0068
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.0068
3627 UPF0190 protein yedY yedY 0.0067
1392 Catenin beta-1 CTNNB1 0.0067
3352 Structural polyprotein Not Available 0.0067
3628 Structural polyprotein Not Available 0.0067
4892 Structural polyprotein Not Available 0.0067
867 Penicillin-binding protein 3 pbpC 0.0067
6119 Penicillin-binding protein 3 pbp3 0.0067
7154 Penicillin-binding protein 3 pbp3 0.0067
7157 Penicillin-binding protein 3 LMHCC_2184 0.0067
7162 Penicillin-binding protein 3 pbpB 0.0067
7172 Penicillin-binding protein 3 pbp3 0.0067
1517 Beta-3 adrenergic receptor ADRB3 0.0067
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0067
766 Beta-2 adrenergic receptor ADRB2 0.0065
1654 Interleukin-1 beta IL1B 0.0065
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0065
502 5-hydroxytryptamine 2A receptor HTR2A 0.0065
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0064
6102 Arylamine N-acetyltransferase 2 NAT2 0.0063
241 Calcium-transporting ATPase type 2C member 1 ATP2C1 0.0063
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0063
4199 Sphingosine 1-phosphate receptor Edg-8 S1PR5 0.0063
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0062
53 Solute carrier family 12 member 5 SLC12A5 0.0061
663 Solute carrier family 12 member 4 SLC12A4 0.0061
6167 Organic solute transporter subunit beta OSTB 0.0061
6166 Organic solute transporter subunit alpha OSTA 0.0061
1714 Mitogen-activated protein kinase 3 MAPK3 0.0061
820 Glycine receptor subunit alpha-2 GLRA2 0.0061
293 Gamma-glutamyl hydrolase GGH 0.0061
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.006
5626 Nucleoside diphosphate kinase B NME2 0.006
537 ATP synthase delta chain, mitochondrial ATP5D 0.0059
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.0059
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.0059
6137 Multidrug resistance-associated protein 6 ABCC6 0.0058
23 D(1A) dopamine receptor DRD1 0.0058
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.0057
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.0057
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0057
6085 Fatty acid-binding protein, intestinal FABP2 0.0057
1422 Serine/threonine-protein kinase 6 AURKA 0.0057
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0056
444 Alcohol dehydrogenase 1B ADH1B 0.0056
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0056
705 Glutamate receptor 1 GRIA1 0.0056
251 Alcohol dehydrogenase 1A ADH1A 0.0056
871 Glucocorticoid receptor NR3C1 0.0056
3947 Xanthine dehydrogenase/oxidase XDH 0.0055
5691 DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE RMLC rmlC 0.0055
3361 Serpin B5 SERPINB5 0.0055
5694 Transcription antiterminator licT licT 0.0055
590 5-hydroxytryptamine 2C receptor HTR2C 0.0054
6220 Aryl hydrocarbon receptor AHR 0.0054
1650 Heme carrier protein 1 SLC46A1 0.0053
494 Caspase-1 CASP1 0.0053
2981 Phospholipase A2, membrane associated PLA2G2A 0.0052
1507 Cytochrome c CYCS 0.005
4604 Liver carboxylesterase 1 CES1 0.005
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0049
1192 Sulfotransferase 1A1 SULT1A1 0.0049
277 Purine nucleoside phosphorylase PNP 0.0049
2870 Purine nucleoside phosphorylase punA 0.0049
2945 Purine nucleoside phosphorylase punA 0.0049
4659 Purine nucleoside phosphorylase TM_1596 0.0049
4825 Purine nucleoside phosphorylase TTHA1435 0.0049
5294 Nucleoside diphosphate kinase A NME1 0.0048
3760 Penicillin-binding protein 5 precursor dacA 0.0048
3810 Catechol O-methyltransferase COMT 0.0048
4217 Telomerase reverse transcriptase TERT 0.0048
4542 Glutaminase 1 glsA1 0.0047
4544 Glutaminase 1 glsA1 0.0047
33 Cystine/glutamate transporter SLC7A11 0.0046
320 5-hydroxytryptamine 1A receptor HTR1A 0.0046
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0046
2514 Phosphocarrier protein HPr ptsH 0.0046
5689 Phosphocarrier protein HPr ptsH 0.0046
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0046
4534 Cytohesin-2 CYTH2 0.0046
3602 Anti-sigma F factor antagonist spoIIAA 0.0046
5686 Potassium voltage-gated channel subfamily C member 4 KCNC4 0.0046
6184 D-alanyl-D-alanine carboxypeptidase dacC dacC 0.0046
4122 Histone deacetylase 2 HDAC2 0.0045
2077 Caspase-3 CASP3 0.0045
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0044
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0044
1820 Beta-nerve growth factor NGF 0.0044
146 Androgen receptor AR 0.0044
4228 Keratin, type II cytoskeletal 7 KRT7 0.0044
632 Alpha-1B adrenergic receptor ADRA1B 0.0043
819 Penicillin-binding protein 4 dacB 0.0043
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0043
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0043
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0043
517 Alcohol dehydrogenase 1C ADH1C 0.0043
2230 Catalase CAT 0.0043
3249 Catalase katA 0.0043
3625 Catalase katA 0.0043
4539 Catalase katA 0.0043
4941 Catalase katB 0.0043
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.0043
5698 Riboflavin synthase alpha chain ribE 0.0043
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0042
2286 Isocitrate dehydrogenase [NADP] icd 0.0042
2302 Isocitrate dehydrogenase [NADP] icd 0.0042
2771 Isocitrate dehydrogenase [NADP] icd 0.0042
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0042
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0041
408 Riboflavin kinase RFK 0.0041
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0041
718 Folate receptor gamma FOLR3 0.004
299 Folate receptor beta FOLR2 0.004
804 Mitochondrial folate transporter/carrier SLC25A32 0.004
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.004
1130 Lithostathine 1 alpha REG1A 0.004
885 5-hydroxytryptamine 1B receptor HTR1B 0.004
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.004
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0039
2021 Thrombomodulin THBD 0.0039
638 D(3) dopamine receptor DRD3 0.0039
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0039
3823 Cytokine receptor common gamma chain IL2RG 0.0039
2461 D-alanyl-D-alanine carboxypeptidase Not Available 0.0039
5756 D-alanyl-D-alanine carboxypeptidase dac 0.0039
380 Cytochrome P450 17A1 CYP17A1 0.0039
4146 Phosphatidylinositol 3-kinase regulatory subunit gamma PIK3R3 0.0039
4145 Phosphatidylinositol 3-kinase regulatory subunit beta PIK3R2 0.0039
3668 Maltose-binding periplasmic protein precursor malE 0.0038
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0038
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0038
823 Fibroblast growth factor receptor 2 FGFR2 0.0038
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0038
4192 DNA topoisomerase 2-beta TOP2B 0.0038
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0037
869 Estrogen receptor beta ESR2 0.0037
3119 Fimbrial protein pilE1 0.0037
4318 Siroheme synthase cysG 0.0037
6146 High affinity copper uptake protein 1 SLC31A1 0.0037
789 Alpha-1D adrenergic receptor ADRA1D 0.0037
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0037
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0037
244 Angiotensin-converting enzyme ACE 0.0036
461 Glycine receptor subunit alpha-3 GLRA3 0.0035
4311 tRNA TRDMT1 0.0035
4325 tRNA trmD 0.0035
4328 tRNA trmD 0.0035
3453 Alkaline phosphatase phoA 0.0035
2852 DNA mismatch repair protein mutL mutL 0.0034
844 Epidermal growth factor receptor EGFR 0.0034
724 Interleukin-2 receptor alpha chain IL2RA 0.0034
717 Interleukin-2 receptor subunit beta IL2RB 0.0034
122 P2Y purinoceptor 12 P2RY12 0.0034
2592 Beta-galactosidase lacZ 0.0034
2178 Metabotropic glutamate receptor 5 GRM5 0.0034
936 Ephrin type-A receptor 2 EPHA2 0.0034
4203 Histamine N-methyltransferase HNMT 0.0034
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0034
811 Translocator protein TSPO 0.0034
4116 Dihydropteroate synthetase Not Available 0.0033
1281 Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 0.0033
2503 Phosphomannomutase/phosphoglucomutase algC 0.0033
5150 Endo-1,4-beta-xylanase Y xynY 0.0033
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0033
6218 Pannexin-1 PANX1 0.0033
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0032
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0032
3090 Chitosanase csn 0.0031
4149 Nuclear factor NF-kappa-B p100 subunit NFKB2 0.0031
94 5-hydroxytryptamine 4 receptor HTR4 0.0031
378 Alpha-2C adrenergic receptor ADRA2C 0.0031
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.0031
6002 Prostaglandin E2 receptor EP4 subtype PTGER4 0.0031
1275 Estrogen sulfotransferase SULT1E1 0.0031
365 Dihydrofolate reductase DHFR 0.0031
2381 Dihydrofolate reductase DFR1 0.0031
2833 Dihydrofolate reductase Not Available 0.0031
2931 Dihydrofolate reductase folA 0.0031
3544 Dihydrofolate reductase folA 0.0031
3682 Dihydrofolate reductase folA 0.0031
6642 Dihydrofolate reductase folA 0.0031
6756 Dihydrofolate reductase dfrA 0.0031
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0031
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0031
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.0031
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.0031
3937 Fatty-acid amide hydrolase FAAH 0.0031
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0031
342 P protein [Includes: DNA-directed DNA polymerase P 0.0031
612 P protein [Includes: DNA-directed DNA polymerase P 0.0031
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0031
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0031
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0031
976 Platelet glycoprotein IX GP9 0.003
400 Coagulation factor IX F9 0.003
5461 Coagulation factor IX F9 0.003
1374 Natriuretic peptides B NPPB 0.003
1827 Gap junction alpha-1 protein GJA1 0.003
1908 Vascular cell adhesion protein 1 VCAM1 0.003
84 Nuclear receptor 0B1 NR0B1 0.003
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.003
1050 Bile salt sulfotransferase SULT2A1 0.0029
2112 Toll-like receptor 9 TLR9 0.0029
654 Flavin reductase BLVRB 0.0029
5818 Folate receptor alpha FOLR1 0.0029
4178 DNA repair protein RAD51 homolog 1 RAD51 0.0029
822 Aldose reductase AKR1B1 0.0029
5641 Rod shape-determining protein MreB TM_0588 0.0029
3794 Osmolarity sensor protein envZ envZ 0.0029
5644 Sensor protein phoQ phoQ 0.0029
5643 General secretion pathway protein E epsE 0.0029
5645 DNA topoisomerase 4 subunit B parE 0.0029
6227 DNA topoisomerase 4 subunit B parE 0.0029
5649 Potassium-transporting ATPase B chain kdpB 0.0029
5290 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0029
5638 ATP-dependent hsl protease ATP-binding subunit hslU hslU 0.0029
5642 Chaperone clpB clpB 0.0029
6042 Prostaglandin reductase 2 PTGR2 0.0029
4131 Prostaglandin E2 receptor, EP3 subtype PTGER3 0.0029
908 Glutathione S-transferase theta-1 GSTT1 0.0029
153 Dopamine beta-hydroxylase DBH 0.0029
406 Prostaglandin E2 receptor, EP2 subtype PTGER2 0.0029
4252 Penicillin-binding protein 5 dacA 0.0028
814 Ryanodine receptor 1 RYR1 0.0028
1253 Interferon gamma IFNG 0.0028
159 Penicillin-binding protein 2B penA 0.0028
6121 Penicillin-binding protein 2B penA 0.0028
330 Spermidine synthase SRM 0.0028
3038 Spermidine synthase speE 0.0028
390 Adenosine A3 receptor ADORA3 0.0028
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0028
4081 Vitamin K epoxide reductase complex subunit 1-like protein 1 VKORC1L1 0.0027
604 Vitamin K-dependent protein Z PROZ 0.0027
1792 Tissue-type plasminogen activator PLAT 0.0027
3404 Exotoxin A eta 0.0027
124 Histamine H2 receptor HRH2 0.0027
3685 Catabolite gene activator crp 0.0027
4655 Adenylate cyclase cyaC 0.0027
4759 Adenylate cyclase cyaB2 0.0027
106 Cannabinoid receptor 2 CNR2 0.0026
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0026
273 Apoptosis regulator Bcl-2 BCL2 0.0026
10 Glycogen phosphorylase, liver form PYGL 0.0026
4773 Deoxycytidine kinase DCK 0.0026
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0026
891 Dihydropteroate synthase folP 0.0025
5359 Dihydropteroate synthase folP 0.0025
7175 Dihydropteroate synthase sulI 0.0025
2282 Protein recA recA 0.0025
2315 Protein recA recA 0.0025
2332 Protein recA recA 0.0025
5263 Protein recA recA 0.0025
740 Argininosuccinate synthase ASS1 0.0025
865 Argininosuccinate synthase ASS1 0.0025
2680 Argininosuccinate synthase argG 0.0025
3194 Argininosuccinate synthase argG 0.0025
2867 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE 0.0025
6433 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 PFKFB4 0.0025
5646 Galactokinase GALK1 0.0025
5265 FtsH ftsH 0.0025
3390 Aminoglycoside 3'-phosphotransferase aphA 0.0025
6029 Aminoglycoside 3'-phosphotransferase aphA1 0.0025
5302 TrwB trwB 0.0025
2397 Dihydroxyacetone kinase dhaK 0.0025
509 Thymidine kinase TK 0.0025
570 Thymidine kinase TK 0.0025
2559 Thymidine kinase TK 0.0025
3430 Thymidine kinase tdk 0.0025
3518 Thymidine kinase TK 0.0025
5301 Thymidine kinase tdk 0.0025
5771 Thymidine kinase ORF36 0.0025
7009 Thymidine kinase ORF36 0.0025
756 Sex hormone-binding globulin SHBG 0.0025
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0025
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0025
268 Adenosine A2b receptor ADORA2B 0.0025
422 Vitamin K-dependent protein C PROC 0.0025
1245 Vitamin K-dependent protein S PROS1 0.0025
707 72 kDa type IV collagenase MMP2 0.0025
68 Cannabinoid receptor 1 CNR1 0.0025
921 Glutamate receptor 2 GRIA2 0.0024
334 S-adenosylmethionine synthetase isoform type-2 MAT2A 0.0024
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0024
471 Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) SLC6A14 0.0024
569 Retinal dehydrogenase 2 ALDH1A2 0.0024
629 Alpha-2B adrenergic receptor ADRA2B 0.0024
473 L-lactate dehydrogenase A chain LDHA 0.0024
620 Bifunctional dihydrofolate reductase-thymidylate synthase Not Available 0.0024
2299 UDP-N-acetylmuramate--L-alanine ligase murC 0.0023
3231 Death-associated protein kinase 1 DAPK1 0.0023
5312 Kinesin-like protein KIF1A KIF1A 0.0023
1569 G1/S-specific cyclin-D1 CCND1 0.0023
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0023
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0023
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.0023
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.0023
358 Cystathionine beta-synthase CBS 0.0023
4760 Mll3241 protein mll3241 0.0023
611 Retinal dehydrogenase 1 ALDH1A1 0.0022
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0022
6163 Copper-transporting ATPase 2 ATP7B 0.0022
6165 Copper-transporting ATPase 1 ATP7A 0.0022
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0022
113 S-adenosylmethionine decarboxylase proenzyme AMD1 0.0022
2892 Acetylglutamate kinase argB 0.0022
3550 Acetylglutamate kinase argB 0.0022
2371 Pantothenate kinase coaA 0.0022
2950 Inositol-trisphosphate 3-kinase A ITPKA 0.0022
2615 Chemotaxis protein cheA cheA 0.0022
825 Arsenical pump-driving ATPase ASNA1 0.0022
3435 Arsenical pump-driving ATPase arsA 0.0022
1881 Hexokinase-1 HK1 0.0022
1313 Lactoylglutathione lyase GLO1 0.0022
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0022
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0022
411 Glycine N-methyltransferase GNMT 0.0022
2290 ADP-ribosyl cyclase 2 BST1 0.0022
5934 Cytochrome P450 26A1 CYP26A1 0.0022
3809 Estrogen-related receptor gamma ESRRG 0.0021
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.0021
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.0021
1196 Complement decay-accelerating factor CD55 0.0021
2727 S-adenosylmethionine synthetase metK 0.0021
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0021
489 Monocarboxylate transporter 2 SLC16A7 0.0021
1152 Glycogen phosphorylase, muscle form PYGM 0.0021
887 DNA gyrase subunit B gyrB 0.0021
4150 DNA gyrase subunit B gyrB 0.0021
6225 DNA gyrase subunit B gyrB 0.0021
2817 Phosphoribosylglycinamide formyltransferase 2 purT 0.002
2298 Cytochrome P450-cam camC 0.002
432 D(4) dopamine receptor DRD4 0.002
518 Peroxidase/catalase T katG 0.002
798 Osteocalcin BGLAP 0.002
6832 Serine/threonine-protein kinase SRPK2 SRPK2 0.002
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.002
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.002
606 Cytochrome P450 27, mitochondrial CYP27A1 0.002
751 Potassium channel subfamily K member 6 KCNK6 0.002
725 5-hydroxytryptamine 1D receptor HTR1D 0.0019
1629 Transcription factor AP-1 JUN 0.0019
581 Cytochrome P450 2R1 CYP2R1 0.0019
6316 ADP-ribosylation factor 1 ARF1 0.0019
563 Thyroid peroxidase TPO 0.0019
3126 Poly [ADP-ribose] polymerase 1 PARP1 0.0019
713 Sodium-dependent dopamine transporter SLC6A3 0.0019
6138 Multidrug resistance protein 3 ABCB4 0.0019
958 Insulin-like growth factor 1 receptor IGF1R 0.0019
2808 Chloramphenicol acetyltransferase 3 cat3 0.0019
3830 Calreticulin CALR 0.0018
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0018
369 Coagulation factor VII F7 0.0018
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0018
2251 Thymidylate kinase tmk 0.0018
2254 Thymidylate kinase DTYMK 0.0018
3522 Thymidylate kinase tmk 0.0018
896 Glutathione S-transferase Mu 1 GSTM1 0.0018
6743 Non-fluorescent flavoprotein luxF 0.0018
6753 Apolipoprotein M APOM 0.0018
6752 Guanylyl cyclase-activating protein 1 GUCA1A 0.0018
2528 Fatty acid metabolism regulator protein fadR 0.0018
6740 Fatty acid metabolism regulator protein fadR 0.0018
394 Calcineurin subunit B isoform 1 PPP3R1 0.0018
6751 Gag polyprotein gag 0.0018
6742 Recoverin RCVRN 0.0018
6747 Chalcone/stilbene synthase family protein MT1417 0.0018
6741 Peroxisomal 3,2-trans-enoyl-CoA isomerase PECI 0.0018
6522 Hepatocyte nuclear factor 4-alpha HNF4A 0.0018
6746 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform PPP3CA 0.0018
1256 5-hydroxytryptamine 6 receptor HTR6 0.0018
6749 Polyprotein Not Available 0.0018
172 Potassium channel subfamily K member 1 KCNK1 0.0018
1992 Vitamin D-binding protein GC 0.0018
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0018
476 RAC-alpha serine/threonine-protein kinase AKT1 0.0018
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0018
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0017
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0017
6034 Hydroxyindole O-methyltransferase ASMT 0.0017
6035 Nuclear receptor ROR-beta RORB 0.0017
6036 Eosinophil peroxidase EPX 0.0017
3822 Actin, alpha skeletal muscle ACTA1 0.0017
2417 Chloramphenicol acetyltransferase cat 0.0017
3278 Chloramphenicol acetyltransferase cat 0.0017
2810 Dr hemagglutinin structural subunit draA 0.0017
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0017
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.0017
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0017
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0017
1836 Mitogen-activated protein kinase 10 MAPK10 0.0017
935 Proto-oncogene tyrosine-protein kinase Yes YES1 0.0016
1063 Signal transducer and activator of transcription 5B STAT5B 0.0016
4103 Proteasome subunit beta type 2 PSMB2 0.0016
4102 Proteasome subunit beta type 5 PSMB5 0.0016
4101 Proteasome subunit beta type 1 PSMB1 0.0016
3957 Adenosine deaminase ADA 0.0016
716 5-hydroxytryptamine 7 receptor HTR7 0.0016
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0016
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0016
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0016
207 Glutathione synthetase GSS 0.0016
5269 Glutathione synthetase gshB 0.0016
459 Retinoic acid receptor RXR-alpha RXRA 0.0016
469 Annexin A1 ANXA1 0.0016
3601 Dihydropteroate synthase 1 folP1 0.0016
3807 Dihydropteroate synthase 1 folP1 0.0016
3808 Dihydropteroate synthase 2 folP2 0.0016
6182 Cytochrome P450 2J2 CYP2J2 0.0016
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0016
6527 Lymphocyte antigen 96 LY96 0.0016
5961 Insulin INS 0.0016
6755 Poliovirus receptor PVR 0.0016
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.0015
765 Indoleamine 2,3-dioxygenase IDO1 0.0015
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0015
7 Nitric oxide synthase, inducible NOS2 0.0015
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0015
3913 Glutamic acid decarboxylase GAD65 0.0015
5432 Trafficking protein particle complex subunit 3 TRAPPC3 0.0014
6750 ADP-ribosylation factor 6 ARF6 0.0014
6524 Protein tonB tonB 0.0014
770 Retinoic acid-induced protein 3 GPRC5A 0.0014
719 Retinoic acid receptor responder protein 1 RARRES1 0.0014
29 Tubulin beta-1 chain TUBB1 0.0014
934 Proto-oncogene tyrosine-protein kinase Fyn FYN 0.0014
161 Tubulin beta chain TUBB 0.0014
312 Tubulin beta chain TUB2 0.0014
571 Melatonin receptor type 1A MTNR1A 0.0014
362 Melatonin receptor type 1B MTNR1B 0.0014
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0014
1483 Membrane copper amine oxidase AOC3 0.0014
319 Opioid receptor, sigma 1 OPRS1 0.0014
239 Coagulation factor X F10 0.0014
2616 Ganglioside GM2 activator GM2A 0.0014
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0014
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0014
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0014
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0014
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0014
677 Choline-phosphate cytidylyltransferase A PCYT1A 0.0013
856 Vitamin D3 receptor VDR 0.0013
484 Tyrosine-protein kinase ABL2 ABL2 0.0013
561 Retinol-binding protein II, cellular RBP2 0.0013
35 Dehydrogenase/reductase SDR family member 4 DHRS4 0.0013
4073 Retinol dehydrogenase 11 RDH11 0.0013
4074 Retinol dehydrogenase 14 RDH14 0.0013
1097 Lecithin retinol acyltransferase LRAT 0.0013
589 Retinoid-binding protein 7 RBP7 0.0013
753 Retinol-binding protein III, cellular RBP5 0.0013
4071 Short-chain dehydrogenase/reductase 3 DHRS3 0.0013
4075 Photoreceptor outer segment all-trans retinol dehydrogenase RDH8 0.0013
863 Cellular retinaldehyde-binding protein RLBP1 0.0013
800 Retinol dehydrogenase 12 RDH12 0.0013
282 Interphotoreceptor retinoid-binding protein RBP3 0.0013
651 Retinol dehydrogenase 13 RDH13 0.0013
4072 All-trans-retinol 13,14-reductase RETSAT 0.0013
2435 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0013
6613 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0013
436 5-hydroxytryptamine 2B receptor HTR2B 0.0013
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0013
4210 Toll-like receptor 4 TLR4 0.0013
267 Plasminogen activator inhibitor 1 SERPINE1 0.0012
735 Alanine aminotransferase 1 GPT 0.0012
3904 Alanine aminotransferase 2 GPT2 0.0012
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0012
228 Beta platelet-derived growth factor receptor PDGFRB 0.0012
6432 Transporter snf 0.0012
702 UMP-CMP kinase CMPK1 0.0012
164 Histamine H4 receptor HRH4 0.0012
331 Retinol-binding protein I, cellular RBP1 0.0012
174 Sigma 1-type opioid receptor SIGMAR1 0.0012
864 Gag-Pol polyprotein gag-pol 0.0012
2237 Gag-Pol polyprotein gag-pol 0.0012
2326 Gag-Pol polyprotein gag-pol 0.0012
2451 Gag-Pol polyprotein gag-pol 0.0012
2901 Gag-Pol polyprotein gag-pol 0.0012
3165 Gag-Pol polyprotein gag-pol 0.0012
3722 Gag-Pol polyprotein gag-pol 0.0012
6306 Gag-Pol polyprotein gag-pol 0.0012
6624 Gag-Pol polyprotein gag-pol 0.0012
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0011
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0011
627 11-cis retinol dehydrogenase RDH5 0.0011
640 Aldehyde dehydrogenase 1A3 ALDH1A3 0.0011
54 Prothrombin F2 0.0011
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0011
504 Mast/stem cell growth factor receptor KIT 0.0011
6221 Steroid hormone receptor ERR1 ESRRA 0.0011
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0011
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0011
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0011
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0011
4120 NADPH--cytochrome P450 reductase POR 0.0011
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0011
70 Type-1 angiotensin II receptor AGTR1 0.001
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.001
780 Retinoic acid receptor RXR-gamma RXRG 0.001
3238 Multidrug resistance protein mexA mexA 0.001
3709 Glycerol uptake facilitator protein glpF 0.001
3116 Bacterioferritin bfr 0.001
4906 Bacterioferritin bfr 0.001
4965 Bacterioferritin bfr 0.001
5489 Ribonucleoside-diphosphate reductase 1 subunit beta nrdB 0.001
3173 Enolase eno 0.001
3336 C4-dicarboxylate transport transcriptional regulatory protein dctD dctD 0.001
3393 TGF-beta receptor type-2 TGFBR2 0.001
2427 Ferrichrome-iron receptor fhuA 0.001
345 Plasma retinol-binding protein RBP4 0.001
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.001
768 FK506-binding protein 1A FKBP1A 0.001
6228 Nuclear receptor coactivator 1 NCOA1 0.001
528 5-hydroxytryptamine 1E receptor HTR1E 0.001
1039 Histone deacetylase 9 HDAC9 0.0009
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0009
847 Mu-type opioid receptor OPRM1 0.0009
88 Retinoic acid receptor RXR-beta RXRB 0.0009
1768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit GNG2 0.0009
1571 G protein-activated inward rectifier potassium channel 1 KCNJ3 0.0009
1268 Neuropeptide S receptor NPSR1 0.0009
1581 G protein-activated inward rectifier potassium channel 2 KCNJ6 0.0009
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0009
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0009
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0009
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0009
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0009
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0009
162 Retinoic acid receptor gamma-1 RARG 0.0009
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0009
3191 Histidinol dehydrogenase hisD 0.0009
3221 Cytochrome c4 cc4 0.0009
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0009
731 HIV-1 protease HIV-1 protease 0.0008
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0008
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0008
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0008
4037 Hypothetical protein GPX1 0.0008
4297 Hypothetical protein SP_1951 0.0008
4521 Hypothetical protein BC_2969 0.0008
4540 Hypothetical protein TM_1070 0.0008
4555 Hypothetical protein MT1739 0.0008
4569 Hypothetical protein mshD 0.0008
4578 Hypothetical protein PA3270 0.0008
4747 Hypothetical protein PA3967 0.0008
5177 Hypothetical protein TM_0096 0.0008
5194 Hypothetical protein PA1204 0.0008
5240 Hypothetical protein Rv2991 0.0008
5370 Hypothetical protein TM_1158 0.0008
5710 Hypothetical protein Tb927.5.1360 0.0008
4527 Putative hydrolase ycdX ycdX 0.0008
4536 Transcriptional regulator, IclR family TM_0065 0.0008
2501 Protein ygbM ygbM 0.0008
4545 Molybdopterin-converting factor subunit 2 moaE 0.0008
4522 Arginine N-succinyltransferase subunit alpha astA 0.0008
4106 Guanylate kinase GUK1 0.0008
4516 Guanylate kinase gmk 0.0008
4538 Hypothetical protein VC1899 VC_1899 0.0008
4529 Oxalate decarboxylase oxdC oxdC 0.0008
4514 Citrate lyase beta subunit-like protein citE 0.0008
4781 Citrate lyase beta subunit-like protein DR_1240 0.0008
4526 Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein TM_1223 0.0008
4524 Mannose-6-phosphate isomerase yvyI 0.0008
4535 Glutaconyl-CoA decarboxylase subunit alpha gcdA 0.0008
4547 Iron binding protein FbpA fbpA 0.0008
4548 Gyrase B gyrB 0.0008
4546 Aminotransferase, putative TM_1131 0.0008
658 Para-aminobenzoate synthase component 1 pabB 0.0008
4515 Peripheral plasma membrane protein CASK CASK 0.0008
737 Mineralocorticoid receptor NR3C2 0.0008
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0008
6459 Glycodelin PAEP 0.0008
6073 Potassium channel subfamily K member 9 KCNK9 0.0008
6072 Potassium channel subfamily K member 3 KCNK3 0.0008
1360 Sphingomyelin phosphodiesterase SMPD1 0.0008
4692 A/G-specific adenine glycosylase mutY 0.0008
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0008
3587 Gastrotropin FABP6 0.0008
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.0008
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.0008
4496 C-terminal-binding protein 1 CTBP1 0.0008
614 Progesterone receptor PGR 0.0007
4517 Probable butyrate kinase 2 buk2 0.0007
3261 Signal recognition particle protein ffh 0.0007
4528 Phenazine biosynthesis protein PhzD phzD1 0.0007
6100 BDNF/NT-3 growth factors receptor NTRK2 0.0007
4533 Glyoxalase family protein BC_1747 0.0007
56 Delta-aminolevulinic acid dehydratase ALAD 0.0007
2356 Delta-aminolevulinic acid dehydratase hemB 0.0007
3613 Delta-aminolevulinic acid dehydratase hemB 0.0007
3674 Delta-aminolevulinic acid dehydratase hemB 0.0007
3759 Glutathione S-transferase gst 0.0007
4541 Glutathione S-transferase GST 0.0007
2929 (S)-2-haloacid dehalogenase dhlB 0.0007
2995 (S)-2-haloacid dehalogenase Not Available 0.0007
3237 Beta-lactamase OXA-2 bla 0.0007
4532 Gephyrin GPHN 0.0007
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0007
2802 Endoglucanase G celCCG 0.0007
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0007
2775 Dihydroorotate dehydrogenase pyrD 0.0007
3467 Methylglyoxal synthase mgsA 0.0007
284 DNA-directed RNA polymerase beta chain rpoB 0.0007
5773 DNA-directed RNA polymerase beta chain rpoB 0.0007
3583 6-phosphogluconolactonase pgl 0.0007
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0007
2525 3-phosphoshikimate 1-carboxyvinyltransferase aroA 0.0006
3201 3-phosphoshikimate 1-carboxyvinyltransferase aroA 0.0006
2688 Peptide deformylase def 0.0006
2708 Peptide deformylase def 0.0006
3004 Peptide deformylase def 0.0006
4337 Peptide deformylase def 0.0006
4338 Peptide deformylase def 0.0006
5368 Peptide deformylase def 0.0006
5371 Peptide deformylase def 0.0006
6375 Peptide deformylase def 0.0006
6378 Peptide deformylase def 0.0006
6379 Peptide deformylase def 0.0006
6776 Peptide deformylase def 0.0006
6900 Peptide deformylase def 0.0006
163 D(1B) dopamine receptor DRD5 0.0006
2548 Subtilisin Carlsberg apr 0.0006
1618 High affinity nerve growth factor receptor NTRK1 0.0006
4269 Hypoxanthine-guanine phosphoribosyltransferase, putative HGPRTase 0.0006
760 Fibroblast growth factor 1 FGF1 0.0005
3027 Streptavidin Not Available 0.0005
500 Monocarboxylate transporter 4 SLC16A3 0.0005
291 Nitric-oxide synthase, endothelial NOS3 0.0004
76 Nitric-oxide synthase, brain NOS1 0.0004
5682 Ribonuclease pancreatic RNASE1 0.0004
467 Delta-type opioid receptor OPRD1 0.0004
696 Kappa-type opioid receptor OPRK1 0.0004
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