DT-Web

Plasmepsin-2


Partner ID 3086
Name Plasmepsin-2
Synonyms 5122
Gene name Not Available
General function Involved in aspartic-type endopeptidase activity
Specific function Hydrolysis of the bonds linking certain hydrophobic residues in hemoglobin or globin. Also cleaves small molecules substrates such as Ala-Leu-Glu-Arg-Thr-Phe-|-Phe(NO(2))- Ser-Phe-Pro-Thr
Gene sequence + ...

Not Available
Protein sequence + ...

MDITVREHDFKHGFIKSNSTFDGLNIDNSKNKKKIQKGFQILYVLLFCSVMCGLFYYVYENVWLQRDNEMNEILKNSEHLTIGFKVENAHDRILKTIKTHKLKNYIKESVNFLNSGLTKTNYLGSSNDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKHLYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVIDTNGFEPTYTASTFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEERFYEGPLTYEKLNHDLYWQITLDAHVGNIMLEKANCIVDSGTSAITVPTDFLNKMLQNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGPGLCMLNIIGLDFPVPTFILGDPFMRKYFTVFDYDNHSVGIALAKKNL
GO Classification
function
endopeptidase activity
pepsin A activity
aspartic-type endopeptidase activity
catalytic activity
hydrolase activity
peptidase activity
process
proteolysis
physiological process
metabolism
macromolecule metabolism
protein metabolism
cellular protein metabolism
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB01218 Halofantrine
DB02505 N-(R-Carboxy-Ethyl)-Alpha-(S)-(2-Phenylethyl)
DB03063 N-(1-Benzyl-3-{[3-(1,3-Dioxo-1,3-Dihydro-Isoindol-2-Yl)-Propionyl]-[2-(Hexahydro-Benzo[1,3]Dioxol-5-Yl)-Ethyl]-Amino}-2-Hydroxy-Propyl)-4-Benzyloxy-3,5-Dimethoxy-Benzamide
DB04373 4-Amino-N-{4-[2-(2,6-Dimethyl-Phenoxy)-Acetylamino]-3-Hydroxy-1-Isobutyl-5-Phenyl-Pentyl}-Benzamide
DB04378 3-Amino-N-{4-[2-(2,6-Dimethyl-Phenoxy)-Acetylamino]-3-Hydroxy-1-Isobutyl-5-Phenyl-Pentyl}-Benzamide

Associated as Prediction

Id Name
DB00041 Aldesleukin
DB00082 Pegvisomant
DB00091 Cyclosporine
DB00136 Calcitriol
DB00153 Ergocalciferol
DB00169 Cholecalciferol
DB00175 Pravastatin
DB00176 Fluvoxamine
DB00180 Flunisolide
DB00182 Amphetamine
DB00184 Nicotine
DB00185 Cevimeline
DB00188 Bortezomib
DB00191 Phentermine
DB00193 Tramadol
DB00195 Betaxolol
DB00196 Fluconazole
DB00197 Troglitazone
DB00199 Erythromycin
DB00201 Caffeine
DB00203 Sildenafil
DB00204 Dofetilide
DB00205 Pyrimethamine
DB00206 Reserpine
DB00207 Azithromycin
DB00208 Ticlopidine
DB00209 Trospium
DB00211 Midodrine
DB00213 Pantoprazole
DB00214 Torasemide
DB00215 Citalopram
DB00216 Eletriptan
DB00220 Nelfinavir
DB00224 Indinavir
DB00227 Lovastatin
DB00231 Temazepam
DB00234 Reboxetine
DB00238 Nevirapine
DB00239 Oxiconazole
DB00240 Alclometasone
DB00243 Ranolazine
DB00245 Benzatropine
DB00246 Ziprasidone
DB00248 Cabergoline
DB00250 Dapsone
DB00252 Phenytoin
DB00254 Doxycycline
DB00255 Diethylstilbestrol
DB00257 Clotrimazole
DB00259 Sulfanilamide
DB00264 Metoprolol
DB00268 Ropinirole
DB00270 Isradipine
DB00273 Topiramate
DB00276 Amsacrine
DB00277 Theophylline
DB00278 Argatroban
DB00280 Disopyramide
DB00281 Lidocaine
DB00283 Clemastine
DB00285 Venlafaxine
DB00286 Conjugated Estrogens
DB00289 Atomoxetine
DB00294 Etonogestrel
DB00295 Morphine
DB00296 Ropivacaine
DB00297 Bupivacaine
DB00301 Flucloxacillin
DB00307 Bexarotene
DB00308 Ibutilide
DB00309 Vindesine
DB00312 Pentobarbital
DB00313 Valproic Acid
DB00316 Acetaminophen
DB00317 Gefitinib
DB00318 Codeine
DB00320 Dihydroergotamine
DB00321 Amitriptyline
DB00324 Fluorometholone
DB00327 Hydromorphone
DB00332 Ipratropium bromide
DB00333 Methadone
DB00334 Olanzapine
DB00336 Nitrofurazone
DB00337 Pimecrolimus
DB00338 Omeprazole
DB00339 Pyrazinamide
DB00342 Terfenadine
DB00343 Diltiazem
DB00344 Protriptyline
DB00346 Alfuzosin
DB00347 Trimethadione
DB00349 Clobazam
DB00353 Methylergonovine
DB00356 Chlorzoxazone
DB00357 Aminoglutethimide
DB00358 Mefloquine
DB00359 Sulfadiazine
DB00361 Vinorelbine
DB00363 Clozapine
DB00365 Grepafloxacin
DB00367 Levonorgestrel
DB00370 Mirtazapine
DB00373 Timolol
DB00377 Palonosetron
DB00379 Mexiletine
DB00381 Amlodipine
DB00390 Digoxin
DB00393 Nimodipine
DB00394 Beclometasone dipropionate
DB00396 Progesterone
DB00398 Sorafenib
DB00400 Griseofulvin
DB00401 Nisoldipine
DB00402 Eszopiclone
DB00404 Alprazolam
DB00409 Remoxipride
DB00412 Rosiglitazone
DB00418 Secobarbital
DB00420 Promazine
DB00421 Spironolactone
DB00422 Methylphenidate
DB00425 Zolpidem
DB00426 Famciclovir
DB00427 Triprolidine
DB00433 Prochlorperazine
DB00435 Nitric Oxide
DB00439 Cerivastatin
DB00440 Trimethoprim
DB00443 Betamethasone
DB00444 Teniposide
DB00446 Chloramphenicol
DB00448 Lansoprazole
DB00451 Levothyroxine
DB00454 Meperidine
DB00455 Loratadine
DB00457 Prazosin
DB00458 Imipramine
DB00468 Quinine
DB00470 Dronabinol
DB00471 Montelukast
DB00472 Fluoxetine
DB00475 Chlordiazepoxide
DB00476 Duloxetine
DB00477 Chlorpromazine
DB00481 Raloxifene
DB00482 Celecoxib
DB00485 Dicloxacillin
DB00489 Sotalol
DB00490 Buspirone
DB00495 Zidovudine
DB00496 Darifenacin
DB00497 Oxycodone
DB00499 Flutamide
DB00501 Cimetidine
DB00502 Haloperidol
DB00503 Ritonavir
DB00514 Dextromethorphan
DB00518 Albendazole
DB00520 Caspofungin
DB00521 Carteolol
DB00528 Lercanidipine
DB00530 Erlotinib
DB00531 Cyclophosphamide
DB00532 Mephenytoin
DB00533 Rofecoxib
DB00537 Ciprofloxacin
DB00539 Toremifene
DB00540 Nortriptyline
DB00541 Vincristine
DB00543 Amoxapine
DB00544 Fluorouracil
DB00545 Pyridostigmine
DB00546 Adinazolam
DB00549 Zafirlukast
DB00553 Methoxsalen
DB00554 Piroxicam
DB00557 Hydroxyzine
DB00559 Bosentan
DB00564 Carbamazepine
DB00567 Cephalexin
DB00568 Cinnarizine
DB00570 Vinblastine
DB00571 Propranolol
DB00574 Fenfluramine
DB00575 Clonidine
DB00580 Valdecoxib
DB00582 Voriconazole
DB00584 Enalapril
DB00586 Diclofenac
DB00588 Fluticasone Propionate
DB00589 Lisuride
DB00590 Doxazosin
DB00592 Piperazine
DB00593 Ethosuximide
DB00598 Labetalol
DB00599 Thiopental
DB00602 Ivermectin
DB00603 Medroxyprogesterone
DB00604 Cisapride
DB00607 Nafcillin
DB00608 Chloroquine
DB00612 Bisoprolol
DB00613 Amodiaquine
DB00615 Rifabutin
DB00617 Paramethadione
DB00619 Imatinib
DB00620 Triamcinolone
DB00622 Nicardipine
DB00623 Fluphenazine
DB00624 Testosterone
DB00625 Efavirenz
DB00627 Niacin
DB00628 Clorazepate
DB00633 Dexmedetomidine
DB00635 Prednisone
DB00636 Clofibrate
DB00637 Astemizole
DB00641 Simvastatin
DB00643 Mebendazole
DB00647 Propoxyphene
DB00655 Estrone
DB00656 Trazodone
DB00661 Verapamil
DB00665 Nilutamide
DB00667 Histamine Phosphate
DB00668 Epinephrine
DB00673 Aprepitant
DB00674 Galantamine
DB00675 Tamoxifen
DB00678 Losartan
DB00679 Thioridazine
DB00682 Warfarin
DB00683 Midazolam
DB00688 Mycophenolate mofetil
DB00690 Flurazepam
DB00694 Daunorubicin
DB00696 Ergotamine
DB00699 Nicergoline
DB00700 Eplerenone
DB00701 Amprenavir
DB00703 Methazolamide
DB00705 Delavirdine
DB00706 Tamsulosin
DB00708 Sufentanil
DB00715 Paroxetine
DB00717 Norethindrone
DB00719 Azatadine
DB00724 Imiquimod
DB00726 Trimipramine
DB00731 Nateglinide
DB00734 Risperidone
DB00736 Esomeprazole
DB00738 Pentamidine
DB00741 Hydrocortisone
DB00744 Zileuton
DB00745 Modafinil
DB00748 Carbinoxamine
DB00751 Epinastine
DB00752 Tranylcypromine
DB00755 Tretinoin
DB00757 Dolasetron
DB00758 Clopidogrel
DB00759 Tetracycline
DB00762 Irinotecan
DB00763 Methimazole
DB00764 Mometasone
DB00768 Olopatadine
DB00769 Hydrocortamate
DB00773 Etoposide
DB00776 Oxcarbazepine
DB00778 Roxithromycin
DB00780 Phenelzine
DB00783 Estradiol
DB00784 Mefenamic acid
DB00788 Naproxen
DB00792 Tripelennamine
DB00794 Primidone
DB00795 Sulfasalazine
DB00796 Candesartan
DB00799 Tazarotene
DB00802 Alfentanil
DB00805 Minaprine
DB00808 Indapamide
DB00810 Biperiden
DB00812 Phenylbutazone
DB00813 Fentanyl
DB00814 Meloxicam
DB00818 Propofol
DB00819 Acetazolamide
DB00820 Tadalafil
DB00822 Disulfiram
DB00829 Diazepam
DB00834 Mifepristone
DB00835 Brompheniramine
DB00836 Loperamide
DB00842 Oxazepam
DB00843 Donepezil
DB00845 Clofazimine
DB00850 Perphenazine
DB00852 Pseudoephedrine
DB00853 Temozolomide
DB00856 Chlorphenesin
DB00857 Terbinafine
DB00860 Prednisolone
DB00862 Vardenafil
DB00863 Ranitidine
DB00864 Tacrolimus
DB00865 Benzphetamine
DB00866 Alprenolol
DB00869 Dorzolamide
DB00872 Conivaptan
DB00877 Sirolimus
DB00882 Clomifene
DB00883 Isosorbide Dinitrate
DB00889 Granisetron
DB00897 Triazolam
DB00898 Ethanol
DB00904 Ondansetron
DB00906 Tiagabine
DB00907 Cocaine
DB00908 Quinidine
DB00909 Zonisamide
DB00910 Paricalcitol
DB00911 Tinidazole
DB00912 Repaglinide
DB00914 Phenformin
DB00916 Metronidazole
DB00918 Almotriptan
DB00921 Buprenorphine
DB00924 Cyclobenzaprine
DB00925 Phenoxybenzamine
DB00932 Tipranavir
DB00933 Mesoridazine
DB00934 Maprotiline
DB00938 Salmeterol
DB00943 Zalcitabine
DB00945 Acetylsalicylic acid
DB00946 Phenprocoumon
DB00947 Fulvestrant
DB00949 Felbamate
DB00950 Fexofenadine
DB00951 Isoniazid
DB00956 Hydrocodone
DB00959 Methylprednisolone
DB00960 Pindolol
DB00962 Zaleplon
DB00967 Desloratadine
DB00969 Alosetron
DB00972 Azelastine
DB00973 Ezetimibe
DB00976 Telithromycin
DB00977 Ethinyl Estradiol
DB00980 Ramelteon
DB00983 Formoterol
DB00987 Cytarabine
DB00988 Dopamine
DB00989 Rivastigmine
DB00990 Exemestane
DB00997 Doxorubicin
DB01001 Salbutamol
DB01002 Levobupivacaine
DB01005 Hydroxyurea
DB01006 Letrozole
DB01007 Tioconazole
DB01008 Busulfan
DB01009 Ketoprofen
DB01011 Metyrapone
DB01012 Cinacalcet
DB01015 Sulfamethoxazole
DB01016 Glyburide
DB01018 Guanfacine
DB01020 Isosorbide Mononitrate
DB01023 Felodipine
DB01026 Ketoconazole
DB01028 Methoxyflurane
DB01029 Irbesartan
DB01030 Topotecan
DB01032 Probenecid
DB01035 Procainamide
DB01036 Tolterodine
DB01037 Selegiline
DB01039 Fenofibrate
DB01041 Thalidomide
DB01045 Rifampin
DB01049 Ergoloid mesylate
DB01050 Ibuprofen
DB01054 Nitrendipine
DB01058 Praziquantel
DB01059 Norfloxacin
DB01062 Oxybutynin
DB01067 Glipizide
DB01068 Clonazepam
DB01069 Promethazine
DB01071 Mequitazine
DB01072 Atazanavir
DB01074 Perhexiline
DB01075 Diphenhydramine
DB01076 Atorvastatin
DB01079 Tegaserod
DB01083 Orlistat
DB01085 Pilocarpine
DB01087 Primaquine
DB01093 Dimethyl sulfoxide
DB01095 Fluvastatin
DB01096 Oxamniquine
DB01098 Rosuvastatin
DB01100 Pimozide
DB01103 Quinacrine
DB01104 Sertraline
DB01105 Sibutramine
DB01107 Methyprylon
DB01110 Miconazole
DB01114 Chlorpheniramine
DB01115 Nifedipine
DB01118 Amiodarone
DB01124 Tolbutamide
DB01126 Dutasteride
DB01127 Econazole
DB01128 Bicalutamide
DB01129 Rabeprazole
DB01131 Proguanil
DB01132 Pioglitazone
DB01136 Carvedilol
DB01137 Levofloxacin
DB01138 Sulfinpyrazone
DB01142 Doxepin
DB01149 Nefazodone
DB01151 Desipramine
DB01156 Bupropion
DB01159 Halothane
DB01162 Terazosin
DB01166 Cilostazol
DB01167 Itraconazole
DB01169 Arsenic trioxide
DB01170 Guanethidine
DB01171 Moclobemide
DB01173 Orphenadrine
DB01174 Phenobarbital
DB01175 Escitalopram
DB01177 Idarubicin
DB01179 Podofilox
DB01181 Ifosfamide
DB01182 Propafenone
DB01183 Naloxone
DB01184 Domperidone
DB01186 Pergolide
DB01190 Clindamycin
DB01191 Dexfenfluramine
DB01192 Oxymorphone
DB01193 Acebutolol
DB01194 Brinzolamide
DB01195 Flecainide
DB01196 Estramustine
DB01197 Captopril
DB01198 Zopiclone
DB01200 Bromocriptine
DB01201 Rifapentine
DB01204 Mitoxantrone
DB01206 Lomustine
DB01211 Clarithromycin
DB01215 Estazolam
DB01216 Finasteride
DB01217 Anastrozole
DB01218 Halofantrine
DB01219 Dantrolene
DB01220 Rifaximin
DB01221 Ketamine
DB01222 Budesonide
DB01223 Aminophylline
DB01224 Quetiapine
DB01227 Levomethadyl Acetate
DB01228 Encainide
DB01229 Paclitaxel
DB01232 Saquinavir
DB01233 Metoclopramide
DB01234 Dexamethasone
DB01235 Levodopa
DB01236 Sevoflurane
DB01238 Aripiprazole
DB01241 Gemfibrozil
DB01242 Clomipramine
DB01244 Bepridil
DB01246 Trimeprazine
DB01248 Docetaxel
DB01253 Ergonovine
DB01254 Dasatinib
DB01256 Retapamulin
DB01258 Aliskiren
DB01259 Lapatinib
DB01261 Sitagliptin
DB01263 Posaconazole
DB01264 Darunavir
DB01267 Paliperidone
DB01268 Sunitinib
DB01274 Arformoterol
DB01275 Hydralazine
DB01301 Rolitetracycline
DB01319 Fosamprenavir
DB01320 Fosphenytoin
DB01321 Josamycin
DB01333 Cefradine
DB01349 Tasosartan
DB01355 Hexobarbital
DB01361 Troleandomycin
DB01369 Quinupristin
DB01380 Cortisone acetate
DB01384 Paramethasone
DB01388 Mibefradil
DB01392 Yohimbine
DB01393 Bezafibrate
DB01394 Colchicine
DB01396 Digitoxin
DB01403 Methotrimeprazine
DB01406 Danazol
DB01409 Tiotropium
DB01410 Ciclesonide
DB01411 Pranlukast
DB01418 Acenocoumarol
DB01424 Aminophenazone
DB01426 Ajmaline
DB01429 Aprindine
DB01431 Allylestrenol
DB01435 Antipyrine
DB01437 Glutethimide
DB01466 Ethylmorphine
DB01472 4-Methoxyamphetamine
DB01544 Flunitrazepam
DB01551 Dihydrocodeine
DB01558 Bromazepam
DB01559 Clotiazepam
DB01562 1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine
DB01576 Dextroamphetamine
DB01577 Methamphetamine
DB01580 Oxprenolol
DB01583 Liotrix
DB01587 Ketazolam
DB01588 Prazepam
DB01589 Quazepam
DB01590 Everolimus
DB01591 Solifenacin
DB01595 Nitrazepam
DB01601 Lopinavir
DB01609 Deferasirox
DB01611 Hydroxychloroquine
DB01621 Pipotiazine
DB01623 Thiothixene
DB01624 Zuclopenthixol
DB01628 Etoricoxib
DB01698 Rutin
DB01708 Dehydroepiandrosterone
DB01764 Dalfopristin
DB02505 N-(R-Carboxy-Ethyl)-Alpha-(S)-(2-Phenylethyl)
DB02701 Nicotinamide
DB02709 Resveratrol
DB03014 Heme
DB03063 N-(1-Benzyl-3-{[3-(1,3-Dioxo-1,3-Dihydro-Isoindol-2-Yl)-Propionyl]-[2-(Hexahydro-Benzo[1,3]Dioxol-5-Yl)-Ethyl]-Amino}-2-Hydroxy-Propyl)-4-Benzyloxy-3,5-Dimethoxy-Benzamide
DB03128 Acetylcholine
DB03701 Vanoxerine
DB03783 Phenacetin
DB03796 Palmitic Acid
DB04216 Quercetin
DB04373 4-Amino-N-{4-[2-(2,6-Dimethyl-Phenoxy)-Acetylamino]-3-Hydroxy-1-Isobutyl-5-Phenyl-Pentyl}-Benzamide
DB04378 3-Amino-N-{4-[2-(2,6-Dimethyl-Phenoxy)-Acetylamino]-3-Hydroxy-1-Isobutyl-5-Phenyl-Pentyl}-Benzamide
DB04572 Thiotepa
DB04574 Estropipate
DB04794 Bifonazole
DB04817 Dipyrone
DB04828 Zomepirac
DB04833 Methaqualone
DB04835 Maraviroc
DB04840 Debrisoquin
DB04841 Flunarizine
DB04844 Tetrabenazine
DB04845 Ixabepilone
DB04855 Dronedarone
DB04861 Nebivolol
DB04868 Nilotinib
DB04871 Lorcaserin
DB04920 Clevidipine
DB04930 Permethrin
DB04938 Ospemifene
DB04946 Iloperidone
DB05039 Indacaterol
DB05109 Trabectedin
DB05271 Rotigotine
DB05294 Vandetanib
DB05521 Telaprevir
DB05773 ado-trastuzumab emtansine
DB05812 Abiraterone
DB06144 Sertindole
DB06148 Mianserin
DB06155 Rimonabant
DB06201 Rufinamide
DB06203 Alogliptin
DB06204 Tapentadol
DB06207 Silodosin
DB06209 Prasugrel
DB06210 Eltrombopag
DB06212 Tolvaptan
DB06216 Asenapine
DB06228 Rivaroxaban
DB06237 Avanafil
DB06267 Udenafil
DB06268 Sitaxentan
DB06287 Temsirolimus
DB06335 Saxagliptin
DB06589 Pazopanib
DB06605 Apixaban
DB06616 Bosutinib
DB06626 Axitinib
DB06684 Vilazodone
DB06691 Mepyramine
DB06697 Artemether
DB06700 Desvenlafaxine
DB06701 Dexmethylphenidate
DB06702 Fesoterodine
DB06708 Lumefantrine
DB06710 Methyltestosterone
DB06712 Nilvadipine
DB06726 Bufuralol
DB06727 Sparteine
DB06729 Sulfaphenazole
DB06730 Gestodene
DB06731 Seproxetine
DB06770 Benzyl alcohol
DB06772 Cabazitaxel
DB06777 Chenodeoxycholic acid
DB06800 Methylnaltrexone
DB08607 (5R)-5-(4-{[(2R)-6-HYDROXY-2,5,7,8-TETRAMETHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL]METHOXY}BENZYL)-1,3-THIAZOLIDINE-2,4-DIONE
DB08811 Tofisopam
DB08815 Lurasidone
DB08816 Ticagrelor
DB08820 Ivacaftor
DB08827 Lomitapide
DB08828 Vismodegib
DB08860 Pitavastatin
DB08864 Rilpivirine
DB08866 Estradiol valerate/Dienogest
DB08868 Fingolimod
DB08870 BRENTUXIMAB VEDOTIN
DB08873 Boceprevir
DB08875 Cabozantinib
DB08877 Ruxolitinib
DB08881 Vemurafenib
DB08882 Linagliptin
DB08883 Perampanel
DB08893 Mirabegron
DB08896 Regorafenib
DB08899 Enzalutamide
DB08901 Ponatinib
DB08903 Bedaquiline
DB08906 Fluticasone furoate
DB08907 Canagliflozin
DB08910 Pomalidomide
DB08911 Trametinib
DB08912 Dabrafenib
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