DT-Web

DB04817 - Dipyrone


Identification
Name Dipyrone
Accession Number DB04817
Type small molecule
Description Dipyrone, formerly marketed as Dimethone tablets and injection, Protemp oral liquid, and other drug products, was associated with potentially fatal agranulocytosis. Approvals of the NDA's for dipyrone drug products were withdrawn on June 27, 1977 (see the Federal Register of June 17, 1977 (42 FR 30893)). Withdrawn from the Canadian market in 1963.
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 333.339
Groups withdrawn
Monoisotopic Weight 333.07592138
Pharmacology
Indication Used in the past as a powerful painkiller and fever reducer.
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Prostaglandin G/H synthase 1
Name Prostaglandin G/H synthase 1
Gene Name PTGS1
Pharmacological action unknown
Actions Not Available
References
  • Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. - Pubmed
DTHybrid score 0.3955

Enzymes


Cytochrome P450 2B6
Name Cytochrome P450 2B6
Gene Name CYP2B6
Actions inducer
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.2054
Cytochrome P450 3A4
Name Cytochrome P450 3A4
Gene Name CYP3A4
Actions inducer
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.3365

Predictions


Id Partner name Gene Name Score
4757 Cytochrome P450 2C9 CYP2C9 0.152
290 Prostaglandin G/H synthase 2 PTGS2 0.145
4119 Cytochrome P450 2D6 CYP2D6 0.1165
6016 Cytochrome P450 2C19 CYP2C19 0.1126
4200 Cytochrome P450 1A2 CYP1A2 0.1034
4924 Cytochrome P450 2C8 CYP2C8 0.1002
1588 Multidrug resistance protein 1 ABCB1 0.0907
4118 Cytochrome P450 3A5 CYP3A5 0.0818
6013 Cytochrome P450 2E1 CYP2E1 0.0636
6107 Cytochrome P450 3A7 CYP3A7 0.0566
587 Serum albumin ALB 0.0519
5718 Cytochrome P450 2A6 CYP2A6 0.0478
6024 Cytochrome P450 1A1 CYP1A1 0.0398
1729 Solute carrier family 22 member 6 SLC22A6 0.0358
275 Arachidonate 5-lipoxygenase ALOX5 0.0274
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.027
6106 Cytochrome P450 2C18 CYP2C18 0.0268
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0263
492 Histamine H1 receptor HRH1 0.0246
3811 Cytochrome P450 19A1 CYP19A1 0.0229
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0218
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0217
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0215
824 Sodium-dependent serotonin transporter SLC6A4 0.0193
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0192
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0187
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0186
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0176
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0173
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0172
862 Multidrug resistance-associated protein 1 ABCC1 0.0172
6142 Solute carrier family 22 member 8 SLC22A8 0.0171
871 Glucocorticoid receptor NR3C1 0.0168
238 Peroxisome proliferator-activated receptor gamma PPARG 0.016
556 Alpha-1A adrenergic receptor ADRA1A 0.0156
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.015
136 Estrogen receptor ESR1 0.015
3923 Cholinesterase BCHE 0.0149
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0148
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0147
847 Mu-type opioid receptor OPRM1 0.0146
2164 Multidrug resistance-associated protein 4 ABCC4 0.0141
502 5-hydroxytryptamine 2A receptor HTR2A 0.0141
731 HIV-1 protease HIV-1 protease 0.0138
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0134
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0133
831 D(2) dopamine receptor DRD2 0.0133
260 Cytochrome P450 51 ERG11 0.0132
761 Cytochrome P450 51 ERG11 0.0132
3163 Cytochrome P450 51 cyp51 0.0132
1757 Myeloperoxidase MPO 0.0131
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0123
713 Sodium-dependent dopamine transporter SLC6A3 0.0119
318 Alpha-2A adrenergic receptor ADRA2A 0.0119
467 Delta-type opioid receptor OPRD1 0.0119
6145 Solute carrier family 22 member 1 SLC22A1 0.0118
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0117
1898 Cytochrome P450 1B1 CYP1B1 0.0115
1507 Cytochrome c CYCS 0.0111
6144 Solute carrier family 22 member 2 SLC22A2 0.011
696 Kappa-type opioid receptor OPRK1 0.0107
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0102
1024 Solute carrier family 22 member 11 SLC22A11 0.0099
468 Cytochrome P450 4A11 CYP4A11 0.0099
776 Bile salt export pump ABCB11 0.0097
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0096
122 P2Y purinoceptor 12 P2RY12 0.0095
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0095
320 5-hydroxytryptamine 1A receptor HTR1A 0.0094
811 Translocator protein TSPO 0.0094
118 Organic cation/carnitine transporter 2 SLC22A5 0.0094
373 Transthyretin TTR 0.0092
6143 Solute carrier family 22 member 7 SLC22A7 0.0092
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0092
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0092
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0091
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0091
818 50S ribosomal protein L10 rplJ 0.009
274 Muscarinic acetylcholine receptor M5 CHRM5 0.009
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0089
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0088
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0088
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0088
465 Calmodulin CALM1 0.0087
590 5-hydroxytryptamine 2C receptor HTR2C 0.0087
3312 Fatty acid-binding protein, brain FABP7 0.0086
146 Androgen receptor AR 0.0084
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0083
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0082
185 Vasopressin V1a receptor AVPR1A 0.0082
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.008
232 Corticosteroid-binding globulin SERPINA6 0.008
322 Vasopressin V2 receptor AVPR2 0.008
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0079
6068 Guanylate cyclase soluble subunit alpha-2 GUCY1A2 0.0079
341 5-hydroxytryptamine 3 receptor HTR3A 0.0076
632 Alpha-1B adrenergic receptor ADRA1B 0.0076
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0074
174 Sigma 1-type opioid receptor SIGMAR1 0.0074
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0073
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.0072
70 Type-1 angiotensin II receptor AGTR1 0.0071
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0069
4120 NADPH--cytochrome P450 reductase POR 0.0068
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0068
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0068
789 Alpha-1D adrenergic receptor ADRA1D 0.0067
23 D(1A) dopamine receptor DRD1 0.0066
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0066
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0066
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0066
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0066
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0064
705 Glutamate receptor 1 GRIA1 0.0064
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.0064
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0063
482 Glycine receptor subunit alpha-1 GLRA1 0.0063
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.0062
6147 Solute carrier family 22 member 3 SLC22A3 0.0062
6102 Arylamine N-acetyltransferase 2 NAT2 0.0062
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0062
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0062
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.0062
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.0062
614 Progesterone receptor PGR 0.0062
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0062
427 Substance-P receptor TACR1 0.0062
6043 Putative G-protein coupled receptor 44 GPR44 0.0062
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0061
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0061
6137 Multidrug resistance-associated protein 6 ABCC6 0.006
766 Beta-2 adrenergic receptor ADRB2 0.0059
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.0059
4148 Serine/threonine-protein kinase mTOR MTOR 0.0059
504 Mast/stem cell growth factor receptor KIT 0.0059
68 Cannabinoid receptor 1 CNR1 0.0059
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.0059
6031 Cytochrome P450 3A43 CYP3A43 0.0059
738 Monocarboxylate transporter 1 SLC16A1 0.0059
4604 Liver carboxylesterase 1 CES1 0.0058
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0057
7 Nitric oxide synthase, inducible NOS2 0.0057
6085 Fatty acid-binding protein, intestinal FABP2 0.0057
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0057
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0057
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0056
703 NADPH azoreductase azr 0.0056
891 Dihydropteroate synthase folP 0.0056
5359 Dihydropteroate synthase folP 0.0056
7175 Dihydropteroate synthase sulI 0.0056
241 Calcium-transporting ATPase type 2C member 1 ATP2C1 0.0056
716 5-hydroxytryptamine 7 receptor HTR7 0.0056
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0055
1656 CYP2B protein CYP2B 0.0055
6220 Aryl hydrocarbon receptor AHR 0.0055
29 Tubulin beta-1 chain TUBB1 0.0055
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0054
833 Organic cation/carnitine transporter 1 SLC22A4 0.0054
606 Cytochrome P450 27, mitochondrial CYP27A1 0.0054
6014 Cytochrome P450 2A13 CYP2A13 0.0053
537 ATP synthase delta chain, mitochondrial ATP5D 0.0053
6020 Aldehyde oxidase AOX1 0.0053
850 Vasopressin V1b receptor AVPR1B 0.0053
885 5-hydroxytryptamine 1B receptor HTR1B 0.0053
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0053
638 D(3) dopamine receptor DRD3 0.0053
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0052
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0052
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0052
756 Sex hormone-binding globulin SHBG 0.0052
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0052
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0052
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0051
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0051
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0051
725 5-hydroxytryptamine 1D receptor HTR1D 0.005
723 Cytosolic phospholipase A2 PLA2G4A 0.005
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.005
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.005
80 Peroxisome proliferator-activated receptor alpha PPARA 0.005
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.005
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.005
817 DNA topoisomerase 2-alpha TOP2A 0.005
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.005
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0049
6182 Cytochrome P450 2J2 CYP2J2 0.0049
3941 Amine oxidase [flavin-containing] A MAOA 0.0048
161 Tubulin beta chain TUBB 0.0048
312 Tubulin beta chain TUB2 0.0048
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0048
952 Dipeptidyl peptidase 4 DPP4 0.0047
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0047
856 Vitamin D3 receptor VDR 0.0046
869 Estrogen receptor beta ESR2 0.0046
629 Alpha-2B adrenergic receptor ADRA2B 0.0045
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0045
193 Beta-1 adrenergic receptor ADRB1 0.0045
6012 Tryptophan 2,3-dioxygenase TDO2 0.0045
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0045
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0045
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0045
1648 Elastin ELN 0.0044
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0044
3947 Xanthine dehydrogenase/oxidase XDH 0.0043
6148 Multidrug resistance-associated protein 7 ABCC10 0.0042
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0042
378 Alpha-2C adrenergic receptor ADRA2C 0.0042
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0042
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0042
777 Tumor necrosis factor TNF 0.0042
3997 Cytochrome P450 24A1, mitochondrial CYP24A1 0.0041
6136 Multidrug resistance-associated protein 5 ABCC5 0.004
921 Glutamate receptor 2 GRIA2 0.004
1010 Cytochrome P450 51A1 CYP51A1 0.0039
4132 Chloride channel protein ClC-Ka CLCNKA 0.0039
276 Sodium- and chloride-dependent GABA transporter 1 SLC6A1 0.0039
3939 Amine oxidase [flavin-containing] B MAOB 0.0039
1129 C-C chemokine receptor type 5 CCR5 0.0039
1629 Transcription factor AP-1 JUN 0.0039
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0039
3932 Glutathione S-transferase A2 GSTA2 0.0039
228 Beta platelet-derived growth factor receptor PDGFRB 0.0038
436 5-hydroxytryptamine 2B receptor HTR2B 0.0038
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0038
5878 Alpha-7 nicotinic cholinergic receptor subunit CHRFAM7A 0.0038
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.0038
2853 14 kDa fatty acid-binding protein Not Available 0.0037
407 Vascular endothelial growth factor receptor 2 KDR 0.0037
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0035
6103 Arylamine N-acetyltransferase 1 NAT1 0.0035
130 Prostacyclin synthase PTGIS 0.0035
284 DNA-directed RNA polymerase beta chain rpoB 0.0035
5773 DNA-directed RNA polymerase beta chain rpoB 0.0035
4237 50S ribosomal protein L22 rplV 0.0035
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0035
939 50S ribosomal protein L3 rplC 0.0035
6138 Multidrug resistance protein 3 ABCB4 0.0034
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0034
558 Solute carrier family 12 member 1 SLC12A1 0.0034
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0034
26 Vascular endothelial growth factor receptor 3 FLT4 0.0033
844 Epidermal growth factor receptor EGFR 0.0033
474 Acetylcholinesterase ACHE 0.0033
596 3-oxo-5-alpha-steroid 4-dehydrogenase 1 SRD5A1 0.0033
823 Fibroblast growth factor receptor 2 FGFR2 0.0033
295 Carbonic anhydrase 1 CA1 0.0033
814 Ryanodine receptor 1 RYR1 0.0033
124 Histamine H2 receptor HRH2 0.0032
4784 Beta-mannosidase manB 0.0032
6695 Beta-mannosidase BT_0458 0.0032
32 Vascular endothelial growth factor receptor 1 FLT1 0.0032
592 Carbonic anhydrase 4 CA4 0.0032
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0032
140 30S ribosomal protein S9 rpsI 0.0031
6719 30S ribosomal protein S9 rpsI 0.0031
6725 30S ribosomal protein S9 rpsI 0.0031
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0031
432 D(4) dopamine receptor DRD4 0.0031
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0031
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0031
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0031
106 Cannabinoid receptor 2 CNR2 0.003
2578 Tubulin beta-3 chain TUBB3 0.003
2285 Streptogramin A acetyltransferase vatD 0.003
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.003
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.003
1618 High affinity nerve growth factor receptor NTRK1 0.003
581 Cytochrome P450 2R1 CYP2R1 0.003
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0029
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0029
2998 Sialic acid-binding Ig-like lectin 7 SIGLEC7 0.0028
131 Synaptic vesicular amine transporter SLC18A2 0.0028
1050 Bile salt sulfotransferase SULT2A1 0.0028
102 DNA topoisomerase I, mitochondrial TOP1MT 0.0028
6131 Carbonic anhydrase 14 CA14 0.0027
634 Squalene monooxygenase SQLE 0.0027
7196 Squalene monooxygenase ERG1 0.0027
4173 Tyrosine-protein kinase JAK2 JAK2 0.0027
459 Retinoic acid receptor RXR-alpha RXRA 0.0027
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0027
6500 Phospholipase A2 PLA2G1B 0.0026
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0026
1714 Mitogen-activated protein kinase 3 MAPK3 0.0026
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0026
2183 Fatty acid-binding protein, adipocyte FABP4 0.0026
904 Glutathione S-transferase P GSTP1 0.0026
49 Endothelin B receptor EDNRB 0.0026
78 Acetyl-CoA acetyltransferase, mitochondrial ACAT1 0.0025
6146 High affinity copper uptake protein 1 SLC31A1 0.0025
528 5-hydroxytryptamine 1E receptor HTR1E 0.0025
6141 Sodium/bile acid cotransporter SLC10A1 0.0025
2207 Rhodopsin RHO 0.0025
4787 Envelope glycoprotein gp160 env 0.0025
4820 Envelope glycoprotein gp160 env 0.0025
5727 Envelope glycoprotein gp160 env 0.0025
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.0025
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.0025
489 Monocarboxylate transporter 2 SLC16A7 0.0025
563 Thyroid peroxidase TPO 0.0025
768 FK506-binding protein 1A FKBP1A 0.0025
1192 Sulfotransferase 1A1 SULT1A1 0.0024
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0024
578 Endothelin-1 receptor EDNRA 0.0024
759 Free fatty acid receptor 1 FFAR1 0.0024
1818 Long-chain-fatty-acid--CoA ligase 3 ACSL3 0.0024
544 Potassium voltage-gated channel subfamily E member 1 KCNE1 0.0024
357 Carbonic anhydrase 2 CA2 0.0024
6033 High affinity interleukin-8 receptor A CXCR1 0.0024
1483 Membrane copper amine oxidase AOC3 0.0024
6039 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A PDE11A 0.0024
2297 Genome polyprotein Not Available 0.0024
2322 Genome polyprotein Not Available 0.0024
2694 Genome polyprotein Not Available 0.0024
2719 Genome polyprotein Not Available 0.0024
2860 Genome polyprotein Not Available 0.0024
2928 Genome polyprotein Not Available 0.0024
3160 Genome polyprotein Not Available 0.0024
3260 Genome polyprotein Not Available 0.0024
4783 Genome polyprotein Not Available 0.0024
5726 Genome polyprotein Not Available 0.0024
5779 Genome polyprotein Not Available 0.0024
5867 Genome polyprotein Not Available 0.0024
6253 Genome polyprotein Not Available 0.0024
6301 Genome polyprotein Not Available 0.0024
6380 Genome polyprotein Not Available 0.0024
6381 Genome polyprotein Not Available 0.0024
6437 Genome polyprotein Not Available 0.0024
6520 Genome polyprotein Not Available 0.0024
6521 Genome polyprotein Not Available 0.0024
6652 Genome polyprotein Not Available 0.0024
6734 Genome polyprotein Not Available 0.0024
6735 Genome polyprotein Not Available 0.0024
6736 Genome polyprotein Not Available 0.0024
6737 Genome polyprotein Not Available 0.0024
6738 Genome polyprotein Not Available 0.0024
6739 Genome polyprotein Not Available 0.0024
6744 Genome polyprotein Not Available 0.0024
6748 Genome polyprotein Not Available 0.0024
6894 Genome polyprotein Not Available 0.0024
6898 Genome polyprotein Not Available 0.0024
5852 Type-2 angiotensin II receptor AGTR2 0.0024
3601 Dihydropteroate synthase 1 folP1 0.0024
3807 Dihydropteroate synthase 1 folP1 0.0024
3808 Dihydropteroate synthase 2 folP2 0.0024
642 3-oxo-5-alpha-steroid 4-dehydrogenase 2 SRD5A2 0.0023
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0023
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0023
1353 DNA topoisomerase 1 TOP1 0.0023
3552 DNA topoisomerase 1 topA 0.0023
2236 Casein kinase II subunit alpha CSNK2A1 0.0023
1262 Corticotropin-lipotropin POMC 0.0023
84 Nuclear receptor 0B1 NR0B1 0.0022
737 Mineralocorticoid receptor NR3C2 0.0022
990 Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 0.0022
6149 Solute carrier family 22 member 10 SLC22A10 0.0022
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0022
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0022
3480 Mannan endo-1,4-beta-mannosidase manA 0.0022
259 Microsomal triglyceride transfer protein large subunit MTTP 0.0022
2449 Tubulin alpha-3 chain TUBA1A 0.0021
298 Renin REN 0.0021
6506 Stathmin-4 STMN4 0.0021
1039 Histone deacetylase 9 HDAC9 0.0021
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.0021
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.0021
3437 Eosinophil lysophospholipase CLC 0.0021
1053 BC269730_2 FADS1 0.0021
1395 Sodium/calcium exchanger 1 SLC8A1 0.0021
380 Cytochrome P450 17A1 CYP17A1 0.0021
163 D(1B) dopamine receptor DRD5 0.0021
741 Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 0.0021
2539 Tubulin alpha-1 chain TUBA4A 0.0021
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0021
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0021
183 Vascular endothelial growth factor A VEGFA 0.0021
33 Cystine/glutamate transporter SLC7A11 0.002
94 5-hydroxytryptamine 4 receptor HTR4 0.002
780 Retinoic acid receptor RXR-gamma RXRG 0.002
2981 Phospholipase A2, membrane associated PLA2G2A 0.002
4103 Proteasome subunit beta type 2 PSMB2 0.002
4102 Proteasome subunit beta type 5 PSMB5 0.002
4101 Proteasome subunit beta type 1 PSMB1 0.002
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.002
6432 Transporter snf 0.002
750 Voltage-dependent calcium channel gamma-1 subunit CACNG1 0.002
1558 Transient receptor potential cation channel subfamily V member 1 TRPV1 0.002
4199 Sphingosine 1-phosphate receptor Edg-8 S1PR5 0.002
908 Glutathione S-transferase theta-1 GSTT1 0.002
1650 Heme carrier protein 1 SLC46A1 0.0019
633 Penicillin-binding proteins 1A/1B pbpA 0.0019
1374 Natriuretic peptides B NPPB 0.0019
1827 Gap junction alpha-1 protein GJA1 0.0019
1908 Vascular cell adhesion protein 1 VCAM1 0.0019
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0019
2499 Tubulin beta-2C chain TUBB2C 0.0019
233 Potassium channel subfamily K member 2 KCNK2 0.0019
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0019
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.0019
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0019
88 Retinoic acid receptor RXR-beta RXRB 0.0019
5787 Angiopoietin-1 receptor TEK 0.0019
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0019
477 DNA topoisomerase 4 subunit A parC 0.0019
886 DNA topoisomerase 4 subunit A parC 0.0019
6226 DNA topoisomerase 4 subunit A parC 0.0019
1992 Vitamin D-binding protein GC 0.0019
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0018
404 DNA gyrase subunit A gyrA 0.0018
6224 DNA gyrase subunit A gyrA 0.0018
511 5-hydroxytryptamine 1F receptor HTR1F 0.0018
5998 Toll-like receptor 8 TLR8 0.0018
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0018
319 Opioid receptor, sigma 1 OPRS1 0.0018
4238 50S ribosomal protein L4 rplD 0.0018
5578 50S ribosomal protein L4 rplD 0.0018
6173 50S ribosomal protein L4 rplD 0.0018
6219 50S ribosomal protein L4 rplD 0.0018
712 Tubulin alpha chain TUB1 0.0018
1968 ATP-sensitive inward rectifier potassium channel 12 KCNJ12 0.0018
565 Extracellular calcium-sensing receptor CASR 0.0018
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0018
683 Potassium transporter GK0582 0.0018
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0018
67 Prolyl 4-hydroxylase subunit alpha-1 P4HA1 0.0017
613 Atrial natriuretic peptide receptor A NPR1 0.0017
621 Periplasmic [Fe] hydrogenase 1 Not Available 0.0017
543 Penicillin-binding protein 1B mrcB 0.0017
6186 Penicillin-binding protein 1B ponB 0.0017
6822 Penicillin-binding protein 1b pbp1b 0.0017
6844 Penicillin-binding protein 1b pbp1b 0.0017
1630 Integrin beta-2 ITGB2 0.0017
1256 5-hydroxytryptamine 6 receptor HTR6 0.0017
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0017
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0017
159 Penicillin-binding protein 2B penA 0.0017
6121 Penicillin-binding protein 2B penA 0.0017
165 FL cytokine receptor FLT3 0.0017
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0017
4192 DNA topoisomerase 2-beta TOP2B 0.0017
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0016
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0016
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0016
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0016
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0016
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0016
1852 Microtubule-associated protein 2 MAP2 0.0016
173 Toll-like receptor 7 TLR7 0.0016
822 Aldose reductase AKR1B1 0.0016
3233 Bile acid receptor NR1H4 0.0015
251 Alcohol dehydrogenase 1A ADH1A 0.0015
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0015
4785 Ig gamma-1 chain C region IGHG1 0.0015
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.0015
3937 Fatty-acid amide hydrolase FAAH 0.0015
273 Apoptosis regulator Bcl-2 BCL2 0.0015
719 Retinoic acid receptor responder protein 1 RARRES1 0.0014
770 Retinoic acid-induced protein 3 GPRC5A 0.0014
1864 RET proto-oncogene RET 0.0014
1541 Metalloproteinase mmp20 0.0014
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0014
820 Glycine receptor subunit alpha-2 GLRA2 0.0014
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0014
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0014
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0014
1275 Estrogen sulfotransferase SULT1E1 0.0014
291 Nitric-oxide synthase, endothelial NOS3 0.0014
6032 PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) fas 0.0014
444 Alcohol dehydrogenase 1B ADH1B 0.0014
469 Annexin A1 ANXA1 0.0014
896 Glutathione S-transferase Mu 1 GSTM1 0.0014
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0014
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0014
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0014
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0014
605 Fumarate reductase flavoprotein subunit frdA 0.0014
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0014
3673 Fumarate reductase flavoprotein subunit fccA 0.0014
4912 Fumarate reductase flavoprotein subunit ifcA 0.0014
6549 Fumarate reductase flavoprotein subunit frdA 0.0014
936 Ephrin type-A receptor 2 EPHA2 0.0013
3809 Estrogen-related receptor gamma ESRRG 0.0013
5798 Mitogen-activated protein kinase 11 MAPK11 0.0013
4122 Histone deacetylase 2 HDAC2 0.0013
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.0013
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.0013
569 Retinal dehydrogenase 2 ALDH1A2 0.0013
267 Plasminogen activator inhibitor 1 SERPINE1 0.0013
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0013
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0013
6116 Gastric triacylglycerol lipase LIPF 0.0012
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.0012
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0012
2021 Thrombomodulin THBD 0.0012
16 Adenosine A1 receptor ADORA1 0.0012
3806 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A 0.0012
3823 Cytokine receptor common gamma chain IL2RG 0.0012
85 Growth hormone receptor GHR 0.0012
6126 Carbonic anhydrase 7 CA7 0.0012
2107 Microtubule-associated protein 1A MAP1A 0.0012
571 Melatonin receptor type 1A MTNR1A 0.0012
362 Melatonin receptor type 1B MTNR1B 0.0012
338 DNA polymerase UL30 0.0012
379 DNA polymerase UL54 0.0012
697 DNA polymerase ORF28 0.0012
2482 DNA polymerase 43 0.0012
4104 DNA polymerase BALF5 0.0012
611 Retinal dehydrogenase 1 ALDH1A1 0.0012
517 Alcohol dehydrogenase 1C ADH1C 0.0012
1768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit GNG2 0.0012
1295 Fatty acid synthase FASN 0.0012
1571 G protein-activated inward rectifier potassium channel 1 KCNJ3 0.0012
1268 Neuropeptide S receptor NPSR1 0.0012
1581 G protein-activated inward rectifier potassium channel 2 KCNJ6 0.0012
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0012
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0012
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0012
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0012
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0012
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0012
76 Nitric-oxide synthase, brain NOS1 0.0012
6221 Steroid hormone receptor ERR1 ESRRA 0.0012
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0012
1178 Adenosine A2a receptor ADORA2A 0.0011
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0011
239 Coagulation factor X F10 0.0011
5934 Cytochrome P450 26A1 CYP26A1 0.0011
365 Dihydrofolate reductase DHFR 0.0011
2381 Dihydrofolate reductase DFR1 0.0011
2833 Dihydrofolate reductase Not Available 0.0011
2931 Dihydrofolate reductase folA 0.0011
3544 Dihydrofolate reductase folA 0.0011
3682 Dihydrofolate reductase folA 0.0011
6642 Dihydrofolate reductase folA 0.0011
6756 Dihydrofolate reductase dfrA 0.0011
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0011
754 Pancreatic triacylglycerol lipase PNLIP 0.0011
751 Potassium channel subfamily K member 6 KCNK6 0.0011
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0011
518 Peroxidase/catalase T katG 0.0011
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0011
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0011
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0011
6073 Potassium channel subfamily K member 9 KCNK9 0.0011
6072 Potassium channel subfamily K member 3 KCNK3 0.0011
1360 Sphingomyelin phosphodiesterase SMPD1 0.0011
2178 Metabotropic glutamate receptor 5 GRM5 0.0011
724 Interleukin-2 receptor alpha chain IL2RA 0.0011
717 Interleukin-2 receptor subunit beta IL2RB 0.0011
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.001
54 Prothrombin F2 0.001
1810 Protein S100-A1 S100A1 0.001
6097 Protein S100-A2 S100A2 0.001
4203 Histamine N-methyltransferase HNMT 0.001
4116 Dihydropteroate synthetase Not Available 0.001
4228 Keratin, type II cytoskeletal 7 KRT7 0.001
172 Potassium channel subfamily K member 1 KCNK1 0.001
1144 Hepatocyte growth factor receptor MET 0.001
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.001
493 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 0.001
512 DNA-directed RNA polymerase alpha chain rpoA 0.001
5772 DNA-directed RNA polymerase alpha chain rpoA 0.001
5300 Antigen peptide transporter 1 TAP1 0.001
4041 Microsomal glutathione S-transferase 2 MGST2 0.001
6824 Tyrosine-protein kinase Lyn LYN 0.001
2298 Cytochrome P450-cam camC 0.001
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0009
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0009
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0009
2268 Cholesterol oxidase choB 0.0009
2822 Cholesterol oxidase choA 0.0009
162 Retinoic acid receptor gamma-1 RARG 0.0009
6168 Solute carrier family 22 member 16 SLC22A16 0.0009
6042 Prostaglandin reductase 2 PTGR2 0.0009
6100 BDNF/NT-3 growth factors receptor NTRK2 0.0009
4773 Deoxycytidine kinase DCK 0.0009
1517 Beta-3 adrenergic receptor ADRB3 0.0009
6105 3-oxo-5-beta-steroid 4-dehydrogenase AKR1D1 0.0009
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0009
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0009
3086 Plasmepsin-2 Not Available 0.0009
1048 Protein S100-A13 S100A13 0.0009
2226 Protein S100-A12 S100A12 0.0009
1759 85 kDa calcium-independent phospholipase A2 PLA2G6 0.0009
1770 Phospholipase C PLCL1 0.0009
2841 Phospholipase C plc 0.0009
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0009
2283 Steroid Delta-isomerase ksi 0.0009
2920 Steroid Delta-isomerase ksi 0.0009
153 Dopamine beta-hydroxylase DBH 0.0009
208 DNA-directed RNA polymerase beta' chain rpoC 0.0009
5774 DNA-directed RNA polymerase beta' chain rpoC 0.0009
1792 Tissue-type plasminogen activator PLAT 0.0009
390 Adenosine A3 receptor ADORA3 0.0009
6169 ATP-binding cassette sub-family A member 5 ABCA5 0.0009
2132 Protein S100-B S100B 0.0009
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0008
3404 Exotoxin A eta 0.0008
1184 Interferon beta IFNB1 0.0008
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0008
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0008
22 30S ribosomal protein S4 rpsD 0.0008
6714 30S ribosomal protein S4 rpsD 0.0008
6122 Carbonic anhydrase 3 CA3 0.0008
2325 Sulfotransferase family cytosolic 2B member 1 SULT2B1 0.0008
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0008
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0008
1867 Major prion protein PRNP 0.0008
2232 Interleukin-5 IL5 0.0008
1593 Mucin-2 MUC2 0.0008
4031 Glutathione S-transferase A1 GSTA1 0.0008
4925 Cytochrome c-type protein SHP shp 0.0008
4943 Cytochrome c6 petJ 0.0008
4916 Cyanoglobin glbN 0.0008
4954 Soluble cytochrome b558 Not Available 0.0008
4994 Hemoglobin-like protein HbO glbO 0.0008
4915 Cytochrome c-550 psbV 0.0008
4959 Cytochrome c-550 psbV 0.0008
5216 Cytochrome c-550 psbV 0.0008
4934 Cytochrome c-551 nirM 0.0008
5218 Cytochrome c-551 nirM 0.0008
4905 Cytochrome c2 Not Available 0.0008
4939 Cytochrome c2 cycA 0.0008
4964 Cytochrome c2 cycA 0.0008
4979 Cytochrome c2 cycA 0.0008
6673 Cytochrome c2 cycA 0.0008
4984 Neuroglobin NGB 0.0008
4947 Bacterial hemoglobin vhb 0.0008
4975 Cytochrome c-556 RPA3973 0.0008
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0008
4936 Cytochrome c2 iso-2 Not Available 0.0008
4981 Iron-starvation protein PigA pigA 0.0008
4942 Diheme cytochrome c napB napB 0.0008
3116 Bacterioferritin bfr 0.0008
4906 Bacterioferritin bfr 0.0008
4965 Bacterioferritin bfr 0.0008
4909 CooA protein cooA 0.0008
4907 Cytochrome c-L moxG 0.0008
6865 Cytochrome c-L moxG 0.0008
4998 Hemoglobin-like protein yjbI yjbI 0.0008
4910 Cytoglobin CYGB 0.0008
4961 Hemophore HasA hasA 0.0008
5000 HemO hemO 0.0008
644 Heme oxygenase 2 HMOX2 0.0008
4982 Heme oxygenase 2 pbsA2 0.0008
4976 Apocytochrome f petA 0.0008
6407 Apocytochrome f petA 0.0008
4971 Nonaheme cytochrome c hmcA 0.0008
4904 Cytochrome c family protein GSU1996 0.0008
4935 Cytochrome c-554 cycA1 0.0008
4972 P450cin cinA 0.0008
4926 Heme-based aerotactic transducer hemAT hemAT 0.0008
4960 Putative cytochrome P450-family protein SCO7417 0.0008
4931 Cytochrome P450 167A1 CYP167A1 0.0008
4764 Cytochrome P450 165C4 CYP165C4 0.0008
4989 Cytochrome c551 peroxidase ccp 0.0008
5222 Cytochrome c551 peroxidase ccpA 0.0008
4999 Cytochrome P450 165B3 CYP165B3 0.0008
4937 Cytochrome oxidase subunit II rcoxA 0.0008
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0008
4903 Methyl-accepting chemotaxis protein Tar4 0.0008
4993 Hydroxylamine oxidoreductase hao1 0.0008
4952 Catalase/peroxidase katA 0.0008
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0008
4922 Cytochrome c, putative SO_4144 0.0008
3093 Catalase HPII katE 0.0008
1649 Small inducible cytokine A2 CCL2 0.0008
6163 Copper-transporting ATPase 2 ATP7B 0.0008
6165 Copper-transporting ATPase 1 ATP7A 0.0008
1025 Aquaporin-1 AQP1 0.0008
3856 Fibroblast growth factor receptor 3 FGFR3 0.0008
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0008
2091 Endoplasmin HSP90B1 0.0008
6893 Calcium/calmodulin-dependent protein kinase type II gamma chain CAMK2G 0.0007
473 L-lactate dehydrogenase A chain LDHA 0.0007
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0007
461 Glycine receptor subunit alpha-3 GLRA3 0.0007
1313 Lactoylglutathione lyase GLO1 0.0007
620 Bifunctional dihydrofolate reductase-thymidylate synthase Not Available 0.0007
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0007
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0007
2112 Toll-like receptor 9 TLR9 0.0007
6207 30S ribosomal protein S14 rpsN 0.0007
6209 30S ribosomal protein S19 rpsS 0.0007
6712 30S ribosomal protein S19 rpsS 0.0007
6726 30S ribosomal protein S19 rpsS 0.0007
645 Penicillin-binding protein 1A mrcA 0.0007
5805 Penicillin-binding protein 1A ponA 0.0007
6185 Penicillin-binding protein 1A mrcA 0.0007
6799 Penicillin-binding protein 1A pbpA 0.0007
5924 Microtubule-associated protein 4 MAP4 0.0007
5923 Microtubule-associated protein tau MAPT 0.0007
2290 ADP-ribosyl cyclase 2 BST1 0.0007
24 Thymidylate synthase TMP1 0.0007
359 Thymidylate synthase TYMS 0.0007
2626 Thymidylate synthase thyA 0.0007
2729 Thymidylate synthase thyA 0.0007
5352 Thymidylate synthase THYA 0.0007
226 Gonadotropin-releasing hormone receptor GNRHR 0.0007
1830 5'-nucleotidase NT5E 0.0007
4666 Fucose-binding lectin PA-IIL lecB 0.0007
2372 Bifunctional tail protein 9 0.0007
164 Histamine H4 receptor HRH4 0.0007
125 DNA polymerase beta POLB 0.0007
4311 tRNA TRDMT1 0.0007
4325 tRNA trmD 0.0007
4328 tRNA trmD 0.0007
1123 Eosinophil cationic protein RNASE3 0.0007
2599 Tyrosine-protein kinase HCK HCK 0.0007
4878 Glycoprotein hormones alpha chain CGA 0.0006
1052 Cytotoxic T-lymphocyte protein 4 CTLA4 0.0006
1072 Granzyme B GZMB 0.0006
4871 Endo-beta-N-acetylglucosaminidase F3 endOF3 0.0006
4880 Membrane cofactor protein CD46 0.0006
4889 Ig epsilon chain C region IGHE 0.0006
4877 Beta-mannanase man 0.0006
1563 Platelet glycoprotein Ib alpha chain GP1BA 0.0006
4850 Beta-2-glycoprotein 1 APOH 0.0006
4856 CD209 antigen CD209 0.0006
4189 Alpha-galactosidase A GLA 0.0006
4869 Major capsid protein A430L 0.0006
757 Fusion glycoprotein F0 F 0.0006
4875 Fusion glycoprotein F0 F 0.0006
4852 Reticulon-4 receptor RTN4R 0.0006
4845 ADAM 33 ADAM33 0.0006
1354 Beta-glucuronidase GUSB 0.0006
442 Envelope glycoprotein gp41 0.0006
4859 Envelope glycoprotein env 0.0006
4882 Dipeptidyl aminopeptidase-like protein 6 DPP6 0.0006
4721 Beta-1,4-mannanase manA 0.0006
3352 Structural polyprotein Not Available 0.0006
3628 Structural polyprotein Not Available 0.0006
4892 Structural polyprotein Not Available 0.0006
144 Hemoglobin subunit alpha HBA1 0.0006
6174 50S ribosomal protein L32 rpmF 0.0006
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0006
215 Sodium channel protein type 11 subunit alpha SCN11A 0.0006
1196 Complement decay-accelerating factor CD55 0.0006
3426 Glutamine synthetase glnA 0.0006
3987 Glutamine synthetase GLUL 0.0006
890 Niemann-Pick C1-like protein 1 NPC1L1 0.0006
3126 Poly [ADP-ribose] polymerase 1 PARP1 0.0006
4920 Peroxidase/catalase katG 0.0006
6167 Organic solute transporter subunit beta OSTB 0.0006
6166 Organic solute transporter subunit alpha OSTA 0.0006
4948 Cytochrome c-553 Not Available 0.0006
4923 Cytochrome c3 DvMF_2499 0.0006
4945 Cytochrome c3 Not Available 0.0006
4949 Cytochrome c3 DVU_3171 0.0006
4968 Cytochrome c3 cytc3 0.0006
4997 Cytochrome c3 SO_2727 0.0006
5219 Cytochrome c3 cyd 0.0006
2119 Cytochrome b5 CYB5A 0.0006
4902 Nine-heme cytochrome c Ddes_2038 0.0006
3189 High-molecular-weight cytochrome c hmcA 0.0006
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0006
4990 PpcA ppcA 0.0006
3611 Cytidine deaminase cdd 0.0006
3707 Cytidine deaminase cdd 0.0006
4211 Cytidine deaminase CDA 0.0006
3375 Acidic cytochrome c3 Not Available 0.0006
4037 Hypothetical protein GPX1 0.0006
4297 Hypothetical protein SP_1951 0.0006
4521 Hypothetical protein BC_2969 0.0006
4540 Hypothetical protein TM_1070 0.0006
4555 Hypothetical protein MT1739 0.0006
4569 Hypothetical protein mshD 0.0006
4578 Hypothetical protein PA3270 0.0006
4747 Hypothetical protein PA3967 0.0006
5177 Hypothetical protein TM_0096 0.0006
5194 Hypothetical protein PA1204 0.0006
5240 Hypothetical protein Rv2991 0.0006
5370 Hypothetical protein TM_1158 0.0006
5710 Hypothetical protein Tb927.5.1360 0.0006
4988 Sulfite oxidase, mitochondrial SUOX 0.0006
2915 Sensor protein fixL fixL 0.0006
4944 Sensor protein fixL fixL 0.0006
3570 Cytochrome P450 152A1 cypC 0.0006
4289 Cytochrome P450 TT_P0059 0.0006
6262 Cytochrome P450 staP 0.0006
4992 Cytochrome c peroxidase Not Available 0.0006
4385 Cytochrome c' Not Available 0.0006
4967 Cytochrome c' cycA 0.0006
5038 Cytochrome c' Not Available 0.0006
5223 Cytochrome c' cycP 0.0006
4813 Heme oxygenase hmuO 0.0006
5769 Heme oxygenase Not Available 0.0006
1291 cAMP response element-binding protein CREB1 0.0006
1569 G1/S-specific cyclin-D1 CCND1 0.0006
4193 Atrial natriuretic peptide clearance receptor NPR3 0.0006
793 T-cell surface antigen CD2 CD2 0.0006
4861 Interleukin-6 receptor alpha chain IL6R 0.0006
119 Carcinoembryonic antigen-related cell adhesion molecule 1 CEACAM1 0.0006
3837 Cytokine receptor common beta chain CSF2RB 0.0006
1525 Heparin-binding growth factor 2 FGF2 0.0006
2230 Catalase CAT 0.0006
3249 Catalase katA 0.0006
3625 Catalase katA 0.0006
4539 Catalase katA 0.0006
4941 Catalase katB 0.0006
2430 Chondroitinase B cslB 0.0005
4210 Toll-like receptor 4 TLR4 0.0005
2808 Chloramphenicol acetyltransferase 3 cat3 0.0005
1341 Histamine H3 receptor HRH3 0.0005
1760 Aminopeptidase N ANPEP 0.0005
6843 Aminopeptidase N pepN 0.0005
117 Sterol O-acyltransferase 1 SOAT1 0.0005
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0005
244 Angiotensin-converting enzyme ACE 0.0005
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0005
6211 Tubulin epsilon chain TUBE1 0.0005
6212 Tubulin gamma-1 chain TUBG1 0.0005
6210 Tubulin delta chain TUBD1 0.0005
3411 Cytochrome P450 121 cyp121 0.0005
3670 Soluble cytochrome b562 precursor cybC 0.0005
2617 Nitric oxide synthase oxygenase nos 0.0005
2701 Nitric oxide synthase oxygenase nos 0.0005
3291 Cytochrome c-552 cycA 0.0005
4927 Cytochrome c-552 nrfA 0.0005
4938 Cytochrome c-552 cycA 0.0005
4953 Cytochrome c-552 nrfA 0.0005
5217 Cytochrome c-552 cycM 0.0005
3810 Catechol O-methyltransferase COMT 0.0005
4386 Hemoglobin-like protein HbN glbN 0.0005
3102 Flavohemoprotein hmp 0.0005
4969 Flavohemoprotein hmp 0.0005
2417 Chloramphenicol acetyltransferase cat 0.0005
3278 Chloramphenicol acetyltransferase cat 0.0005
1379 Interleukin-12 subunit beta IL12B 0.0005
2810 Dr hemagglutinin structural subunit draA 0.0005
4890 Hemagglutinin HA 0.0005
6566 Hemagglutinin Not Available 0.0005
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0005
4857 Zinc-alpha-2-glycoprotein AZGP1 0.0005
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.0005
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0005
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0005
6858 Inactive carboxylesterase 4 CES1P1 0.0005
6120 Cation-independent mannose-6-phosphate receptor IGF2R 0.0005
3127 Nitrite reductase nirS 0.0005
3284 Nitrite reductase nirS 0.0005
3913 Glutamic acid decarboxylase GAD65 0.0005
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0005
18 High affinity immunoglobulin epsilon receptor subunit alpha FCER1A 0.0005
3221 Cytochrome c4 cc4 0.0005
554 Low-density lipoprotein receptor LDLR 0.0004
852 Heparin cofactor 2 SERPIND1 0.0004
2972 6-deoxyerythronolide B hydroxylase eryF 0.0004
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0004
476 RAC-alpha serine/threonine-protein kinase AKT1 0.0004
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0004
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0004
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0004
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0004
4608 Putative cytochrome P450 SCO1207 0.0004
4963 Putative cytochrome P450 SCO2884 0.0004
6254 Putative cytochrome P450 SCO6998 0.0004
1859 Prostatic acid phosphatase ACPP 0.0004
595 Fibrinogen alpha chain FGA 0.0004
3140 Hemagglutinin-neuraminidase HN 0.0004
3609 Hemagglutinin-neuraminidase HN 0.0004
3444 Cyanovirin-N Not Available 0.0004
3258 Mannosyl-oligosaccharide alpha-1,2-mannosidase MSDC 0.0004
976 Platelet glycoprotein IX GP9 0.0004
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0004
358 Cystathionine beta-synthase CBS 0.0004
935 Proto-oncogene tyrosine-protein kinase Yes YES1 0.0004
1063 Signal transducer and activator of transcription 5B STAT5B 0.0004
2216 Fibroblast growth factor receptor 4 FGFR4 0.0004
4217 Telomerase reverse transcriptase TERT 0.0004
693 Hemoglobin subunit beta HBB 0.0004
735 Alanine aminotransferase 1 GPT 0.0004
3904 Alanine aminotransferase 2 GPT2 0.0004
4509 Acetoin(diacetyl) reductase budC 0.0004
1176 Mitogen-activated protein kinase 1 MAPK1 0.0004
958 Insulin-like growth factor 1 receptor IGF1R 0.0004
6268 Hydroxyacid oxidase 1 HAO1 0.0004
594 Thyroxine-binding globulin SERPINA7 0.0004
3689 Endoglucanase A celA 0.0004
3814 Complement C1r subcomponent C1R 0.0004
3009 Beta-glucanase Not Available 0.0004
5411 Slt-IIvB stxB2e 0.0004
5565 Inorganic polyphosphate/ATP-glucomannokinase ppgmk 0.0004
5563 Galectin-2 LGALS2 0.0004
1875 Pulmonary surfactant-associated protein D SFTPD 0.0004
5569 Endo-1,4-beta glucanase EngF engF 0.0004
5046 Ecotin eco 0.0004
3793 Aspartate ammonia-lyase aspA 0.0004
5554 D-galactose-binding periplasmic protein mglB 0.0004
3741 D-galactose-binding periplasmic protein precursor mglB 0.0004
5568 Endoglucanase C307 celC307 0.0004
5553 Endoglucanase E1 Acel_0614 0.0004
5562 Hexokinase Not Available 0.0004
3744 Endoglucanase SS precursor celS 0.0004
5570 Endoglucanase E-4 celD 0.0004
5559 Neopullulanase nplT 0.0004
4670 Cellulase B celB 0.0004
4668 Laminarinase TM_0024 0.0004
4667 BH0236 protein BH0236 0.0004
4671 Endoglucanase C cenC 0.0004
64 Neuraminidase NA 0.0004
641 Neuraminidase NA 0.0004
2676 Neuraminidase NA 0.0004
3026 Neuraminidase NA 0.0004
3519 Neuraminidase NA 0.0004
6007 Neuraminidase NA 0.0004
6048 Troponin C, skeletal muscle TNNC2 0.0004
934 Proto-oncogene tyrosine-protein kinase Fyn FYN 0.0004
810 Heme oxygenase 1 HMOX1 0.0004
3391 Heme oxygenase 1 pbsA1 0.0004
2577 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase MAN1B1 0.0004
1243 Cathepsin D CTSD 0.0003
268 Adenosine A2b receptor ADORA2B 0.0003
828 Phenylalanine-4-hydroxylase PAH 0.0003
3109 Phenylalanine-4-hydroxylase phhA 0.0003
6044 Serum paraoxonase/lactonase 3 PON3 0.0003
1439 Lactotransferrin LTF 0.0003
309 Antithrombin-III SERPINC1 0.0003
758 Thyroid hormone receptor alpha THRA 0.0003
1782 Neutrophil gelatinase-associated lipocalin LCN2 0.0003
484 Tyrosine-protein kinase ABL2 ABL2 0.0003
2240 Cell division protein kinase 2 CDK2 0.0003
5176 YtnJ moxC 0.0003
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0003
572 Integrin alpha-L ITGAL 0.0003
5416 Coat protein VP1 Not Available 0.0003
2705 Dimethyl sulfoxide reductase dmsA 0.0003
199 Monocarboxylate transporter 8 SLC16A2 0.0003
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0003
5247 Endo-1,4-beta-xylanase Not Available 0.0003
5248 Endo-1,4-beta-xylanase xlnA 0.0003
5250 Endo-1,4-beta-xylanase xyl 0.0003
4669 Endo-1,4-beta-xylanase A xynA 0.0003
4715 Endo-1,4-beta-xylanase A xlnA 0.0003
5560 Endo-1,4-beta-xylanase A xynA 0.0003
1503 Galectin-7 LGALS7 0.0003
5498 Maltoporin lamB 0.0003
5561 Maltoporin lamB 0.0003
5056 Maltooligosyltrehalose trehalohydrolase, putative treZ 0.0003
3525 ADP-ribose pyrophosphatase, mitochondrial NUDT9 0.0003
4622 Amylase Not Available 0.0003
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0003
2728 Glucan 1,4-alpha-maltotetraohydrolase amyP 0.0003
2320 Thymidine kinase, cytosolic TK1 0.0003
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0003
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0003
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0003
6307 Ig gamma-2 chain C region IGHG2 0.0003
2826 Glucose--fructose oxidoreductase gfo 0.0003
1881 Hexokinase-1 HK1 0.0003
2581 Chondroitinase AC cslA 0.0003
6847 Lactase-phlorizin hydrolase LCT 0.0003
346 Thyroid hormone receptor beta-1 THRB 0.0003
2324 Botulinum neurotoxin type B botB 0.0003
3153 Quinoprotein glucose dehydrogenase-B gdhB 0.0003
3747 Cellulase B precursor celB 0.0003
3547 Enterotoxin type B entB 0.0003
2856 Glucosamine-6-phosphate isomerase GNPDA1 0.0003
2564 Glucan 1,4-alpha-maltohexaosidase Not Available 0.0003
4819 Hydrolase Not Available 0.0003
5249 Hydrolase Not Available 0.0003
5436 Hydrolase Not Available 0.0003
2531 Alpha-amylase amyE 0.0003
2948 Alpha-amylase amy 0.0003
3169 Alpha-amylase Not Available 0.0003
2541 Neopullulanase 1 tvaI 0.0003
4811 Amylosucrase ams 0.0003
3091 Maltodextrin phosphorylase malP 0.0003
2606 Neopullulanase 2 tvaII 0.0003
760 Fibroblast growth factor 1 FGF1 0.0003
4692 A/G-specific adenine glycosylase mutY 0.0003
3225 Shiga toxin B-chain stxB 0.0003
3365 Beta-amylase spoII 0.0003
4830 Aldose 1-epimerase galM 0.0003
6614 Lactase-like protein LCTL 0.0003
6218 Pannexin-1 PANX1 0.0003
1675 Glucokinase GCK 0.0003
4662 Glucokinase glk 0.0003
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0003
3030 Salivary alpha-amylase AMY1A 0.0003
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.0003
2293 Cyclomaltodextrin glucanotransferase Not Available 0.0003
2508 Cyclomaltodextrin glucanotransferase cgt 0.0003
2523 Cyclomaltodextrin glucanotransferase cgt 0.0003
3207 Cyclomaltodextrin glucanotransferase amyA 0.0003
4272 POSSIBLE CELLULASE CELA1 celA1 0.0003
2570 Tetanus toxin tetX 0.0002
2448 Exoglucanase/xylanase [Includes: Exoglucanase cex 0.0002
3668 Maltose-binding periplasmic protein precursor malE 0.0002
2802 Endoglucanase G celCCG 0.0002
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0002
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0002
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0002
2440 Endoglucanase F celCCF 0.0002
2245 Xylose isomerase xylA 0.0002
2253 Xylose isomerase xylA 0.0002
2260 Xylose isomerase xylA 0.0002
2431 Xylose isomerase xylA 0.0002
3957 Adenosine deaminase ADA 0.0002
2252 Endoglucanase 5A cel5A 0.0002
6135 Sodium channel subunit beta-4 SCN4B 0.0002
6134 Sodium channel subunit beta-3 SCN3B 0.0002
6132 Sodium channel subunit beta-1 SCN1B 0.0002
6127 Carbonic anhydrase-related protein CA8 0.0002
6128 Carbonic anhydrase-related protein 10 CA10 0.0002
6133 Sodium channel subunit beta-2 SCN2B 0.0002
6129 Carbonic anhydrase-related protein 11 CA11 0.0002
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0002
10 Glycogen phosphorylase, liver form PYGL 0.0002
2723 Cholera enterotoxin subunit B ctxB 0.0002
4513 Pancreatic alpha-amylase AMY2A 0.0002
2427 Ferrichrome-iron receptor fhuA 0.0002
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.0002
6130 Carbonic anhydrase 13 CA13 0.0002
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0002
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0002
1152 Glycogen phosphorylase, muscle form PYGM 0.0002
3007 Carbonic anhydrase 12 CA12 0.0002
4205 Carbonic anhydrase 9 CA9 0.0002
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0001
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