Partner ID 4132
Name Chloride channel protein ClC-Ka
Synonyms 6612
Gene name CLCNKA
General function Involved in voltage-gated chloride channel activity
Specific function Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms
Gene sequence + ...

ATGGAGGAGTTGGTGGGGCTGCGTGAGGGCTTCTCAGGGGACCCTGTGACTCTGCAGGAGCTGTGGGGCCCCTGTCCCCACATCCGCCGAGCCATCCAAGGTGGCCTGGAGTGGCTAAAGCAGAAGGTGTTCCGCCTGGGAGAAGACTGGTACTTCCTGATGACCCTCGGGGTGCTCATGGCCCTGGTCAGCTATGCCATGAACTTTGCCATCGGGTGTGTGGTCCGAGCACACCAGTGGCTGTACAGGGAGATTGGGGACAGCCACCTGCTCCGGTATCTTTCCTGGACTGTGTACCCTGTGGCCCTCGTCTCTTTCTCCTCAGGCTTCTCCCAGAGCATCACGCCCTCCTCTGGAGGTTCTGGAATCCCGGAGCTGAAGACCATGTTGGCGGGTGTGATCTTGGAGGACTACCTGGATATCAAGAACTTTGGGGCCAAGGTGGTGGGCCTCTCCTGCACCCTGGCCACCGGCAGCACCCTGTTCCTGGGCAAAGTGGGCCCTTTCGTGCACCTGTCTGTAATGATCGCTGCCTACCTGGGCCGTGTGCGCACCACGACCATCGGGGAGCCTGAGAACAAGAGCAAGCAAAACGAAATGCTGGTGGCAGCGGCGGCAGTGGGCGTGGCCACAGTCTTTGCAGCTCCCTTCAGCGGCGTCCTGTTCAGCATCGAGGTCATGTCTTCCCACTTCTCTGTCCGGGATTACTGGAGGGGCTTCTTTGCGGCCACCTGCGGGGCCTTCATATTCCGGCTCCTGGCAGTCTTCAACAGCGAGCAGGAGACCATCACCTCCCTCTACAAGACCAGTTTCCGGGTGGACGTTCCCTTCGACCTGCCTGAGATCTTCTTTTTTGTGGCGCTGGGTGGCATCTGCGGCGTCCTGAGCTGTGCTTACCTCTTCTGTCAGCGAACCTTCCTCAGCTTCATCAAGACCAATCGGTACAGCTCCAAACTGCTGGCTACTAGCAAGCCTGTGTACTCCGCTCTGGCCACCTTGCTTCTCGCCTCCATCACCTACCCGCCTGGTGTGGGCCACTTCCTAGCTTCTCGGCTGTCCATGAAGCAGCATCTGGACTCGCTGTTCGACAACCACTCCTGGGCGCTGATGACCCAGAACTCCAGCCCACCCTGGCCCGAGGAGCTCGACCCCCAGCACCTTTGGTGGGAATGGTACCACCCGCGGTTCACCATCTTTGGGACCCTTGCCTTCTTCCTGGTTATGAAGTTCTGGATGCTGATTCTGGCCACCACCATCCCCATGCCTGCCGGGTACTTCATGCCCATCTTTATCCTTGGAGCTGCCATCGGGCGCCTCTTGGGAGAGGCTCTTGCCGTCGCCTTCCCTGAGGGCATTGTGACTGGAGGGGTTACCAATCCCATCATGCCCGGGGGGTATGCTCTGGCAGGGGCTGCAGCCTTCTCAGGGGCTGTGACCCACACCATCTCCACGGCGCTGCTGGCCTTTGAGCTGACCGGCCAGATAGTGCATGCACTGCCCGTGCTGATGGCGGTGCTGGCAGCCAACGCCATTGCACAGAGCTGCCAGCCCTCCTTCTATGATGGCACCATCATTGTCAAGAAGCTGCCATACCTGCCACGGATTCTGGGCCGCAACATCGGCTCCCACCATGTGAGGGTGGAGCACTTCATGAACCACAGCATCACCACACTGGCCAAGGACACGCCGCTGGAGGAGGTGGTCAAGGTTGTGACCTCCACAGACGTGACCGAGTATCCCCTGGTGGAGAGCACAGAGTCCCAGATCCTGGTAGGCATCGTGCAGAGGGCCCAGCTGGTGCAGGCCCTCCAGGCTGAGCCTCCTTCCAGGGCTCCAGGACACCAGCAGTGTCTCCAGGACATCTTGGCCAGGGGCTGCCCCACGGAACCAGTGACCCTGACGCTATTCTCAGAGACCACCTTGCACCAGGCACAAAACCTCTTTAAGCTGTTGAACCTTCAGTCCCTCTTCGTGACATCGCGGGGCAGAGCTGTGGGCTGCGTGTCCTGGGTGGAGATGAAGAAAGCAATTTCCAACCTGACAAATCCGCCAGCTCCAAAGTGA

Protein sequence + ...

MEELVGLREGFSGDPVTLQELWGPCPHIRRAIQGGLEWLKQKVFRLGEDWYFLMTLGVLMALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYLGRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGFFAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYLFCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGVGHFLASRLSMKQHLDSLFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTHTISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNIGSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLVESTESQILVGIVQRAQLVQALQAEPPSRAPGHQQCLQDILARGCPTEPVTLTLFSETTLHQAQNLFKLLNLQSLFVTSRGRAVGCVSWVEMKKAISNLTNPPAPK

GO Classification
component
membrane
cell
function
voltage-gated chloride channel activity
transporter activity
ion transporter activity
ion channel activity
voltage-gated ion channel activity
process
ion transport
anion transport
inorganic anion transport
chloride transport
physiological process
cellular physiological process
transport
See more information at   →   www.drugbank.ca
Id Name
DB04552 Niflumic Acid
Id Name
DB00005 Etanercept
DB00035 Desmopressin
DB00041 Aldesleukin
DB00062 Human Serum Albumin
DB00086 Streptokinase
DB00119 Pyruvic acid
DB00142 L-Glutamic Acid
DB00154 gamma-Homolinolenic acid
DB00159 Icosapent
DB00175 Pravastatin
DB00188 Bortezomib
DB00197 Troglitazone
DB00214 Torasemide
DB00216 Eletriptan
DB00233 Aminosalicylic Acid
DB00244 Mesalazine
DB00250 Dapsone
DB00313 Valproic Acid
DB00316 Acetaminophen
DB00327 Hydromorphone
DB00328 Indomethacin
DB00345 Aminohippurate
DB00350 Minoxidil
DB00360 Tetrahydrobiopterin
DB00398 Sorafenib
DB00402 Eszopiclone
DB00411 Carbachol
DB00412 Rosiglitazone
DB00415 Ampicillin
DB00425 Zolpidem
DB00445 Epirubicin
DB00461 Nabumetone
DB00465 Ketorolac
DB00469 Tenoxicam
DB00470 Dronabinol
DB00471 Montelukast
DB00480 Lenalidomide
DB00482 Celecoxib
DB00494 Entacapone
DB00500 Tolmetin
DB00502 Haloperidol
DB00515 Cisplatin
DB00529 Foscarnet
DB00533 Rofecoxib
DB00540 Nortriptyline
DB00549 Zafirlukast
DB00554 Piroxicam
DB00563 Methotrexate
DB00573 Fenoprofen
DB00578 Carbenicillin
DB00580 Valdecoxib
DB00582 Voriconazole
DB00586 Diclofenac
DB00588 Fluticasone Propionate
DB00591 Fluocinolone Acetonide
DB00605 Sulindac
DB00619 Imatinib
DB00620 Triamcinolone
DB00627 Niacin
DB00672 Chlorpropamide
DB00688 Mycophenolate mofetil
DB00711 Diethylcarbamazine
DB00712 Flurbiprofen
DB00720 Clodronate
DB00731 Nateglinide
DB00744 Zileuton
DB00749 Etodolac
DB00762 Irinotecan
DB00773 Etoposide
DB00784 Mefenamic acid
DB00788 Naproxen
DB00795 Sulfasalazine
DB00796 Candesartan
DB00812 Phenylbutazone
DB00814 Meloxicam
DB00818 Propofol
DB00821 Carprofen
DB00829 Diazepam
DB00842 Oxazepam
DB00856 Chlorphenesin
DB00857 Terbinafine
DB00861 Diflunisal
DB00870 Suprofen
DB00884 Risedronate
DB00887 Bumetanide
DB00921 Buprenorphine
DB00936 Salicyclic acid
DB00939 Meclofenamic acid
DB00945 Acetylsalicylic acid
DB00963 Bromfenac
DB00991 Oxaprozin
DB01009 Ketoprofen
DB01014 Balsalazide
DB01015 Sulfamethoxazole
DB01024 Mycophenolic acid
DB01029 Irbesartan
DB01032 Probenecid
DB01041 Thalidomide
DB01050 Ibuprofen
DB01075 Diphenhydramine
DB01083 Orlistat
DB01103 Quinacrine
DB01132 Pioglitazone
DB01136 Carvedilol
DB01181 Ifosfamide
DB01198 Zopiclone
DB01221 Ketamine
DB01283 Lumiracoxib
DB01355 Hexobarbital
DB01395 Drospirenone
DB01397 Magnesium salicylate
DB01398 Salicylate-sodium
DB01399 Salsalate
DB01401 Trisalicylate-choline
DB01404 Ginseng
DB01419 Antrafenine
DB01435 Antipyrine
DB01440 Gamma Hydroxybutyric Acid
DB01600 Tiaprofenic acid
DB01628 Etoricoxib
DB01762 Acetoacetic Acid
DB01837 O-Acetylserine
DB01892 Hyperforin
DB02047 2-(1,1'-Biphenyl-4-Yl)Propanoic Acid
DB02110 Protoporphyrin Ix Containing Co
DB02198 2-Bromoacetyl Group
DB02210 Hexane-1,6-Diol
DB02266 Flufenamic Acid
DB02379 Beta-D-Glucose
DB02448 N-Tridecanoic Acid
DB02659 Cholic Acid
DB02687 Beta-D-Mannose
DB02709 Resveratrol
DB02773 (3-Chloro-4-Propoxy-Phenyl)-Acetic Acid
DB02795 P-Anisic Acid
DB02938 Heptanoic Acid
DB02944 Alpha-D-Mannose
DB03014 Heme
DB03066 D-Lactic Acid
DB03166 Acetic acid
DB03477 1-Phenylsulfonamide-3-Trifluoromethyl-5-Parabromophenylpyrazole
DB03565 1-O-Octyl-2-Heptylphosphonyl-Sn-Glycero-3-Phosphoethanolamine
DB03587 Pyruvoyl Group
DB03633 Lpc-Ether
DB03667 Acetic Acid Salicyloyl-Amino-Ester
DB03752 P-(2'-Iodo-5'-Thenoyl)Hydrotropic Acid
DB03753 Flurbiprofen Methyl Ester
DB03783 Phenacetin
DB03793 Benzoic Acid
DB03866 Prostaglandin G2
DB04074 Alpha-ketoisovalerate
DB04216 Quercetin
DB04319 6-Deoxyglucose
DB04348 Taurocholic Acid
DB04398 Lactic Acid
DB04552 Niflumic Acid
DB04557 Arachidonic Acid
DB04743 Nimesulide
DB04786 Suramin
DB04817 Dipyrone
DB04824 Phenolphthalein
DB04827 Ethyl carbamate
DB04953 Ezogabine
DB05109 Trabectedin
DB06204 Tapentadol
DB06695 Dabigatran etexilate
DB06725 Lornoxicam
DB06802 Nepafenac
DB06804 Nonoxynol-9
DB07657 PHOSPHONIC ACID 2-DODECANOYLAMINO-HEXYL ESTER PROPYL ESTER
DB07836 1-DECYL-3-TRIFLUORO ETHYL-SN-GLYCERO-2-PHOSPHOMETHANOL
DB07981 2-[1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYL-1H-INDOL-3-YL]-N-[(1R)-1-(HYDROXYMETHYL)PROPYL]ACETAMIDE
DB07983 1-(4-IODOBENZOYL)-5-METHOXY-2-METHYL INDOLE-3-ACETIC ACID
DB07984 2-[1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYL-1H-INDOL-3-YL]-N-[(1S)-1-(HYDROXYMETHYL)PROPYL]ACETAMIDE
DB08814 Triflusal
DB08819 Tafluprost
DB08896 Regorafenib
DB08907 Canagliflozin
DB08910 Pomalidomide