DT-Web

DB03783 - Phenacetin


Identification
Name Phenacetin
Accession Number DB03783 (DB08243, EXPT03306)
Type small molecule
Description Phenacetin was withdrawn from the Canadian market in June 1973 due to concerns regarding nephropathy (damage to or disease of the kidney).
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 179.2157
Groups withdrawn
Monoisotopic Weight 179.094628665
Pharmacology
Indication Used principally as an analgesic.
Mechanism of action Phenacetin's analgesic effects are due to its actions on the sensory tracts of the spinal cord. In addition, phenacetin has a depressant action on the heart, where it acts as a negative inotrope. It is an antipyretic, acting on the brain to decrease the temperature set point. It is also used to treat rheumatoid arthritis (subacute type) and intercostal neuralgia. [Wikipedia]
Absorption Not Available
Protein binding Not Available
Biotransformation Metabolised in the body to paracetamol.
Route of elimination Not Available
Toxicity Acute oral toxicity (LD50): 866 mg/kg [Mouse].
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Prostaglandin G/H synthase 1
Name Prostaglandin G/H synthase 1
Gene Name PTGS1
Pharmacological action unknown
Actions Not Available
References
  • Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. - Pubmed
DTHybrid score 0.5247

Enzymes


Cytochrome P450 1A2
Name Cytochrome P450 1A2
Gene Name CYP1A2
Actions substrate
References
  • Flockhart DA. - Drug Interactions: Cytochrome P450 Drug Interaction Table
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
  • Zhang T, Zhu Y, Gunaratna C: Rapid and quantitative determination of metabolites from multiple cytochrome P450 probe substrates by gradient liquid chromatography-electrospray ionization-ion trap mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Nov 25;780(2):371-9. - Pubmed
  • Kobayashi K, Nakajima M, Oshima K, Shimada N, Yokoi T, Chiba K: Involvement of CYP2E1 as A low-affinity enzyme in phenacetin O-deethylation in human liver microsomes. Drug Metab Dispos. 1999 Aug;27(8):860-5. - Pubmed
DTHybrid score 0.6069
Cytochrome P450 2D6
Name Cytochrome P450 2D6
Gene Name CYP2D6
Actions substrate
References
  • Flockhart DA. - Drug Interactions: Cytochrome P450 Drug Interaction Table
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.5744
Cytochrome P450 1A1
Name Cytochrome P450 1A1
Gene Name CYP1A1
Actions substrate
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.3737
Cytochrome P450 2A13
Name Cytochrome P450 2A13
Gene Name CYP2A13
Actions substrate
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.1739
Cytochrome P450 2A6
Name Cytochrome P450 2A6
Gene Name CYP2A6
Actions substrate
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.4297
Cytochrome P450 2C19
Name Cytochrome P450 2C19
Gene Name CYP2C19
Actions substrate
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.5227
Cytochrome P450 2C9
Name Cytochrome P450 2C9
Gene Name CYP2C9
Actions substrate
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.6182
Cytochrome P450 2E1
Name Cytochrome P450 2E1
Gene Name CYP2E1
Actions substrate
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.3969
Cytochrome P450 3A4
Name Cytochrome P450 3A4
Gene Name CYP3A4
Actions substrate
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.7676

Transporters


Solute carrier family 22 member 6
Name Solute carrier family 22 member 6
Gene Name SLC22A6
Actions inhibitor
References
  • Mulato AS, Ho ES, Cihlar T: Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1. J Pharmacol Exp Ther. 2000 Oct;295(1):10-5. - Pubmed
  • Apiwattanakul N, Sekine T, Chairoungdua A, Kanai Y, Nakajima N, Sophasan S, Endou H: Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes. Mol Pharmacol. 1999 May;55(5):847-54. - Pubmed
DTHybrid score 0.3244

Predictions


Id Partner name Gene Name Score
4924 Cytochrome P450 2C8 CYP2C8 0.3274
1588 Multidrug resistance protein 1 ABCB1 0.2796
6030 Cytochrome P450 2B6 CYP2B6 0.2447
4118 Cytochrome P450 3A5 CYP3A5 0.2376
290 Prostaglandin G/H synthase 2 PTGS2 0.218
6107 Cytochrome P450 3A7 CYP3A7 0.1717
587 Serum albumin ALB 0.1494
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.1071
6142 Solute carrier family 22 member 8 SLC22A8 0.0985
492 Histamine H1 receptor HRH1 0.0887
6106 Cytochrome P450 2C18 CYP2C18 0.0835
1898 Cytochrome P450 1B1 CYP1B1 0.0757
3811 Cytochrome P450 19A1 CYP19A1 0.0722
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0705
6145 Solute carrier family 22 member 1 SLC22A1 0.0694
824 Sodium-dependent serotonin transporter SLC6A4 0.069
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0667
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0646
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.064
1024 Solute carrier family 22 member 11 SLC22A11 0.0639
6143 Solute carrier family 22 member 7 SLC22A7 0.0635
118 Organic cation/carnitine transporter 2 SLC22A5 0.0627
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0617
6144 Solute carrier family 22 member 2 SLC22A2 0.0607
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0597
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0573
862 Multidrug resistance-associated protein 1 ABCC1 0.0573
502 5-hydroxytryptamine 2A receptor HTR2A 0.0561
3941 Amine oxidase [flavin-containing] A MAOA 0.055
831 D(2) dopamine receptor DRD2 0.0549
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0538
556 Alpha-1A adrenergic receptor ADRA1A 0.0534
766 Beta-2 adrenergic receptor ADRB2 0.0511
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0506
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0492
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0484
2164 Multidrug resistance-associated protein 4 ABCC4 0.048
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0477
6147 Solute carrier family 22 member 3 SLC22A3 0.045
776 Bile salt export pump ABCB11 0.0447
318 Alpha-2A adrenergic receptor ADRA2A 0.0432
833 Organic cation/carnitine transporter 1 SLC22A4 0.043
590 5-hydroxytryptamine 2C receptor HTR2C 0.0418
136 Estrogen receptor ESR1 0.0407
193 Beta-1 adrenergic receptor ADRB1 0.0405
713 Sodium-dependent dopamine transporter SLC6A3 0.0401
341 5-hydroxytryptamine 3 receptor HTR3A 0.0396
320 5-hydroxytryptamine 1A receptor HTR1A 0.0393
275 Arachidonate 5-lipoxygenase ALOX5 0.0391
617 Muscarinic acetylcholine receptor M2 CHRM2 0.039
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.039
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0381
468 Cytochrome P450 4A11 CYP4A11 0.038
23 D(1A) dopamine receptor DRD1 0.0378
260 Cytochrome P450 51 ERG11 0.0377
761 Cytochrome P450 51 ERG11 0.0377
3163 Cytochrome P450 51 cyp51 0.0377
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0374
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0368
3939 Amine oxidase [flavin-containing] B MAOB 0.0367
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0362
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0361
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0358
6031 Cytochrome P450 3A43 CYP3A43 0.0356
817 DNA topoisomerase 2-alpha TOP2A 0.0336
632 Alpha-1B adrenergic receptor ADRA1B 0.0334
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0326
404 DNA gyrase subunit A gyrA 0.0318
6224 DNA gyrase subunit A gyrA 0.0318
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0317
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0311
871 Glucocorticoid receptor NR3C1 0.0307
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0298
885 5-hydroxytryptamine 1B receptor HTR1B 0.0296
847 Mu-type opioid receptor OPRM1 0.0296
465 Calmodulin CALM1 0.0292
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0292
731 HIV-1 protease HIV-1 protease 0.0291
1757 Myeloperoxidase MPO 0.029
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0289
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0287
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0284
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0284
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.028
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.0276
146 Androgen receptor AR 0.0275
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0268
592 Carbonic anhydrase 4 CA4 0.0266
295 Carbonic anhydrase 1 CA1 0.0264
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0259
36 Insulin receptor INSR 0.0258
777 Tumor necrosis factor TNF 0.0258
6102 Arylamine N-acetyltransferase 2 NAT2 0.0257
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0253
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0252
467 Delta-type opioid receptor OPRD1 0.025
638 D(3) dopamine receptor DRD3 0.0248
477 DNA topoisomerase 4 subunit A parC 0.0246
886 DNA topoisomerase 4 subunit A parC 0.0246
6226 DNA topoisomerase 4 subunit A parC 0.0246
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.0244
373 Transthyretin TTR 0.024
891 Dihydropteroate synthase folP 0.0239
5359 Dihydropteroate synthase folP 0.0239
7175 Dihydropteroate synthase sulI 0.0239
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0239
696 Kappa-type opioid receptor OPRK1 0.0237
725 5-hydroxytryptamine 1D receptor HTR1D 0.0236
6141 Sodium/bile acid cotransporter SLC10A1 0.0234
789 Alpha-1D adrenergic receptor ADRA1D 0.0234
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0233
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0232
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0232
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0231
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0227
3923 Cholinesterase BCHE 0.0226
629 Alpha-2B adrenergic receptor ADRA2B 0.0223
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.021
357 Carbonic anhydrase 2 CA2 0.0208
122 P2Y purinoceptor 12 P2RY12 0.0208
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0206
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.0203
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0203
442 Envelope glycoprotein gp41 0.0198
4859 Envelope glycoprotein env 0.0198
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0198
378 Alpha-2C adrenergic receptor ADRA2C 0.0196
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0195
70 Type-1 angiotensin II receptor AGTR1 0.0192
738 Monocarboxylate transporter 1 SLC16A1 0.0191
16 Adenosine A1 receptor ADORA1 0.0191
80 Peroxisome proliferator-activated receptor alpha PPARA 0.019
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.019
6012 Tryptophan 2,3-dioxygenase TDO2 0.019
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.019
6136 Multidrug resistance-associated protein 5 ABCC5 0.0189
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0185
633 Penicillin-binding proteins 1A/1B pbpA 0.0185
432 D(4) dopamine receptor DRD4 0.0183
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0182
482 Glycine receptor subunit alpha-1 GLRA1 0.0182
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.018
756 Sex hormone-binding globulin SHBG 0.0179
6148 Multidrug resistance-associated protein 7 ABCC10 0.0179
613 Atrial natriuretic peptide receptor A NPR1 0.0179
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0178
436 5-hydroxytryptamine 2B receptor HTR2B 0.0177
6220 Aryl hydrocarbon receptor AHR 0.0176
6126 Carbonic anhydrase 7 CA7 0.0176
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0174
811 Translocator protein TSPO 0.0174
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0173
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0173
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0173
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.017
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0169
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0169
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0166
1178 Adenosine A2a receptor ADORA2A 0.0164
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0161
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0159
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0158
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.0158
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0158
3932 Glutathione S-transferase A2 GSTA2 0.0157
1010 Cytochrome P450 51A1 CYP51A1 0.0156
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0155
3947 Xanthine dehydrogenase/oxidase XDH 0.0154
380 Cytochrome P450 17A1 CYP17A1 0.0153
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0153
723 Cytosolic phospholipase A2 PLA2G4A 0.0153
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0153
716 5-hydroxytryptamine 7 receptor HTR7 0.015
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.015
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0149
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0149
6182 Cytochrome P450 2J2 CYP2J2 0.0148
94 5-hydroxytryptamine 4 receptor HTR4 0.0148
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0148
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0147
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0147
241 Calcium-transporting ATPase type 2C member 1 ATP2C1 0.0146
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0145
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0143
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0141
3639 Thymidine phosphorylase deoA 0.014
3936 Thymidine phosphorylase TYMP 0.014
4604 Liver carboxylesterase 1 CES1 0.014
844 Epidermal growth factor receptor EGFR 0.014
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0139
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0139
537 ATP synthase delta chain, mitochondrial ATP5D 0.0138
705 Glutamate receptor 1 GRIA1 0.0137
571 Melatonin receptor type 1A MTNR1A 0.0136
362 Melatonin receptor type 1B MTNR1B 0.0136
68 Cannabinoid receptor 1 CNR1 0.0135
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.0134
6043 Putative G-protein coupled receptor 44 GPR44 0.0134
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0134
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0134
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0133
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0132
6137 Multidrug resistance-associated protein 6 ABCC6 0.013
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.013
124 Histamine H2 receptor HRH2 0.0129
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0129
790 DNA polymerase subunit alpha B POLA2 0.0129
1507 Cytochrome c CYCS 0.0128
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0128
338 DNA polymerase UL30 0.0128
379 DNA polymerase UL54 0.0128
697 DNA polymerase ORF28 0.0128
2482 DNA polymerase 43 0.0128
4104 DNA polymerase BALF5 0.0128
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0127
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0127
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0127
558 Solute carrier family 12 member 1 SLC12A1 0.0126
232 Corticosteroid-binding globulin SERPINA6 0.0125
251 Alcohol dehydrogenase 1A ADH1A 0.0125
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0124
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0124
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.0124
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.0124
1192 Sulfotransferase 1A1 SULT1A1 0.0124
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.0124
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.0123
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.0123
308 30S ribosomal protein S12 rpsL 0.0122
6704 30S ribosomal protein S12 rpsL 0.0122
1517 Beta-3 adrenergic receptor ADRB3 0.0122
620 Bifunctional dihydrofolate reductase-thymidylate synthase Not Available 0.0122
605 Fumarate reductase flavoprotein subunit frdA 0.0121
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0121
3673 Fumarate reductase flavoprotein subunit fccA 0.0121
4912 Fumarate reductase flavoprotein subunit ifcA 0.0121
6549 Fumarate reductase flavoprotein subunit frdA 0.0121
614 Progesterone receptor PGR 0.012
921 Glutamate receptor 2 GRIA2 0.0119
869 Estrogen receptor beta ESR2 0.0118
444 Alcohol dehydrogenase 1B ADH1B 0.0118
163 D(1B) dopamine receptor DRD5 0.0118
183 Vascular endothelial growth factor A VEGFA 0.0117
48 Pyridoxal kinase PDXK 0.0116
3810 Catechol O-methyltransferase COMT 0.0116
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0115
4122 Histone deacetylase 2 HDAC2 0.0115
474 Acetylcholinesterase ACHE 0.0113
2449 Tubulin alpha-3 chain TUBA1A 0.0113
4199 Sphingosine 1-phosphate receptor Edg-8 S1PR5 0.0113
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0113
2499 Tubulin beta-2C chain TUBB2C 0.0113
504 Mast/stem cell growth factor receptor KIT 0.0112
528 5-hydroxytryptamine 1E receptor HTR1E 0.0112
2230 Catalase CAT 0.0112
3249 Catalase katA 0.0112
3625 Catalase katA 0.0112
4539 Catalase katA 0.0112
4941 Catalase katB 0.0112
106 Cannabinoid receptor 2 CNR2 0.0112
3917 Methylenetetrahydrofolate reductase MTHFR 0.0112
1244 Low-density lipoprotein receptor-related protein 2 LRP2 0.0111
4790 Glycosyltransferase GtfA gtfA 0.011
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0109
645 Penicillin-binding protein 1A mrcA 0.0107
5805 Penicillin-binding protein 1A ponA 0.0107
6185 Penicillin-binding protein 1A mrcA 0.0107
6799 Penicillin-binding protein 1A pbpA 0.0107
518 Peroxidase/catalase T katG 0.0106
4116 Dihydropteroate synthetase Not Available 0.0106
1638 Solute carrier family 2, facilitated glucose transporter member 2 SLC2A2 0.0106
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0106
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0106
823 Fibroblast growth factor receptor 2 FGFR2 0.0105
1275 Estrogen sulfotransferase SULT1E1 0.0104
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0103
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0103
818 50S ribosomal protein L10 rplJ 0.0102
365 Dihydrofolate reductase DHFR 0.0102
2381 Dihydrofolate reductase DFR1 0.0102
2833 Dihydrofolate reductase Not Available 0.0102
2931 Dihydrofolate reductase folA 0.0102
3544 Dihydrofolate reductase folA 0.0102
3682 Dihydrofolate reductase folA 0.0102
6642 Dihydrofolate reductase folA 0.0102
6756 Dihydrofolate reductase dfrA 0.0102
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0102
958 Insulin-like growth factor 1 receptor IGF1R 0.0101
161 Tubulin beta chain TUBB 0.01
312 Tubulin beta chain TUB2 0.01
4237 50S ribosomal protein L22 rplV 0.01
140 30S ribosomal protein S9 rpsI 0.01
6719 30S ribosomal protein S9 rpsI 0.01
6725 30S ribosomal protein S9 rpsI 0.01
427 Substance-P receptor TACR1 0.0099
606 Cytochrome P450 27, mitochondrial CYP27A1 0.0099
1256 5-hydroxytryptamine 6 receptor HTR6 0.0098
634 Squalene monooxygenase SQLE 0.0097
7196 Squalene monooxygenase ERG1 0.0097
1714 Mitogen-activated protein kinase 3 MAPK3 0.0097
130 Prostacyclin synthase PTGIS 0.0097
33 Cystine/glutamate transporter SLC7A11 0.0097
563 Thyroid peroxidase TPO 0.0097
6339 Ig kappa chain V-II region RPMI 6410 Not Available 0.0097
1629 Transcription factor AP-1 JUN 0.0096
517 Alcohol dehydrogenase 1C ADH1C 0.0096
49 Endothelin B receptor EDNRB 0.0096
1050 Bile salt sulfotransferase SULT2A1 0.0095
6085 Fatty acid-binding protein, intestinal FABP2 0.0094
511 5-hydroxytryptamine 1F receptor HTR1F 0.0094
5849 cAMP-dependent protein kinase type I-alpha regulatory subunit PRKAR1A 0.0092
228 Beta platelet-derived growth factor receptor PDGFRB 0.0092
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0092
7 Nitric oxide synthase, inducible NOS2 0.0092
1656 CYP2B protein CYP2B 0.0091
6146 High affinity copper uptake protein 1 SLC31A1 0.0091
407 Vascular endothelial growth factor receptor 2 KDR 0.009
578 Endothelin-1 receptor EDNRA 0.009
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.009
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.009
4228 Keratin, type II cytoskeletal 7 KRT7 0.009
6131 Carbonic anhydrase 14 CA14 0.009
24 Thymidylate synthase TMP1 0.009
359 Thymidylate synthase TYMS 0.009
2626 Thymidylate synthase thyA 0.009
2729 Thymidylate synthase thyA 0.009
5352 Thymidylate synthase THYA 0.009
6766 O-GlcNAcase BT_4395 BT_4395 0.0089
2320 Thymidine kinase, cytosolic TK1 0.0089
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0088
4238 50S ribosomal protein L4 rplD 0.0088
5578 50S ribosomal protein L4 rplD 0.0088
6173 50S ribosomal protein L4 rplD 0.0088
6219 50S ribosomal protein L4 rplD 0.0088
131 Synaptic vesicular amine transporter SLC18A2 0.0088
6020 Aldehyde oxidase AOX1 0.0087
3312 Fatty acid-binding protein, brain FABP7 0.0086
4203 Histamine N-methyltransferase HNMT 0.0085
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.0084
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.0084
3806 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A 0.0083
820 Glycine receptor subunit alpha-2 GLRA2 0.0083
4120 NADPH--cytochrome P450 reductase POR 0.0082
2016 Dipeptidase 1 DPEP1 0.0082
185 Vasopressin V1a receptor AVPR1A 0.0082
814 Ryanodine receptor 1 RYR1 0.0081
22 30S ribosomal protein S4 rpsD 0.0081
6714 30S ribosomal protein S4 rpsD 0.0081
565 Extracellular calcium-sensing receptor CASR 0.008
2112 Toll-like receptor 9 TLR9 0.008
322 Vasopressin V2 receptor AVPR2 0.008
26 Vascular endothelial growth factor receptor 3 FLT4 0.0079
173 Toll-like receptor 7 TLR7 0.0079
84 Nuclear receptor 0B1 NR0B1 0.0078
65 Matrix metalloproteinase-9 Not Available 0.0078
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0078
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0077
4311 tRNA TRDMT1 0.0077
4325 tRNA trmD 0.0077
4328 tRNA trmD 0.0077
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0077
543 Penicillin-binding protein 1B mrcB 0.0077
6186 Penicillin-binding protein 1B ponB 0.0077
6822 Penicillin-binding protein 1b pbp1b 0.0077
6844 Penicillin-binding protein 1b pbp1b 0.0077
1648 Elastin ELN 0.0076
904 Glutathione S-transferase P GSTP1 0.0076
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0076
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0076
32 Vascular endothelial growth factor receptor 1 FLT1 0.0076
6149 Solute carrier family 22 member 10 SLC22A10 0.0074
459 Retinoic acid receptor RXR-alpha RXRA 0.0074
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0074
3426 Glutamine synthetase glnA 0.0073
3987 Glutamine synthetase GLUL 0.0073
4148 Serine/threonine-protein kinase mTOR MTOR 0.0073
153 Dopamine beta-hydroxylase DBH 0.0073
5626 Nucleoside diphosphate kinase B NME2 0.0073
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0072
284 DNA-directed RNA polymerase beta chain rpoB 0.0072
5773 DNA-directed RNA polymerase beta chain rpoB 0.0072
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0072
6432 Transporter snf 0.0072
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0072
2236 Casein kinase II subunit alpha CSNK2A1 0.0071
1374 Natriuretic peptides B NPPB 0.007
1827 Gap junction alpha-1 protein GJA1 0.007
1908 Vascular cell adhesion protein 1 VCAM1 0.007
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0069
273 Apoptosis regulator Bcl-2 BCL2 0.0069
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0069
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0069
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0069
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0069
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0069
952 Dipeptidyl peptidase 4 DPP4 0.0069
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0069
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0069
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0067
3937 Fatty-acid amide hydrolase FAAH 0.0067
1636 Trace amine-associated receptor 1 TAAR1 0.0067
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0067
6122 Carbonic anhydrase 3 CA3 0.0066
29 Tubulin beta-1 chain TUBB1 0.0066
527 Prostacyclin receptor PTGIR 0.0066
856 Vitamin D3 receptor VDR 0.0066
4103 Proteasome subunit beta type 2 PSMB2 0.0066
4102 Proteasome subunit beta type 5 PSMB5 0.0066
4101 Proteasome subunit beta type 1 PSMB1 0.0066
750 Voltage-dependent calcium channel gamma-1 subunit CACNG1 0.0065
2981 Phospholipase A2, membrane associated PLA2G2A 0.0065
780 Retinoic acid receptor RXR-gamma RXRG 0.0065
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0065
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0064
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0064
976 Platelet glycoprotein IX GP9 0.0064
1820 Beta-nerve growth factor NGF 0.0064
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0063
6068 Guanylate cyclase soluble subunit alpha-2 GUCY1A2 0.0063
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0063
133 Dihydropterate synthase sulI 0.0063
982 Cocaine- and amphetamine-regulated transcript protein CARTPT 0.0062
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0062
3809 Estrogen-related receptor gamma ESRRG 0.0062
737 Mineralocorticoid receptor NR3C2 0.0062
1618 High affinity nerve growth factor receptor NTRK1 0.0062
2298 Cytochrome P450-cam camC 0.0061
6174 50S ribosomal protein L32 rpmF 0.0061
1558 Transient receptor potential cation channel subfamily V member 1 TRPV1 0.0059
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.0059
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0059
88 Retinoic acid receptor RXR-beta RXRB 0.0059
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.0059
239 Coagulation factor X F10 0.0059
581 Cytochrome P450 2R1 CYP2R1 0.0059
54 Prothrombin F2 0.0059
5294 Nucleoside diphosphate kinase A NME1 0.0058
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0058
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0058
3808 Dihydropteroate synthase 2 folP2 0.0058
3601 Dihydropteroate synthase 1 folP1 0.0058
3807 Dihydropteroate synthase 1 folP1 0.0058
400 Coagulation factor IX F9 0.0057
5461 Coagulation factor IX F9 0.0057
3007 Carbonic anhydrase 12 CA12 0.0057
4205 Carbonic anhydrase 9 CA9 0.0057
1650 Heme carrier protein 1 SLC46A1 0.0057
5934 Cytochrome P450 26A1 CYP26A1 0.0057
703 NADPH azoreductase azr 0.0056
6033 High affinity interleukin-8 receptor A CXCR1 0.0056
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.0055
908 Glutathione S-transferase theta-1 GSTT1 0.0055
6506 Stathmin-4 STMN4 0.0055
466 Solute carrier family 12 member 3 SLC12A3 0.0055
164 Histamine H4 receptor HRH4 0.0054
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0054
5878 Alpha-7 nicotinic cholinergic receptor subunit CHRFAM7A 0.0053
850 Vasopressin V1b receptor AVPR1B 0.0053
390 Adenosine A3 receptor ADORA3 0.0053
5998 Toll-like receptor 8 TLR8 0.0053
2853 14 kDa fatty acid-binding protein Not Available 0.0053
4081 Vitamin K epoxide reductase complex subunit 1-like protein 1 VKORC1L1 0.0052
604 Vitamin K-dependent protein Z PROZ 0.0052
712 Tubulin alpha chain TUB1 0.0052
4217 Telomerase reverse transcriptase TERT 0.0052
822 Aldose reductase AKR1B1 0.0052
259 Microsomal triglyceride transfer protein large subunit MTTP 0.0052
3090 Chitosanase csn 0.0052
4149 Nuclear factor NF-kappa-B p100 subunit NFKB2 0.0052
3823 Cytokine receptor common gamma chain IL2RG 0.0051
438 Taste receptor type 1 member 2 TAS1R2 0.0051
253 Sodium/potassium-transporting ATPase gamma chain FXYD2 0.0051
1196 Complement decay-accelerating factor CD55 0.0051
1039 Histone deacetylase 9 HDAC9 0.005
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.005
4773 Deoxycytidine kinase DCK 0.0049
244 Angiotensin-converting enzyme ACE 0.0049
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0049
6044 Serum paraoxonase/lactonase 3 PON3 0.0049
3957 Adenosine deaminase ADA 0.0049
3404 Exotoxin A eta 0.0049
174 Sigma 1-type opioid receptor SIGMAR1 0.0049
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.0049
4192 DNA topoisomerase 2-beta TOP2B 0.0049
277 Purine nucleoside phosphorylase PNP 0.0049
2870 Purine nucleoside phosphorylase punA 0.0049
2945 Purine nucleoside phosphorylase punA 0.0049
4659 Purine nucleoside phosphorylase TM_1596 0.0049
4825 Purine nucleoside phosphorylase TTHA1435 0.0049
422 Vitamin K-dependent protein C PROC 0.0048
1245 Vitamin K-dependent protein S PROS1 0.0048
6103 Arylamine N-acetyltransferase 1 NAT1 0.0048
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0047
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.0047
621 Periplasmic [Fe] hydrogenase 1 Not Available 0.0047
569 Retinal dehydrogenase 2 ALDH1A2 0.0047
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.0047
1483 Membrane copper amine oxidase AOC3 0.0046
1253 Interferon gamma IFNG 0.0046
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0046
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0046
268 Adenosine A2b receptor ADORA2B 0.0046
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0046
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0046
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0046
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0046
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0046
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0046
3686 Acyl-CoA thioesterase I precursor tesA 0.0045
1992 Vitamin D-binding protein GC 0.0045
992 Protein tyrosine kinase 2 beta PTK2B 0.0045
724 Interleukin-2 receptor alpha chain IL2RA 0.0045
717 Interleukin-2 receptor subunit beta IL2RB 0.0045
2178 Metabotropic glutamate receptor 5 GRM5 0.0045
469 Annexin A1 ANXA1 0.0045
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0044
2808 Chloramphenicol acetyltransferase 3 cat3 0.0044
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0044
6138 Multidrug resistance protein 3 ABCB4 0.0044
611 Retinal dehydrogenase 1 ALDH1A1 0.0044
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0044
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0044
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.0044
3830 Calreticulin CALR 0.0043
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0043
461 Glycine receptor subunit alpha-3 GLRA3 0.0043
2539 Tubulin alpha-1 chain TUBA4A 0.0043
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0043
5698 Riboflavin synthase alpha chain ribE 0.0043
473 L-lactate dehydrogenase A chain LDHA 0.0042
293 Gamma-glutamyl hydrolase GGH 0.0042
714 Glutathione reductase, mitochondrial GSR 0.0042
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0042
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0042
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0042
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0042
1176 Mitogen-activated protein kinase 1 MAPK1 0.0041
115 Penicillin-binding protein 2 mrdA 0.0041
6069 Penicillin-binding protein 2 mrdA 0.0041
6118 Penicillin-binding protein 2 penA 0.0041
6187 Penicillin-binding protein 2 pbpA 0.0041
6686 Penicillin-binding protein 2 pbp2 0.0041
6939 Penicillin-binding protein 2 mrdA 0.0041
7163 Penicillin-binding protein 2 pbpA 0.0041
887 DNA gyrase subunit B gyrB 0.0041
4150 DNA gyrase subunit B gyrB 0.0041
6225 DNA gyrase subunit B gyrB 0.0041
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0041
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0041
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0041
408 Riboflavin kinase RFK 0.0041
319 Opioid receptor, sigma 1 OPRS1 0.0041
2207 Rhodopsin RHO 0.0041
6034 Hydroxyindole O-methyltransferase ASMT 0.0041
6035 Nuclear receptor ROR-beta RORB 0.0041
3997 Cytochrome P450 24A1, mitochondrial CYP24A1 0.0041
6036 Eosinophil peroxidase EPX 0.0041
859 Cellular retinoic acid-binding protein 2 CRABP2 0.004
718 Folate receptor gamma FOLR3 0.004
299 Folate receptor beta FOLR2 0.004
719 Retinoic acid receptor responder protein 1 RARRES1 0.004
2417 Chloramphenicol acetyltransferase cat 0.004
3278 Chloramphenicol acetyltransferase cat 0.004
804 Mitochondrial folate transporter/carrier SLC25A32 0.004
770 Retinoic acid-induced protein 3 GPRC5A 0.004
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.004
6032 PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) fas 0.004
2810 Dr hemagglutinin structural subunit draA 0.004
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.004
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0039
1541 Metalloproteinase mmp20 0.0039
4132 Chloride channel protein ClC-Ka CLCNKA 0.0039
360 Ribonucleoside-diphosphate reductase large subunit RRM1 0.0039
2290 ADP-ribosyl cyclase 2 BST1 0.0039
798 Osteocalcin BGLAP 0.0039
4146 Phosphatidylinositol 3-kinase regulatory subunit gamma PIK3R3 0.0039
4145 Phosphatidylinositol 3-kinase regulatory subunit beta PIK3R2 0.0039
1129 C-C chemokine receptor type 5 CCR5 0.0039
1 Peptidoglycan synthetase ftsI ftsI 0.0038
4155 Peptidoglycan synthetase ftsI ftsI 0.0038
4209 ATP-sensitive inward rectifier potassium channel 8 KCNJ8 0.0038
4164 Potassium voltage-gated channel subfamily KQT member 5 KCNQ5 0.0038
4163 Potassium voltage-gated channel subfamily KQT member 4 KCNQ4 0.0038
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0038
85 Growth hormone receptor GHR 0.0038
5353 Glutamate decarboxylase alpha gadA 0.0037
489 Monocarboxylate transporter 2 SLC16A7 0.0037
1360 Sphingomyelin phosphodiesterase SMPD1 0.0037
208 DNA-directed RNA polymerase beta' chain rpoC 0.0037
5774 DNA-directed RNA polymerase beta' chain rpoC 0.0037
2183 Fatty acid-binding protein, adipocyte FABP4 0.0037
6167 Organic solute transporter subunit beta OSTB 0.0037
6166 Organic solute transporter subunit alpha OSTA 0.0037
276 Sodium- and chloride-dependent GABA transporter 1 SLC6A1 0.0036
2021 Thrombomodulin THBD 0.0036
1867 Major prion protein PRNP 0.0036
1864 RET proto-oncogene RET 0.0036
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0036
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0036
751 Potassium channel subfamily K member 6 KCNK6 0.0036
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0036
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0036
707 72 kDa type IV collagenase MMP2 0.0036
765 Indoleamine 2,3-dioxygenase IDO1 0.0035
369 Coagulation factor VII F7 0.0035
1768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit GNG2 0.0035
117 Sterol O-acyltransferase 1 SOAT1 0.0035
1581 G protein-activated inward rectifier potassium channel 2 KCNJ6 0.0035
1268 Neuropeptide S receptor NPSR1 0.0035
1571 G protein-activated inward rectifier potassium channel 1 KCNJ3 0.0035
889 3-oxoacyl-[acyl-carrier-protein] synthase 1 fabB 0.0035
6860 3-oxoacyl-[acyl-carrier-protein] synthase 1 kasA 0.0035
1025 Aquaporin-1 AQP1 0.0035
939 50S ribosomal protein L3 rplC 0.0035
3126 Poly [ADP-ribose] polymerase 1 PARP1 0.0034
936 Ephrin type-A receptor 2 EPHA2 0.0034
162 Retinoic acid receptor gamma-1 RARG 0.0034
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0034
4226 Uridine phosphorylase 2 UPP2 0.0033
896 Glutathione S-transferase Mu 1 GSTM1 0.0033
596 3-oxo-5-alpha-steroid 4-dehydrogenase 1 SRD5A1 0.0033
1281 Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 0.0033
172 Potassium channel subfamily K member 1 KCNK1 0.0033
332 Beta-lactamase blaZ 0.0033
2478 Beta-lactamase ampC 0.0033
2613 Beta-lactamase ampC 0.0033
2635 Beta-lactamase ampC 0.0033
2700 Beta-lactamase penP 0.0033
5445 Beta-lactamase blaB 0.0033
6019 Beta-lactamase SHV-7 0.0033
6701 Beta-lactamase cphA 0.0033
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0032
4784 Beta-mannosidase manB 0.0032
6695 Beta-mannosidase BT_0458 0.0032
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0032
6163 Copper-transporting ATPase 2 ATP7B 0.0032
6165 Copper-transporting ATPase 1 ATP7A 0.0032
997 Protein kinase C beta type PRKCB 0.0032
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0031
6073 Potassium channel subfamily K member 9 KCNK9 0.0031
6072 Potassium channel subfamily K member 3 KCNK3 0.0031
6207 30S ribosomal protein S14 rpsN 0.0031
6209 30S ribosomal protein S19 rpsS 0.0031
6712 30S ribosomal protein S19 rpsS 0.0031
6726 30S ribosomal protein S19 rpsS 0.0031
1227 Cytochrome b MT-CYB 0.0031
6386 Cytochrome b petB 0.0031
6937 Cytochrome b MT-CYB 0.0031
674 Dihydroorotate dehydrogenase homolog, mitochondrial PFF0160c 0.0031
5300 Antigen peptide transporter 1 TAP1 0.0031
342 P protein [Includes: DNA-directed DNA polymerase P 0.0031
612 P protein [Includes: DNA-directed DNA polymerase P 0.0031
4225 Uridine phosphorylase 1 UPP1 0.0031
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.0031
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.0031
3868 Calcineurin subunit B isoform 2 PPP3R2 0.003
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.003
2578 Tubulin beta-3 chain TUBB3 0.003
165 FL cytokine receptor FLT3 0.003
2285 Streptogramin A acetyltransferase vatD 0.003
741 Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 0.003
1970 Protein kinase C alpha type PRKCA 0.003
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0029
654 Flavin reductase BLVRB 0.0029
3913 Glutamic acid decarboxylase GAD65 0.0029
1569 G1/S-specific cyclin-D1 CCND1 0.0029
2408 Tyrosine-protein kinase SYK SYK 0.0029
413 Amidophosphoribosyltransferase PPAT 0.0029
2515 Amidophosphoribosyltransferase purF 0.0029
3714 Amidophosphoribosyltransferase purF 0.0029
512 DNA-directed RNA polymerase alpha chain rpoA 0.0029
5772 DNA-directed RNA polymerase alpha chain rpoA 0.0029
3688 Branched-chain-amino-acid aminotransferase ilvE 0.0028
4252 Penicillin-binding protein 5 dacA 0.0028
159 Penicillin-binding protein 2B penA 0.0028
6121 Penicillin-binding protein 2B penA 0.0028
330 Spermidine synthase SRM 0.0028
3038 Spermidine synthase speE 0.0028
2998 Sialic acid-binding Ig-like lectin 7 SIGLEC7 0.0028
291 Nitric-oxide synthase, endothelial NOS3 0.0028
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.0028
935 Proto-oncogene tyrosine-protein kinase Yes YES1 0.0028
1063 Signal transducer and activator of transcription 5B STAT5B 0.0028
1200 AMBP protein AMBP 0.0028
3866 Serum amyloid A protein SAA1 0.0028
1932 Apolipoprotein E APOE 0.0028
1144 Hepatocyte growth factor receptor MET 0.0027
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0027
4173 Tyrosine-protein kinase JAK2 JAK2 0.0027
3856 Fibroblast growth factor receptor 3 FGFR3 0.0027
2159 Quinone oxidoreductase CRYZ 0.0027
267 Plasminogen activator inhibitor 1 SERPINE1 0.0027
3849 Insulin-like growth factor-binding protein 7 IGFBP7 0.0027
2009 Protein NOV homolog NOV 0.0027
3847 Neuroendocrine convertase 2 PCSK2 0.0027
1949 Carboxypeptidase E CPE 0.0027
3850 Synaptotagmin-like protein 4 SYTL4 0.0027
3848 Neuroendocrine convertase 1 PCSK1 0.0027
3846 Retinoblastoma-associated protein RB1 0.0027
3685 Catabolite gene activator crp 0.0027
6042 Prostaglandin reductase 2 PTGR2 0.0027
4655 Adenylate cyclase cyaC 0.0027
4759 Adenylate cyclase cyaB2 0.0027
6500 Phospholipase A2 PLA2G1B 0.0026
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0026
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0026
358 Cystathionine beta-synthase CBS 0.0026
1630 Integrin beta-2 ITGB2 0.0026
6100 BDNF/NT-3 growth factors receptor NTRK2 0.0026
78 Acetyl-CoA acetyltransferase, mitochondrial ACAT1 0.0025
509 Thymidine kinase TK 0.0025
570 Thymidine kinase TK 0.0025
2559 Thymidine kinase TK 0.0025
3430 Thymidine kinase tdk 0.0025
3518 Thymidine kinase TK 0.0025
5301 Thymidine kinase tdk 0.0025
5771 Thymidine kinase ORF36 0.0025
7009 Thymidine kinase ORF36 0.0025
5880 Thrombopoietin receptor MPL 0.0025
4787 Envelope glycoprotein gp160 env 0.0025
4820 Envelope glycoprotein gp160 env 0.0025
5727 Envelope glycoprotein gp160 env 0.0025
1792 Tissue-type plasminogen activator PLAT 0.0025
768 FK506-binding protein 1A FKBP1A 0.0025
934 Proto-oncogene tyrosine-protein kinase Fyn FYN 0.0024
735 Alanine aminotransferase 1 GPT 0.0024
3904 Alanine aminotransferase 2 GPT2 0.0024
759 Free fatty acid receptor 1 FFAR1 0.0024
334 S-adenosylmethionine synthetase isoform type-2 MAT2A 0.0024
1818 Long-chain-fatty-acid--CoA ligase 3 ACSL3 0.0024
544 Potassium voltage-gated channel subfamily E member 1 KCNE1 0.0024
6221 Steroid hormone receptor ERR1 ESRRA 0.0024
2300 Lysozyme E 0.0024
3633 Lysozyme R 0.0024
5597 Lysozyme 17 0.0024
5787 Angiopoietin-1 receptor TEK 0.0024
6039 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A PDE11A 0.0024
215 Sodium channel protein type 11 subunit alpha SCN11A 0.0024
471 Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) SLC6A14 0.0024
2297 Genome polyprotein Not Available 0.0024
2322 Genome polyprotein Not Available 0.0024
2694 Genome polyprotein Not Available 0.0024
2719 Genome polyprotein Not Available 0.0024
2860 Genome polyprotein Not Available 0.0024
2928 Genome polyprotein Not Available 0.0024
3160 Genome polyprotein Not Available 0.0024
3260 Genome polyprotein Not Available 0.0024
4783 Genome polyprotein Not Available 0.0024
5726 Genome polyprotein Not Available 0.0024
5779 Genome polyprotein Not Available 0.0024
5867 Genome polyprotein Not Available 0.0024
6253 Genome polyprotein Not Available 0.0024
6301 Genome polyprotein Not Available 0.0024
6380 Genome polyprotein Not Available 0.0024
6381 Genome polyprotein Not Available 0.0024
6437 Genome polyprotein Not Available 0.0024
6520 Genome polyprotein Not Available 0.0024
6521 Genome polyprotein Not Available 0.0024
6652 Genome polyprotein Not Available 0.0024
6734 Genome polyprotein Not Available 0.0024
6735 Genome polyprotein Not Available 0.0024
6736 Genome polyprotein Not Available 0.0024
6737 Genome polyprotein Not Available 0.0024
6738 Genome polyprotein Not Available 0.0024
6739 Genome polyprotein Not Available 0.0024
6744 Genome polyprotein Not Available 0.0024
6748 Genome polyprotein Not Available 0.0024
6894 Genome polyprotein Not Available 0.0024
6898 Genome polyprotein Not Available 0.0024
6070 Nischarin NISCH 0.0024
233 Potassium channel subfamily K member 2 KCNK2 0.0024
5852 Type-2 angiotensin II receptor AGTR2 0.0024
642 3-oxo-5-alpha-steroid 4-dehydrogenase 2 SRD5A2 0.0023
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0023
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0023
3086 Plasmepsin-2 Not Available 0.0023
550 Amiloride-sensitive sodium channel subunit delta SCNN1D 0.0023
27 Amiloride-sensitive sodium channel subunit beta SCNN1B 0.0023
552 Amiloride-sensitive sodium channel subunit gamma SCNN1G 0.0023
213 Amiloride-sensitive sodium channel subunit alpha SCNN1A 0.0023
1830 5'-nucleotidase NT5E 0.0023
2249 Aspartate aminotransferase aspC 0.0023
2671 Aspartate aminotransferase aspC 0.0023
5490 Aspartate aminotransferase Not Available 0.0023
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.0023
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0023
1341 Histamine H3 receptor HRH3 0.0023
4760 Mll3241 protein mll3241 0.0023
6218 Pannexin-1 PANX1 0.0022
484 Tyrosine-protein kinase ABL2 ABL2 0.0022
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0022
476 RAC-alpha serine/threonine-protein kinase AKT1 0.0022
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0022
990 Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 0.0022
113 S-adenosylmethionine decarboxylase proenzyme AMD1 0.0022
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0022
3480 Mannan endo-1,4-beta-mannosidase manA 0.0022
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0022
411 Glycine N-methyltransferase GNMT 0.0022
2155 Insulin-degrading enzyme IDE 0.0022
2232 Interleukin-5 IL5 0.0022
298 Renin REN 0.0021
1593 Mucin-2 MUC2 0.0021
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0021
3437 Eosinophil lysophospholipase CLC 0.0021
2091 Endoplasmin HSP90B1 0.0021
1053 BC269730_2 FADS1 0.0021
1395 Sodium/calcium exchanger 1 SLC8A1 0.0021
1198 Serum paraoxonase/arylesterase 1 PON1 0.0021
6223 Penicillin-binding protein 1C pbpC 0.0021
1852 Microtubule-associated protein 2 MAP2 0.0021
63 Malate dehydrogenase mdh 0.0021
2329 Malate dehydrogenase mdh 0.0021
3445 Malate dehydrogenase mdh 0.0021
4420 Malate dehydrogenase mdh 0.0021
4438 Malate dehydrogenase mdh 0.0021
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0021
828 Phenylalanine-4-hydroxylase PAH 0.0021
3109 Phenylalanine-4-hydroxylase phhA 0.0021
132 ATP-binding cassette sub-family A member 1 ABCA1 0.002
1313 Lactoylglutathione lyase GLO1 0.002
672 Prostaglandin F2-alpha receptor PTGFR 0.002
3611 Cytidine deaminase cdd 0.002
3707 Cytidine deaminase cdd 0.002
4211 Cytidine deaminase CDA 0.002
572 Integrin alpha-L ITGAL 0.002
1243 Cathepsin D CTSD 0.0019
867 Penicillin-binding protein 3 pbpC 0.0019
6119 Penicillin-binding protein 3 pbp3 0.0019
7154 Penicillin-binding protein 3 pbp3 0.0019
7157 Penicillin-binding protein 3 LMHCC_2184 0.0019
7162 Penicillin-binding protein 3 pbpB 0.0019
7172 Penicillin-binding protein 3 pbp3 0.0019
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0019
1654 Interleukin-1 beta IL1B 0.0019
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0018
893 [Citrate [pro-3S]-lyase] ligase citC 0.0018
845 Pyruvate dehydrogenase [cytochrome] poxB 0.0018
1968 ATP-sensitive inward rectifier potassium channel 12 KCNJ12 0.0018
327 Glutathione reductase gor 0.0018
5110 Glutathione reductase GR2 0.0018
683 Potassium transporter GK0582 0.0018
748 5'-AMP-activated protein kinase catalytic subunit alpha-1 PRKAA1 0.0018
53 Solute carrier family 12 member 5 SLC12A5 0.0018
663 Solute carrier family 12 member 4 SLC12A4 0.0018
1123 Eosinophil cationic protein RNASE3 0.0018
67 Prolyl 4-hydroxylase subunit alpha-1 P4HA1 0.0017
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0017
3221 Cytochrome c4 cc4 0.0017
310 Solute carrier family 12 member 2 SLC12A2 0.0017
144 Hemoglobin subunit alpha HBA1 0.0016
102 DNA topoisomerase I, mitochondrial TOP1MT 0.0016
3233 Bile acid receptor NR1H4 0.0015
494 Caspase-1 CASP1 0.0015
4785 Ig gamma-1 chain C region IGHG1 0.0015
6048 Troponin C, skeletal muscle TNNC2 0.0015
3844 HLA class II histocompatibility antigen, DQ(6) alpha chain HLA-DQA2 0.0015
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0015
1405 Thiopurine S-methyltransferase TPMT 0.0015
5798 Mitogen-activated protein kinase 11 MAPK11 0.0015
6824 Tyrosine-protein kinase Lyn LYN 0.0014
3760 Penicillin-binding protein 5 precursor dacA 0.0014
1262 Corticotropin-lipotropin POMC 0.0014
6859 Protein S100-A4 S100A4 0.0014
6002 Prostaglandin E2 receptor EP4 subtype PTGER4 0.0013
677 Choline-phosphate cytidylyltransferase A PCYT1A 0.0013
1353 DNA topoisomerase 1 TOP1 0.0013
3552 DNA topoisomerase 1 topA 0.0013
6184 D-alanyl-D-alanine carboxypeptidase dacC dacC 0.0013
561 Retinol-binding protein II, cellular RBP2 0.0013
35 Dehydrogenase/reductase SDR family member 4 DHRS4 0.0013
4073 Retinol dehydrogenase 11 RDH11 0.0013
4074 Retinol dehydrogenase 14 RDH14 0.0013
1097 Lecithin retinol acyltransferase LRAT 0.0013
589 Retinoid-binding protein 7 RBP7 0.0013
753 Retinol-binding protein III, cellular RBP5 0.0013
4071 Short-chain dehydrogenase/reductase 3 DHRS3 0.0013
4075 Photoreceptor outer segment all-trans retinol dehydrogenase RDH8 0.0013
863 Cellular retinaldehyde-binding protein RLBP1 0.0013
800 Retinol dehydrogenase 12 RDH12 0.0013
282 Interphotoreceptor retinoid-binding protein RBP3 0.0013
651 Retinol dehydrogenase 13 RDH13 0.0013
4072 All-trans-retinol 13,14-reductase RETSAT 0.0013
6211 Tubulin epsilon chain TUBE1 0.0013
6212 Tubulin gamma-1 chain TUBG1 0.0013
6210 Tubulin delta chain TUBD1 0.0013
2077 Caspase-3 CASP3 0.0013
4131 Prostaglandin E2 receptor, EP3 subtype PTGER3 0.0013
860 Nicotinamide N-methyltransferase NNMT 0.0013
699 Nicotinic acid receptor 1 GPR109A 0.0013
928 Nicotinic acid receptor 2 GPR109B 0.0013
583 Nicotinate-nucleotide pyrophosphorylase [carboxylating] QPRT 0.0013
2442 Nicotinate-nucleotide pyrophosphorylase [carboxylating] nadC 0.0013
2459 Nicotinate-nucleotide pyrophosphorylase [carboxylating] nadC 0.0013
6116 Gastric triacylglycerol lipase LIPF 0.0012
406 Prostaglandin E2 receptor, EP2 subtype PTGER2 0.0012
819 Penicillin-binding protein 4 dacB 0.0012
760 Fibroblast growth factor 1 FGF1 0.0012
2107 Microtubule-associated protein 1A MAP1A 0.0012
5924 Microtubule-associated protein 4 MAP4 0.0012
5923 Microtubule-associated protein tau MAPT 0.0012
1295 Fatty acid synthase FASN 0.0012
702 UMP-CMP kinase CMPK1 0.0012
331 Retinol-binding protein I, cellular RBP1 0.0012
627 11-cis retinol dehydrogenase RDH5 0.0011
640 Aldehyde dehydrogenase 1A3 ALDH1A3 0.0011
2461 D-alanyl-D-alanine carboxypeptidase Not Available 0.0011
5756 D-alanyl-D-alanine carboxypeptidase dac 0.0011
754 Pancreatic triacylglycerol lipase PNLIP 0.0011
4692 A/G-specific adenine glycosylase mutY 0.0011
4948 Cytochrome c-553 Not Available 0.0011
4923 Cytochrome c3 DvMF_2499 0.0011
4945 Cytochrome c3 Not Available 0.0011
4949 Cytochrome c3 DVU_3171 0.0011
4968 Cytochrome c3 cytc3 0.0011
4997 Cytochrome c3 SO_2727 0.0011
5219 Cytochrome c3 cyd 0.0011
4902 Nine-heme cytochrome c Ddes_2038 0.0011
3189 High-molecular-weight cytochrome c hmcA 0.0011
1810 Protein S100-A1 S100A1 0.001
6097 Protein S100-A2 S100A2 0.001
3238 Multidrug resistance protein mexA mexA 0.001
3709 Glycerol uptake facilitator protein glpF 0.001
3116 Bacterioferritin bfr 0.001
4906 Bacterioferritin bfr 0.001
4965 Bacterioferritin bfr 0.001
5489 Ribonucleoside-diphosphate reductase 1 subunit beta nrdB 0.001
3173 Enolase eno 0.001
3336 C4-dicarboxylate transport transcriptional regulatory protein dctD dctD 0.001
3393 TGF-beta receptor type-2 TGFBR2 0.001
493 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 0.001
2216 Fibroblast growth factor receptor 4 FGFR4 0.001
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.001
345 Plasma retinol-binding protein RBP4 0.001
4041 Microsomal glutathione S-transferase 2 MGST2 0.001
2802 Endoglucanase G celCCG 0.001
2268 Cholesterol oxidase choB 0.0009
2822 Cholesterol oxidase choA 0.0009
229 Retinoic acid receptor beta RARB 0.0009
1064 DNA (cytosine-5)-methyltransferase 1 DNMT1 0.0009
6105 3-oxo-5-beta-steroid 4-dehydrogenase AKR1D1 0.0009
4386 Hemoglobin-like protein HbN glbN 0.0009
730 Retinoic acid receptor alpha RARA 0.0009
1048 Protein S100-A13 S100A13 0.0009
2226 Protein S100-A12 S100A12 0.0009
2852 DNA mismatch repair protein mutL mutL 0.0009
1759 85 kDa calcium-independent phospholipase A2 PLA2G6 0.0009
1770 Phospholipase C PLCL1 0.0009
2841 Phospholipase C plc 0.0009
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0009
2283 Steroid Delta-isomerase ksi 0.0009
2920 Steroid Delta-isomerase ksi 0.0009
3191 Histidinol dehydrogenase hisD 0.0009
76 Nitric-oxide synthase, brain NOS1 0.0009
6169 ATP-binding cassette sub-family A member 5 ABCA5 0.0009
2132 Protein S100-B S100B 0.0009
740 Argininosuccinate synthase ASS1 0.0009
865 Argininosuccinate synthase ASS1 0.0009
2680 Argininosuccinate synthase argG 0.0009
3194 Argininosuccinate synthase argG 0.0009
1184 Interferon beta IFNB1 0.0008
5818 Folate receptor alpha FOLR1 0.0008
2325 Sulfotransferase family cytosolic 2B member 1 SULT2B1 0.0008
6459 Glycodelin PAEP 0.0008
3587 Gastrotropin FABP6 0.0008
4031 Glutathione S-transferase A1 GSTA1 0.0008
500 Monocarboxylate transporter 4 SLC16A3 0.0008
1649 Small inducible cytokine A2 CCL2 0.0008
6893 Calcium/calmodulin-dependent protein kinase type II gamma chain CAMK2G 0.0007
866 Large neutral amino acids transporter small subunit 2 SLC7A8 0.0007
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0007
6316 ADP-ribosylation factor 1 ARF1 0.0007
6228 Nuclear receptor coactivator 1 NCOA1 0.0007
6134 Sodium channel subunit beta-3 SCN3B 0.0007
6133 Sodium channel subunit beta-2 SCN2B 0.0007
6135 Sodium channel subunit beta-4 SCN4B 0.0007
6241 Nuclear receptor coactivator 2 NCOA2 0.0007
6132 Sodium channel subunit beta-1 SCN1B 0.0007
6129 Carbonic anhydrase-related protein 11 CA11 0.0007
6127 Carbonic anhydrase-related protein CA8 0.0007
6128 Carbonic anhydrase-related protein 10 CA10 0.0007
3876 Aromatic-L-amino-acid decarboxylase DDC 0.0007
226 Gonadotropin-releasing hormone receptor GNRHR 0.0007
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0007
4666 Fucose-binding lectin PA-IIL lecB 0.0007
2372 Bifunctional tail protein 9 0.0007
125 DNA polymerase beta POLB 0.0007
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0007
2599 Tyrosine-protein kinase HCK HCK 0.0007
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0006
4878 Glycoprotein hormones alpha chain CGA 0.0006
1052 Cytotoxic T-lymphocyte protein 4 CTLA4 0.0006
1072 Granzyme B GZMB 0.0006
4871 Endo-beta-N-acetylglucosaminidase F3 endOF3 0.0006
4880 Membrane cofactor protein CD46 0.0006
4889 Ig epsilon chain C region IGHE 0.0006
4877 Beta-mannanase man 0.0006
1563 Platelet glycoprotein Ib alpha chain GP1BA 0.0006
4850 Beta-2-glycoprotein 1 APOH 0.0006
4856 CD209 antigen CD209 0.0006
4189 Alpha-galactosidase A GLA 0.0006
4869 Major capsid protein A430L 0.0006
757 Fusion glycoprotein F0 F 0.0006
4875 Fusion glycoprotein F0 F 0.0006
4852 Reticulon-4 receptor RTN4R 0.0006
4845 ADAM 33 ADAM33 0.0006
1354 Beta-glucuronidase GUSB 0.0006
4882 Dipeptidyl aminopeptidase-like protein 6 DPP6 0.0006
4721 Beta-1,4-mannanase manA 0.0006
3352 Structural polyprotein Not Available 0.0006
3628 Structural polyprotein Not Available 0.0006
4892 Structural polyprotein Not Available 0.0006
4934 Cytochrome c-551 nirM 0.0006
5218 Cytochrome c-551 nirM 0.0006
4916 Cyanoglobin glbN 0.0006
4943 Cytochrome c6 petJ 0.0006
4954 Soluble cytochrome b558 Not Available 0.0006
4905 Cytochrome c2 Not Available 0.0006
4939 Cytochrome c2 cycA 0.0006
4964 Cytochrome c2 cycA 0.0006
4979 Cytochrome c2 cycA 0.0006
6673 Cytochrome c2 cycA 0.0006
4915 Cytochrome c-550 psbV 0.0006
4959 Cytochrome c-550 psbV 0.0006
5216 Cytochrome c-550 psbV 0.0006
4925 Cytochrome c-type protein SHP shp 0.0006
4947 Bacterial hemoglobin vhb 0.0006
4994 Hemoglobin-like protein HbO glbO 0.0006
4984 Neuroglobin NGB 0.0006
4975 Cytochrome c-556 RPA3973 0.0006
4942 Diheme cytochrome c napB napB 0.0006
4936 Cytochrome c2 iso-2 Not Available 0.0006
4998 Hemoglobin-like protein yjbI yjbI 0.0006
4981 Iron-starvation protein PigA pigA 0.0006
4909 CooA protein cooA 0.0006
5000 HemO hemO 0.0006
4961 Hemophore HasA hasA 0.0006
4907 Cytochrome c-L moxG 0.0006
6865 Cytochrome c-L moxG 0.0006
4910 Cytoglobin CYGB 0.0006
4976 Apocytochrome f petA 0.0006
6407 Apocytochrome f petA 0.0006
644 Heme oxygenase 2 HMOX2 0.0006
4982 Heme oxygenase 2 pbsA2 0.0006
4971 Nonaheme cytochrome c hmcA 0.0006
4904 Cytochrome c family protein GSU1996 0.0006
4935 Cytochrome c-554 cycA1 0.0006
4926 Heme-based aerotactic transducer hemAT hemAT 0.0006
4989 Cytochrome c551 peroxidase ccp 0.0006
5222 Cytochrome c551 peroxidase ccpA 0.0006
4937 Cytochrome oxidase subunit II rcoxA 0.0006
4764 Cytochrome P450 165C4 CYP165C4 0.0006
4931 Cytochrome P450 167A1 CYP167A1 0.0006
4960 Putative cytochrome P450-family protein SCO7417 0.0006
4999 Cytochrome P450 165B3 CYP165B3 0.0006
4972 P450cin cinA 0.0006
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0006
4903 Methyl-accepting chemotaxis protein Tar4 0.0006
4993 Hydroxylamine oxidoreductase hao1 0.0006
4952 Catalase/peroxidase katA 0.0006
4922 Cytochrome c, putative SO_4144 0.0006
3093 Catalase HPII katE 0.0006
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0006
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.0006
6130 Carbonic anhydrase 13 CA13 0.0006
890 Niemann-Pick C1-like protein 1 NPC1L1 0.0006
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0006
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0006
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0006
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.0006
6168 Solute carrier family 22 member 16 SLC22A16 0.0006
1291 cAMP response element-binding protein CREB1 0.0006
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0006
4193 Atrial natriuretic peptide clearance receptor NPR3 0.0006
793 T-cell surface antigen CD2 CD2 0.0006
4861 Interleukin-6 receptor alpha chain IL6R 0.0006
119 Carcinoembryonic antigen-related cell adhesion molecule 1 CEACAM1 0.0006
3837 Cytokine receptor common beta chain CSF2RB 0.0006
1525 Heparin-binding growth factor 2 FGF2 0.0006
5221 Cytochrome c3, 13 kDa Not Available 0.0006
3152 Cytochrome c'' cycA 0.0006
5220 Split-Soret cytochrome c Ddes_2150 0.0006
3700 Cytochrome c-552 precursor nrfA 0.0006
2430 Chondroitinase B cslB 0.0005
4210 Toll-like receptor 4 TLR4 0.0005
1760 Aminopeptidase N ANPEP 0.0005
6843 Aminopeptidase N pepN 0.0005
6151 Monocarboxylate transporter 10 SLC16A10 0.0005
1379 Interleukin-12 subunit beta IL12B 0.0005
4890 Hemagglutinin HA 0.0005
6566 Hemagglutinin Not Available 0.0005
3127 Nitrite reductase nirS 0.0005
3284 Nitrite reductase nirS 0.0005
4857 Zinc-alpha-2-glycoprotein AZGP1 0.0005
4920 Peroxidase/catalase katG 0.0005
6858 Inactive carboxylesterase 4 CES1P1 0.0005
2119 Cytochrome b5 CYB5A 0.0005
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0005
4990 PpcA ppcA 0.0005
4037 Hypothetical protein GPX1 0.0005
4297 Hypothetical protein SP_1951 0.0005
4521 Hypothetical protein BC_2969 0.0005
4540 Hypothetical protein TM_1070 0.0005
4555 Hypothetical protein MT1739 0.0005
4569 Hypothetical protein mshD 0.0005
4578 Hypothetical protein PA3270 0.0005
4747 Hypothetical protein PA3967 0.0005
5177 Hypothetical protein TM_0096 0.0005
5194 Hypothetical protein PA1204 0.0005
5240 Hypothetical protein Rv2991 0.0005
5370 Hypothetical protein TM_1158 0.0005
5710 Hypothetical protein Tb927.5.1360 0.0005
4988 Sulfite oxidase, mitochondrial SUOX 0.0005
3570 Cytochrome P450 152A1 cypC 0.0005
3375 Acidic cytochrome c3 Not Available 0.0005
2915 Sensor protein fixL fixL 0.0005
4944 Sensor protein fixL fixL 0.0005
4289 Cytochrome P450 TT_P0059 0.0005
6262 Cytochrome P450 staP 0.0005
4992 Cytochrome c peroxidase Not Available 0.0005
4385 Cytochrome c' Not Available 0.0005
4967 Cytochrome c' cycA 0.0005
5038 Cytochrome c' Not Available 0.0005
5223 Cytochrome c' cycP 0.0005
4813 Heme oxygenase hmuO 0.0005
5769 Heme oxygenase Not Available 0.0005
6120 Cation-independent mannose-6-phosphate receptor IGF2R 0.0005
18 High affinity immunoglobulin epsilon receptor subunit alpha FCER1A 0.0005
554 Low-density lipoprotein receptor LDLR 0.0004
852 Heparin cofactor 2 SERPIND1 0.0004
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0004
3405 Quinohaemoprotein ethanol dehydrogenase type-1 qheDH 0.0004
1859 Prostatic acid phosphatase ACPP 0.0004
595 Fibrinogen alpha chain FGA 0.0004
3140 Hemagglutinin-neuraminidase HN 0.0004
3609 Hemagglutinin-neuraminidase HN 0.0004
3444 Cyanovirin-N Not Available 0.0004
3258 Mannosyl-oligosaccharide alpha-1,2-mannosidase MSDC 0.0004
3670 Soluble cytochrome b562 precursor cybC 0.0004
3411 Cytochrome P450 121 cyp121 0.0004
2617 Nitric oxide synthase oxygenase nos 0.0004
2701 Nitric oxide synthase oxygenase nos 0.0004
3291 Cytochrome c-552 cycA 0.0004
4927 Cytochrome c-552 nrfA 0.0004
4938 Cytochrome c-552 cycA 0.0004
4953 Cytochrome c-552 nrfA 0.0004
5217 Cytochrome c-552 cycM 0.0004
3102 Flavohemoprotein hmp 0.0004
4969 Flavohemoprotein hmp 0.0004
4509 Acetoin(diacetyl) reductase budC 0.0004
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0004
2972 6-deoxyerythronolide B hydroxylase eryF 0.0004
594 Thyroxine-binding globulin SERPINA7 0.0004
3689 Endoglucanase A celA 0.0004
3814 Complement C1r subcomponent C1R 0.0004
3009 Beta-glucanase Not Available 0.0004
5411 Slt-IIvB stxB2e 0.0004
5565 Inorganic polyphosphate/ATP-glucomannokinase ppgmk 0.0004
5563 Galectin-2 LGALS2 0.0004
1875 Pulmonary surfactant-associated protein D SFTPD 0.0004
5569 Endo-1,4-beta glucanase EngF engF 0.0004
5046 Ecotin eco 0.0004
3793 Aspartate ammonia-lyase aspA 0.0004
5554 D-galactose-binding periplasmic protein mglB 0.0004
3741 D-galactose-binding periplasmic protein precursor mglB 0.0004
5568 Endoglucanase C307 celC307 0.0004
5553 Endoglucanase E1 Acel_0614 0.0004
5562 Hexokinase Not Available 0.0004
3744 Endoglucanase SS precursor celS 0.0004
5570 Endoglucanase E-4 celD 0.0004
5559 Neopullulanase nplT 0.0004
4670 Cellulase B celB 0.0004
4668 Laminarinase TM_0024 0.0004
4667 BH0236 protein BH0236 0.0004
4671 Endoglucanase C cenC 0.0004
64 Neuraminidase NA 0.0004
641 Neuraminidase NA 0.0004
2676 Neuraminidase NA 0.0004
3026 Neuraminidase NA 0.0004
3519 Neuraminidase NA 0.0004
6007 Neuraminidase NA 0.0004
2577 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase MAN1B1 0.0004
4608 Putative cytochrome P450 SCO1207 0.0003
4963 Putative cytochrome P450 SCO2884 0.0003
6254 Putative cytochrome P450 SCO6998 0.0003
1439 Lactotransferrin LTF 0.0003
309 Antithrombin-III SERPINC1 0.0003
758 Thyroid hormone receptor alpha THRA 0.0003
1782 Neutrophil gelatinase-associated lipocalin LCN2 0.0003
2240 Cell division protein kinase 2 CDK2 0.0003
5176 YtnJ moxC 0.0003
5416 Coat protein VP1 Not Available 0.0003
2705 Dimethyl sulfoxide reductase dmsA 0.0003
199 Monocarboxylate transporter 8 SLC16A2 0.0003
5247 Endo-1,4-beta-xylanase Not Available 0.0003
5248 Endo-1,4-beta-xylanase xlnA 0.0003
5250 Endo-1,4-beta-xylanase xyl 0.0003
693 Hemoglobin subunit beta HBB 0.0003
4669 Endo-1,4-beta-xylanase A xynA 0.0003
4715 Endo-1,4-beta-xylanase A xlnA 0.0003
5560 Endo-1,4-beta-xylanase A xynA 0.0003
1503 Galectin-7 LGALS7 0.0003
5498 Maltoporin lamB 0.0003
5561 Maltoporin lamB 0.0003
5056 Maltooligosyltrehalose trehalohydrolase, putative treZ 0.0003
3525 ADP-ribose pyrophosphatase, mitochondrial NUDT9 0.0003
4622 Amylase Not Available 0.0003
2728 Glucan 1,4-alpha-maltotetraohydrolase amyP 0.0003
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0003
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0003
6307 Ig gamma-2 chain C region IGHG2 0.0003
2826 Glucose--fructose oxidoreductase gfo 0.0003
1881 Hexokinase-1 HK1 0.0003
2581 Chondroitinase AC cslA 0.0003
6847 Lactase-phlorizin hydrolase LCT 0.0003
346 Thyroid hormone receptor beta-1 THRB 0.0003
6268 Hydroxyacid oxidase 1 HAO1 0.0003
2324 Botulinum neurotoxin type B botB 0.0003
3153 Quinoprotein glucose dehydrogenase-B gdhB 0.0003
3747 Cellulase B precursor celB 0.0003
3547 Enterotoxin type B entB 0.0003
2856 Glucosamine-6-phosphate isomerase GNPDA1 0.0003
810 Heme oxygenase 1 HMOX1 0.0003
3391 Heme oxygenase 1 pbsA1 0.0003
2564 Glucan 1,4-alpha-maltohexaosidase Not Available 0.0003
4819 Hydrolase Not Available 0.0003
5249 Hydrolase Not Available 0.0003
5436 Hydrolase Not Available 0.0003
2531 Alpha-amylase amyE 0.0003
2948 Alpha-amylase amy 0.0003
3169 Alpha-amylase Not Available 0.0003
2541 Neopullulanase 1 tvaI 0.0003
4811 Amylosucrase ams 0.0003
3091 Maltodextrin phosphorylase malP 0.0003
2606 Neopullulanase 2 tvaII 0.0003
3225 Shiga toxin B-chain stxB 0.0003
3365 Beta-amylase spoII 0.0003
4830 Aldose 1-epimerase galM 0.0003
6614 Lactase-like protein LCTL 0.0003
1675 Glucokinase GCK 0.0003
4662 Glucokinase glk 0.0003
3030 Salivary alpha-amylase AMY1A 0.0003
2293 Cyclomaltodextrin glucanotransferase Not Available 0.0003
2508 Cyclomaltodextrin glucanotransferase cgt 0.0003
2523 Cyclomaltodextrin glucanotransferase cgt 0.0003
3207 Cyclomaltodextrin glucanotransferase amyA 0.0003
4272 POSSIBLE CELLULASE CELA1 celA1 0.0003
2570 Tetanus toxin tetX 0.0002
2448 Exoglucanase/xylanase [Includes: Exoglucanase cex 0.0002
3668 Maltose-binding periplasmic protein precursor malE 0.0002
2440 Endoglucanase F celCCF 0.0002
2245 Xylose isomerase xylA 0.0002
2253 Xylose isomerase xylA 0.0002
2260 Xylose isomerase xylA 0.0002
2431 Xylose isomerase xylA 0.0002
2252 Endoglucanase 5A cel5A 0.0002
10 Glycogen phosphorylase, liver form PYGL 0.0002
2723 Cholera enterotoxin subunit B ctxB 0.0002
4513 Pancreatic alpha-amylase AMY2A 0.0002
2427 Ferrichrome-iron receptor fhuA 0.0002
1152 Glycogen phosphorylase, muscle form PYGM 0.0002
↑