Partner ID 334
Name S-adenosylmethionine synthetase isoform type-2
Synonyms 1013
Gene name MAT2A
General function Coenzyme transport and metabolism
Specific function Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Gene sequence + ...

ATGAACGGACAGCTCAACGGCTTCCACGAGGCGTTCATCGAGGAGGGCACATTCCTTTTCACCTCAGAGTCGGTCGGGGAAGGCCACCCAGATAAGATTTGTGACCAAATCAGTGATGCTGTCCTTGATGCCCACCTTCAGCAGGATCCTGATGCCAAAGTAGCTTGTGAAACTGTTGCTAAAACTGGAATGATCCTTCTTGCTGGGGAAATTACATCCAGAGCTGCTGTTGACTACCAGAAAGTGGTTCGTGAAGCTGTTAAACACATTGGATATGATGATTCTTCCAAAGGTTTTGACTACAAGACTTGTAACGTGCTGGTAGCCTTGGAGCAACAGTCACCAGATATTGCTCAAGGTGTTCATCTTGACAGAAATGAAGAAGACATTGGTGCTGGAGACCAGGGCTTAATGTTTGGCTATGCCACTGATGAAACTGAGGAGTGTATGCCTTTAACCATTGTCTTGGCACACAAGCTAAATGCCAAACTGGCAGAACTACGCCGTAATGGCACTTTGCCTTGGTTACGCCCTGATTCTAAAACTCAAGTTACTGTGCAGTATATGCAGGATCGAGGTGCTGTGCTTCCCATCAGAGTCCACACAATTGTTATATCTGTTCAGCATGATGAAGAGGTTTGTCTTGATGAAATGAGGGATGCCCTAAAGGAGAAAGTCATCAAAGCAGTTGTGCCTGCGAAATACCTTGATGAGGATACAATCTACCACCTACAGCCAAGTGGCAGATTTGTTATTGGTGGGCCTCAGGGTGATGCTGGTTTGACTGGACGGAAAATCATTGTGGACACTTATGGCGGTTGGGGTGCTCATGGAGGAGGTGCCTTTTCAGGAAAGGATTATACCAAGGTCGACCGTTCAGCTGCTTATGCTGCTCGTTGGGTGGCAAAATCCCTTGTTAAAGGAGGTCTGTGCCGGAGGGTTCTTGTTCAGGTCTCTTATGCTATTGGAGTTTCTCATCCATTATCTATCTCCATTTTCCATTATGGTACCTCTCAGAAGAGTGAGAGAGAGCTATTAGAGATTGTGAAGAAGAATTTCGATCTCCGCCCTGGGGTCATTGTCAGGGATCTGGATCTGAAGAAGCCAATTTATCAGAGGACTGCAGCCTATGGCCACTTTGGTAGGGACAGCTTCCCATGGGAAGTGCCCAAAAAGCTTAAATATTGA

Protein sequence + ...

MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY

GO Classification
function
transferase activity
ATP binding
transferase activity, transferring alkyl or aryl (other than methyl) groups
methionine adenosyltransferase activity
binding
nucleotide binding
catalytic activity
purine nucleotide binding
adenyl nucleotide binding
process
one-carbon compound metabolism
physiological process
metabolism
cellular metabolism
See more information at   →   www.drugbank.ca
Id Name
DB00118 S-Adenosylmethionine
Id Name
DB00134 L-Methionine
Id Name
DB00041 Aldesleukin
DB00082 Pegvisomant
DB00109 Enfuvirtide
DB00114 Pyridoxal Phosphate
DB00115 Cyanocobalamin
DB00116 Tetrahydrofolic acid
DB00117 L-Histidine
DB00118 S-Adenosylmethionine
DB00119 Pyruvic acid
DB00120 L-Phenylalanine
DB00123 L-Lysine
DB00125 L-Arginine
DB00128 L-Aspartic Acid
DB00130 L-Glutamine
DB00133 L-Serine
DB00134 L-Methionine
DB00135 L-Tyrosine
DB00138 L-Cystine
DB00140 Riboflavin
DB00142 L-Glutamic Acid
DB00145 Glycine
DB00149 L-Leucine
DB00150 L-Tryptophan
DB00151 L-Cysteine
DB00156 L-Threonine
DB00158 Folic Acid
DB00160 L-Alanine
DB00161 L-Valine
DB00167 L-Isoleucine
DB00170 Menadione
DB00172 L-Proline
DB00174 L-Asparagine
DB00176 Fluvoxamine
DB00184 Nicotine
DB00200 Hydroxocobalamin
DB00201 Caffeine
DB00203 Sildenafil
DB00208 Ticlopidine
DB00215 Citalopram
DB00228 Enflurane
DB00250 Dapsone
DB00255 Diethylstilbestrol
DB00257 Clotrimazole
DB00259 Sulfanilamide
DB00277 Theophylline
DB00279 Liothyronine
DB00286 Conjugated Estrogens
DB00316 Acetaminophen
DB00321 Amitriptyline
DB00323 Tolcapone
DB00347 Trimethadione
DB00356 Chlorzoxazone
DB00359 Sulfadiazine
DB00363 Clozapine
DB00371 Meprobamate
DB00379 Mexiletine
DB00428 Streptozocin
DB00458 Imipramine
DB00466 Picrotoxin
DB00468 Quinine
DB00477 Chlorpromazine
DB00494 Entacapone
DB00501 Cimetidine
DB00503 Ritonavir
DB00514 Dextromethorphan
DB00526 Oxaliplatin
DB00540 Nortriptyline
DB00542 Benazepril
DB00544 Fluorouracil
DB00549 Zafirlukast
DB00563 Methotrexate
DB00586 Diclofenac
DB00593 Ethosuximide
DB00599 Thiopental
DB00617 Paramethadione
DB00622 Nicardipine
DB00623 Fluphenazine
DB00633 Dexmedetomidine
DB00636 Clofibrate
DB00655 Estrone
DB00675 Tamoxifen
DB00679 Thioridazine
DB00683 Midazolam
DB00690 Flurazepam
DB00703 Methazolamide
DB00748 Carbinoxamine
DB00752 Tranylcypromine
DB00753 Isoflurane
DB00763 Methimazole
DB00773 Etoposide
DB00780 Phenelzine
DB00818 Propofol
DB00822 Disulfiram
DB00829 Diazepam
DB00835 Brompheniramine
DB00841 Dobutamine
DB00851 Dacarbazine
DB00882 Clomifene
DB00883 Isosorbide Dinitrate
DB00898 Ethanol
DB00904 Ondansetron
DB00908 Quinidine
DB00918 Almotriptan
DB00949 Felbamate
DB00951 Isoniazid
DB00968 Methyldopa
DB00969 Alosetron
DB00972 Azelastine
DB00988 Dopamine
DB01007 Tioconazole
DB01011 Metyrapone
DB01028 Methoxyflurane
DB01037 Selegiline
DB01041 Thalidomide
DB01045 Rifampin
DB01068 Clonazepam
DB01079 Tegaserod
DB01085 Pilocarpine
DB01100 Pimozide
DB01110 Miconazole
DB01115 Nifedipine
DB01119 Diazoxide
DB01127 Econazole
DB01131 Proguanil
DB01136 Carvedilol
DB01141 Micafungin
DB01151 Desipramine
DB01156 Bupropion
DB01159 Halothane
DB01167 Itraconazole
DB01173 Orphenadrine
DB01174 Phenobarbital
DB01191 Dexfenfluramine
DB01198 Zopiclone
DB01204 Mitoxantrone
DB01212 Ceftriaxone
DB01213 Fomepizole
DB01223 Aminophylline
DB01234 Dexamethasone
DB01235 Levodopa
DB01236 Sevoflurane
DB01287 Dihydroergotoxine
DB01296 Glucosamine
DB01355 Hexobarbital
DB01394 Colchicine
DB01403 Methotrimeprazine
DB01412 Theobromine
DB01420 Testosterone Propionate
DB01435 Antipyrine
DB01544 Flunitrazepam
DB01558 Bromazepam
DB01583 Liotrix
DB01586 Ursodeoxycholic acid
DB01595 Nitrazepam
DB01628 Etoricoxib
DB01746 D-Leucine
DB01752 S-Adenosyl-L-Homocysteine
DB01786 D-Alanine
DB01917 Putrescine
DB02105 3,5-Dinitrocatechol
DB02310 3,5,6,8-Tetramethyl-N-Methyl Phenanthrolinium
DB02337 S-(D-Carboxybutyl)-L-Homocysteine
DB02556 D-Phenylalanine
DB02640 Fumagillin
DB02701 Nicotinamide
DB02893 D-Methionine
DB02952 Alpha-Aminoisobutyric Acid
DB03014 Heme
DB03086 N'-(2s,3r)-3-Amino-4-Cyclohexyl-2-Hydroxy-Butano-N-(4-Methylphenyl)Hydrazide
DB03107 Beta-Alanine
DB03191 3-Oxiran-2ylalanine
DB03225 D-Tryptophan
DB03336 BIA
DB03396 (E)-(2r,3r,4s,5r)-3,4,5-Trihydroxy-2-Methoxy-8,8-Dimethyl-Non-6-Enoic Acid ((3s,6r)-6-Hydroxy-2-Oxo-Azepan-3-Yl)-Amide
DB03431 Adenosine-5'-Diphosphate
DB03611 L-2-Amino-4-Methoxy-Cis-but-3-Enoic Acid
DB03754 Tris(Hydroxymethyl)Aminomethane
DB03783 Phenacetin
DB03839 D-Tyrosine
DB03900 2-Methyl-2-Propanol
DB03907 N-{3-[5-(6-Amino-Purin-9-Yl)-3,4-Dihydroxy-Tetrahydro-Furan-2-Yl]-Allyl}-2,3-Dihydroxy-5-Nitro-Benzamide
DB03929 D-Serine
DB04077 Glycerol
DB04108 (2s,3r)-3-Amino-2-Hydroxy-5-(Ethylsulfanyl)Pentanoyl-((S)-(-)-(1-Naphthyl)Ethyl)Amide
DB04272 Citric Acid
DB04324 Ovalicin
DB04398 Lactic Acid
DB04447 1,4-Dithiothreitol
DB04794 Bifonazole
DB04820 Nialamide
DB04920 Clevidipine
DB04946 Iloperidone
DB05109 Trabectedin
DB06201 Rufinamide
DB06262 Droxidopa
DB06637 Dalfampridine
DB06689 Ethanolamine Oleate
DB06712 Nilvadipine
DB06728 Aniline
DB06770 Benzyl alcohol
DB07309 5-BROMO-2-{[(4-CHLOROPHENYL)SULFONYL]AMINO}BENZOIC ACID
DB07313 5-METHYL-2-[(PHENYLSULFONYL)AMINO]BENZOIC ACID
DB07322 2-[(PHENYLSULFONYL)AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE-1-CARBOXYLIC ACID
DB07323 2-[({2-[(1Z)-3-(DIMETHYLAMINO)PROP-1-ENYL]-4-FLUOROPHENYL}SULFONYL)AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE-1-CARBOXYLIC ACID
DB07377 N'-((2S,3R)-3-AMINO-2-HYDROXY-5-(ISOPROPYLSULFANYL)PENTANOYL)-N-3-CHLOROBENZOYL HYDRAZIDE
DB07462 (3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE
DB07746 3-ETHYL-6-{[(4-FLUOROPHENYL)SULFONYL]AMINO}-2-METHYLBENZOIC ACID
DB08049 7,8-dihydroxy-4-phenyl-2H-chromen-2-one
DB08163 5'-{[4-(aminooxy)butyl](methyl)amino}-5'-deoxy-8-ethenyladenosine
DB08633 (CHLOROACETYL)CARBAMIC ACID (3R,4S,5S,5R)-5-METHOXY-4-[(2R,3R)-2-METHYL-3-(3-METHYL-2-BUTENYL)OXIRANYL]-1-OXASPIRO[2.5]OCT-6-YL ESTER
DB08794 Ethyl biscoumacetate
DB08846 Ellagic Acid
DB08868 Fingolimod