DT-Web

DB01752 - S-Adenosyl-L-Homocysteine


Identification
Name S-Adenosyl-L-Homocysteine
Accession Number DB01752 (EXPT02842)
Type small molecule
Description 5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. Formed from S-adenosylmethionine after transmethylation reactions. [PubChem]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 384.411
Groups experimental
Monoisotopic Weight 384.12158847
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Protein methyltransferase hemK
Name Protein methyltransferase hemK
Gene Name hemK
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.2163
Cap-specific mRNA
Name Cap-specific mRNA
Gene Name PAPS
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 2.3796
Cobalt-precorrin-4 C(11)-methyltransferase
Name Cobalt-precorrin-4 C(11)-methyltransferase
Gene Name cbiF
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.2166
Protein-L-isoaspartate(D-aspartate) O-methyltransferase
Name Protein-L-isoaspartate(D-aspartate) O-methyltransferase
Gene Name PCMT1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.2164
Genome polyprotein
Name Genome polyprotein
Gene Name Not Available
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.553
Phenylethanolamine N-methyltransferase
Name Phenylethanolamine N-methyltransferase
Gene Name PNMT
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 2.5689
Cyclopropane-fatty-acyl-phospholipid synthase 2
Name Cyclopropane-fatty-acyl-phospholipid synthase 2
Gene Name cmaA2
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 2.0561
Modification methylase RsrI
Name Modification methylase RsrI
Gene Name rsrIM
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 2.0062
HemK protein
Name HemK protein
Gene Name TM_0488
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 2.0552
Protein arginine N-methyltransferase 3
Name Protein arginine N-methyltransferase 3
Gene Name PRMT3
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Histamine N-methyltransferase
Name Histamine N-methyltransferase
Gene Name HNMT
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.2752
S-adenosyl-L-methionine-dependent methyltransferase mraW
Name S-adenosyl-L-methionine-dependent methyltransferase mraW
Gene Name rsmH
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.2163
rRNA adenine N-6-methyltransferase
Name rRNA adenine N-6-methyltransferase
Gene Name ermC'
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.826
tRNA
Name tRNA
Gene Name TRDMT1
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.9344
Glycine N-methyltransferase
Name Glycine N-methyltransferase
Gene Name GNMT
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.8944
Probable tRNA/rRNA methyltransferase HI0766
Name Probable tRNA/rRNA methyltransferase HI0766
Gene Name trmL
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.2166
Modification methylase PvuII
Name Modification methylase PvuII
Gene Name pvuIIM
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.2159
DNA adenine methylase
Name DNA adenine methylase
Gene Name DAM
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.2162
Mycolic acid synthase
Name Mycolic acid synthase
Gene Name pcaA
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.2185
Protein arginine N-methyltransferase 1
Name Protein arginine N-methyltransferase 1
Gene Name PRMT1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Siroheme synthase
Name Siroheme synthase
Gene Name cysG
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.0163
Modification methylase HhaI
Name Modification methylase HhaI
Gene Name hhaIM
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.2162
Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7
Name Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7
Gene Name SETD7
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.2158
tRNA
Name tRNA
Gene Name trmD
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.9344
METHOXY MYCOLIC ACID SYNTHASE 2 MMAA2
Name METHOXY MYCOLIC ACID SYNTHASE 2 MMAA2
Gene Name mmaA2
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 2.0577
Diphthine synthase
Name Diphthine synthase
Gene Name DPH5
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
RdmB
Name RdmB
Gene Name rdmB
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 2.3395
tRNA
Name tRNA
Gene Name trmD
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.9344
Uroporphyrinogen-III C-methyltransferase
Name Uroporphyrinogen-III C-methyltransferase
Gene Name cobA
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.2169
Hypothetical protein TTHA0667
Name Hypothetical protein TTHA0667
Gene Name TTHA0667
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.2172
Chemotaxis protein methyltransferase
Name Chemotaxis protein methyltransferase
Gene Name cheR
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.2163
Modification methylase TaqI
Name Modification methylase TaqI
Gene Name taqIM
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.8257
Protein-L-isoaspartate O-methyltransferase
Name Protein-L-isoaspartate O-methyltransferase
Gene Name pcm
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.2163
Catechol O-methyltransferase domain-containing protein 1
Name Catechol O-methyltransferase domain-containing protein 1
Gene Name COMTD1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Carminomycin 4-O-methyltransferase
Name Carminomycin 4-O-methyltransferase
Gene Name dnrK
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 2.0545
Guanidinoacetate N-methyltransferase
Name Guanidinoacetate N-methyltransferase
Gene Name GAMT
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.2705

Enzymes


Histamine N-methyltransferase
Name Histamine N-methyltransferase
Gene Name HNMT
Actions Not Available
References Not Available
DTHybrid score 1.2752

Predictions


Id Partner name Gene Name Score
2297 Genome polyprotein Not Available 1.553
2694 Genome polyprotein Not Available 1.553
2719 Genome polyprotein Not Available 1.553
2860 Genome polyprotein Not Available 1.553
2928 Genome polyprotein Not Available 1.553
3160 Genome polyprotein Not Available 1.553
3260 Genome polyprotein Not Available 1.553
4783 Genome polyprotein Not Available 1.553
5726 Genome polyprotein Not Available 1.553
5779 Genome polyprotein Not Available 1.553
5867 Genome polyprotein Not Available 1.553
6253 Genome polyprotein Not Available 1.553
6301 Genome polyprotein Not Available 1.553
6380 Genome polyprotein Not Available 1.553
6381 Genome polyprotein Not Available 1.553
6437 Genome polyprotein Not Available 1.553
6520 Genome polyprotein Not Available 1.553
6521 Genome polyprotein Not Available 1.553
6652 Genome polyprotein Not Available 1.553
6734 Genome polyprotein Not Available 1.553
6735 Genome polyprotein Not Available 1.553
6736 Genome polyprotein Not Available 1.553
6737 Genome polyprotein Not Available 1.553
6738 Genome polyprotein Not Available 1.553
6739 Genome polyprotein Not Available 1.553
6744 Genome polyprotein Not Available 1.553
6748 Genome polyprotein Not Available 1.553
6894 Genome polyprotein Not Available 1.553
6898 Genome polyprotein Not Available 1.553
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.282
1958 S-methyl-5-thioadenosine phosphorylase MTAP 0.2439
2417 Chloramphenicol acetyltransferase cat 0.1004
3278 Chloramphenicol acetyltransferase cat 0.1004
1286 Eukaryotic translation initiation factor 4E EIF4E 0.0749
2247 Scavenger mRNA-decapping enzyme DcpS DCPS 0.0695
92 Creatine kinase B-type CKB 0.0665
414 Sodium- and chloride-dependent creatine transporter 1 SLC6A8 0.0665
192 Creatine kinase, ubiquitous mitochondrial CKMT1A 0.0665
456 Creatine kinase, sarcomeric mitochondrial CKMT2 0.0665
330 Spermidine synthase SRM 0.0572
3038 Spermidine synthase speE 0.0572
788 Creatine kinase M-type CKM 0.0535
740 Argininosuccinate synthase ASS1 0.0514
865 Argininosuccinate synthase ASS1 0.0514
2680 Argininosuccinate synthase argG 0.0514
3194 Argininosuccinate synthase argG 0.0514
334 S-adenosylmethionine synthetase isoform type-2 MAT2A 0.0469
118 Organic cation/carnitine transporter 2 SLC22A5 0.0454
113 S-adenosylmethionine decarboxylase proenzyme AMD1 0.0435
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.0433
3602 Anti-sigma F factor antagonist spoIIAA 0.0393
2514 Phosphocarrier protein HPr ptsH 0.0393
5689 Phosphocarrier protein HPr ptsH 0.0393
358 Cystathionine beta-synthase CBS 0.0393
5686 Potassium voltage-gated channel subfamily C member 4 KCNC4 0.0393
6024 Cytochrome P450 1A1 CYP1A1 0.0362
5126 Arginase rocF 0.0361
4119 Cytochrome P450 2D6 CYP2D6 0.035
6144 Solute carrier family 22 member 2 SLC22A2 0.0345
1130 Lithostathine 1 alpha REG1A 0.0342
4542 Glutaminase 1 glsA1 0.0342
4544 Glutaminase 1 glsA1 0.0342
4924 Cytochrome P450 2C8 CYP2C8 0.0319
3119 Fimbrial protein pilE1 0.0316
2530 Protein kinase C theta type PRKCQ 0.0315
468 Cytochrome P450 4A11 CYP4A11 0.0313
1759 85 kDa calcium-independent phospholipase A2 PLA2G6 0.0312
1770 Phospholipase C PLCL1 0.0312
2841 Phospholipase C plc 0.0312
3453 Alkaline phosphatase phoA 0.0298
4512 Cytochrome P450 3A4 CYP3A4 0.0287
4118 Cytochrome P450 3A5 CYP3A5 0.0286
2503 Phosphomannomutase/phosphoglucomutase algC 0.0285
5150 Endo-1,4-beta-xylanase Y xynY 0.0285
3810 Catechol O-methyltransferase COMT 0.028
3238 Multidrug resistance protein mexA mexA 0.0266
3336 C4-dicarboxylate transport transcriptional regulatory protein dctD dctD 0.0265
3116 Bacterioferritin bfr 0.0265
4906 Bacterioferritin bfr 0.0265
4965 Bacterioferritin bfr 0.0265
5489 Ribonucleoside-diphosphate reductase 1 subunit beta nrdB 0.0265
3173 Enolase eno 0.0265
3709 Glycerol uptake facilitator protein glpF 0.0265
3393 TGF-beta receptor type-2 TGFBR2 0.0265
6147 Solute carrier family 22 member 3 SLC22A3 0.0249
3191 Histidinol dehydrogenase hisD 0.0247
6013 Cytochrome P450 2E1 CYP2E1 0.0247
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0238
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0234
2852 DNA mismatch repair protein mutL mutL 0.0231
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.023
5682 Ribonuclease pancreatic RNASE1 0.023
10 Glycogen phosphorylase, liver form PYGL 0.0228
2207 Rhodopsin RHO 0.0224
6459 Glycodelin PAEP 0.0216
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0212
6145 Solute carrier family 22 member 1 SLC22A1 0.0211
3221 Cytochrome c4 cc4 0.021
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0209
723 Cytosolic phospholipase A2 PLA2G4A 0.0197
4692 A/G-specific adenine glycosylase mutY 0.0195
1898 Cytochrome P450 1B1 CYP1B1 0.0191
1341 Histamine H3 receptor HRH3 0.0191
4757 Cytochrome P450 2C9 CYP2C9 0.019
2300 Lysozyme E 0.0188
3633 Lysozyme R 0.0188
5597 Lysozyme 17 0.0188
444 Alcohol dehydrogenase 1B ADH1B 0.0187
2802 Endoglucanase G celCCG 0.0185
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0184
6316 ADP-ribosylation factor 1 ARF1 0.0181
1152 Glycogen phosphorylase, muscle form PYGM 0.0179
6016 Cytochrome P450 2C19 CYP2C19 0.0174
4200 Cytochrome P450 1A2 CYP1A2 0.0171
164 Histamine H4 receptor HRH4 0.0168
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0163
1588 Multidrug resistance protein 1 ABCB1 0.0161
833 Organic cation/carnitine transporter 1 SLC22A4 0.0157
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.0157
6142 Solute carrier family 22 member 8 SLC22A8 0.0128
904 Glutathione S-transferase P GSTP1 0.0127
124 Histamine H2 receptor HRH2 0.0122
4055 Bile acid CoA:amino acid N-acyltransferase BAAT 0.012
4061 Peroxisomal sarcosine oxidase PIPOX 0.0119
4058 Glycine N-acyltransferase-like protein 2 GLYATL2 0.0119
4057 Glycine N-acyltransferase GLYAT 0.0119
4059 Glycine N-acyltransferase-like protein 1 GLYATL1 0.0119
4056 N-arachidonyl glycine receptor GPR18 0.0119
1236 Sodium- and chloride-dependent glycine transporter 1 SLC6A9 0.0119
1466 Glycyl-tRNA synthetase GARS 0.0119
4062 Sodium- and chloride-dependent glycine transporter 2 SLC6A5 0.0119
4060 Vesicular inhibitory amino acid transporter SLC32A1 0.0119
1088 5-aminolevulinate synthase, erythroid-specific, mitochondrial ALAS2 0.0119
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0113
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0113
4054 Glycine cleavage system H protein, mitochondrial GCSH 0.0103
62 Glycine receptor subunit beta GLRB 0.0095
575 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial GCAT 0.0095
455 5-aminolevulinate synthase, nonspecific, mitochondrial ALAS1 0.0094
681 Glycine dehydrogenase [decarboxylating], mitochondrial GLDC 0.0094
383 Glycine amidinotransferase, mitochondrial GATM 0.0092
207 Glutathione synthetase GSS 0.009
5269 Glutathione synthetase gshB 0.009
3884 SHMT2 protein SHMT2 0.0085
3901 SHMT2 protein SHMT2 0.0085
3885 Hypothetical protein DKFZp686P09201 DKFZp686P09201 0.0085
3879 Serine hydroxymethyltransferase 2 Not Available 0.0085
321 Serine hydroxymethyltransferase, mitochondrial SHMT2 0.0085
114 Alanine--glyoxylate aminotransferase 2, mitochondrial AGXT2 0.0083
349 Serine--pyruvate aminotransferase AGXT 0.0082
492 Histamine H1 receptor HRH1 0.0082
593 Proton-coupled amino acid transporter 1 SLC36A1 0.0082
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.008
367 Serine hydroxymethyltransferase, cytosolic SHMT1 0.0079
461 Glycine receptor subunit alpha-3 GLRA3 0.0078
820 Glycine receptor subunit alpha-2 GLRA2 0.0077
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.0075
5583 RNA 3'-terminal phosphate cyclase rtcA 0.0073
5577 N5-carboxyaminoimidazole ribonucleotide mutase purE 0.0073
5588 Cell division protein FtsY TM_0570 0.0073
5591 Complement component C8 gamma chain C8G 0.0073
3792 KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase eda 0.0073
5582 Regulator of transcription; stringent starvation protein A sspA 0.0073
4238 50S ribosomal protein L4 rplD 0.0073
5578 50S ribosomal protein L4 rplD 0.0073
6173 50S ribosomal protein L4 rplD 0.0073
6219 50S ribosomal protein L4 rplD 0.0073
4695 UPF0124 protein yfiH yfiH 0.0073
5060 Intron-associated endonuclease 1 ITEVIR 0.0073
5590 N utilization substance protein B homolog nusB 0.0073
5598 Glycerol uptake operon antiterminator-related protein TM_1436 0.0073
5600 Pyruvate decarboxylase pdc 0.0073
2838 Ribose-5-phosphate isomerase A rpiA 0.0073
2952 Ribose-5-phosphate isomerase A rpiA 0.0073
5595 Ribose-5-phosphate isomerase A rpiA 0.0073
5586 Pleckstrin homology domain-containing family A member 1 PLEKHA1 0.0073
5593 Transferase Not Available 0.0073
4375 Glutamine synthetase 1 glnA1 0.0073
5575 Short tail fiber protein 12 0.0073
5592 Ribonucleoside-diphosphate reductase subunit beta nrdF 0.0073
5587 Iron(III)-binding periplasmic protein fbpA 0.0073
5581 Beta-fructosidase bfrA 0.0073
5580 Hexon protein PII 0.0073
5574 Invasin YPTB1668 0.0073
4992 Cytochrome c peroxidase Not Available 0.007
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0069
482 Glycine receptor subunit alpha-1 GLRA1 0.0066
5006 RNASE4 protein RNASE4 0.0064
4533 Glyoxalase family protein BC_1747 0.0064
2555 Pol polyprotein pol 0.0064
3242 Pol polyprotein gag-pol 0.0064
3471 Pol polyprotein gag-pro-pol 0.0064
5256 Pol polyprotein pol 0.0064
6469 Pol polyprotein gag-pol 0.0064
6565 Pol polyprotein Not Available 0.0064
3085 Molybdopterin-guanine dinucleotide biosynthesis protein A mobA 0.0064
5328 Prostaglandin F synthase Tb11.02.2310 0.0063
3132 Tryptophan synthase alpha chain trpA 0.0062
6568 Tryptophan synthase alpha chain trpA 0.0062
5599 3-carboxy-cis,cis-muconate cycloisomerase pcaB 0.0062
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0062
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0062
1467 Tumor necrosis factor ligand superfamily member 13B TNFSF13B 0.0062
2521 Cell division protein ftsZ ftsZ 0.0059
3301 Cell division protein ftsZ ftsZ 0.0059
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0059
2603 Beta-lactamase II blm 0.0058
2149 Angiogenin ANG 0.0058
3583 6-phosphogluconolactonase pgl 0.0058
6151 Monocarboxylate transporter 10 SLC16A10 0.0058
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.0058
857 Malate dehydrogenase, mitochondrial MDH2 0.0057
941 Betaine--homocysteine S-methyltransferase 1 BHMT 0.0056
3486 Fumarate hydratase class II fumC 0.0055
2942 Sialidase nanH 0.0054
3546 Sialidase nedA 0.0054
2869 1-deoxy-D-xylulose 5-phosphate reductoisomerase dxr 0.0054
1123 Eosinophil cationic protein RNASE3 0.0054
332 Beta-lactamase blaZ 0.0054
2478 Beta-lactamase ampC 0.0054
2613 Beta-lactamase ampC 0.0054
2635 Beta-lactamase ampC 0.0054
2700 Beta-lactamase penP 0.0054
5445 Beta-lactamase blaB 0.0054
6019 Beta-lactamase SHV-7 0.0054
6701 Beta-lactamase cphA 0.0054
2805 Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 HS3ST3A1 0.0053
2697 Uridine-cytidine kinase 2 UCK2 0.0053
2452 Tryptophanyl-tRNA synthetase trpS 0.0052
4428 Redox-sensing transcriptional repressor rex rex 0.005
4423 Levodione reductase lvr 0.005
3381 Alcohol dehydrogenase Not Available 0.005
4508 Alcohol dehydrogenase adhA 0.005
4336 Glyceraldehyde 3-phosphate dehydrogenase Not Available 0.005
4436 Glyceraldehyde 3-phosphate dehydrogenase tthHB8IM 0.005
4447 Hypothetical protein yhfP yhfP 0.005
4414 Dehydrogenase TT_P0035 0.005
4443 Quinate/shikimate dehydrogenase ydiB 0.005
4418 AGR_L_3209p AGR_L_3209 0.005
4495 3-oxoacyl-(Acyl carrier protein) reductase TM_1169 0.005
4435 L-aspartate dehydrogenase nadX 0.005
4446 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase Not Available 0.005
4505 Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase bphB 0.005
4456 Inorganic polyphosphate/ATP-NAD kinase ppnK 0.005
4448 L-2-hydroxyisocaproate dehydrogenase Not Available 0.005
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.005
3726 D-3-phosphoglycerate dehydrogenase serA 0.005
4291 D-3-phosphoglycerate dehydrogenase serA 0.005
4500 L-lactate dehydrogenase 2 ldh2 0.005
4471 CDP-D-glucose-4,6-dehydratase ascB 0.005
4507 Alanine dehydrogenase ald 0.005
4475 Hypothetical protein Rv0046c/MT0052 ino1 0.005
4455 Glycerol dehydrogenase gldA 0.005
4497 Benzyl alcohol dehydrogenase xylB 0.005
4449 ADP-ribosyltransferase Not Available 0.005
4506 Myo-inositol-1-phosphate synthase-related protein TM_1419 0.005
3735 NAD(P) transhydrogenase subunit alpha part 1 pntAA 0.005
4466 Glutathione-independent formaldehyde dehydrogenase fdhA 0.005
4502 Formate dehydrogenase Not Available 0.005
3729 Citrate synthase gltA 0.005
4575 Citrate synthase cit 0.005
4580 Citrate synthase gltA 0.005
4451 Vip2Ac vip2Ac 0.005
4472 Glucose 1-dehydrogenase Not Available 0.005
4467 Alpha-glucosidase, putative TM_0752 0.005
2350 3-isopropylmalate dehydrogenase leuB 0.005
3092 3-isopropylmalate dehydrogenase leuB 0.005
4487 Transcriptional regulator nadR nadR 0.005
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.005
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.005
3478 Glucose-1-phosphate thymidylyltransferase rmlA 0.0047
4277 Glucose-1-phosphate thymidylyltransferase rmlA 0.0047
5579 Carboxypeptidase B CPB1 0.0047
128 Adenine phosphoribosyltransferase APRT 0.0047
3384 Macrophage migration inhibitory factor MIF 0.0046
3615 Dihydrodipicolinate reductase dapB 0.0043
3618 Dihydrodipicolinate reductase dapB 0.0043
4462 Dihydrodipicolinate reductase dapB 0.0043
4486 Phenol 2-hydroxylase component B pheA2 0.0043
4439 Ferredoxin reductase bphA4 0.0043
4427 TDP-glucose-4,6-dehydratase desIV 0.0043
6698 Dehydrogenase/reductase SDR family member 4-like 2 DHRS4L2 0.0043
4503 NADPH-flavin oxidoreductase frp 0.0043
2831 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase Not Available 0.0043
3059 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase fabG3 0.0043
4509 Acetoin(diacetyl) reductase budC 0.0043
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0043
4477 Dihydrolipoyl dehydrogenase lpdV 0.0043
5077 Dihydrolipoyl dehydrogenase Not Available 0.0043
5117 Dihydrolipoyl dehydrogenase lpd 0.0043
3598 dTDP-4-dehydrorhamnose reductase rfbD 0.0043
2424 L-lactate dehydrogenase ldh 0.0043
2641 L-lactate dehydrogenase Not Available 0.0043
4437 L-lactate dehydrogenase ldh 0.0043
4442 L-lactate dehydrogenase ldh 0.0043
2336 2,3-diketo-L-gulonate reductase dlgD 0.0043
3401 D-2-hydroxyisocaproate dehydrogenase Not Available 0.0043
126 D-lactate dehydrogenase dld 0.0043
3545 D-lactate dehydrogenase Not Available 0.0043
4510 D-lactate dehydrogenase ldhA 0.0043
2967 CDP-paratose 2-epimerase rfbE 0.0043
4498 Ornithine cyclodeaminase PP3533 0.0043
3081 3-dehydroquinate synthase aroB 0.0043
2591 Urocanate hydratase hutU 0.0043
3177 dTDP-glucose 4,6-dehydratase rfbB 0.0043
4499 dTDP-glucose 4,6-dehydratase rmlB 0.0043
2018 Deoxyhypusine synthase DHPS 0.0043
4482 UDP-galactose 4-epimerase galE 0.0043
2538 6-phospho-beta-glucosidase bglT bglT 0.0043
4496 C-terminal-binding protein 1 CTBP1 0.0043
2393 Maltose-6'-phosphate glucosidase glvA 0.0043
3671 7-alpha-hydroxysteroid dehydrogenase hdhA 0.0043
2881 Gamma-aminobutyraldehyde dehydrogenase prr 0.0043
2507 Diphtheria toxin Not Available 0.0043
4450 Iota toxin component Ia Not Available 0.0043
1199 GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 ART1 0.0043
2683 Mono-ADP-ribosyltransferase C3 C3 0.004
3296 Nicotinamide mononucleotide adenylyltransferase 1 NMNAT1 0.004
4343 Alpha-glucosidase aglA 0.004
3736 Glyceraldehyde-3-phosphate dehydrogenase A gapA 0.004
4504 WbpP Not Available 0.004
711 UDP-glucose 6-dehydrogenase UGDH 0.004
3672 UDP-glucose 6-dehydrogenase hasB 0.004
3367 GDP-mannose 6-dehydrogenase algD 0.004
2799 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal Not Available 0.004
4440 NADH peroxidase npr 0.004
816 Biliverdin reductase A BLVRA 0.0039
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0039
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0039
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0039
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0038
4476 Mannitol dehydrogenase mtlD 0.0038
3333 Nicotinamide mononucleotide adenylyltransferase 3 NMNAT3 0.0038
2434 NH(3)-dependent NAD(+) synthetase nadE 0.0038
2910 NH(3)-dependent NAD(+) synthetase nadE 0.0038
3217 NH(3)-dependent NAD(+) synthetase nadE 0.0038
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.0038
2617 Nitric oxide synthase oxygenase nos 0.0038
2701 Nitric oxide synthase oxygenase nos 0.0038
3070 Adenosylhomocysteinase AHCY 0.0038
4424 Adenosylhomocysteinase PFE1050w 0.0038
6278 Adenosylhomocysteinase ahcY 0.0038
2826 Glucose--fructose oxidoreductase gfo 0.0038
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.0038
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.0038
63 Malate dehydrogenase mdh 0.0037
2329 Malate dehydrogenase mdh 0.0037
3445 Malate dehydrogenase mdh 0.0037
4420 Malate dehydrogenase mdh 0.0037
4438 Malate dehydrogenase mdh 0.0037
597 Dihydropteridine reductase QDPR 0.0037
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0037
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.0037
646 Malate dehydrogenase, cytoplasmic MDH1 0.0037
328 Sorbitol dehydrogenase SORD 0.0037
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.0037
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0037
363 NADP-dependent malic enzyme, mitochondrial ME3 0.0037
396 Alcohol dehydrogenase 4 ADH4 0.0037
327 Glutathione reductase gor 0.0036
5110 Glutathione reductase GR2 0.0036
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0036
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0036
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0036
822 Aldose reductase AKR1B1 0.0036
77 L-lactate dehydrogenase B chain LDHB 0.0036
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.0036
12 Alcohol dehydrogenase class 3 ADH5 0.0036
2286 Isocitrate dehydrogenase [NADP] icd 0.0035
2302 Isocitrate dehydrogenase [NADP] icd 0.0035
2771 Isocitrate dehydrogenase [NADP] icd 0.0035
4491 DNA ligase, NAD-dependent ligA 0.0035
473 L-lactate dehydrogenase A chain LDHA 0.0035
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0035
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0035
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0035
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0035
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0035
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0035
2762 UDP-glucose 4-epimerase GALE 0.0034
3461 UDP-glucose 4-epimerase galE 0.0034
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0034
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0033
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0033
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0031
611 Retinal dehydrogenase 1 ALDH1A1 0.0031
569 Retinal dehydrogenase 2 ALDH1A2 0.0031
251 Alcohol dehydrogenase 1A ADH1A 0.003
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.003
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0029
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0028
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0028
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0028
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0028
714 Glutathione reductase, mitochondrial GSR 0.0028
517 Alcohol dehydrogenase 1C ADH1C 0.0026
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