Partner ID 1466
Name Glycyl-tRNA synthetase
Synonyms 3240
Gene name GARS
General function Translation, ribosomal structure and biogenesis
Specific function ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)
Gene sequence + ...

ATGCCCTCTCCGCGTCCAGTGCTGCTTAGAGGTGCTCGCGCCGCTCTGCTGCTGCTGCTGCCGCCCCGGCTCTTAGCCCGACCCTCGCTCCTGCTCCGCCGGTCCCTCAGCGCGGCCTCCTGCGCCCCGATCTCCTTGCCCGCCGCCGCCTCCCGGAGCAGCATGGACGGCGCGGGGGCTGAGGAGGTGCTGGCACCTCTGAGGCTAGCAGTGCGCCAGCAGGGAGATCTTGTGCGAAAACTCAAAGAAGATAAAGCACCCCAAGTAGACGTAGACAAAGCAGTGGCTGAGCTCAAAGCCCGCAAGAGGGTTCTGGAAGCAAAGGAGCTGGCGTTACAGCCCAAAGATGATATTGTAGACCGAGCAAAAATGGAAGATACCCTGAAGAGGAGGTTTTTCTATGATCAAGCTTTTGCTATTTATGGAGGTGTTAGTGGTCTGTATGACTTTGGGCCAGTTGGCTGTGCTTTGAAGAACAATATTATTCAGACCTGGAGGCAGCACTTTATCCAAGAGGAACAGATCCTGGAGATCGATTGCACCATGCTCACCCCTGAGCCAGTTTTAAAGACCTCTGGCCATGTAGACAAATTTGCTGACTTCATGGTGAAAGACGTAAAAAATGGAGAATGTTTTCGTGCTGACCATCTATTAAAAGCTCATTTACAGAAATTGATGTCTGATAAGAAGTGTTCTGTCGAAAAGAAATCAGAAATGGAAAGTGTTTTGGCCCAGCTTGATAACTATGGACAGCAAGAACTTGCGGATCTTTTTGTGAACTATAATGTAAAATCTCCCATTACTGGAAATGATCTATCCCCTCCAGTGTCTTTTAACTTAATGTTCAAGACTTTCATTGGGCCTGGAGGAAACATGCCTGGGTACTTGAGACCAGAAACTGCACAGGGGATTTTCTTGAATTTCAAACGACTTTTGGAGTTCAACCAAGGAAAGTTGCCTTTTGCTGCTGCCCAGATTGGAAATTCTTTTAGAAATGAGATCTCCCCTCGATCTGGACTGATCAGAGTCAGAGAATTCACAATGGCAGAAATTGAGCACTTTGTAGATCCCAGTGAGAAAGACCACCCCAAGTTCCAGAATGTGGCAGACCTTCACCTTTATTTGTATTCAGCAAAAGCCCAGGTCAGCGGACAGTCCGCTCGGAAAATGCGCCTGGGAGATGCTGTTGAACAGGGTGTGATTAATAACACAGTATTAGGCTATTTCATTGGCCGCATCTACCTCTACCTCACGAAGGTTGGAATATCTCCAGATAAACTCCGCTTCCGGCAGCACATGGAGAATGAGATGGCCCATTATGCCTGTGACTGTTGGGATGCAGAATCCAAAACATCCTACGGTTGGATTGAGATTGTTGGATGTGCTGATCGTTCCTGTTATGACCTCTCCTGTCATGCACGAGCCACCAAAGTCCCACTTGTAGCTGAGAAACCTCTGAAAGAACCCAAAACAGTCAATGTTGTTCAGTTTGAACCCAGTAAGGGAGCAATTGGTAAGGCATATAAGAAGGATGCAAAACTGGTGATGGAGTATCTTGCCATTTGTGATGAGTGCTACATTACAGAAATGGAGATGCTGCTGAATGAGAAAGGGGAATTCACAATTGAAACTGAAGGGAAAACATTTCAGTTAACAAAAGACATGATCAATGTGAAGAGATTCCAGAAAACACTATATGTGGAAGAAGTTGTTCCGAATGTAATTGAACCTTCCTTCGGCCTGGGTAGGATCATGTATACGGTATTTGAACATACATTCCATGTACGAGAAGGAGATGAACAGAGAACATTCTTCAGTTTCCCTGCTGTAGTTGCTCCATTCAAATGTTCCGTCCTCCCACTGAGCCAAAACCAGGAGTTCATGCCATTTGTCAAGGAATTATCGGAAGCCCTGACCAGGCATGGAGTATCTCACAAAGTAGACGATTCCTCTGGGTCAATCGGAAGGCGCTATGCCAGGACTGATGAGATTGGCGTGGCTTTTGGTGTCACCATTGACTTTGACACAGTGAACAAGACCCCCCACACTGCAACTCTGAGGGACCGTGACTCAATGCGGCAGATAAGAGCAGAGATCTCTGAGCTGCCCAGCATAGTCCAAGACCTAGCCAATGGCAACATCACATGGGCTGATGTGGAGGCCAGGTATCCTCTGTTTGAAGGGCAAGAGACTGGTAAAAAAGAGACAATCGAGGAATGA

Protein sequence + ...

MPSPRPVLLRGARAALLLLLPPRLLARPSLLLRRSLSAASCAPISLPAAASRSSMDGAGAEEVLAPLRLAVRQQGDLVRKLKEDKAPQVDVDKAVAELKARKRVLEAKELALQPKDDIVDRAKMEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADFMVKDVKNGECFRADHLLKAHLQKLMSDKKCSVEKKSEMESVLAQLDNYGQQELADLFVNYNVKSPITGNDLSPPVSFNLMFKTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHPKFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGISPDKLRFRQHMENEMAHYACDCWDAESKTSYGWIEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKTVNVVQFEPSKGAIGKAYKKDAKLVMEYLAICDECYITEMEMLLNEKGEFTIETEGKTFQLTKDMINVKRFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTDEIGVAFGVTIDFDTVNKTPHTATLRDRDSMRQIRAEISELPSIVQDLANGNITWADVEARYPLFEGQETGKKETIEE

GO Classification
function
adenyl nucleotide binding
glycine-tRNA ligase activity
ATP binding
binding
ligase activity
ligase activity, forming phosphoric ester bonds
nucleotide binding
RNA ligase activity
catalytic activity
tRNA ligase activity
purine nucleotide binding
process
tRNA aminoacylation for protein translation
glycyl-tRNA aminoacylation
macromolecule biosynthesis
protein biosynthesis
nucleobase, nucleoside, nucleotide and nucleic acid metabolism
physiological process
metabolism
RNA metabolism
cellular metabolism
tRNA metabolism
macromolecule metabolism
tRNA aminoacylation
See more information at   →   www.drugbank.ca
Id Name
DB00145 Glycine
Id Name
DB00114 Pyridoxal Phosphate
DB00116 Tetrahydrofolic acid
DB00117 L-Histidine
DB00118 S-Adenosylmethionine
DB00119 Pyruvic acid
DB00120 L-Phenylalanine
DB00123 L-Lysine
DB00125 L-Arginine
DB00128 L-Aspartic Acid
DB00129 L-Ornithine
DB00130 L-Glutamine
DB00133 L-Serine
DB00134 L-Methionine
DB00135 L-Tyrosine
DB00138 L-Cystine
DB00142 L-Glutamic Acid
DB00143 Glutathione
DB00145 Glycine
DB00149 L-Leucine
DB00150 L-Tryptophan
DB00151 L-Cysteine
DB00156 L-Threonine
DB00160 L-Alanine
DB00161 L-Valine
DB00167 L-Isoleucine
DB00172 L-Proline
DB00174 L-Asparagine
DB00228 Enflurane
DB00279 Liothyronine
DB00431 Lindane
DB00454 Meperidine
DB00466 Picrotoxin
DB00602 Ivermectin
DB00659 Acamprosate
DB00753 Isoflurane
DB00898 Ethanol
DB00949 Felbamate
DB01028 Methoxyflurane
DB01043 Memantine
DB01055 Mimosine
DB01080 Vigabatrin
DB01159 Halothane
DB01173 Orphenadrine
DB01189 Desflurane
DB01235 Levodopa
DB01236 Sevoflurane
DB01381 Ginkgo biloba
DB01520 Tenocyclidine
DB01583 Liotrix
DB01746 D-Leucine
DB01752 S-Adenosyl-L-Homocysteine
DB01786 D-Alanine
DB02067 Triglu-5-Formyl-Tetrahydrofolate
DB02068 Delta-Amino Valeric Acid
DB02079 (Aminooxy)Acetic Acid
DB02530 Gamma(Amino)-Butyric Acid
DB02556 D-Phenylalanine
DB02800 5-Hydroxymethylene-6-Hydrofolic Acid
DB02824 N-Pyridoxyl-Glycine-5-Monophosphate
DB02853 D-Proline
DB02952 Alpha-Aminoisobutyric Acid
DB03107 Beta-Alanine
DB03187 6-(Hydroxyethyldithio)-8-(Aminomethylthio)Octanoic Acid
DB03225 D-Tryptophan
DB03408 Gamma-Glutamylcysteine
DB03431 Adenosine-5'-Diphosphate
DB03760 Dihydrolipoic Acid
DB03839 D-Tyrosine
DB03929 D-Serine
DB04083 N'-Pyridoxyl-Lysine-5'-Monophosphate
DB04185 Norvaline
DB04272 Citric Acid
DB04395 Phosphoaminophosphonic Acid-Adenylate Ester
DB04398 Lactic Acid
DB04454 Alpha-Aminobutyric Acid
DB06262 Droxidopa
DB08060 4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID
DB08835 Spaglumic Acid
DB08847 Hydroxyproline